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VRDDADAGAVRLTRDDAVLHITLDRPSRRNSLSRTMIGTLVDTLTEAASDDSLRAIHLTGVGKDFCAGSD WVATNSGGGKPRPGNLLRRVPHQANRVVELLATIQLPVVCTVRGWAVGLGCNLALAADFTVATPEANLWE PFIDRGFSPDSGATWLLPRLAGVARAKRMLLLGEKVTGADAADWGLIHQAVPQDEIAGVAEDLMHRLAAG PTVAIGLAKRSIHYGMHATLPQSMDHELSDLELACRTSDFKEGLAAFRDRRAPGFTGR
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_4359 | - | - | 100% (268) | enoyl-CoA hydratase/isomerase |
| M. gilvum PYR-GCK | Mflv_2444 | - | 1e-37 | 36.88% (263) | enoyl-CoA hydratase/isomerase |
| M. gilvum PYR-GCK | Mflv_2125 | - | 2e-37 | 34.34% (265) | enoyl-CoA hydratase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1173c | echA11 | 1e-38 | 35.66% (258) | enoyl-CoA hydratase |
| M. tuberculosis H37Rv | Rv1141c | echA11 | 1e-38 | 35.66% (258) | enoyl-CoA hydratase |
| M. leprae Br4923 | MLBr_01241 | - | 6e-26 | 33.47% (251) | enoyl-CoA hydratase |
| M. abscessus ATCC 19977 | MAB_0905 | - | 1e-35 | 35.06% (251) | putative enoyl-CoA hydratase/isomerase |
| M. marinum M | MMAR_4022 | echA10_1 | 3e-98 | 65.90% (261) | enoyl-CoA hydratase EchA10_1 |
| M. avium 104 | MAV_1583 | - | 1e-102 | 68.46% (260) | enoyl-CoA hydratase/isomerase family protein |
| M. smegmatis MC2 155 | MSMEG_2220 | - | 1e-110 | 73.95% (261) | enoyl-CoA hydratase/isomerase |
| M. thermoresistible (build 8) | TH_2905 | - | 1e-102 | 67.69% (260) | PUTATIVE enoyl-CoA hydratase/isomerase |
| M. ulcerans Agy99 | MUL_3887 | echA10_1 | 4e-98 | 65.90% (261) | enoyl-CoA hydratase EchA10_1 |
| M. vanbaalenii PYR-1 | Mvan_1985 | - | 1e-125 | 82.46% (268) | enoyl-CoA hydratase/isomerase |
CLUSTAL 2.0.9 multiple sequence alignment
Mb1173c|M.bovis_AF2122/97 --------MPDSGIAALTPVTGLNVTLTDRVLSVRINRPSSLNSLTVPIL
Rv1141c|M.tuberculosis_H37Rv --------MPDSGIAALTPVTGLNVTLTDRVLSVRINRPSSLNSLTVPIL
Mflv_4359|M.gilvum_PYR-GCK --------MRDD-----ADAGAVRLTRDDAVLHITLDRPSRRNSLSRTMI
Mvan_1985|M.vanbaalenii_PYR-1 --------MRD-------DAGAVRVVRDDAVLRITLDRPTRRNSLSHAMI
MSMEG_2220|M.smegmatis_MC2_155 --------MALERPGLLVSDGSVTVTRDGAVLRIVLDRPSRRNSLDHTMV
TH_2905|M.thermoresistible__bu ----------------------VTVRRDGTVVRLTLDRPDRRNSLSPTMV
