For questions or suggestions e-mail us at: ioerger@cs.tamu.edu

M. thermoresistible (build 8) TH_4328 (-)

annotation: oxidoreductase, short chain dehydrogenase/reductase family protein
coordinates: 187737 - 188528
length: 264

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_4328--100% (264)oxidoreductase, short chain dehydrogenase/reductase family protein
M. thermoresistible (build 8)TH_2623-1e-3135.60% (250) PUTATIVE short-chain dehydrogenase/reductase SDR
M. thermoresistible (build 8)TH_3791-8e-3036.69% (248) PUTATIVE putative short-chain dehydrogenase/reductase SDR

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb0950c-1e-2632.38% (244) short chain dehydrogenase
M. gilvum PYR-GCKMflv_1783-1e-12685.77% (260) short-chain dehydrogenase/reductase SDR
M. tuberculosis H37RvRv0927c-1e-2632.38% (244) short chain dehydrogenase
M. leprae Br4923MLBr_02565fabG7e-2432.51% (243) 3-ketoacyl-(acyl-carrier-protein) reductase
M. abscessus ATCC 19977MAB_4632-7e-3033.47% (242) short chain dehydrogenase
M. marinum MMMAR_0302-1e-11076.92% (260) short-chain type dehydrogenase/reductase
M. avium 104MAV_5213-1e-12183.01% (259) oxidoreductase, short chain dehydrogenase/reductase family
M. smegmatis MC2 155MSMEG_5632-1e-12785.44% (261) oxidoreductase, short chain dehydrogenase/reductase family
M. ulcerans Agy99MUL_4820-3e-9472.31% (242) short-chain type dehydrogenase/reductase
M. vanbaalenii PYR-1Mvan_4967-1e-12584.67% (261) short-chain dehydrogenase/reductase SDR

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_1783|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_4967|M.vanbaalenii_PYR-1       --------------------------------------------------
TH_4328|M.thermoresistible__bu      --------------------------------------------------
MSMEG_5632|M.smegmatis_MC2_155      --------------------------------------------------
MAV_5213|M.avium_104                --------------------------------------------------
MMAR_0302|M.marinum_M               --------------------------------------------------
MUL_4820|M.ulcerans_Agy99           --------------------------------------------------
MLBr_02565|M.leprae_Br4923          MAPKCSSDLFSQIVSSGPGSFVAKQLGVPRPETLRRYRPSDAPLCGSLLI
Mb0950c|M.bovis_AF2122/97           --------------------------------------------------
Rv0927c|M.tuberculosis_H37Rv        --------------------------------------------------
MAB_4632|M.abscessus_ATCC_1997      --------------------------------------------------
                                                                                      

Mflv_1783|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_4967|M.vanbaalenii_PYR-1       --------------------------------------------------
TH_4328|M.thermoresistible__bu      --------------------------------------------------
MSMEG_5632|M.smegmatis_MC2_155      --------------------------------------------------
MAV_5213|M.avium_104                --------------------------------------------------
MMAR_0302|M.marinum_M               --------------------------------------------------
MUL_4820|M.ulcerans_Agy99           --------------------------------------------------
MLBr_02565|M.leprae_Br4923          GGDGRLVEPLRATLEKDYDLVSNNLGGRWTDSFGGLVFDATGITAPAELK
Mb0950c|M.bovis_AF2122/97           --------------------------------------------------
Rv0927c|M.tuberculosis_H37Rv        --------------------------------------------------
MAB_4632|M.abscessus_ATCC_1997      --------------------------------------------------
                                                                                      

Mflv_1783|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_4967|M.vanbaalenii_PYR-1       --------------------------------------------------
TH_4328|M.thermoresistible__bu      --------------------------------------------------
MSMEG_5632|M.smegmatis_MC2_155      --------------------------------------------------
MAV_5213|M.avium_104                --------------------------------------------------
MMAR_0302|M.marinum_M               --------------------------------------------------
MUL_4820|M.ulcerans_Agy99           --------------------------------------------------
MLBr_02565|M.leprae_Br4923          GLHNFFTPLLRNLGRCARVVVIGTTPDATTSTDERIAQRALEGFSRSLGK
Mb0950c|M.bovis_AF2122/97           --------------------------------------------------
Rv0927c|M.tuberculosis_H37Rv        --------------------------------------------------
MAB_4632|M.abscessus_ATCC_1997      --------------------------------------------------
                                                                                      

