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M. thermoresistible (build 8) TH_0460 (omt)

annotation: PROBABLE O-METHYLTRANSFERASE OMT
coordinates: 990523 - 991374
length: 284

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_0460omt-100% (284)PROBABLE O-METHYLTRANSFERASE OMT
M. thermoresistible (build 8)TH_0783omt1e-9264.31% (269) PROBABLE O-METHYLTRANSFERASE OMT
M. thermoresistible (build 8)TH_4502-6e-0529.41% (187) PUTATIVE methyltransferase

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb1184comt4e-9666.04% (268) O-methyltransferase
M. gilvum PYR-GCKMflv_2136-1e-10972.49% (269) O-methyltransferase domain-containing protein
M. tuberculosis H37RvRv1153comt4e-9766.42% (268) O-methyltransferase
M. leprae Br4923MLBr_02640-3e-0527.59% (203) hypothetical protein MLBr_02640
M. abscessus ATCC 19977MAB_1295c-3e-7753.93% (280) O-methyltransferase OMT
M. marinum MMMAR_4300omt_21e-10166.91% (269) O-methyltransferase Omt_2
M. avium 104MAV_2991-1e-2436.81% (182) tetracenomycin polyketide synthesis O-methyltransferase TcmP
M. smegmatis MC2 155MSMEG_5173-1e-11273.31% (266) O-methyltransferase, putative
M. ulcerans Agy99MUL_3020omt5e-8460.38% (265) O-methyltransferase Omt
M. vanbaalenii PYR-1Mvan_4568-1e-11368.98% (303) O-methyltransferase domain-containing protein

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_2136|M.gilvum_PYR-GCK          --------MSPTDKHSA-DLTGVSETALMTLLVRATEARRPDSLIDDPMA
Mvan_4568|M.vanbaalenii_PYR-1       --------MNHTGKHTATDVTGVSETALLTLLVRATEARRPDSLIDDPMA
TH_0460|M.thermoresistible__bu      ---------VSSGPLAKPELTGVSETALLTLLVRATEARRPDGIIDDPMA
MSMEG_5173|M.smegmatis_MC2_155      -------MTTDATARTRVSLTGVSETALLTLQVRANEARRPDGLIKDPMA
Mb1184c|M.bovis_AF2122/97           ------MS-AHKPAKQRVALTGVSETALLTLNARAAEARRRDTIIDDPMA
Rv1153c|M.tuberculosis_H37Rv        ------MS-AHKPAKQRVALTGVSETALLTLNARAAEARRRDAIIDDPMA
MMAR_4300|M.marinum_M               ------MTPADEFAQQKVALTGVSETALLTLNARAAEARRRDPIIEDPMA
MUL_3020|M.ulcerans_Agy99           -------MGHSDNNVNAGMLGGVSETALLTLNGRAHQAAKPNPIIDDPMA
MAB_1295c|M.abscessus_ATCC_199      MTESDALRPSGSSRISGDSLEGVSATTLWTLHNRGTEAKRPDSVIRDPLA
MAV_2991|M.avium_104                ------MTATEKVDFSSVAWGSVEWTNLVTLYLRACESRSRQPILGDTAA
MLBr_02640|M.leprae_Br4923          ---------MRTHDDTWDIKTSVGTTAVMVAAARAAETDRPDALIRDPYA
                                                         .*  * : .   *. ::   : :: *. *

Mflv_2136|M.gilvum_PYR-GCK          VKLVDSL--------DFDRAKFG-----FVRRQDMAVRALVFDKWTRRYL
Mvan_4568|M.vanbaalenii_PYR-1       IHLVDSI--------DFDFAKFG-----YVRRQDMSLRALAFDKQTRRYL
TH_0460|M.thermoresistible__bu      VRLVDSI--------DFDFAKFG-----PSRRQDMALRAKAFDTATRRYL
MSMEG_5173|M.smegmatis_MC2_155      VQLVDSI--------DFDFAKFG-----HSHRQDMALRSLIFDRATSDYL
Mb1184c|M.bovis_AF2122/97           VALVESI--------DFGFAKFG-----PTG-QGFALRARAFDMAAQHYL
Rv1153c|M.tuberculosis_H37Rv        VALVESI--------DFDFAKFG-----PTG-QGFALRARAFDMAAQHYL
MMAR_4300|M.marinum_M               VRLVDSI--------DFDFAKFG-----PTR-QDIALRALAFDTRALAYL
MUL_3020|M.ulcerans_Agy99           IKLVESN--------DFDFEKFG-----RRG-QEMALRSLAVDRCEIAYL
MAB_1295c|M.abscessus_ATCC_199      AELFDAI--------EYDYRKFG-----RPS-QTHALRALAFDTQARVYL
MAV_2991|M.avium_104                AEAVDRI--------RYDFKRIHRMSLPASNQYLVALRAVQFDDWCAEFL
MLBr_02640|M.leprae_Br4923          KLLVTNTGAGALWEAMLDPSMVAKVEAIDAEAAAMVEHMRSYQAVRTNFF
                                       .             .   .               :    :     ::