MMAR_4022|M.marinum_M ---------MSLEADSAGPEGSVTSRRDGTLLRITLDRPSRRNSLTQNMI
MUL_3887|M.ulcerans_Agy99 ---------MSLEADSAGPEGSVTSRRDGTLLRITLDRPSRRNSLTRNMI
MAV_1583|M.avium_104 ----------------------MAVHRQGAVLRLTLDRPSRRNALTQLMI
MAB_0905|M.abscessus_ATCC_1997 -------------MTQTAPAAVAYSVNHAGVAAIVLDRPEASNALDRTMK
MLBr_01241|M.leprae_Br4923 MSQTDASCTIAELPYRSVTDLVVLDFPRPEVALITLNRPGRMNSMALDLM
: : ::** *:: :
Mb1173c|M.bovis_AF2122/97 TGIADTLERAAADPVVKVVRLGGVGRGFSSGVSMSVDDVWGGGPPTA---
Rv1141c|M.tuberculosis_H37Rv TGIADTLERAAADPVVKVVRLGGVGRGFSSGVSMSVDDVWGGGPPTA---
Mflv_4359|M.gilvum_PYR-GCK GTLVDTLTEAASDDSLRAIHLTGVGKDFCAGSDWVATNSGGG-KPRPGNL
Mvan_1985|M.vanbaalenii_PYR-1 DDLVGTLTSAASDDSVRAIHLTGAGDDFCSGADWVTTNSSDR-KPRPGNL
MSMEG_2220|M.smegmatis_MC2_155 SELVTTLTAAASDDSLRAVSLSGAGEHFCTGSDWVATNSSGH-RPRTGDL
TH_2905|M.thermoresistible__bu DTLIRTLTSAATDDGLRAVLIEGAGDTFCSGSDWVATNESGSDRPRTGHL
MMAR_4022|M.marinum_M EMLLDTLGGAATDDSLRAILIRGAGADFCAGADWVAAS-TGTQRPRTGDL
MUL_3887|M.ulcerans_Agy99 EMLLDTLGGAATDDSLRAILIRGAAADFCAGADWVAAS-TGTQRHRTGDL
MAV_1583|M.avium_104 ATLVDALTAAASDDSLRVVHIVGAGDDFCAGADWVAVNDPGGPRPRAGDL
MAB_0905|M.abscessus_ATCC_1997 TELLQALLAAGGDPAVRAVVMSAAGKNFCVGQDLAEHVEALRDDPAH--A
MLBr_01241|M.leprae_Br4923 KSLKQVLKRITYDHSVRVVVLTGAGRGFCSGADQKFTAPVPQVEGLTQPV
: .* * ::.: : ... *. * .
Mb1173c|M.bovis_AF2122/97 ----IVEEANRAVRAVAALPHPVVAVVQGPAVGVAVSLALACDFILASDS
Rv1141c|M.tuberculosis_H37Rv ----IVEEANRAVRAVAALPHPVVAVVQGPAVGVAVSLALACDFILASDS
Mflv_4359|M.gilvum_PYR-GCK -LRRVPHQANRVVELLATIQLPVVCTVRGWAVGLGCNLALAADFTVATPE
Mvan_1985|M.vanbaalenii_PYR-1 -VRRIPHAANRVVELVATIQLPVVCTVRGWAVGLGANLALAADFTLATPE
MSMEG_2220|M.smegmatis_MC2_155 -VRRVPHAAHRIVELVATIQLPVVCTVRGWAVGLGCNLALAADFTVADAD
TH_2905|M.thermoresistible__bu -LRRLPHTGHRVIELVNTIHLPVVCAVRGWAVGLGCNLALAADFTVVADD
MMAR_4022|M.marinum_M -LRRIPHAAHRVIELLHTIHLPVVCGVQGWAAGLGANLALAADFTVASSD
MUL_3887|M.ulcerans_Agy99 -LRRIPHAAHRVIELLHTIHLPVVCGVQGWAAGLGANLALAADFTVATSD
MAV_1583|M.avium_104 -VRRIPHAAHRVIELVAGIQLPVVCSVRGWAVGFGCNLALAADFTVAAAD
MAB_0905|M.abscessus_ATCC_1997 -MDTVREHYNPVLEALDAIKVPVVVAINGACVGAGLGLALGADIRIAGQR
MLBr_01241|M.leprae_Br4923 RALRAMELLEEVILALRRLHQPVIAAINGPAIGGGLCLALAADVRVASTR
. . : : : **: :.* . * . ***..*. :.
