For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
aa seq not available
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. thermoresistible (build 8) | TH_4274 | - | - | 100% (417) | virulence factor Mce family protein |
| M. thermoresistible (build 8) | TH_4469 | - | e-140 | 60.77% (413) | PUTATIVE virulence factor Mce family protein |
| M. thermoresistible (build 8) | TH_4453 | - | e-138 | 59.95% (407) | PUTATIVE virulence factor Mce family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0606 | mce2C | 1e-56 | 34.88% (453) | MCE-family protein MCE2C |
| M. gilvum PYR-GCK | Mflv_2103 | - | 1e-145 | 61.05% (421) | virulence factor Mce family protein |
| M. tuberculosis H37Rv | Rv1968 | mce3C | 1e-159 | 67.25% (403) | MCE-family protein MCE3C |
| M. leprae Br4923 | MLBr_02591 | mce1C | 3e-50 | 32.69% (413) | putative secreted protein |
| M. abscessus ATCC 19977 | MAB_4151c | - | 5e-56 | 36.96% (349) | MCE-family protein |
| M. marinum M | MMAR_2884 | mce3C | 1e-157 | 65.94% (414) | MCE-family protein Mce3C |
| M. avium 104 | MAV_2534 | - | 1e-143 | 60.24% (425) | virulence factor Mce family protein |
| M. smegmatis MC2 155 | MSMEG_0348 | - | 1e-156 | 65.29% (412) | mce-family protein mce3c |
| M. ulcerans Agy99 | MUL_3920 | mce3C_1 | 1e-141 | 60.20% (407) | MCE-family protein, Mce3C_1 |
| M. vanbaalenii PYR-1 | Mvan_3980 | - | 1e-163 | 68.95% (409) | virulence factor Mce family protein |
CLUSTAL 2.0.9 multiple sequence alignment
Rv1968|M.tuberculosis_H37Rv ----MKSFAERNRLAIGTVGIVVVAAVALAALQYQRLPFFNQGTRVSAYF
MMAR_2884|M.marinum_M ----MKSFAERNLLLVGTVGILTAAGVVGGALQYQKLPFFDQGTSVCAYF
Mvan_3980|M.vanbaalenii_PYR-1 ----MKSFAERSPLAIGIVGAAAVSAVVVGALQYQNLPLVNQVNSYSAYF
TH_4274|M.thermoresistible__bu ----VKSFSERNLLVVGLVGMATVTALALVALNFQKIPVFNQGRSHVAEF
MSMEG_0348|M.smegmatis_MC2_155 MRAEMKAFSERDPRTIGLVGIAITVVIALAALNFDKLPLLSSTKGYSAYF
Mflv_2103|M.gilvum_PYR-GCK ----MKPFSERNQLVIGAVGVGITAAIVLGATNYDKIPLFDPGREYTAHF
MUL_3920|M.ulcerans_Agy99 ----MKSFAERNQIVVGAVELAITIGIVVGSLQYDKLPLFQSGKQYSACF
MAV_2534|M.avium_104 ----MKTFSERNPFIIGAIGLGAVFTLMLVSLNYDKLPFFHSDRTYSAYF
MAB_4151c|M.abscessus_ATCC_199 MPSKMSDIQEKDPVRTGIFGIAVVSMLVLVAFGYTGLPFWPQGKQYTGYF