Mflv_2136|M.gilvum_PYR-GCK          VDHPRATVVA-------LAEGLQTSFYRLDSGPESVGHDFRWLTVDLPPM
Mvan_4568|M.vanbaalenii_PYR-1       RDHPKATVVA-------LAEGLQTSFYRLDAQGPDVGHDFRWLTVDLPPM
TH_0460|M.thermoresistible__bu      RAHPKATVVA-------LAEGLQTSFFRLN--AADVGDEFRWVTVDLAPV
MSMEG_5173|M.smegmatis_MC2_155      RDHPKATVVA-------LAEGLQTSFYRLN--EAGVGDQFCWLTVDLPPM
Mb1184c|M.bovis_AF2122/97           DQHPAATVVA-------LAEGLQTSFWRLD--VAIPGGQFRWLTVDLPPI
Rv1153c|M.tuberculosis_H37Rv        DQHPAATVVA-------LAEGLQTSFWRLD--VAIPGGQFRWLTVDLPPI
MMAR_4300|M.marinum_M               NKHPSATVVA-------LAEGLQTSFWRLD--SALPGKKFRWLTVDLPPI
MUL_3020|M.ulcerans_Agy99           TKHPGATVVA-------HAEGFQTGFWRVS--NALPDTQFRWVSLDLEPV
MAB_1295c|M.abscessus_ATCC_199      ATHPRAAIVA-------LAEGMQTSFWRLG--GADATAQFTWYSVDLPPV
MAV_2991|M.avium_104                ARHPDAVVLH-------LGCGLDGRAFRVS-----VPPSLSWFDVDQPSV
MLBr_02640|M.leprae_Br4923          DTYFNNAVIDGIRQFVILASGLDSRAYRLD-----WPTGTTVYEIDQPKV
                                      :   .::         . *::   :*:.              :*   :

Mflv_2136|M.gilvum_PYR-GCK          IDLRTKLLPPSDRVRTLAQS----ALDFSWMDQVDTSEG-----------
Mvan_4568|M.vanbaalenii_PYR-1       IELRRKLLPASDRVQMLAQS----ALDFSWMDRVPTDDGDVNQAGDDGDV
TH_0460|M.thermoresistible__bu      IELRRQLLPADDRVTMLAQS----ALDYSWMDRIDTSEG-----------
MSMEG_5173|M.smegmatis_MC2_155      VEIRNKLLPPSDRVRTCAQS----ALDYSWMDQVDDSEG-----------
Mb1184c|M.bovis_AF2122/97           VDLRTRLLPSSPRVSVCAQS----ALDYSWMDSVDPAGG-----------
Rv1153c|M.tuberculosis_H37Rv        VDLRTRLLPSSPRVSVCAQS----ALDYSWMDSVDPAGG-----------
MMAR_4300|M.marinum_M               IDIRKRLLPNSPRVSVCAQS----ALDYGWMDSVDTSGG-----------
MUL_3020|M.ulcerans_Agy99           MELRRRLLPDSARVTNLAQS----ALDYTWMDKVDSCAA-----------
MAB_1295c|M.abscessus_ATCC_199      MELRNQLLPNDERIVKLAQS----ALDLSWMDQVDASGG-----------
MAV_2991|M.avium_104                IGLRRRLYDDTENYRMIGSS----VTELQWLDEVPAGRP-----------
MLBr_02640|M.leprae_Br4923          LAYKSTTLAEHGVTPTADRREVPIDLRQDWPPALRSAGFDPSAR------
                                    :  :                         *   :                

