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M. bovis AF2122 / 97 Mb1183 (-)

annotation: transcriptional regulatory protein
coordinates: 1281027 - 1281392
length: 121

VELRDWLRVDVKAGKPLFDQLRTQVIDGVRAGALPPGTRLPTVRDLAGQLGVAANTVARAYRELESAAIV
ETRGRFGTFISRFDPTDAAMAAAAKEYVGVARALGLTKSDAMRYLTHVPDD
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb1183--100% (121)transcriptional regulatory protein
M. bovis AF2122 / 97Mb0505-4e-0630.65% (62) GntR family transcriptional regulator
M. bovis AF2122 / 97Mb0601-9e-0640.35% (57) GntR family transcriptional regulator

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. gilvum PYR-GCKMflv_2135-3e-4167.54% (114) regulatory protein GntR, HTH
M. tuberculosis H37RvRv1152-6e-65100.00% (121) transcriptional regulatory protein
M. leprae Br4923-----
M. abscessus ATCC 19977MAB_3582-1e-0844.64% (56) GntR family transcriptional regulator
M. marinum MMMAR_4301-3e-6297.52% (121) transcriptional regulatory protein
M. avium 104MAV_1290-4e-5583.47% (121) regulatory protein GntR, HTH
M. smegmatis MC2 155MSMEG_5174-2e-3961.02% (118) regulatory protein GntR, HTH
M. thermoresistible (build 8)TH_3932-2e-0740.00% (70) PUTATIVE transcriptional regulator, GntR family
M. ulcerans Agy99MUL_0993-1e-5994.21% (121) transcriptional regulatory protein
M. vanbaalenii PYR-1Mvan_4569-1e-4168.42% (114) regulatory protein GntR, HTH

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_2135|M.gilvum_PYR-GCK          ---MGDLGDWVKVDPHAARPLFDQLRTQIIAGVRDGELAPGTRLPTVREL
Mvan_4569|M.vanbaalenii_PYR-1       ---MAELGDWVRVDPHAARPLFDQLRTQIIAGIRDGELTPGTRLPTVREL
MSMEG_5174|M.smegmatis_MC2_155      ------MGDWVSIDPDSDKPLFDQLRVQIIDGIRDGRLSPGTRLPTVREL
Mb1183|M.bovis_AF2122/97            ----MELRDWLRVDVKAGKPLFDQLRTQVIDGVRAGALPPGTRLPTVRDL
Rv1152|M.tuberculosis_H37Rv         ----MELRDWLRVDVKAGKPLFDQLRTQVIDGVRAGALPPGTRLPTVRDL
MMAR_4301|M.marinum_M               ----MELRDWLRVDVKAGKPLFDQLRTQVIDGVRAGALPPGTRLPTVRDL
MUL_0993|M.ulcerans_Agy99           ----MELRDWLRVDVKAGKPLFDQLGTQVIDGVRAGALPPGTRLPTVRDL
MAV_1290|M.avium_104                ----MELGDWLRVDMKAGKPLFDQLRTQVIEGVREGALPPGTRLPTVREL
TH_3932|M.thermoresistible__bu      MTRTATPMRSTTINRFADRPLYRQLS-EVLEARLIERARPGDRLPSEAEL
MAB_3582|M.abscessus_ATCC_1997      ----------MRIRRHAA------VADGIAEQIRTGALPAGTRLPTHRAL
                                                :   :       :   :          .* ***:   *

