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TESDALRPSGSSRISGDSLEGVSATTLWTLHNRGTEAKRPDSVIRDPLAAELFDAIEYDYRKFGRPSQTH ALRALAFDTQARVYLATHPRAAIVALAEGMQTSFWRLGGADATAQFTWYSVDLPPVMELRNQLLPNDERI VKLAQSALDLSWMDQVDASGGAFITAEGLLMYLQPEESLGLIEACAKRFPGGQMMFDSIPHWFSRRTLQG FKLSDRYVAPPMPFALTPDEGEALISIPGVVTAIDIPLHRGRGIWKFVNSKRLDRGFLRRTRPSMTLLQF G*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_1295c | - | - | 100% (282) | O-methyltransferase OMT |
| M. abscessus ATCC 19977 | MAB_1292c | - | 1e-67 | 50.18% (273) | O-methyltransferase OMT |
| M. abscessus ATCC 19977 | MAB_0668c | - | 8e-65 | 46.97% (264) | O-methyltransferase OmT |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1184c | omt | 1e-69 | 50.57% (265) | O-methyltransferase |
| M. gilvum PYR-GCK | Mflv_5259 | - | 1e-68 | 51.13% (266) | O-methyltransferase domain-containing protein |
| M. tuberculosis H37Rv | Rv1153c | omt | 2e-70 | 50.94% (265) | O-methyltransferase |
| M. leprae Br4923 | - | - | - | - | - |
| M. marinum M | MMAR_4300 | omt_2 | 1e-72 | 52.63% (266) | O-methyltransferase Omt_2 |
| M. avium 104 | MAV_2991 | - | 2e-25 | 34.78% (184) | tetracenomycin polyketide synthesis O-methyltransferase TcmP |
| M. smegmatis MC2 155 | MSMEG_5173 | - | 8e-73 | 53.51% (271) | O-methyltransferase, putative |
| M. thermoresistible (build 8) | TH_0460 | omt | 3e-77 | 53.93% (280) | PROBABLE O-METHYLTRANSFERASE OMT |
| M. ulcerans Agy99 | MUL_4852 | omt_1 | 2e-64 | 50.18% (275) | O-methyltransferase Omt_1 |
| M. vanbaalenii PYR-1 | Mvan_0979 | - | 1e-70 | 50.00% (280) | O-methyltransferase domain-containing protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mb1184c|M.bovis_AF2122/97 MS-AHKPAKQRV------ALTGVSETALLTLNARAAEARRRDTIIDDPMA
Rv1153c|M.tuberculosis_H37Rv MS-AHKPAKQRV------ALTGVSETALLTLNARAAEARRRDAIIDDPMA
MMAR_4300|M.marinum_M MTPADEFAQQKV------ALTGVSETALLTLNARAAEARRRDPIIEDPMA
Mflv_5259|M.gilvum_PYR-GCK ------------------MLAGVSETALLTLNGRAYQARHPNAILDDPMA
Mvan_0979|M.vanbaalenii_PYR-1 MD-QDGKIDAG-------ALAGVSETALLTLNGRAYQARHPNAIIDDPMA
