For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
aa seq not available
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. thermoresistible (build 8) | TH_4242 | - | - | 100% (487) | aldehyde dehydrogenase |
| M. thermoresistible (build 8) | TH_3902 | - | e-104 | 44.72% (483) | PUTATIVE putative 5-carboxymethyl-2-hydroxymuconate |
| M. thermoresistible (build 8) | TH_2504 | - | e-103 | 47.29% (461) | PUTATIVE aldehyde dehydrogenase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0791 | aldA | 1e-108 | 45.64% (482) | aldehyde dehydrogenase NAD dependant AldA |
| M. gilvum PYR-GCK | Mflv_2502 | - | 1e-107 | 47.40% (481) | aldehyde dehydrogenase |
| M. tuberculosis H37Rv | Rv0768 | aldA | 1e-108 | 45.64% (482) | aldehyde dehydrogenase NAD dependent AldA |
| M. leprae Br4923 | MLBr_02573 | gabD1 | 1e-52 | 31.97% (463) | succinic semialdehyde dehydrogenase |
| M. abscessus ATCC 19977 | MAB_1218 | - | 6e-99 | 43.24% (481) | aldehyde dehydrogenase AldA |
| M. marinum M | MMAR_4246 | aldA_1 | 0.0 | 66.32% (481) | NAD-dependent aldehyde dehydrogenase, AldA_1 |
| M. avium 104 | MAV_1340 | - | 0.0 | 67.01% (482) | aldehyde dehydrogenase |
| M. smegmatis MC2 155 | MSMEG_4799 | - | 1e-103 | 46.78% (466) | aldehyde dehydrogenase (NAD) family protein |
| M. ulcerans Agy99 | MUL_0939 | aldA_1 | 0.0 | 66.11% (481) | NAD-dependent aldehyde dehydrogenase, AldA_1 |
| M. vanbaalenii PYR-1 | Mvan_5157 | - | 1e-103 | 43.27% (483) | aldehyde dehydrogenase |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_4246|M.marinum_M ---------MAERALPESLVDTYQLYIDGRWVEPENGRYDDVSPSTGMVI
MUL_0939|M.ulcerans_Agy99 ---------MAERALPESLVDTYQLYIDGRWVEPENGRYDDVSPSTGMVI
MAV_1340|M.avium_104 ---------MAD---PPALVQTYQLYIDGQWVEPQDGRYDDLSPCTEAVI
TH_4242|M.thermoresistible__bu ---------MTR---SHALVETYGHYINGEWVDPDSGRYEDVDPATGETF
Mb0791|M.bovis_AF2122/97 --------------MALWGDGISALLIDGKLSDGRAGTFPTVNPATEEVL
Rv0768|M.tuberculosis_H37Rv --------------MALWGDGISALLIDGKLSDGRAGTFPTVNPATEEVL
MAB_1218|M.abscessus_ATCC_1997 --------------MTVLSDGDSELFIDGKLLPGGAGRFPTVNPATEEVL
Mvan_5157|M.vanbaalenii_PYR-1 --------------MAILADRESRLLIDGKLVAGSSGTFTTVNPATEETL
Mflv_2502|M.gilvum_PYR-GCK MQETVTIPDATSGTETADRRAARRLLIGGQLVDTER-TFASLNPATGDVL
MSMEG_4799|M.smegmatis_MC2_155 MQETSTI--------AAGQRADRKLLIGGELRETSR-TFPSVNPATAEVL
MLBr_02573|M.leprae_Br4923 ------------------------------------MSIATINPATGETV
:.*.* ..
