For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
aa seq not available
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. thermoresistible (build 8) | TH_0460 | omt | - | 100% (284) | PROBABLE O-METHYLTRANSFERASE OMT |
M. thermoresistible (build 8) | TH_0783 | omt | 1e-92 | 64.31% (269) | PROBABLE O-METHYLTRANSFERASE OMT |
M. thermoresistible (build 8) | TH_4502 | - | 6e-05 | 29.41% (187) | PUTATIVE methyltransferase |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb1184c | omt | 4e-96 | 66.04% (268) | O-methyltransferase |
M. gilvum PYR-GCK | Mflv_2136 | - | 1e-109 | 72.49% (269) | O-methyltransferase domain-containing protein |
M. tuberculosis H37Rv | Rv1153c | omt | 4e-97 | 66.42% (268) | O-methyltransferase |
M. leprae Br4923 | MLBr_02640 | - | 3e-05 | 27.59% (203) | hypothetical protein MLBr_02640 |
M. abscessus ATCC 19977 | MAB_1295c | - | 3e-77 | 53.93% (280) | O-methyltransferase OMT |
M. marinum M | MMAR_4300 | omt_2 | 1e-101 | 66.91% (269) | O-methyltransferase Omt_2 |
M. avium 104 | MAV_2991 | - | 1e-24 | 36.81% (182) | tetracenomycin polyketide synthesis O-methyltransferase TcmP |
M. smegmatis MC2 155 | MSMEG_5173 | - | 1e-112 | 73.31% (266) | O-methyltransferase, putative |
M. ulcerans Agy99 | MUL_3020 | omt | 5e-84 | 60.38% (265) | O-methyltransferase Omt |
M. vanbaalenii PYR-1 | Mvan_4568 | - | 1e-113 | 68.98% (303) | O-methyltransferase domain-containing protein |
CLUSTAL 2.0.9 multiple sequence alignment Mflv_2136|M.gilvum_PYR-GCK --------MSPTDKHSA-DLTGVSETALMTLLVRATEARRPDSLIDDPMA Mvan_4568|M.vanbaalenii_PYR-1 --------MNHTGKHTATDVTGVSETALLTLLVRATEARRPDSLIDDPMA TH_0460|M.thermoresistible__bu ---------VSSGPLAKPELTGVSETALLTLLVRATEARRPDGIIDDPMA MSMEG_5173|M.smegmatis_MC2_155 -------MTTDATARTRVSLTGVSETALLTLQVRANEARRPDGLIKDPMA Mb1184c|M.bovis_AF2122/97 ------MS-AHKPAKQRVALTGVSETALLTLNARAAEARRRDTIIDDPMA Rv1153c|M.tuberculosis_H37Rv ------MS-AHKPAKQRVALTGVSETALLTLNARAAEARRRDAIIDDPMA MMAR_4300|M.marinum_M ------MTPADEFAQQKVALTGVSETALLTLNARAAEARRRDPIIEDPMA MUL_3020|M.ulcerans_Agy99 -------MGHSDNNVNAGMLGGVSETALLTLNGRAHQAAKPNPIIDDPMA MAB_1295c|M.abscessus_ATCC_199 MTESDALRPSGSSRISGDSLEGVSATTLWTLHNRGTEAKRPDSVIRDPLA MAV_2991|M.avium_104 ------MTATEKVDFSSVAWGSVEWTNLVTLYLRACESRSRQPILGDTAA MLBr_02640|M.leprae_Br4923 ---------MRTHDDTWDIKTSVGTTAVMVAAARAAETDRPDALIRDPYA .