MSMEG_5173|M.smegmatis_MC2_155 MT-TDATARTRV------SLTGVSETALLTLQVRANEARRPDGLIKDPMA
TH_0460|M.thermoresistible__bu VS-SGPLAKP--------ELTGVSETALLTLLVRATEARRPDGIIDDPMA
MAB_1295c|M.abscessus_ATCC_199 MTESDALRPSGSSRISGDSLEGVSATTLWTLHNRGTEAKRPDSVIRDPLA
MUL_4852|M.ulcerans_Agy99 MPVIDAR-----------HLDDISETALLTLHQRATEAARPDAIIDDPMA
MAV_2991|M.avium_104 MTATEKVDFSSV------AWGSVEWTNLVTLYLRACESRSRQPILGDTAA
.:. * * ** *. :: : :: *. *
Mb1184c|M.bovis_AF2122/97 VALVESIDFGFAKFG-----PTG-QGFALRARAFDMAAQHYLDQHPAATV
Rv1153c|M.tuberculosis_H37Rv VALVESIDFDFAKFG-----PTG-QGFALRARAFDMAAQHYLDQHPAATV
MMAR_4300|M.marinum_M VRLVDSIDFDFAKFG-----PTR-QDIALRALAFDTRALAYLNKHPSATV
Mflv_5259|M.gilvum_PYR-GCK IRVVDSIDFDFDKFG-----RRKGQEMALRSLAFDRAATAYLAKHPKATV
Mvan_0979|M.vanbaalenii_PYR-1 IRLVDAIDFDFDKFG-----RRKGQEMALRSLAFDRAATRYLSRHPAATV
MSMEG_5173|M.smegmatis_MC2_155 VQLVDSIDFDFAKFG-----HSHRQDMALRSLIFDRATSDYLRDHPKATV
TH_0460|M.thermoresistible__bu VRLVDSIDFDFAKFG-----PSRRQDMALRAKAFDTATRRYLRAHPKATV
MAB_1295c|M.abscessus_ATCC_199 AELFDAIEYDYRKFG-----RPS-QTHALRALAFDTQARVYLATHPRAAI
MUL_4852|M.ulcerans_Agy99 IALRNDIDYPYHHFG-----RTH-QATALRALAFDNSTRDFLQTRPGATV
MAV_2991|M.avium_104 AEAVDRIRYDFKRIHRMSLPASNQYLVALRAVQFDDWCAEFLARHPDAVV
: * : : :: ***: ** :* :* *.:
Mb1184c|M.bovis_AF2122/97 VALAEGLQTSFWRLDVAIPGGQFRWLTVDLPPIVDLRTRLLPSSPRVSVC
Rv1153c|M.tuberculosis_H37Rv VALAEGLQTSFWRLDVAIPGGQFRWLTVDLPPIVDLRTRLLPSSPRVSVC
MMAR_4300|M.marinum_M VALAEGLQTSFWRLDSALPGKKFRWLTVDLPPIIDIRKRLLPNSPRVSVC
Mflv_5259|M.gilvum_PYR-GCK VALAEGLQTSFWRLDAALPTAEFRWLTVDFEPIIELRRRLLPESARITTL
Mvan_0979|M.vanbaalenii_PYR-1 VALAEGLQTSFWRLDAAIPDSRFRWVSIDLEPVIALRRRLLPDSPRITTL
MSMEG_5173|M.smegmatis_MC2_155 VALAEGLQTSFYRLNEAGVGDQFCWLTVDLPPMVEIRNKLLPPSDRVRTC
TH_0460|M.thermoresistible__bu VALAEGLQTSFFRLNAADVGDEFRWVTVDLAPVIELRRQLLPADDRVTML
MAB_1295c|M.abscessus_ATCC_199 VALAEGMQTSFWRLGGADATAQFTWYSVDLPPVMELRNQLLPNDERIVKL
MUL_4852|M.ulcerans_Agy99 VALAEGLQTSFWRLD----NGELNWLSVDLAPIVRLREQLLPACDRLRYC
MAV_2991|M.avium_104 LHLGCGLDGRAFRVS---VPPSLSWFDVDQPSVIGLRRRLYDDTENYRMI
: *. *:: :*:. : * :* .:: :* :* .