MMAR_4246|M.marinum_M ATAPDASVSQVGDAVDAARRAFDAGPWPAMSHQERGHCLAQLGAALQDYA
MUL_0939|M.ulcerans_Agy99 ATAPDASVSQVGDAVDAARRAFDAGPWPAMSHQERGHCLAQLGAALQDYA
MAV_1340|M.avium_104 ATAPDASVAQVDDAIAAARRAFDSGPWGRISAEQRARCLNQLGEALTKHA
TH_4242|M.thermoresistible__bu AAAPDASTAQVDRAIAAAREAFDSGRWTGLTPEERAKCLQQLGAALLEHA
Mb0791|M.bovis_AF2122/97 GVAADADAEDMGRAIEAARRAFDSTDWSRNT-ELRVRCVRQLRDAMQQHV
Rv0768|M.tuberculosis_H37Rv GVAADADAEDMGRAIEAARRAFDSTDWSRNT-ELRVRCVRQLRDAMQQHV
MAB_1218|M.abscessus_ATCC_1997 GTAADADSDDMSDAIEAARRAFDDSGWSRDV-ALRVHCIRQLRDGMKTHI
Mvan_5157|M.vanbaalenii_PYR-1 GVAADASAEDMSAAIGAARRSFDETDWATNT-DLRVRCIRQLQQAMRDHV
Mflv_2502|M.gilvum_PYR-GCK GYAPDASVADAEAAVAAARAAFDTGDWATDT-ELRIRCLEQLHAALVEHR
MSMEG_4799|M.smegmatis_MC2_155 GYAPDATVADAEAAVAAARTAFDTTSWSTDT-EFRVHCLEQFHRALLEHR
MLBr_02573|M.leprae_Br4923 KTFTPTTQDEVEDAIARAYARFDN--YRHTTFTQRAKWANATADLLEAEA
. : : *: * ** : * : :
MMAR_4246|M.marinum_M DAYFALSQVEWG-----CTANERRLQIDASASAARRAGHLAGTLGDQPIQ
MUL_0939|M.ulcerans_Agy99 DAYFTLSQVEWG-----CTANERRLQIDASASAARRAGHLASTLGDQPIQ
MAV_1340|M.avium_104 DDFFALSQTEWG-----CIGNERIMQIDGAGFMSMHAAQLATQLVDQEVA
TH_4242|M.thermoresistible__bu DDFFALAQLEWG-----CSANERMFHVEGPAVMTTHAGELALEPVEQPID
Mb0791|M.bovis_AF2122/97 EELRELTISEVGAPRMLTASAQLEGPVGDLSFAADTAESYPWKQDLGEAS
Rv0768|M.tuberculosis_H37Rv EELRELTISEVGAPRMLTASAQLEGPVGDLSFAADTAESYPWKQDLGEAS
MAB_1218|M.abscessus_ATCC_1997 EELRELTIAEVGAPRMLTAGAQLEGPVDDLQFAADTAESFDWTSDLGVAS
Mvan_5157|M.vanbaalenii_PYR-1 EELRELTIAEVGAPRMLTSAAQLEGPVEDLSFCADTAESYAWTTDLGIAS
Mflv_2502|M.gilvum_PYR-GCK DELAALTIAEVGATPALCQGAQLDQPIEIVRYYADLLKTYPLTEDLGNIE
MSMEG_4799|M.smegmatis_MC2_155 DELAALTTAEVGATAALCAGAQLDQPIDIVRYYAELLATYPLTEDLGNIE
MLBr_02573|M.leprae_Br4923 NQSAALMTLEMG-KTLQSAKDEAMKCAKGFRYYAEKAETLLADEPAEAAA
: * * * : :
MMAR_4246|M.marinum_M SASG--AAVLCHEPLGVVSILTPWNFPHSLNVMKLSRALAGGNTVVLKPS
MUL_0939|M.ulcerans_Agy99 SASG--AAVLCHEPLGVVSILTPWNFPHSLNVMKLSRALAGGNTVVLKPS
