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aa seq not available
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. thermoresistible (build 8) | TH_3902 | - | - | 100% (501) | putative 5-carboxymethyl-2-hydroxymuconate Delta-isomerase |
| M. thermoresistible (build 8) | TH_3080 | - | e-112 | 45.95% (481) | PUTATIVE aldehyde dehydrogenase |
| M. thermoresistible (build 8) | TH_3591 | - | e-106 | 43.62% (486) | PUTATIVE putative Betaine-aldehyde dehydrogenase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0791 | aldA | 1e-104 | 44.35% (478) | aldehyde dehydrogenase NAD dependant AldA |
| M. gilvum PYR-GCK | Mflv_0428 | - | 1e-116 | 46.90% (484) | betaine-aldehyde dehydrogenase |
| M. tuberculosis H37Rv | Rv0223c | - | 1e-120 | 47.64% (487) | aldehyde dehydrogenase |
| M. leprae Br4923 | MLBr_02573 | gabD1 | 5e-58 | 32.18% (463) | succinic semialdehyde dehydrogenase |
| M. abscessus ATCC 19977 | MAB_4484 | - | 1e-118 | 46.30% (486) | aldehyde dehydrogenase |
| M. marinum M | MMAR_0472 | - | 1e-115 | 45.76% (483) | aldehyde dehydrogenase |
| M. avium 104 | MAV_4946 | - | 1e-115 | 46.17% (483) | aldehyde dehydrogenase family protein |
| M. smegmatis MC2 155 | MSMEG_0309 | - | 1e-114 | 45.36% (496) | aldehyde dehydrogenase family protein |
| M. ulcerans Agy99 | MUL_1122 | - | 1e-113 | 44.93% (483) | aldehyde dehydrogenase |
| M. vanbaalenii PYR-1 | Mvan_0240 | - | 1e-116 | 46.69% (484) | betaine-aldehyde dehydrogenase |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_0472|M.marinum_M -----------MGEKTEYDKLFIGGKWTEPSTSEVIEVHCPATGEYVGKV
MUL_1122|M.ulcerans_Agy99 -----------MGEKTEYDKLFIGGRWTEPSTSEVIEVHCPATGEYVGKV
MAV_4946|M.avium_104 ------MSDIQTQAKTEYDKLFIGGKWTEPSTSEVIEVHCPATGEYVGKV
Rv0223c|M.tuberculosis_H37Rv ----------MSDSATEYDKLFIGGKWTKPSTSDVIEVRCPATGEYVGKV
MAB_4484|M.abscessus_ATCC_1997 --------------MTNYDKLFIGGVWTEPATDQVIEVISPATGQKVGQC
Mflv_0428|M.gilvum_PYR-GCK ---MTQS----TAFRTEWDKLFIGGKWVEPASSEVIEVRSPATGDVVGKV
Mvan_0240|M.vanbaalenii_PYR-1 ---MTQS----TTFRTEWDKLFIGGKWVEPATSDVIEVHSPATGELVGKV
MSMEG_0309|M.smegmatis_MC2_155 MTAMTQTAPAATAATTNWDKLFIGGQWVEPSSSEIIEVFSPATGEKVGQA
TH_3902|M.thermoresistible__bu --LRANRFQPKDNTVTWKYDLYIDGKWDTGTSGRALTVVNPATEETIGTV
Mb0791|M.bovis_AF2122/97 ----------MALWGDGISALLIDGKLSDGRAG-TFPTVNPATEEVLGVA
MLBr_02573|M.leprae_Br4923 ---------------------------------MSIATINPATGETVKTF
: . *** : :
MMAR_0472|M.marinum_M PLAAAADVDAAVAAARAAFDNGPWPSTPPKERATVIANALKLLEERKDHF
MUL_1122|M.ulcerans_Agy99 PLAAAADVDAAVAAARAAFDNGPWPSTPPKERATVIANALKLLEERKDHF
MAV_4946|M.avium_104 PLAAAADVDAAVAAARAAFDNGPWPTTPPKERAAVIANALKVMEERKDLF
Rv0223c|M.tuberculosis_H37Rv PMAAAADVDAAVAAARAAFDNGPWPSTPPHERAAVIAAAVKMLAERKDLF
MAB_4484|M.abscessus_ATCC_1997 PLASPADVDAAVSAARRAFDNGPWPRLTPHERQAVLQKAVSLLESRKDEI
Mflv_0428|M.gilvum_PYR-GCK PLASAADVDAACAAAREAFDNGPWPQMSPTERAEVLGRAVKLMEERADEL
Mvan_0240|M.vanbaalenii_PYR-1 PLASAADVDAACAAAREAFDNGPWPHMSPAERGEILGRAVKIMEERADEL
MSMEG_0309|M.smegmatis_MC2_155 PLATKADVDAACAAARKAFDEGPWPRMTPQEREAVLAKATALIEESADEF
TH_3902|M.thermoresistible__bu PDASLDDIRRAIAAARTAFDEGPWPCMTPLERAAVIRRIAEVLQRRRSEL
Mb0791|M.bovis_AF2122/97 ADADAEDMGRAIEAARRAFDSTDWSRNT-ELRVRCVRQLRDAMQQHVEEL
MLBr_02573|M.leprae_Br4923 TPTTQDEVEDAIARAYARFDN--YRHTTFTQRAKWANATADLLEAEANQS
. : :: * * **. : . * : .
