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M. thermoresistible (build 8) TH_4335 (-)

annotation: putative Enoyl-CoA hydratase
coordinates: 36855 - 38066
length: 404

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_4335--100% (404)putative Enoyl-CoA hydratase
M. thermoresistible (build 8)TH_3232-3e-3834.10% (261) PUTATIVE Enoyl-CoA hydratase
M. thermoresistible (build 8)TH_3726-3e-3433.46% (269) PUTATIVE probable enoyl-CoA hydratase

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb1174cechA102e-2328.35% (254) enoyl-CoA hydratase
M. gilvum PYR-GCKMflv_2902-4e-3733.20% (259) enoyl-CoA hydratase/isomerase
M. tuberculosis H37RvRv1142cechA102e-2328.35% (254) enoyl-CoA hydratase
M. leprae Br4923MLBr_02402-1e-2128.00% (250) enoyl-CoA hydratase
M. abscessus ATCC 19977MAB_0905-7e-3936.25% (251) putative enoyl-CoA hydratase/isomerase
M. marinum MMMAR_4022echA10_13e-3131.45% (248) enoyl-CoA hydratase EchA10_1
M. avium 104MAV_5086-2e-3233.21% (268) enoyl-CoA hydratase
M. smegmatis MC2 155MSMEG_4299-7e-4135.02% (257) enoyl-CoA hydratase/isomerase
M. ulcerans Agy99MUL_3887echA10_12e-3031.05% (248) enoyl-CoA hydratase EchA10_1
M. vanbaalenii PYR-1Mvan_3603-1e-4034.75% (259) enoyl-CoA hydratase/isomerase

CLUSTAL 2.0.9 multiple sequence alignment


TH_4335|M.thermoresistible__bu      MSADTMSDTRVGTAQRLYEALARGDRDALDELLHPDFVGRAAEGLPLQMG
MAB_0905|M.abscessus_ATCC_1997      --------------------------------------------------
Mflv_2902|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_3603|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_4299|M.smegmatis_MC2_155      --------------------------------------------------
MLBr_02402|M.leprae_Br4923          --------------------------------------------------
MAV_5086|M.avium_104                --------------------------------------------------
Mb1174c|M.bovis_AF2122/97           --------------------------------------------------
Rv1142c|M.tuberculosis_H37Rv        --------------------------------------------------
MMAR_4022|M.marinum_M               --------------------------------------------------
MUL_3887|M.ulcerans_Agy99           --------------------------------------------------
                                                                                      

TH_4335|M.thermoresistible__bu      GEHVGAEAMRTNLWWRIGEHFKVRALAEDFQILPDGRLMVGGRYRGSARR
MAB_0905|M.abscessus_ATCC_1997      --------------------------------------------------
Mflv_2902|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_3603|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_4299|M.smegmatis_MC2_155      --------------------------------------------------
MLBr_02402|M.leprae_Br4923          --------------------------------------------------
MAV_5086|M.avium_104                --------------------------------------------------
Mb1174c|M.bovis_AF2122/97           --------------------------------------------------
Rv1142c|M.tuberculosis_H37Rv        --------------------------------------------------
MMAR_4022|M.marinum_M               --------------------------------------------------
MUL_3887|M.ulcerans_Agy99           --------------------------------------------------
                                                                                      

TH_4335|M.thermoresistible__bu      SGKPLDAAFIHLIAFGDDGRVVALEQLTDTAAWHEALDAPAELETIDYRV
MAB_0905|M.abscessus_ATCC_1997      ------------------------------------MTQTAPAAVAYSVN
Mflv_2902|M.gilvum_PYR-GCK          -------------------------------------MTD--YQTITLEQ
Mvan_3603|M.vanbaalenii_PYR-1       -------------------------------------MTE--YQTITFEQ
MSMEG_4299|M.smegmatis_MC2_155      -------------------------------------MTEISYEAIAFEQ
MLBr_02402|M.leprae_Br4923          ----------------------------------------MKYDTILVDG
MAV_5086|M.avium_104                ------------------------------------MTTSLDAPVLREVD
Mb1174c|M.bovis_AF2122/97           -------------------------------MSNYRIDTRTIVPGLAVTL
Rv1142c|M.tuberculosis_H37Rv        -------------------------------MSNYRIDTRTIVPGLAVTL
MMAR_4022|M.marinum_M               --------------------------------MSLEADSAGPEGSVTSRR
MUL_3887|M.ulcerans_Agy99           --------------------------------MSLEADSAGPEGSVTSRR
                                                                                      