Mb0606|M.bovis_AF2122/97 ----MRTLTEFNRGRVGMMGAVVTVLVVGVAQSFTSVPMLFATPTYYAQF
MLBr_02591|M.leprae_Br4923 ----MRTLELPNRLRSGLIGVLVVLLIIGVGQSFTSVPILFARPSYYGQF
: : . * . . : . : :*. . *
Rv1968|M.tuberculosis_H37Rv ADAGGLRTGNTVEVSGYPVGKVSSISLDGPGVLVEFKVDTDVRLGNRTEV
MMAR_2884|M.marinum_M ADVGGLRTGNTVEVSGYPVGKVSSIELDEPGARVTFKVDKNIRLGERTEA
Mvan_3980|M.vanbaalenii_PYR-1 ADAGGLFTGATVEVSGYPAGRVSDIELDGAAVLVRFTVDKNITMGELTEA
TH_4274|M.thermoresistible__bu ADAGGLYIGATVEVSGYPAGRVARIDLDGSRVVVAFTVDRDIHLGEKSEA
MSMEG_0348|M.smegmatis_MC2_155 ADAGGLNTGATVRVSGFAVGKVERIRLDGRKVLVDFTVDSAIHLGEQSEA
Mflv_2103|M.gilvum_PYR-GCK AEAGGLTTDAAVQVSGFKVGQVKSIELDGPQVLVTFTVDKGIRLGDRTEA
MUL_3920|M.ulcerans_Agy99 ADAGGLTTGVRVQVSGFRVGEVSSIELDGPQVLVKFTVDKHIRLGDHTEA
MAV_2534|M.avium_104 AEAGGLEPGNHVQISGYRVGQVDSVELDGPRVLVTFTVASNLRLGERTEA
MAB_4151c|M.abscessus_ATCC_199 ADSGGLESGGNVFVSGIKVGQVKDVSLAGNKVRVDFTVDRSIRLGDQSLA
Mb0606|M.bovis_AF2122/97 ADMGGINTGDKVEIAGVNVGLVRSLAIRGNRVLIGFSLP-GKTIGMQSRA
MLBr_02591|M.leprae_Br4923 TDTGGLNKGDKVRIAGMDVGKVEALKIDGDHVVIKFSIG-TNRIGTASRL
:: **: . * ::* .* * : : . : *.: :* :
Rv1968|M.tuberculosis_H37Rv AIKTKGLLGSKFLDVTPRGDG--RLDSPIPIERTTSPYQLPDALGDLAAT
MMAR_2884|M.marinum_M AIKTKGLLGSKFVEVIPRGEG--HLTGPIPVERTMSPYQLPDALGDLAST
Mvan_3980|M.vanbaalenii_PYR-1 GIKTKSLLGTKMLAVIPHGGG--RLDGPIPMSRTVSPYQLPDALGDLADT
TH_4274|M.thermoresistible__bu RIRAKSLLGTKVLEVLPRGEE--PLDAPIPLSRTTSPYQLPDALGDLAST
MSMEG_0348|M.smegmatis_MC2_155 AIKVKSLLGTKVIDVIPRGGG--QLHEPIPLERTTSPYQLPDALGDLATT
Mflv_2103|M.gilvum_PYR-GCK AIKTKGLLGTKILEVIARGEG--QQDGTIPIDRTTSPYQLPDALGELSAT
MUL_3920|M.ulcerans_Agy99 AIKTRGLLGTKMLEVISRGDG--QLQGTIPLDRTRSPYQLPDALGDLATT
MAV_2534|M.avium_104 AIKLRTVLGSKVLEVSPRGEG--QLTGPIPLQRTTSAYQLPDALGDLTAT
MAB_4151c|M.abscessus_ATCC_199 AIRTTTVLGEKSLSVTPAGAG--RIT-EIPLGRTTTPYTLNSALSDLGAS
Mb0606|M.bovis_AF2122/97 AIRTDTILGRKNLEIEPRGSEPLKPNGFLPLAQTTTPYQIYDAFVDVTKA
MLBr_02591|M.leprae_Br4923 GIRTDTVLGKKVLEVETRGTQLLRPGDSLPLGQSTTPYQSYDAFFDATKV
*: :** * : : . * :*: :: :.* .*: :
Rv1968|M.tuberculosis_H37Rv ISGLHTERLSESLATLAQTFADTPAHFRNAIHGVARLAQTLDERDNQLRS
MMAR_2884|M.marinum_M ISGLNTGQLSESLDTLAQTFADTPADFRNAVQGVARLARTLNQRDVQLRS
