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TNVLTSNDGPVRIVTLNRPGVRNAIDIPLRIELAEVLEAADADESVRSIVLTGAGRVFCSGGDISTMQRM ESEDAKHRADLAQRVIRAIWNTAKPVVAAVEGAAFGAGAALALACDRVVAARDARFATTFTNVGLAGDMG TFVSLPRRVGIARARQMLLLPQPIGAEEAAALGMVDALTDPGHTLEAATRDAQNLAAGPAEAFGVIKALL AIAPTLHPLDALEEEASYQARLFGTDDFVEGVAAFRDKRRPSFGQRQGVRP*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_5085 | - | - | 100% (262) | enoyl-CoA hydratase |
| M. avium 104 | MAV_2601 | - | 6e-46 | 42.58% (256) | enoyl-CoA hydratase/isomerase |
| M. avium 104 | MAV_1884 | - | 1e-39 | 40.89% (247) | enoyl-CoA isomerase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1174c | echA10 | 4e-34 | 37.55% (253) | enoyl-CoA hydratase |
| M. gilvum PYR-GCK | Mflv_2444 | - | 1e-41 | 42.13% (254) | enoyl-CoA hydratase/isomerase |
| M. tuberculosis H37Rv | Rv1142c | echA10 | 4e-34 | 37.55% (253) | enoyl-CoA hydratase |
| M. leprae Br4923 | MLBr_01241 | - | 2e-27 | 35.60% (250) | enoyl-CoA hydratase |
| M. abscessus ATCC 19977 | MAB_0905 | - | 1e-38 | 38.58% (254) | putative enoyl-CoA hydratase/isomerase |
| M. marinum M | MMAR_4022 | echA10_1 | 9e-33 | 36.54% (260) | enoyl-CoA hydratase EchA10_1 |
| M. smegmatis MC2 155 | MSMEG_2220 | - | 2e-36 | 37.16% (261) | enoyl-CoA hydratase/isomerase |
| M. thermoresistible (build 8) | TH_3666 | - | 7e-45 | 70.23% (131) | PUTATIVE enoyl-CoA hydratase |
| M. ulcerans Agy99 | MUL_0985 | echA10 | 2e-32 | 36.99% (246) | enoyl-CoA hydratase |
| M. vanbaalenii PYR-1 | Mvan_4207 | - | 8e-42 | 43.20% (250) | enoyl-CoA hydratase/isomerase |
CLUSTAL 2.0.9 multiple sequence alignment
MAV_5085|M.avium_104 --------------MTN-----VLTSNDGPVRIVTLNRPGVRNAIDIPLR
TH_3666|M.thermoresistible__bu --------------MTGHDDAPVLIADDGAVRIVTLNRPQVRNAIDIPLR
Mflv_2444|M.gilvum_PYR-GCK --------------MAD--TEVLLSSDRDGVRTLTLNRPHRRNALDARLW
Mvan_4207|M.vanbaalenii_PYR-1 --------------MVD--DQVLLSTDRDGVRTLTLNRPERRNALDARLW
Mb1174c|M.bovis_AF2122/97 --------MSNYRIDTRTIVPGLAVTLADGVLSVTIDRPESLNSLTKPVL
Rv1142c|M.tuberculosis_H37Rv --------MSNYRIDTRTIVPGLAVTLADGVLSVTIDRPESLNSLTKPVL
MUL_0985|M.ulcerans_Agy99 --------MPDTRIETLAPVAGLEVKLRGGVLSVTIDRPESLNSLTPEVM
MMAR_4022|M.marinum_M --------MSLEADSAGP-EGSVTSRRDGTLLRITLDRPSRRNSLTQNMI
MSMEG_2220|M.smegmatis_MC2_155 --------MALERPGLLVSDGSVTVTRDGAVLRIVLDRPSRRNSLDHTMV
