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M. gilvum PYR-GCK Mflv_5259 (-)

annotation: O-methyltransferase domain-containing protein
coordinates: 5605667 - 5606470
length: 267

LAGVSETALLTLNGRAYQARHPNAILDDPMAIRVVDSIDFDFDKFGRRKGQEMALRSLAFDRAATAYLAK
HPKATVVALAEGLQTSFWRLDAALPTAEFRWLTVDFEPIIELRRRLLPESARITTLAQSALDYSWMDAVD
TTHGVFITAEGLLMYLQPEESMGLITECAARFPGAQMIFDLPPVMVKKFAPKGVRSSSRYRVPPMPFSLS
AAELADLVHTVPGVRAVHDLPMPQGRGFFFEKVFPAFWGLKATKNYRGAYTLLEFG*

Operon Prediction Model: Genebank

Paralogs

species id gene e-value identity (len) annotation
M. gilvum PYR-GCK Mflv_5259 - - 100% (267) O-methyltransferase domain-containing protein
M. gilvum PYR-GCK Mflv_2136 - 8e-89 61.94% (268) O-methyltransferase domain-containing protein
M. gilvum PYR-GCK Mflv_3385 - 1e-19 30.77% (182) O-methyltransferase domain-containing protein

Closest Orthologs (e-value cutoff: 1e-4)

species id gene e-value identity (len) annotation
M. bovis AF2122 / 97 Mb1184c omt 8e-87 61.13% (265) O-methyltransferase
M. tuberculosis H37Rv Rv1153c omt 4e-88 61.89% (265) O-methyltransferase
M. leprae Br4923 - - - - -
M. abscessus ATCC 19977 MAB_1292c - 1e-71 52.43% (267) O-methyltransferase OMT
M. marinum M MMAR_2733 omt 1e-109 70.41% (267) O-methyltransferase Omt
M. avium 104 MAV_2991 - 3e-22 34.36% (195) tetracenomycin polyketide synthesis O-methyltransferase TcmP
M. smegmatis MC2 155 MSMEG_6661 - 1e-117 78.57% (266) O-methyltransferase, putative
M. thermoresistible (build 8) TH_0783 omt 1e-116 75.56% (266) PROBABLE O-METHYLTRANSFERASE OMT
M. ulcerans Agy99 MUL_3020 omt 1e-106 69.17% (266) O-methyltransferase Omt
M. vanbaalenii PYR-1 Mvan_0979 - 1e-133 84.59% (266) O-methyltransferase domain-containing protein

CLUSTAL 2.0.9 multiple sequence alignment


Mb1184c|M.bovis_AF2122/97           ---MSAHKPAKQRVALTGVSETALLTLNARAAEARRRDTIIDDPMAVALV
Rv1153c|M.tuberculosis_H37Rv        ---MSAHKPAKQRVALTGVSETALLTLNARAAEARRRDAIIDDPMAVALV
Mflv_5259|M.gilvum_PYR-GCK          --------------MLAGVSETALLTLNGRAYQARHPNAILDDPMAIRVV
Mvan_0979|M.vanbaalenii_PYR-1       ----MDQDGKIDAGALAGVSETALLTLNGRAYQARHPNAIIDDPMAIRLV
MSMEG_6661|M.smegmatis_MC2_155      MDRSEEPGGKIDASALTRVSETALLTLYGRAYQGRHQQAILNDPMAIRLV
TH_0783|M.thermoresistible__bu      --VHESNPDKLDASTLSGVSETALMTLYGRAEQARHPQPIIDDPMAVRLV
MMAR_2733|M.marinum_M               ---MGHSDNDANARMLGGVSETALLTLNGRAHQAAKPNPIIDDPMAIKLV
MUL_3020|M.ulcerans_Agy99           ---MGHSDNNVNAGMLGGVSETALLTLNGRAHQAAKPNPIIDDPMAIKLV
MAB_1292c|M.abscessus_ATCC_199      ----MAYMAAIDARHLDGVSETALITLNQRATEANRPDGVLEDPMAIVLR
MAV_2991|M.avium_104                --MTATEKVDFSSVAWGSVEWTNLVTLYLRACESRSRQPILGDTAAAEAV
                                                      *. * *:**  ** :.   : :: *. *    

