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M. tuberculosis H37Rv Rv1142c (echA10)

annotation: enoyl-CoA hydratase
coordinates: 1269152 - 1269958
length: 268

SNYRIDTRTIVPGLAVTLADGVLSVTIDRPESLNSLTKPVLAGMADAIEGAATDPRVKVVRLGGAGRGFS
SGGAISVDDVWASGPPTDTVAEANRTVRAIVALPQPVVAVVQGPTVGCGVSLALACDLVLASDNAFFMLA
HTNVGLMPDGGASALVQAAIGRIRAMHMALLPDRVPAAEALSWGLVSAVYPAADFDAEVDKLISRLLAGP
ALAIAKTKNAINAATLTELAPTLLRELDGQALLLRTDDFAEGATAFQQRRTPMFTGR*

Operon Prediction Model: Genebank

Paralogs

species id gene e-value identity (len) annotation
M. tuberculosis H37Rv Rv1142c echA10 - 100% (268) enoyl-CoA hydratase
M. tuberculosis H37Rv Rv1141c echA11 e-103 72.28% (267) enoyl-CoA hydratase
M. tuberculosis H37Rv Rv1070c echA8 2e-26 31.84% (245) enoyl-CoA hydratase

Closest Orthologs (e-value cutoff: 1e-4)

species id gene e-value identity (len) annotation
M. bovis AF2122 / 97 Mb1174c echA10 1e-148 100.00% (268) enoyl-CoA hydratase
M. gilvum PYR-GCK Mflv_2125 - 1e-78 60.39% (255) enoyl-CoA hydratase
M. leprae Br4923 MLBr_02402 - 3e-25 31.97% (244) enoyl-CoA hydratase
M. abscessus ATCC 19977 MAB_4570c - 1e-44 40.47% (257) enoyl-CoA hydratase/isomerase
M. marinum M MMAR_4309 echA10 2e-96 69.92% (266) enoyl-CoA hydratase EchA10
M. avium 104 MAV_1283 - 1e-104 72.22% (270) enoyl-CoA hydratase
M. smegmatis MC2 155 MSMEG_5185 - 3e-85 64.06% (256) enoyl-CoA hydratase
M. thermoresistible (build 8) TH_2638 - 3e-82 62.65% (257) PUTATIVE enoyl-CoA hydratase PaaB
M. ulcerans Agy99 MUL_0985 echA10 8e-97 69.92% (266) enoyl-CoA hydratase
M. vanbaalenii PYR-1 Mvan_4579 - 8e-87 64.34% (258) enoyl-CoA hydratase

CLUSTAL 2.0.9 multiple sequence alignment


Rv1142c|M.tuberculosis_H37Rv        -----MSNYR------IDTRTIVPGLAVTLADGVLSVTIDRPESLNSLTK
Mb1174c|M.bovis_AF2122/97           -----MSNYR------IDTRTIVPGLAVTLADGVLSVTIDRPESLNSLTK
MMAR_4309|M.marinum_M               -----MPDTR------IETLAPVAGLEVKLRGGVLSVTIDRPESLNSLTP
MUL_0985|M.ulcerans_Agy99           -----MPDTR------IETLAPVAGLEVKLRGGVLSVTIDRPESLNSLTP
MAV_1283|M.avium_104                -----MPSSA------IATLAPVAGLDVTLSDGVFSVTINRPDSLNSLTV
Mflv_2125|M.gilvum_PYR-GCK          -----MTATD--------AYQGIDHLTASLDGSVLTVTLNRPESLNSLTA
Mvan_4579|M.vanbaalenii_PYR-1       MKGTFMTTTDP----TTDAYEGIADLAVGLDDGVLTVTLNRPNSLNSLTA
TH_2638|M.thermoresistible__bu      -----MSSVT---------YPSIDDLRVALSDGVLTVTLNRPDSLNSLTA
MSMEG_5185|M.smegmatis_MC2_155      -----MTSTDASAETVTRDYPSIDDVSVSLTDGVLAVTLNRPDSLNSLNR
MAB_4570c|M.abscessus_ATCC_199      -----MSLDE-----------SVGAPDVAVDGGIMRVTFTRPDRMNALNG
MLBr_02402|M.leprae_Br4923          --------------------MKYDTILVDGYQRVGIITLNRPQALNALNS
                                                               .     :  :*: **: :*:*. 

