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VSLEADSAGPEGSVTSRRDGTLLRITLDRPSRRNSLTRNMIEMLLDTLGGAATDDSLRAILIRGAAADFC AGADWVAASTGTQRHRTGDLLRRIPHAAHRVIELLHTIHLPVVCGVQGWAAGLGANLALAADFTVATSDA TFWEPFVVRGFSPDSGSTWLLPRLVGLARARRMLLLGEQVTAPEAADWGLIHQVVDATDLDSAVDELLTR LARGPTVAIGLAKQALNHGQHATLTESMTHELFNLELTCRTSDFKEGLTAFRQHRTPKFEGR
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. ulcerans Agy99 | MUL_3887 | echA10_1 | - | 100% (272) | enoyl-CoA hydratase EchA10_1 |
| M. ulcerans Agy99 | MUL_0985 | echA10 | 3e-37 | 34.47% (264) | enoyl-CoA hydratase |
| M. ulcerans Agy99 | MUL_2758 | echA8_5 | 7e-25 | 30.43% (230) | enoyl-CoA hydratase, EchA8_5 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1174c | echA10 | 7e-40 | 36.40% (261) | enoyl-CoA hydratase |
| M. gilvum PYR-GCK | Mflv_4359 | - | 6e-98 | 65.90% (261) | enoyl-CoA hydratase/isomerase |
| M. tuberculosis H37Rv | Rv1142c | echA10 | 7e-40 | 36.40% (261) | enoyl-CoA hydratase |
| M. leprae Br4923 | MLBr_02402 | - | 1e-25 | 31.60% (250) | enoyl-CoA hydratase |
| M. abscessus ATCC 19977 | MAB_0905 | - | 1e-32 | 34.27% (248) | putative enoyl-CoA hydratase/isomerase |
| M. marinum M | MMAR_4022 | echA10_1 | 1e-151 | 97.79% (272) | enoyl-CoA hydratase EchA10_1 |
| M. avium 104 | MAV_1583 | - | 1e-101 | 70.38% (260) | enoyl-CoA hydratase/isomerase family protein |
| M. smegmatis MC2 155 | MSMEG_2220 | - | 1e-102 | 67.18% (262) | enoyl-CoA hydratase/isomerase |
| M. thermoresistible (build 8) | TH_2905 | - | 1e-100 | 66.15% (260) | PUTATIVE enoyl-CoA hydratase/isomerase |
| M. vanbaalenii PYR-1 | Mvan_1985 | - | 1e-101 | 67.43% (261) | enoyl-CoA hydratase/isomerase |
CLUSTAL 2.0.9 multiple sequence alignment
Mb1174c|M.bovis_AF2122/97 MSNYRIDTRTIVPGLAVTLADGVLSVTIDRPESLNSLTKPVLAGMADAIE
Rv1142c|M.tuberculosis_H37Rv MSNYRIDTRTIVPGLAVTLADGVLSVTIDRPESLNSLTKPVLAGMADAIE
MUL_3887|M.ulcerans_Agy99 -MSLEADSAGPEGSVTSRRDGTLLRITLDRPSRRNSLTRNMIEMLLDTLG
MMAR_4022|M.marinum_M -MSLEADSAGPEGSVTSRRDGTLLRITLDRPSRRNSLTQNMIEMLLDTLG
MAV_1583|M.avium_104 --------------MAVHRQGAVLRLTLDRPSRRNALTQLMIATLVDALT
Mflv_4359|M.gilvum_PYR-GCK MRDD-----ADAGAVRLTRDDAVLHITLDRPSRRNSLSRTMIGTLVDTLT
