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M. thermoresistible (build 8) TH_3988 (-)

annotation: putative MFS permease
coordinates: 4240469 - 4241428
length: 320

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_3988--100% (320)putative MFS permease
M. thermoresistible (build 8)TH_3965-2e-0723.28% (189) PUTATIVE drug transporter
M. thermoresistible (build 8)TH_0476-2e-0623.94% (259) major facilitator superfamily protein MFS_1

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb0197-8e-3030.11% (269) integral membrane protein
M. gilvum PYR-GCKMflv_1840-2e-3031.97% (294) major facilitator transporter
M. tuberculosis H37RvRv0191-8e-3030.11% (269) integral membrane protein
M. leprae Br4923-----
M. abscessus ATCC 19977MAB_1429-2e-2833.22% (283) major facilitator superfamily permease
M. marinum MMMAR_0577-5e-3131.21% (282) integral membrane transport protein
M. avium 104MAV_4987-2e-2829.80% (302) sugar transporter family protein
M. smegmatis MC2 155MSMEG_0232-4e-3433.57% (280) sugar transporter family protein
M. ulcerans Agy99MUL_1084-5e-3031.16% (276) integral membrane protein
M. vanbaalenii PYR-1Mvan_4890-1e-3033.33% (303) major facilitator superfamily transporter

CLUSTAL 2.0.9 multiple sequence alignment


Mb0197|M.bovis_AF2122/97            -------MTAPTGTSATTTRPWTPRIATQLSVLACAAFIYVTAEILPVGA
Rv0191|M.tuberculosis_H37Rv         -------MTAPTGTSATTTRPWTPRIATQLSVLACAAFIYVTAEILPVGA
MUL_1084|M.ulcerans_Agy99           -------MTSEARTATTAARPWTPRVAAQLSVLAAAAFIYVTAEILPVGA
MAV_4987|M.avium_104                -------MTAET--ANAAARTWTPRIAAQLAILAAAAFTYVTAEILPVGA
MSMEG_0232|M.smegmatis_MC2_155      -------MTVTP----PTVSPWTVRVAAQLTVLAAAAFIYVTAEILPVGA
Mflv_1840|M.gilvum_PYR-GCK          ---MSAAVDQQSTPGASVAAPDPVVRRLAVLALALGGFGIGTTEFVAMGL
Mvan_4890|M.vanbaalenii_PYR-1       ---MTDTLHRPSGP-VSVAAPDPVVRRLAVVALALGGFGIGTTEFVAMGL
MAB_1429|M.abscessus_ATCC_1997      ---MTAVVDSRVQP---AAPVSPRVRRGAILALALGGFGIGTTEFVAMGL
MMAR_0577|M.marinum_M               ----------MPESVTAPPELGIRHATPGLLALTIATCLAITTEILPVGL
TH_3988|M.thermoresistible__bu      MSESKASQDASAPAADPVDATARRTPWIAILAAALGIFVMITIEELPIGV
                                                                 :   : .     * * :.:* 

Mb0197|M.bovis_AF2122/97            LSAIARNLRVSVVLVGTLLSWYALVAAVTTVPLVRWTAHWPRRRALVVSL
Rv0191|M.tuberculosis_H37Rv         LSAIARNLRVSVVLVGTLLSWYALVAAVTTVPLVRWTAHWPRRRALVVSL
MUL_1084|M.ulcerans_Agy99           LSAIARNLHISVVLVGTLLSWYALVAALTTVPLVRWTAHWPRRHALMVSL
MAV_4987|M.avium_104                LPAIARNLQVSLVLVGTLLSWYALVAALTTIPLVRWTAHLPRRRVLVASL
MSMEG_0232|M.smegmatis_MC2_155      LPVIAADLNVSEGLVGTLMAGYALIAALTTVALVRLTARWPRRRALLVTM
Mflv_1840|M.gilvum_PYR-GCK          LPDIARSFDVSEPVAGHVISAYALGVVVGAPLIAAITARMARRTLLLALM
Mvan_4890|M.vanbaalenii_PYR-1       LPDIATGMGVSEPTAGHVISAYALGVVVGAPVIAAVTARMARRKLLLALM
MAB_1429|M.abscessus_ATCC_1997      LPNIAHGLHVTEPQAGHVISAYALGVVVGAPVIAALTARASRRTLLVALM
MMAR_0577|M.marinum_M               LPAIGHTFGVRDAVTGLLVSLYAVLVALLAVPLTVVTARFPRKPLLLTTL
TH_3988|M.thermoresistible__bu      LTLIGDDLGLSSGVVGLTVTIPGVLAGAVAVLTPTLIGRLDRRLALVSAL
                                    *. *.  : :    .*  ::  .: .   :       .:  *:  *:  :