TH_4335|M.thermoresistible__bu      VNGVATVCLNRPEMRNAIDMRMGRETLEVARRIEGDHTVRCVLICGNGPA
MAB_0905|M.abscessus_ATCC_1997      HAGVAAIVLDRPEASNALDRTMKTELLQALLAAGGDPAVRAVVMSAAGKN
Mflv_2902|M.gilvum_PYR-GCK          SGPVARITLNRPEAANGMNGTMTRELADAAARCDTP-ATKVVVLTGAGRF
Mvan_3603|M.vanbaalenii_PYR-1       AGVVARITLNRPDAANGMNGTMTRELADAAARCDTA-ATKVVVITGAGRF
MSMEG_4299|M.smegmatis_MC2_155      SGPITRITLNRPDAANGMNDTMTRELADAARRADTS-GAKVVVLTGSGRF
MLBr_02402|M.leprae_Br4923          YQRVGIITLNRPQALNALNSQMMNEITNAAKELDIDPDVGAILITGSPKV
MAV_5086|M.avium_104                ADGVARVRLNRPQTSNGLNVETLKALHDAVLTCHADPTVKVVLLSGAGRN
Mb1174c|M.bovis_AF2122/97           ADGVLSVTIDRPESLNSLTKPVLAGMADAIEGAATDPRVKVVRLGGAGRG
Rv1142c|M.tuberculosis_H37Rv        ADGVLSVTIDRPESLNSLTKPVLAGMADAIEGAATDPRVKVVRLGGAGRG
MMAR_4022|M.marinum_M               DGTLLRITLDRPSRRNSLTQNMIEMLLDTLGGAATDDSLRAILIRGAGAD
MUL_3887|M.ulcerans_Agy99           DGTLLRITLDRPSRRNSLTRNMIEMLLDTLGGAATDDSLRAILIRGAAAD
                                       :  : ::**.  *.:         :.            : : .    

TH_4335|M.thermoresistible__bu      LTVGGDISYFLDGRSERFG-DLFAEMTTPFHQAFDILSRVPVPIVTAAHG
MAB_0905|M.abscessus_ATCC_1997      FCVGQDLAEHVEALRDDPA-HAMDTVREHYNPVLEALDAIKVPVVVAING
Mflv_2902|M.gilvum_PYR-GCK          FCAGGDLKDFASAPSRG---QHVKGVADDLHRAISSFARMDAVVITVVNG
Mvan_3603|M.vanbaalenii_PYR-1       FCAGGDLKDFASAPSRG---RHVKGVADDLHRAISTFARMDAVVITAVNG
MSMEG_4299|M.smegmatis_MC2_155      FSAGGDLKAFSTAPSRG---AFIKGVADDLHRAISSFARMDAVLITAVNG
MLBr_02402|M.leprae_Br4923          FAAGADIKEMASLT-------FTDAFDADFFSAWGKLAAVRTPMIAAVAG
MAV_5086|M.avium_104                FCAGGDVHTFESKGADLP--DYLREATAWLQLATAALIQLRAPVVTAVQG
Mb1174c|M.bovis_AF2122/97           FSSGGAISVDDVWASGPPT-----DTVAEANRTVRAIVALPQPVVAVVQG
Rv1142c|M.tuberculosis_H37Rv        FSSGGAISVDDVWASGPPT-----DTVAEANRTVRAIVALPQPVVAVVQG
MMAR_4022|M.marinum_M               FCAGADWVAASTGTQRPRTGDLLRRIPHAAHRVIELLHTIHLPVVCGVQG
MUL_3887|M.ulcerans_Agy99           FCAGADWVAASTGTQRHRTGDLLRRIPHAAHRVIELLHTIHLPVVCGVQG
                                    :  *                            .   :  :   ::    *

TH_4335|M.thermoresistible__bu      AVAGGG-LGYVYAADIVVAAEGTRFVTAFAGIGLSGDGGGTWHLPRLIGP
MAB_0905|M.abscessus_ATCC_1997      ACVGAG-LGLALGADIRIAGQRAKFGTAFTGIGLAADSALSASLPRLIGA
Mflv_2902|M.gilvum_PYR-GCK          TAAGAG-FSLAVSGDLVLAAESASFTMAYTKVGLSPDGSASYYLPRLIGI
Mvan_3603|M.vanbaalenii_PYR-1       TAAGAG-FSLAVSGDLVLAAESASFTMAYTRVGLSPDGSASYHLPRLIGI
MSMEG_4299|M.smegmatis_MC2_155      TAAGAG-FSIAVTGDLVLAAESASFTMAYTKVGLSPDGSASYYLPRLVGM
MLBr_02402|M.leprae_Br4923          YALGGG-CELAMMCDLLIAADTAKFGQPEIKLGVLPGMGGSQRLTRAIGK
MAV_5086|M.avium_104                FAAGGGGLGLVCASDVVLAGRSAKFFSGAVRVGMAPDGGSSVTLTQLVGL
Mb1174c|M.bovis_AF2122/97           PTVGCG-VSLALACDLVLASDNAFFMLAHTNVGLMPDGGASALVQAAIGR
Rv1142c|M.tuberculosis_H37Rv        PTVGCG-VSLALACDLVLASDNAFFMLAHTNVGLMPDGGASALVQAAIGR
MMAR_4022|M.marinum_M               WAAGLG-ANLALAADFTVASSDATFWEPFVVRGFSPDSGSTWLLPRLVGL
MUL_3887|M.ulcerans_Agy99           WAAGLG-ANLALAADFTVATSDATFWEPFVVRGFSPDSGSTWLLPRLVGL
                                       * *    .   *. :*   : *       *.  . . :  :   :* 

