For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
aa seq not available
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. thermoresistible (build 8) | TH_3419 | - | - | 100% (488) | putative aldehyde dehydrogenase |
M. thermoresistible (build 8) | TH_4531 | - | e-127 | 50.63% (478) | PUTATIVE putative betaine aldehyde dehydrogenase |
M. thermoresistible (build 8) | TH_2957 | - | e-123 | 49.48% (477) | PUTATIVE aldehyde dehydrogenase |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb2883c | aldC | 4e-76 | 40.00% (455) | aldehyde dehydrogenase |
M. gilvum PYR-GCK | Mflv_1907 | - | 1e-117 | 46.95% (475) | aldehyde dehydrogenase |
M. tuberculosis H37Rv | Rv0223c | - | 2e-87 | 40.21% (475) | aldehyde dehydrogenase |
M. leprae Br4923 | MLBr_02573 | gabD1 | 3e-67 | 37.05% (440) | succinic semialdehyde dehydrogenase |
M. abscessus ATCC 19977 | MAB_4484 | - | 2e-88 | 41.89% (475) | aldehyde dehydrogenase |
M. marinum M | MMAR_0472 | - | 1e-84 | 39.38% (480) | aldehyde dehydrogenase |
M. avium 104 | MAV_3553 | - | 1e-116 | 46.62% (474) | aldehyde dehydrogenase |
M. smegmatis MC2 155 | MSMEG_5815 | - | 1e-116 | 48.00% (475) | betaine aldehyde dehydrogenase |
M. ulcerans Agy99 | MUL_1122 | - | 3e-82 | 38.54% (480) | aldehyde dehydrogenase |
M. vanbaalenii PYR-1 | Mvan_0240 | - | 6e-90 | 40.42% (475) | betaine-aldehyde dehydrogenase |
CLUSTAL 2.0.9 multiple sequence alignment Mflv_1907|M.gilvum_PYR-GCK ---MVADPVTPIGLLIGTDRLTRTSLAPHPHIYPATGAPNATVALAGADE MSMEG_5815|M.smegmatis_MC2_155 -MTSVVLPGDPIGSLIGDRRVTASSGGLHAHVYPATGLPNATVALAGAAE MAV_3553|M.avium_104 MTATASSPPRTGALLIGTERITAASGGSHQHRYPGTGVPNATIPLAGHSE TH_3419|M.thermoresistible__bu VQRTLPDKLPAPRLVIGGGDVISTSGGVYEHHYAATGGVQAEVPLAGPAE Mb2883c|M.bovis_AF2122/97 ---------------MSTTQLIN----------PATEEVLASVDHTDANA MMAR_0472|M.marinum_M ----MGEKTEYDKLFIGGKWTEPSTSEVIEVHCPATGEYVGKVPLAAAAD MUL_1122|M.ulcerans_Agy99 ----MGEKTEYDKLFIGGRWTEPSTSEVIEVHCPATGEYVGKVPLAAAAD Rv0223c|M.tuberculosis_H37Rv ---MSDSATEYDKLFIGGKWTKPSTSDVIEVRCPATGEYVGKVPMAAAAD MAB_4484|M.abscessus_ATCC_1997 -------MTNYDKLFIGGVWTEPATDQVIEVISPATGQKVGQCPLASPAD Mvan_0240|M.vanbaalenii_PYR-1 MTQSTTFRTEWDKLFIGGKWVEPATSDVIEVHSPATGELVGKVPLASAAD MLBr_02573|M.leprae_Br4923 --------------------------MSIATINPATGETVKTFTPTTQDE ..