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ALERPGLLVSDGSVTVTRDGAVLRIVLDRPSRRNSLDHTMVSELVTTLTAAASDDSLRAVSLSGAGEHFC TGSDWVATNSSGHRPRTGDLVRRVPHAAHRIVELVATIQLPVVCTVRGWAVGLGCNLALAADFTVADADA TFWEPFLSRGFSPDSGATWLLPRLAGLTRAKQMLLLGEKVSGTEAADWGLIHGAVPAAELETAAEDLIDR LASGPTVAIGLAKQAIAFGQHATLIQSMNQELSNLELSCRTHDFKEGLAAFRERRDPDFQGR*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_2220 | - | - | 100% (273) | enoyl-CoA hydratase/isomerase |
| M. smegmatis MC2 155 | MSMEG_5185 | - | 6e-36 | 35.63% (261) | enoyl-CoA hydratase |
| M. smegmatis MC2 155 | MSMEG_4299 | - | 5e-32 | 29.89% (261) | enoyl-CoA hydratase/isomerase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1174c | echA10 | 2e-37 | 35.14% (259) | enoyl-CoA hydratase |
| M. gilvum PYR-GCK | Mflv_4359 | - | 1e-110 | 73.95% (261) | enoyl-CoA hydratase/isomerase |
| M. tuberculosis H37Rv | Rv1142c | echA10 | 2e-37 | 35.14% (259) | enoyl-CoA hydratase |
| M. leprae Br4923 | MLBr_01241 | - | 8e-23 | 31.89% (254) | enoyl-CoA hydratase |
| M. abscessus ATCC 19977 | MAB_0905 | - | 3e-35 | 35.46% (251) | putative enoyl-CoA hydratase/isomerase |
| M. marinum M | MMAR_4022 | echA10_1 | 1e-103 | 67.56% (262) | enoyl-CoA hydratase EchA10_1 |
| M. avium 104 | MAV_1583 | - | 1e-110 | 73.85% (260) | enoyl-CoA hydratase/isomerase family protein |
| M. thermoresistible (build 8) | TH_2905 | - | 1e-105 | 70.00% (260) | PUTATIVE enoyl-CoA hydratase/isomerase |
| M. ulcerans Agy99 | MUL_3887 | echA10_1 | 1e-102 | 67.18% (262) | enoyl-CoA hydratase EchA10_1 |
| M. vanbaalenii PYR-1 | Mvan_1985 | - | 1e-113 | 74.71% (261) | enoyl-CoA hydratase/isomerase |
CLUSTAL 2.0.9 multiple sequence alignment
Mb1174c|M.bovis_AF2122/97 --------MSNYRIDTRTIVPGLAVTLADGVLSVTIDRPESLNSLTKPVL
Rv1142c|M.tuberculosis_H37Rv --------MSNYRIDTRTIVPGLAVTLADGVLSVTIDRPESLNSLTKPVL
Mflv_4359|M.gilvum_PYR-GCK --------MRDD-----ADAGAVRLTRDDAVLHITLDRPSRRNSLSRTMI
Mvan_1985|M.vanbaalenii_PYR-1 --------MRD-------DAGAVRVVRDDAVLRITLDRPTRRNSLSHAMI
MSMEG_2220|M.smegmatis_MC2_155 --------MALERPGLLVSDGSVTVTRDGAVLRIVLDRPSRRNSLDHTMV
TH_2905|M.thermoresistible__bu ----------------------VTVRRDGTVVRLTLDRPDRRNSLSPTMV