Mvan_3980|M.vanbaalenii_PYR-1 ISGLDTDQLSDSLSTVSEAFAHTPEELRDAVQGVARFAQTLNERDAQLRK
TH_4274|M.thermoresistible__bu ISDLETDQLSESLATLSETFAHTPEQLKRAVAGVGRIAQTLGERDTNLRN
MSMEG_0348|M.smegmatis_MC2_155 VENLNTDDLSAALDTMAQTFAGTPPDVKIAVAGVARLSETINKRDTELRN
Mflv_2103|M.gilvum_PYR-GCK ISGLDTDQLSESLRVLSATFADTPPQLKIAVEGVARFSDTLNARDAQLRG
MUL_3920|M.ulcerans_Agy99 ISGLNTNQLSDSLRVLADTFSDTPPQLRVAIEGVARFSQTLDERDAQLRG
MAV_2534|M.avium_104 ISGLNTDQLSKSLAVLANTFTDTPPDLKAAVQGVARFSQTLDERDGQLRT
MAB_4151c|M.abscessus_ATCC_199 AGGIDKAQLDQSLQVITEAMRDATPQLRGALDGVASLSRTLNARDAALEQ
Mb0606|M.bovis_AF2122/97 ATGWDIDAVKRSLNVLSETFDQTAPHLSAALEGVKAFSDTVGRRGEQIEQ
MLBr_02591|M.leprae_Br4923 ASGWNIDTIKQSLKVVSETIDQTYPHLSAALDGVAKFSDTIGARDKEIKH
. . :. :* .:: :: : .. *: ** :: *:. *. :.
Rv1968|M.tuberculosis_H37Rv LLANAAKATGVLANRTDQIVGLVRDTNVVLAQLRTQSAALDRIWANISAV
MMAR_2884|M.marinum_M LLDNAARATGVLANRTDQIAGLVRDTNALLVQLRTQSAALDQIWANISAV
Mvan_3980|M.vanbaalenii_PYR-1 LLDDAAKATGVLAHRSDQVARLISDTNALLAQLRTQSDAVNQIWVNISAA
TH_4274|M.thermoresistible__bu LLDNAAAATGVLARRTDQVVALVRESNNLLAELRMQSAALDQIWHSLSAA
MSMEG_0348|M.smegmatis_MC2_155 LLANARKATAVLATRTDQVVGLVQDSNALLAELRTQSDALDRVSQDISRA
Mflv_2103|M.gilvum_PYR-GCK LLANANKATTVLAERSEQVVGLVSNTNALLAELQNQSAAVDQISGNISAL
MUL_3920|M.ulcerans_Agy99 LLTNANKATTVLAERSNQVVSLIANTNALLAELTTQRAALDHISGNIAAL
MAV_2534|M.avium_104 LLSNANKATTVLAERSDEVAKLVRDTNALLRQLRSQSSALEQISNNLAAL
MAB_4151c|M.abscessus_ATCC_199 LLTHAKSVSGILSERAGQVNKLVTDGNQLFAALDERRLAISELINRIQGL
Mb0606|M.bovis_AF2122/97 LLANANRIARVLGDRSEQVNGLLVNAKTLLAAFKQRSQALRILLTNVSEA
MLBr_02591|M.leprae_Br4923 LIAQANQVASVLGDRGAQVDRLLVNTKTLIAAFNERGRAVDALLGNVAAF
*: .* : :*. * :: *: : : :: : : *: : :
Rv1968|M.tuberculosis_H37Rv AEQLRGFIAENRQQLRPALDKLNGVLAIVENRKERVRQAIPLINTYVMSL
MMAR_2884|M.marinum_M ARQLKGFIADNRQELRPALDKLNGVLDIVEARKERLQQAIPLINTYVMSL
Mvan_3980|M.vanbaalenii_PYR-1 AQQLKGFIAENRQQLRPALDKLNGVLAIVDNRKERLQEAVKLLNKYAMSL
TH_4274|M.thermoresistible__bu ARQLEGFIDENRTELRPALEKLNGVLTIIDNRKERVQLALEGLHTYALAL
MSMEG_0348|M.smegmatis_MC2_155 ATQLRGFMADNRQQLRPMLDKLNGVLTIVDNRKDRLQEAVKLLNKYALSL
Mflv_2103|M.gilvum_PYR-GCK SAQLQGFIGENRDTMKPALDKLNGVLTILDNRKERLQKSLSLLNDYSMSL