* : Mflv_1907|M.gilvum_PYR-GCK VGMAVSAAREAQR--EWITLGVDQRRDKLIDLADVVREHLGELAELNTLD MSMEG_5815|M.smegmatis_MC2_155 VDAAVSAAWEAHR--EWVAHPADRRRDMLVGLADVVHEHLDELAGLNVHD MAV_3553|M.avium_104 VDRAVHSAREAQR--EWISYPVDRRRDLLFGLADLLRDHFAELTELNVHD TH_3419|M.thermoresistible__bu VDAAVAAARAAFP--AWRDLDLNRRRDILQELARRLVADGERLGAIATLE Mb2883c|M.bovis_AF2122/97 VDDAVQRARAAQR--RWARLAPAQRAAGLRAFAAAVQAHLDELAALEVAN MMAR_0472|M.marinum_M VDAAVAAARAAFDNGPWPSTPPKERATVIANALKLLEERKDHFAKLLADE MUL_1122|M.ulcerans_Agy99 VDAAVAAARAAFDNGPWPSTPPKERATVIANALKLLEERKDHFAKLFADE Rv0223c|M.tuberculosis_H37Rv VDAAVAAARAAFDNGPWPSTPPHERAAVIAAAVKMLAERKDLFTKLLAAE MAB_4484|M.abscessus_ATCC_1997 VDAAVSAARRAFDNGPWPRLTPHERQAVLQKAVSLLESRKDEICKAIADE Mvan_0240|M.vanbaalenii_PYR-1 VDAACAAAREAFDNGPWPHMSPAERGEILGRAVKIMEERADELKFLLAAE MLBr_02573|M.leprae_Br4923 VEDAIARAYARFDN--YRHTTFTQRAKWANATADLLEAEANQSAALMTLE * * * : .* : . : Mflv_1907|M.gilvum_PYR-GCK YGVP-ISYAGNAVMLDQ-FLRHFAGYVDKPHGSSTPVSGSSDVNLIER-- MSMEG_5815|M.smegmatis_MC2_155 YAVP-ISNAGTALLLER-FLRHFAGYADKPHGTSSPVSGSFDVNIIER-- MAV_3553|M.avium_104 YGVP-ISVAGNSVLTER-FVRYYAGYPDKLTGASTPVSGAFDVNIVER-- TH_3419|M.thermoresistible__bu VGTPNLLASSSSAMAAD-WFTYYAGWIGRSAGEVVPVPAGGALDYVLD-- Mb2883c|M.bovis_AF2122/97 SGHPIVSAEWEAGHVRD-VLAFYAASPERLSGRQIPVAGG--VDVTFN-- MMAR_0472|M.marinum_M TGQPPMTVETMHWMGSIGALNFFAGPAVDQVRWKEIRNGSYGQTIVHR-- MUL_1122|M.ulcerans_Agy99 TGQPPMTVETMHWMGSIGALNFFAGPAVDQVRWKEIRNGSYGQTIVHR-- Rv0223c|M.tuberculosis_H37Rv TGQPPTIIETMHWMGSMGAMNYFAG-AADKVTWTETRTGSYGQSIVSR-- MAB_4484|M.abscessus_ATCC_1997 TGAPPMVIETLQWMGGFGAIQYYAN-AADAVKWKELRNGAYGQTLVTR-- Mvan_0240|M.vanbaalenii_PYR-1 TGQPPTIVDMMQYGAAMSSFQFYAG-AADKFTWQDIRDGVYGQTLVVR-- MLBr_02573|M.leprae_Br4923 MGKTLQSAKDEAMKCAK-GFRYYAEKAETLLADEPAEAAAVGASKALARY . . . .:* . Mflv_1907|M.gilvum_PYR-GCK EPFGAVGVIAPWNGSLVVAASCVAPALAAGNAVVFKPSELAPLAALRFGE MSMEG_5815|M.smegmatis_MC2_155 EPYGVVGVIAPWNGALAVAASCVAPALAAGNAVVFKPSELAPLAALRFGE MAV_3553|M.avium_104 EPYGVVAVIAPWNGPLVVAGAAVAPALAAGNAVIFKPSELASLAPLRFGE