Mflv_2135|M.gilvum_PYR-GCK          AGQVNLAVNTVARAYRELEAAGILETRGRFGTFVARAD------------
Mvan_4569|M.vanbaalenii_PYR-1       AGQINLAVNTVARAYRELEAAGILETRGRFGTYVARSD------------
MSMEG_5174|M.smegmatis_MC2_155      ATHVGLAVNTVARSYRELEAAGVLETRGRFGTFVARAD------------
Mb1183|M.bovis_AF2122/97            AGQLGVAANTVARAYRELESAAIVETRGRFGTFISRFD------------
Rv1152|M.tuberculosis_H37Rv         AGQLGVAANTVARAYRELESAAIVETRGRFGTFISRFD------------
MMAR_4301|M.marinum_M               AGQLGVAANTVARAYRELESAAIVETRGRFGTFISRFD------------
MUL_0993|M.ulcerans_Agy99           VGQLGVAANTVARAYRELESVAIVETRGRCGTFISRFD------------
MAV_1290|M.avium_104                AGQLGVAVNTVARAYRELESAAIIETRGRFGTFVARYD------------
TH_3932|M.thermoresistible__bu      SGQFGVNRLTVRRALHELAQRGIIETVHGRGSFVARQP------------
MAB_3582|M.abscessus_ATCC_1997      AARHGIAVATASRVYRDLTASGLVVGEPGRGTFVRDLSGFAGLEPARLSA
                                      : .:   *. *  ::*   .::      *:::                

Mflv_2135|M.gilvum_PYR-GCK          --------PADVAMATAANTYVSAARALG---------------------
Mvan_4569|M.vanbaalenii_PYR-1       --------PADAAMATAAHTYVATARALG---------------------
MSMEG_5174|M.smegmatis_MC2_155      --------PADAAMAAAANSFAEAARSLG---------------------
Mb1183|M.bovis_AF2122/97            --------PTDAAMAAAAKEYVGVARALG---------------------
Rv1152|M.tuberculosis_H37Rv         --------PTDAAMAAAAKEYVGVARALG---------------------
MMAR_4301|M.marinum_M               --------PTDAAMAAAAKEYVEVARALG---------------------
MUL_0993|M.ulcerans_Agy99           --------PTDAAMAAAAKEYVEVARALG---------------------
MAV_1290|M.avium_104                --------PTDAAMAAAAREYVRVARGLG---------------------
TH_3932|M.thermoresistible__bu      --------VRYRLSATRDASFTRGMRELGHPVRIEVLGAETTRCRRLRTE
MAB_3582|M.abscessus_ATCC_1997      GQRTADLSFNQPLSTGQDDELRQALRGLAAEG----DLTSLLYQQPPGGR
                                                  :          * *.                     

Mflv_2135|M.gilvum_PYR-GCK          ------VEKDEALRYIESAFG-----------------------------
Mvan_4569|M.vanbaalenii_PYR-1       ------VGKGEALRYVETAFG-----------------------------
MSMEG_5174|M.smegmatis_MC2_155      ------ISRDDALRYIESALD-----------------------------
Mb1183|M.bovis_AF2122/97            ------LTKSDAMRYLTHVPDD----------------------------
Rv1152|M.tuberculosis_H37Rv         ------LTKSDAMRYLTHVPDD----------------------------
MMAR_4301|M.marinum_M               ------LTKSDAIRYLTAVPDD----------------------------
MUL_0993|M.ulcerans_Agy99           ------LTKSDAIRYLTAVPDD----------------------------
MAV_1290|M.avium_104                ------LDKADAVRYIESVPDE----------------------------
TH_3932|M.thermoresistible__bu      LHTAGEVLTTTTLRHVDGQPWSVSVTSIALDRFPGIAQQWSGSTSLFDFL
MAB_3582|M.abscessus_ATCC_1997      SRDRAAIASYLLGRGIDVAPHSVLITGGAQQGLDALLVALAEPRAVVAVD
                                          :      * :                                  

Mflv_2135|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_4569|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_5174|M.smegmatis_MC2_155      --------------------------------------------------
Mb1183|M.bovis_AF2122/97            --------------------------------------------------
Rv1152|M.tuberculosis_H37Rv         --------------------------------------------------
MMAR_4301|M.marinum_M               --------------------------------------------------
MUL_0993|M.ulcerans_Agy99           --------------------------------------------------
MAV_1290|M.avium_104                --------------------------------------------------
TH_3932|M.thermoresistible__bu      WQTFG---VRMRRAYRSFSAVLADLA--EAQHLGLRTGAPVLEMRGLNVD
MAB_3582|M.abscessus_ATCC_1997      ALTYPGIRMLATARHLDLAAVRADTTGMDIDHLEWLCGQRPISMLYLIPT
                                                                                      

