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M. thermoresistible (build 8) TH_4055 (-)

annotation: two component transcriptional regulator, winged helix family
coordinates: 3736663 - 3737328
length: 222

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_4055--100% (222)two component transcriptional regulator, winged helix family
M. thermoresistible (build 8)TH_1732phoP8e-4944.25% (226) DNA-binding response regulator PhoP
M. thermoresistible (build 8)TH_4543-1e-4545.21% (219) PUTATIVE two component transcriptional regulator, winged helix

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb1007mprA2e-4743.36% (226) two component response transcriptional regulatory protein
M. gilvum PYR-GCKMflv_3998-2e-8066.97% (218) two component transcriptional regulator
M. tuberculosis H37RvRv0981mprA3e-4743.36% (226) two component response transcriptional regulatory protein
M. leprae Br4923MLBr_00174-3e-4742.92% (226) putative two-component response regulator
M. abscessus ATCC 19977MAB_1076-7e-5044.69% (226) two component response transcriptional regulatory protein MprA
M. marinum MMMAR_4529mprA2e-4743.86% (228) two component response transcriptional regulatory protein
M. avium 104MAV_1094-5e-4843.81% (226) two component response transcriptional regulatory protein MprA
M. smegmatis MC2 155MSMEG_5488-7e-4742.04% (226) DNA-binding response regulator
M. ulcerans Agy99MUL_4701mprA5e-4842.98% (228) two component response transcriptional regulatory protein
M. vanbaalenii PYR-1Mvan_2389-2e-8168.18% (220) two component transcriptional regulator

CLUSTAL 2.0.9 multiple sequence alignment


Mb1007|M.bovis_AF2122/97            MSVRILVVDDDRAVRESLRRSLSFNGYSVELAHDGVEALDMIASDRPDAL
Rv0981|M.tuberculosis_H37Rv         MSVRILVVDDDRAVRESLRRSLSFNGYSVELAHDGVEALDMIASDRPDAL
MAV_1094|M.avium_104                --MRILVVDDDRAVRESLRRSLSFNGYSVELAHDGVEALDMIASDRPDAL
MMAR_4529|M.marinum_M               MSVRILVVDDDRAVRESLRRSLSFNGYTVELAHDGVEALEMIASDRPDAL
MUL_4701|M.ulcerans_Agy99           MSVRILVVDDDRAVRESLRRSLSFNGYTVELAHDGVEALEMIASDRPDAL
MLBr_00174|M.leprae_Br4923          --MRILAVDDDRAVRESLRRSLSFNGYSVELANDGVEALEMVARDRPDAL
MSMEG_5488|M.smegmatis_MC2_155      MAVRILVVDDDRAVRESLRRSLSFNGYSVELAQDGVEALDAITNNRPDAL
MAB_1076|M.abscessus_ATCC_1997      MPVRILVVDDDRAVRESLRRSLSFNGYSVDLAEDGVDALNVIANDRPDAL
Mflv_3998|M.gilvum_PYR-GCK          -MAAVLIAEDEPRISALVRKGLSANGFSVTVVPDGPSAYAYAHSGAFDLM
Mvan_2389|M.vanbaalenii_PYR-1       -MTAILIAEDEPRVSSFVRKGLSSNGYSVTLVTDGRSAYFSARNGGFDLM
TH_4055|M.thermoresistible__bu      -MARILIVEDEPRISSFIEKGLSANGFTATTVTDGPTGYDYAMTGGFDLM
                                        :* .:*:  :   :.:.** **::.  . **  .      .  * :

Mb1007|M.bovis_AF2122/97            VLDVMMPRLDGLEVCRQLRSTGDDLPILVLTARDSVSERVAGLDAGADDY
Rv0981|M.tuberculosis_H37Rv         VLDVMMPRLDGLEVCRQLRGTGDDLPILVLTARDSVSERVAGLDAGADDY
MAV_1094|M.avium_104                VLDVMMPRLDGLEVCRQLRSTGDDLPILVLTARDSVSERVAGLDAGADDY
MMAR_4529|M.marinum_M               VLDVMMPRLDGLEVCRQLRSTGDDLPILVLTARDSVSERVAGLDAGADDY
MUL_4701|M.ulcerans_Agy99           VLDVMMPRLDGLEVCRQLRSTGDDLPILVLTARDSVSERVAGLDAGADDY
MLBr_00174|M.leprae_Br4923          VLDVMMPRLDGLEVCRQLRSTGDDLPILVLTARDSVSERVAGLDAGADDY
MSMEG_5488|M.smegmatis_MC2_155      ILDVMMPRLDGLEVCRQLRSTGDDLPILVLTARDSVSERVAGLDAGADDY
MAB_1076|M.abscessus_ATCC_1997      VLDVMMPKLDGLEVCRRLRSTGDDLPILVLTARDSVSERVAGLDAGADDY
Mflv_3998|M.gilvum_PYR-GCK          VLDTGLPGMDGLSVLRRLRAEGSALPVIVLTTRTTGADT-AALLGGADDV
Mvan_2389|M.vanbaalenii_PYR-1       LLDTDLPGMDGFAVLRRLRADGSPLPVVMLMSRAGVADTTAALEEGADDY
TH_4055|M.thermoresistible__bu      VLDIGLPSMDGFTVLRKLREDGNQIPVIVLTARDSVEDTVAGLEGGADDY
                                    :**  :* :**: * *:**  *. :*:::* :*    :  *.*  **** 

