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M. thermoresistible (build 8) TH_4408 (-)

annotation: regulatory protein GntR, HTH
coordinates: 3967374 - 3968126
length: 251

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_4408--100% (251)regulatory protein GntR, HTH
M. thermoresistible (build 8)TH_2873-e-11985.60% (250) PUTATIVE regulatory protein GntR, HTH
M. thermoresistible (build 8)TH_4024-4e-2430.24% (248) PUTATIVE transcriptional regulator, GntR family

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb3086c-1e-1930.32% (221) GntR family transcriptional regulator
M. gilvum PYR-GCKMflv_2114-1e-4040.00% (245) GntR domain-containing protein
M. tuberculosis H37RvRv3060c-1e-1930.32% (221) GntR family transcriptional regulator
M. leprae Br4923MLBr_01188-5e-0835.06% (77) hypothetical protein MLBr_01188
M. abscessus ATCC 19977MAB_4644c-9e-1128.12% (224) GntR family transcriptional regulator
M. marinum MMMAR_3975-3e-2734.31% (239) FadR family transcriptional regulator
M. avium 104MAV_1821-1e-11986.99% (246) regulatory protein GntR, HTH
M. smegmatis MC2 155MSMEG_5201-4e-3938.59% (241) regulatory protein GntR, HTH
M. ulcerans Agy99MUL_3832-3e-2734.31% (239) FadR family transcriptional regulator
M. vanbaalenii PYR-1Mvan_4590-7e-4039.83% (241) GntR domain-containing protein

CLUSTAL 2.0.9 multiple sequence alignment


TH_4408|M.thermoresistible__bu      ------------VEDYMEVTNLREPKMADRVATVLRRMFIRGEIPEGTML
MAV_1821|M.avium_104                ----------------MEVTSLREPKMADRVATVLRRMFIRGEIPEGTML
Mflv_2114|M.gilvum_PYR-GCK          MARSTPLAPMIGPDAVASRTAVRSPKTAELVAGTLRRMVVEGQLKDGDFL
Mvan_4590|M.vanbaalenii_PYR-1       MTRNTPLAPMIGPDAVASRAAVRSPKTAELVAGTLRRMVVEGQLKDGDFL
MSMEG_5201|M.smegmatis_MC2_155      MAGSTPLAPMIGPDAITPRAAVRSPKTAELVAGTLRRMVVEGQLKDGDFL
MMAR_3975|M.marinum_M               --------MTALGIGPDPRRRLSAPRIAEIVADELRRQIIDGELADGDLL
MUL_3832|M.ulcerans_Agy99           --------MTALGIGPDPRRRLSAPRIAEIVADELRRQIIDGELADGDLL
MLBr_01188|M.leprae_Br4923          -------------------------------------------------M
Mb3086c|M.bovis_AF2122/97           --------------MSTEPDAVWTDKRASKIARRIEADIVRRGWPIGASL
Rv3060c|M.tuberculosis_H37Rv        --------------MSTEPDAVWTDKRASKIARRIEADIVRRGWPIGASL
MAB_4644c|M.abscessus_ATCC_199      -----------------MHPRLSSQSLAEQVANILAAQIGDGRWSTGAKL
                                                                                     :