TH_3419|M.thermoresistible__bu EPLGVIAAIIPWNGPLISIGMKVAPALAAGNCVVLKPPENAPFSALRFAE Mb2883c|M.bovis_AF2122/97 EPMGVVGVITPWNFPMVIASWAIAPALAAGNAVLVKPAELTPLTTMRLGE MMAR_0472|M.marinum_M EPIGVVGAIVAWNVPLFLAINKLGPALLAGCTVVLKPAAETPLTANALAE MUL_1122|M.ulcerans_Agy99 EPIGVVGAIVAWNVPLFLAINKLGPAPLAGCTVVLKPAAETPLTANALAE Rv0223c|M.tuberculosis_H37Rv EPVGVVGAIVAWNVPLFLAVNKIAPALLAGCTIVLKPAAETPLTANALAE MAB_4484|M.abscessus_ATCC_1997 EPAGVVAAIAAWNVPLFLALNKIGPAFLAGCAVVLKPAAETPLSSFILAE Mvan_0240|M.vanbaalenii_PYR-1 EPVGVVGAVTAWNVPFFLAANKLGPALLAGCTVVLKPAAETPLSVFAMAE MLBr_02573|M.leprae_Br4923 QPLGVVLAVMPWNFPLWQTVRFAAPALMAGNVGLLKHASNVPQCALYLAD :* *.: .: .** .: .** ** :.* . .. :.: Mflv_1907|M.gilvum_PYR-GCK LCLEAGLPPGLVNILPA-AAEGGDALVRHAGIAKIHFTGGGHTARAILRA MSMEG_5815|M.smegmatis_MC2_155 LCLVAGLPPGLVNILPA-ASDGGDALVRHPGIRKIHFTGGGTTARAVLRA MAV_3553|M.avium_104 LCLEAGLPPGLVNVLPA-GPEGGEALVRHPGVGKVHFTGGHATAQQVLRA TH_3419|M.thermoresistible__bu LAAEAGLPPGVLNVIPG-GAEAGSALCSHPGVDKITFTGGGETARKVFAA Mb2883c|M.bovis_AF2122/97 LAVEAGLDEDLLQVLPGKGTVVGERFVTHPDIRKIVFTGSTEVGKRVMAG MMAR_0472|M.marinum_M VFAEAGLPEGVLSVVPG-GVETGQALTSNPGVDLFTFTGSSAVGKEIGRR MUL_1122|M.ulcerans_Agy99 VFAEAGLPEGVLSVVPG-GVETGQALTSNPGVDLFTFTGSSAVGKEIGRR Rv0223c|M.tuberculosis_H37Rv VFAEVGLPEGVLSVVPG-GIETGQALTSNPDIDMFTFTGSSAVGREVGRR MAB_4484|M.abscessus_ATCC_1997 VFAEAGVPEGVLSVVPG-GAETGRALTNNPDVDVFSFTGSTAVGKEIAEI Mvan_0240|M.vanbaalenii_PYR-1 MFVEAGLPEGVLSIVPG-GPETGQALTANPNLDKYTFTGSSGVGKEIAKI MLBr_02573|M.leprae_Br4923 VIARGGFPEDCFQTLLI-SANGVEAILRDPRVAAATLTGSEPAGQAVGAI : *. . .. : . : .. : :**. ..: : Mflv_1907|M.gilvum_PYR-GCK AADNLTPVVTELGGKSANIIFDDADLDIAAVRSAHQGPLMQSGQSCACAS MSMEG_5815|M.smegmatis_MC2_155 ATDNLTPVVTELGGKSANIIFPDADLGRAAALAAHQGPLMQSGQSCACAS MAV_3553|M.avium_104 ASDNVTPVTAELGGKSAYLVFADADLDTAAVIAAHQGPLTQAGQSCACAS TH_3419|M.thermoresistible__bu AAQALTPVVLELGGKSANIVFPDADLDAAATMAVSAGLMMLSGQGCILPT Mb2883c|M.bovis_AF2122/97 AAAQVKRVTLELGGKSANIVFHDCDLERAATTAP-AGVFDNAGQDCCARS MMAR_0472|M.marinum_M AAEMLKPCTLELGGKSAAILLEDVDLSTAVPMMVFSGIMN-TGQACVGQT MUL_1122|M.ulcerans_Agy99 AAEMLKPCTLELGGKSAAILLEDVDLSTAVPMMVFSGIMN-TGQACVGQT