* * : . *. :: : :: *. * Mflv_2136|M.gilvum_PYR-GCK VKLVDSL--------DFDRAKFG-----FVRRQDMAVRALVFDKWTRRYL Mvan_4568|M.vanbaalenii_PYR-1 IHLVDSI--------DFDFAKFG-----YVRRQDMSLRALAFDKQTRRYL TH_0460|M.thermoresistible__bu VRLVDSI--------DFDFAKFG-----PSRRQDMALRAKAFDTATRRYL MSMEG_5173|M.smegmatis_MC2_155 VQLVDSI--------DFDFAKFG-----HSHRQDMALRSLIFDRATSDYL Mb1184c|M.bovis_AF2122/97 VALVESI--------DFGFAKFG-----PTG-QGFALRARAFDMAAQHYL Rv1153c|M.tuberculosis_H37Rv VALVESI--------DFDFAKFG-----PTG-QGFALRARAFDMAAQHYL MMAR_4300|M.marinum_M VRLVDSI--------DFDFAKFG-----PTR-QDIALRALAFDTRALAYL MUL_3020|M.ulcerans_Agy99 IKLVESN--------DFDFEKFG-----RRG-QEMALRSLAVDRCEIAYL MAB_1295c|M.abscessus_ATCC_199 AELFDAI--------EYDYRKFG-----RPS-QTHALRALAFDTQARVYL MAV_2991|M.avium_104 AEAVDRI--------RYDFKRIHRMSLPASNQYLVALRAVQFDDWCAEFL MLBr_02640|M.leprae_Br4923 KLLVTNTGAGALWEAMLDPSMVAKVEAIDAEAAAMVEHMRSYQAVRTNFF . . . : : :: Mflv_2136|M.gilvum_PYR-GCK VDHPRATVVA-------LAEGLQTSFYRLDSGPESVGHDFRWLTVDLPPM Mvan_4568|M.vanbaalenii_PYR-1 RDHPKATVVA-------LAEGLQTSFYRLDAQGPDVGHDFRWLTVDLPPM TH_0460|M.thermoresistible__bu RAHPKATVVA-------LAEGLQTSFFRLN--AADVGDEFRWVTVDLAPV MSMEG_5173|M.smegmatis_MC2_155 RDHPKATVVA-------LAEGLQTSFYRLN--EAGVGDQFCWLTVDLPPM Mb1184c|M.bovis_AF2122/97 DQHPAATVVA-------LAEGLQTSFWRLD--VAIPGGQFRWLTVDLPPI Rv1153c|M.tuberculosis_H37Rv DQHPAATVVA-------LAEGLQTSFWRLD--VAIPGGQFRWLTVDLPPI MMAR_4300|M.marinum_M NKHPSATVVA-------LAEGLQTSFWRLD--SALPGKKFRWLTVDLPPI MUL_3020|M.ulcerans_Agy99 TKHPGATVVA-------HAEGFQTGFWRVS--NALPDTQFRWVSLDLEPV MAB_1295c|M.abscessus_ATCC_199 ATHPRAAIVA-------LAEGMQTSFWRLG--GADATAQFTWYSVDLPPV MAV_2991|M.avium_104 ARHPDAVVLH-------LGCGLDGRAFRVS-----VPPSLSWFDVDQPSV MLBr_02640|M.leprae_Br4923 DTYFNNAVIDGIRQFVILASGLDSRAYRLD-----WPTGTTVYEIDQPKV : .:: . *:: :*:. :* : Mflv_2136|M.gilvum_PYR-GCK IDLRTKLLPPSDRVRTLAQS----ALDFSWMDQVDTSEG----------- Mvan_4568|M.vanbaalenii_PYR-1 IELRRKLLPASDRVQMLAQS----ALDFSWMDRVPTDDGDVNQAGDDGDV TH_0460|M.thermoresistible__bu IELRRQLLPADDRVTMLAQS----ALDYSWMDRIDTSEG----------- MSMEG_5173|M.smegmatis_MC2_155 VEIRNKLLPPSDRVRTCAQS----ALDYSWMDQVDDSEG----------- Mb1184c|M.bovis_AF2122/97 VDLRTRLLPSSPRVSVCAQS----ALDYSWMDSVDPAGG----------- Rv1153c|M.tuberculosis_H37Rv VDLRTRLLPSSPRVSVCAQS----ALDYSWMDSVDPAGG----------- MMAR_4300|M.marinum_M IDIRKRLLPNSPRVSVCAQS----ALDYGWMDSVDTSGG----------- MUL_3020|M.ulcerans_Agy99 MELRRRLLPDSARVTNLAQS----ALDYTWMDKVDSCAA----------- MAB_1295c|M.abscessus_ATCC_199 MELRNQLLPNDERIVKLAQS----ALDLSWMDQVDASGG----------- MAV_2991|M.avium_104 IGLRRRLYDDTENYRMIGSS----VTELQWLDEVPAGRP----------- MLBr_02640|M.leprae_Br4923 LAYKSTTLAEHGVTPTADRREVPIDLRQDWPPALRSAGFDPSAR------ : : * : Mflv_2136|M.gilvum_PYR-GCK ----------------VFITAEGLLMYLQPAEAMSLITECAARFPGGQMI