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SGIDVRHLDGVSETALLTLHQRATEAARTDGILDDPMAISLHASVDYDFAHFGRTHQATALRALIFDKAT REYLDYHPCATVVALAEGLQTSFWRVDNGRLTWLSVDLEPIVRLRQRLLPRSERLSHCAQSALDYSWMDR VDDSAGVLITAEGLFQYLERDLVFDLISVCAQRFPGGRLIFDSVPKFLSTHSQRGIRLSEQYVVPPMPFS FTANQYDELRAIPGIRSVRELRMPAGRGKVLRWAAPLLYALPGLDRWRAPHTVVEFG*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_0668c | - | - | 100% (268) | O-methyltransferase OmT |
| M. abscessus ATCC 19977 | MAB_1292c | - | e-106 | 69.89% (269) | O-methyltransferase OMT |
| M. abscessus ATCC 19977 | MAB_1295c | - | 7e-65 | 46.97% (264) | O-methyltransferase OMT |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1184c | omt | 5e-75 | 55.68% (264) | O-methyltransferase |
| M. gilvum PYR-GCK | Mflv_5259 | - | 8e-70 | 51.88% (266) | O-methyltransferase domain-containing protein |
| M. tuberculosis H37Rv | Rv1153c | omt | 5e-76 | 56.06% (264) | O-methyltransferase |
| M. leprae Br4923 | - | - | - | - | - |
| M. marinum M | MMAR_0262 | omt_1 | 1e-111 | 71.75% (269) | O-methyltransferase Omt_1 |
| M. avium 104 | MAV_2991 | - | 4e-20 | 34.81% (181) | tetracenomycin polyketide synthesis O-methyltransferase TcmP |
| M. smegmatis MC2 155 | MSMEG_5173 | - | 2e-72 | 53.38% (266) | O-methyltransferase, putative |
| M. thermoresistible (build 8) | TH_0783 | omt | 1e-71 | 51.11% (270) | PROBABLE O-METHYLTRANSFERASE OMT |
| M. ulcerans Agy99 | MUL_4852 | omt_1 | 1e-109 | 70.26% (269) | O-methyltransferase Omt_1 |
| M. vanbaalenii PYR-1 | Mvan_0979 | - | 3e-72 | 52.03% (271) | O-methyltransferase domain-containing protein |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_0262|M.marinum_M -----MPVIDARHLDGISETALLTLHQRATEAARPDAIIDDPMAIALRND
MUL_4852|M.ulcerans_Agy99 -----MPVIDARHLDDISETALLTLHQRATEAARPDAIIDDPMAIALRND
MAB_0668c|M.abscessus_ATCC_199 -----MSGIDVRHLDGVSETALLTLHQRATEAARTDGILDDPMAISLHAS
Mb1184c|M.bovis_AF2122/97 -MSAHKPAKQRVALTGVSETALLTLNARAAEARRRDTIIDDPMAVALVES
Rv1153c|M.tuberculosis_H37Rv -MSAHKPAKQRVALTGVSETALLTLNARAAEARRRDAIIDDPMAVALVES
MSMEG_5173|M.smegmatis_MC2_155 -MTTDATARTRVSLTGVSETALLTLQVRANEARRPDGLIKDPMAVQLVDS