MAV_1340|M.avium_104 GISAG-TTLLRHVPLGVVAVLTPWNFPHCLNVMKLNHALAAGNTVVLKPS
TH_4242|M.thermoresistible__bu AWGAGGTTLLRYEPLGVVSVLTPWNFPHTLNAMKIGSALAAGNTVVLKPS
Mb0791|M.bovis_AF2122/97 PLGIATRRTLAREAVGVVGAITPWNFPHQINLAKLGPALAAGNTVVLKPA
Rv0768|M.tuberculosis_H37Rv PLGIATRRTLAREAVGVVGAITPWNFPHQINLAKLGPALAAGNTVVLKPA
MAB_1218|M.abscessus_ATCC_1997 PMGIKTRRTLAREAVGVVGAVTPWNFPHQINLAKVGPALAAGNTLVLKPA
Mvan_5157|M.vanbaalenii_PYR-1 PMGIKTHRTIAREAVGVVGAITPWNFPHQINLAKIGPALAAGNTLVLKPA
Mflv_2502|M.gilvum_PYR-GCK SRGMQHHRWVEKEAGGVVAAIIAYNYPNQLALAKLAPALAAGCTVVLKSA
MSMEG_4799|M.smegmatis_MC2_155 SRGMQHHRWVEKEAAGVVAAIIAYNYPNQLALAKLAPALAAGCTVVLKAA
MLBr_02573|M.leprae_Br4923 VGAS--KALARYQPLGVVLAVMPWNFPLWQTVRFAAPALMAGNVGLLKHA
. . *** : .:*:* ** .* . :** :
MMAR_4246|M.marinum_M PLTPLAGLALARIIHEHTDIPPGVVNVVTPGGIEASKVLAVDPRIDMVSF
MUL_0939|M.ulcerans_Agy99 PLTPLAGLALARIIHEHTDIPPGVVNVVTPGGIEASKVLTVDPRIDMVSF
MAV_1340|M.avium_104 PLTPLAGLALARLIDEHTDIPPGVVNVVTPSGVEAAKLLTTDPRIDMVSF
TH_4242|M.thermoresistible__bu PLTPLAGFALARMIDEHTDIPPGVVNVVTPSGLDGSKMLTTDPRIDMVSF
Mb0791|M.bovis_AF2122/97 PDTPWCAAALGEIIVEHTDFPPGVVNIVTSSSHALGALLAKDPRVDMISF
Rv0768|M.tuberculosis_H37Rv PDTPWCAAALGEIIVEHTDFPPGVVNIVTSSSHALGALLAKDPRVDMISF
MAB_1218|M.abscessus_ATCC_1997 PDTPWCAAVLGRIIAEHTDFPPGVVNIVTSSDHRIGAQLSTDPRVDMVSF
Mvan_5157|M.vanbaalenii_PYR-1 PDTPWAAAVLGELIAEHTDFPAGVINIVTSSDHGVGALLSKDPRVDMVSF
Mflv_2502|M.gilvum_PYR-GCK PDTPLITLALGELIAEHTDIPPGVVNVLSGADPQVGAALTTSPDVDMVTF
MSMEG_4799|M.smegmatis_MC2_155 PDTPLITLALGELIAHHTDIPPGVVNVISGADPEVGAVLTTSPDVDMVTF
MLBr_02573|M.leprae_Br4923 SNVPQCALYLADVIARG-GFPEDCFQTLLISANGVEAILR-DPRVAAATL
. .* *. :* . .:* . .: : . * .* : ::
MMAR_4246|M.marinum_M TGSSAVGREVMAAAAGTMKRVLLECGGKSASIVLDD-AECSDELLARMLF
MUL_0939|M.ulcerans_Agy99 TGSSAVGCEVMAAAAGTMKRVLLECGGKSASIVLDD-AECSDELLARMLF
MAV_1340|M.avium_104 TGSSAVGRQVMSAAGDTIKRILLELGGKSASIVLDD-ANVTDEMLEQMLF
TH_4242|M.thermoresistible__bu TGSSAVGREVMAGAAGGMKRILLECGGKSASIVLDD-LEVTDELLETILF
