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aa seq not available
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. thermoresistible (build 8) | TH_4453 | - | - | 100% (442) | virulence factor Mce family protein |
| M. thermoresistible (build 8) | TH_3264 | - | e-150 | 62.74% (424) | PUTATIVE virulence factor Mce family protein |
| M. thermoresistible (build 8) | TH_4469 | - | e-144 | 62.19% (402) | PUTATIVE virulence factor Mce family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0606 | mce2C | 7e-62 | 34.00% (447) | MCE-family protein MCE2C |
| M. gilvum PYR-GCK | Mflv_0650 | - | 1e-157 | 61.61% (435) | virulence factor Mce family protein |
| M. tuberculosis H37Rv | Rv1968 | mce3C | 1e-153 | 66.01% (406) | MCE-family protein MCE3C |
| M. leprae Br4923 | MLBr_02591 | mce1C | 9e-57 | 31.51% (403) | putative secreted protein |
| M. abscessus ATCC 19977 | MAB_4151c | - | 3e-60 | 37.25% (357) | MCE-family protein |
| M. marinum M | MMAR_4053 | mce3C_1 | 1e-157 | 63.26% (430) | MCE-family protein, Mce3C_1 |
| M. avium 104 | MAV_2534 | - | 1e-149 | 60.96% (438) | virulence factor Mce family protein |
| M. smegmatis MC2 155 | MSMEG_0348 | - | 1e-151 | 60.58% (449) | mce-family protein mce3c |
| M. ulcerans Agy99 | MUL_3920 | mce3C_1 | 1e-155 | 62.56% (430) | MCE-family protein, Mce3C_1 |
| M. vanbaalenii PYR-1 | Mvan_0515 | - | 1e-157 | 61.61% (435) | virulence factor Mce family protein |
CLUSTAL 2.0.9 multiple sequence alignment
Rv1968|M.tuberculosis_H37Rv ----MKSFAERNRLAIGTVGIVVVAAVALAALQYQRLPFFNQGTRVSAYF
MSMEG_0348|M.smegmatis_MC2_155 MRAEMKAFSERDPRTIGLVGIAITVVIALAALNFDKLPLLSSTKGYSAYF
TH_4453|M.thermoresistible__bu VCTEMKPFAERNKRVMGAVGIGVGTIIIAGALQYDNLPVVSSDTRYSAYF
MMAR_4053|M.marinum_M ----MKSFAERNQIVVGAVGLAITIGIVVGSLQYDKLPFFQSGKQYSAYF
MUL_3920|M.ulcerans_Agy99 ----MKSFAERNQIVVGAVELAITIGIVVGSLQYDKLPLFQSGKQYSACF
Mflv_0650|M.gilvum_PYR-GCK ----MKTFSERNVIVIGAIGVLLTAAIVAGALNYNKLPFVSSGKSYSAYF
Mvan_0515|M.vanbaalenii_PYR-1 ----MKTFSERNVIVIGAIGVLLTAAIVAGALNYNKLPFVSSGKSYSAYF
MAV_2534|M.avium_104 ----MKTFSERNPFIIGAIGLGAVFTLMLVSLNYDKLPFFHSDRTYSAYF
MAB_4151c|M.abscessus_ATCC_199 MPSKMSDIQEKDPVRTGIFGIAVVSMLVLVAFGYTGLPFWPQGKQYTGYF
