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M. thermoresistible (build 8) TH_1732 (phoP)

annotation: DNA-binding response regulator PhoP
coordinates: 3326436 - 3327128
length: 231

aa seq not available

Operon Prediction Model: Genebank

Paralogs

species id gene e-value identity (len) annotation
M. thermoresistible (build 8) TH_1732 phoP - 100% (231) DNA-binding response regulator PhoP
M. thermoresistible (build 8) TH_4543 - 1e-57 51.36% (220) PUTATIVE two component transcriptional regulator, winged helix
M. thermoresistible (build 8) TH_4055 - 9e-49 44.25% (226) PUTATIVE two component transcriptional regulator, winged helix

Closest Orthologs (e-value cutoff: 1e-4)

species id gene e-value identity (len) annotation
M. bovis AF2122 / 97 Mb1007 mprA 1e-117 90.87% (230) two component response transcriptional regulatory protein
M. gilvum PYR-GCK Mflv_1887 - 1e-115 90.91% (231) two component transcriptional regulator
M. tuberculosis H37Rv Rv0981 mprA 1e-117 90.43% (230) two component response transcriptional regulatory protein
M. leprae Br4923 MLBr_00174 - 1e-115 89.91% (228) putative two-component response regulator
M. abscessus ATCC 19977 MAB_1076 - 1e-114 89.13% (230) two component response transcriptional regulatory protein MprA
M. marinum M MMAR_4529 mprA 1e-116 90.09% (232) two component response transcriptional regulatory protein
M. avium 104 MAV_1094 - 1e-117 91.67% (228) two component response transcriptional regulatory protein MprA
M. smegmatis MC2 155 MSMEG_5488 - 1e-119 92.61% (230) DNA-binding response regulator
M. ulcerans Agy99 MUL_4701 mprA 1e-115 89.66% (232) two component response transcriptional regulatory protein
M. vanbaalenii PYR-1 Mvan_4844 - 1e-117 91.77% (231) two component transcriptional regulator

CLUSTAL 2.0.9 multiple sequence alignment


TH_1732|M.thermoresistible__bu      VAVRILVVDDDRAVRESLRRSLSFNGYSVELAEDGVEALDLIANDRPDAV
MSMEG_5488|M.smegmatis_MC2_155      MAVRILVVDDDRAVRESLRRSLSFNGYSVELAQDGVEALDAITNNRPDAL
Mb1007|M.bovis_AF2122/97            MSVRILVVDDDRAVRESLRRSLSFNGYSVELAHDGVEALDMIASDRPDAL
Rv0981|M.tuberculosis_H37Rv         MSVRILVVDDDRAVRESLRRSLSFNGYSVELAHDGVEALDMIASDRPDAL
MAV_1094|M.avium_104                --MRILVVDDDRAVRESLRRSLSFNGYSVELAHDGVEALDMIASDRPDAL
MLBr_00174|M.leprae_Br4923          --MRILAVDDDRAVRESLRRSLSFNGYSVELANDGVEALEMVARDRPDAL
MMAR_4529|M.marinum_M               MSVRILVVDDDRAVRESLRRSLSFNGYTVELAHDGVEALEMIASDRPDAL
MUL_4701|M.ulcerans_Agy99           MSVRILVVDDDRAVRESLRRSLSFNGYTVELAHDGVEALEMIASDRPDAL
Mflv_1887|M.gilvum_PYR-GCK          MPVRILVVDDDRAVRESLRRSLSFNGYSVELAQDGREALDLIASDRPDAV
Mvan_4844|M.vanbaalenii_PYR-1       MPVRILVVDDDRAVRESLRRSLSFNGYSVELAQDGREALDLIASDRPDAV
MAB_1076|M.abscessus_ATCC_1997      MPVRILVVDDDRAVRESLRRSLSFNGYSVDLAEDGVDALNVIANDRPDAL
                                      :***.********************:*:**.** :**: :: :****:

TH_1732|M.thermoresistible__bu      VLDVMMPRLDGLEVCRQLRSTGDDLPILVLTARDSVSERVAGLDAGADDY
MSMEG_5488|M.smegmatis_MC2_155      ILDVMMPRLDGLEVCRQLRSTGDDLPILVLTARDSVSERVAGLDAGADDY
Mb1007|M.bovis_AF2122/97            VLDVMMPRLDGLEVCRQLRSTGDDLPILVLTARDSVSERVAGLDAGADDY
Rv0981|M.tuberculosis_H37Rv         VLDVMMPRLDGLEVCRQLRGTGDDLPILVLTARDSVSERVAGLDAGADDY
MAV_1094|M.avium_104                VLDVMMPRLDGLEVCRQLRSTGDDLPILVLTARDSVSERVAGLDAGADDY
MLBr_00174|M.leprae_Br4923          VLDVMMPRLDGLEVCRQLRSTGDDLPILVLTARDSVSERVAGLDAGADDY
MMAR_4529|M.marinum_M               VLDVMMPRLDGLEVCRQLRSTGDDLPILVLTARDSVSERVAGLDAGADDY
MUL_4701|M.ulcerans_Agy99           VLDVMMPRLDGLEVCRQLRSTGDDLPILVLTARDSVSERVAGLDAGADDY
Mflv_1887|M.gilvum_PYR-GCK          VLDVMMPRLDGLEVCRQLRSTGDDLPILVLTARDSVSERVAGLDAGADDY
Mvan_4844|M.vanbaalenii_PYR-1       VLDVMMPRLDGLEVCRQLRSTGDDLPILVLTARDSVSERVAGLDAGADDY
MAB_1076|M.abscessus_ATCC_1997      VLDVMMPKLDGLEVCRRLRSTGDDLPILVLTARDSVSERVAGLDAGADDY
                                    :******:********:**.******************************