MAB_0905|M.abscessus_ATCC_1997 -------------MTQTAPAAVAYSVNHAGVAAIVLDRPEASNALDRTMK
MLBr_01241|M.leprae_Br4923 MSQTDASCTIAELPYRSVTDLVVLDFPRPEVALITLNRPGRMNSMALDLM
: :.::** *:: :
MAV_5085|M.avium_104 IELAEVLEAADADESVRSIVLTGAGRVFCSGGDISTMQRMESEDAKHRAD
TH_3666|M.thermoresistible__bu IALAEALENADSDPKVRAIVLTGAGTAFCSGGDISTMKRTPEAEATERIQ
Mflv_2444|M.gilvum_PYR-GCK VELADALRALKREQDVRALVLTGAGGAFCSGADIGTGEQIHP---RYKLD
Mvan_4207|M.vanbaalenii_PYR-1 VELADALRDLKRDHDVRALVLTGAGGAFCSGADIGTGEQIHP---RYKLD
Mb1174c|M.bovis_AF2122/97 AGMADAIEGAATDPRVKVVRLGGAGRGFSSGGAISVDDVWASGPPTDTVA
Rv1142c|M.tuberculosis_H37Rv AGMADAIEGAATDPRVKVVRLGGAGRGFSSGGAISVDDVWASGPPTDTVA
MUL_0985|M.ulcerans_Agy99 AGIADAMEAAATDSRVRVVRLGGTGRGFSSGAGMSAQDMGR-KTSTSSLT
MMAR_4022|M.marinum_M EMLLDTLGGAATDDSLRAILIRGAGADFCAGADWVAASTGTQRPRTGDLL
MSMEG_2220|M.smegmatis_MC2_155 SELVTTLTAAASDDSLRAVSLSGAGEHFCTGSDWVATNSSGHRPRTGDLV
MAB_0905|M.abscessus_ATCC_1997 TELLQALLAAGGDPAVRAVVMSAAGKNFCVG-QDLAEHVEALRDDPAHAM
MLBr_01241|M.leprae_Br4923 KSLKQVLKRITYDHSVRVVVLTGAGRGFCSGADQKFTAPVPQVEGLTQPV
: .: : :: : : .:* *. *
MAV_5085|M.avium_104 -------LAQRVIRAIWNTAKPVVAAVEGAAFGAGAALALACDRVVAARD
TH_3666|M.thermoresistible__bu -------LAQRVIRAIWQTSKPVLAAVEGSAFGAGVALAAACDRVVAAPX
Mflv_2444|M.gilvum_PYR-GCK -------RLTDVALALHELAIPTIAKVTGIAVGAGWNLALGCDLVVATPE
Mvan_4207|M.vanbaalenii_PYR-1 -------RLTDVALALHELAVPTIAKVTGIAVGAGWNLALGCDLVVATPE
Mb1174c|M.bovis_AF2122/97 -------EANRTVRAIVALPQPVVAVVQGPTVGCGVSLALACDLVLASDN
Rv1142c|M.tuberculosis_H37Rv -------EANRTVRAIVALPQPVVAVVQGPTVGCGVSLALACDLVLASDN
MUL_0985|M.ulcerans_Agy99 -------EINRAVRAITALPHPVVAVVHGPAAGVGVSLALACDLVLASES
MMAR_4022|M.marinum_M RRI--PHAAHRVIELLHTIHLPVVCGVQGWAAGLGANLALAADFTVASSD
MSMEG_2220|M.smegmatis_MC2_155 RRV--PHAAHRIVELVATIQLPVVCTVRGWAVGLGCNLALAADFTVADAD
MAB_0905|M.abscessus_ATCC_1997 DTV--REHYNPVLEALDAIKVPVVVAINGACVGAGLGLALGADIRIAGQR
MLBr_01241|M.leprae_Br4923 RALRAMELLEEVILALRRLHQPVIAAINGPAIGGGLCLALAADVRVASTR
: *.: : * * * ** ..* :*
MAV_5085|M.avium_104 ARFATTFTNVGLAGDM-GTFVSLPRRVGIARARQMLLLPQPIGAEEAAAL
TH_3666|M.thermoresistible__bu X----------XSG---GTFESVS-----AHSPQRLHTHRSRSSPDTAA-
Mflv_2444|M.gilvum_PYR-GCK SRFCQIFSKRGLSVDL-GGSWLLPKTVGLQQAKRLVLLADMIDADEAHGL
Mvan_4207|M.vanbaalenii_PYR-1 SRFCQIFSKRGLSVDL-GGSWLLPRIVGLQQAKRLVLLAEMIGADEARDL
