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M. thermoresistible (build 8) TH_3419 (-)

annotation: putative aldehyde dehydrogenase
coordinates: 3007352 - 3008815
length: 488

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_3419--100% (488)putative aldehyde dehydrogenase
M. thermoresistible (build 8)TH_4531-e-12750.63% (478) PUTATIVE putative betaine aldehyde dehydrogenase
M. thermoresistible (build 8)TH_2957-e-12349.48% (477) PUTATIVE aldehyde dehydrogenase

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb2883caldC4e-7640.00% (455) aldehyde dehydrogenase
M. gilvum PYR-GCKMflv_1907-1e-11746.95% (475) aldehyde dehydrogenase
M. tuberculosis H37RvRv0223c-2e-8740.21% (475) aldehyde dehydrogenase
M. leprae Br4923MLBr_02573gabD13e-6737.05% (440) succinic semialdehyde dehydrogenase
M. abscessus ATCC 19977MAB_4484-2e-8841.89% (475) aldehyde dehydrogenase
M. marinum MMMAR_0472-1e-8439.38% (480) aldehyde dehydrogenase
M. avium 104MAV_3553-1e-11646.62% (474) aldehyde dehydrogenase
M. smegmatis MC2 155MSMEG_5815-1e-11648.00% (475) betaine aldehyde dehydrogenase
M. ulcerans Agy99MUL_1122-3e-8238.54% (480) aldehyde dehydrogenase
M. vanbaalenii PYR-1Mvan_0240-6e-9040.42% (475) betaine-aldehyde dehydrogenase

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_1907|M.gilvum_PYR-GCK          ---MVADPVTPIGLLIGTDRLTRTSLAPHPHIYPATGAPNATVALAGADE
MSMEG_5815|M.smegmatis_MC2_155      -MTSVVLPGDPIGSLIGDRRVTASSGGLHAHVYPATGLPNATVALAGAAE
MAV_3553|M.avium_104                MTATASSPPRTGALLIGTERITAASGGSHQHRYPGTGVPNATIPLAGHSE
TH_3419|M.thermoresistible__bu      VQRTLPDKLPAPRLVIGGGDVISTSGGVYEHHYAATGGVQAEVPLAGPAE
Mb2883c|M.bovis_AF2122/97           ---------------MSTTQLIN----------PATEEVLASVDHTDANA
MMAR_0472|M.marinum_M               ----MGEKTEYDKLFIGGKWTEPSTSEVIEVHCPATGEYVGKVPLAAAAD
MUL_1122|M.ulcerans_Agy99           ----MGEKTEYDKLFIGGRWTEPSTSEVIEVHCPATGEYVGKVPLAAAAD
Rv0223c|M.tuberculosis_H37Rv        ---MSDSATEYDKLFIGGKWTKPSTSDVIEVRCPATGEYVGKVPMAAAAD
MAB_4484|M.abscessus_ATCC_1997      -------MTNYDKLFIGGVWTEPATDQVIEVISPATGQKVGQCPLASPAD
Mvan_0240|M.vanbaalenii_PYR-1       MTQSTTFRTEWDKLFIGGKWVEPATSDVIEVHSPATGELVGKVPLASAAD
MLBr_02573|M.leprae_Br4923          --------------------------MSIATINPATGETVKTFTPTTQDE
                                                                     ..*         :    

Mflv_1907|M.gilvum_PYR-GCK          VGMAVSAAREAQR--EWITLGVDQRRDKLIDLADVVREHLGELAELNTLD
MSMEG_5815|M.smegmatis_MC2_155      VDAAVSAAWEAHR--EWVAHPADRRRDMLVGLADVVHEHLDELAGLNVHD
MAV_3553|M.avium_104                VDRAVHSAREAQR--EWISYPVDRRRDLLFGLADLLRDHFAELTELNVHD
TH_3419|M.thermoresistible__bu      VDAAVAAARAAFP--AWRDLDLNRRRDILQELARRLVADGERLGAIATLE
Mb2883c|M.bovis_AF2122/97           VDDAVQRARAAQR--RWARLAPAQRAAGLRAFAAAVQAHLDELAALEVAN
MMAR_0472|M.marinum_M               VDAAVAAARAAFDNGPWPSTPPKERATVIANALKLLEERKDHFAKLLADE
MUL_1122|M.ulcerans_Agy99           VDAAVAAARAAFDNGPWPSTPPKERATVIANALKLLEERKDHFAKLFADE
Rv0223c|M.tuberculosis_H37Rv        VDAAVAAARAAFDNGPWPSTPPHERAAVIAAAVKMLAERKDLFTKLLAAE
MAB_4484|M.abscessus_ATCC_1997      VDAAVSAARRAFDNGPWPRLTPHERQAVLQKAVSLLESRKDEICKAIADE
Mvan_0240|M.vanbaalenii_PYR-1       VDAACAAAREAFDNGPWPHMSPAERGEILGRAVKIMEERADELKFLLAAE
MLBr_02573|M.leprae_Br4923          VEDAIARAYARFDN--YRHTTFTQRAKWANATADLLEAEANQSAALMTLE
                                    *  *   *        :      .*          :           . :

