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VPLSTARRTGLVDQVIEQLRRAVAGGEWRVGERIPNETVLVESLGVGRNTVREAVRALAHAGILEVRQGD GTYVRATSEVSGALRRLCGAELREVLQVRRALEVEGARLAAAHCTPADIAEMRTLLARRDECAATDDTDA FARTDAEFHLAVVRGSGNRTLTELYRGLIEVVTASVATTRHVPVEMVDHGVLVDQIAAGDAEQAARTAGE LLDRILAGVDSADSC
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_0952 | - | - | 100% (225) | GntR domain-containing protein |
| M. vanbaalenii PYR-1 | Mvan_4590 | - | 4e-17 | 30.96% (239) | GntR domain-containing protein |
| M. vanbaalenii PYR-1 | Mvan_2942 | - | 6e-16 | 31.86% (226) | regulatory protein GntR, HTH |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0601 | - | 5e-16 | 33.04% (227) | GntR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_0016 | - | 1e-94 | 79.02% (224) | GntR domain-containing protein |
| M. tuberculosis H37Rv | Rv0586 | - | 6e-16 | 33.04% (227) | GntR family transcriptional regulator |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_2272c | - | 5e-30 | 37.44% (219) | putative transcriptional regulator, GntR |
| M. marinum M | MMAR_0749 | - | 2e-32 | 39.29% (224) | GntR family transcriptional regulator |
| M. avium 104 | MAV_2560 | - | 2e-16 | 29.00% (231) | regulatory protein GntR, HTH |
| M. smegmatis MC2 155 | MSMEG_2794 | - | 4e-74 | 67.74% (217) | transcriptional regulator, GntR family protein |
| M. thermoresistible (build 8) | TH_2873 | - | 9e-17 | 30.00% (230) | PUTATIVE regulatory protein GntR, HTH |
| M. ulcerans Agy99 | MUL_1381 | - | 1e-32 | 40.00% (220) | GntR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
Mvan_0952|M.vanbaalenii_PYR-1 --------MPLSTARRTGLVDQVIEQLRRAVAGGEWRVGERIPNETVLVE
Mflv_0016|M.gilvum_PYR-GCK MIGRKDIRVPLSTARRSGLVEQVIDQLRHAVAGQEWRIGDRIPNETVLVE
MSMEG_2794|M.smegmatis_MC2_155 --------MPLASTRRTGLVDQVIEQLRASVSSGEWPVGTKIPTEPELAD
MMAR_0749|M.marinum_M ----------MQTVRRRTLIAQVSDQLRDEITSGRWKVGDRIPTEPELCE
MUL_1381|M.ulcerans_Agy99 -------------MRRRTLIAQVSDQLRDEITSGRWKVGDRIPTEPELCE
MAB_2272c|M.abscessus_ATCC_199 ----------MQPVRRQTLIGQVTEQLREEIVSGRWAIGARIPTEPELCE
Mb0601|M.bovis_AF2122/97 --------MALQPVTRRSVPEEVFEQIATDVLTGEMPPGEALPSERRLAE
Rv0586|M.tuberculosis_H37Rv --------MALQPVTRRSVPEEVFEQIATDVLTGEMPPGEALPSERRLAE
MAV_2560|M.avium_104 --------MEVTSLREPKMADRVATVLRRMFIRGEITEGTMLPPESELME
TH_2873|M.thermoresistible__bu ----VEDDMEVTSLREPKMADRVATVLRRMFIRGEIPEGTMLPPESELME
. : .* : . . * :* * * :
Mvan_0952|M.vanbaalenii_PYR-1 SLGVGRNTVREAVRALAHAGILEVRQ----GDGTYVRATSEVSG--ALRR
Mflv_0016|M.gilvum_PYR-GCK KFGVGRNTVREAVRALAHAGILEVRQ----GDGTYVRATSEVSG--ALRR
MSMEG_2794|M.smegmatis_MC2_155 TLGVGRNTLREAVRALAHSGILEVRQ----GDGTYVRATSEVSG--ALRR
MMAR_0749|M.marinum_M MTGTARNTVREAVQALVHVGILERRQ----GSGTYVIADVEQGS--ALAE
MUL_1381|M.ulcerans_Agy99 MTGTARNTVREAVQALVHVGILERRQ----GSGTYVIADVEQGS--ALAE
MAB_2272c|M.abscessus_ATCC_199 LTGTSRNTIREAVQALVHAGMLERRQ----GSGTYVLS-LGGSS--AIAD
Mb0601|M.bovis_AF2122/97 LLGVSRPAVREALKRLSAAGLVEVRQ----GDVTTVRDFRRHAGLDLLPR
Rv0586|M.tuberculosis_H37Rv LLGVSRPAVREALKRLSAAGLVEVRQ----GDVTTVRDFRRHAGLDLLPR
MAV_2560|M.avium_104 RFGVSRPTLREAFRVLESESLIQVQRGVRGGARVTRPRRETLARYAGLIL
TH_2873|M.thermoresistible__bu RFGVSRPTLREAFRVLESESLIVVQRGVRGGARVTRPRRETLARYAGLIL
*..* ::***.: * .:: :: * . . :
Mvan_0952|M.vanbaalenii_PYR-1 -LCGAELREVLQVRRALEVEGARLAAAHCTPADIAEMRTLLARRD-----
Mflv_0016|M.gilvum_PYR-GCK -LCGEELREVLEVRRALEVEAARLAASRRTPADVAEMRGLLARRD-----
MSMEG_2794|M.smegmatis_MC2_155 -LCGSELREVLQVRRCLEVEGARLAASNRTDADLAELRAFLDR-------
MMAR_0749|M.marinum_M YFAAARERDLWELREAVEVTAAVLSARRRDAADIEDLRALLARRNELWSR
MUL_1381|M.ulcerans_Agy99 YFAAARERDLWELREAVEVTAAVLSARRRDAADIEDLRVLLARRNELWSR
MAB_2272c|M.abscessus_ATCC_199 YFAAANNRDLIELRQTLEVTAAGLAAQRRDEDDIEQLRALLVRRNELWAP
Mb0601|M.bovis_AF2122/97 LLFRNGELDISVVRSILEARLRNFPKVAELAAERNEPELAELLQDSLR--
Rv0586|M.tuberculosis_H37Rv LLFRNGELDISVVRSILEARLRNFPKVAELAAERNEPELAELLQDSLR--
MAV_2560|M.avium_104 EYEGVTVKDVYDARVTLEVPMVEQLAKDRNPKVIAELEQIVERES-----
TH_2873|M.thermoresistible__bu EYEGVTVKDVYEARVALEVPMVVQLAKDRNPAVIAELERIVEAES-----
:: * :*. : .
