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aa seq not available
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. thermoresistible (build 8) | TH_4167 | - | - | 100% (674) | acetoin:2,6-dichlorophenolindophenol oxidoreductase beta subunit |
| M. thermoresistible (build 8) | TH_0717 | pdhB | 2e-64 | 45.06% (324) | PROBABLE PYRUVATE DEHYDROGENASE E1 COMPONENT (BETA SUBUNIT) |
| M. thermoresistible (build 8) | TH_0718 | pdhA | 2e-39 | 36.54% (312) | PROBABLE PYRUVATE DEHYDROGENASE E1 COMPONENT (ALPHA SUBUNIT) |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2524c | pdhB | 3e-61 | 41.46% (328) | pyruvate dehydrogenase E1 component beta subunit PdhB |
| M. gilvum PYR-GCK | Mflv_3923 | - | 2e-06 | 25.20% (254) | 1-deoxy-D-xylulose-5-phosphate synthase |
| M. tuberculosis H37Rv | Rv2496c | pdhB | 5e-62 | 41.77% (328) | pyruvate dehydrogenase E1 component beta subunit PdhB |
| M. leprae Br4923 | MLBr_01038 | dxs | 8e-07 | 27.04% (233) | 1-deoxy-D-xylulose-5-phosphate synthase |
| M. abscessus ATCC 19977 | MAB_0896c | - | 5e-64 | 42.94% (326) | putative pyruvate dehydrogenase E1 component, beta subunit |
| M. marinum M | MMAR_3843 | pdhB | 2e-64 | 41.83% (349) | pyruvate dehydrogenase E1 component (beta subunit) PdhB |
| M. avium 104 | MAV_2948 | - | 1e-92 | 53.21% (327) | acetoin:2,6-dichlorophenolindophenol oxidoreductase beta |
| M. smegmatis MC2 155 | MSMEG_4711 | - | 5e-67 | 44.71% (331) | pyruvate dehydrogenase E1 component subunit beta |
| M. ulcerans Agy99 | MUL_3774 | pdhB | 5e-65 | 42.12% (349) | pyruvate dehydrogenase E1 component (beta subunit) PdhB |
| M. vanbaalenii PYR-1 | Mvan_4085 | - | 6e-64 | 43.11% (334) | transketolase, central region |
CLUSTAL 2.0.9 multiple sequence alignment
TH_4167|M.thermoresistible__bu MATQLDVEAPTSANDRAIALYRLMSKVHHADARVRKGLSSGEIAMSYWPV
MAV_2948|M.avium_104 --------------------------------------------------
MSMEG_4711|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_4085|M.vanbaalenii_PYR-1 --------------------------------------------------
Mb2524c|M.bovis_AF2122/97 --------------------------------------------------
Rv2496c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_3843|M.marinum_M --------------------------------------------------
MUL_3774|M.ulcerans_Agy99 --------------------------------------------------
MAB_0896c|M.abscessus_ATCC_199 --------------------------------------------------
Mflv_3923|M.gilvum_PYR-GCK --------------------------------------------------
MLBr_01038|M.leprae_Br4923 --------------------------------------------------
TH_4167|M.thermoresistible__bu TGQEAMSAGAALALSDGDQLVSTYRGLGDVVAKGIDLAGYFGEILGRRTG
MAV_2948|M.avium_104 --------------------------------------------------
MSMEG_4711|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_4085|M.vanbaalenii_PYR-1 --------------------------------------------------
