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M. thermoresistible (build 8) TH_4543 (-)

annotation: two component transcriptional regulator, winged helix family
coordinates: 984707 - 985375
length: 223

aa seq not available

Operon Prediction Model: Genebank

Paralogs

species id gene e-value identity (len) annotation
M. thermoresistible (build 8) TH_4543 - - 100% (223) two component transcriptional regulator, winged helix family
M. thermoresistible (build 8) TH_1732 phoP 1e-57 51.36% (220) DNA-binding response regulator PhoP
M. thermoresistible (build 8) TH_4055 - 1e-45 45.21% (219) PUTATIVE two component transcriptional regulator, winged helix

Closest Orthologs (e-value cutoff: 1e-4)

species id gene e-value identity (len) annotation
M. bovis AF2122 / 97 Mb0927c prrA 1e-114 95.95% (222) two component response transcriptional regulatory protein
M. gilvum PYR-GCK Mflv_1744 - 1e-115 95.95% (222) two component transcriptional regulator
M. tuberculosis H37Rv Rv0903c prrA 1e-114 95.95% (222) two component response transcriptional regulatory protein
M. leprae Br4923 MLBr_02123 - 1e-114 94.59% (222) two-component response regulator
M. abscessus ATCC 19977 MAB_0956c - 1e-111 92.34% (222) transcriptional regulatory protein PrrA
M. marinum M MMAR_4633 prrA 1e-115 96.40% (222) two-component response transcriptional regulatory protein
M. avium 104 MAV_1022 - 1e-115 96.40% (222) two component response transcriptional regulatory protein prra
M. smegmatis MC2 155 MSMEG_5662 prrA 1e-116 97.75% (222) DNA-binding response regulator PrrA
M. ulcerans Agy99 MUL_0248 prrA 1e-114 96.36% (220) two component response transcriptional regulatory protein
M. vanbaalenii PYR-1 Mvan_5009 - 1e-114 95.95% (222) two component transcriptional regulator

CLUSTAL 2.0.9 multiple sequence alignment


TH_4543|M.thermoresistible__bu      -----------------VVDDDPDVLASLERGLRLSGFEVSTAVDGAEAL
MSMEG_5662|M.smegmatis_MC2_155      ---MDSTTSGMASPRVLVVDDDPDVLASLERGLRLSGFDVSTAVDGAEAL
Mflv_1744|M.gilvum_PYR-GCK          ---MDS-----GSPRVLVVDDDPDVLASLERGLRLSGFDVFTAVDGAEAL
Mvan_5009|M.vanbaalenii_PYR-1       ---MDSGA---GSPKVLVVDDDPDVLASLERGLRLSGFDVYTAVDGAEAL
MMAR_4633|M.marinum_M               MGGMDTGAN---SPRVLVVDDDSDVLASLERGLRLSGFEVSTAVDGAEAL
MUL_0248|M.ulcerans_Agy99           MGGMDTGAN---SPRVLVVDDDSDVLASLERGLRLSGFEVSTAVDGAEAL
MAV_1022|M.avium_104                ---MDTAAS---SPRVLVVDDDSDVLASLERGLRLSGFEVSTAVDGAEAL
MLBr_02123|M.leprae_Br4923          ---MDTGVS---SPRVLVVDDDSDVLASLERGLRLSGFEVSTAIDGAEAL
Mb0927c|M.bovis_AF2122/97           MGGMDTGVT---SPRVLVVDDDSDVLASLERGLRLSGFEVATAVDGAEAL
Rv0903c|M.tuberculosis_H37Rv        MGGMDTGVT---SPRVLVVDDDSDVLASLERGLRLSGFEVATAVDGAEAL
MAB_0956c|M.abscessus_ATCC_199      ---MVDGQG---SPRVLVVDDDADVLASLERGLRLSGFEVNTASDGAEAL
                                                     *****.***************:* ** ******