Mb1174c|M.bovis_AF2122/97 AFFMLAHTNVGLMPDG-GASALVQAAIGRIRAMHMALLPDRVPAAEALSW
Rv1142c|M.tuberculosis_H37Rv AFFMLAHTNVGLMPDG-GASALVQAAIGRIRAMHMALLPDRVPAAEALSW
MUL_0985|M.ulcerans_Agy99 AYFLLAFTKIGLMPDG-GASALIAAVIGRIRAMRMALLPERLPATEALSY
MMAR_4022|M.marinum_M ATFWEPFVVRGFSPDS-GSTWLLPRLVGLARARRMLLLGEQVTAPEAADW
MSMEG_2220|M.smegmatis_MC2_155 ATFWEPFLSRGFSPDS-GATWLLPRLAGLTRAKQMLLLGEKVSGTEAADW
MAB_0905|M.abscessus_ATCC_1997 AKFGTAFTGIGLAADS-ALSASLPRLIGASRATAMFLLGDTIDAPTAHTW
MLBr_01241|M.leprae_Br4923 AYFRAAGINNGLSASELGLSYLLPRAVGSSRAFEIMLSGRDVGAEEAEQI
. : :: . :
MAV_5085|M.avium_104 GMVDALTDPGHTLEAATRDAQNLAAGPAEAFGVIKALLAIAPTLHPLDAL
TH_3666|M.thermoresistible__bu --------------------------------------------------
Mflv_2444|M.gilvum_PYR-GCK GLVTWVKPAGEIDGFIDELADRLAAGPPFALAQSKALLNDGATATLREAL
Mvan_4207|M.vanbaalenii_PYR-1 GLVTWVKPSGEIDAFVDDLADRLAGGPPFALAQSKALLNDGANATLREAL
Mb1174c|M.bovis_AF2122/97 GLVSAVYPAADFDAEVDKLISRLLAGPALAIAKTKNAINAATLTELAPTL
Rv1142c|M.tuberculosis_H37Rv GLVSAVYPAADFDAEVDKLISRLLAGPALAIAKTKNAINAATLTELAPTL
MUL_0985|M.ulcerans_Agy99 GLVSAVYPVADFQNEVDAVISRLLSGPAVAFAKTKNSINAATLTELDRTL
MMAR_4022|M.marinum_M GLIHQVVDATALDSAVDELLTRLARGPTVAIGLAKQALNHGQHATLTESM
MSMEG_2220|M.smegmatis_MC2_155 GLIHGAVPAAELETAAEDLIDRLASGPTVAIGLAKQAIAFGQHATLIQSM
MAB_0905|M.abscessus_ATCC_1997 GLVHEVVDEGSPADVANSVAGRLAGGPTAAFSEVKELLRRNAVAPLGDVL
MLBr_01241|M.leprae_Br4923 GLVSYRVSDDRLLDTCYSIAARMATFSRSGTELTKRALWGGLDAASLDKH
MAV_5085|M.avium_104 EE--EASYQARLFGTDDFVEGVAAFRDKRRPSFGQRQGVRP--------
TH_3666|M.thermoresistible__bu -------------------------------------------------
Mflv_2444|M.gilvum_PYR-GCK AN--EARAQPGNFATADSAEAYAAFAAKRDPEFSGAWALYEQPEEQR--
Mvan_4207|M.vanbaalenii_PYR-1 AN--EARAQPGNFATADSVEAYAAFAAKREPEFTGAWVQYEKPTQKDEE
Mb1174c|M.bovis_AF2122/97 LR--ELDGQALLLRTDDFAEGATAFQQRRTPMFTGR-------------
Rv1142c|M.tuberculosis_H37Rv LR--ELDGQALLLRTDDFAEGATAFQQRRTPMFTGR-------------
MUL_0985|M.ulcerans_Agy99 DR--EFQGQSALLRSPDFAEGARAFQQRRTPTFTDS-------------
MMAR_4022|M.marinum_M TH--ELFSLELTCRTSDFKEGLTAFRQHRTPKFEGR-------------
MSMEG_2220|M.smegmatis_MC2_155 NQ--ELSNLELSCRTHDFKEGLAAFRERRDPDFQGR-------------
MAB_0905|M.abscessus_ATCC_1997 ER--EASAQQRLGASRDHSAAVEAFLAKDKPVFVGR-------------
MLBr_01241|M.leprae_Br4923 MQSESLAQLFIALHTSNFEEAAAPCTEKRPTVLVDARGCATSPG-----