MMAR_0472|M.marinum_M AKLLADETGQPPMTVETMHWMGSIGALNFFAGPAVDQVRWKEIRNGSY--
MUL_1122|M.ulcerans_Agy99 AKLFADETGQPPMTVETMHWMGSIGALNFFAGPAVDQVRWKEIRNGSY--
MAV_4946|M.avium_104 TGLLAAETGQPPTSVETMHWMSSIGALNFFAGPAVDQVKWKEVRTGGY--
Rv0223c|M.tuberculosis_H37Rv TKLLAAETGQPPTIIETMHWMGSMGAMNYFAG-AADKVTWTETRTGSY--
MAB_4484|M.abscessus_ATCC_1997 CKAIADETGAPPMVIETLQWMGGFGAIQYYAN-AADAVKWKELRNGAY--
Mflv_0428|M.gilvum_PYR-GCK KFLLAAETGQPPTIVDMMQYGAAMSSFQFYAG-AADKFTWQDIRDGVY--
Mvan_0240|M.vanbaalenii_PYR-1 KFLLAAETGQPPTIVDMMQYGAAMSSFQFYAG-AADKFTWQDIRDGVY--
MSMEG_0309|M.smegmatis_MC2_155 KTLLKLETGQPQTIVDMMQYGAAMSTLQFYAS-AADKFAWKDIRDGIY--
TH_3902|M.thermoresistible__bu VDLVRAETGSPQWIVEMLQVGVPLRVCADVADRVLPQFRFVEPMLPSFDL
Mb0791|M.bovis_AF2122/97 RELTISEVGAPRMLTASAQLEGPVGDLSFAADTAESYPWKQDLGEASPLG
MLBr_02573|M.leprae_Br4923 AALMTLEMGKTLQSAKDEAMKCAKG-FRYYAEKAETLLADEPAEAAAVG-
* * . * .
MMAR_0472|M.marinum_M --GQTIVHREPIGVVGAIVAWNVPLFLAINKLGPALLAGCTVVLKPAAET
MUL_1122|M.ulcerans_Agy99 --GQTIVHREPIGVVGAIVAWNVPLFLAINKLGPAPLAGCTVVLKPAAET
MAV_4946|M.avium_104 --GQSIVHREPIGVVGAIVAWNVPLFLAVNKLGPALLAGCTVVLKPAAET
Rv0223c|M.tuberculosis_H37Rv --GQSIVSREPVGVVGAIVAWNVPLFLAVNKIAPALLAGCTIVLKPAAET
MAB_4484|M.abscessus_ATCC_1997 --GQTLVTREPAGVVAAIAAWNVPLFLALNKIGPAFLAGCAVVLKPAAET
Mflv_0428|M.gilvum_PYR-GCK --GQTLVVREPVGVVGAVTAWNVPFFLAANKLGPALLAGCTVVLKPAAET
Mvan_0240|M.vanbaalenii_PYR-1 --GQTLVVREPVGVVGAVTAWNVPFFLAANKLGPALLAGCTVVLKPAAET
MSMEG_0309|M.smegmatis_MC2_155 --GQTLVLKEPVGVVGAVVAWNVPFFLAANKLGPALLAGCTIVLKPAAET
TH_3902|M.thermoresistible__bu RPGQGIISKEPIGVAALITPFNFPLFLNVMKLAPALAAGCTVVLKPSPLT
Mb0791|M.bovis_AF2122/97 IATRRTLAREAVGVVGAITPWNFPHQINLAKLGPALAAGNTVVLKPAPDT
MLBr_02573|M.leprae_Br4923 -ASKALARYQPLGVVLAVMPWNFPLWQTVRFAAPALMAGNVGLLKHASNV
: :. **. : .:*.* .** ** . :** :. .