Mvan_1985|M.vanbaalenii_PYR-1 MRD-------DAGAVRVVRDDAVLRITLDRPTRRNSLSHAMIDDLVGTLT
MSMEG_2220|M.smegmatis_MC2_155 MALERPGLLVSDGSVTVTRDGAVLRIVLDRPSRRNSLDHTMVSELVTTLT
TH_2905|M.thermoresistible__bu --------------VTVRRDGTVVRLTLDRPDRRNSLSPTMVDTLIRTLT
MAB_0905|M.abscessus_ATCC_1997 -----MTQTAPAAVAYSVNHAGVAAIVLDRPEASNALDRTMKTELLQALL
MLBr_02402|M.leprae_Br4923 ---------MKYDTILVDGYQRVGIITLNRPQALNALNSQMMNEITNAAK
: :.::** *:* : : :
Mb1174c|M.bovis_AF2122/97 GAATDPRVKVVRLGGAGRGFSSGGAISVDDVWASGPPTD------TVAEA
Rv1142c|M.tuberculosis_H37Rv GAATDPRVKVVRLGGAGRGFSSGGAISVDDVWASGPPTD------TVAEA
MUL_3887|M.ulcerans_Agy99 GAATDDSLRAILIRGAAADFCAGADWVAAS-TGTQRHRTGDLLRRIPHAA
MMAR_4022|M.marinum_M GAATDDSLRAILIRGAGADFCAGADWVAAS-TGTQRPRTGDLLRRIPHAA
MAV_1583|M.avium_104 AAASDDSLRVVHIVGAGDDFCAGADWVAVNDPGGPRPRAGDLVRRIPHAA
Mflv_4359|M.gilvum_PYR-GCK EAASDDSLRAIHLTGVGKDFCAGSDWVATNSGGG-KPRPGNLLRRVPHQA
Mvan_1985|M.vanbaalenii_PYR-1 SAASDDSVRAIHLTGAGDDFCSGADWVTTNSSDR-KPRPGNLVRRIPHAA
MSMEG_2220|M.smegmatis_MC2_155 AAASDDSLRAVSLSGAGEHFCTGSDWVATNSSGH-RPRTGDLVRRVPHAA
TH_2905|M.thermoresistible__bu SAATDDGLRAVLIEGAGDTFCSGSDWVATNESGSDRPRTGHLLRRLPHTG
MAB_0905|M.abscessus_ATCC_1997 AAGGDPAVRAVVMSAAGKNFCVGQDLAEHVEALRDDPAH--AMDTVREHY
MLBr_02402|M.leprae_Br4923 ELDIDPDVGAILITGSPKVFAAGADIKEMASLTFTDAFD--------ADF
* : .: : . *. *
Mb1174c|M.bovis_AF2122/97 NRTVRAIVALPQPVVAVVQGPTVGCGVSLALACDLVLASDNAFFMLAHTN
Rv1142c|M.tuberculosis_H37Rv NRTVRAIVALPQPVVAVVQGPTVGCGVSLALACDLVLASDNAFFMLAHTN
MUL_3887|M.ulcerans_Agy99 HRVIELLHTIHLPVVCGVQGWAAGLGANLALAADFTVATSDATFWEPFVV
MMAR_4022|M.marinum_M HRVIELLHTIHLPVVCGVQGWAAGLGANLALAADFTVASSDATFWEPFVV
MAV_1583|M.avium_104 HRVIELVAGIQLPVVCSVRGWAVGFGCNLALAADFTVAAADAVFWEPFVE
Mflv_4359|M.gilvum_PYR-GCK NRVVELLATIQLPVVCTVRGWAVGLGCNLALAADFTVATPEANLWEPFID
Mvan_1985|M.vanbaalenii_PYR-1 NRVVELVATIQLPVVCTVRGWAVGLGANLALAADFTLATPEANLWEPFID
MSMEG_2220|M.smegmatis_MC2_155 HRIVELVATIQLPVVCTVRGWAVGLGCNLALAADFTVADADATFWEPFLS
TH_2905|M.thermoresistible__bu HRVIELVNTIHLPVVCAVRGWAVGLGCNLALAADFTVVADDAVLWEPFID
MAB_0905|M.abscessus_ATCC_1997 NPVLEALDAIKVPVVVAINGACVGAGLGLALGADIRIAGQRAKFGTAFTG
MLBr_02402|M.leprae_Br4923 FSAWGKLAAVRTPMIAAVAGYALGGGCELAMMCDLLIAADTAKFGQPEIK
: : *:: : * * * **: .*: :. * : .