Mflv_1783|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_4967|M.vanbaalenii_PYR-1       --------------------------------------------------
TH_4328|M.thermoresistible__bu      --------------------------------------------------
MSMEG_5632|M.smegmatis_MC2_155      --------------------------------------------------
MAV_5213|M.avium_104                --------------------------------------------------
MMAR_0302|M.marinum_M               --------------------------------------------------
MUL_4820|M.ulcerans_Agy99           --------------------------------------------------
MLBr_02565|M.leprae_Br4923          ELRRGATVALVYLSPDAKPAATGLESTMRFILSAKSAYVNGQVFYVGAAD
Mb0950c|M.bovis_AF2122/97           --------------------------------------------------
Rv0927c|M.tuberculosis_H37Rv        --------------------------------------------------
MAB_4632|M.abscessus_ATCC_1997      --------------------------------------------------
                                                                                      

Mflv_1783|M.gilvum_PYR-GCK          ---------MQTAQVAIVTGASSGIGFGCATALADRGMVVLGTGRDAGRL
Mvan_4967|M.vanbaalenii_PYR-1       ------------MQVAIVTGASSGIGFGCATTLAEQGMAVLGTGRDPGRL
TH_4328|M.thermoresistible__bu      ----------VNMQVAIVTGASSGIGFGCATKLAEQGMAVLGTGRDSGRL
MSMEG_5632|M.smegmatis_MC2_155      ------------MQVAIITGASSGIGFGCATKLAEAGMAVLGVGRDKERL
MAV_5213|M.avium_104                ------------MQVAIVTGASSGIGLGCATRLAGTGMAVLGTGRDPKRL
MMAR_0302|M.marinum_M               ------------MQVAIITGATGGIGFGCAAKLAEMGMAVLGTGRDERRL
MUL_4820|M.ulcerans_Agy99           ------------MQVAIITAATGGIGFGCAAKFAEMSMAVVGTARDERRL
MLBr_02565|M.leprae_Br4923          STPPTNWDRPLENKVAIVTGAARGIGAAIAEVVARDGARVVAIDVESAAE
Mb0950c|M.bovis_AF2122/97           ---MILDMFRLDDKVAVITGGGRGLGAAIALAFAQAGADVLIASRTSSEL
Rv0927c|M.tuberculosis_H37Rv        ---MILDMFRLDDKVAVITGGGRGLGAAIALAFAQAGADVLIASRTSSEL
MAB_4632|M.abscessus_ATCC_1997      ---MILDRFKLDGNVAVVTGAGRGLGAAIAEAFAQAGADVLIASRTESQL
                                                 :**::*..  *:* . *  .*  .  *:         

Mflv_1783|M.gilvum_PYR-GCK          AELE----KAAPEPGRIATLAVDLTDDDAPQRIVSAALDRWG-RIDFLVN
Mvan_4967|M.vanbaalenii_PYR-1       AALE----KSS---DRIATLAVDLTDDDAPQRIVSAALERWG-RIDFLVN
TH_4328|M.thermoresistible__bu      AGLEKTLRKAGVPADRIATLAVDLTADEAPQRIVDAAVSRWG-HIDFLIN
MSMEG_5632|M.smegmatis_MC2_155      AELA----QTIDAPDRVATLALDLTDDDAPQRIVDAAVTRWG-KVDFLIN
MAV_5213|M.avium_104                AELE----TAIGDPDRVATVAVDLTDDDAPRRIVDRALQRWG-HIDFLIN
MMAR_0302|M.marinum_M               AELT----QLPGGPDRIATHPVDLTDDDAPGQLTRAALERWG-RIDFLIN
MUL_4820|M.ulcerans_Agy99           AELT----QLPGGPDRIATHPVDPTDDDAPGQLTRAALDRWG-RIDFLIN
MLBr_02565|M.leprae_Br4923          ALDET------ANRVGGTTLSLDVTADDAVDKITEHLHDYQGGHADILVN
Mb0950c|M.bovis_AF2122/97           DAVAE---QIRAAGRRAHTVAADLAHPEVTAQLAGQAVGAFG-KLDIVVN
Rv0927c|M.tuberculosis_H37Rv        DAVAE---QIRAAGRRAHTVAADLAHPEVTAQLAGQAVGAFG-KLDIVVN
MAB_4632|M.abscessus_ATCC_1997      REVAA---KVQAAGRQAEVVVADLSDTEASAALAQKAVDRFG-RLDVVVN
                                                      .   * :  :.   :.       * : *.::*

