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VDLGLRDATAVVVGGGRGMGLAAAHCFADDGARVALIGRSPEVLDGAAAQLRERGSPDAVGVVADTTDDA AVRRAFAELGERWNGELNILVNAVGPTVRGTFDELTDADWRQAVDEGAMGMVHCVRAALPLLRAAEWARI VNFSAHSTQRQSVILPAYTAAKAMVTSISKNLSLLLARDEILVNVVSPGSIASEALLGWADSVGVDGSDP YALMAAIDEHFGHPAHLPRAGLPTEIGPVVAFLASRRNSYMTGANINVDGGSDFT
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_1991 | - | - | 100% (265) | short-chain dehydrogenase/reductase SDR |
| M. vanbaalenii PYR-1 | Mvan_4157 | - | 1e-26 | 33.33% (252) | short-chain dehydrogenase/reductase SDR |
| M. vanbaalenii PYR-1 | Mvan_4185 | - | 4e-26 | 33.60% (253) | short-chain dehydrogenase/reductase SDR |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2788c | fabG | 6e-22 | 31.54% (260) | 3-ketoacyl-(acyl-carrier-protein) reductase |
| M. gilvum PYR-GCK | Mflv_4353 | - | 1e-138 | 92.45% (265) | short-chain dehydrogenase/reductase SDR |
| M. tuberculosis H37Rv | Rv2766c | fabG | 7e-22 | 31.54% (260) | 3-ketoacyl-(acyl-carrier-protein) reductase |
| M. leprae Br4923 | MLBr_01807 | fabG1 | 3e-15 | 28.97% (252) | 3-oxoacyl- |
| M. abscessus ATCC 19977 | MAB_0833 | - | 1e-21 | 31.13% (257) | Short-chain dehydrogenase/reductase |
| M. marinum M | MMAR_1568 | - | 1e-68 | 51.12% (268) | short-chain type dehydrogenase/reductase |
| M. avium 104 | MAV_1587 | - | 1e-116 | 76.60% (265) | oxidoreductase, short chain dehydrogenase/reductase family |
| M. smegmatis MC2 155 | MSMEG_2228 | - | 1e-118 | 77.74% (265) | oxidoreductase, short chain dehydrogenase/reductase family |
| M. thermoresistible (build 8) | TH_4608 | - | 1e-124 | 81.06% (264) | PUTATIVE short-chain dehydrogenase/reductase SDR |
| M. ulcerans Agy99 | MUL_0315 | fabG2 | 8e-26 | 33.85% (260) | 3-oxoacyl- |
CLUSTAL 2.0.9 multiple sequence alignment
Mvan_1991|M.vanbaalenii_PYR-1 --------------MDLGLRDATAVVVGGGRGMGLAAAHCFADDGARVAL
Mflv_4353|M.gilvum_PYR-GCK --------------MDLGLRDATVVVVGGGRGMGLAAAHCFADDGARVAL
TH_4608|M.thermoresistible__bu --------------MDLGFTDAAAVVVGGGRGMGLAAAQCLADDGARVAV
MAV_1587|M.avium_104 --------------MDLGLANAAAVVVGGSRGMGLATARCLADEGARVAV
MSMEG_2228|M.smegmatis_MC2_155 --------------MDLGFGGAAAAVVGGGRGMGFATAQCLADDGARVAV
MMAR_1568|M.marinum_M --------------MDLGFSGSKAVVTGGSKGMGLAIAETLAAEGASVAV
Mb2788c|M.bovis_AF2122/97 -------------MTSLDLTGRTAIITGASRGIGLAIAQQLAAAGAHVVL
Rv2766c|M.tuberculosis_H37Rv -------------MTSLDLTGRTAIITGASRGIGLAIAQQLAAAGAHVVL
MAB_0833|M.abscessus_ATCC_1997 -------MNRETFSRLFDLTGRTAIVTGGTRGIGRALAEGYACAGANVVV
MLBr_01807|M.leprae_Br4923 MTDAAAKVSAAPGRGKPAFVSRSILVTGGNRGIGLAVARRLVADGHRVAV
MUL_0315|M.ulcerans_Agy99 ---------MRPD-SSPSWCTITSVVTGGASGIGLAIARRLSADGTDVAT
:.*. *:* * *. * *.
