For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
MTQTAPAAVAYSVNHAGVAAIVLDRPEASNALDRTMKTELLQALLAAGGDPAVRAVVMSAAGKNFCVGQD LAEHVEALRDDPAHAMDTVREHYNPVLEALDAIKVPVVVAINGACVGAGLGLALGADIRIAGQRAKFGTA FTGIGLAADSALSASLPRLIGASRATAMFLLGDTIDAPTAHTWGLVHEVVDEGSPADVANSVAGRLAGGP TAAFSEVKELLRRNAVAPLGDVLEREASAQQRLGASRDHSAAVEAFLAKDKPVFVGR
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_0905 | - | - | 100% (267) | putative enoyl-CoA hydratase/isomerase |
| M. abscessus ATCC 19977 | MAB_3281 | - | 4e-29 | 31.50% (254) | putative enoyl-CoA hydratase/isomerase |
| M. abscessus ATCC 19977 | MAB_0834 | - | 1e-28 | 33.20% (256) | putative enoyl-CoA hydratase/isomerase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1174c | echA10 | 4e-29 | 32.27% (251) | enoyl-CoA hydratase |
| M. gilvum PYR-GCK | Mflv_4359 | - | 1e-35 | 35.06% (251) | enoyl-CoA hydratase/isomerase |
| M. tuberculosis H37Rv | Rv1142c | echA10 | 4e-29 | 32.27% (251) | enoyl-CoA hydratase |
| M. leprae Br4923 | MLBr_01241 | - | 2e-24 | 37.93% (203) | enoyl-CoA hydratase |
| M. marinum M | MMAR_4022 | echA10_1 | 2e-33 | 34.27% (248) | enoyl-CoA hydratase EchA10_1 |
| M. avium 104 | MAV_5085 | - | 2e-38 | 38.58% (254) | enoyl-CoA hydratase |
| M. smegmatis MC2 155 | MSMEG_2220 | - | 4e-35 | 35.46% (251) | enoyl-CoA hydratase/isomerase |
| M. thermoresistible (build 8) | TH_4335 | - | 3e-39 | 36.25% (251) | PUTATIVE putative Enoyl-CoA hydratase |
| M. ulcerans Agy99 | MUL_3887 | echA10_1 | 1e-32 | 34.27% (248) | enoyl-CoA hydratase EchA10_1 |
| M. vanbaalenii PYR-1 | Mvan_4207 | - | 4e-34 | 36.82% (258) | enoyl-CoA hydratase/isomerase |
CLUSTAL 2.0.9 multiple sequence alignment
Mb1174c|M.bovis_AF2122/97 --------------------------------------------------
Rv1142c|M.tuberculosis_H37Rv --------------------------------------------------
Mflv_4359|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_2220|M.smegmatis_MC2_155 --------------------------------------------------
MMAR_4022|M.marinum_M --------------------------------------------------
MUL_3887|M.ulcerans_Agy99 --------------------------------------------------
MAB_0905|M.abscessus_ATCC_1997 --------------------------------------------------
TH_4335|M.thermoresistible__bu MSADTMSDTRVGTAQRLYEALARGDRDALDELLHPDFVGRAAEGLPLQMG
MAV_5085|M.avium_104 --------------------------------------------------
Mvan_4207|M.vanbaalenii_PYR-1 --------------------------------------------------
MLBr_01241|M.leprae_Br4923 --------------------------------------------------
Mb1174c|M.bovis_AF2122/97 --------------------------------------------------
