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M. vanbaalenii PYR-1 Mvan_4085 (-)

annotation: transketolase, central region
coordinates: 4377132 - 4378187
length: 351

TQLIERPFGFDDDAAEPQRTPVAVPVAPIAPISMAQAINRALHDAMRVDDRVLVFGEDVATLGGVFRVTE
GLAETYGEQRCFDTPLAESAIIGIAVGMAIRGLVPVPEIQFDGFAAPAFDQMVSHLAKYRMRTRGDVDMP
VTVRIPSFGGIGAVEHHSESTETYWLHTAGLKVVTPSTPTDAYWLLRYAIASRDPVIFLEPKRRYWAKEV
VDTGNPADPIGRAAIRRAGDDVTVLTYGPLVATALNAAELSPHGLEVVDLRSLNPLDFDTVAASVRKTGR
AVVMHEGARTVGFGAELAARISEECFYDLEAPVLRATGFDTPYPPARLEKLWLPGVDRLLDCVDKAMGQP
*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. vanbaalenii PYR-1Mvan_4085--100% (351)transketolase, central region
M. vanbaalenii PYR-1Mvan_1409-3e-6041.74% (321) transketolase, central region
M. vanbaalenii PYR-1Mvan_0912-1e-4335.20% (321) transketolase, central region

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb2524cpdhB1e-14370.79% (356) pyruvate dehydrogenase E1 component beta subunit PdhB
M. gilvum PYR-GCK-----
M. tuberculosis H37RvRv2496cpdhB1e-14370.79% (356) pyruvate dehydrogenase E1 component beta subunit PdhB
M. leprae Br4923-----
M. abscessus ATCC 19977MAB_0896c-1e-10259.49% (316) putative pyruvate dehydrogenase E1 component, beta subunit
M. marinum MMMAR_3843pdhB1e-14370.42% (355) pyruvate dehydrogenase E1 component (beta subunit) PdhB
M. avium 104MAV_1676-1e-14470.99% (355) pyruvate dehydrogenase E1 component subunit beta
M. smegmatis MC2 155MSMEG_4711-1e-15878.55% (359) pyruvate dehydrogenase E1 component subunit beta
M. thermoresistible (build 8)TH_0717pdhB1e-15275.21% (355) PROBABLE PYRUVATE DEHYDROGENASE E1 COMPONENT (BETA SUBUNIT)
M. ulcerans Agy99MUL_3774pdhB1e-14169.58% (355) pyruvate dehydrogenase E1 component (beta subunit) PdhB

CLUSTAL 2.0.9 multiple sequence alignment


Mb2524c|M.bovis_AF2122/97           --MTQIADRPARPDE------------TLAVAVSDI---TQSLTMVQAIN
Rv2496c|M.tuberculosis_H37Rv        --MTQIADRPARPDE------------TLAVAVSDI---TQSLTMVQAIN
MMAR_3843|M.marinum_M               --MTQIADPPARPGP------------APAAPVVGT---MQSLTMVQALN
MUL_3774|M.ulcerans_Agy99           --MTQIADPPARPGP------------APAAPVVGT---MQSLTMVQALN
MAV_1676|M.avium_104                --MTQLADRPTGHGE------------TLTAAVQDVALGAQALTMVQALN
MSMEG_4711|M.smegmatis_MC2_155      --MTQIIDRPAAQGDAPEPWGSILTPAAAQAPVPAV----TELTMVQAIN
TH_0717|M.thermoresistible__bu      MTVTQLIERPLVT---------------ARPPVP-------ELTLAQAVN
Mvan_4085|M.vanbaalenii_PYR-1       --MTQLIERPFGFDDDAAE----PQRTPVAVPVAPI----APISMAQAIN
MAB_0896c|M.abscessus_ATCC_199      ---------------------------------------MTVTTMAQALN
                                                                               ::.**:*

Mb2524c|M.bovis_AF2122/97           RALYDAMAADERVLVFGEDVAVEGGVFRVTEGLADTFGADRCFDTPLAES
Rv2496c|M.tuberculosis_H37Rv        RALYDAMAADERVLVFGEDVAVEGGVFRVTEGLADTFGADRCFDTPLAES
MMAR_3843|M.marinum_M               QALHDAMAADDRVLVFGEDVGIAGGVFRVTEGLAETFGEHRCFDTPLAES
MUL_3774|M.ulcerans_Agy99           QALHDAMAADDRVLVFGEDVGIAGGVFRVTEGLAETFGEHRCFDTPLAES
MAV_1676|M.avium_104                RALHDAMAADERVLVFGEDVAVQGGVFRVTEGLAEAFGESRCFDTPLAES
MSMEG_4711|M.smegmatis_MC2_155      RALRDAMAADERVLVFGEDVATLGGVFRVTDGLTESFGAERCFDTPLAES
TH_0717|M.thermoresistible__bu      RALHDAMAADQRVLVFGQDVARLGGVFRVTDGLSAAFGEERCFDTPLAES
Mvan_4085|M.vanbaalenii_PYR-1       RALHDAMRVDDRVLVFGEDVATLGGVFRVTEGLAETYGEQRCFDTPLAES
MAB_0896c|M.abscessus_ATCC_199      AALRDALHDDDSVVVFGEDVGTLGGVFRVTDGLTETFGANRCFDTPLAES
                                     ** **:  *: *:***:**.  *******:**: ::*  **********