Mb2524c|M.bovis_AF2122/97 --------------------------------------------------
Rv2496c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_3843|M.marinum_M --------------------------------------------------
MUL_3774|M.ulcerans_Agy99 --------------------------------------------------
MAB_0896c|M.abscessus_ATCC_199 --------------------------------------------------
Mflv_3923|M.gilvum_PYR-GCK --------MLEQIRGPADLQHLSRAQMEDLAREIRDFLIHKVAATGGHLG
MLBr_01038|M.leprae_Br4923 --------MLEQIRRPADLQHLSQQQLRDLAAEIRELLVHKVAATGGHLG
TH_4167|M.thermoresistible__bu LSRGKAGAMGISDPDHGIAWTTGIVGAGPLFANGIALAASIRGTGQVVLV
MAV_2948|M.avium_104 --------------------------------------------------
MSMEG_4711|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_4085|M.vanbaalenii_PYR-1 --------------------------------------------------
Mb2524c|M.bovis_AF2122/97 --------------------------------------------------
Rv2496c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_3843|M.marinum_M --------------------------------------------------
MUL_3774|M.ulcerans_Agy99 --------------------------------------------------
MAB_0896c|M.abscessus_ATCC_199 --------------------------------------------------
Mflv_3923|M.gilvum_PYR-GCK PNLGVVELTLALHRVFDSPHDPILFDTGHQAYVHKMLTGRSRDFDTLRKK
MLBr_01038|M.leprae_Br4923 PNLGVVELTLALHRVFDSPHDPIIFDTGHQAYVHKMLTGRCQDFDSLRKK
TH_4167|M.thermoresistible__bu SFGDGATSIGYVHEAMNMAALWNLPVVFFCQNNAWAECTAMERYTRTARL
MAV_2948|M.avium_104 --------------------------------------------------
MSMEG_4711|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_4085|M.vanbaalenii_PYR-1 --------------------------------------------------
Mb2524c|M.bovis_AF2122/97 --------------------------------------------------
Rv2496c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_3843|M.marinum_M --------------------------------------------------
MUL_3774|M.ulcerans_Agy99 --------------------------------------------------
MAB_0896c|M.abscessus_ATCC_199 --------------------------------------------------
Mflv_3923|M.gilvum_PYR-GCK DGLSGYPSRSESEHDWVESSHASSALSYADGLAKAFELNGHRNRHVVAVV
MLBr_01038|M.leprae_Br4923 AGLSGYPSRAESEHDWVESSHASTALSYADGLAKAFELAGNRNRHVVAVV
TH_4167|M.thermoresistible__bu SDRAQGYGMPGVTVDGTDPRAVHDAVAEAVTRARSGGGPTFVEALAYRLQ
MAV_2948|M.avium_104 --------------------------------------------------
MSMEG_4711|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_4085|M.vanbaalenii_PYR-1 --------------------------------------------------
Mb2524c|M.bovis_AF2122/97 --------------------------------------------------
Rv2496c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_3843|M.marinum_M --------------------------------------------------
MUL_3774|M.ulcerans_Agy99 --------------------------------------------------
MAB_0896c|M.abscessus_ATCC_199 --------------------------------------------------
Mflv_3923|M.gilvum_PYR-GCK GDGALTGGMCWEALNNIAASRRPVVIVVNDNGRSYAPTIGGFAEHLAGLR