Mflv_5259|M.gilvum_PYR-GCK ------------MLAGVSETALLTLNGRAYQARHPNAILDDPMAIRVVDS
Mvan_0979|M.vanbaalenii_PYR-1 --MDQDGKIDAGALAGVSETALLTLNGRAYQARHPNAIIDDPMAIRLVDA
TH_0783|M.thermoresistible__bu VHESNPDKLDASTLSGVSETALMTLYGRAEQARHPQPIIDDPMAVRLVDR
MAV_2991|M.avium_104 MTATEKVDFSSVAWGSVEWTNLVTLYLRACESRSRQPILGDTAAAEAVDR
.:. * *:** ** :: : :: *. *
MMAR_0262|M.marinum_M IDYPYHHFGRTH------QATALRALAFDNSTRDFLRTHPGATVVALAEG
MUL_4852|M.ulcerans_Agy99 IDYPYHHFGRTH------QATALRALAFDNSTRDFLQTRPGATVVALAEG
MAB_0668c|M.abscessus_ATCC_199 VDYDFAHFGRTH------QATALRALIFDKATREYLDYHPCATVVALAEG
Mb1184c|M.bovis_AF2122/97 IDFGFAKFGPTG------QGFALRARAFDMAAQHYLDQHPAATVVALAEG
Rv1153c|M.tuberculosis_H37Rv IDFDFAKFGPTG------QGFALRARAFDMAAQHYLDQHPAATVVALAEG
MSMEG_5173|M.smegmatis_MC2_155 IDFDFAKFGHSHR-----QDMALRSLIFDRATSDYLRDHPKATVVALAEG
Mflv_5259|M.gilvum_PYR-GCK IDFDFDKFGRRKG-----QEMALRSLAFDRAATAYLAKHPKATVVALAEG
Mvan_0979|M.vanbaalenii_PYR-1 IDFDFDKFGRRKG-----QEMALRSLAFDRAATRYLSRHPAATVVALAEG
TH_0783|M.thermoresistible__bu IDFDFTKFGRR-G-----QEMALRSLAFDRAALRYLSDHPRATVVALAEG
MAV_2991|M.avium_104 IRYDFKRIHRMSLPASNQYLVALRAVQFDDWCAEFLARHPDAVVLHLGCG
: : : :: ***: ** :* :* *.*: *. *
MMAR_0262|M.marinum_M LQTSFWRLD----NGELNWLSVDLAPIVRLREQLLPACDRLRYCAQSAFD
MUL_4852|M.ulcerans_Agy99 LQTSFWRLD----NGELNWLSVDLAPIVRLREQLLPACDRLRYCAQSAFD
MAB_0668c|M.abscessus_ATCC_199 LQTSFWRVD----NGRLTWLSVDLEPIVRLRQRLLPRSERLSHCAQSALD
Mb1184c|M.bovis_AF2122/97 LQTSFWRLDVAIPGGQFRWLTVDLPPIVDLRTRLLPSSPRVSVCAQSALD
Rv1153c|M.tuberculosis_H37Rv LQTSFWRLDVAIPGGQFRWLTVDLPPIVDLRTRLLPSSPRVSVCAQSALD
MSMEG_5173|M.smegmatis_MC2_155 LQTSFYRLNEAGVGDQFCWLTVDLPPMVEIRNKLLPPSDRVRTCAQSALD
Mflv_5259|M.gilvum_PYR-GCK LQTSFWRLDAALPTAEFRWLTVDFEPIIELRRRLLPESARITTLAQSALD
Mvan_0979|M.vanbaalenii_PYR-1 LQTSFWRLDAAIPDSRFRWVSIDLEPVIALRRRLLPDSPRITTLAQSALD
TH_0783|M.thermoresistible__bu LQTTFWRVTDAIPDARFRWLTIDLPPIIELRERLLPAEPRIVTLAQSALD
MAV_2991|M.avium_104 LDGRAFRVS---VPPSLSWFDVDQPSVIGLRRRLYDDTENYRMIGSSVTE
*: :*: : *. :* .:: :* :* . ..*. :
MMAR_0262|M.marinum_M YSWMEQVDDTNGVLITAEGLFQYLRRDVVFELIAACAKRFPHGQLVFDSI
MUL_4852|M.ulcerans_Agy99 YSWMEQVDDTNGVLITAEGLFQYLRRDVVFELIAACAKRVPHGQLVFDSI