Mb0606|M.bovis_AF2122/97 ----MRTLTEFNRGRVGMMGAVVTVLVVGVAQSFTSVPMLFATPTYYAQF
MLBr_02591|M.leprae_Br4923 ----MRTLELPNRLRSGLIGVLVVLLIIGVGQSFTSVPILFARPSYYGQF
* : : * . : . : :*. . *
Rv1968|M.tuberculosis_H37Rv ADAGGLRTGNTVEVSGYPVGKVSSISLDGPGVLVEFKVDTDVRLGNRTEV
MSMEG_0348|M.smegmatis_MC2_155 ADAGGLNTGATVRVSGFAVGKVERIRLDGRKVLVDFTVDSAIHLGEQSEA
TH_4453|M.thermoresistible__bu AESGGLRAGAAVQVSGMRVGKVSAVELDGPHVRVEFRVRPNIRLGELSEA
MMAR_4053|M.marinum_M ADAGGLTTGVRVQVSGFRVGEVSSIELDGPRVLVKFTVDKHIRLGDHTEA
MUL_3920|M.ulcerans_Agy99 ADAGGLTTGVRVQVSGFRVGEVSSIELDGPQVLVKFTVDKHIRLGDHTEA
Mflv_0650|M.gilvum_PYR-GCK DEAGGLTTGAPVRVSGAPAGQVQSITLDGQWVLVTFTVADGIRLGDRTEA
Mvan_0515|M.vanbaalenii_PYR-1 DEAGGLTTGAPVRVSGAPAGQVQSITLDGQWVLVTFTVADGIRLGDRTEA
MAV_2534|M.avium_104 AEAGGLEPGNHVQISGYRVGQVDSVELDGPRVLVTFTVASNLRLGERTEA
MAB_4151c|M.abscessus_ATCC_199 ADSGGLESGGNVFVSGIKVGQVKDVSLAGNKVRVDFTVDRSIRLGDQSLA
Mb0606|M.bovis_AF2122/97 ADMGGINTGDKVEIAGVNVGLVRSLAIRGNRVLIGFSLP-GKTIGMQSRA
MLBr_02591|M.leprae_Br4923 TDTGGLNKGDKVRIAGMDVGKVEALKIDGDHVVIKFSIG-TNRIGTASRL
: **: * * ::* .* * : : * * : * : :* :
Rv1968|M.tuberculosis_H37Rv AIKTKGLLGSKFLDVTPRGDG--RLDSPIPIERTTSPYQLPDALGDLAAT
MSMEG_0348|M.smegmatis_MC2_155 AIKVKSLLGTKVIDVIPRGGG--QLHEPIPLERTTSPYQLPDALGDLATT
TH_4453|M.thermoresistible__bu AIKTKSLLGAKILDITSRGEG--RLSASIPVERTVSPYELPDALGDLAST
MMAR_4053|M.marinum_M AIKTRGLLGTKMLEVISRGDG--QLQGTIPLDRTRSPYQLPDALGDLATT
MUL_3920|M.ulcerans_Agy99 AIKTRGLLGTKMLEVISRGDG--QLQGTIPLDRTRSPYQLPDALGDLATT
Mflv_0650|M.gilvum_PYR-GCK SIKTTSVLGNKVLDLTTRGAG--TLAGTIPVERTTSPYQLPDAIGDLTTT
Mvan_0515|M.vanbaalenii_PYR-1 SIKTTSVLGNKVLDLTTRGAG--TLAGTIPVERTTSPYQLPDAIGDLTTT
MAV_2534|M.avium_104 AIKLRTVLGSKVLEVSPRGEG--QLTGPIPLQRTTSAYQLPDALGDLTAT
MAB_4151c|M.abscessus_ATCC_199 AIRTTTVLGEKSLSVTPAGAG--RIT-EIPLGRTTTPYTLNSALSDLGAS
Mb0606|M.bovis_AF2122/97 AIRTDTILGRKNLEIEPRGSEPLKPNGFLPLAQTTTPYQIYDAFVDVTKA
MLBr_02591|M.leprae_Br4923 GIRTDTVLGKKVLEVETRGTQLLRPGDSLPLGQSTTPYQSYDAFFDATKV
.*: :** * :.: . * :*: :: :.* .*: *
Rv1968|M.tuberculosis_H37Rv ISGLHTERLSESLATLAQTFADTPAHFRNAIHGVARLAQTLDERDNQLRS
MSMEG_0348|M.smegmatis_MC2_155 VENLNTDDLSAALDTMAQTFAGTPPDVKIAVAGVARLSETINKRDTELRN