MMAR_4022|M.marinum_M ---------MSLEADSAGPEGSVTSRRDGTLLRITLDRPSRRNSLTQNMI
MUL_3887|M.ulcerans_Agy99 ---------MSLEADSAGPEGSVTSRRDGTLLRITLDRPSRRNSLTRNMI
MAV_1583|M.avium_104 ----------------------MAVHRQGAVLRLTLDRPSRRNALTQLMI
MAB_0905|M.abscessus_ATCC_1997 -------------MTQTAPAAVAYSVNHAGVAAIVLDRPEASNALDRTMK
MLBr_01241|M.leprae_Br4923 MSQTDASCTIAELPYRSVTDLVVLDFPRPEVALITLNRPGRMNSMALDLM
: :.::** *:: :
Mb1174c|M.bovis_AF2122/97 AGMADAIEGAATDPRVKVVRLGGAGRGFSSGGAISVDDVWASGPPTD---
Rv1142c|M.tuberculosis_H37Rv AGMADAIEGAATDPRVKVVRLGGAGRGFSSGGAISVDDVWASGPPTD---
Mflv_4359|M.gilvum_PYR-GCK GTLVDTLTEAASDDSLRAIHLTGVGKDFCAGSDWVATNSGGG-KPRPGNL
Mvan_1985|M.vanbaalenii_PYR-1 DDLVGTLTSAASDDSVRAIHLTGAGDDFCSGADWVTTNSSDR-KPRPGNL
MSMEG_2220|M.smegmatis_MC2_155 SELVTTLTAAASDDSLRAVSLSGAGEHFCTGSDWVATNSSGH-RPRTGDL
TH_2905|M.thermoresistible__bu DTLIRTLTSAATDDGLRAVLIEGAGDTFCSGSDWVATNESGSDRPRTGHL
MMAR_4022|M.marinum_M EMLLDTLGGAATDDSLRAILIRGAGADFCAGADWVAAS-TGTQRPRTGDL
MUL_3887|M.ulcerans_Agy99 EMLLDTLGGAATDDSLRAILIRGAAADFCAGADWVAAS-TGTQRHRTGDL
MAV_1583|M.avium_104 ATLVDALTAAASDDSLRVVHIVGAGDDFCAGADWVAVNDPGGPRPRAGDL
MAB_0905|M.abscessus_ATCC_1997 TELLQALLAAGGDPAVRAVVMSAAGKNFCVGQDLAEHVEALRDDPAH--A
MLBr_01241|M.leprae_Br4923 KSLKQVLKRITYDHSVRVVVLTGAGRGFCSGADQKFTAPVPQVEGLTQPV
: .: * ::.: : ... *. *
Mb1174c|M.bovis_AF2122/97 ----TVAEANRTVRAIVALPQPVVAVVQGPTVGCGVSLALACDLVLASDN
Rv1142c|M.tuberculosis_H37Rv ----TVAEANRTVRAIVALPQPVVAVVQGPTVGCGVSLALACDLVLASDN
Mflv_4359|M.gilvum_PYR-GCK -LRRVPHQANRVVELLATIQLPVVCTVRGWAVGLGCNLALAADFTVATPE
Mvan_1985|M.vanbaalenii_PYR-1 -VRRIPHAANRVVELVATIQLPVVCTVRGWAVGLGANLALAADFTLATPE
MSMEG_2220|M.smegmatis_MC2_155 -VRRVPHAAHRIVELVATIQLPVVCTVRGWAVGLGCNLALAADFTVADAD
TH_2905|M.thermoresistible__bu -LRRLPHTGHRVIELVNTIHLPVVCAVRGWAVGLGCNLALAADFTVVADD
MMAR_4022|M.marinum_M -LRRIPHAAHRVIELLHTIHLPVVCGVQGWAAGLGANLALAADFTVASSD
MUL_3887|M.ulcerans_Agy99 -LRRIPHAAHRVIELLHTIHLPVVCGVQGWAAGLGANLALAADFTVATSD
MAV_1583|M.avium_104 -VRRIPHAAHRVIELVAGIQLPVVCSVRGWAVGFGCNLALAADFTVAAAD
MAB_0905|M.abscessus_ATCC_1997 -MDTVREHYNPVLEALDAIKVPVVVAINGACVGAGLGLALGADIRIAGQR
MLBr_01241|M.leprae_Br4923 RALRAMELLEEVILALRRLHQPVIAAINGPAIGGGLCLALAADVRVASTR
. : : : **: :.* * * ***..*. :.