Mb1174c|M.bovis_AF2122/97 VGLMPDGGASALVQAAIGRIRAMHMALLPDRVPAAEALSWGLVSAVYPAA
Rv1142c|M.tuberculosis_H37Rv VGLMPDGGASALVQAAIGRIRAMHMALLPDRVPAAEALSWGLVSAVYPAA
MUL_3887|M.ulcerans_Agy99 RGFSPDSGSTWLLPRLVGLARARRMLLLGEQVTAPEAADWGLIHQVVDAT
MMAR_4022|M.marinum_M RGFSPDSGSTWLLPRLVGLARARRMLLLGEQVTAPEAADWGLIHQVVDAT
MAV_1583|M.avium_104 RGFSPDSGSTWLLARLVGLARARRMLLLGEKVGGRDAADWGLIHRAVGGA
Mflv_4359|M.gilvum_PYR-GCK RGFSPDSGATWLLPRLAGVARAKRMLLLGEKVTGADAADWGLIHQAVPQD
Mvan_1985|M.vanbaalenii_PYR-1 RGFSPDSGSTWLLPRLAGVTRAKRMLLLGEKVTGADAADWGLIHQAVPAD
MSMEG_2220|M.smegmatis_MC2_155 RGFSPDSGATWLLPRLAGLTRAKQMLLLGEKVSGTEAADWGLIHGAVPAA
TH_2905|M.thermoresistible__bu RGFTPDSGSTWLLPRLVGLARAKRMLLLGEQISGADAVDWGLVHASVPAA
MAB_0905|M.abscessus_ATCC_1997 IGLAADSALSASLPRLIGASRATAMFLLGDTIDAPTAHTWGLVHEVVDEG
MLBr_02402|M.leprae_Br4923 LGVLPGMGGSQRLTRAIGKAKAMDLILTGRTIDAAEAERSGLVSRVVLAD
*. .. . : : * :* : * : . * **:
Mb1174c|M.bovis_AF2122/97 DFDAEVDKLISRLLAGPALAIAKTKNAINAATLTELAPTLLRELDGQALL
Rv1142c|M.tuberculosis_H37Rv DFDAEVDKLISRLLAGPALAIAKTKNAINAATLTELAPTLLRELDGQALL
MUL_3887|M.ulcerans_Agy99 DLDSAVDELLTRLARGPTVAIGLAKQALNHGQHATLTESMTHELFNLELT
MMAR_4022|M.marinum_M ALDSAVDELLTRLARGPTVAIGLAKQALNHGQHATLTESMTHELFSLELT
MAV_1583|M.avium_104 ELDDAAEELVGRLAAGPTAALGLAKQALSFGQHATLSQSLTQELFNLELS
Mflv_4359|M.gilvum_PYR-GCK EIAGVAEDLMHRLAAGPTVAIGLAKRSIHYGMHATLPQSMDHELSDLELA
Mvan_1985|M.vanbaalenii_PYR-1 EIDAAAEELVTRLASGPTVAIGLAKQAINYGMHATLPQSMAHELASLELA
MSMEG_2220|M.smegmatis_MC2_155 ELETAAEDLIDRLASGPTVAIGLAKQAIAFGQHATLIQSMNQELSNLELS
TH_2905|M.thermoresistible__bu DVDRTATDLAARLAGGPTVAIGLAKHALNFSQQATLPQAMDNELYNVELS
MAB_0905|M.abscessus_ATCC_1997 SPADVANSVAGRLAGGPTAAFSEVKELLRRNAVAPLGDVLEREASAQQRL
MLBr_02402|M.leprae_Br4923 DLLPEAKAVATTISQMSRSATRMAKEAVNRSFESTLAEGLLHERRLFHST
. : : . * .*. : : * : .*
Mb1174c|M.bovis_AF2122/97 LRTDDFAEGATAFQQRRTPMFTGR
Rv1142c|M.tuberculosis_H37Rv LRTDDFAEGATAFQQRRTPMFTGR
MUL_3887|M.ulcerans_Agy99 CRTSDFKEGLTAFRQHRTPKFEGR
MMAR_4022|M.marinum_M CRTSDFKEGLTAFRQHRTPKFEGR
MAV_1583|M.avium_104 CRTSDFKEGLEAFRQRRDPDFRGR
Mflv_4359|M.gilvum_PYR-GCK CRTSDFKEGLAAFRDRRAPGFTGR
Mvan_1985|M.vanbaalenii_PYR-1 CRTADFKEGLAAFRARRAPDFEGR
MSMEG_2220|M.smegmatis_MC2_155 CRTHDFKEGLAAFRERRDPDFQGR
TH_2905|M.thermoresistible__bu CRTADFKEGLAAFRDRRAPEFQGR
MAB_0905|M.abscessus_ATCC_1997 GASRDHSAAVEAFLAKDKPVFVGR
MLBr_02402|M.leprae_Br4923 FVTDDQSEGMAAFIEKRAPQFTHR
: * . ** : * * *