MMAR_0472|M.marinum_M PLTANALAEVFAEAG-LPEGVLSVVPGG-VETGQALTSNPGVDLFTFTGS
MUL_1122|M.ulcerans_Agy99 PLTANALAEVFAEAG-LPEGVLSVVPGG-VETGQALTSNPGVDLFTFTGS
MAV_4946|M.avium_104 PLSANALAEAFAEAG-LPEGVLSVVPGG-IETGQALTSNTDVDIFSFTGS
Rv0223c|M.tuberculosis_H37Rv PLTANALAEVFAEVG-LPEGVLSVVPGG-IETGQALTSNPDIDMFTFTGS
MAB_4484|M.abscessus_ATCC_1997 PLSSFILAEVFAEAG-VPEGVLSVVPGG-AETGRALTNNPDVDVFSFTGS
Mflv_0428|M.gilvum_PYR-GCK PLSVFAMAEMFVEAG-LPEGVLSIVPGG-PETGQALTANPNLDKYTFTGS
Mvan_0240|M.vanbaalenii_PYR-1 PLSVFAMAEMFVEAG-LPEGVLSIVPGG-PETGQALTANPNLDKYTFTGS
MSMEG_0309|M.smegmatis_MC2_155 PLTTNLMAQKFLEAG-LPEGVLSVVPGG-PETGRALTDNPALDKFTFTGS
TH_3902|M.thermoresistible__bu PLEALVLGEVADEVG-LPPGVLNIVTGG-AEESAELTTNPMVDLVSFTGS
Mb0791|M.bovis_AF2122/97 PWCAAALGEIIVEHTDFPPGVVNIVTSSSHALGALLAKDPRVDMISFTGS
MLBr_02573|M.leprae_Br4923 PQCALYLADVIARGG-FPEDCFQTLLIS-ANGVEAILRDPRVAAATLTGS
* :.: . .* . .. : . : :. : ::***
MMAR_0472|M.marinum_M SAVGKEIGRRAAEMLKPCTLELGGKSAAILLEDVDLSTAVPMMVFSGIMN
MUL_1122|M.ulcerans_Agy99 SAVGKEIGRRAAEMLKPCTLELGGKSAAILLEDVDLSTAVPMMVFSGIMN
MAV_4946|M.avium_104 SAVGREIGRRAADMLKPCTLELGGKSAAIVLDDVDLPSALPMLVFSGIMN
Rv0223c|M.tuberculosis_H37Rv SAVGREVGRRAAEMLKPCTLELGGKSAAIILEDVDLAAAIPMMVFSGVMN
MAB_4484|M.abscessus_ATCC_1997 TAVGKEIAEIAAKNLKKVTLELGGKSAAIVLEDADLAAALPMLVFSGLMN
Mflv_0428|M.gilvum_PYR-GCK SGVGKEIAKIAADKLKPCTLELGGKSAAIILEDADLDSTLPMLVFSGLMN
Mvan_0240|M.vanbaalenii_PYR-1 SGVGKEIAKIAADKLKPCTLELGGKSAAIILEDADLDSTLPMLVFSGLMN
MSMEG_0309|M.smegmatis_MC2_155 SAVGKEIGKIAAEKLKPCTLELGGKSAAIILEDADLDSTLPMLLFSGLMN
TH_3902|M.thermoresistible__bu DTVGRQVMNQASATLKKVVLELGGKSANVIFADADLDAAAAHVVGEFTLH
Mb0791|M.bovis_AF2122/97 TATGRAVMADAAATIKKVFLELGGKSAFVVLDDADLAAASAVSAFSACMH
MLBr_02573|M.leprae_Br4923 EPAGQAVGAIAGNEIKPTVLELGGSDPFIVMPSADLDAAVATAVTGRVQN
.*: : *. :* *****... ::: ..** :: . :
MMAR_0472|M.marinum_M TGQACVGQTRILAPRSRYEEIVEAVSAFVQALPVGPPSDPAAQIGSLISE
MUL_1122|M.ulcerans_Agy99 TGQACVGQTRILAPRSRYEEIVEAVSAFVQTLPVGPPSDPAAQIGSLISE