Mflv_1907|M.gilvum_PYR-GCK          YGVP-ISYAGNAVMLDQ-FLRHFAGYVDKPHGSSTPVSGSSDVNLIER--
MSMEG_5815|M.smegmatis_MC2_155      YAVP-ISNAGTALLLER-FLRHFAGYADKPHGTSSPVSGSFDVNIIER--
MAV_3553|M.avium_104                YGVP-ISVAGNSVLTER-FVRYYAGYPDKLTGASTPVSGAFDVNIVER--
TH_3419|M.thermoresistible__bu      VGTPNLLASSSSAMAAD-WFTYYAGWIGRSAGEVVPVPAGGALDYVLD--
Mb2883c|M.bovis_AF2122/97           SGHPIVSAEWEAGHVRD-VLAFYAASPERLSGRQIPVAGG--VDVTFN--
MMAR_0472|M.marinum_M               TGQPPMTVETMHWMGSIGALNFFAGPAVDQVRWKEIRNGSYGQTIVHR--
MUL_1122|M.ulcerans_Agy99           TGQPPMTVETMHWMGSIGALNFFAGPAVDQVRWKEIRNGSYGQTIVHR--
Rv0223c|M.tuberculosis_H37Rv        TGQPPTIIETMHWMGSMGAMNYFAG-AADKVTWTETRTGSYGQSIVSR--
MAB_4484|M.abscessus_ATCC_1997      TGAPPMVIETLQWMGGFGAIQYYAN-AADAVKWKELRNGAYGQTLVTR--
Mvan_0240|M.vanbaalenii_PYR-1       TGQPPTIVDMMQYGAAMSSFQFYAG-AADKFTWQDIRDGVYGQTLVVR--
MLBr_02573|M.leprae_Br4923          MGKTLQSAKDEAMKCAK-GFRYYAEKAETLLADEPAEAAAVGASKALARY
                                     . .               . .:*              .           

Mflv_1907|M.gilvum_PYR-GCK          EPFGAVGVIAPWNGSLVVAASCVAPALAAGNAVVFKPSELAPLAALRFGE
MSMEG_5815|M.smegmatis_MC2_155      EPYGVVGVIAPWNGALAVAASCVAPALAAGNAVVFKPSELAPLAALRFGE
MAV_3553|M.avium_104                EPYGVVAVIAPWNGPLVVAGAAVAPALAAGNAVIFKPSELASLAPLRFGE
TH_3419|M.thermoresistible__bu      EPLGVIAAIIPWNGPLISIGMKVAPALAAGNCVVLKPPENAPFSALRFAE
Mb2883c|M.bovis_AF2122/97           EPMGVVGVITPWNFPMVIASWAIAPALAAGNAVLVKPAELTPLTTMRLGE
MMAR_0472|M.marinum_M               EPIGVVGAIVAWNVPLFLAINKLGPALLAGCTVVLKPAAETPLTANALAE
MUL_1122|M.ulcerans_Agy99           EPIGVVGAIVAWNVPLFLAINKLGPAPLAGCTVVLKPAAETPLTANALAE
Rv0223c|M.tuberculosis_H37Rv        EPVGVVGAIVAWNVPLFLAVNKIAPALLAGCTIVLKPAAETPLTANALAE
MAB_4484|M.abscessus_ATCC_1997      EPAGVVAAIAAWNVPLFLALNKIGPAFLAGCAVVLKPAAETPLSSFILAE
Mvan_0240|M.vanbaalenii_PYR-1       EPVGVVGAVTAWNVPFFLAANKLGPALLAGCTVVLKPAAETPLSVFAMAE
MLBr_02573|M.leprae_Br4923          QPLGVVLAVMPWNFPLWQTVRFAAPALMAGNVGLLKHASNVPQCALYLAD
                                    :* *.: .: .** .:       .**  **   :.* .  ..     :.:

Mflv_1907|M.gilvum_PYR-GCK          LCLEAGLPPGLVNILPA-AAEGGDALVRHAGIAKIHFTGGGHTARAILRA
MSMEG_5815|M.smegmatis_MC2_155      LCLVAGLPPGLVNILPA-ASDGGDALVRHPGIRKIHFTGGGTTARAVLRA
MAV_3553|M.avium_104                LCLEAGLPPGLVNVLPA-GPEGGEALVRHPGVGKVHFTGGHATAQQVLRA
TH_3419|M.thermoresistible__bu      LAAEAGLPPGVLNVIPG-GAEAGSALCSHPGVDKITFTGGGETARKVFAA
Mb2883c|M.bovis_AF2122/97           LAVEAGLDEDLLQVLPGKGTVVGERFVTHPDIRKIVFTGSTEVGKRVMAG
MMAR_0472|M.marinum_M               VFAEAGLPEGVLSVVPG-GVETGQALTSNPGVDLFTFTGSSAVGKEIGRR
MUL_1122|M.ulcerans_Agy99           VFAEAGLPEGVLSVVPG-GVETGQALTSNPGVDLFTFTGSSAVGKEIGRR
Rv0223c|M.tuberculosis_H37Rv        VFAEVGLPEGVLSVVPG-GIETGQALTSNPDIDMFTFTGSSAVGREVGRR
MAB_4484|M.abscessus_ATCC_1997      VFAEAGVPEGVLSVVPG-GAETGRALTNNPDVDVFSFTGSTAVGKEIAEI
Mvan_0240|M.vanbaalenii_PYR-1       MFVEAGLPEGVLSIVPG-GPETGQALTANPNLDKYTFTGSSGVGKEIAKI
MLBr_02573|M.leprae_Br4923          VIARGGFPEDCFQTLLI-SANGVEAILRDPRVAAATLTGSEPAGQAVGAI
                                    :    *.  . .. :   .      :  .. :    :**.  ..: :   

Mflv_1907|M.gilvum_PYR-GCK          AADNLTPVVTELGGKSANIIFDDADLDIAAVRSAHQGPLMQSGQSCACAS
MSMEG_5815|M.smegmatis_MC2_155      ATDNLTPVVTELGGKSANIIFPDADLGRAAALAAHQGPLMQSGQSCACAS
MAV_3553|M.avium_104                ASDNVTPVTAELGGKSAYLVFADADLDTAAVIAAHQGPLTQAGQSCACAS
TH_3419|M.thermoresistible__bu      AAQALTPVVLELGGKSANIVFPDADLDAAATMAVSAGLMMLSGQGCILPT
Mb2883c|M.bovis_AF2122/97           AAAQVKRVTLELGGKSANIVFHDCDLERAATTAP-AGVFDNAGQDCCARS
MMAR_0472|M.marinum_M               AAEMLKPCTLELGGKSAAILLEDVDLSTAVPMMVFSGIMN-TGQACVGQT
MUL_1122|M.ulcerans_Agy99           AAEMLKPCTLELGGKSAAILLEDVDLSTAVPMMVFSGIMN-TGQACVGQT
Rv0223c|M.tuberculosis_H37Rv        AAEMLKPCTLELGGKSAAIILEDVDLAAAIPMMVFSGVMN-AGQGCVNQT
MAB_4484|M.abscessus_ATCC_1997      AAKNLKKVTLELGGKSAAIVLEDADLAAALPMLVFSGLMN-AGQGCVNQT
Mvan_0240|M.vanbaalenii_PYR-1       AADKLKPCTLELGGKSAAIILEDADLDSTLPMLVFSGLMN-SGQACVGQT
MLBr_02573|M.leprae_Br4923          AGNEIKPTVLELGGSDPFIVMPSADLDAAVATAVTGRVQN-NGQSCIAAK
                                    *   :.  . ****... ::: . **  :             ** *   .

