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M. thermoresistible (build 8) TH_4038 (-)

annotation: putative acyl-CoA dehydrogenase domain protein
coordinates: 2991777 - 2992946
length: 390

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_4038--100% (390)putative acyl-CoA dehydrogenase domain protein
M. thermoresistible (build 8)TH_2456-1e-9151.75% (342) PUTATIVE putative acyl-CoA dehydrogenase domain protein
M. thermoresistible (build 8)TH_0804-3e-7742.15% (382) acyl-CoA dehydrogenase

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb1968cfadE183e-6640.11% (369) acyl-CoA dehydrogenase FADE18
M. gilvum PYR-GCKMflv_2335-3e-7845.33% (353) acyl-CoA dehydrogenase domain-containing protein
M. tuberculosis H37RvRv1933cfadE183e-6640.11% (369) acyl-CoA dehydrogenase FADE18
M. leprae Br4923MLBr_00737fadE258e-3527.67% (365) putative acyl-CoA dehydrogenase
M. abscessus ATCC 19977MAB_3123-1e-7342.90% (366) putative acyl-CoA dehydrogenase
M. marinum MMMAR_2861fadE184e-7039.84% (369) acyl-CoA dehydrogenase FadE18
M. avium 104MAV_1838-4e-7141.35% (370) acyl-CoA dehydrogenase protein
M. smegmatis MC2 155MSMEG_6585-1e-8143.98% (382) acyl-CoA dehydrogenase
M. ulcerans Agy99MUL_2893fadE182e-6939.57% (369) acyl-CoA dehydrogenase FadE18
M. vanbaalenii PYR-1Mvan_4312-8e-7643.47% (352) acyl-CoA dehydrogenase domain-containing protein

CLUSTAL 2.0.9 multiple sequence alignment


Mb1968c|M.bovis_AF2122/97           -----------------MDFRYSTEQ--------------------DDFR
Rv1933c|M.tuberculosis_H37Rv        -----------------MDFRYSTEQ--------------------DDFR
MMAR_2861|M.marinum_M               -----------------MDFRYSTEQ--------------------DDFR
MUL_2893|M.ulcerans_Agy99           -----------------MDFRYSTEQ--------------------DDFR
Mflv_2335|M.gilvum_PYR-GCK          -----------------MT-ISVAER--------------------AELR
Mvan_4312|M.vanbaalenii_PYR-1       -----------------MT-ISVAER--------------------AELR
TH_4038|M.thermoresistible__bu      -----------------VS-TPPAERTKEVDEMTDIPDAFAATDAQDELR
MAV_1838|M.avium_104                -----------------MTGLSLDES--------------------RELA
MSMEG_6585|M.smegmatis_MC2_155      MAEELVDQPDKVAEELVDQPDKVAEELVDQPDKVAETTEFRFTDEQGQLR
MAB_3123|M.abscessus_ATCC_1997      MSASEDHQTRMSASEDNQTRMSASEDNQAQIN------EFEFTEEHGDLR
MLBr_00737|M.leprae_Br4923          --------MVGWSGNPLFDLFKLPEEH-------------------NELR
                                                            *                      :: 

Mb1968c|M.bovis_AF2122/97           ASLRGFLGRGAP---VREMAAA-----DGSDRRLWQRLCTELELPALHVP
Rv1933c|M.tuberculosis_H37Rv        ASLRGFLGRGAP---VREMAAA-----DGSDRRLWQRLCTELELPALHVP
MMAR_2861|M.marinum_M               ESLRGFLRDQAPPARVRQVAAV-----GGHDKKLWHRLCAELELPALHAP
MUL_2893|M.ulcerans_Agy99           ESLRGFLRDQAPPARVRQVAAV-----GGHDKKLWHRLCAELELPALHAP
Mflv_2335|M.gilvum_PYR-GCK          TAVGKLLADKCTEDDVRRVRES----DEGFDRDLWRRLADQ-GVLGMLVD
Mvan_4312|M.vanbaalenii_PYR-1       TAVGELLAERCTESDVRRVMTS----DEGFDRDLWRQLANQ-GVLGMLVD
TH_4038|M.thermoresistible__bu      RTVRGFFEKKMPEHEVRRIMET----PEGYDRAVWRQMADQLGLQGVAIP
MAV_1838|M.avium_104                RSVRAACERFAPEERVRAIAYNGGGVDAGFDTELWKVLCAQVGVAAIGMP
MSMEG_6585|M.smegmatis_MC2_155      AAVRKFGAEYFDEQTVRRLMES----EPRFDPAVWARLGAELGVLGLAVP
MAB_3123|M.abscessus_ATCC_1997      SLVRSWCERVWTPKHVRQIAEA-----GSVDLDAWRALGSELGVVGLSLP
MLBr_00737|M.leprae_Br4923          ATIRALAEKEIAPHAADVDQRA------RFPEEALAALNAS-GFNAIHVP
                                      :            .                     :  .  . .:   