MAB_0668c|M.abscessus_ATCC_199 YSWMDRVDDSAGVLITAEGLFQYLERDLVFDLISVCAQRFPGGRLIFDSV
Mb1184c|M.bovis_AF2122/97 YSWMDSVDPAGGVFITAEGLLMYLQPEQALGLIAQCAQTFPGGQMLFDLP
Rv1153c|M.tuberculosis_H37Rv YSWMDSVDPAGGVFITAEGLLMYLQPEQALGLIAQCAQTFPGGQMLFDLP
MSMEG_5173|M.smegmatis_MC2_155 YSWMDQVDDSEGVFITAEGLLMYLQPEESMGLIKECARRFPGGQMIFDLP
Mflv_5259|M.gilvum_PYR-GCK YSWMDAVDTTHGVFITAEGLLMYLQPEESMGLITECAARFPGAQMIFDLP
Mvan_0979|M.vanbaalenii_PYR-1 YSWMDAVDTTDGVFITAEGLLMYLQPDEAMDLITACASRFPGGQMIFDLP
TH_0783|M.thermoresistible__bu FSWMDRVDTDHGVLITAEGLLMYLQPDEAMTLIERCAARFPGGQMLFDLP
MAV_2991|M.avium_104 LQWLDEVPAGRPTLMVAEGLLMYLREDEVRRLLQRLIDRFPGGEMHFDTL
.*:: * .::.****: **. : *: .* ..: **
MMAR_0262|M.marinum_M PWLLSVYSRRRGFRLSEHYTAPPMPFWFTADHYDELR-AIPGVRAVRELP
MUL_4852|M.ulcerans_Agy99 PWLLSVYSRRRGFKLSEHYTAPPMPFWFTADHYDELR-AIPGVRAVRELP
MAB_0668c|M.abscessus_ATCC_199 PKFLSTHSQR-GIRLSEQYVVPPMPFSFTANQYDELR-AIPGIRSVRELR
Mb1184c|M.bovis_AF2122/97 PRWFAGWSRL-GLRTSLRYKVPRMPFSMSVAQAADLVNKVPGVVAVRDLR
Rv1153c|M.tuberculosis_H37Rv PRWFAGWSRL-GLRTSLRYKVPRMPFSMSVAQAADLVNKVPGVVAVRDLR
MSMEG_5173|M.smegmatis_MC2_155 PSWFAAWARK-GMRTSRRYRVPPMPFSLSPAEVADLVNTVPGVRVVHDLP
Mflv_5259|M.gilvum_PYR-GCK PVMVKKFAPK-GVRSSSRYRVPPMPFSLSAAELADLVHTVPGVRAVHDLP
Mvan_0979|M.vanbaalenii_PYR-1 PTMVKKIAPK-GMRSSARYRVPPMPFSLSPAQLAELVHTVPGVTAVHDLP
TH_0783|M.thermoresistible__bu PVLLKKLAPK-GLRASRRYRVPPMPFSLSPAQLARLADTVPGVRAVHDLP
MAV_2991|M.avium_104 SALAPLLSKV----------FTRGIITWGIRDARRIADWNPRLRFLEQSP
. : . : . : * : :.:
MMAR_0262|M.marinum_M APAGRGRFLRWALPVAYRLPGLGRLRAPVTLVEFG-----
MUL_4852|M.ulcerans_Agy99 APAGRGRFLRWALPVAYRLPGLGRLRAPVTLVEFG-----
MAB_0668c|M.abscessus_ATCC_199 MPAGRGKVLRWAAPLLYALPGLDRWRAPHTVVEFG-----
Mb1184c|M.bovis_AF2122/97 VPPGRGLWVNMALSTVYRLPVFDPLRPCLTLLEFSRPARG
Rv1153c|M.tuberculosis_H37Rv VPPGRGLWVNMALSTVYRLPVFDPLRPCLTLLEFSRPARG
MSMEG_5173|M.smegmatis_MC2_155 FPPARGKFMRTVVWGVQRLPLFDPIRPVMALLEFG-----
Mflv_5259|M.gilvum_PYR-GCK MPQGRGFFFEKVFPAFWGLKATKNYRGAYTLLEFG-----
Mvan_0979|M.vanbaalenii_PYR-1 MPRGRGFLFERVFPAFWQFKPTRNYRGAYTLLEFG-----
TH_0783|M.thermoresistible__bu MPEGRGFFFRAVFPRFWQARPTRQWRGAYTLLEFG-----
MAV_2991|M.avium_104 ALAGYQRIPSTVVRSIYRLTWLTGGRGYDVLNRFEY----
. . * .: .*