Mflv_1907|M.gilvum_PYR-GCK          RILVHEAVYEAFTERFIDVVESARIGDPLDPATVFGPVISAAALDRIVGV
MSMEG_5815|M.smegmatis_MC2_155      RILVHESVYDAFTEQFLAVIGAARVGDPFDPEVNFGPVISAGSLDRLLNV
MAV_3553|M.avium_104                RILVEASVYVSFVEKLVAQVQAATIGDPLRPDVMLGPVITEAAADRILGV
TH_3419|M.thermoresistible__bu      RLLVHDDVYDEMVTRVVAGADALTVGDPWQPTTMMGPLATAAQLERVTRA
Mb2883c|M.bovis_AF2122/97           RILVQRSVYDRFMELLEPAVHSIVVGDPGSRATEMGPLVSRAHRDKVAGY
MMAR_0472|M.marinum_M               RILAPRSRYEEIVEAVSAFVQALPVGPPSDPAAQIGSLISEKQRARVEGY
MUL_1122|M.ulcerans_Agy99           RILAPRSRYEEIVEAVSAFVQTLPVGPPSDPAAQIGSLISEKQRARVEGY
Rv0223c|M.tuberculosis_H37Rv        RILAPRSRYDEIVAAVTNFVTALPVGPPSDPAAQIGPLISEKQRTRVEGY
MAB_4484|M.abscessus_ATCC_1997      RVLAPRSRYDEVVDGIVGMVSLMGVGLPDDPATQVGPLITEKQRTRVEGY
Mvan_0240|M.vanbaalenii_PYR-1       RILAPRSRYDEVVEKLAAAAAGMAPGLPDNPAAMIGPLISEKQRDRVEGY
MLBr_02573|M.leprae_Br4923          RFIAHADIYDEFVEKFVARMETLRVGDPTDPDTDVGPLATESGRAQVEQQ
                                    *.:.    *  .   .         * *    . .*.: :     ::   

Mflv_1907|M.gilvum_PYR-GCK          VGEAVDSGSGDLLAGGRRLTEDSLAAGYYLEPTVLGNVDNTSPLAQTETF
MSMEG_5815|M.smegmatis_MC2_155      VHRAVEERAGELLVGGERLVDGALAGGFYMQPTVFGGVDNRSRLAQVETF
MAV_3553|M.avium_104                IERAVAEKAGDLVTGGRRLG-GELASGYFIEPTIFSNVDNRSSLAQTETF
TH_3419|M.thermoresistible__bu      VDSALSDKAGKLLAGGRRPD--GLDAGYFYRPTVFGDVDPASDLAQTEIF
Mb2883c|M.bovis_AF2122/97           VPDDAPVAFRGTAPAG---------RGFWFPPTVLTPK-RGDRTVTDEIF
MMAR_0472|M.marinum_M               IAKGIEEGAR-LVSGGGRPE--GLDNGFFVQPTVFADVDNKMTIAQEEIF
MUL_1122|M.ulcerans_Agy99           IAKGIEEGAR-LVSGGGRPE--SLDNGFFVQPTVFADVDNKMTIAQEEIF
Rv0223c|M.tuberculosis_H37Rv        IAKGIEEGAR-LVCGGGRPE--GLDNGFFIQPTVFADVDNKMTIAQEEIF
MAB_4484|M.abscessus_ATCC_1997      IAKGIAEGAR-LAYGGKRPE--GLDGGYFVQPTIFADVDNSMTIAQEEIF
Mvan_0240|M.vanbaalenii_PYR-1       IKKGIEEGAR-VVTGGGRPE--GLDSGWYVQPTVFADVDNSMTIAQEEIF
MLBr_02573|M.leprae_Br4923          VDAAAAAGAV-IRCGGKRPD----RPGWFYPPTVITDITKDMALYTDEVF
                                    :             .*          *::  **::            * *