Mflv_2136|M.gilvum_PYR-GCK          ----------------VFITAEGLLMYLQPAEAMSLITECAARFPGGQMI
Mvan_4568|M.vanbaalenii_PYR-1       NQAGDDGDVDQAGADGVFITAEGLLMYLQPEESMALITECAARFPGGRMM
TH_0460|M.thermoresistible__bu      ----------------VFITAEGLLMYLQPDEAMGLIRECARRFPGGQMM
MSMEG_5173|M.smegmatis_MC2_155      ----------------VFITAEGLLMYLQPEESMGLIKECARRFPGGQMI
Mb1184c|M.bovis_AF2122/97           ----------------VFITAEGLLMYLQPEQALGLIAQCAQTFPGGQML
Rv1153c|M.tuberculosis_H37Rv        ----------------VFITAEGLLMYLQPEQALGLIAQCAQTFPGGQML
MMAR_4300|M.marinum_M               ----------------VFITAEGLLMYLEPDQALDLIAQCAKRFPGAQML
MUL_3020|M.ulcerans_Agy99           ----------------VFITAEGLLMYPQPNQAMELISQCAKRFAGGQMF
MAB_1295c|M.abscessus_ATCC_199      ----------------AFITAEGLLMYLQPEESLGLIEACAKRFPGGQMM
MAV_2991|M.avium_104                ----------------TLMVAEGLLMYLREDEVRRLLQRLIDRFPGGEMH
MLBr_02640|M.leprae_Br4923          ----------------TAWLAEGLLMYLPATAQDGLFTEIGGLSAVGSRI
                                                    .   *******        *:       . .   

Mflv_2136|M.gilvum_PYR-GCK          FDLPPSAFAFLVGRGVRASLRYRVPPMPFSLTIAEAADLVNTVPGVRAVH
Mvan_4568|M.vanbaalenii_PYR-1       FDLPPSAFAPLVRRGFRASLRYRVPPMPFTLSPAEAADLVNTVPGVRAVH
TH_0460|M.thermoresistible__bu      FDLPPSFFAWLTRRGFRTSLRYKVPPMPFTLSPEQAADLVNTVPGVQAVH
MSMEG_5173|M.smegmatis_MC2_155      FDLPPSWFAAWARKGMRTSRRYRVPPMPFSLSPAEVADLVNTVPGVRVVH
Mb1184c|M.bovis_AF2122/97           FDLPPRWFAGWSRLGLRTSLRYKVPRMPFSMSVAQAADLVNKVPGVVAVR
Rv1153c|M.tuberculosis_H37Rv        FDLPPRWFAGWSRLGLRTSLRYKVPRMPFSMSVAQAADLVNKVPGVVAVR
MMAR_4300|M.marinum_M               FDLPPRWFSLFTRLGMRTSIRYKIPPMPFSLSVAQAADLVNTIPGIRAVR
MUL_3020|M.ulcerans_Agy99           FDLPPTIVKRVAPKGMRASRRYRVPPMPFSLSVNQLARLVDTVPGIRAVH
MAB_1295c|M.abscessus_ATCC_199      FDSIPHWFSRRTLQGFKLSDRYVAPPMPFALTPDEGEALIS-IPGVVTAI
MAV_2991|M.avium_104                FDTLSALAPLLSKVFTRGIITWGIR---------DARRIADWNPRLRFLE
MLBr_02640|M.leprae_Br4923          AVETSPLHGDEWREQMQLRFRRVSDALGFEQA-VDVQELIYHDENRAVVA
                                        .           :                 :   :           

Mflv_2136|M.gilvum_PYR-GCK          DLPAEHARGRLINALLWTAQRVPLLDPIRPMF----TLLEFG-------
Mvan_4568|M.vanbaalenii_PYR-1       DVPAEHARGRILNALLWTAQRVPLLDPVRPMF----TLLEFG-------
TH_0460|M.thermoresistible__bu      DVPIPRGRGVLVNTLIWAAQRTPLFDNVRGTY----TLLEFGPPNSAST
MSMEG_5173|M.smegmatis_MC2_155      DLPFPPARGKFMRTVVWGVQRLPLFDPIRPVM----ALLEFG-------
Mb1184c|M.bovis_AF2122/97           DLRVPPGRGLWVNMALSTVYRLPVFDPLRPCL----TLLEFSRPARG--
Rv1153c|M.tuberculosis_H37Rv        DLRVPPGRGLWVNMALSTVYRLPVFDPLRPCL----TLLEFSRPARG--
MMAR_4300|M.marinum_M               DVQLPAGRGLMFNAALSTVYRLPALDSLRPCL----TLLEFG-------
MUL_3020|M.ulcerans_Agy99           DVPMPEGRGLFFRTLYPALWRFPPIKPFRGAY----VLLEFD-------
MAB_1295c|M.abscessus_ATCC_199      DIPLHRGRGIWKFVNSKRLDRG-FLRRTRPSM----TLLQFG-------
MAV_2991|M.avium_104                QSPALAGYQRIPSTVVRSIYRLTWLTGGRGYD----VLNRFEY------
MLBr_02640|M.leprae_Br4923          DWLNRHGWRATAQSAPDEMRRVGRWGDGVPMADDKDAFAEFVTAHRL--
                                    :     .             *               .: .*