Rv1142c|M.tuberculosis_H37Rv        PVLAGMADAIEGAATDPRVKVVRLGG--AGRGFSSGGAISVDDVWASGP-
Mb1174c|M.bovis_AF2122/97           PVLAGMADAIEGAATDPRVKVVRLGG--AGRGFSSGGAISVDDVWASGP-
MMAR_4309|M.marinum_M               EVMAGIADAMEAAATDSRVRVVRLGG--TGRGFSSGAGMSAQDMGRKTS-
MUL_0985|M.ulcerans_Agy99           EVMAGIADAMEAAATDSRVRVVRLGG--TGRGFSSGAGMSAQDMGRKTS-
MAV_1283|M.avium_104                PVITGIADAMEYAATDPEVKVVRIGG--AGRGFSSGAGISADDVSDGGG-
Mflv_2125|M.gilvum_PYR-GCK          PMLETFAVTLERAATDPRVRVVRIGG--AGRGFCSGAGISEEDHANPGAA
Mvan_4579|M.vanbaalenii_PYR-1       PMLQAFAATLERAAGDPRVRVVRIGG--AGRGFCSGAGISEEDHANPGAA
TH_2638|M.thermoresistible__bu      PMLQTLAEAVELAASDPRVKVIRLTG--AGRGFCAGAGISEDDQAARESG
MSMEG_5185|M.smegmatis_MC2_155      DMLDAVADAMEVAATDPAVRVVRLGG--AGRGFSSGAGISEEDQNAKG--
MAB_4570c|M.abscessus_ATCC_199      PATSGLIEALESIPGRDDVRVVVISGGAPGSAFSAGADVTELAAGSADLT
MLBr_02402|M.leprae_Br4923          QMMNEITNAAKELDIDPDVGAILITG--SPKVFAAGADIKEMASLTFTDA
                                         .  : :       * .: : *  .   *.:*. :.          

Rv1142c|M.tuberculosis_H37Rv        --PTDT--VAEANRTVRAIVALPQPVVAVVQGPTVGCGVSLALACDLVLA
Mb1174c|M.bovis_AF2122/97           --PTDT--VAEANRTVRAIVALPQPVVAVVQGPTVGCGVSLALACDLVLA
MMAR_4309|M.marinum_M               --TSS---LTEINRAVRAITALPHPVVAVVHGPAAGVGVSLALACDLVLA
MUL_0985|M.ulcerans_Agy99           --TSS---LTEINRAVRAITALPHPVVAVVHGPAAGVGVSLALACDLVLA
MAV_1283|M.avium_104                --VPPDEIILEINRLVRAIAALPHPVVAVVQGPAAGVGVSIALACDVVLA
Mflv_2125|M.gilvum_PYR-GCK          --GSPNDVLDAANRCIRAIANLPQPAVAVVQGAAAGVGVSLALACDVVLA
Mvan_4579|M.vanbaalenii_PYR-1       --GPPTDVLDGANRCIRAIANLPQPSVAVVQGAAAGVGVSLALACDVVIA
TH_2638|M.thermoresistible__bu      --GG-NALLDGANRSVTAIVNCPKPVVAVVPGAAAGVGVSLALACDVVLA
MSMEG_5185|M.smegmatis_MC2_155      --HDAAAVLDAANRAVAAIVALPKPVVAVVHGPAAGVGVSLALACDIVLA
MAB_4570c|M.abscessus_ATCC_199      PLQAAELTMDNAERLVRAVLNCPVPTIAEVTGVAAGIGASVGLACDLIYA
MLBr_02402|M.leprae_Br4923          -------FDADFFSAWGKLAAVRTPMIAAVAGYALGGGCELAMMCDLLIA
                                                      :     * :* * * : * * .:.: **:: *

Rv1142c|M.tuberculosis_H37Rv        SDNAFFMLAHTNVGLMPDGGASALVQAAIGRIRAMHMALLPDRVPAAEAL
Mb1174c|M.bovis_AF2122/97           SDNAFFMLAHTNVGLMPDGGASALVQAAIGRIRAMHMALLPDRVPAAEAL
MMAR_4309|M.marinum_M               SESAYFLLAFTKIGLMPDGGASALIAAAIGRIRAMRMALLPERLPATEAL
MUL_0985|M.ulcerans_Agy99           SESAYFLLAFTKIGLMPDGGASALIAAVIGRIRAMRMALLPERLPATEAL
MAV_1283|M.avium_104                SENAFFMLAFTKIGLMPDGGASALVAAAVGRIRAMQMALLPERLPAAEAL
Mflv_2125|M.gilvum_PYR-GCK          SEKSFFMLAFTKIGLMPDGAASALIAAAVGRIRAMRMALLAERITADEAY
Mvan_4579|M.vanbaalenii_PYR-1       SEKAFFMLAFTKIGLMPDGGASALIAAAVGRIRAMRMALLAERISAREAY
TH_2638|M.thermoresistible__bu      SEQAFFLLAFTKIGLMPDGGASALVAAAIGRIRAMRMALLAERISAAEAH
MSMEG_5185|M.smegmatis_MC2_155      SDQAFFLLAFTKIGLMPDGGASALVAAAIGRIRAMRLALLADRLTATDAY
MAB_4570c|M.abscessus_ATCC_199      ADTAFFLLAFANIGLMPDGGSSALVSASIGRVKANAMALLAQPLSATDAF
MLBr_02402|M.leprae_Br4923          ADTAKFGQPEIKLGVLPGMGGSQRLTRAIGKAKAMDLILTGRTIDAAEAE
                                    :: : *  .  ::*::*. ..*  :   :*: :*  : *    : * :* 