Mb0197|M.bovis_AF2122/97            VCLTVSQLVSALAPNFAVLAAGRVLCAVTHGLLWAVIAPIATRLVPPSHA
Rv0191|M.tuberculosis_H37Rv         VCLTVSQLVSALAPNFAVLAAGRVLCAVTHGLLWAVIAPIATRLVPPSHA
MUL_1084|M.ulcerans_Agy99           VCLTISQLISALAPNFAVLAAGRALCAITHGLLWSVIAPIATRLVPPSHA
MAV_4987|M.avium_104                TCLTASQLISALAPNFAVLAAGRVLCAITHGLLWSVIAPIATRLVPPSHA
MSMEG_0232|M.smegmatis_MC2_155      VCLTVSQVISAMAPNFAVLAGGRVLCALAHGLMWSVIAPIGVRLVPPSHA
Mflv_1840|M.gilvum_PYR-GCK          AVFTLGNLASMLASSYETLVGARFLAGLPHGAYFGVAALVAAHLMGPQHR
Mvan_4890|M.vanbaalenii_PYR-1       ALFTIGNLASMLAPTYETLIAARFLAGLPHGAYFGVAALVAAHLMGPQNR
MAB_1429|M.abscessus_ATCC_1997      VAFTIGNAATVFAPGYAALIASRFVAGLPHGAYFGVAALVAAHLAGPGER
MMAR_0577|M.marinum_M               LGYAVSNTLVAIAPTFAMVAAGRAVGGVTHALFFSLCIGYAPRLVGLADV
TH_3988|M.thermoresistible__bu      LLVFVSAATSAIAPNLPVLLASRLFAGMAIGVFWALLAVVVARVAHPDDL
                                         .     :*.    : ..* . .:. .  :.:      ::    . 

Mb0197|M.bovis_AF2122/97            GRATTSIYIGTSLALVVGSPLTAAMSLMWGWRLAAVCVTGAAAAVALAAR
Rv0191|M.tuberculosis_H37Rv         GRATTSIYIGTSLALVVGSPLTAAMSLMWGWRLAAVCVTGAAAAVALAAR
MUL_1084|M.ulcerans_Agy99           GRATTSIYIGTSLALVIGSPLTAALSLMWGWRLAAVCVTVAAAVVTVAAR
MAV_4987|M.avium_104                GRATMSIYVGTSLALVVGSPLTAALSLMWGWRLAVVCVTVAAAVVTVAAR
MSMEG_0232|M.smegmatis_MC2_155      GRATAAVYVGTGLALVVGNPLTAALSELWGWRQAVVAVAIAAAAVTLAAR
Mflv_1840|M.gilvum_PYR-GCK          AKAVAHVLTGLTVATVLGVPVASWLGQSLGWR-AAFGLVVAVGVLTLTAL
Mvan_4890|M.vanbaalenii_PYR-1       AKAVAHVLTGLTVATVLGVPIASWLGQSLGWR-AAFGLVVGVGLVTLTAL
MAB_1429|M.abscessus_ATCC_1997      AKAVGQTMLGLSVANVVGVPVATWLGNTVGWR-SAFAVVAVIGAITIAAL
MMAR_0577|M.marinum_M               GRALALVGGGVSAGIVVGVPLLTSVGTAVGWRGAFAVLAVLAAVLLLVVA
TH_3988|M.thermoresistible__bu      PKALTLAFGGVSVAVVLGVPFAAWIGAMVGWRWAFVLVGALGLMVAVALT
                                     :*      *   . *:* *. : :.   *** :   :      : :.  