TH_1732|M.thermoresistible__bu      LPKPFALEELLARLRALLRRTTPDD--AADSQKLTFADLTLDPVTREVTR
MSMEG_5488|M.smegmatis_MC2_155      LPKPFALEELLARMRALLRRTVSDD--SGDSQKMTFSDLTLDPVTREVTR
Mb1007|M.bovis_AF2122/97            LPKPFALEELLARMRALLRRTKPED--AAESMAMRFSDLTLDPVTREVNR
Rv0981|M.tuberculosis_H37Rv         LPKPFALEELLARMRALLRRTKPED--AAESMAMRFSDLTLDPVTREVNR
MAV_1094|M.avium_104                LPKPFALEELLARMRALLRRTKPED--DAESVAMTFSDLTLDPVTREVTR
MLBr_00174|M.leprae_Br4923          LPKPFALEELLARIRALLRRTKPDD--AAESVAMSFSDLTLDPVTREVAR
MMAR_4529|M.marinum_M               LPKPFALEELLARMRALLRRTKPEDDEAADSVAMTFSDLSLDPVTREVTR
MUL_4701|M.ulcerans_Agy99           LPKPFALEELLARMRALLRRTKLEDDEAADSVAMTFSDLSLDPVTREVTR
Mflv_1887|M.gilvum_PYR-GCK          LPKPFALEELLARMRALLRRTSPVDG-DGESAAMTFSDLTLDPVTREVTR
Mvan_4844|M.vanbaalenii_PYR-1       LPKPFALEELLARMRALLRRTTPDDG-AGESAAMTFSDLSLDPVTREVTR
MAB_1076|M.abscessus_ATCC_1997      LPKPFALEELLARMRALLRRTTIDE--SADAATLSFGDLTLDPVTREVHR
                                    *************:*******   :   .::  : *.**:******** *

TH_1732|M.thermoresistible__bu      GNRQISLTRTEFALLELLIANPRRVLSRSRILEEVWGFDFPTSGNALEVY
MSMEG_5488|M.smegmatis_MC2_155      GGRQISLTRTEFSLLEMLIANPRRVLTRSRILEEVWGFDFPTSGNALEVY
Mb1007|M.bovis_AF2122/97            GQRRISLTRTEFALLEMLIANPRRVLTRSRILEEVWGFDFPTSGNALEVY
Rv0981|M.tuberculosis_H37Rv         GQRRISLTRTEFALLEMLIANPRRVLTRSRILEEVWGFDFPTSGNALEVY
MAV_1094|M.avium_104                GQRRISLTRTEFALLEMLIANPRRVLTRSRILEEVWGFDFPTSGNALEVY
MLBr_00174|M.leprae_Br4923          GQRWISLTRTEFALLEMLIANPRRVLTRSRILEEVWGFDFPTSGNALEVY
MMAR_4529|M.marinum_M               GARRISLTRTEFALLEMLIANPRRVLTRSRILEEVWGFDFPTSGNALEVY
MUL_4701|M.ulcerans_Agy99           GARRISLTRTEFALLEMLIANPRRVLTRSRILEEVWGFDFPTSGNALEVY
Mflv_1887|M.gilvum_PYR-GCK          GNRSISLTRTEFSLLEMLITNPRRVLTRSRILEEVWGFDFPTSGNALEVY
Mvan_4844|M.vanbaalenii_PYR-1       GDRPISLTRTEFSLLEMLIANPRRVLTRSRILEEVWGFDFPTSGNALEVY
MAB_1076|M.abscessus_ATCC_1997      GTRSISLTRTEFALLEMLMANPRRVLTRSRILEEVWGFDFPTSGNALEVY
                                    * * ********:***:*::******:***********************

TH_1732|M.thermoresistible__bu      IGYLRRKTEAEGEPRLIHTVRGVGYVLRETPP
MSMEG_5488|M.smegmatis_MC2_155      IGYLRRKTEAEGEPRLIHTVRGVGYVLRETPP
Mb1007|M.bovis_AF2122/97            VGYLRRKTEADGEPRLIHTVRGVGYVLRETPP
Rv0981|M.tuberculosis_H37Rv         VGYLRRKTEADGEPRLIHTVRGVGYVLRETPP
MAV_1094|M.avium_104                VGYLRRKTEADGEPRLIHTVRGVGYVLRETPP
MLBr_00174|M.leprae_Br4923          VGYLRRKTEADGESRLIHTVRGVGYVLRETPP
MMAR_4529|M.marinum_M               VGYLRRKTEAEGEPRLIHTVRGVGYVLRETPP
MUL_4701|M.ulcerans_Agy99           VGYLRRKTEAEGEPRLIHTVRGVGYVLRETPP
Mflv_1887|M.gilvum_PYR-GCK          VGYLRRKTEAEGEPRLIHTVRGVGYVLRETPP
Mvan_4844|M.vanbaalenii_PYR-1       VGYLRRKTEAEGEPRLIHTVRGVGYVLRETPP
MAB_1076|M.abscessus_ATCC_1997      VGYLRRKTEAEGELRLIHTVRGVGYVLRETPP
                                    :*********:** ******************

species	id	gene	e-value	identity (len)	annotation
M. thermoresistible (build 8)	TH_1732	phoP	-	100% (231)	DNA-binding response regulator PhoP
M. thermoresistible (build 8)	TH_4543	-	1e-57	51.36% (220)	PUTATIVE two component transcriptional regulator, winged helix
M. thermoresistible (build 8)	TH_4055	-	9e-49	44.25% (226)	PUTATIVE two component transcriptional regulator, winged helix