Rv1142c|M.tuberculosis_H37Rv --------------------------------------------------
Mflv_4359|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_2220|M.smegmatis_MC2_155 --------------------------------------------------
MMAR_4022|M.marinum_M --------------------------------------------------
MUL_3887|M.ulcerans_Agy99 --------------------------------------------------
MAB_0905|M.abscessus_ATCC_1997 --------------------------------------------------
TH_4335|M.thermoresistible__bu GEHVGAEAMRTNLWWRIGEHFKVRALAEDFQILPDGRLMVGGRYRGSARR
MAV_5085|M.avium_104 --------------------------------------------------
Mvan_4207|M.vanbaalenii_PYR-1 --------------------------------------------------
MLBr_01241|M.leprae_Br4923 --------------------------------------------------
Mb1174c|M.bovis_AF2122/97 -------------------------------MSNYRIDTRTIVPGLAVTL
Rv1142c|M.tuberculosis_H37Rv -------------------------------MSNYRIDTRTIVPGLAVTL
Mflv_4359|M.gilvum_PYR-GCK -------------------------------MRDD-----ADAGAVRLTR
MSMEG_2220|M.smegmatis_MC2_155 -------------------------------MALERPGLLVSDGSVTVTR
MMAR_4022|M.marinum_M -------------------------------MSLEADS-AGPEGSVTSRR
MUL_3887|M.ulcerans_Agy99 -------------------------------MSLEADS-AGPEGSVTSRR
MAB_0905|M.abscessus_ATCC_1997 ------------------------------------MTQTAPAAVAYSVN
TH_4335|M.thermoresistible__bu SGKPLDAAFIHLIAFGDDGRVVALEQLTDTAAWHEALDAPAELETIDYRV
MAV_5085|M.avium_104 ---------------------------------------MTN--VLTSND
Mvan_4207|M.vanbaalenii_PYR-1 ---------------------------------------MVDDQVLLSTD
MLBr_01241|M.leprae_Br4923 -----------------------MSQTDASCTIAELPYRSVTDLVVLDFP
Mb1174c|M.bovis_AF2122/97 ADGVLSVTIDRPESLNSLTKPVLAGMADAIEGAATDPRVKVVRLGGAGRG
Rv1142c|M.tuberculosis_H37Rv ADGVLSVTIDRPESLNSLTKPVLAGMADAIEGAATDPRVKVVRLGGAGRG
Mflv_4359|M.gilvum_PYR-GCK DDAVLHITLDRPSRRNSLSRTMIGTLVDTLTEAASDDSLRAIHLTGVGKD
MSMEG_2220|M.smegmatis_MC2_155 DGAVLRIVLDRPSRRNSLDHTMVSELVTTLTAAASDDSLRAVSLSGAGEH
MMAR_4022|M.marinum_M DGTLLRITLDRPSRRNSLTQNMIEMLLDTLGGAATDDSLRAILIRGAGAD
MUL_3887|M.ulcerans_Agy99 DGTLLRITLDRPSRRNSLTRNMIEMLLDTLGGAATDDSLRAILIRGAAAD
MAB_0905|M.abscessus_ATCC_1997 HAGVAAIVLDRPEASNALDRTMKTELLQALLAAGGDPAVRAVVMSAAGKN
TH_4335|M.thermoresistible__bu VNGVATVCLNRPEMRNAIDMRMGRETLEVARRIEGDHTVRCVLICGNGPA
MAV_5085|M.avium_104 -GPVRIVTLNRPGVRNAIDIPLRIELAEVLEAADADESVRSIVLTGAGRV
Mvan_4207|M.vanbaalenii_PYR-1 RDGVRTLTLNRPERRNALDARLWVELADALRDLKRDHDVRALVLTGAGGA
MLBr_01241|M.leprae_Br4923 RPEVALITLNRPGRMNSMALDLMKSLKQVLKRITYDHSVRVVVLTGAGRG
: : ::** *:: : . * :: : : . .