Mflv_1783|M.gilvum_PYR-GCK          NAGIGSPKPLHETDDETLDHFLGVMLRAPFRLARDVIVH--MQPGSA-II
Mvan_4967|M.vanbaalenii_PYR-1       NAGIGSPKPLHETDDETLDRFLDIMLRAPFRLARDVIVH--MQPGSA-II
TH_4328|M.thermoresistible__bu      NAGVGSPKPLGETDDDTLDHFLGLMLRAPFRLARDVLPH--MRPGSA-II
MSMEG_5632|M.smegmatis_MC2_155      NAGVGSPKPLHETDDESLDYFLGLMLRAPFRLARDVIPH--MGPGSA-II
MAV_5213|M.avium_104                NAGVGSPKPLHETDDETLDYFLNLMLRAPFRLAREVLPH--LPPGSA-II
MMAR_0302|M.marinum_M               AAGVGSPKPVHETDDESLDYVLSLMLRAPFRLTREVLPH--LRPGSA-II
MUL_4820|M.ulcerans_Agy99           AAGEGSPKSVHETDDESLDYVLSLMLRAPFRLTREVLPH--LRPGSA-II
MLBr_02565|M.leprae_Br4923          NAGITRDKLLANMDDCRWDAVLEVNLLAPQRLTEGLVGNGSISKGGR-VI
Mb0950c|M.bovis_AF2122/97           NVGGTMPNTLLSTSTKDLADAFAFNVGTAHALTVAAVPLMLEHSGGGSVI
Rv0927c|M.tuberculosis_H37Rv        NVGGTMPNTLLSTSTKDLADAFAFNVGTAHALTVAAVPLMLEHSGGGSVI
MAB_4632|M.abscessus_ATCC_1997      NVGGTMPKPFLDTTNDDLAEAFSFNVLSGHALLRAAVPHLLK-SDNASVI
                                     .*    : . .         : . : :   *    :       ..  :*

Mflv_1783|M.gilvum_PYR-GCK          NVTSTFAVVGGLRGGAYSAAKGGLTALTSHIACQYGAQGIRCNAVAPGVT
Mvan_4967|M.vanbaalenii_PYR-1       NITSTFAVVGGLRGGAYSAAKGGLTALTTHIACQYGAQGIRCNAVAPGVT
TH_4328|M.thermoresistible__bu      NITSTFAVVGGLRGGAYSAAKGGLTALTTHIACQYGAQGIRCNAVAPGVT
MSMEG_5632|M.smegmatis_MC2_155      NVTSTFAVVGGLRGGAYSAAKGGLTALTTHIACQYGAQGIRCNAVAPGVT
MAV_5213|M.avium_104                NVTSTFAVVGGLRGGAYSAAKGGLTALTTHIACQYGASGIRCNAVAPGVT
MMAR_0302|M.marinum_M               NITSTFAVVGGLRGGAYSAAKGGLTALTTHIACQYGAQGIRCNAVAPGVI
MUL_4820|M.ulcerans_Agy99           NITSTFAVVGGLRGGAYSAAKGGLAALTTHIACQYGAQGIRCNAVAPGVI
MLBr_02565|M.leprae_Br4923          VLSSMAGIAGNRGQTNYATAKAGVIGLTQALAPGLAEKGITINAVAPGFI
Mb0950c|M.bovis_AF2122/97           NISSTMGRLAARGFAAYGTAKAALAHYTRLAALDLCPR-VRVNAIAPGSI
Rv0927c|M.tuberculosis_H37Rv        NISSTMGRLAARGFAAYGTAKAALAHYTRLAALDLCPR-VRVNAIAPGSI
MAB_4632|M.abscessus_ATCC_1997      NITSTMGRLPGRAFLGYCTAKGALAHYTRTAAMDLSPR-IRVNGIAPGSI
                                     ::*  .         * :**..:   *   *       :  *.:***  