Mb1174c|M.bovis_AF2122/97 AFFMLAHTNVGLMP-DGGASALVQAAIGRIRAMHMALLPDRVPAAEALSW
Rv1142c|M.tuberculosis_H37Rv AFFMLAHTNVGLMP-DGGASALVQAAIGRIRAMHMALLPDRVPAAEALSW
Mflv_4359|M.gilvum_PYR-GCK ANLWEPFIDRGFSP-DSGATWLLPRLAGVARAKRMLLLGEKVTGADAADW
Mvan_1985|M.vanbaalenii_PYR-1 ANLWEPFIDRGFSP-DSGSTWLLPRLAGVTRAKRMLLLGEKVTGADAADW
MSMEG_2220|M.smegmatis_MC2_155 ATFWEPFLSRGFSP-DSGATWLLPRLAGLTRAKQMLLLGEKVSGTEAADW
TH_2905|M.thermoresistible__bu AVLWEPFIDRGFTP-DSGSTWLLPRLVGLARAKRMLLLGEQISGADAVDW
MMAR_4022|M.marinum_M ATFWEPFVVRGFSP-DSGSTWLLPRLVGLARARRMLLLGEQVTAPEAADW
MUL_3887|M.ulcerans_Agy99 ATFWEPFVVRGFSP-DSGSTWLLPRLVGLARARRMLLLGEQVTAPEAADW
MAV_1583|M.avium_104 AVFWEPFVERGFSP-DSGSTWLLARLVGLARARRMLLLGEKVGGRDAADW
MAB_0905|M.abscessus_ATCC_1997 AKFGTAFTGIGLAA-DSALSASLPRLIGASRATAMFLLGDTIDAPTAHTW
MLBr_01241|M.leprae_Br4923 AYFRAAGINNGLSASELGLSYLLPRAVGSSRAFEIMLSGRDVGAEEAEQI
* : . *: . : . : : * ** : * : . *
Mb1174c|M.bovis_AF2122/97 GLVSAVYPAADFDAEVDKLISRLLAGPALAIAKTKNAINAATLTELAPTL
Rv1142c|M.tuberculosis_H37Rv GLVSAVYPAADFDAEVDKLISRLLAGPALAIAKTKNAINAATLTELAPTL
Mflv_4359|M.gilvum_PYR-GCK GLIHQAVPQDEIAGVAEDLMHRLAAGPTVAIGLAKRSIHYGMHATLPQSM
Mvan_1985|M.vanbaalenii_PYR-1 GLIHQAVPADEIDAAAEELVTRLASGPTVAIGLAKQAINYGMHATLPQSM
MSMEG_2220|M.smegmatis_MC2_155 GLIHGAVPAAELETAAEDLIDRLASGPTVAIGLAKQAIAFGQHATLIQSM
TH_2905|M.thermoresistible__bu GLVHASVPAADVDRTATDLAARLAGGPTVAIGLAKHALNFSQQATLPQAM
MMAR_4022|M.marinum_M GLIHQVVDATALDSAVDELLTRLARGPTVAIGLAKQALNHGQHATLTESM
MUL_3887|M.ulcerans_Agy99 GLIHQVVDATDLDSAVDELLTRLARGPTVAIGLAKQALNHGQHATLTESM
MAV_1583|M.avium_104 GLIHRAVGGAELDDAAEELVGRLAAGPTAALGLAKQALSFGQHATLSQSL
MAB_0905|M.abscessus_ATCC_1997 GLVHEVVDEGSPADVANSVAGRLAGGPTAAFSEVKELLRRNAVAPLGDVL
MLBr_01241|M.leprae_Br4923 GLVSYRVSDDRLLDTCYSIAARMATFSRSGTELTKRALWGGLDAASLDKH
**: .: *: . . .*. : :
Mb1174c|M.bovis_AF2122/97 LR--ELDGQALLLRTDDFAEGATAFQQRRTPMFTGR--------
Rv1142c|M.tuberculosis_H37Rv LR--ELDGQALLLRTDDFAEGATAFQQRRTPMFTGR--------
Mflv_4359|M.gilvum_PYR-GCK DH--ELSDLELACRTSDFKEGLAAFRDRRAPGFTGR--------
Mvan_1985|M.vanbaalenii_PYR-1 AH--ELASLELACRTADFKEGLAAFRARRAPDFEGR--------
MSMEG_2220|M.smegmatis_MC2_155 NQ--ELSNLELSCRTHDFKEGLAAFRERRDPDFQGR--------
TH_2905|M.thermoresistible__bu DN--ELYNVELSCRTADFKEGLAAFRDRRAPEFQGR--------
MMAR_4022|M.marinum_M TH--ELFSLELTCRTSDFKEGLTAFRQHRTPKFEGR--------
MUL_3887|M.ulcerans_Agy99 TH--ELFNLELTCRTSDFKEGLTAFRQHRTPKFEGR--------
MAV_1583|M.avium_104 TQ--ELFNLELSCRTSDFKEGLEAFRQRRDPDFRGR--------
MAB_0905|M.abscessus_ATCC_1997 ER--EASAQQRLGASRDHSAAVEAFLAKDKPVFVGR--------
MLBr_01241|M.leprae_Br4923 MQSESLAQLFIALHTSNFEEAAAPCTEKRPTVLVDARGCATSPG
. . : :. . . : . : .