TH_4335|M.thermoresistible__bu      RRAAEAYLRNQPIEAEQALEWGLINEIVPPDRLREHAEQLAAELAAGPTL
MAB_0905|M.abscessus_ATCC_1997      SRATAMFLLGDTIDAPTAHTWGLVHEVVDEGSPADVANSVAGRLAGGPTA
Mflv_2902|M.gilvum_PYR-GCK          AKTKQLMLTNRVLSADEASRWGLVTEVVADDELAARADALAGQMAATAAG
Mvan_3603|M.vanbaalenii_PYR-1       AKTKQLMLTNRTLSAQEALQWGLVGEVVADDRLQARADELAEQMAETSAG
MSMEG_4299|M.smegmatis_MC2_155      RRAQELMLTNRTLSATEAYEWGLVTEVVPDADLADRATKLAEQVAAGSAG
MLBr_02402|M.leprae_Br4923          AKAMDLILTGRTIDAAEAERSGLVSRVVLADDLLPEAKAVATTISQMSRS
MAV_5086|M.avium_104                RQALRILLTNPTLGAEEAAAIGLITDVVDDDALTEEAERIAKTLAAMPPK
Mb1174c|M.bovis_AF2122/97           IRAMHMALLPDRVPAAEALSWGLVSAVYPAADFDAEVDKLISRLLAGPAL
Rv1142c|M.tuberculosis_H37Rv        IRAMHMALLPDRVPAAEALSWGLVSAVYPAADFDAEVDKLISRLLAGPAL
MMAR_4022|M.marinum_M               ARARRMLLLGEQVTAPEAADWGLIHQVVDATALDSAVDELLTRLARGPTV
MUL_3887|M.ulcerans_Agy99           ARARRMLLLGEQVTAPEAADWGLIHQVVDATDLDSAVDELLTRLARGPTV
                                     ::    *    : *  *   **:  :         .  :   :   .  

TH_4335|M.thermoresistible__bu      AFGTMRVLLRDSWRNDLSAQLAAETRGIKLTGDSEDAAAAINAFAAKRTP
MAB_0905|M.abscessus_ATCC_1997      AFSEVKELLRRNAVAPLGDVLEREASAQQRLGASRDHSAAVEAFLAKDKP
Mflv_2902|M.gilvum_PYR-GCK          SNGGVKALLLDTFSNGLEQQMELEGRLIAQRAESADGREGVDAFLAKRKP
Mvan_3603|M.vanbaalenii_PYR-1       SNGGVKALLSDTFANGLEQQMELEGRLIAARAESADGREGVDAFLAKRRP
MSMEG_4299|M.smegmatis_MC2_155      SNGAVKSLLLSSLKNSLEEQMEAEGRFIAARADSADGREGVDAFLGKRRP
MLBr_02402|M.leprae_Br4923          ATRMAKEAVNRSFESTLAEGLLHERRLFHSTFVTDDQSEGMAAFIEKRAP
MAV_5086|M.avium_104                ALSATKRLVWSGVGVPVESRLAEEARIVSELSGTADALEGLRAVIERRPP
Mb1174c|M.bovis_AF2122/97           AIAKTKNAINAATLTELAPTLLRELDGQALLLRTDDFAEGATAFQQRRTP
Rv1142c|M.tuberculosis_H37Rv        AIAKTKNAINAATLTELAPTLLRELDGQALLLRTDDFAEGATAFQQRRTP
MMAR_4022|M.marinum_M               AIGLAKQALNHGQHATLTESMTHELFSLELTCRTSDFKEGLTAFRQHRTP
MUL_3887|M.ulcerans_Agy99           AIGLAKQALNHGQHATLTESMTHELFNLELTCRTSDFKEGLTAFRQHRTP
                                    :    :  :       :   :  *         : *   .  *.  :  *

TH_4335|M.thermoresistible__bu      MFIGR---
MAB_0905|M.abscessus_ATCC_1997      VFVGR---
Mflv_2902|M.gilvum_PYR-GCK          EFSPGG--
Mvan_3603|M.vanbaalenii_PYR-1       KFGAQSAG
MSMEG_4299|M.smegmatis_MC2_155      EFA-----
MLBr_02402|M.leprae_Br4923          QFTHR---
MAV_5086|M.avium_104                RFTGA---
Mb1174c|M.bovis_AF2122/97           MFTGR---
Rv1142c|M.tuberculosis_H37Rv        MFTGR---
MMAR_4022|M.marinum_M               KFEGR---
MUL_3887|M.ulcerans_Agy99           KFEGR---
                                     *