Mvan_1991|M.vanbaalenii_PYR-1 IGRSPEVLDGAAAQLRERGSPDAVGVVADTTDDAAVRRAFAELGERWNGE
Mflv_4353|M.gilvum_PYR-GCK VGRTRDVLDEAAAQLRGRGSPDAVGVVADCADEAAVQRAFGELAERWNGE
TH_4608|M.thermoresistible__bu IGRTRSMLDEAAADLARRGSPDALGIVADIRDEQQVERVFAELGERWQGE
MAV_1587|M.avium_104 IGRSRDALDSAVTDLTRRGSPDALGLVADIGDDAAVGQAFGELARRWDGE
MSMEG_2228|M.smegmatis_MC2_155 IGRSKDVLETAASDLARRGSPDAIAIVADTGDAEQVERAFAEIGERWDGE
MMAR_1568|M.marinum_M IARGKRALDSAVERLSQAGAPDAVAISADMADAASITSAFAAVSERWG-Q
Mb2788c|M.bovis_AF2122/97 TARRQEAADEAAAQV----GDRALGVGAHAVDEDAARRCVDLTLERFGSV
Rv2766c|M.tuberculosis_H37Rv TARRQEAADEAAAQV----GDRALGVGAHAVDEDAARRCVDLTLERFGSV
MAB_0833|M.abscessus_ATCC_1997 ASRKPEACTEAVERLR-SLGARALGVPTHTGDIHSLEELVRATAEEFGGI
MLBr_01807|M.leprae_Br4923 THRAS------------VVPDWFFGVECDVTDNDAIGAAFKAVEEHQGPV
MUL_0315|M.ulcerans_Agy99 LDLK--------------TPDGGLAFSADVTNRSQVDAALAAIRQRLGPV
... . : . ..
Mvan_1991|M.vanbaalenii_PYR-1 LNILVNAVGPTVRGTFDELTDADWRQAVDEGAMGMVHCVRAALPLLRAAE
Mflv_4353|M.gilvum_PYR-GCK LNVLVNAVGPTVRGTFDELSDADWRQAVDEGAMGMVRCVRAALPLLRAAE
TH_4608|M.thermoresistible__bu LNVLINTVGPAVMGTVEELSDEQWRSAVDDGVLGMVHCVRSALPLLRQAE
MAV_1587|M.avium_104 LNALVITVGPGAAGTFEDLTDEQWRQAVEDGVLGMVRCVRAALPLLRKAQ
MSMEG_2228|M.smegmatis_MC2_155 LNVLINTVGPGAAGDFEELTDGQWQEAFDAGVMGMVRCVRAALPLLRKAE
MMAR_1568|M.marinum_M LNCLVHTIGPGD-GYFEELDDAAWDAAFTLGTMSGVRAIRAALPLLRAAD
Mb2788c|M.bovis_AF2122/97 DILINNAGTNPAYGPLLEQDHARFAKIFDVNLWAPLMWTSLVVTAWMGEH
Rv2766c|M.tuberculosis_H37Rv DILINNAGTNPAYGPLLEQDHARFAKIFDVNLWAPLMWTSLVVTAWMGEH
MAB_0833|M.abscessus_ATCC_1997 DIVVNNA-ANALTEPVGAFTVDGWDKSFGVNLRGPVFLVQAALPHLVASP
MLBr_01807|M.leprae_Br4923 EVLVANAGITSDML-IMRMSEEQFQKVIDVNLTGVFRVAKLASRNMIKQR
MUL_0315|M.ulcerans_Agy99 TILVNAAGLDGFKR-FSNITFEDWQRVIDVNLNGVFHTIQAVLPDMVAAG
: : . : . . . . .