TH_4543|M.thermoresistible__bu      RSATETRPDAIVLDINMPVLDGVSVVTALRAMDNDVPVCVLSARSSVDDR
MSMEG_5662|M.smegmatis_MC2_155      RSATETRPDAIVLDINMPVLDGVSVVTALRAMDNDVPVCVLSARSSVDDR
Mflv_1744|M.gilvum_PYR-GCK          RSATETRPDAIVLDINMPVLDGVSVVTALRAMDNDVPVCVLSARSSVDDR
Mvan_5009|M.vanbaalenii_PYR-1       RSATETRPDAIVLDINMPVLDGVSVVTALRAMDNDVPVCVLSARSSVDDR
MMAR_4633|M.marinum_M               RSATETRPDAIVLDINMPVLDGVSVVTALRAMDNDVPVCVLSARSSVDDR
MUL_0248|M.ulcerans_Agy99           RSATETRPDAIVLDINMPVLDGVSVVTALRAMDNDVPVCVLSARSSVDDR
MAV_1022|M.avium_104                RSATETRPDAIVLDINMPVLDGVSVVTALRAMDNDVPVCVLSARSSVDDR
MLBr_02123|M.leprae_Br4923          RNATETRPDAIVLDINMPVLDGVSVVTALRAMDNDVPVCVLSARSSVDDR
Mb0927c|M.bovis_AF2122/97           RSATENRPDAIVLDINMPVLDGVSVVTALRAMDNDVPVCVLSARSSVDDR
Rv0903c|M.tuberculosis_H37Rv        RSATENRPDAIVLDINMPVLDGVSVVTALRAMDNDVPVCVLSARSSVDDR
MAB_0956c|M.abscessus_ATCC_199      RCATEHRPDAIVLDINMPVLDGVSVVTALRAMDNDVPVCVLSARTSVDDR
                                    * *** **************************************:*****

TH_4543|M.thermoresistible__bu      VAGLEAGADDYLVKPFVLAELVARVKALLRRRGSSATSSSETIVVGPLEV
MSMEG_5662|M.smegmatis_MC2_155      VAGLEAGADDYLVKPFVLAELVARVKALLRRRGSSATFSSETIQVGPLEV
Mflv_1744|M.gilvum_PYR-GCK          VAGLEAGADDYLVKPFVLAELVARVKALLRRRGSTATFSSETITVGPLEV
Mvan_5009|M.vanbaalenii_PYR-1       VAGLEAGADDYLVKPFVLAELVARVKALLRRRGSTATFSSETITVGPLEV
MMAR_4633|M.marinum_M               VAGLEAGADDYLVKPFVLAELVARVKALLRRRGATATSSSETITVGPLEV
MUL_0248|M.ulcerans_Agy99           VAGLEAGADDYLVKPFVLAELVARVKALLRRRGATATSSSEIITVGPLEV
MAV_1022|M.avium_104                VAGLEAGADDYLVKPFVLAELVARVKALLRRRGATATSSSETITVGPLEV
MLBr_02123|M.leprae_Br4923          VAGLEAGADDYLVKPFVLAELVARVKALLRRRGATATSSSETIAVGPLEV
Mb0927c|M.bovis_AF2122/97           VAGLEAGADDYLVKPFVLAELVARVKALLRRRGSTATSSSETITVGPLEV
Rv0903c|M.tuberculosis_H37Rv        VAGLEAGADDYLVKPFVLAELVARVKALLRRRGSTATSSSETITVGPLEV
MAB_0956c|M.abscessus_ATCC_199      VAGLEAGADDYLTKPFVLAELVARVKALLRRRGAVATSSTETITVGPLEV
                                    ************.********************: ** *:* * ******