Mflv_2135|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_4569|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_5174|M.smegmatis_MC2_155      --------------------------------------------------
Mb1183|M.bovis_AF2122/97            --------------------------------------------------
Rv1152|M.tuberculosis_H37Rv         --------------------------------------------------
MMAR_4301|M.marinum_M               --------------------------------------------------
MUL_0993|M.ulcerans_Agy99           --------------------------------------------------
MAV_1290|M.avium_104                --------------------------------------------------
TH_3932|M.thermoresistible__bu      QHGAPVAVVRHRFRGDRVELTVDLA-------------------------
MAB_3582|M.abscessus_ATCC_1997      LHNPLGYILGASARQRIAALAARHDFHIIEDATYAFLEPAAPPPVQTVAP
                                                                                      

Mflv_2135|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_4569|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_5174|M.smegmatis_MC2_155      --------------------------------------------------
Mb1183|M.bovis_AF2122/97            --------------------------------------------------
Rv1152|M.tuberculosis_H37Rv         --------------------------------------------------
MMAR_4301|M.marinum_M               --------------------------------------------------
MUL_0993|M.ulcerans_Agy99           --------------------------------------------------
MAV_1290|M.avium_104                --------------------------------------------------
TH_3932|M.thermoresistible__bu      --------------------------------------------------
MAB_3582|M.abscessus_ATCC_1997      ERTFYIGSMSKNLASGLRIGYVVAPLARRPALIRSLRATSWGASSIASAL
                                                                                      

Mflv_2135|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_4569|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_5174|M.smegmatis_MC2_155      --------------------------------------------------
Mb1183|M.bovis_AF2122/97            --------------------------------------------------
Rv1152|M.tuberculosis_H37Rv         --------------------------------------------------
MMAR_4301|M.marinum_M               --------------------------------------------------
MUL_0993|M.ulcerans_Agy99           --------------------------------------------------
MAV_1290|M.avium_104                --------------------------------------------------
TH_3932|M.thermoresistible__bu      --------------------------------------------------
MAB_3582|M.abscessus_ATCC_1997      TTRWLTDGTAAKLEKQRREDARQRQVIARAELAGLDYHAHPASYSGWLTL
                                                                                      

Mflv_2135|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_4569|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_5174|M.smegmatis_MC2_155      --------------------------------------------------
Mb1183|M.bovis_AF2122/97            --------------------------------------------------
Rv1152|M.tuberculosis_H37Rv         --------------------------------------------------
MMAR_4301|M.marinum_M               --------------------------------------------------
MUL_0993|M.ulcerans_Agy99           --------------------------------------------------
MAV_1290|M.avium_104                --------------------------------------------------
TH_3932|M.thermoresistible__bu      --------------------------------------------------
MAB_3582|M.abscessus_ATCC_1997      PEHARSDVIAHELAEHGIMVTTADAFATTAHAPNALRLALATPELSELTA
                                                                                      

Mflv_2135|M.gilvum_PYR-GCK          ----------
Mvan_4569|M.vanbaalenii_PYR-1       ----------
MSMEG_5174|M.smegmatis_MC2_155      ----------
Mb1183|M.bovis_AF2122/97            ----------
Rv1152|M.tuberculosis_H37Rv         ----------
MMAR_4301|M.marinum_M               ----------
MUL_0993|M.ulcerans_Agy99           ----------
MAV_1290|M.avium_104                ----------
TH_3932|M.thermoresistible__bu      ----------
MAB_3582|M.abscessus_ATCC_1997      ALRHIRTATT