Mb1184c|M.bovis_AF2122/97 AQSALDYSWMDSVDPAGGVFITAEGLLMYLQPEQALGLIAQCAQTFPGGQ
Rv1153c|M.tuberculosis_H37Rv AQSALDYSWMDSVDPAGGVFITAEGLLMYLQPEQALGLIAQCAQTFPGGQ
MMAR_4300|M.marinum_M AQSALDYGWMDSVDTSGGVFITAEGLLMYLEPDQALDLIAQCAKRFPGAQ
Mflv_5259|M.gilvum_PYR-GCK AQSALDYSWMDAVDTTHGVFITAEGLLMYLQPEESMGLITECAARFPGAQ
Mvan_0979|M.vanbaalenii_PYR-1 AQSALDYSWMDAVDTTDGVFITAEGLLMYLQPDEAMDLITACASRFPGGQ
MSMEG_5173|M.smegmatis_MC2_155 AQSALDYSWMDQVDDSEGVFITAEGLLMYLQPEESMGLIKECARRFPGGQ
TH_0460|M.thermoresistible__bu AQSALDYSWMDRIDTSEGVFITAEGLLMYLQPDEAMGLIRECARRFPGGQ
MAB_1295c|M.abscessus_ATCC_199 AQSALDLSWMDQVDASGGAFITAEGLLMYLQPEESLGLIEACAKRFPGGQ
MUL_4852|M.ulcerans_Agy99 AQSAFDYSWMEQVDDTNGVLITAEGLFQYLRRDVVFELIAACAKRVPHGQ
MAV_2991|M.avium_104 GSSVTELQWLDEVPAGRPTLMVAEGLLMYLREDEVRRLLQRLIDRFPGGE
..*. : *:: : .::.****: **. : *: .* .:
Mb1184c|M.bovis_AF2122/97 MLFDLPPRWFAGWSR-LGLRTSLRYKVPRMPFSMSVAQAADLVNKVPGVV
Rv1153c|M.tuberculosis_H37Rv MLFDLPPRWFAGWSR-LGLRTSLRYKVPRMPFSMSVAQAADLVNKVPGVV
MMAR_4300|M.marinum_M MLFDLPPRWFSLFTR-LGMRTSIRYKIPPMPFSLSVAQAADLVNTIPGIR
Mflv_5259|M.gilvum_PYR-GCK MIFDLPPVMVKKFAP-KGVRSSSRYRVPPMPFSLSAAELADLVHTVPGVR
Mvan_0979|M.vanbaalenii_PYR-1 MIFDLPPTMVKKIAP-KGMRSSARYRVPPMPFSLSPAQLAELVHTVPGVT
MSMEG_5173|M.smegmatis_MC2_155 MIFDLPPSWFAAWAR-KGMRTSRRYRVPPMPFSLSPAEVADLVNTVPGVR
TH_0460|M.thermoresistible__bu MMFDLPPSFFAWLTR-RGFRTSLRYKVPPMPFTLSPEQAADLVNTVPGVQ
MAB_1295c|M.abscessus_ATCC_199 MMFDSIPHWFSRRTL-QGFKLSDRYVAPPMPFALTPDEGEALIS-IPGVV
MUL_4852|M.ulcerans_Agy99 LVFDSIPWLLSVYSRRRGFKLSEHYTAPPMPFWFT-ADHYDELRAIPGVR
MAV_2991|M.avium_104 MHFDTLSALAPLLSK----------VFTRGIITWGIRDARRIADWNPRLR
: ** . : . : : * :
Mb1184c|M.bovis_AF2122/97 AVRDLRVPPGRGLWVNMALSTVYRLPVFDPLRPCLTLLEFSRPARG--
Rv1153c|M.tuberculosis_H37Rv AVRDLRVPPGRGLWVNMALSTVYRLPVFDPLRPCLTLLEFSRPARG--
MMAR_4300|M.marinum_M AVRDVQLPAGRGLMFNAALSTVYRLPALDSLRPCLTLLEFG-------
Mflv_5259|M.gilvum_PYR-GCK AVHDLPMPQGRGFFFEKVFPAFWGLKATKNYRGAYTLLEFG-------
Mvan_0979|M.vanbaalenii_PYR-1 AVHDLPMPRGRGFLFERVFPAFWQFKPTRNYRGAYTLLEFG-------
MSMEG_5173|M.smegmatis_MC2_155 VVHDLPFPPARGKFMRTVVWGVQRLPLFDPIRPVMALLEFG-------
TH_0460|M.thermoresistible__bu AVHDVPIPRGRGVLVNTLIWAAQRTPLFDNVRGTYTLLEFGPPNSAST
MAB_1295c|M.abscessus_ATCC_199 TAIDIPLHRGRGIWKFVNSKRLDRG-FLRRTRPSMTLLQFG-------
MUL_4852|M.ulcerans_Agy99 AVRELPAPAGRGRFLRWALPVAYRLPGLGRLRAPVTLVEFG-------
MAV_2991|M.avium_104 FLEQSPALAGYQRIPSTVVRSIYRLTWLTGGRGYDVLNRFEY------
: . * .* .*