Mb1174c|M.bovis_AF2122/97 FSSGGAISVDDVWASGPPTDTVA-------EANRTVRAIVALPQPVVAVV
Rv1142c|M.tuberculosis_H37Rv FSSGGAISVDDVWASGPPTDTVA-------EANRTVRAIVALPQPVVAVV
Mflv_4359|M.gilvum_PYR-GCK FCAGSDWVATNSGGGKPRPGNLLRRV--PHQANRVVELLATIQLPVVCTV
MSMEG_2220|M.smegmatis_MC2_155 FCTGSDWVATNSSGHRPRTGDLVRRV--PHAAHRIVELVATIQLPVVCTV
MMAR_4022|M.marinum_M FCAGADWVAASTGTQRPRTGDLLRRI--PHAAHRVIELLHTIHLPVVCGV
MUL_3887|M.ulcerans_Agy99 FCAGADWVAASTGTQRHRTGDLLRRI--PHAAHRVIELLHTIHLPVVCGV
MAB_0905|M.abscessus_ATCC_1997 FCVGQDLAEHVE-ALRDDPAHAMDTV--REHYNPVLEALDAIKVPVVVAI
TH_4335|M.thermoresistible__bu LTVGGDISYFLD-GRSERFGDLFAEM--TTPFHQAFDILSRVPVPIVTAA
MAV_5085|M.avium_104 FCSGGDISTMQR-MESEDAKHRADLA--QR----VIRAIWNTAKPVVAAV
Mvan_4207|M.vanbaalenii_PYR-1 FCSGADIGTGEQ-IHP---RYKLDRL--TD----VALALHELAVPTIAKV
MLBr_01241|M.leprae_Br4923 FCSGADQKFTAPVPQVEGLTQPVRALRAMELLEEVILALRRLHQPVIAAI
: * : * :
Mb1174c|M.bovis_AF2122/97 QGPTVGCGVSLALACDLVLASDNAFFMLAHTNVGLMP-DGGASALVQAAI
Rv1142c|M.tuberculosis_H37Rv QGPTVGCGVSLALACDLVLASDNAFFMLAHTNVGLMP-DGGASALVQAAI
Mflv_4359|M.gilvum_PYR-GCK RGWAVGLGCNLALAADFTVATPEANLWEPFIDRGFSP-DSGATWLLPRLA
MSMEG_2220|M.smegmatis_MC2_155 RGWAVGLGCNLALAADFTVADADATFWEPFLSRGFSP-DSGATWLLPRLA
MMAR_4022|M.marinum_M QGWAAGLGANLALAADFTVASSDATFWEPFVVRGFSP-DSGSTWLLPRLV
MUL_3887|M.ulcerans_Agy99 QGWAAGLGANLALAADFTVATSDATFWEPFVVRGFSP-DSGSTWLLPRLV
MAB_0905|M.abscessus_ATCC_1997 NGACVGAGLGLALGADIRIAGQRAKFGTAFTGIGLAA-DSALSASLPRLI
TH_4335|M.thermoresistible__bu HGAVAGGGLGYVYAADIVVAAEGTRFVTAFAGIGLSG-DGGGTWHLPRLI
MAV_5085|M.avium_104 EGAAFGAGAALALACDRVVAARDARFATTFTNVGLAG-DMGTFVSLPRRV
Mvan_4207|M.vanbaalenii_PYR-1 TGIAVGAGWNLALGCDLVVATPESRFCQIFSKRGLSV-DLGGSWLLPRIV
MLBr_01241|M.leprae_Br4923 NGPAIGGGLCLALAADVRVASTRAYFRAAGINNGLSASELGLSYLLPRAV
* * * . ..* :* : : *: : . :
Mb1174c|M.bovis_AF2122/97 GRIRAMHMALLPDRVPAAEALSWGLVSAVYPAADFDAEVDKLISRLLAGP
Rv1142c|M.tuberculosis_H37Rv GRIRAMHMALLPDRVPAAEALSWGLVSAVYPAADFDAEVDKLISRLLAGP
Mflv_4359|M.gilvum_PYR-GCK GVARAKRMLLLGEKVTGADAADWGLIHQAVPQDEIAGVAEDLMHRLAAGP
MSMEG_2220|M.smegmatis_MC2_155 GLTRAKQMLLLGEKVSGTEAADWGLIHGAVPAAELETAAEDLIDRLASGP
MMAR_4022|M.marinum_M GLARARRMLLLGEQVTAPEAADWGLIHQVVDATALDSAVDELLTRLARGP
MUL_3887|M.ulcerans_Agy99 GLARARRMLLLGEQVTAPEAADWGLIHQVVDATDLDSAVDELLTRLARGP
MAB_0905|M.abscessus_ATCC_1997 GASRATAMFLLGDTIDAPTAHTWGLVHEVVDEGSPADVANSVAGRLAGGP
TH_4335|M.thermoresistible__bu GPRRAAEAYLRNQPIEAEQALEWGLINEIVPPDRLREHAEQLAAELAAGP
MAV_5085|M.avium_104 GIARARQMLLLPQPIGAEEAAALGMVDALTDPGHTLEAATRDAQNLAAGP
Mvan_4207|M.vanbaalenii_PYR-1 GLQQAKRLVLLAEMIGADEARDLGLVTWVKPSGEIDAFVDDLADRLAGGP
MLBr_01241|M.leprae_Br4923 GSSRAFEIMLSGRDVGAEEAEQIGLVSYRVSDDRLLDTCYSIAARMATFS
* :* * : . * *:: .: .