TH_4453|M.thermoresistible__bu IAGLDTAGVSESLATLAETFENTPAEVQAAVRGVTRFSESLGRRDQQLRQ
MMAR_4053|M.marinum_M ISGLNTNQLSDSLRVLADTFSDTPPQLRVAIEGVARFSQTLDERDAQLRG
MUL_3920|M.ulcerans_Agy99 ISGLNTNQLSDSLRVLADTFSDTPPQLRVAIEGVARFSQTLDERDAQLRG
Mflv_0650|M.gilvum_PYR-GCK ISGLDTGQLSASLAVLSQTLQDTPDDLRFAVAGIARFSETLNQRDAQLRD
Mvan_0515|M.vanbaalenii_PYR-1 ISGLDTGQLSASLAVLSQTLQDTPDDLRFAVAGIARFSETLNQRDAQLRD
MAV_2534|M.avium_104 ISGLNTDQLSKSLAVLANTFTDTPPDLKAAVQGVARFSQTLDERDGQLRT
MAB_4151c|M.abscessus_ATCC_199 AGGIDKAQLDQSLQVITEAMRDATPQLRGALDGVASLSRTLNARDAALEQ
Mb0606|M.bovis_AF2122/97 ATGWDIDAVKRSLNVLSETFDQTAPHLSAALEGVKAFSDTVGRRGEQIEQ
MLBr_02591|M.leprae_Br4923 ASGWNIDTIKQSLKVVSETIDQTYPHLSAALDGVAKFSDTIGARDKEIKH
. . :. :* .::::: : .. *: *: :: ::. *. :.
Rv1968|M.tuberculosis_H37Rv LLANAAKATGVLANRTDQIVGLVRDTNVVLAQLRTQSAALDRIWANISAV
MSMEG_0348|M.smegmatis_MC2_155 LLANARKATAVLATRTDQVVGLVQDSNALLAELRTQSDALDRVSQDISRA
TH_4453|M.thermoresistible__bu LLENARKATGVLGERSQQIAALVRDSNALLVQLRTESAALDQLSANISAL
MMAR_4053|M.marinum_M LLTNANKATTVLAERSNQVVSLIANTNALLAELTTQRAALDHISGNIAAL
MUL_3920|M.ulcerans_Agy99 LLTNANKATTVLAERSNQVVSLIANTNALLAELTTQRAALDHISGNIAAL
Mflv_0650|M.gilvum_PYR-GCK LLAHAAKATTVLGERSNDIVRLISDTNAVLAQLRTQSAALDEISTSISAV
Mvan_0515|M.vanbaalenii_PYR-1 LLAHAAKATTVLGERSNDIVRLISDTNAVLAQLRTQSAALDEISTSISAV
MAV_2534|M.avium_104 LLSNANKATTVLAERSDEVAKLVRDTNALLRQLRSQSSALEQISNNLAAL
MAB_4151c|M.abscessus_ATCC_199 LLTHAKSVSGILSERAGQVNKLVTDGNQLFAALDERRLAISELINRIQGL
Mb0606|M.bovis_AF2122/97 LLANANRIARVLGDRSEQVNGLLVNAKTLLAAFKQRSQALRILLTNVSEA
MLBr_02591|M.leprae_Br4923 LIAQANQVASVLGDRGAQVDRLLVNTKTLIAAFNERGRAVDALLGNVAAF
*: :* : :*. * :: *: : : :: : . *: : :
Rv1968|M.tuberculosis_H37Rv AEQLRGFIAENRQQLRPALDKLNGVLAIVENRKERVRQAIPLINTYVMSL
MSMEG_0348|M.smegmatis_MC2_155 ATQLRGFMADNRQQLRPMLDKLNGVLTIVDNRKDRLQEAVKLLNKYALSL
TH_4453|M.thermoresistible__bu AQQVSGFISENHDTLSPALEKLNGVLTIVENRKEQVQDALHLAQGYHTRL
MMAR_4053|M.marinum_M GQQLHGLIAENEATMRPALDKLNGVLTILDNRKERLQKAIKLLDDYTMSL
MUL_3920|M.ulcerans_Agy99 GQQLHGLIAENEATMRPALDKLNGVLTILDNRKERLQKAIKLLDDYTMSL
Mflv_0650|M.gilvum_PYR-GCK SRQLAGFIAENKTTLKPALEKLNGVLAILDNRKAQIQESIKGLAAYAMQF