Mflv_1783|M.gilvum_PYR-GCK          LTPMVATRLEDERFRKINTEMTPHQRLGRVEDIASTVAFLCSDGGEFING
Mvan_4967|M.vanbaalenii_PYR-1       LTPMVASRLEDERFRKINTEMTPHQRLGRVEDVASTVAFLCSEGGSFING
TH_4328|M.thermoresistible__bu      LTPMVATRLEDERFRKINTEMTPHQRLGRVEDIAATVAFLCSPGAEFING
MSMEG_5632|M.smegmatis_MC2_155      LTPMVATRLEDDRFRKINTEMTPHQRLGRVEDVASTVAFLCSEGGSFING
MAV_5213|M.avium_104                VTPMVENRLQDPRFRKINTEMTPHQRLGSVDDIAATVAFLCSPGGSFING
MMAR_0302|M.marinum_M               QTAMTQHRLADERFRRINVEMTPHQRLGTVDDVANTVAFLCSEGGAFING
MUL_4820|M.ulcerans_Agy99           QTAMTQHRLADERFRRLNVEITPHQRLGTVDDVANTVAFLCSEGGAFING
MLBr_02565|M.leprae_Br4923          ETQMTAAIPLAT--REVGRRLNSLLQGGLPVDVAETIAYFAIPASNAVTG
Mb0950c|M.bovis_AF2122/97           LTSALEVVAANDELRAPMEQATPLRRLGDPVDIAAAAVYLASPAGSFLTG
Rv0927c|M.tuberculosis_H37Rv        LTSALEVVAANDELRAPMEQATPLRRLGDPVDIAAAAVYLASPAGSFLTG
MAB_4632|M.abscessus_ATCC_1997      LTSALEVVAGNDEMRNTLEQNTPLHRLGDPADIAAAAVYLASPAGSFLTG
                                     *            *    . ..  : *   *:* : .::.  ..  :.*

Mflv_1783|M.gilvum_PYR-GCK          QTIVVDGGWSSTKYLSDFALNSEWVARQGTS-
Mvan_4967|M.vanbaalenii_PYR-1       QTIVVDGGWSTTKYLSDFALNAHWVER-----
TH_4328|M.thermoresistible__bu      QTIVVDGGWSSTKYLSDHALTSEWVPR-----
MSMEG_5632|M.smegmatis_MC2_155      QTIVVDGGWSSTKYLSDHALNSDWVPR-----
MAV_5213|M.avium_104                QTIVVDGGWSSTKYLSEYALTSEWIAP-----
MMAR_0302|M.marinum_M               QTIVVDGGWSSTKYLSDFALTAQWSPAQDDSK
MUL_4820|M.ulcerans_Agy99           QTIVVDGG------------------------
MLBr_02565|M.leprae_Br4923          NVIRVCGQAMLGA-------------------
Mb0950c|M.bovis_AF2122/97           KTLEVDGGLTFPNLDLPIPDL-----------
Rv0927c|M.tuberculosis_H37Rv        KTLEVDGGLTFPNLDLPIPDL-----------
MAB_4632|M.abscessus_ATCC_1997      KVLEVDGGLIAPNLDIPLPDLA----------
                                    :.: * *