Mvan_1991|M.vanbaalenii_PYR-1 WARIVNFSAHSTQRQSVILPAYTAAKAMVTSISKNLSLLLARDEILVNVV
Mflv_4353|M.gilvum_PYR-GCK WARIVNFSAHSTQRQSVILPAYTAAKAMVTSISKNLSLLLARDEILVNVV
TH_4608|M.thermoresistible__bu WARIVNLSAHSTQRQSVILPAYTAAKAMVTSISKNLSLLLAKDEILVNVV
MAV_1587|M.avium_104 WARIVNFSAHSTQRQSVLLPAYTAAKSMLTSVSKNLSLLLAKDEILVNVI
MSMEG_2228|M.smegmatis_MC2_155 WARIVNFSAHSTQRQSTRLPAYTAAKAAVNSVSKNLSLLLAKDEIMVNVV
MMAR_1568|M.marinum_M WARVVTLSAHSIQRQNPRLVAYTASKAALSSVTKNLSKSLAKEGILVNCV
Mb2788c|M.bovis_AF2122/97 GGAVVNTASIGGMHQSPAMGMYNATKAALIHVTKQLALELSPR-IRVNAI
Rv2766c|M.tuberculosis_H37Rv GGAVVNTASIGGMHQSPAMGMYNATKAALIHVTKQLALELSPR-IRVNAI
MAB_0833|M.abscessus_ATCC_1997 HAAVLNVVSVGAFMFGQGVSMYSAAKAALVSYTRSAAAELASRGVRVNAL
MLBr_01807|M.leprae_Br4923 FGRYIFMGSVVGLSGVPGQANYAASKSGLIGMARSLARELGSRSITANVV
MUL_0315|M.ulcerans_Agy99 WGRIVNISSSSTHSGTPYMTHYVAAKSAVNGLTKALALEYGPSGITVNAV
. : : * *:*: : :: : . : .* :
Mvan_1991|M.vanbaalenii_PYR-1 SPGSIAS----EALLGWADSVGVDGSDPYALMAAIDEHFGHPAHLPRAGL
Mflv_4353|M.gilvum_PYR-GCK SPGSIAS----EALVGWADSVGVDGSDPYALMAAIDEHFGHPAHLPRAGL
TH_4608|M.thermoresistible__bu SPGSIAS----EALVGWADSIGVDGTDPYALMSAIDEHFGHPAHLPRAGL
MAV_1587|M.avium_104 SPGSIAS----ESLVGWANSVGVDGRDPYALMEAIGKHFGHPAHMPRAGL
MSMEG_2228|M.smegmatis_MC2_155 SPGSISS----EALVGWAESVGVDGSDPYQLMAAIDEHFGHPAHLPRAGL
MMAR_1568|M.marinum_M CPGTIVTASFTEQLKDLLAADGLDATNPYDVMAWIDKYFHQPCDLGRAGL
Mb2788c|M.bovis_AF2122/97 CPGVVRT--------------RLAEALWKD----HEDPLAATIALGRIGE
Rv2766c|M.tuberculosis_H37Rv CPGVVRT--------------RLAEALWKD----HEDPLAATIALGRIGE
MAB_0833|M.abscessus_ATCC_1997 APGAIDT--------------DMVRKTPPA----EVERMANTNHLKRLGL
MLBr_01807|M.leprae_Br4923 APGFIDT--------------EMTRAMDSK----YQEAALQAIPLGRIGA
MUL_0315|M.ulcerans_Agy99 PPGFIDT--------------PMLRNAAAQGHLGDIEQNIARTPVRRIGK
** : : : . : * *
Mvan_1991|M.vanbaalenii_PYR-1 PTEIGPVVAFLASRRNSYMTGANINVDGGSDFT-------------
Mflv_4353|M.gilvum_PYR-GCK PTEIGSVVAFLASRRNSYMTGADINVDGGSDFT-------------
TH_4608|M.thermoresistible__bu PEEIGPVIAFLASRRNSYMTGANVNVDGGSDFV-------------
MAV_1587|M.avium_104 PEEIGPVAAFLASRRNSYMTGANINVDGGSDFT-------------
MSMEG_2228|M.smegmatis_MC2_155 PSEIGPVAAFLASRRNSYMTGANINVDGGSDFT-------------
MMAR_1568|M.marinum_M PEEVASITAYLVSRRNGYVTGATVNADGGSDFI-------------
Mb2788c|M.bovis_AF2122/97 PADIASAVAFLVSDAASWITGETMIIDGGLLLGNALGFRAAPSTEH
Rv2766c|M.tuberculosis_H37Rv PADIASAVAFLVSDAASWITGETMIIDGGLLLGNALGFRAAPSTEH
MAB_0833|M.abscessus_ATCC_1997 PDEMVGTALLLTSDAGSYITGQTIIADGGLVAR-------------
MLBr_01807|M.leprae_Br4923 VEEIAGAVSFLASEDAGYISGAVIPVDGGLGMGH------------
MUL_0315|M.ulcerans_Agy99 PEDIAAACAFLVSEEAGYITGQILGVNGGRNT--------------
:: *.* .:::* : :**