TH_4408|M.thermoresistible__bu      PPESELMERFGVSRPTLREAFRVLESESLIVIQRGVRGGARVTRPRRETL
MAV_1821|M.avium_104                PPESELMERFGVSRPTLREAFRVLESESLIVVQRGVRGGARVTRPRRETL
Mflv_2114|M.gilvum_PYR-GCK          PNEAELMAHFGVSRPTLREAVRVLESERLVEVRRGSRTGARVRVPGPEIV
Mvan_4590|M.vanbaalenii_PYR-1       PNEAELMAHFGVSRPTLREAVRVLESERLVEVRRGSRTGARVRVPGPEIV
MSMEG_5201|M.smegmatis_MC2_155      PNEAELMSHFGVSRPTLREAVRVLESERLVEVRRGSRTGARVRVPGPEIV
MMAR_3975|M.marinum_M               PRQEVLVEQFNVSLVSLREALRILETEGLVSVRRGNRGGAVVHAPAKTSA
MUL_3832|M.ulcerans_Agy99           PRQEVLVEQFNVSLVSLREALRILETEGLVSVRRGNRGGAVVHAPAKASA
MLBr_01188|M.leprae_Br4923          PRQEALVEPLNVSLLSFREALQIMDTERLISLRRGNRGSVVVHTPTRTSA
Mb3086c|M.bovis_AF2122/97           GSESALQQRFCVSRSVLREAVRLVEHHQVARMRRGPNGGLFICEPNAGPA
Rv3060c|M.tuberculosis_H37Rv        GSESALQQRFCVSRSVLREAVRLVEHHQVARMRRGPNGGLFICEPNAGPA
MAB_4644c|M.abscessus_ATCC_199      PGEVALCEEFGVSRATVREAIRDLKTKGLVSTRQG--AGVFVTSDRP---
                                      :  *   : **   .***.: :. . :   ::*   .  :        

TH_4408|M.thermoresistible__bu      ARYAGLILEYEEVTLKDVYEARMTIEMPMVVELAK--KRDPAVIAELEAI
MAV_1821|M.avium_104                ARYAGLILEYEGVTLKDVYDARVTLETPMIVQLAK--DRNPAVIAELEQI
Mflv_2114|M.gilvum_PYR-GCK          ARPAGLLLELSGATIADLLTAKSAIEPMAARLLAE--SGSAAAFDELEQL
Mvan_4590|M.vanbaalenii_PYR-1       ARPAGLLLELSGATIADLLTAKSGIEPMAARLLAE--SGSPEAFDELERM
MSMEG_5201|M.smegmatis_MC2_155      ARPVGLLLELSGADIADLLVARSAIEPMAARLLAE--NGTEEQFAELDRM
MMAR_3975|M.marinum_M               AYMLGLLLQSESVAVSDLGAALQELEPACAALAAQRPDRADTLVPELKRV
MUL_3832|M.ulcerans_Agy99           AYMLGLLLQSESVAVSDLGAALQELEPACAALAAQRPDRADTLVPELKRV
MLBr_01188|M.leprae_Br4923          AYMLGLLLQSKSIALADLGAALQELEPACAALAAQ---------------
Mb3086c|M.bovis_AF2122/97           TRAVVIYLEYLGTTIGDLLGARLVLEPLAASLAAEHIDEPG-----IERL
Rv3060c|M.tuberculosis_H37Rv        TRAVVIYLEYLGTTIGDLLGARLVLEPLAASLAAEHIDEPG-----IERL
MAB_4644c|M.abscessus_ATCC_199      --LGQWDRVLAAAEIDAVVEIRRLLEVQAAGLAAERRNRSDVAAIRRALV
                                                  :  :      :*       *:               

TH_4408|M.thermoresistible__bu      VANESNLKPGSETVDQLT-DFHAAVARLSGNKTLQIVADMLHHIVKTANR
MAV_1821|M.avium_104                VEREAELKPGSDTVDQLT-DFHAAIARLSGSKTLQIVSDMLHHIVEKANR
Mflv_2114|M.gilvum_PYR-GCK          LEELVADSHQSPRLAEATGAFHLRVVQLSGNATLSIVAGMLHEITVRHTA
Mvan_4590|M.vanbaalenii_PYR-1       LEELAADSHKSSRLAEATGLFHLRVVQLSGNATLSIVAGMLHEITVRHTA
MSMEG_5201|M.smegmatis_MC2_155      LEEHIPSDWQSDRLAETTGDFHRRVVELSGNATLGIIAGMLHEITVRHHQ
MMAR_3975|M.marinum_M               NEAMSEHLDDGAMFTEIGRQFHDLIVRGCGNHTIIAVVGSLETLWTSHEQ
MUL_3832|M.ulcerans_Agy99           NEAMSEHLDDGAMFTEIGRQFHDLIVRGCGNHTIIAVVGSLETLWTSHEQ
MLBr_01188|M.leprae_Br4923          --------------------------------------------------
Mb3086c|M.bovis_AF2122/97           RAVLRAEERWRPGLPPPPEQFYRVLAEQSKNPVLQLFIDILMRLTKRYVQ
Rv3060c|M.tuberculosis_H37Rv        RAVLRAEERWRPGLPPPPEQFYRVLAEQSKNPVLQLFIDILMRLTKRYVQ
MAB_4644c|M.abscessus_ATCC_199      ARAKAESAGDDIEYVDADLEFHRAVVAAVHNPLLDELFDSFSVRMREAML
                                                                                      