Rv0223c|M.tuberculosis_H37Rv AAEMLKPCTLELGGKSAAIILEDVDLAAAIPMMVFSGVMN-AGQGCVNQT MAB_4484|M.abscessus_ATCC_1997 AAKNLKKVTLELGGKSAAIVLEDADLAAALPMLVFSGLMN-AGQGCVNQT Mvan_0240|M.vanbaalenii_PYR-1 AADKLKPCTLELGGKSAAIILEDADLDSTLPMLVFSGLMN-SGQACVGQT MLBr_02573|M.leprae_Br4923 AGNEIKPTVLELGGSDPFIVMPSADLDAAVATAVTGRVQN-NGQSCIAAK * :. . ****... ::: . ** : ** * . Mflv_1907|M.gilvum_PYR-GCK RILVHEAVYEAFTERFIDVVESARIGDPLDPATVFGPVISAAALDRIVGV MSMEG_5815|M.smegmatis_MC2_155 RILVHESVYDAFTEQFLAVIGAARVGDPFDPEVNFGPVISAGSLDRLLNV MAV_3553|M.avium_104 RILVEASVYVSFVEKLVAQVQAATIGDPLRPDVMLGPVITEAAADRILGV TH_3419|M.thermoresistible__bu RLLVHDDVYDEMVTRVVAGADALTVGDPWQPTTMMGPLATAAQLERVTRA Mb2883c|M.bovis_AF2122/97 RILVQRSVYDRFMELLEPAVHSIVVGDPGSRATEMGPLVSRAHRDKVAGY MMAR_0472|M.marinum_M RILAPRSRYEEIVEAVSAFVQALPVGPPSDPAAQIGSLISEKQRARVEGY MUL_1122|M.ulcerans_Agy99 RILAPRSRYEEIVEAVSAFVQTLPVGPPSDPAAQIGSLISEKQRARVEGY Rv0223c|M.tuberculosis_H37Rv RILAPRSRYDEIVAAVTNFVTALPVGPPSDPAAQIGPLISEKQRTRVEGY MAB_4484|M.abscessus_ATCC_1997 RVLAPRSRYDEVVDGIVGMVSLMGVGLPDDPATQVGPLITEKQRTRVEGY Mvan_0240|M.vanbaalenii_PYR-1 RILAPRSRYDEVVEKLAAAAAGMAPGLPDNPAAMIGPLISEKQRDRVEGY MLBr_02573|M.leprae_Br4923 RFIAHADIYDEFVEKFVARMETLRVGDPTDPDTDVGPLATESGRAQVEQQ *.:. * . . * * . .*.: : :: Mflv_1907|M.gilvum_PYR-GCK VGEAVDSGSGDLLAGGRRLTEDSLAAGYYLEPTVLGNVDNTSPLAQTETF MSMEG_5815|M.smegmatis_MC2_155 VHRAVEERAGELLVGGERLVDGALAGGFYMQPTVFGGVDNRSRLAQVETF MAV_3553|M.avium_104 IERAVAEKAGDLVTGGRRLG-GELASGYFIEPTIFSNVDNRSSLAQTETF TH_3419|M.thermoresistible__bu VDSALSDKAGKLLAGGRRPD--GLDAGYFYRPTVFGDVDPASDLAQTEIF Mb2883c|M.bovis_AF2122/97 VPDDAPVAFRGTAPAG---------RGFWFPPTVLTPK-RGDRTVTDEIF MMAR_0472|M.marinum_M IAKGIEEGAR-LVSGGGRPE--GLDNGFFVQPTVFADVDNKMTIAQEEIF MUL_1122|M.ulcerans_Agy99 IAKGIEEGAR-LVSGGGRPE--SLDNGFFVQPTVFADVDNKMTIAQEEIF Rv0223c|M.tuberculosis_H37Rv IAKGIEEGAR-LVCGGGRPE--GLDNGFFIQPTVFADVDNKMTIAQEEIF MAB_4484|M.abscessus_ATCC_1997 IAKGIAEGAR-LAYGGKRPE--GLDGGYFVQPTIFADVDNSMTIAQEEIF Mvan_0240|M.vanbaalenii_PYR-1 IKKGIEEGAR-VVTGGGRPE--GLDSGWYVQPTVFADVDNSMTIAQEEIF MLBr_02573|M.leprae_Br4923 VDAAAAAGAV-IRCGGKRPD----RPGWFYPPTVITDITKDMALYTDEVF : .