Mb1184c|M.bovis_AF2122/97           ESIDFGFAKFGP------TGQGFALRARAFDMAAQHYLDQHPAATVVALA
Rv1153c|M.tuberculosis_H37Rv        ESIDFDFAKFGP------TGQGFALRARAFDMAAQHYLDQHPAATVVALA
Mflv_5259|M.gilvum_PYR-GCK          DSIDFDFDKFGRR-----KGQEMALRSLAFDRAATAYLAKHPKATVVALA
Mvan_0979|M.vanbaalenii_PYR-1       DAIDFDFDKFGRR-----KGQEMALRSLAFDRAATRYLSRHPAATVVALA
MSMEG_6661|M.smegmatis_MC2_155      DSIEFDFEKFGR------KGQEMALRSLAFDRAALAYLSAQPRATVVALA
TH_0783|M.thermoresistible__bu      DRIDFDFTKFGR------RGQEMALRSLAFDRAALRYLSDHPRATVVALA
MMAR_2733|M.marinum_M               ESIDFDFEKFGR------RGQEMALRSLAVDRCEIAYLTKHPGATVVALA
MUL_3020|M.ulcerans_Agy99           ESNDFDFEKFGR------RGQEMALRSLAVDRCEIAYLTKHPGATVVAHA
MAB_1292c|M.abscessus_ATCC_199      DSLDYDYHHFGR------THQGIALRALTFDTVSNEYLAEHPRATVVALA
MAV_2991|M.avium_104                DRIRYDFKRIHRMSLPASNQYLVALRAVQFDDWCAEFLARHPDAVVLHLG
                                    :   :.: ::            .***:  .*     :*  :* *.*:  .

Mb1184c|M.bovis_AF2122/97           EGLQTSFWRLDVAIPGGQFRWLTVDLPPIVDLRTRLLPSSPRVSVCAQSA
Rv1153c|M.tuberculosis_H37Rv        EGLQTSFWRLDVAIPGGQFRWLTVDLPPIVDLRTRLLPSSPRVSVCAQSA
Mflv_5259|M.gilvum_PYR-GCK          EGLQTSFWRLDAALPTAEFRWLTVDFEPIIELRRRLLPESARITTLAQSA
Mvan_0979|M.vanbaalenii_PYR-1       EGLQTSFWRLDAAIPDSRFRWVSIDLEPVIALRRRLLPDSPRITTLAQSA
MSMEG_6661|M.smegmatis_MC2_155      EGLQTTFWRLTDALPDAEFHWLTVDFQPIIDLRRRLLPADPRITCLAQSA
TH_0783|M.thermoresistible__bu      EGLQTTFWRVTDAIPDARFRWLTIDLPPIIELRERLLPAEPRIVTLAQSA
MMAR_2733|M.marinum_M               EGFQTGFWRVSNALPDTQFRWVSLDLEPVMELRRRLLPDSARVTNLAQSA
MUL_3020|M.ulcerans_Agy99           EGFQTGFWRVSNALPDTQFRWVSLDLEPVMELRRRLLPDSARVTNLAQSA
MAB_1292c|M.abscessus_ATCC_199      EGLQTSFWRID----NGELNWLSVDLEPIVRLRRQLLPPSDRVRYVAQSA
MAV_2991|M.avium_104                CGLDGRAFRVSVP---PSLSWFDVDQPSVIGLRRRLYDDTENYRMIGSSV
                                     *::   :*:        : *. :*  .:: ** :*     .    ..*.

Mb1184c|M.bovis_AF2122/97           LDYSWMDSVDPAGGVFITAEGLLMYLQPEQALGLIAQCAQTFPGGQMLFD
Rv1153c|M.tuberculosis_H37Rv        LDYSWMDSVDPAGGVFITAEGLLMYLQPEQALGLIAQCAQTFPGGQMLFD
Mflv_5259|M.gilvum_PYR-GCK          LDYSWMDAVDTTHGVFITAEGLLMYLQPEESMGLITECAARFPGAQMIFD
Mvan_0979|M.vanbaalenii_PYR-1       LDYSWMDAVDTTDGVFITAEGLLMYLQPDEAMDLITACASRFPGGQMIFD
MSMEG_6661|M.smegmatis_MC2_155      LDYSWMDQVDTGDGVFITAEGLLMYLEPEESMGLIKQCANRFAGGQMVFD
TH_0783|M.thermoresistible__bu      LDFSWMDRVDTDHGVLITAEGLLMYLQPDEAMTLIERCAARFPGGQMLFD
MMAR_2733|M.marinum_M               LDYTWMDKVDSRAGVFITAEGLLMYLQPNQAMELISQCAKRFAGGQMFFD
MUL_3020|M.ulcerans_Agy99           LDYTWMDKVDSCAAVFITAEGLLMYPQPNQAMELISQCAKRFAGGQMFFD
MAB_1292c|M.abscessus_ATCC_199      LDHSWMDQVDDSNGVLITAEGLFMYLERDVVFDLIAACAKRFPGGWMVFD
MAV_2991|M.avium_104                TELQWLDEVPAGRPTLMVAEGLLMYLREDEVRRLLQRLIDRFPGGEMHFD
                                     :  *:* *     .::.****:** . :    *:      *.*. * **