TH_4408|M.thermoresistible__bu      SLQPTEGTRAEQ----AVRRSAKTHRMVLELIKAGDAEKAGELWQRHLQK
MAV_1821|M.avium_104                SLQPTEGTRAAQ----AVSRSAKTHRMVLDMIKAGEAEKAGELWKKHLQK
Mflv_2114|M.gilvum_PYR-GCK          FVFNERRPVSKA----DYETLLRSYRRLLQFLRSRDADGAEAHWRRHLDK
Mvan_4590|M.vanbaalenii_PYR-1       FVFNERRPVSKA----DYDTLLRSYRKLMQFLRAGDAVGAEAHWRKHLDT
MSMEG_5201|M.smegmatis_MC2_155      FLFREHRPVSKS----DYDKLMRSYRKLMQIMRSGDGDAAEAHWRTHLDT
MMAR_3975|M.marinum_M               QWADESAARGTYPSLTKRRAVLNTHIKLTETIAEGDVDRARRIAGRHLAD
MUL_3832|M.ulcerans_Agy99           QWADESAARGTYPSLAKRRAVLNAHIKLTETIAEGDVDRARRIAGRHLAD
MLBr_01188|M.leprae_Br4923          --------------------------------------------------
Mb3086c|M.bovis_AF2122/97           KSGTQSAGEAVE----AAGQVHNEHSDIVAAVTAGDSAWAKTLSERHVEA
Rv3060c|M.tuberculosis_H37Rv        KSGTQSAGEAVE----AAGQVHNEHSDIVAAVTAGDSAWAKTLSERHVEA
MAB_4644c|M.abscessus_ATCC_199      ALLAGSAERPHD---------QEHHQWLFDAIVDGSTRRAVELATDQLQH
                                                                                      

TH_4408|M.thermoresistible__bu      AEEFVLSGAEMSTVVDLLE-------------------------------
MAV_1821|M.avium_104                AEAFVLSGAELSTVVDLLE-------------------------------
Mflv_2114|M.gilvum_PYR-GCK          TRELLLAGLESVPVRDVMG-------------------------------
Mvan_4590|M.vanbaalenii_PYR-1       TRELLLTGLESVPVRDVMG-------------------------------
MSMEG_5201|M.smegmatis_MC2_155      ARALMLQGLESVKVRDVMG-------------------------------
MMAR_3975|M.marinum_M               TQTYVLSGRAEQRIYALSPQALSRPRDMRRP-------------------
MUL_3832|M.ulcerans_Agy99           TQTYVLSGRAEQRIYALSPQALSRPRDMRRP-------------------
MLBr_01188|M.leprae_Br4923          --------------------------------------------------
Mb3086c|M.bovis_AF2122/97           VAGWLQQHQRGNDAAVRNGGRAREPRRAQQLILGAPRGKLAEVLAATIGD
Rv3060c|M.tuberculosis_H37Rv        VAGWLQQHQRGNDAAVRNGGRAREPRRAQQLILGAPRGKLAEVLAATIGD
MAB_4644c|M.abscessus_ATCC_199      VRMR----------------------------------------------
                                                                                      