Mvan_0515|M.vanbaalenii_PYR-1 SRQLAGFIAENKTTLKPALEKLNGVLAILDNRKAQIQESIKGLAAYAMQF
MAV_2534|M.avium_104 ARQLKGFIAENRDTLKPALDKLNSVLAIVDNRKENVQKALVGLNKYALGL
MAB_4151c|M.abscessus_ATCC_199 SQQISGFVADNRQEFRPTMEKLSVVLDDLLDRKAHISEALKRLPGYGTAL
Mb0606|M.bovis_AF2122/97 SAQVSGLITDN-PNLNHVLAQLRTVSEELVKRKNELADVAVLLGRYTAAL
MLBr_02591|M.leprae_Br4923 AAQVQRLINDN-PNLNHVLEQLHQLSGILVQHKDDLANTLIQVAAFLPSL
. *: :: :* : : :* : : .:* : . : :
Rv1968|M.tuberculosis_H37Rv GESLSSGPFFKAYVVNLLPGQFVQPFISAAFSDLGLDPATLLPSQ-----
MSMEG_0348|M.smegmatis_MC2_155 GESVGSGPFFKAYIPNLIPGQFSQPFIDAAFSDLGLDPATLLPSQ-----
TH_4453|M.thermoresistible__bu GEAVSSGPFFNSYVANLLPGQFVQPFIDAAFSDLGLDPNVLLPSQ-----
MMAR_4053|M.marinum_M GESVSSGPFFKTYVANLAPGQFVQPFIDAAFSDLGLDPNVLLPSQ-----
MUL_3920|M.ulcerans_Agy99 GESVSSGPFFKTYVANLAPGQFVQPFIDAAFSDLGLDPNVLLPSQ-----
Mflv_0650|M.gilvum_PYR-GCK GETIAAGPFFNAYLANLVPGQFIQPFVDAAFSDLGLDPNVLLPSE-----
Mvan_0515|M.vanbaalenii_PYR-1 GETIAAGPFFNAYLANLVPGQFIQPFVDAAFSDLGLDPNVLLPSE-----
MAV_2534|M.avium_104 GESVSSGPFFKAYVVNLFPGQFVQPFIDAAFSDLGLDPNVLLPSQ-----
MAB_4151c|M.abscessus_ATCC_199 GEVVSSGPGFHVNVYGFPPATLTAVAFDTYF-------------------
Mb0606|M.bovis_AF2122/97 TEAVGSGPFFKAMVVNLLPYQILQPWVDAAFKKRGIDPENFWRSAGLPEF
MLBr_02591|M.leprae_Br4923 NEAIGSGPFFKVVLHNLAPYQILQPWVDAAFKKRGIDPENFWRSAGLPEF
* :.:** *: : .: * : ..: *
Rv1968|M.tuberculosis_H37Rv --LTDPPTGQPGTPPLPMPYPRTGQGGEPRLTLPDAI-------------
MSMEG_0348|M.smegmatis_MC2_155 --LVDPPVGQPGTPALPVPYPRTGQGGEPRLNLPDAI-------------
TH_4453|M.thermoresistible__bu --LNDPQVGQPGTPAAPVPYPRTGQGGGPRLTLPDAI-------------
MMAR_4053|M.marinum_M --RTDPPIGQPGTPPLPLPFPRTGQGGEPHLKLPDAI-------------
MUL_3920|M.ulcerans_Agy99 --RTDPPIGQPGTPPLPLPFPRTGQGGEPHRKLPDAI-------------
Mflv_0650|M.gilvum_PYR-GCK --RTDPQVGQPGTPALPIPYPRTGQGGDPKLTLPDAI-------------
Mvan_0515|M.vanbaalenii_PYR-1 --RTDPQVGQPGTPALPIPYPRTGQGGDPKLTLPDAI-------------
MAV_2534|M.avium_104 --RADPQVGQPATPPLPMPFPRTGQGGEPRMTLPDAI-------------
MAB_4151c|M.abscessus_ATCC_199 ---------QPGKLPASLSDYLNGLIGERQIMRPKSP-------------
Mb0606|M.bovis_AF2122/97 RWPDPNGTRFPNGAPPAAPPVREGTPKHPGPAVPPGTPCSYTPAAG----
MLBr_02591|M.leprae_Br4923 RFPDPNGTRFPNGAPPPAPPVLEGTPENPGPAVPPGSPCSYTPAHPGGNN
* . . . * * .