MLBr_01038|M.leprae_Br4923 GDGALTGGMCWEALNNIAATPRPVVIVVNDNGRSYAPTIGGVADHLATLR
TH_4167|M.thermoresistible__bu GHYFGDTMAYADPDELAAKRADPPFDRYRRRLIDEGIATAATLDQIDAEL
MAV_2948|M.avium_104 --------------------------------------------------
MSMEG_4711|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_4085|M.vanbaalenii_PYR-1 --------------------------------------------------
Mb2524c|M.bovis_AF2122/97 --------------------------------------------------
Rv2496c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_3843|M.marinum_M --------------------------------------------------
MUL_3774|M.ulcerans_Agy99 --------------------------------------------------
MAB_0896c|M.abscessus_ATCC_199 --------------------------------------------------
Mflv_3923|M.gilvum_PYR-GCK LQPGYERVLEEGRKAVRGVPMIGEFCYQCMHSIKAGIKDALSPQVMFTDL
MLBr_01038|M.leprae_Br4923 LQPAYERLLEKGRDALHSLPLIGQIAYRFMHSVKAGIKDSLSPQLLFTDL
TH_4167|M.thermoresistible__bu AAQVDAAFAAARDAEPLGPEELTGDVFTGNGTELADGT------------
MAV_2948|M.avium_104 ---------------------------------MAD--------------
MSMEG_4711|M.smegmatis_MC2_155 ------------------------------MTQIIDRP-AAQGDAPEPWG
Mvan_4085|M.vanbaalenii_PYR-1 ------------------------------MTQLIERPFGFDDDAAEPQ-
Mb2524c|M.bovis_AF2122/97 ------------------------------MTQIADRP-------ARPD-
Rv2496c|M.tuberculosis_H37Rv ------------------------------MTQIADRP-------ARPD-
MMAR_3843|M.marinum_M ------------------------------MTQIADPP-------ARPG-
MUL_3774|M.ulcerans_Agy99 ------------------------------MTQIADPP-------ARPG-
MAB_0896c|M.abscessus_ATCC_199 --------------------------------------------------
Mflv_3923|M.gilvum_PYR-GCK GLKYVGPIDGHDESAVEGALRHARAFNAPVVVHVVTRKGMG---------
MLBr_01038|M.leprae_Br4923 GLKYVGPVDGHDEHAVEVALRKARGFGGPVIVHVVTRKGMG---------
TH_4167|M.thermoresistible__bu ----VPRVALPEGETEELGLVQAIHRTLDRAMAADDSIILLGEDIGD--R
MAV_2948|M.avium_104 ---------------QEMTMREALNLALDQALAADERVFLLGEDIAD--P
MSMEG_4711|M.smegmatis_MC2_155 SILTPAAAQAPVPAVTELTMVQAINRALRDAMAADERVLVFGEDVA----
Mvan_4085|M.vanbaalenii_PYR-1 ----RTPVAVPVAPIAPISMAQAINRALHDAMRVDDRVLVFGEDVA----
Mb2524c|M.bovis_AF2122/97 ----ETLAVAVSDITQSLTMVQAINRALYDAMAADERVLVFGEDVA----
Rv2496c|M.tuberculosis_H37Rv ----ETLAVAVSDITQSLTMVQAINRALYDAMAADERVLVFGEDVA----
MMAR_3843|M.marinum_M ----PAPAAPVVGTMQSLTMVQALNQALHDAMAADDRVLVFGEDVG----
MUL_3774|M.ulcerans_Agy99 ----PAPAAPVVGTMQSLTMVQALNQALHDAMAADDRVLVFGEDVG----
MAB_0896c|M.abscessus_ATCC_199 --------------MTVTTMAQALNAALRDALHDDDSVVVFGEDVG----
Mflv_3923|M.gilvum_PYR-GCK ----YAPAENDVDEQMHACGVIDPETGLATSVPGPGWTAAFSETLIELAA
MLBr_01038|M.leprae_Br4923 ----YPPAEADQAEQMHTCGVMDPTTGQPTKIAAPDWTAIFSDALIGYAM
: :.: :
TH_4167|M.thermoresistible__bu SGGGMFKITAGLSAKYGE--------ERVRDTPIAESSIIGAALGASLAG
MAV_2948|M.avium_104 GASG---PTAGLSTKYGC--------DRVLDTPISEAAIVGAAIGAAIDG