Rv1142c|M.tuberculosis_H37Rv        SWGLVSAVYPAADFDAEVDKLISRLLAGPALAIAKTKNAINAATLTELAP
Mb1174c|M.bovis_AF2122/97           SWGLVSAVYPAADFDAEVDKLISRLLAGPALAIAKTKNAINAATLTELAP
MMAR_4309|M.marinum_M               SYGLVSAVYPVADFQNEVDAVISRLLSGPAVAFAKTKDSINAATLTELDR
MUL_0985|M.ulcerans_Agy99           SYGLVSAVYPVADFQNEVDAVISRLLSGPAVAFAKTKNSINAATLTELDR
MAV_1283|M.avium_104                SWGLVTAVYPADEFEAEVDKVIARLLSGPAVAFAKTKLAINAATLTELDP
Mflv_2125|M.gilvum_PYR-GCK          AWGLVSQVYPADSLEAEAASVIETLATGPAVALRLTKDAINGATLTEVEN
Mvan_4579|M.vanbaalenii_PYR-1       DWGLVSSVHPAEEFDAEVDKVIATLVAGPAVALRKTKDAINAATLTELEA
TH_2638|M.thermoresistible__bu      QWGLVTGVYPADEFDAAVDKVISTLTNGPAVALRETKQAINAATLGELPD
MSMEG_5185|M.smegmatis_MC2_155      DWGLISAVYPADEFDAAVDKVLAKLRNGPAVALRKTKQAINEATLTELDD
MAB_4570c|M.abscessus_ATCC_199      AAGLVNEALPGDQLRERVDKTARRLAHGSRRAMQLTKEAMNAVSLKLFDE
MLBr_02402|M.leprae_Br4923          RSGLVSRVVLADDLLPEAKAVATTISQMSRSATRMAKEAVNRSFESTLAE
                                      **:. .    .:   .      :   .  *   :* ::*      .  

Rv1142c|M.tuberculosis_H37Rv        TLLRELDGQALLLRTDDFAEGATAFQQRRTPMFTGR
Mb1174c|M.bovis_AF2122/97           TLLRELDGQALLLRTDDFAEGATAFQQRRTPMFTGR
MMAR_4309|M.marinum_M               TLDREFQGQSALLRSPDFAEGARAFQQRRTPTFTDS
MUL_0985|M.ulcerans_Agy99           TLDREFQGQSALLRSPDFAEGARAFQQRRTPTFTDS
MAV_1283|M.avium_104                ALQREFDGQSVLLKSPDFVEGATAFQQRRTPNFTDR
Mflv_2125|M.gilvum_PYR-GCK          ALERETKGQLRLLHSDDFREGTKAFQQRRAAKFTDV
Mvan_4579|M.vanbaalenii_PYR-1       ALERETAGQLVLLKSADFREGTHAFQQRRVAKFTDS
TH_2638|M.thermoresistible__bu      AIKRETEGQVRLLGSNDFREGTQAFQQKRAPKFTDV
MSMEG_5185|M.smegmatis_MC2_155      AIAREREGQLELLVANDFREGAQAFQQNRRPEFTDQ
MAB_4570c|M.abscessus_ATCC_199      AIARERDGQIELLISPDAHEGFAAFLEGRRPNFS--
MLBr_02402|M.leprae_Br4923          GLLHERRLFHSTFVTDDQSEGMAAFIEKRAPQFTHR
                                     : :*       : : *  **  ** : * . *:

species	id	gene	e-value	identity (len)	annotation
M. tuberculosis H37Rv	Rv1142c	echA10	-	100% (268)	enoyl-CoA hydratase
M. tuberculosis H37Rv	Rv1141c	echA11	e-103	72.28% (267)	enoyl-CoA hydratase
M. tuberculosis H37Rv	Rv1070c	echA8	2e-26	31.84% (245)	enoyl-CoA hydratase