Mb1174c|M.bovis_AF2122/97 ALAIAKTKNAINAATLTELAPTLLR--ELDGQALLLRTDDFAEGATAFQQ
Rv1142c|M.tuberculosis_H37Rv ALAIAKTKNAINAATLTELAPTLLR--ELDGQALLLRTDDFAEGATAFQQ
Mflv_4359|M.gilvum_PYR-GCK TVAIGLAKRSIHYGMHATLPQSMDH--ELSDLELACRTSDFKEGLAAFRD
MSMEG_2220|M.smegmatis_MC2_155 TVAIGLAKQAIAFGQHATLIQSMNQ--ELSNLELSCRTHDFKEGLAAFRE
MMAR_4022|M.marinum_M TVAIGLAKQALNHGQHATLTESMTH--ELFSLELTCRTSDFKEGLTAFRQ
MUL_3887|M.ulcerans_Agy99 TVAIGLAKQALNHGQHATLTESMTH--ELFNLELTCRTSDFKEGLTAFRQ
MAB_0905|M.abscessus_ATCC_1997 TAAFSEVKELLRRNAVAPLGDVLER--EASAQQRLGASRDHSAAVEAFLA
TH_4335|M.thermoresistible__bu TLAFGTMRVLLRDSWRNDLSAQLAA--ETRGIKLTGDSEDAAAAINAFAA
MAV_5085|M.avium_104 AEAFGVIKALLAIAPTLHPLDALEE--EASYQARLFGTDDFVEGVAAFRD
Mvan_4207|M.vanbaalenii_PYR-1 PFALAQSKALLNDGANATLREALAN--EARAQPGNFATADSVEAYAAFAA
MLBr_01241|M.leprae_Br4923 RSGTELTKRALWGGLDAASLDKHMQSESLAQLFIALHTSNFEEAAAPCTE
. : : . : : . .
Mb1174c|M.bovis_AF2122/97 RRTPMFTGR-------------
Rv1142c|M.tuberculosis_H37Rv RRTPMFTGR-------------
Mflv_4359|M.gilvum_PYR-GCK RRAPGFTGR-------------
MSMEG_2220|M.smegmatis_MC2_155 RRDPDFQGR-------------
MMAR_4022|M.marinum_M HRTPKFEGR-------------
MUL_3887|M.ulcerans_Agy99 HRTPKFEGR-------------
MAB_0905|M.abscessus_ATCC_1997 KDKPVFVGR-------------
TH_4335|M.thermoresistible__bu KRTPMFIGR-------------
MAV_5085|M.avium_104 KRRPSFG--QRQGVRP------
Mvan_4207|M.vanbaalenii_PYR-1 KREPEFTGAWVQYEKPTQKDEE
MLBr_01241|M.leprae_Br4923 KRPTVLVDARGCATSPG-----
: . :