Mvan_0952|M.vanbaalenii_PYR-1 ECAATDDTDAFARTDAEFHLAVVRGSGNRTLTELYRGLIEVVTASVA---
Mflv_0016|M.gilvum_PYR-GCK ERDSAGDVEAFARIDTEFHLAVVRCARNNTLIELYRGLLEAVTASVA---
MSMEG_2794|M.smegmatis_MC2_155 --TETSDDDDFVHSDTAFHLAVVRASHNSVLIELYRGLIEAITASVA---
MMAR_0749|M.marinum_M EPANDKERTEMTSADTALHRAIVAASHNEIYLQFYDLLLPTIHRAVE---
MUL_1381|M.ulcerans_Agy99 EPANDKERTEMTSADTALHRAIVAASHNETYLQFYDLLLPTIHRAVE---
MAB_2272c|M.abscessus_ATCC_199 HHVEPHNVEEAISTDIAVHRAVVAASHNALYLELYDSLLGLMDHYMR---
Mb0601|M.bovis_AF2122/97 ALDTEEDPIVWQRHTLDFWDHVVDSAGSIVDRLMYNAFRAAYEPTLAAL-
Rv0586|M.tuberculosis_H37Rv ALDTEEDPIVWQRHTLDFWDHVVDSAGSIVDRLMYNAFRAAYEPTLAAL-
MAV_2560|M.avium_104 ---QLNPGSEAVDQLTDFHAAIARLSGNSTLQIVSDMLHHIIEKANRSLQ
TH_2873|M.thermoresistible__bu ---KLEPGAETVSQLTDFHGAIARLSGNKTLQIVTDMLHHVIEKANRSLQ
. :. : . . :
Mvan_0952|M.vanbaalenii_PYR-1 ----TTRHVPVE--MVDHGVLVDQIAAGDAEQAARTAGELLDRILAGVDS
Mflv_0016|M.gilvum_PYR-GCK ----HTRHVPVD--VCDHGVLLDHIAAGDPDLAARTAGEFLDRIINGLGS
MSMEG_2794|M.smegmatis_MC2_155 ----TASARPDG--KVSHRGLVEAIAAGDVERAGREAGGFLDDLLAQTPD
MMAR_0749|M.marinum_M ----AGPVGTCTSYEREHTELVEAIIAGDPQRAEAAAQVFIARLRP----
MUL_1381|M.ulcerans_Agy99 ----AGPVGTCTSYEREHTELVEAIIAGDPQRAEAAAQVFIARLRR----
MAB_2272c|M.abscessus_ATCC_199 ----GNPIGAECSFEHEHTRLVESVIAGDIGGATSATEQLFAELRLSRDQ
Mb0601|M.bovis_AF2122/97 ----TTTMTAAAKRPSDYRKLADAICSGDPTGAKKAAQDLLELANTSLMA
Rv0586|M.tuberculosis_H37Rv ----TTTMTAAAKRPSDYRKLADAICSGDPTGAKKAAQDLLELANTSLMA
MAV_2560|M.avium_104 PTKGTRAEQAVRRSAKTHRMVLDMIKEGDAEKAGELWKRHLQKAEEFVLT
TH_2873|M.thermoresistible__bu PTEGTRAEQAVKKSTKTHRMVLDYIKAGDAEKAGELWQKHLQKAGEYLLS
. : : : : ** * :
Mvan_0952|M.vanbaalenii_PYR-1 ADSC--------
Mflv_0016|M.gilvum_PYR-GCK ADSS--------
MSMEG_2794|M.smegmatis_MC2_155 PQG---------
MMAR_0749|M.marinum_M ------------
MUL_1381|M.ulcerans_Agy99 ------------
MAB_2272c|M.abscessus_ATCC_199 PGRNFPHHPHD-
Mb0601|M.bovis_AF2122/97 VLVSQASRQ---
Rv0586|M.tuberculosis_H37Rv VLVSQASRQ---
MAV_2560|M.avium_104 GAELSTVVDLLE
TH_2873|M.thermoresistible__bu GTEMSTVVDLLE