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M. thermoresistible (build 8) TH_0717 (pdhB)

annotation: PROBABLE PYRUVATE DEHYDROGENASE E1 COMPONENT (BETA SUBUNIT) PDHB (PYRUVATE DECARBOXYLASE) (PYRUVATE DEHYDROGENASE) (PYRUVIC DEHYDROGENASE)
coordinates: 1538463 - 1539494
length: 344

aa seq not available

Operon Prediction Model: Genebank

Paralogs

species id gene e-value identity (len) annotation
M. thermoresistible (build 8) TH_0717 pdhB - 100% (344) PROBABLE PYRUVATE DEHYDROGENASE E1 COMPONENT (BETA SUBUNIT) PDHB (PYRUVATE DECARBOXYLASE) (PYRUVATE DEHYDROGENASE) (PYRUVIC DEHYDROGENASE)
M. thermoresistible (build 8) TH_4167 - 9e-65 45.06% (324) PUTATIVE acetoin:2,6-dichlorophenolindophenol oxidoreductase

Closest Orthologs (e-value cutoff: 1e-4)

species id gene e-value identity (len) annotation
M. bovis AF2122 / 97 Mb2524c pdhB 1e-153 74.71% (348) pyruvate dehydrogenase E1 component beta subunit PdhB
M. gilvum PYR-GCK - - - - -
M. tuberculosis H37Rv Rv2496c pdhB 1e-153 74.71% (348) pyruvate dehydrogenase E1 component beta subunit PdhB
M. leprae Br4923 - - - - -
M. abscessus ATCC 19977 MAB_4917c - 1e-106 58.75% (320) pyruvate dehydrogenase E1 component beta subunit
M. marinum M MMAR_3843 pdhB 1e-153 75.50% (351) pyruvate dehydrogenase E1 component (beta subunit) PdhB
M. avium 104 MAV_1676 - 1e-153 76.07% (351) pyruvate dehydrogenase E1 component subunit beta
M. smegmatis MC2 155 MSMEG_4711 - 1e-163 79.67% (359) pyruvate dehydrogenase E1 component subunit beta
M. ulcerans Agy99 MUL_3774 pdhB 1e-151 74.64% (351) pyruvate dehydrogenase E1 component (beta subunit) PdhB
M. vanbaalenii PYR-1 Mvan_4085 - 1e-152 75.21% (355) transketolase, central region

CLUSTAL 2.0.9 multiple sequence alignment


TH_0717|M.thermoresistible__bu      MTVTQLIERPLVT---------------ARPPVP-------ELTLAQAVN
MSMEG_4711|M.smegmatis_MC2_155      --MTQIIDRPAAQGDAPEPWGSILTPAAAQAPVPAV----TELTMVQAIN
Mb2524c|M.bovis_AF2122/97           --MTQIADRPARPDE------------TLAVAVSDI---TQSLTMVQAIN
Rv2496c|M.tuberculosis_H37Rv        --MTQIADRPARPDE------------TLAVAVSDI---TQSLTMVQAIN
MMAR_3843|M.marinum_M               --MTQIADPPARPGP------------APAAPVVGT---MQSLTMVQALN
MUL_3774|M.ulcerans_Agy99           --MTQIADPPARPGP------------APAAPVVGT---MQSLTMVQALN
MAV_1676|M.avium_104                --MTQLADRPTGHGE------------TLTAAVQDVALGAQALTMVQALN
Mvan_4085|M.vanbaalenii_PYR-1       --MTQLIERPFGFDDDAAE--------PQRTPVAVPVAPIAPISMAQAIN
MAB_4917c|M.abscessus_ATCC_199      ---------------------------------------MTRMTMSGALD
                                                                              :::  *::

TH_0717|M.thermoresistible__bu      RALHDAMAADQRVLVFGQDVARLGGVFRVTDGLSAAFGEERCFDTPLAES
MSMEG_4711|M.smegmatis_MC2_155      RALRDAMAADERVLVFGEDVATLGGVFRVTDGLTESFGAERCFDTPLAES
Mb2524c|M.bovis_AF2122/97           RALYDAMAADERVLVFGEDVAVEGGVFRVTEGLADTFGADRCFDTPLAES
Rv2496c|M.tuberculosis_H37Rv        RALYDAMAADERVLVFGEDVAVEGGVFRVTEGLADTFGADRCFDTPLAES
MMAR_3843|M.marinum_M               QALHDAMAADDRVLVFGEDVGIAGGVFRVTEGLAETFGEHRCFDTPLAES
MUL_3774|M.ulcerans_Agy99           QALHDAMAADDRVLVFGEDVGIAGGVFRVTEGLAETFGEHRCFDTPLAES
MAV_1676|M.avium_104                RALHDAMAADERVLVFGEDVAVQGGVFRVTEGLAEAFGESRCFDTPLAES
Mvan_4085|M.vanbaalenii_PYR-1       RALHDAMRVDDRVLVFGEDVATLGGVFRVTEGLAETYGEQRCFDTPLAES
MAB_4917c|M.abscessus_ATCC_199      AGLRSALEDDDKVIVMGEDVGKLGGVFRVTDGLQKDFGDHRVIDTPLAES
                                     .* .*:  *::*:*:*:**.  *******:**   :*  * :*******