Mb2524c|M.bovis_AF2122/97           AIIGIAVGLALRGFVPVPEIQFDGFSYPAFDQVVSHLAKYRTRTRGEVDM
Rv2496c|M.tuberculosis_H37Rv        AIIGIAVGLALRGFVPVPEIQFDGFSYPAFDQVVSHLAKYRTRTRGEVDM
MMAR_3843|M.marinum_M               ALIGIAVGLALRGFVPVPEIQFDGFSYPAFDQVVSHLAKYRTRTRGEVNM
MUL_3774|M.ulcerans_Agy99           ALIGIAVGLALRGFVPVPEIQFDDFSYPAFDQVVSHLAKYRTRTRGEVNM
MAV_1676|M.avium_104                AIIGIAVGLALRGFVPVPEIQFDGFSYPAFDQVVSHLAKYRTRTRGAIDM
MSMEG_4711|M.smegmatis_MC2_155      AIIGIAVGFAIRGFVPVPEIQFDGFSYPAFDQIASHLAKYRMRTHGDIDM
TH_0717|M.thermoresistible__bu      AIIGIAIGLAIRGFVPVPEIQFDGFSYPAFDQIVSHLAKYRMRTRGDVEM
Mvan_4085|M.vanbaalenii_PYR-1       AIIGIAVGMAIRGLVPVPEIQFDGFAAPAFDQMVSHLAKYRMRTRGDVDM
MAB_0896c|M.abscessus_ATCC_199      GIIGFAVGMAMGGFRPVVEMQFDAFAYPAFEQVVSHVAKLRNRTRGVLSV
                                    .:**:*:*:*: *: ** *:*** *: ***:*:.**:** * **:* :.:

Mb2524c|M.bovis_AF2122/97           PVTVRIPSFGGIGAAEHHSDSTESYWVHTAGLKVVVPSTPGDAYWLLRHA
Rv2496c|M.tuberculosis_H37Rv        PVTVRIPSFGGIGAAEHHSDSTESYWVHTAGLKVVVPSTPGDAYWLLRHA
MMAR_3843|M.marinum_M               AVTVRIPSFGGIGAAEHHSDSTESYWAHTAGLKVVVPSTPGDAYWLLRHA
MUL_3774|M.ulcerans_Agy99           AVTVRIPSFGGIGAAEHHLDATESYWAHTAGLKVVVPSTPGDAYWLLRHA
MAV_1676|M.avium_104                PVTVRVPSFGGIGAAEHHSESTESYWAHTAGLKVVVPSNPADAYWLLRHA
MSMEG_4711|M.smegmatis_MC2_155      PVTVRIPSFGGIGAVEHHSESTETYWLHTAGLKVVVPSTPSDAYWLLRES
TH_0717|M.thermoresistible__bu      RVTVRIPSFGGIGAVEHHSESTETYWLHTAGLKVVAPGTPADAYWLLRHA
Mvan_4085|M.vanbaalenii_PYR-1       PVTVRIPSFGGIGAVEHHSESTETYWLHTAGLKVVTPSTPTDAYWLLRYA
MAB_0896c|M.abscessus_ATCC_199      PMVIRVPYAGGIGGVEHHCDSSEAYYAHTPGLKVVTPATVADAYGLLREA
                                     :.:*:*  ****..*** :::*:*: **.*****.*..  *** *** :

Mb2524c|M.bovis_AF2122/97           IACPDPVMYLEPKRRYHSRGMVDTSRPEPPIGHAMVRRSGTDVTVVTYGN
Rv2496c|M.tuberculosis_H37Rv        IACPDPVMYLEPKRRYHGRGMVDTSRPEPPIGHAMVRRSGTDVTVVTYGN
MMAR_3843|M.marinum_M               IACPDPVMYLEPKRRYQVRGPVDTSRPEPAIGQAMIRRAGADVTVITYGN
MUL_3774|M.ulcerans_Agy99           IACPDPVMYLEPKRRYQVRGPVDTSRPEPAIGQAMIRRAGADVTVITYGN
MAV_1676|M.avium_104                IACPDPVMYLEPKRRYQGRGLVDAGRPEPPIGRAMVRRAGTDVTVVTYGS
MSMEG_4711|M.smegmatis_MC2_155      ISSPDPVIYLEPKRRYWAREAVDTTTPALPIGRAAVRRNGSDVTVITYGG
TH_0717|M.thermoresistible__bu      ITCPDPVIYLEPKRRYWARGPVDTTTPAGPLGRAAVARSGTDVTVITYGS
Mvan_4085|M.vanbaalenii_PYR-1       IASRDPVIFLEPKRRYWAKEVVDTGNPADPIGRAAIRRAGDDVTVLTYGP
MAB_0896c|M.abscessus_ATCC_199      IDDPDPVVFLEPKRLYFSRADVELGR-GAKIGEAQVLRAGTDVTLIAYGP
                                    *   ***::***** *  :  *:       :*.* : * * ***:::** 