Mb1968c|M.bovis_AF2122/97           PEHGGLGATLVETAIAFAELGRALTPIPFAAT-VFAIEAILRMG-DDEQR
Rv1933c|M.tuberculosis_H37Rv        PEHGGLGATLVETAIAFAELGRALTPIPFAAT-VFAIEAILRMG-DDEQR
MMAR_2861|M.marinum_M               PEYGGAGGTLVETAIAFGELGRALTPVPFAAT-ILAIEAILRMG-DSEQR
MUL_2893|M.ulcerans_Agy99           PEYGGAGGTLVETAIAFGELGRALTPVPFAAT-ILAIEAILRMG-DSEQR
Mflv_2335|M.gilvum_PYR-GCK          SEYGGLGFGAQELEAVAEETGAALLPAPFISSAVLTVALINAVG-SDEDK
Mvan_4312|M.vanbaalenii_PYR-1       GEYGGLGFGALELEAVAEETGTAALPAPFISSAVLTVALINAAG-SDEDK
TH_4038|M.thermoresistible__bu      EEFGGSGFGYSELGVVVEETGRALLPGPFFGSVVLAGTALLCSA-DDAAK
MAV_1838|M.avium_104                EDLGGAGFDATALGVVAHELGRALAPVPFVASAVLATGLLLATRESDPDS
MSMEG_6585|M.smegmatis_MC2_155      EADGGAGGTLVDQAVAVEELGAALACGPLIGTVYLSIPALVAAS-AGPVR
MAB_3123|M.abscessus_ATCC_1997      EQHGGGGLGVIELSIVAEELGRALACLPWISSAALGATALVSSG-DDSAL
MLBr_00737|M.leprae_Br4923          EEYGGQGADSVAACIVIEEVARVDASASLIPAVNKLGTMGLILRGSEELK
                                       ** *        .  * . .    .   :                  

Mb1968c|M.bovis_AF2122/97           KRLLAGLLTGARIGTIAVSGHDVASATTVRAVRRDGRP---ALTGECTPV
Rv1933c|M.tuberculosis_H37Rv        KRLLAGLLTGARIGTIAVSGHDVASATTVRAVRRDGRP---ALTGECTPV
MMAR_2861|M.marinum_M               KGLLSGLLSGDRIGALAAAGPDLS-VTSVRAGRRDGRP---VLTGECAPV
MUL_2893|M.ulcerans_Agy99           KGLLSGLLSGDRIGALAAAGPDLS-VTSVRAGRRDGRP---VLTGECAPV
Mflv_2335|M.gilvum_PYR-GCK          QRLLPGLADGTAIGTVALTGPAGSWSEDGVDVRAGADG---ALDGVAHFV
Mvan_4312|M.vanbaalenii_PYR-1       QRLLPALADGTAIGTVALTGKSGSWTPEGVDVQAAADG---TLTGSAHYV
TH_4038|M.thermoresistible__bu      SRYLPGIATGETIAALALTEQSGRWSADAVQTTARHDGGRWIINGSKTFV
MAV_1838|M.avium_104                EQRLSGLMEGHRTAAAAVTGDGGLWQRDSVTLVANANIDGWAVNGTVRHV
MSMEG_6585|M.smegmatis_MC2_155      DELLGALVEGARTAAFAVPDRAGAFDPALVGVTASADA---TLTGTVERI
MAB_3123|M.abscessus_ATCC_1997      AEWVPALAAGEKTITLAG-GRTRLADAITVSAESDTDG--WKLTGDTEHV
MLBr_00737|M.leprae_Br4923          KQVLPSLAAEGAMASYALSEREAGSDAASMRTRAKADGDDWILNGFKCWI
                                       : .:       : *                         : *    :