TH_4543|M.thermoresistible__bu      DIPGRRARVNGQDVDLTKREFDLLAVLAEHKTAVLSRAQLLELVWGYDFA
MSMEG_5662|M.smegmatis_MC2_155      DIPGRRARVNGVDVDLTKREFDLLAVLAEHKTAVLSRAQLLELVWGYDFA
Mflv_1744|M.gilvum_PYR-GCK          DIPGRRARVDGVDVDLTKREFDLLAVLAEHKTAVLSRAQLLELVWGYDFA
Mvan_5009|M.vanbaalenii_PYR-1       DIPGRRARVDGVDVDLTKREFDLLAVLAEHKTAVLSRAQLLELVWGYDFA
MMAR_4633|M.marinum_M               DIPGRRARVNGVDVDLTKREFDLLAVLAEHKTAVLSRAQLLELVWGYDFA
MUL_0248|M.ulcerans_Agy99           DIPGRRARVNGVDVDLTKREFDLLAVLAEHKTAVLSRAQLLELVWGYDFA
MAV_1022|M.avium_104                DIPGRRARVNGVDVDLTKREFDLLAVLAEHKTAVLSRAQLLELVWGYDFA
MLBr_02123|M.leprae_Br4923          DIPGRRARVNGVDVDLTKREFDLLAVLAEHKTTVLSRAQLLELVWGYDFA
Mb0927c|M.bovis_AF2122/97           DIPGRRARVNGVDVDLTKREFDLLAVLAEHKTAVLSRAQLLELVWGYDFA
Rv0903c|M.tuberculosis_H37Rv        DIPGRRARVNGVDVDLTKREFDLLAVLAEHKTAVLSRAQLLELVWGYDFA
MAB_0956c|M.abscessus_ATCC_199      EIPGRRARINGVEVDLTKREFDLLAVLAEHKTAVLSRAQLLELVWGYDFA
                                    :*******::* :*******************:*****************

TH_4543|M.thermoresistible__bu      ADTNVVDVFIGYLRRKLEATGAPRLLHTVRGVGFVLRTQ
MSMEG_5662|M.smegmatis_MC2_155      ADTNVVDVFIGYLRRKLEAGGAPRLLHTVRGVGFVLRTQ
Mflv_1744|M.gilvum_PYR-GCK          ADTNVVDVFIGYLRRKLEANGAPRLLHTVRGVGFVLRQQ
Mvan_5009|M.vanbaalenii_PYR-1       ADTNVVDVFIGYLRRKLEANGAPRLLHTVRGVGFVLRQQ
MMAR_4633|M.marinum_M               ADTNVVDVFIGYLRRKLEANGGPRLLHTVRGVGFVLRMQ
MUL_0248|M.ulcerans_Agy99           ADTNVVDVFIGYLRRKLEANGGPRLLHTVRGVGFVLRMH
MAV_1022|M.avium_104                ADTNVVDVFIGYLRRKLEANGGPRLLHTVRGVGFVLRMQ
MLBr_02123|M.leprae_Br4923          ADTNVVDVFIGYLRRKLEANSGPRLLHTVRGVGFVLRMQ
Mb0927c|M.bovis_AF2122/97           ADTNVVDVFIGYLRRKLEAGGGPRLLHTVRGVGFVLRMQ
Rv0903c|M.tuberculosis_H37Rv        ADTNVVDVFIGYLRRKLEAGGGPRLLHTVRGVGFVLRMQ
MAB_0956c|M.abscessus_ATCC_199      ADTNVVDVFIGYLRRKLEAGGAPRLLHTVRGVGFVLRSQ
                                    ******************* ..*************** :

species	id	gene	e-value	identity (len)	annotation
M. thermoresistible (build 8)	TH_4543	-	-	100% (223)	two component transcriptional regulator, winged helix family
M. thermoresistible (build 8)	TH_1732	phoP	1e-57	51.36% (220)	DNA-binding response regulator PhoP
M. thermoresistible (build 8)	TH_4055	-	1e-45	45.21% (219)	PUTATIVE two component transcriptional regulator, winged helix