MSMEG_4711|M.smegmatis_MC2_155 TLGGVFRVTDGLTESFGA--------ERCFDTPLAESAIIGIAVGFAIRG
Mvan_4085|M.vanbaalenii_PYR-1 TLGGVFRVTEGLAETYGE--------QRCFDTPLAESAIIGIAVGMAIRG
Mb2524c|M.bovis_AF2122/97 VEGGVFRVTEGLADTFGA--------DRCFDTPLAESAIIGIAVGLALRG
Rv2496c|M.tuberculosis_H37Rv VEGGVFRVTEGLADTFGA--------DRCFDTPLAESAIIGIAVGLALRG
MMAR_3843|M.marinum_M IAGGVFRVTEGLAETFGE--------HRCFDTPLAESALIGIAVGLALRG
MUL_3774|M.ulcerans_Agy99 IAGGVFRVTEGLAETFGE--------HRCFDTPLAESALIGIAVGLALRG
MAB_0896c|M.abscessus_ATCC_199 TLGGVFRVTDGLTETFGA--------NRCFDTPLAESGIIGFAVGMAMGG
Mflv_3923|M.gilvum_PYR-GCK KRRDIVAITAAMPGPTGLSAFRKRFPDRFFDVGIAEQHAMTSAAGLAMGG
MLBr_01038|M.leprae_Br4923 KRRDIVAITAAMPGPTGLTAFGQCFPDRLFDVGIAEQHAMTSAAGLAMGR
. * .:. * .* *. ::* : * * ::
TH_4167|M.thermoresistible__bu LRPVAELMFMDFLGVAMDQIANHVAKVRYMSGGRRGAPLVIRTMV--GTA
MAV_2948|M.avium_104 LLPVAEIMIMDFIGIAADQLINNAAKLRFMTAGRTSAPLTVRTQVYAGLS
MSMEG_4711|M.smegmatis_MC2_155 FVPVPEIQFDGFSYPAFDQIASHLAKYRMRTHGDIDMPVTVRIPSFGGIG
Mvan_4085|M.vanbaalenii_PYR-1 LVPVPEIQFDGFAAPAFDQMVSHLAKYRMRTRGDVDMPVTVRIPSFGGIG
Mb2524c|M.bovis_AF2122/97 FVPVPEIQFDGFSYPAFDQVVSHLAKYRTRTRGEVDMPVTVRIPSFGGIG
Rv2496c|M.tuberculosis_H37Rv FVPVPEIQFDGFSYPAFDQVVSHLAKYRTRTRGEVDMPVTVRIPSFGGIG
MMAR_3843|M.marinum_M FVPVPEIQFDGFSYPAFDQVVSHLAKYRTRTRGEVNMAVTVRIPSFGGIG
MUL_3774|M.ulcerans_Agy99 FVPVPEIQFDDFSYPAFDQVVSHLAKYRTRTRGEVNMAVTVRIPSFGGIG
MAB_0896c|M.abscessus_ATCC_199 FRPVVEMQFDAFAYPAFEQVVSHVAKLRNRTRGVLSVPMVIRVPYAGGIG
Mflv_3923|M.gilvum_PYR-GCK MHPVVALYST-FLNRAFDQMLMDVALHKLP------VTMVLDRSGITGPD
MLBr_01038|M.leprae_Br4923 MHPVVAIYST-FLNRAFDQIMMDVALHKLP------VTMVIDRAGITGSD
: ** : * * :*: . * : .:.: *
TH_4167|M.thermoresistible__bu AGAQHSQALEAWAMHTPGLKVVWPSTAADAAGLLNACLREDDPCLFIESM
MAV_2948|M.avium_104 TGATHSQSLEAWFMHIPGLKVIVPATPRDGKGLLSSAIFDPDPCLFIETI
MSMEG_4711|M.smegmatis_MC2_155 AVEHHSESTETYWLHTAGLKVVVPSTPSDAYWLLRESISSPDPVIYLEPK
Mvan_4085|M.vanbaalenii_PYR-1 AVEHHSESTETYWLHTAGLKVVTPSTPTDAYWLLRYAIASRDPVIFLEPK
Mb2524c|M.bovis_AF2122/97 AAEHHSDSTESYWVHTAGLKVVVPSTPGDAYWLLRHAIACPDPVMYLEPK
Rv2496c|M.tuberculosis_H37Rv AAEHHSDSTESYWVHTAGLKVVVPSTPGDAYWLLRHAIACPDPVMYLEPK
MMAR_3843|M.marinum_M AAEHHSDSTESYWAHTAGLKVVVPSTPGDAYWLLRHAIACPDPVMYLEPK
MUL_3774|M.ulcerans_Agy99 AAEHHLDATESYWAHTAGLKVVVPSTPGDAYWLLRHAIACPDPVMYLEPK
MAB_0896c|M.abscessus_ATCC_199 GVEHHCDSSEAYYAHTPGLKVVTPATVADAYGLLREAIDDPDPVVFLEPK
Mflv_3923|M.gilvum_PYR-GCK GASHNGMWDLSILGIVPGMRVAAPRDGARLREELAEAVEVKDGPTAVRFP
MLBr_01038|M.leprae_Br4923 GPSHNGMWDLSMLGIVPGMRVAAPRDAIRLREELGEALDVDDGPTAIRFP
: : .*::* * * .: * :.
TH_4167|M.thermoresistible__bu KLYYGGGKGPVPVAD-YVIPLGQADVKRVGSDVTICTYGVLVHAALEAAK
MAV_2948|M.avium_104 RLQ--GKKGLVPVEPGFRIPLGQADIKRPGTDVSLIGYGRPVHDALAAAA
MSMEG_4711|M.smegmatis_MC2_155 RRY--WAREAVDTTT-PALPIGRAAVRRNGSDVTVITYGGLVATALSAAE
Mvan_4085|M.vanbaalenii_PYR-1 RRY--WAKEVVDTGN-PADPIGRAAIRRAGDDVTVLTYGPLVATALNAAE
Mb2524c|M.bovis_AF2122/97 RRY--HSRGMVDTSR-PEPPIGHAMVRRSGTDVTVVTYGNLVSTALSSAD