Mb1173c|M.bovis_AF2122/97 AFFMLANTKVALMP-DGGASALVAAATGRIRAMRLALLAEQLPAREALAW
Rv1141c|M.tuberculosis_H37Rv AFFMLANTKVALMP-DGGASALVAAATGRIRAMRLALLAEQLPAREALAW
Mflv_4359|M.gilvum_PYR-GCK ANLWEPFIDRGFSP-DSGATWLLPRLAGVARAKRMLLLGEKVTGADAADW
Mvan_1985|M.vanbaalenii_PYR-1 ANLWEPFIDRGFSP-DSGSTWLLPRLAGVTRAKRMLLLGEKVTGADAADW
MSMEG_2220|M.smegmatis_MC2_155 ATFWEPFLSRGFSP-DSGATWLLPRLAGLTRAKQMLLLGEKVSGTEAADW
TH_2905|M.thermoresistible__bu AVLWEPFIDRGFTP-DSGSTWLLPRLVGLARAKRMLLLGEQISGADAVDW
MMAR_4022|M.marinum_M ATFWEPFVVRGFSP-DSGSTWLLPRLVGLARARRMLLLGEQVTAPEAADW
MUL_3887|M.ulcerans_Agy99 ATFWEPFVVRGFSP-DSGSTWLLPRLVGLARARRMLLLGEQVTAPEAADW
MAV_1583|M.avium_104 AVFWEPFVERGFSP-DSGSTWLLARLVGLARARRMLLLGEKVGGRDAADW
MAB_0905|M.abscessus_ATCC_1997 AKFGTAFTGIGLAA-DSALSASLPRLIGASRATAMFLLGDTIDAPTAHTW
MLBr_01241|M.leprae_Br4923 AYFRAAGINNGLSASELGLSYLLPRAVGSSRAFEIMLSGRDVGAEEAEQI
* : . .: . : . : :. * ** : * . : . *
Mb1173c|M.bovis_AF2122/97 GLISAVYPDSDFEAEVDKVISRLLAGPALAFAQAKNAIN--AAALTELEP
Rv1141c|M.tuberculosis_H37Rv GLISAVYPDSDFEAEVDKVISRLLAGPALAFAQAKNAIN--AAALTELEP
Mflv_4359|M.gilvum_PYR-GCK GLIHQAVPQDEIAGVAEDLMHRLAAGPTVAIGLAKRSIH--YGMHATLPQ
Mvan_1985|M.vanbaalenii_PYR-1 GLIHQAVPADEIDAAAEELVTRLASGPTVAIGLAKQAIN--YGMHATLPQ
MSMEG_2220|M.smegmatis_MC2_155 GLIHGAVPAAELETAAEDLIDRLASGPTVAIGLAKQAIA--FGQHATLIQ
TH_2905|M.thermoresistible__bu GLVHASVPAADVDRTATDLAARLAGGPTVAIGLAKHALN--FSQQATLPQ
MMAR_4022|M.marinum_M GLIHQVVDATALDSAVDELLTRLARGPTVAIGLAKQALN--HGQHATLTE
MUL_3887|M.ulcerans_Agy99 GLIHQVVDATDLDSAVDELLTRLARGPTVAIGLAKQALN--HGQHATLTE
MAV_1583|M.avium_104 GLIHRAVGGAELDDAAEELVGRLAAGPTAALGLAKQALS--FGQHATLSQ
MAB_0905|M.abscessus_ATCC_1997 GLVHEVVDEGSPADVANSVAGRLAGGPTAAFSEVKELLR--RNAVAPLGD
MLBr_01241|M.leprae_Br4923 GLVSYRVSDDRLLDTCYSIAARMATFSRSGTELTKRALWGGLDAASLDKH
**: .: *: . . .*. : :
Mb1173c|M.bovis_AF2122/97 TFARELDGQEVLLRTHDFAEGAAAFLQRRTPNFTGS--------
Rv1141c|M.tuberculosis_H37Rv TFARELDGQEVLLRTHDFAEGAAAFLQRRTPNFTGS--------
Mflv_4359|M.gilvum_PYR-GCK SMDHELSDLELACRTSDFKEGLAAFRDRRAPGFTGR--------
Mvan_1985|M.vanbaalenii_PYR-1 SMAHELASLELACRTADFKEGLAAFRARRAPDFEGR--------
MSMEG_2220|M.smegmatis_MC2_155 SMNQELSNLELSCRTHDFKEGLAAFRERRDPDFQGR--------
TH_2905|M.thermoresistible__bu AMDNELYNVELSCRTADFKEGLAAFRDRRAPEFQGR--------
MMAR_4022|M.marinum_M SMTHELFSLELTCRTSDFKEGLTAFRQHRTPKFEGR--------
MUL_3887|M.ulcerans_Agy99 SMTHELFNLELTCRTSDFKEGLTAFRQHRTPKFEGR--------
MAV_1583|M.avium_104 SLTQELFNLELSCRTSDFKEGLEAFRQRRDPDFRGR--------
MAB_0905|M.abscessus_ATCC_1997 VLEREASAQQRLGASRDHSAAVEAFLAKDKPVFVGR--------
MLBr_01241|M.leprae_Br4923 MQSESLAQLFIALHTSNFEEAAAPCTEKRPTVLVDARGCATSPG
.. : :. . . : . : .