Mb2524c|M.bovis_AF2122/97           LVSTALSSADTAEQQHDWSLEVIDLRSLAPLDFDTIAASIQRTGRCVVMH
Rv2496c|M.tuberculosis_H37Rv        LVSTALSSADTAEQQHDWSLEVIDLRSLAPLDFDTIAASIQRTGRCVVMH
MMAR_3843|M.marinum_M               LVSTALSAAEDAAHQQGWSLEVIDLRSLIPLDFETIAASIRRTGRCVVLH
MUL_3774|M.ulcerans_Agy99           LVSTALSAAEDAAHQQGWSLEVIDLRSLIPLDFETIAASIRRTGRCVVLH
MAV_1676|M.avium_104                LVATAVGAAEEAQHQRGWSLEVIDLRSLVPLDFDTIATSIHRTGRCVVMH
MSMEG_4711|M.smegmatis_MC2_155      LVATALSAAELAED-RGWSMEVVDLRSLNPLDFDTVADSVRRTGRAVVMH
TH_0717|M.thermoresistible__bu      LVTTALSAAELAADTHGWSLEVVDLRSLNPLDFDTIAESVRRTGRAVVLH
Mvan_4085|M.vanbaalenii_PYR-1       LVATALNAAELSPH----GLEVVDLRSLNPLDFDTVAASVRKTGRAVVMH
MAB_0896c|M.abscessus_ATCC_199      SVEPALQAAAAAAD-EGRDIEVVDLRSIAPFDDQSVTASVRKTGRCVIVQ
                                     * .*: :*  : .    .:**:****: *:* :::: *:::***.*:::

Mb2524c|M.bovis_AF2122/97           EGPRSLGYGAGLAARIQEEMFYQLEAPVLRACGFDTPYPPARLEKLWLPG
Rv2496c|M.tuberculosis_H37Rv        EGPRSLGYGAGLAARIQEEMFYQLEAPVLRACGFDTPYPPARLEKLWLPG
MMAR_3843|M.marinum_M               EGPRSLGYGAGLAARIQEELFYELEAPVLRACGFDTPYPPARLERLWLPG
MUL_3774|M.ulcerans_Agy99           EGPRSLGYGAGLAARIQEELFYELEAPVLRACGFDTPYPPARLERLWLPG
MAV_1676|M.avium_104                EGPRTLGYGAELAARIQEELFYELEAPVLRACGFDTPYPPARLEKWWLPG
MSMEG_4711|M.smegmatis_MC2_155      EGPRTLGFGAELAARISEELFYDLEAPVLRATGFDTPYPPARLEKLWLPG
TH_0717|M.thermoresistible__bu      EGPRTLGFGAELAARITEELFYDLEAPVLRATGFDTPYPPARLEKLWLPG
Mvan_4085|M.vanbaalenii_PYR-1       EGARTVGFGAELAARISEECFYDLEAPVLRATGFDTPYPPARLEKLWLPG
MAB_0896c|M.abscessus_ATCC_199      EAQGFGGVGAEIAARIQERCFHHLAAPVLRVSGYDIPYPAPRLERWYLPS
                                    *.    * ** :**** *. *:.* *****. *:* ***..***: :**.

Mb2524c|M.bovis_AF2122/97           PDRLLDCVERVLRQP----------
Rv2496c|M.tuberculosis_H37Rv        PDRLLDCVERVLRQP----------
MMAR_3843|M.marinum_M               PDRLLDCVERVLGQP----------
MUL_3774|M.ulcerans_Agy99           PDRLLDCVERVLGQP----------
MAV_1676|M.avium_104                PDRLLDCVERTLELP----------
MSMEG_4711|M.smegmatis_MC2_155      VDRLLDCVERAMEQP----------
TH_0717|M.thermoresistible__bu      PDRLLDCVERSLGYP----------
Mvan_4085|M.vanbaalenii_PYR-1       VDRLLDCVDKAMGQP----------
MAB_0896c|M.abscessus_ATCC_199      TDRILDAVDRLQWDDHPDSRWVVSA
                                     **:**.*::