Mb0791|M.bovis_AF2122/97 TGSTATGRAVMADAAATIKKVFLELGGKSAFVVLDD---ADLAAASAVSA
Rv0768|M.tuberculosis_H37Rv TGSTATGRAVMADAAATIKKVFLELGGKSAFVVLDD---ADLAAASAVSA
MAB_1218|M.abscessus_ATCC_1997 TGSTATGRAVMTDAAATVKKVFLELGGKSAFIVLDDLDEAALGSACSVAA
Mvan_5157|M.vanbaalenii_PYR-1 TGSTNTGRAVMADGAATLKKVFLELGGKSAFLVIDD---ADLAGACSMAA
Mflv_2502|M.gilvum_PYR-GCK TGSTPTGRAIMAAASGTLKKVFLELGGKSAAIVLDD---ADFSTAALFSA
MSMEG_4799|M.smegmatis_MC2_155 TGSTPTGRRIMAAASETLKKVFLELGGKSAAIILDD---ADFNTAALFSA
MLBr_02573|M.leprae_Br4923 TGSEPAGQAVGAIAGNEIKPTVLELGGSDPFIVMPS---ADLDAAVATAV
*** .* : : .. :* .** **... ::: .
MMAR_4246|M.marinum_M ESCLLHAGQACILHSRLLLPEAMHDEIVDRLVALARAVRVGDPADPDVQM
MUL_0939|M.ulcerans_Agy99 ESCLLHAGQACILHSRLLLPEAMHDEIVDRLVALARAVRVGDPADPDVQM
MAV_1340|M.avium_104 QSCSLHAGQACILHSRLLLPDSLHDDVVDRLAALARDVKVGDPTDPDVQM
TH_4242|M.thermoresistible__bu ECLTMHAGQACILNSRLVVPEAMHDDVVARLGELARKVVVGNPVDPAVQM
Mb0791|M.bovis_AF2122/97 FSACMHAGQGCAITTRLVVPRARYEEAVAIAAATMSSIRPGDPNDPGTVC
Rv0768|M.tuberculosis_H37Rv FSACMHAGQGCAITTRLVVPRARYEEAVAIAAATMSSIRPGDPNDPGTVC
MAB_1218|M.abscessus_ATCC_1997 FTAAMHAGQGCAITTRLVVPRERYDDAVAAAAATMGSLKPGDPAKPGTIC
Mvan_5157|M.vanbaalenii_PYR-1 FTASMHAGQGCAITTRLVVPRDRYDEAVEAAAATMGGLKAGDPTKPGTVC
Mflv_2502|M.gilvum_PYR-GCK FSMVTHAGQGCALTSRLLVPRKHKDEIVELVKNNFGLVRLGDPADPSTYM
MSMEG_4799|M.smegmatis_MC2_155 FSMVTHAGQGCALTSRLLVPAAHKDEIVELIKNNFAMVRYGDPADPKTYM
MLBr_02573|M.leprae_Br4923 TGRVQNNGQSCIAAKRFIAHADIYDEFVEKFVARMETLRVGDPTDPDTDV
: **.* .*:: :: * : *:* .* .
MMAR_4246|M.marinum_M GPLISAAQRSRVEDQVARALRDGATLAAGGRRPATPEAGFYYEPTILTGV
MUL_0939|M.ulcerans_Agy99 GPLISAAQRSRVEDQVARALRDGATLAAGGRRPATPEAGFYYEPTILTGV
MAV_1340|M.avium_104 GPLISAAQRDRVEAHIAGARSDGATLVTGGGRPAGLDVGYYVEPTILSGV
TH_4242|M.thermoresistible__bu GPLISRAHLERVEGFVERAVADGATVVAGGSRPAHLDRGFFYEPTILTDV
Mb0791|M.bovis_AF2122/97 GPLISARQRDRVQGYLDLAVAEGGRFACGGARPADREVGFYIEPTVIAGL
Rv0768|M.tuberculosis_H37Rv GPLISARQRDRVQGYLDLAVAEGGRFACGGARPADREVGFYIEPTVIAGL
MAB_1218|M.abscessus_ATCC_1997 GPVISARQRDRVQSYLDLAVAEGGSFACGGGRPEGKDRGFFIEPTVVAGL
Mvan_5157|M.vanbaalenii_PYR-1 GPLISERQRERVQGYLDSAIAEGGRFACGGGRPADRDTGFFIDPTVIAGL
Mflv_2502|M.gilvum_PYR-GCK GPLISEKQRDKVDGMVKRAVEAGATLVTGGEK---VDPGYFYTPTLLADV
MSMEG_4799|M.smegmatis_MC2_155 GPLISEKQRDKVDGMVKRAVAAGATLVTGGEK---VDPGYFYTPTLLADV