Mb1184c|M.bovis_AF2122/97           LPPRWFAGWSR-LGLRTSLRYKVPRMPFSMSVAQAADLVNKVPGVVAVRD
Rv1153c|M.tuberculosis_H37Rv        LPPRWFAGWSR-LGLRTSLRYKVPRMPFSMSVAQAADLVNKVPGVVAVRD
Mflv_5259|M.gilvum_PYR-GCK          LPPVMVKKFAP-KGVRSSSRYRVPPMPFSLSAAELADLVHTVPGVRAVHD
Mvan_0979|M.vanbaalenii_PYR-1       LPPTMVKKIAP-KGMRSSARYRVPPMPFSLSPAQLAELVHTVPGVTAVHD
MSMEG_6661|M.smegmatis_MC2_155      LPPVVVKKFAK-KGLRSSKRYRVPPMPFSLTPNQLQDLARTVPGIRAVHD
TH_0783|M.thermoresistible__bu      LPPVLLKKLAP-KGLRASRRYRVPPMPFSLSPAQLARLADTVPGVRAVHD
MMAR_2733|M.marinum_M               LPPTIVKRVAP-KGMRASRRYRVPPMPFSLSVNQLARLVDSVPGIRAVHD
MUL_3020|M.ulcerans_Agy99           LPPTIVKRVAP-KGMRASRRYRVPPMPFSLSVNQLARLVDTVPGIRAVHD
MAB_1292c|M.abscessus_ATCC_199      TIPWLMSVYSRRRGWRLSEHYTVPPMPFSFTAHQYGQLR-ALDGVSAVRE
MAV_2991|M.avium_104                TLSALAPLLSK----------VFTRGIITWGIRDARRIADWNPRLRFLEQ
                                      .      :            ..   ::    :   :      :  :.:

Mb1184c|M.bovis_AF2122/97           LRVPPGRGLWVNMALSTVYRLPVFDPLRPCLTLLEFSRPARG
Rv1153c|M.tuberculosis_H37Rv        LRVPPGRGLWVNMALSTVYRLPVFDPLRPCLTLLEFSRPARG
Mflv_5259|M.gilvum_PYR-GCK          LPMPQGRGFFFEKVFPAFWGLKATKNYRGAYTLLEFG-----
Mvan_0979|M.vanbaalenii_PYR-1       LPMPRGRGFLFERVFPAFWQFKPTRNYRGAYTLLEFG-----
MSMEG_6661|M.smegmatis_MC2_155      LPMPAGRGFLFEKVFPAFWQFKPTKQIRGAYTLLELG-----
TH_0783|M.thermoresistible__bu      LPMPEGRGFFFRAVFPRFWQARPTRQWRGAYTLLEFG-----
MMAR_2733|M.marinum_M               VPMPEGRGLFFKTLYPALWRFPPIKPFRGAYVLLEFG-----
MUL_3020|M.ulcerans_Agy99           VPMPEGRGLFFRTLYPALWRFPPIKPFRGAYVLLEFD-----
MAB_1292c|M.abscessus_ATCC_199      VRMPAGRGTFLKLATPLFYNLPLSDRIRPAMTVVEFG-----
MAV_2991|M.avium_104                SPALAGYQRIPSTVVRSIYRLTWLTGGRGYDVLNRFEY----
                                         *           .:        *   .: .:

species	id	gene	e-value	identity (len)	annotation
M. gilvum PYR-GCK	Mflv_5259	-	-	100% (267)	O-methyltransferase domain-containing protein
M. gilvum PYR-GCK	Mflv_2136	-	8e-89	61.94% (268)	O-methyltransferase domain-containing protein
M. gilvum PYR-GCK	Mflv_3385	-	1e-19	30.77% (182)	O-methyltransferase domain-containing protein