Mb1968c|M.bovis_AF2122/97           LHGHVADLFVVPAVAD-----GSIVLHVVAADAPGVTVTP----LPSFDI
Rv1933c|M.tuberculosis_H37Rv        LHGHVADLFVVPAVAD-----GSIVLHVVAADAPGVTVTP----LPSFDI
MMAR_2861|M.marinum_M               LHGHVADLFVVPAESD-----GAVILYVVDAAAPGVAVVG----LPSFDI
MUL_2893|M.ulcerans_Agy99           LHGHVADLFVVPAESD-----GAVILYVVDAAAPGVAVVG----LPSFDI
Mflv_2335|M.gilvum_PYR-GCK          TWGQVADVVLVVARTD-----DGVGVFEIATDATGFERTA----ATVFDP
Mvan_4312|M.vanbaalenii_PYR-1       TWGQVADVVLVVARTD-----DGFGVFEVSVGADGFERSA----ATVFDP
TH_4038|M.thermoresistible__bu      LDGHAADLLLVAARTD-----SGISLLAVDQ-TEGLTRRM----LSTLDP
MAV_1838|M.avium_104                LNGCAANDLVVVAKAD-----DQPALFLIDPMAEGVAVEA----ERVLDG
MSMEG_6585|M.smegmatis_MC2_155      VDGAAADVFLVAATAP-----DGVALYAVDA--SDVQRTP----LTTLDL
MAB_3123|M.abscessus_ATCC_1997      PDGATADVILVLADTD-----SGPSLFAVDGDAPGVDRHS----LATLDM
MLBr_00737|M.leprae_Br4923          TNGGKSTWYTVMAVTDPDKGANGISAFIVHKDDEGFSIGPKEKKLGIKGS
                                      *  :    * * :      .      :     ..            . 

Mb1968c|M.bovis_AF2122/97           TRPVATLRLAGSP-AEPLTAGT--PDDMERVLDVARVLLAAEMLGGAEAC
Rv1933c|M.tuberculosis_H37Rv        TRPVATLRLAGSP-AEPLTAGT--PDDMERVLDVARVLLAAEMLGGAEAC
MMAR_2861|M.marinum_M               TRPVAKLRLVRAP-AEALAASS--ADEVARLLDVARVLLAAEMLGGAEAC
MUL_2893|M.ulcerans_Agy99           TRPVAKLRLVRAP-AEALAASS--ADEVARLLDVARVLLAAEMLGGAEAC
Mflv_2335|M.gilvum_PYR-GCK          TVRLSTYTFAGTP-ARRLGTAG--WEAVREAMDYAVVASAGEQVGGAKRI
Mvan_4312|M.vanbaalenii_PYR-1       TVRLSTFSFAGTP-ARRLGTAG--WDAAKEALDHAVIASAGEQVGGARRI
TH_4038|M.thermoresistible__bu      TRRQGRIDFTDTP-AELIGAEGQAWPSLSHALDIAAALLALEQVGGAQRC
MAV_1838|M.avium_104                TRPMATITFTGAT-ALKLTGREAVDTIIEHNIDVALAVLSAEQVGACERV
MSMEG_6585|M.smegmatis_MC2_155      TRPQATIALTDTP-GRLVSGPGEAERVIGHALQVGAALLAVEQVGAAQHL
MAB_3123|M.abscessus_ATCC_1997      TRRQANIHFNSAP-ARLIGAQGRGAEAVATALDVAATVLAAEQAGIAAHM
MLBr_00737|M.leprae_Br4923          PTTELYFDKCRIPGDRIIGEPGTGFKTALATLDHTRPTIGAQAVGIAQGA
                                    .           .    :             ::      . :  * .   