* *:: **:: * * Mflv_1907|M.gilvum_PYR-GCK GPVVSLIPFADDDGAVRIANDTPYGLNAFVHTRDLTRAHTVARRLQSGSV MSMEG_5815|M.smegmatis_MC2_155 GPVVSLIRFVDDDEAVRLANDTPYGLNAFVHTADLTRAHTVSRQLEAGSV MAV_3553|M.avium_104 GPVASVMPFADEAQAVSLANDSRYGLNAFVATANLERAHRVARRLQAGSV TH_3419|M.thermoresistible__bu GPVLAILRFRSEEEAVELANNTQYGLAAYIHTRDLRRAHVMAAALDAGGV Mb2883c|M.bovis_AF2122/97 GPVVVVLTFDDEADAISLANDTAYGLSGSIWTDDLSRALRVARAVESGNL MMAR_0472|M.marinum_M GPVLVVIPYDTEEDAIKIANDSVYGLAGSVWTSNVPKGIEISEKIRTGTY MUL_1122|M.ulcerans_Agy99 GPVLVVIPYDTKEDAIKIANDSVYGLAGSVWTSNVPKGIEISEKIRTGTY Rv0223c|M.tuberculosis_H37Rv GPVLAIIPYDTEEDAIAIANDSVYGLAGSVWTTDVPKGIKISQQIRTGTY MAB_4484|M.abscessus_ATCC_1997 GPVLSIIAYDSVDEAVKIANDSNYGLAGSVWTTDVQKGLEVAAQIRTGTY Mvan_0240|M.vanbaalenii_PYR-1 GPVLAVIPYEDEDDAVRIANDSVYGLAGSVYTTDNDRALKIARRIRTGTY MLBr_02573|M.leprae_Br4923 GPVASVYCATNIDDAIEIANATPFGLGSNAWTQNESEQRHFIDNIVAGQV *** : *: :** : :** . * : . . : :* Mflv_1907|M.gilvum_PYR-GCK WINQGSRISPQGPYGGYKQSGSGRTGGLEGLREFQQVKNIRIGIG----- MSMEG_5815|M.smegmatis_MC2_155 WVNQFSQISPQGPYGGYKQSGSGRTGGLDGLHEFQQIKNIRIGMG----- MAV_3553|M.avium_104 WVNRHSDIEPQGPYGGYKQSGFGRTGGVEGLHEFLQVKNIRIGMS----- TH_3419|M.thermoresistible__bu AVNGFPIVPSAAPFGGVKQSGFGREGGIWGLREFQRTKNVYIGLQ----- Mb2883c|M.bovis_AF2122/97 SVNSHSSVRFNTPFGGFKQSGVGRELGPDAPLQFTETKNVFIAVGEEM-- MMAR_0472|M.marinum_M AIN-WYAFDPCCPFGGYKNSGIGRENGPEGVEHFTQQKSVLMPMGYTLES MUL_1122|M.ulcerans_Agy99 AIN-WYAFDPCCPFGGYKNSGIGRENGPEGVEHFTQQKSVLMPMGYTLES Rv0223c|M.tuberculosis_H37Rv GIN-WYAFDPGSPFGGYKNSGIGRENGPEGVEHFTQQKSVLLPMGYTVA- MAB_4484|M.abscessus_ATCC_1997 GIN-WYAFDPSCPFGGYKQSGIGRENGPEGIEEYCELKSVLLPMGYTLES Mvan_0240|M.vanbaalenii_PYR-1 AVN-MYAFDPCAPFGGFKNSGIGRENGWEGIEAYCEPKSILLPFGYTPAT MLBr_02573|M.leprae_Br4923 FINGMTVSYPELPFGGIKRSGYGRELSTHGIREFCNIKTVWIA------- :* *:** *.** ** . . : . *.: : Mflv_1907|M.gilvum_PYR-GCK - MSMEG_5815|M.smegmatis_MC2_155 - MAV_3553|M.avium_104 - TH_3419|M.thermoresistible__bu - Mb2883c|M.bovis_AF2122/97 - MMAR_0472|M.marinum_M - MUL_1122|M.ulcerans_Agy99 - Rv0223c|M.tuberculosis_H37Rv - MAB_4484|M.abscessus_ATCC_1997 I Mvan_0240|M.vanbaalenii_PYR-1 - MLBr_02573|M.leprae_Br4923 -