Mflv_1907|M.gilvum_PYR-GCK          GPVVSLIPFADDDGAVRIANDTPYGLNAFVHTRDLTRAHTVARRLQSGSV
MSMEG_5815|M.smegmatis_MC2_155      GPVVSLIRFVDDDEAVRLANDTPYGLNAFVHTADLTRAHTVSRQLEAGSV
MAV_3553|M.avium_104                GPVASVMPFADEAQAVSLANDSRYGLNAFVATANLERAHRVARRLQAGSV
TH_3419|M.thermoresistible__bu      GPVLAILRFRSEEEAVELANNTQYGLAAYIHTRDLRRAHVMAAALDAGGV
Mb2883c|M.bovis_AF2122/97           GPVVVVLTFDDEADAISLANDTAYGLSGSIWTDDLSRALRVARAVESGNL
MMAR_0472|M.marinum_M               GPVLVVIPYDTEEDAIKIANDSVYGLAGSVWTSNVPKGIEISEKIRTGTY
MUL_1122|M.ulcerans_Agy99           GPVLVVIPYDTKEDAIKIANDSVYGLAGSVWTSNVPKGIEISEKIRTGTY
Rv0223c|M.tuberculosis_H37Rv        GPVLAIIPYDTEEDAIAIANDSVYGLAGSVWTTDVPKGIKISQQIRTGTY
MAB_4484|M.abscessus_ATCC_1997      GPVLSIIAYDSVDEAVKIANDSNYGLAGSVWTTDVQKGLEVAAQIRTGTY
Mvan_0240|M.vanbaalenii_PYR-1       GPVLAVIPYEDEDDAVRIANDSVYGLAGSVYTTDNDRALKIARRIRTGTY
MLBr_02573|M.leprae_Br4923          GPVASVYCATNIDDAIEIANATPFGLGSNAWTQNESEQRHFIDNIVAGQV
                                    ***  :        *: :** : :** .   * :  .   .   : :*  

Mflv_1907|M.gilvum_PYR-GCK          WINQGSRISPQGPYGGYKQSGSGRTGGLEGLREFQQVKNIRIGIG-----
MSMEG_5815|M.smegmatis_MC2_155      WVNQFSQISPQGPYGGYKQSGSGRTGGLDGLHEFQQIKNIRIGMG-----
MAV_3553|M.avium_104                WVNRHSDIEPQGPYGGYKQSGFGRTGGVEGLHEFLQVKNIRIGMS-----
TH_3419|M.thermoresistible__bu      AVNGFPIVPSAAPFGGVKQSGFGREGGIWGLREFQRTKNVYIGLQ-----
Mb2883c|M.bovis_AF2122/97           SVNSHSSVRFNTPFGGFKQSGVGRELGPDAPLQFTETKNVFIAVGEEM--
MMAR_0472|M.marinum_M               AIN-WYAFDPCCPFGGYKNSGIGRENGPEGVEHFTQQKSVLMPMGYTLES
MUL_1122|M.ulcerans_Agy99           AIN-WYAFDPCCPFGGYKNSGIGRENGPEGVEHFTQQKSVLMPMGYTLES
Rv0223c|M.tuberculosis_H37Rv        GIN-WYAFDPGSPFGGYKNSGIGRENGPEGVEHFTQQKSVLLPMGYTVA-
MAB_4484|M.abscessus_ATCC_1997      GIN-WYAFDPSCPFGGYKQSGIGRENGPEGIEEYCELKSVLLPMGYTLES
Mvan_0240|M.vanbaalenii_PYR-1       AVN-MYAFDPCAPFGGFKNSGIGRENGWEGIEAYCEPKSILLPFGYTPAT
MLBr_02573|M.leprae_Br4923          FINGMTVSYPELPFGGIKRSGYGRELSTHGIREFCNIKTVWIA-------
                                     :*         *:** *.** **  .  .   : . *.: :        

Mflv_1907|M.gilvum_PYR-GCK          -
MSMEG_5815|M.smegmatis_MC2_155      -
MAV_3553|M.avium_104                -
TH_3419|M.thermoresistible__bu      -
Mb2883c|M.bovis_AF2122/97           -
MMAR_0472|M.marinum_M               -
MUL_1122|M.ulcerans_Agy99           -
Rv0223c|M.tuberculosis_H37Rv        -
MAB_4484|M.abscessus_ATCC_1997      I
Mvan_0240|M.vanbaalenii_PYR-1       -
MLBr_02573|M.leprae_Br4923          -