Mb1968c|M.bovis_AF2122/97           LDLAVQYAGRRTQFDRPIGSFQAVKHACADMMIEIDATRATVMFAAMSAA
Rv1933c|M.tuberculosis_H37Rv        LDLAVQYAGRRTQFDRPIGSFQAVKHACADMMIEIDATRATVMFAAMSAA
MMAR_2861|M.marinum_M               LDLAIEYACSRKQFDRPIGSFQAVKHRCADMMIEIDATRAAVMFAQLCAA
MUL_2893|M.ulcerans_Agy99           LDLAIEYACSRKQFDRPIGSFQAVKHRCADMMIEIDATRAAVMFAQLCAA
Mflv_2335|M.gilvum_PYR-GCK          FDITIAYLKTRFQFGRAIGSFQALKHMAADLLLEVESATSAAQHAAAVFD
Mvan_4312|M.vanbaalenii_PYR-1       FDMTVDYLKTRIQFGRQIGSFQALKHMAADLLIEVENATSAAQHAASEKA
TH_4038|M.thermoresistible__bu      LEIAVDYAKTRHQFGKPIGSFQAIRHRFADLMLEIECARGAAQYAVYAAA
MAV_1838|M.avium_104                LEIACEYARTREQFGRPIGSFQAIKHKCADMLVDLEWARSASQAALEAVV
MSMEG_6585|M.smegmatis_MC2_155      LDLSVDYAKSRLQFGRPIGSFQAVKHRLADDLVDLEHARSAAYHAVWALA
MAB_3123|M.abscessus_ATCC_1997      LDVTTEYAKSRIQFGRIIGSFQAVKHRLADMAAATGNVRGAAYHAAWSHD
MLBr_00737|M.leprae_Br4923          LDAAIVYTKDRKQFGESISTFQSIQFMLADMAMKVEAARLIVYAAAARAE
                                    :: :  *   * **.. *.:**:::.  **       .      *     

Mb1968c|M.bovis_AF2122/97           --NGDELQTVAPLAKAQTAETFVLCAGSALQIHGAIAFTWEHDLHLYYRR
Rv1933c|M.tuberculosis_H37Rv        --NGDELQTVAPLAKAQTAETFVLCAGSALQIHGAIAFTWEHDLHLYYRR
MMAR_2861|M.marinum_M               --GGDELHATAPLAKAQAADTYVLCAGSAIQVHGGIAFTWEHDLHLYFRR
MUL_2893|M.ulcerans_Agy99           --GGDELHATAPLAKAQAAGTYVLCAGSAIQVHGGIAFTWEHDLHLYFRR
Mflv_2335|M.gilvum_PYR-GCK          --DPEARDGAVALAGFACAEAYVKTAMAAVQMHGGIGFTWEHPCHLYVRR
Mvan_4312|M.vanbaalenii_PYR-1       G-NSENADGAVALAGFACAEAYETIAMNAIQMHGGIGFTWEHPAHIFLRR
TH_4038|M.thermoresistible__bu      R-GLDELPAAASLAKAYCTDVYTKAAGANIQIHGGIGFTWEHPAHMYFKR
MAV_1838|M.avium_104                ---SGERDWRASMAKAVCSESLRNAAHANVQIHGGIGFTWEDSAHLYLRR
MSMEG_6585|M.smegmatis_MC2_155      D-GSDDPALAASIAQATASAALTKIATDTIQVHGGIGFTWEHQAHLYFKR
MAB_3123|M.abscessus_ATCC_1997      HPSLDDPALATSIAQQVASAGAVEVTAKAIQSHGGIGFTWEHPAHLYYKR
MLBr_00737|M.leprae_Br4923          R-GEPDLGFISAASKCFASDIAMEVTTDAVQLFGGAGYTSDFPVERFMRD
                                               . :    :      :   :* .*. .:* :   . : : 

Mb1968c|M.bovis_AF2122/97           AKTTEALFGSSARNRALLAERAGLVKA-----------------
Rv1933c|M.tuberculosis_H37Rv        AKTTEALFGSSARNRALLAERAGLVKA-----------------
MMAR_2861|M.marinum_M               AKTTEALFGSSAHHRSLLADRVGL--------------------
MUL_2893|M.ulcerans_Agy99           AKTTEALFGSSAHHRSLLADRVGL--------------------
Mflv_2335|M.gilvum_PYR-GCK          ARSGLQLFGDSGLHRERYLISKGA--------------------
Mvan_4312|M.vanbaalenii_PYR-1       ARTGLHLFGGPRLHRERYLVSKGA--------------------
TH_4038|M.thermoresistible__bu      AKSSEHLLGDAAYHRGLLADRAGI--------------------
MAV_1838|M.avium_104                ARTDEVLLGGPGQHWDRVGLRVL---------------------
MSMEG_6585|M.smegmatis_MC2_155      ATTDAALLGTAEAHRDRIAELILDRAVSDQATIDRAPRVATGTN
MAB_3123|M.abscessus_ATCC_1997      AVSNSALFGGRAVHAERIAKEVIDA-------------------
MLBr_00737|M.leprae_Br4923          AKITQIYEGTNQIQRVVMSRALLR--------------------
                                    *       *    :