Mb1007|M.bovis_AF2122/97            LPKPFALEELLARMRALLRRTKPED--AAESMAMRFSDLTLDPVTREVNR
Rv0981|M.tuberculosis_H37Rv         LPKPFALEELLARMRALLRRTKPED--AAESMAMRFSDLTLDPVTREVNR
MAV_1094|M.avium_104                LPKPFALEELLARMRALLRRTKPED--DAESVAMTFSDLTLDPVTREVTR
MMAR_4529|M.marinum_M               LPKPFALEELLARMRALLRRTKPEDDEAADSVAMTFSDLSLDPVTREVTR
MUL_4701|M.ulcerans_Agy99           LPKPFALEELLARMRALLRRTKLEDDEAADSVAMTFSDLSLDPVTREVTR
MLBr_00174|M.leprae_Br4923          LPKPFALEELLARIRALLRRTKPDD--AAESVAMSFSDLTLDPVTREVAR
MSMEG_5488|M.smegmatis_MC2_155      LPKPFALEELLARMRALLRRTVSDD--SGDSQKMTFSDLTLDPVTREVTR
MAB_1076|M.abscessus_ATCC_1997      LPKPFALEELLARMRALLRRTTIDE--SADAATLSFGDLTLDPVTREVHR
Mflv_3998|M.gilvum_PYR-GCK          IAKPFRLEDLVSRVRTRLS---PGR--AARTHTLSYGNLRLDLRTRRAHV
Mvan_2389|M.vanbaalenii_PYR-1       VVKPFRFEDLLARVRLRLT---AGR--AAST-TLAYGSLLLDLRTRRAHV
TH_4055|M.thermoresistible__bu      MPKPFRFEELLARIRLRLT---TER--SAELTVLTCGGMQLDLRTRRAKV
                                    : *** :*:*::*:*  *          .    :  ..: **  **..  

Mb1007|M.bovis_AF2122/97            GQRRISLTRTEFALLEMLIANPRRVLTRSRILEEVWGFDFPTSGNALEVY
Rv0981|M.tuberculosis_H37Rv         GQRRISLTRTEFALLEMLIANPRRVLTRSRILEEVWGFDFPTSGNALEVY
MAV_1094|M.avium_104                GQRRISLTRTEFALLEMLIANPRRVLTRSRILEEVWGFDFPTSGNALEVY
MMAR_4529|M.marinum_M               GARRISLTRTEFALLEMLIANPRRVLTRSRILEEVWGFDFPTSGNALEVY
MUL_4701|M.ulcerans_Agy99           GARRISLTRTEFALLEMLIANPRRVLTRSRILEEVWGFDFPTSGNALEVY
MLBr_00174|M.leprae_Br4923          GQRWISLTRTEFALLEMLIANPRRVLTRSRILEEVWGFDFPTSGNALEVY
MSMEG_5488|M.smegmatis_MC2_155      GGRQISLTRTEFSLLEMLIANPRRVLTRSRILEEVWGFDFPTSGNALEVY
MAB_1076|M.abscessus_ATCC_1997      GTRSISLTRTEFALLEMLMANPRRVLTRSRILEEVWGFDFPTSGNALEVY
Mflv_3998|M.gilvum_PYR-GCK          GDYSVDLSAREFALAEMFLRHPGQVLTRDQLLRQVWGNDYEPGSNVVDVY
Mvan_2389|M.vanbaalenii_PYR-1       GDYAVDLSARECKLAETFLRHPGQVLSREQLLNQVWGRDHETGSNVVDVY
TH_4055|M.thermoresistible__bu      GDKTVDLSAREFALAETFMRHPGQVLSREQLLSRVWGYDFDPGSNVVDVY
                                    *   :.*:  *  * * :: :* :**:*.::* .*** *. ...*.::**

Mb1007|M.bovis_AF2122/97            VGYLRRKTEADGEPRLIHTVRGVGYVLRETPP
Rv0981|M.tuberculosis_H37Rv         VGYLRRKTEADGEPRLIHTVRGVGYVLRETPP
MAV_1094|M.avium_104                VGYLRRKTEADGEPRLIHTVRGVGYVLRETPP
MMAR_4529|M.marinum_M               VGYLRRKTEAEGEPRLIHTVRGVGYVLRETPP
MUL_4701|M.ulcerans_Agy99           VGYLRRKTEAEGEPRLIHTVRGVGYVLRETPP
MLBr_00174|M.leprae_Br4923          VGYLRRKTEADGESRLIHTVRGVGYVLRETPP
MSMEG_5488|M.smegmatis_MC2_155      IGYLRRKTEAEGEPRLIHTVRGVGYVLRETPP
MAB_1076|M.abscessus_ATCC_1997      VGYLRRKTEAEGELRLIHTVRGVGYVLRETPP
Mflv_3998|M.gilvum_PYR-GCK          VRYLRRKLGARR----FVTLRGMGYRLEAVH-
Mvan_2389|M.vanbaalenii_PYR-1       VRYLRRKLGANR----FATLRGMGYRLEPI--
TH_4055|M.thermoresistible__bu      VRYLRRKLGAER----FVTVRGMGYRLEELP-
                                    : *****  *      : *:**:** *.