TH_4408|M.thermoresistible__bu      --------------------------------------------------
MAV_1821|M.avium_104                --------------------------------------------------
Mflv_2114|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_4590|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_5201|M.smegmatis_MC2_155      --------------------------------------------------
MMAR_3975|M.marinum_M               --------------------------------------------------
MUL_3832|M.ulcerans_Agy99           --------------------------------------------------
MLBr_01188|M.leprae_Br4923          --------------------------------------------------
Mb3086c|M.bovis_AF2122/97           DIAASGWQVGSVFGTETALLERYQVSRAVLREAVRLLEYHAIAHMRRGPG
Rv3060c|M.tuberculosis_H37Rv        DIAASGWQVGSVFGTETALLERYQVSRAVLREAVRLLEYHAIAHMRRGPG
MAB_4644c|M.abscessus_ATCC_199      --------------------------------------------------
                                                                                      

TH_4408|M.thermoresistible__bu      --------------------------------------------------
MAV_1821|M.avium_104                --------------------------------------------------
Mflv_2114|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_4590|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_5201|M.smegmatis_MC2_155      --------------------------------------------------
MMAR_3975|M.marinum_M               --------------------------------------------------
MUL_3832|M.ulcerans_Agy99           --------------------------------------------------
MLBr_01188|M.leprae_Br4923          --------------------------------------------------
Mb3086c|M.bovis_AF2122/97           GGLVVTTPQPQASIDTIALYLQYRKPSREDLRCVRDAIEIDNVAKVVKRR
Rv3060c|M.tuberculosis_H37Rv        GGLVVTTPQPQASIDTIALYLQYRKPSREDLRCVRDAIEIDNVAKVVKRR
MAB_4644c|M.abscessus_ATCC_199      --------------------------------------------------
                                                                                      

TH_4408|M.thermoresistible__bu      --------------------------------------------------
MAV_1821|M.avium_104                --------------------------------------------------
Mflv_2114|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_4590|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_5201|M.smegmatis_MC2_155      --------------------------------------------------
MMAR_3975|M.marinum_M               --------------------------------------------------
MUL_3832|M.ulcerans_Agy99           --------------------------------------------------
MLBr_01188|M.leprae_Br4923          --------------------------------------------------
Mb3086c|M.bovis_AF2122/97           SEPEVASFLDTLGRPRLDNPTDDVRAAAVEEFRFHVGLARAAGNTMLDLF
Rv3060c|M.tuberculosis_H37Rv        SEPEVASFLDTLGRPRLDNPTDDVRAAAVEEFRFHVGLARAAGNTMLDLF
MAB_4644c|M.abscessus_ATCC_199      --------------------------------------------------
                                                                                      

TH_4408|M.thermoresistible__bu      --------------------------------------------------
MAV_1821|M.avium_104                --------------------------------------------------
Mflv_2114|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_4590|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_5201|M.smegmatis_MC2_155      --------------------------------------------------
MMAR_3975|M.marinum_M               --------------------------------------------------
MUL_3832|M.ulcerans_Agy99           --------------------------------------------------
MLBr_01188|M.leprae_Br4923          --------------------------------------------------
Mb3086c|M.bovis_AF2122/97           LLILVELFRRHLSSTEQALPTWSDVVAVGHAHVRILEAIGSGDDSLARCR
Rv3060c|M.tuberculosis_H37Rv        LLILVELFRRHLSSTEQALPTWSDVVAVGHAHVRILEAIGSGDDSLARCR
MAB_4644c|M.abscessus_ATCC_199      --------------------------------------------------
                                                                                      

TH_4408|M.thermoresistible__bu      -------------
MAV_1821|M.avium_104                -------------
Mflv_2114|M.gilvum_PYR-GCK          -------------
Mvan_4590|M.vanbaalenii_PYR-1       -------------
MSMEG_5201|M.smegmatis_MC2_155      -------------
MMAR_3975|M.marinum_M               -------------
MUL_3832|M.ulcerans_Agy99           -------------
MLBr_01188|M.leprae_Br4923          -------------
Mb3086c|M.bovis_AF2122/97           TRRHLDAAASWWL
Rv3060c|M.tuberculosis_H37Rv        TRRHLDAAASWWL
MAB_4644c|M.abscessus_ATCC_199      -------------