Mb0197|M.bovis_AF2122/97            LALPEMVLRADQLEHVGRRARHHRNPRLVKVSVLTMIAVTGHFVSYTYIV
Rv0191|M.tuberculosis_H37Rv         LALPEMVLRADQLEHVGRRARHHRNPRLVKVSVLTMIAVTGHFVSYTYIV
MUL_1084|M.ulcerans_Agy99           LLLPEMVLSADQLQHVGPRSRHHRNRALIIVSLITMVGVTGHFVSYTYIV
MAV_4987|M.avium_104                LMLPEMVLTEHQLAHVGPRSRHHRNGRLITVSLLAMVAVTGHFVSYTFIV
MSMEG_0232|M.smegmatis_MC2_155      VLLPLMPAERARAGSAG-RPVHGRG--LLTLSLLTLIGVTGHFVAYTFIV
Mflv_1840|M.gilvum_PYR-GCK          ALWLPVQLRLMRSTSPLTELGALRRPQVWLALAVGMIGFGGMFAVYTYIA
Mvan_4890|M.vanbaalenii_PYR-1       WCWLPFQLKFMRATSPLTELGALRRPQVWLALLVGMIGFGGMFAVYTYIT
MAB_1429|M.abscessus_ATCC_1997      LRYLP-GLTDMRITNPLTELGALRRVQVWFTLLIGIVGFGGMFAFYTYIS
MMAR_0577|M.marinum_M               KLLPPVSSES----APPPAGTAKGRRRLAAVVSSNALTYTGQFTLYTFIS
TH_3988|M.thermoresistible__bu      VLLPPVPVAER--TTLGQLGAAWSIPAARTGVLVTLVMVTAHFTAYTYAS
                                                                        :   . *. **:  

Mb0197|M.bovis_AF2122/97            VIIRDVVGVRGPNLAWLLAAYGVAGLVSVPLVARPLDRWPKGAVIVGMTG
Rv0191|M.tuberculosis_H37Rv         VIIRDVVGVRGPNLAWLLAAYGVAGLVSVPLVARPLDRWPKGAVIVGMTG
MUL_1084|M.ulcerans_Agy99           VIIRQVVGVRGPSLAWLLAAYGVAGVVAVALVARPLDRRPKGTIIFCVAG
MAV_4987|M.avium_104                EIIRNVVGVRGPTLAWVLAAYGLAGLLSVPLVARPLDHRPKSAVILCMTG
MSMEG_0232|M.smegmatis_MC2_155      AIIRDVVGIDGPHLAWLLAGYGVAGLAAMAAMARPLDLWPKASVTAALVV
Mflv_1840|M.gilvum_PYR-GCK          TTMTDVAGMPRALVPVALMVFGLGMFFGNLVGGRLADRSVVRALYLSMGA
Mvan_4890|M.vanbaalenii_PYR-1       TTMTDVAGMPRGLVPLALMMFGLGMVLGNLVGGRLADGSVVRALYLSLGA
MAB_1429|M.abscessus_ATCC_1997      TTLTSVSGLPRALVPLALSLYGIGMVTGNVLGGWMADRSVVRAIAVGLVL
MMAR_0577|M.marinum_M               AVLLAAG-ARPAFIGPLLLMCGVCSLAGLWYVGATLDRNPRQTTVIIIVV
TH_3988|M.thermoresistible__bu      PVLQDRIHITESGVGPMLFVFGIAGFLGNFAAGPLLRRSMRATYVVLPIG
                                      :          :   *   *:  . .    .         :       