MUL_3920|M.ulcerans_Agy99 GQQLHGLIAENEATMRPALDKLNGVLTILDNRKERLQKAIKLLDDYTMSL
MAV_2534|M.avium_104 ARQLKGFIAENRDTLKPALDKLNSVLAIVDNRKENVQKALVGLNKYALGL
MAB_4151c|M.abscessus_ATCC_199 SQQISGFVADNRQEFRPTMEKLSVVLDDLLDRKAHISEALKRLPGYGTAL
Mb0606|M.bovis_AF2122/97 SAQVSGLITDN-PNLNHVLAQLRTVSEELVKRKNELADVAVLLGRYTAAL
MLBr_02591|M.leprae_Br4923 AAQVQRLINDN-PNLNHVLEQLHQLSGILVQHKDDLANTLIQVAAFLPSL
. *: :: :* :. : :* : : :* : : : .*
Rv1968|M.tuberculosis_H37Rv GESLSSGPFFKAYVVNLLPGQFVQPFISAAFSDLGLDPATLLPSQ-----
MMAR_2884|M.marinum_M GESVSSGPFFKAYVVNLLPGQFVQPFIGAAFSDLGLDPATLLPSQ-----
Mvan_3980|M.vanbaalenii_PYR-1 GESLSSGPFFKAYVANLLPGQFVQPFVDAAFSDLGLDPNVLPPSQ-----
TH_4274|M.thermoresistible__bu GESLGSGPFFKAYLSNLLPGQFVQPFVEAAFSDLGLDPAVLAPSE-----
MSMEG_0348|M.smegmatis_MC2_155 GESVGSGPFFKAYIPNLIPGQFSQPFIDAAFSDLGLDPATLLPSQ-----
Mflv_2103|M.gilvum_PYR-GCK GESVSAGPFFKTYVANLLPGQFLQPFIDVAFSDLGLDPNVLLPSQ-----
MUL_3920|M.ulcerans_Agy99 GESVSSGPFFKTYVANLAPGQFVQPFIDAAFSDLGLDPNVLLPSQ-----
MAV_2534|M.avium_104 GESVSSGPFFKAYVVNLFPGQFVQPFIDAAFSDLGLDPNVLLPSQ-----
MAB_4151c|M.abscessus_ATCC_199 GEVVSSGPGFHVNVYGFPPATLTAVAFDTYF-------------------
Mb0606|M.bovis_AF2122/97 TEAVGSGPFFKAMVVNLLPYQILQPWVDAAFKKRGIDPENFWRSAGLPEF
MLBr_02591|M.leprae_Br4923 NEAIGSGPFFKVVLHNLAPYQILQPWVDAAFKKRGIDPENFWRSAGLPEF
* :.:** *:. : .: * : . . *
Rv1968|M.tuberculosis_H37Rv --LTDPPTGQPGTPPLPMPYPRTGQGGEPRLTLPDAITGNPGDP------
MMAR_2884|M.marinum_M --LTDPPTGQPGTPPLPMPYPRTGQGGEPRLTLPDAITGNPGDP------
Mvan_3980|M.vanbaalenii_PYR-1 --LTDPQTGQPGTPALPVPYPRTGQGGEPHLNLPDAITGKPGDP------
TH_4274|M.thermoresistible__bu --LSDPQTGRPGTPALPVPYPRTGQGGEPRTTVPDAITGKPGDP------
MSMEG_0348|M.smegmatis_MC2_155 --LVDPPVGQPGTPALPVPYPRTGQGGEPRLNLPDAITGNPGDP------
Mflv_2103|M.gilvum_PYR-GCK --RSDPQVGQPGTPAMPVPFPRTGQGGEPRMTIPDAITGNPGDAGCGPPG
MUL_3920|M.ulcerans_Agy99 --RTDPPIGQPGTPPLPLPFPRTGQGGEPHRKLPDAITGNPDDP------
MAV_2534|M.avium_104 --RADPQVGQPATPPLPMPFPRTGQGGEPRMTLPDAITGNPGDHPCGSPG
MAB_4151c|M.abscessus_ATCC_199 ---------QPGKLPASLSDYLNGLIGERQIMRPKSP-------------
Mb0606|M.bovis_AF2122/97 RWPDPNGTRFPNGAPPAAPPVREGTPKHPGPAVPPGTPCSYTPAAG----
MLBr_02591|M.leprae_Br4923 RFPDPNGTRFPNGAPPPAPPVLEGTPENPGPAVPPGSPCSYTPAHPGGNN
* . . . * . * .