Rv1968|M.tuberculosis_H37Rv ----------TGNPGDP-------------RYPYRPEPPAPPPGGPPPGP
MSMEG_0348|M.smegmatis_MC2_155 ----------TGNPGDP-------------RYPYREPPPAPAPGGPPPGP
TH_4453|M.thermoresistible__bu ----------TGNPGDP-------------RYPYREPLPAPPPGGPPPGP
MMAR_4053|M.marinum_M ----------TGNPDDP-------------RYPYREPLPAPPPGGPPPGP
MUL_3920|M.ulcerans_Agy99 ----------TGNPDDP-------------RYPYREPLPAPPPGGPPPGP
Mflv_0650|M.gilvum_PYR-GCK ----------TGNPGDP-------------RYPYRESVPAPPPGGPPPGP
Mvan_0515|M.vanbaalenii_PYR-1 ----------TGNPGDP-------------RYPYRESVPAPPPGGPPPGP
MAV_2534|M.avium_104 ----------TGNPGDHPCGSPGAASSGPGCYPYREPLPAPPPGGPPPGP
MAB_4151c|M.abscessus_ATCC_199 --------------------------------------------------
Mb0606|M.bovis_AF2122/97 ------ALPRPDNPLPCAGATVGPFGGPDFPAPLDVQPSPPNPDGPPPTP
MLBr_02591|M.leprae_Br4923 TIGDEMGLPRPWNPLPCAGATAGPYGGPAFPAPIDVQTSPPNPDGLPLLP
Rv1968|M.tuberculosis_H37Rv PAQ-------------------QPGDQP----------------------
MSMEG_0348|M.smegmatis_MC2_155 PAPPVPGLESTPSPTPSPVYVPAPGEPTTPIPAG---EGR----------
TH_4453|M.thermoresistible__bu PAAIPPVPVREPVFVPAPN-EVSAGEPDTPEIDG---ESQ----------
MMAR_4053|M.marinum_M PAPAPPELASIPQPTPSSVLVPAPGEVSAPQTAG---AGR----------
MUL_3920|M.ulcerans_Agy99 PAPAPPELASIPQPTPSSVLVPAPGEVSAPQTAG---AGR----------
Mflv_0650|M.gilvum_PYR-GCK PAPPPPDQQAPQPPTPSPVVVPAPDEVAPGPTDSSIPQGRR---------
Mvan_0515|M.vanbaalenii_PYR-1 PAPPPPDQQAPQPPTPSPVVVPAPDEVAPGPTDSSIPQGRR---------
MAV_2534|M.avium_104 PAQPGQG-AGQSAPLPGP---AQPGEGG---------EGR----------
MAB_4151c|M.abscessus_ATCC_199 --------------------------------------------------
Mb0606|M.bovis_AF2122/97 GILSAGRPGEPAPAVPGIPMPLPPNAPPGARTQPLEP-------------
MLBr_02591|M.leprae_Br4923 GIAIAGRPGDPAPNVPGTPVPLPPNAPPGARTEQLAPAAPAQDSSAPHEP
Rv1968|M.tuberculosis_H37Rv -------------------------
MSMEG_0348|M.smegmatis_MC2_155 -------------------------
TH_4453|M.thermoresistible__bu -------------------------
MMAR_4053|M.marinum_M -------------------------
MUL_3920|M.ulcerans_Agy99 -------------------------
Mflv_0650|M.gilvum_PYR-GCK -------------------------
Mvan_0515|M.vanbaalenii_PYR-1 -------------------------
MAV_2534|M.avium_104 -------------------------
MAB_4151c|M.abscessus_ATCC_199 -------------------------
Mb0606|M.bovis_AF2122/97 ---------FPDGTGGSNQ------
MLBr_02591|M.leprae_Br4923 REQLSAPLINPGGTGGSGGAGGSRN