Mb0197|M.bovis_AF2122/97            LTAAFTLLTALAFGERHTAAT--ALLG-TGAIVLWGALATAVSPMLQSAA
Rv0191|M.tuberculosis_H37Rv         LTAAFTLLTALAFGERHTAAT--ALLG-TGAIVLWGALATAVSPMLQSAA
MUL_1084|M.ulcerans_Agy99           LTFAFVLLTALAFGGHLAPMT--ALVVGTGAIVLWGAAVTAVSPMLQSAA
MAV_4987|M.avium_104                LTAAFAVLTALAFGGPTGATT--ALIG-TAAIVLWGAMATAVSPMMQSAA
MSMEG_0232|M.smegmatis_MC2_155      LAASLVTLAVLSAQPRAGVTTGAVMVIGTVAIVLWGASSTALPPMLQTSA
Mflv_1840|M.gilvum_PYR-GCK          LCAMLTLFVAASHNPWTALLA----------LFGIGLTGSAVGPALQTRL
Mvan_4890|M.vanbaalenii_PYR-1       LCGALALFVVASHNPWTALLV----------LFLIGLTGSAVGPALQTRL
MAB_1429|M.abscessus_ATCC_1997      VAAMLLIFAAVSRNPWAALAL----------VFAVGVSGTSLVPALQTRL
MMAR_0577|M.marinum_M               VIGALLGLGASFPALLPVVLA----------AAVWNGAFGGIPSIYQAGA
TH_3988|M.thermoresistible__bu      VMVGVXXXGPNSRWRPDGTRM-----------------------------
                                    :   .                                             

Mb0197|M.bovis_AF2122/97            MRSGGDDPDGASGLYVTAFQIGIMAGALLGGLLYERS-LAMMLTASAGLM
Rv0191|M.tuberculosis_H37Rv         MRSGGDDPDGASGLYVTAFQIGIMAGALLGGLLYERS-LAMMLTASAGLM
MUL_1084|M.ulcerans_Agy99           MRSGADDPDGASGLYVTAFQVGIMAGSLIGGLLYERS-VAMMLTASAGLM
MAV_4987|M.avium_104                MRNGADDPDGASGLYVTAFQVGIMAGSLLGGLLYERS-VILMLSASGVLM
MSMEG_0232|M.smegmatis_MC2_155      MRTSPEDPDGASGRYVAAFQVGIMTGALVGAGVYEAVGLTAMIGTAAVLI
Mflv_1840|M.gilvum_PYR-GCK          MDVAHDAQTLAAALNHSALNIGNATGAWVGGLVIAAGYGYTAPAGAGAVL
Mvan_4890|M.vanbaalenii_PYR-1       MDVAHDAQTLAAALNHSALNIGNATGAWVGGLVIAAGLGYTAPAAAGAVL
MAB_1429|M.abscessus_ATCC_1997      MDVADDAQTLAAALNHSALNIANAGGAWLGGLVITAGYGYRAPSLVGAAL
MMAR_0577|M.marinum_M               VRAQAATPEMAGAWVNATANLGIAAGAAIGAGLLPTIGLAGLPWVAAALI
TH_3988|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mb0197|M.bovis_AF2122/97            GVALFGMTVSQHLFENPTLSPGDG----
Rv0191|M.tuberculosis_H37Rv         GVALFGMTVSQHLFENPTLSPGDG----
MUL_1084|M.ulcerans_Agy99           GVALVGMTSARRVFEAPVAVAGATSHNQ
MAV_4987|M.avium_104                AVALVGIAANRRMLDVAPTSSRDS----
MSMEG_0232|M.smegmatis_MC2_155      TAAMCGALAVPDVFNRSRDLSTR-----
Mflv_1840|M.gilvum_PYR-GCK          ALAGLVVLTVSVVLQKR-----------
Mvan_4890|M.vanbaalenii_PYR-1       ALAGLAVLTVSVLLQKRG----------
MAB_1429|M.abscessus_ATCC_1997      AIAGLVVLGLSVLYARSRAVALPSRAG-
MMAR_0577|M.marinum_M               AISLAVTLATGRGPTH------------
TH_3988|M.thermoresistible__bu      ----------------------------