MAV_4946|M.avium_104 SGQACVAQTRILAPRSRYDEIVDAVSTFVQSLPVGLPSDPAAQIGSLISE
Rv0223c|M.tuberculosis_H37Rv AGQGCVNQTRILAPRSRYDEIVAAVTNFVTALPVGPPSDPAAQIGPLISE
MAB_4484|M.abscessus_ATCC_1997 AGQGCVNQTRVLAPRSRYDEVVDGIVGMVSLMGVGLPDDPATQVGPLITE
Mflv_0428|M.gilvum_PYR-GCK SGQACVGQTRILAPRSRYDEVIEKLGEAVRNMAPGLPDNPAAMIGPLISE
Mvan_0240|M.vanbaalenii_PYR-1 SGQACVGQTRILAPRSRYDEVVEKLAAAAAGMAPGLPDNPAAMIGPLISE
MSMEG_0309|M.smegmatis_MC2_155 SGQACVGQTRILAPRSRYDEVVEKVAAGVAAMQVGVPDDPAAMVGPLISE
TH_3902|M.thermoresistible__bu AGQGCSLLTRTLVEESIHDELVDWVNKQLAALKVGDPADPSVMMGPLISE
Mb0791|M.bovis_AF2122/97 AGQGCAITTRLVVPRARYEEAVAIAAATMSSIRPGDPNDPGTVCGPLISA
MLBr_02573|M.leprae_Br4923 NGQSCIAAKRFIAHADIYDEFVEKFVARMETLRVGDPTDPDTDVGPLATE
**.* .* :. ::* : : * * :* . *.* :
MMAR_0472|M.marinum_M KQRARVEGYIAKGIEEGARLVSGGGRPEGLDNGFFVQPTVFADVDNKMTI
MUL_1122|M.ulcerans_Agy99 KQRARVEGYIAKGIEEGARLVSGGGRPESLDNGFFVQPTVFADVDNKMTI
MAV_4946|M.avium_104 KQRARVEGYIAKGIEEGARLVCGGGRPEGLDSGFFVQPTVFADVDNKMTI
Rv0223c|M.tuberculosis_H37Rv KQRTRVEGYIAKGIEEGARLVCGGGRPEGLDNGFFIQPTVFADVDNKMTI
MAB_4484|M.abscessus_ATCC_1997 KQRTRVEGYIAKGIAEGARLAYGGKRPEGLDGGYFVQPTIFADVDNSMTI
Mflv_0428|M.gilvum_PYR-GCK KQRDRVEGYIKKGIEEGARVITGGGRPEGLDSGWFVEPTVFADVDNSMTI
Mvan_0240|M.vanbaalenii_PYR-1 KQRDRVEGYIKKGIEEGARVVTGGGRPEGLDSGWYVQPTVFADVDNSMTI
MSMEG_0309|M.smegmatis_MC2_155 KQRERVEGYIKKGIEEGARLVTGGGRPEGLDSGWFVQPTVFADVDNSMTI
TH_3902|M.thermoresistible__bu AQRNRVEGYIKAGVDEGAEIAFGGGRPSHLERGYFVEPTLFTGVRNEMKI
Mb0791|M.bovis_AF2122/97 RQRDRVQGYLDLAVAEGGRFACGGARPADREVGFYIEPTVIAGLTNDARV
MLBr_02573|M.leprae_Br4923 SGRAQVEQQVDAAAAAGAVIRCGGKRPD--RPGWFYPPTVITDITKDMAL
* :*: : . *. . ** ** *:: **:::.: :. :
MMAR_0472|M.marinum_M AQEEIFGPVLVVIPYDTEEDAIKIANDSVYGLAGSVWTSNVPKGIEISEK
MUL_1122|M.ulcerans_Agy99 AQEEIFGPVLVVIPYDTKEDAIKIANDSVYGLAGSVWTSNVPKGIEISEK
MAV_4946|M.avium_104 AQEEIFGPVLSIIPYDTEEDAIKIANDSVYGLAGSVWTADVQRGIAVSEK
Rv0223c|M.tuberculosis_H37Rv AQEEIFGPVLAIIPYDTEEDAIAIANDSVYGLAGSVWTTDVPKGIKISQQ