MLBr_02573|M.leprae_Br4923 GPLATESGRAQVEQQVDAAAAAGAVIRCGGKRPD--RPGWFYPPTVITDI
**: : :*: : * *. . ** : *:: **:::.:
MMAR_4246|M.marinum_M TPDAHIAQNEVFGPVLSVLRYRDDDDAVAIANNSQYGLSGAVWGGDADRA
MUL_0939|M.ulcerans_Agy99 TPDAHIAQNEVFGPVLSVLRYRDDDDAVAIANNSQYGLSGAVWGGDADRA
MAV_1340|M.avium_104 EPNSTVAQEEVFGPVLSVLRYRDDDDAVAIANNSRYGLSGAVWGDDVDRA
TH_4242|M.thermoresistible__bu APDDFIAQEEVFGPVLTVLRCRDDDEAVDIANNSRYGLGGAVYAADVDRA
Mb0791|M.bovis_AF2122/97 TNDARVAREEIFGPVLTVIAHDGDDDAVRIANDSPYGLSGTVYGADPQRA
Rv0768|M.tuberculosis_H37Rv TNDARVAREEIFGPVLTVIAHDGDDDAVRIANDSPYGLSGTVYGADPQRA
MAB_1218|M.abscessus_ATCC_1997 TNAARVAREEIFGPVLVVIAHDGDEDAVRIANDSPYGLSGTVFGDDDERS
Mvan_5157|M.vanbaalenii_PYR-1 DNNAKVAREEIFGPVLTVIAHDGDDDAVRIANDSPYGLSGTVFSADPERA
Mflv_2502|M.gilvum_PYR-GCK DPDSEIAQEEVFGPVLTVIAYEDDDDAVRIANNSIYGLSGAVFGSQ-DRA
MSMEG_4799|M.smegmatis_MC2_155 DPDSEIAQEEVFGPVLAVISYTDDDDAVRIANNSIYGLSGAVFGSQ-ERA
MLBr_02573|M.leprae_Br4923 TKDMALYTDEVFGPVASVYCATNIDDAIEIANATPFGLGSNAWTQNESEQ
: :*:**** * . ::*: *** : :**.. .: : ..
MMAR_4246|M.marinum_M VRVARRIRTGQIAVNG--FGPGDAPFGGFKQSGLGREGGGIAGLHQYMEP
MUL_0939|M.ulcerans_Agy99 VRVARRIRTGQIAVNG--FGPGDAPFGGFKQSGLGREGGGIAGLHQYMEP
MAV_1340|M.avium_104 VGVARRIRTGQIAVNG--ISPAGAPFGGFRLSGLGREGGGIGGLHQYMEP
TH_4242|M.thermoresistible__bu LGVARRIRSGQVSING--CIAGDAPFGGFGQSGIGREGG-LLGLRSYMEP
Mb0791|M.bovis_AF2122/97 ARIASRLRVGTVNVNGGVWYCADAPFGGYKQSGIGREMG-LLGFEEYLEA
Rv0768|M.tuberculosis_H37Rv ARIASRLRVGTVNVNGGVWYCADAPFGGYKQSGIGREMG-LLGFEEYLEA
MAB_1218|M.abscessus_ATCC_1997 ARVASRLRVGTVNVNGGVWYSADAPFGGYKQSGNGREMG-VAGFEEYLET
Mvan_5157|M.vanbaalenii_PYR-1 AGIAARMRVGTVNVNGGVWYSADMPFGGYKQSGIGREMG-LAGFEEYLEI
Mflv_2502|M.gilvum_PYR-GCK LGVARRIRTGTFSINGGNYFSPDSPFGGYKQSGIGREMG-RAGLEEFLES
MSMEG_4799|M.smegmatis_MC2_155 LAVSRRIRTGTFSINGGNYFSPDSPFGGYKQSGIGREMG-TAGLEEFLES
MLBr_02573|M.leprae_Br4923 RHFIDNIVAGQVFINGMTVSYPELPFGGIKRSGYGRELS-THGIREFCNI
. .: * . :** **** ** *** . *:..: :
MMAR_4246|M.marinum_M KAIGMPG-
MUL_0939|M.ulcerans_Agy99 KAIGMPG-
MAV_1340|M.avium_104 MAIGVPA-
TH_4242|M.thermoresistible__bu KAIGVPA-
Mb0791|M.bovis_AF2122/97 KLIATAAN
Rv0768|M.tuberculosis_H37Rv KLIATAAN
MAB_1218|M.abscessus_ATCC_1997 KVIATAVK
Mvan_5157|M.vanbaalenii_PYR-1 KAIATAAN
Mflv_2502|M.gilvum_PYR-GCK KTFATVAG
MSMEG_4799|M.smegmatis_MC2_155 KTFATVVA
MLBr_02573|M.leprae_Br4923 KTVWIA--
.