TH_0717|M.thermoresistible__bu      AIIGIAIGLAIRGFVPVPEIQFDGFSYPAFDQIVSHLAKYRMRTRGDVEM
MSMEG_4711|M.smegmatis_MC2_155      AIIGIAVGFAIRGFVPVPEIQFDGFSYPAFDQIASHLAKYRMRTHGDIDM
Mb2524c|M.bovis_AF2122/97           AIIGIAVGLALRGFVPVPEIQFDGFSYPAFDQVVSHLAKYRTRTRGEVDM
Rv2496c|M.tuberculosis_H37Rv        AIIGIAVGLALRGFVPVPEIQFDGFSYPAFDQVVSHLAKYRTRTRGEVDM
MMAR_3843|M.marinum_M               ALIGIAVGLALRGFVPVPEIQFDGFSYPAFDQVVSHLAKYRTRTRGEVNM
MUL_3774|M.ulcerans_Agy99           ALIGIAVGLALRGFVPVPEIQFDDFSYPAFDQVVSHLAKYRTRTRGEVNM
MAV_1676|M.avium_104                AIIGIAVGLALRGFVPVPEIQFDGFSYPAFDQVVSHLAKYRTRTRGAIDM
Mvan_4085|M.vanbaalenii_PYR-1       AIIGIAVGMAIRGLVPVPEIQFDGFAAPAFDQMVSHLAKYRMRTRGDVDM
MAB_4917c|M.abscessus_ATCC_199      GIIGTAVGLAMRGYRPVCEIQFDGFVYPAFDQIVSQVAKLHYRTKGAVGM
                                    .:** *:*:*:**  ** *****.*  *****:.*::** : **:* : *

TH_0717|M.thermoresistible__bu      RVTVRIPSFGGIGAVEHHSESTETYWLHTAGLKVVAPGTPADAYWLLRHA
MSMEG_4711|M.smegmatis_MC2_155      PVTVRIPSFGGIGAVEHHSESTETYWLHTAGLKVVVPSTPSDAYWLLRES
Mb2524c|M.bovis_AF2122/97           PVTVRIPSFGGIGAAEHHSDSTESYWVHTAGLKVVVPSTPGDAYWLLRHA
Rv2496c|M.tuberculosis_H37Rv        PVTVRIPSFGGIGAAEHHSDSTESYWVHTAGLKVVVPSTPGDAYWLLRHA
MMAR_3843|M.marinum_M               AVTVRIPSFGGIGAAEHHSDSTESYWAHTAGLKVVVPSTPGDAYWLLRHA
MUL_3774|M.ulcerans_Agy99           AVTVRIPSFGGIGAAEHHLDATESYWAHTAGLKVVVPSTPGDAYWLLRHA
MAV_1676|M.avium_104                PVTVRVPSFGGIGAAEHHSESTESYWAHTAGLKVVVPSNPADAYWLLRHA
Mvan_4085|M.vanbaalenii_PYR-1       PVTVRIPSFGGIGAVEHHSESTETYWLHTAGLKVVTPSTPTDAYWLLRYA
MAB_4917c|M.abscessus_ATCC_199      PLTIRIPFGGGIGAVEHHSESPEAYFAHTAGLRVVSCSSPQDAYDMIRQA
                                     :*:*:*  *****.*** ::.*:*: *****:**  ..* *** ::* :

TH_0717|M.thermoresistible__bu      ITCPDPVIYLEPKRRYWARGPVDTTTPAGPLGRAAVARSGTDVTVITYGS
MSMEG_4711|M.smegmatis_MC2_155      ISSPDPVIYLEPKRRYWAREAVDTTTPALPIGRAAVRRNGSDVTVITYGG
Mb2524c|M.bovis_AF2122/97           IACPDPVMYLEPKRRYHSRGMVDTSRPEPPIGHAMVRRSGTDVTVVTYGN
Rv2496c|M.tuberculosis_H37Rv        IACPDPVMYLEPKRRYHGRGMVDTSRPEPPIGHAMVRRSGTDVTVVTYGN
MMAR_3843|M.marinum_M               IACPDPVMYLEPKRRYQVRGPVDTSRPEPAIGQAMIRRAGADVTVITYGN
MUL_3774|M.ulcerans_Agy99           IACPDPVMYLEPKRRYQVRGPVDTSRPEPAIGQAMIRRAGADVTVITYGN
MAV_1676|M.avium_104                IACPDPVMYLEPKRRYQGRGLVDAGRPEPPIGRAMVRRAGTDVTVVTYGS
Mvan_4085|M.vanbaalenii_PYR-1       IASRDPVIFLEPKRRYWAKEVVDTGNPADPIGRAAIRRAGDDVTVLTYGP
MAB_4917c|M.abscessus_ATCC_199      VACDDPVVFFEPKRRYWEKGEVDTALVPVPLGAARVVRSGTAATIAAYGP
                                    ::. ***:::******  :  **:     .:* * : * *  .*: :** 