Mvan_4568|M.vanbaalenii_PYR-1 NQAGDDGDVDQAGADGVFITAEGLLMYLQPEESMALITECAARFPGGRMM TH_0460|M.thermoresistible__bu ----------------VFITAEGLLMYLQPDEAMGLIRECARRFPGGQMM MSMEG_5173|M.smegmatis_MC2_155 ----------------VFITAEGLLMYLQPEESMGLIKECARRFPGGQMI Mb1184c|M.bovis_AF2122/97 ----------------VFITAEGLLMYLQPEQALGLIAQCAQTFPGGQML Rv1153c|M.tuberculosis_H37Rv ----------------VFITAEGLLMYLQPEQALGLIAQCAQTFPGGQML MMAR_4300|M.marinum_M ----------------VFITAEGLLMYLEPDQALDLIAQCAKRFPGAQML MUL_3020|M.ulcerans_Agy99 ----------------VFITAEGLLMYPQPNQAMELISQCAKRFAGGQMF MAB_1295c|M.abscessus_ATCC_199 ----------------AFITAEGLLMYLQPEESLGLIEACAKRFPGGQMM MAV_2991|M.avium_104 ----------------TLMVAEGLLMYLREDEVRRLLQRLIDRFPGGEMH MLBr_02640|M.leprae_Br4923 ----------------TAWLAEGLLMYLPATAQDGLFTEIGGLSAVGSRI . ******* *: . . Mflv_2136|M.gilvum_PYR-GCK FDLPPSAFAFLVGRGVRASLRYRVPPMPFSLTIAEAADLVNTVPGVRAVH Mvan_4568|M.vanbaalenii_PYR-1 FDLPPSAFAPLVRRGFRASLRYRVPPMPFTLSPAEAADLVNTVPGVRAVH TH_0460|M.thermoresistible__bu FDLPPSFFAWLTRRGFRTSLRYKVPPMPFTLSPEQAADLVNTVPGVQAVH MSMEG_5173|M.smegmatis_MC2_155 FDLPPSWFAAWARKGMRTSRRYRVPPMPFSLSPAEVADLVNTVPGVRVVH Mb1184c|M.bovis_AF2122/97 FDLPPRWFAGWSRLGLRTSLRYKVPRMPFSMSVAQAADLVNKVPGVVAVR Rv1153c|M.tuberculosis_H37Rv FDLPPRWFAGWSRLGLRTSLRYKVPRMPFSMSVAQAADLVNKVPGVVAVR MMAR_4300|M.marinum_M FDLPPRWFSLFTRLGMRTSIRYKIPPMPFSLSVAQAADLVNTIPGIRAVR MUL_3020|M.ulcerans_Agy99 FDLPPTIVKRVAPKGMRASRRYRVPPMPFSLSVNQLARLVDTVPGIRAVH MAB_1295c|M.abscessus_ATCC_199 FDSIPHWFSRRTLQGFKLSDRYVAPPMPFALTPDEGEALIS-IPGVVTAI MAV_2991|M.avium_104 FDTLSALAPLLSKVFTRGIITWGIR---------DARRIADWNPRLRFLE MLBr_02640|M.leprae_Br4923 AVETSPLHGDEWREQMQLRFRRVSDALGFEQA-VDVQELIYHDENRAVVA . : : : Mflv_2136|M.gilvum_PYR-GCK DLPAEHARGRLINALLWTAQRVPLLDPIRPMF----TLLEFG------- Mvan_4568|M.vanbaalenii_PYR-1 DVPAEHARGRILNALLWTAQRVPLLDPVRPMF----TLLEFG------- TH_0460|M.thermoresistible__bu DVPIPRGRGVLVNTLIWAAQRTPLFDNVRGTY----TLLEFGPPNSAST MSMEG_5173|M.smegmatis_MC2_155 DLPFPPARGKFMRTVVWGVQRLPLFDPIRPVM----ALLEFG------- Mb1184c|M.bovis_AF2122/97 DLRVPPGRGLWVNMALSTVYRLPVFDPLRPCL----TLLEFSRPARG-- Rv1153c|M.tuberculosis_H37Rv DLRVPPGRGLWVNMALSTVYRLPVFDPLRPCL----TLLEFSRPARG-- MMAR_4300|M.marinum_M DVQLPAGRGLMFNAALSTVYRLPALDSLRPCL----TLLEFG------- MUL_3020|M.ulcerans_Agy99 DVPMPEGRGLFFRTLYPALWRFPPIKPFRGAY----VLLEFD------- MAB_1295c|M.abscessus_ATCC_199 DIPLHRGRGIWKFVNSKRLDRG-FLRRTRPSM----TLLQFG------- MAV_2991|M.avium_104 QSPALAGYQRIPSTVVRSIYRLTWLTGGRGYD----VLNRFEY------ MLBr_02640|M.leprae_Br4923 DWLNRHGWRATAQSAPDEMRRVGRWGDGVPMADDKDAFAEFVTAHRL-- : . * .: .*