Rv1968|M.tuberculosis_H37Rv --------RYPYRPEPPAPPPGGPPPGP-------------PAQQPGDQP
MMAR_2884|M.marinum_M --------RYPYREPPPAPPPGGPPPGPPAVAPPGLASTPGPVQVPAPQP
Mvan_3980|M.vanbaalenii_PYR-1 --------RYPYREPLPAPAPGGPPPGP-------------PALQPVGPR
TH_4274|M.thermoresistible__bu --------HYPYRQPPPAPEPGGPPPGPP-----------APAAPASEES
MSMEG_0348|M.smegmatis_MC2_155 --------RYPYREPPPAPAPGGPPPGPPAPPVPGLESTPSPTPSPVYVP
Mflv_2103|M.gilvum_PYR-GCK IPLPGPTGCYPYREPLPAPPPGGPPPGPPAVSPPGLASTPTPDTG-LLVP
MUL_3920|M.ulcerans_Agy99 --------RYPYREPLPAPPPGGPPPGPPAPAPPELASIPQPTPSSVLVP
MAV_2534|M.avium_104 AASSGP-GCYPYREPLPAPPPGGPPPGPPAQ-PGQGAGQSAPLPG----P
MAB_4151c|M.abscessus_ATCC_199 --------------------------------------------------
Mb0606|M.bovis_AF2122/97 ------ALPRPDNPLPCAGATVGPFGGPDFPAPLDVQPSPPNPDGPPPTP
MLBr_02591|M.leprae_Br4923 TIGDEMGLPRPWNPLPCAGATAGPYGGPAFPAPIDVQTSPPNPDGLPLLP
Rv1968|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_2884|M.marinum_M GGPS----------------------------------------------
Mvan_3980|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_4274|M.thermoresistible__bu GGRQ----------------------------------------------
MSMEG_0348|M.smegmatis_MC2_155 APGEPT--TPIPAGEGR---------------------------------
Mflv_2103|M.gilvum_PYR-GCK APGEAPPLVPVPGEGTR---------------------------------
MUL_3920|M.ulcerans_Agy99 APGEVS--APQTAGAGR---------------------------------
MAV_2534|M.avium_104 AQ-------PGEGGEGR---------------------------------
MAB_4151c|M.abscessus_ATCC_199 --------------------------------------------------
Mb0606|M.bovis_AF2122/97 GILSAGRPGEPAPAVPGIPMPLPPNAPPGARTQPLEP-------------
MLBr_02591|M.leprae_Br4923 GIAIAGRPGDPAPNVPGTPVPLPPNAPPGARTEQLAPAAPAQDSSAPHEP
Rv1968|M.tuberculosis_H37Rv -------------------------
MMAR_2884|M.marinum_M -------------------------
Mvan_3980|M.vanbaalenii_PYR-1 -------------------------
TH_4274|M.thermoresistible__bu -------------------------
MSMEG_0348|M.smegmatis_MC2_155 -------------------------
Mflv_2103|M.gilvum_PYR-GCK -------------------------
MUL_3920|M.ulcerans_Agy99 -------------------------
MAV_2534|M.avium_104 -------------------------
MAB_4151c|M.abscessus_ATCC_199 -------------------------
Mb0606|M.bovis_AF2122/97 ---------FPDGTGGSNQ------
MLBr_02591|M.leprae_Br4923 REQLSAPLINPGGTGGSGGAGGSRN