TH_0717|M.thermoresistible__bu      LVTTALSAAELAADTHGWSLEVVDLRSLNPLDFDTIAESVRRTGRAVVLH
MSMEG_4711|M.smegmatis_MC2_155      LVATALSAAELAED-RGWSMEVVDLRSLNPLDFDTVADSVRRTGRAVVMH
Mb2524c|M.bovis_AF2122/97           LVSTALSSADTAEQQHDWSLEVIDLRSLAPLDFDTIAASIQRTGRCVVMH
Rv2496c|M.tuberculosis_H37Rv        LVSTALSSADTAEQQHDWSLEVIDLRSLAPLDFDTIAASIQRTGRCVVMH
MMAR_3843|M.marinum_M               LVSTALSAAEDAAHQQGWSLEVIDLRSLIPLDFETIAASIRRTGRCVVLH
MUL_3774|M.ulcerans_Agy99           LVSTALSAAEDAAHQQGWSLEVIDLRSLIPLDFETIAASIRRTGRCVVLH
MAV_1676|M.avium_104                LVATAVGAAEEAQHQRGWSLEVIDLRSLVPLDFDTIATSIHRTGRCVVMH
Mvan_4085|M.vanbaalenii_PYR-1       LVATALNAAELSPH----GLEVVDLRSLNPLDFDTVAASVRKTGRAVVMH
MAB_4917c|M.abscessus_ATCC_199      MVAVANAAAELAAT-EGISVEVVDLRSLSPVDFDTLEASVRKTGRLIVVH
                                    :*:.*  :*: :      .:**:***** *:**:*:  *:::*** :*:*

TH_0717|M.thermoresistible__bu      EGPRTLGFGAELAARITEELFYDLEAPVLRATGFDTPYPPARLEKLWLPG
MSMEG_4711|M.smegmatis_MC2_155      EGPRTLGFGAELAARISEELFYDLEAPVLRATGFDTPYPPARLEKLWLPG
Mb2524c|M.bovis_AF2122/97           EGPRSLGYGAGLAARIQEEMFYQLEAPVLRACGFDTPYPPARLEKLWLPG
Rv2496c|M.tuberculosis_H37Rv        EGPRSLGYGAGLAARIQEEMFYQLEAPVLRACGFDTPYPPARLEKLWLPG
MMAR_3843|M.marinum_M               EGPRSLGYGAGLAARIQEELFYELEAPVLRACGFDTPYPPARLERLWLPG
MUL_3774|M.ulcerans_Agy99           EGPRSLGYGAGLAARIQEELFYELEAPVLRACGFDTPYPPARLERLWLPG
MAV_1676|M.avium_104                EGPRTLGYGAELAARIQEELFYELEAPVLRACGFDTPYPPARLEKWWLPG
Mvan_4085|M.vanbaalenii_PYR-1       EGARTVGFGAELAARISEECFYDLEAPVLRATGFDTPYPPARLEKLWLPG
MAB_4917c|M.abscessus_ATCC_199      EAPVFMGLGAEIAARITERCFYHLEAPVLRVGGFALPYPANKVEHHYLPD
                                    *..  :* ** :**** *. **.*******. **  ***. ::*: :**.

TH_0717|M.thermoresistible__bu      PDRLLDCVERSLGYP
MSMEG_4711|M.smegmatis_MC2_155      VDRLLDCVERAMEQP
Mb2524c|M.bovis_AF2122/97           PDRLLDCVERVLRQP
Rv2496c|M.tuberculosis_H37Rv        PDRLLDCVERVLRQP
MMAR_3843|M.marinum_M               PDRLLDCVERVLGQP
MUL_3774|M.ulcerans_Agy99           PDRLLDCVERVLGQP
MAV_1676|M.avium_104                PDRLLDCVERTLELP
Mvan_4085|M.vanbaalenii_PYR-1       VDRLLDCVDKAMGQP
MAB_4917c|M.abscessus_ATCC_199      AERVMDAVDRAIAA-
                                     :*::*.*:: :

species	id	gene	e-value	identity (len)	annotation
M. thermoresistible (build 8)	TH_0717	pdhB	-	100% (344)	PROBABLE PYRUVATE DEHYDROGENASE E1 COMPONENT (BETA SUBUNIT) PDHB (PYRUVATE DECARBOXYLASE) (PYRUVATE DEHYDROGENASE) (PYRUVIC DEHYDROGENASE)
M. thermoresistible (build 8)	TH_4167	-	9e-65	45.06% (324)	PUTATIVE acetoin:2,6-dichlorophenolindophenol oxidoreductase