Rv2496c|M.tuberculosis_H37Rv RRY--HGRGMVDTSR-PEPPIGHAMVRRSGTDVTVVTYGNLVSTALSSAD
MMAR_3843|M.marinum_M RRY--QVRGPVDTSR-PEPAIGQAMIRRAGADVTVITYGNLVSTALSAAE
MUL_3774|M.ulcerans_Agy99 RRY--QVRGPVDTSR-PEPAIGQAMIRRAGADVTVITYGNLVSTALSAAE
MAB_0896c|M.abscessus_ATCC_199 RLY--FSRADVELGR--GAKIGEAQVLRAGTDVTLIAYGPSVEPALQAAA
Mflv_3923|M.gilvum_PYR-GCK KGD--VGEDIPAIERRDGVDVLAVPADGLSDDVLIIAVGAFAAMSVAVAE
MLBr_01038|M.leprae_Br4923 KGD--VCEDIPALKRRSGVDVLAVPATGLAQDVLLVGVGVFASMALAVAK
: . : . . ** : * . :: *
TH_4167|M.thermoresistible__bu TLAGEG-VSVEVVDLRTLVPLDLQTVLDSVRKTKRLVVAHESVGFCGPGA
MAV_2948|M.avium_104 MLGDQG-VSAEVVDLRTLVPLDVDTVVASVRRTRRAVIVHDAVQFAGPGA
MSMEG_4711|M.smegmatis_MC2_155 LAEDRG-WSMEVVDLRSLNPLDFDTVADSVRRTGRAVVMHEGPRTLGFGA
Mvan_4085|M.vanbaalenii_PYR-1 LSPHG----LEVVDLRSLNPLDFDTVAASVRKTGRAVVMHEGARTVGFGA
Mb2524c|M.bovis_AF2122/97 TAEQQHDWSLEVIDLRSLAPLDFDTIAASIQRTGRCVVMHEGPRSLGYGA
Rv2496c|M.tuberculosis_H37Rv TAEQQHDWSLEVIDLRSLAPLDFDTIAASIQRTGRCVVMHEGPRSLGYGA
MMAR_3843|M.marinum_M DAAHQQGWSLEVIDLRSLIPLDFETIAASIRRTGRCVVLHEGPRSLGYGA
MUL_3774|M.ulcerans_Agy99 DAAHQQGWSLEVIDLRSLIPLDFETIAASIRRTGRCVVLHEGPRSLGYGA
MAB_0896c|M.abscessus_ATCC_199 AAADEG-RDIEVVDLRSIAPFDDQSVTASVRKTGRCVIVQEAQGFGGVGA
Mflv_3923|M.gilvum_PYR-GCK RLRDQG-IGVTVVDPRWVLPVP-AAINTLAAAHKLVVTVEDNGGHGGVGS
MLBr_01038|M.leprae_Br4923 RLHNQG-IGVTVIDPRWVLPVC-DGVLELAHTHKLIVTLEDNGVNGGVGA
*:* * : *. : * .: * *:
TH_4167|M.thermoresistible__bu EIAAAVGTELFAELAAPIQRVAGTYTPVPRAATLEAACRPDATKLSDAVR
MAV_2948|M.avium_104 EVAAILHSRLFSELAAPVERVAARFVPNPAAAALEAQVYPSPERIAAAAL
MSMEG_4711|M.smegmatis_MC2_155 ELAARISEELFYDLEAPVLRATGFDTPYP-PARLEKLWLPGVDRLLDCVE
Mvan_4085|M.vanbaalenii_PYR-1 ELAARISEECFYDLEAPVLRATGFDTPYP-PARLEKLWLPGVDRLLDCVD
Mb2524c|M.bovis_AF2122/97 GLAARIQEEMFYQLEAPVLRACGFDTPYP-PARLEKLWLPGPDRLLDCVE
Rv2496c|M.tuberculosis_H37Rv GLAARIQEEMFYQLEAPVLRACGFDTPYP-PARLEKLWLPGPDRLLDCVE
MMAR_3843|M.marinum_M GLAARIQEELFYELEAPVLRACGFDTPYP-PARLERLWLPGPDRLLDCVE
MUL_3774|M.ulcerans_Agy99 GLAARIQEELFYELEAPVLRACGFDTPYP-PARLERLWLPGPDRLLDCVE
MAB_0896c|M.abscessus_ATCC_199 EIAARIQERCFHHLAAPVLRVSGYDIPYP-APRLERWYLPSTDRILDAVD
Mflv_3923|M.gilvum_PYR-GCK AVSAALRRAEIDVPCRDAALPQAFFDHASRGEVLAEVGLTERTIARQITG
MLBr_01038|M.leprae_Br4923 AVSTALRQVEIDTPCRDVGLPQEFYDHASRSEVLADLGLTDQDVARRITG
::: : : . * . .
TH_4167|M.thermoresistible__bu RIM----------------------
MAV_2948|M.avium_104 KTLGRTLTGATAHG-----------
MSMEG_4711|M.smegmatis_MC2_155 RAMEQP-------------------
Mvan_4085|M.vanbaalenii_PYR-1 KAMGQP-------------------
Mb2524c|M.bovis_AF2122/97 RVLRQP-------------------
Rv2496c|M.tuberculosis_H37Rv RVLRQP-------------------
MMAR_3843|M.marinum_M RVLGQP-------------------
MUL_3774|M.ulcerans_Agy99 RVLGQP-------------------
MAB_0896c|M.abscessus_ATCC_199 RLQWDDHPDSRWVVSA---------
Mflv_3923|M.gilvum_PYR-GCK WVAALG-----ATAGDRQVSESVD-
MLBr_01038|M.leprae_Br4923 WVVAFGHCGSGDDAGQYGPRSSQTM