MAB_4484|M.abscessus_ATCC_1997 AQEEIFGPVLSIIAYDSVDEAVKIANDSNYGLAGSVWTTDVQKGLEVAAQ
Mflv_0428|M.gilvum_PYR-GCK AQEEIFGPVLSVIPYEDEDDAVRIANDSVYGLAGSVYTTDNDRALKIARR
Mvan_0240|M.vanbaalenii_PYR-1 AQEEIFGPVLAVIPYEDEDDAVRIANDSVYGLAGSVYTTDNDRALKIARR
MSMEG_0309|M.smegmatis_MC2_155 AQEEIFGPVLVVIPFEDEDDAVRIANDSVYGLAGSVYTTDHAKGVEIASK
TH_3902|M.thermoresistible__bu AQEEIFGPVGVVIPFTSEHEAVRLANDSDFGLGGGVWSTDVERALRVAQR
Mb0791|M.bovis_AF2122/97 AREEIFGPVLTVIAHDGDDDAVRIANDSPYGLSGTVYGADPQRAARIASR
MLBr_02573|M.leprae_Br4923 YTDEVFGPVASVYCATNIDDAIEIANATPFGLGSNAWTQNESEQRHFIDN
:*:**** : .:*: :** : :**.. .: : . . .
MMAR_0472|M.marinum_M IRTGTYAIN--WYAFDPCCPFGGYKNSGIGRENGPEGVEHFTQQKSVLMP
MUL_1122|M.ulcerans_Agy99 IRTGTYAIN--WYAFDPCCPFGGYKNSGIGRENGPEGVEHFTQQKSVLMP
MAV_4946|M.avium_104 IRTGTYAIN--WYAFDPCCPFGGYKNSGIGRENGPEGVEHFTQQKSVLMP
Rv0223c|M.tuberculosis_H37Rv IRTGTYGIN--WYAFDPGSPFGGYKNSGIGRENGPEGVEHFTQQKSVLLP
MAB_4484|M.abscessus_ATCC_1997 IRTGTYGIN--WYAFDPSCPFGGYKQSGIGRENGPEGIEEYCELKSVLLP
Mflv_0428|M.gilvum_PYR-GCK IRTGTYAVN--MYAFDPCAPFGGYKNSGIGRENGWEGIEAYCEQKSILLP
Mvan_0240|M.vanbaalenii_PYR-1 IRTGTYAVN--MYAFDPCAPFGGFKNSGIGRENGWEGIEAYCEPKSILLP
MSMEG_0309|M.smegmatis_MC2_155 VRTGTYGIN--MYAFDPGAPFGGYKNSGIGRECGPEGIAGYCESKSVLLP
TH_3902|M.thermoresistible__bu IRTGMVAINGGGGSMGKTGPFGGFKASGLGREWGEWGLDEFLEMKQIIWP
Mb0791|M.bovis_AF2122/97 LRVGTVNVNG-GVWYCADAPFGGYKQSGIGREMGLLGFEEYLEAKLIATA
MLBr_02573|M.leprae_Br4923 IVAGQVFING-MTVSYPELPFGGIKRSGYGRELSTHGIREFCNIKTVWIA
: .* :* **** * ** *** . *. : : * : .
MMAR_0472|M.marinum_M MGYTLES-
MUL_1122|M.ulcerans_Agy99 MGYTLES-
MAV_4946|M.avium_104 MGYTLEG-
Rv0223c|M.tuberculosis_H37Rv MGYTVA--
MAB_4484|M.abscessus_ATCC_1997 MGYTLESI
Mflv_0428|M.gilvum_PYR-GCK FGYTPPAS
Mvan_0240|M.vanbaalenii_PYR-1 FGYTPAT-
MSMEG_0309|M.smegmatis_MC2_155 FGYTPE--
TH_3902|M.thermoresistible__bu IAGG----
Mb0791|M.bovis_AF2122/97 AN------
MLBr_02573|M.leprae_Br4923 --------