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TGLSLDESRELARSVRAACERFAPEERVRAIAYNGGGVDAGFDTELWKVLCAQVGVAAIGMPEDLGGAGF DATALGVVAHELGRALAPVPFVASAVLATGLLLATRESDPDSEQRLSGLMEGHRTAAAAVTGDGGLWQRD SVTLVANANIDGWAVNGTVRHVLNGCAANDLVVVAKADDQPALFLIDPMAEGVAVEAERVLDGTRPMATI TFTGATALKLTGREAVDTIIEHNIDVALAVLSAEQVGACERVLEIACEYARTREQFGRPIGSFQAIKHKC ADMLVDLEWARSASQAALEAVVSGERDWRASMAKAVCSESLRNAAHANVQIHGGIGFTWEDSAHLYLRRA RTDEVLLGGPGQHWDRVGLRVL*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_1838 | - | - | 100% (373) | acyl-CoA dehydrogenase protein |
| M. avium 104 | MAV_2570 | - | e-148 | 71.05% (380) | putative acyl-CoA dehydrogenase |
| M. avium 104 | MAV_1267 | - | 3e-45 | 35.03% (334) | acyl-CoA dehydrogenase domain-containing protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1968c | fadE18 | 4e-50 | 36.67% (360) | acyl-CoA dehydrogenase FADE18 |
| M. gilvum PYR-GCK | Mflv_0345 | - | 2e-65 | 40.11% (369) | acyl-CoA dehydrogenase domain-containing protein |
| M. tuberculosis H37Rv | Rv1933c | fadE18 | 4e-50 | 36.67% (360) | acyl-CoA dehydrogenase FADE18 |
| M. leprae Br4923 | MLBr_00737 | fadE25 | 4e-19 | 25.81% (372) | putative acyl-CoA dehydrogenase |
| M. abscessus ATCC 19977 | MAB_3123 | - | 9e-56 | 36.90% (374) | putative acyl-CoA dehydrogenase |
| M. marinum M | MMAR_2861 | fadE18 | 1e-56 | 39.52% (372) | acyl-CoA dehydrogenase FadE18 |
| M. smegmatis MC2 155 | MSMEG_1905 | - | 1e-64 | 40.00% (370) | acyl-CoA dehydrogenase protein |
| M. thermoresistible (build 8) | TH_3035 | - | 1e-140 | 65.42% (373) | PUTATIVE acyl-CoA dehydrogenase protein |
| M. ulcerans Agy99 | MUL_2893 | fadE18 | 3e-56 | 39.52% (372) | acyl-CoA dehydrogenase FadE18 |
| M. vanbaalenii PYR-1 | Mvan_0393 | - | 5e-62 | 39.57% (369) | acyl-CoA dehydrogenase domain-containing protein |
CLUSTAL 2.0.9 multiple sequence alignment
MAV_1838|M.avium_104 -------------------------------MTGLSLDESRELARSVRAA
TH_3035|M.thermoresistible__bu -------------------------------MTTLSIDERQQLAKSVRAA
MSMEG_1905|M.smegmatis_MC2_155 -------------------------------MT-ISVAERAELAAAVREL
Mflv_0345|M.gilvum_PYR-GCK --------------------MADTAG------EWVFSDEQNQLRAAVRAF
Mvan_0393|M.vanbaalenii_PYR-1 --------------------MADSQGA-----EYVFTEEQGQLRAAVRRF
MAB_3123|M.abscessus_ATCC_1997 MSASEDHQTRMSASEDNQTRMSASEDNQAQINEFEFTEEHGDLRSLVRSW
Mb1968c|M.bovis_AF2122/97 -------------------------------MDFRYSTEQDDFRASLRGF
Rv1933c|M.tuberculosis_H37Rv -------------------------------MDFRYSTEQDDFRASLRGF
MMAR_2861|M.marinum_M -------------------------------MDFRYSTEQDDFRESLRGF
MUL_2893|M.ulcerans_Agy99 -------------------------------MDFRYSTEQDDFRESLRGF
MLBr_00737|M.leprae_Br4923 ---------------------MVGWSGNPLFDLFKLPEEHNELRATIRAL
* :: :*
MAV_1838|M.avium_104 CERFAPEERVRAIAYNGGGVDAGFDTELWKVLCAQVGVAAIGMPEDLGGA
TH_3035|M.thermoresistible__bu CERLSSEERVRAVAYNGIHQHKGFDAELWTVLCSQVGVTAIALPENLGGA
MSMEG_1905|M.smegmatis_MC2_155 LQNECTEQDVRQTISS----DEGYDPQLWRKLAAQ-GVTGLLIDPEYGGV
Mflv_0345|M.gilvum_PYR-GCK CADHVDESSVRAAMESDP----PFDAKVWSRLGSELGVLGMAVPESAGGA
Mvan_0393|M.vanbaalenii_PYR-1 CADHIDETAVRAQMASEP----RFDPKVWARLGSELGVLGMSVPESHGGA
MAB_3123|M.abscessus_ATCC_1997 CERVWTPKHVRQIAEAG-----SVDLDAWRALGSELGVVGLSLPEQHGGG
Mb1968c|M.bovis_AF2122/97 LGRGAP---VREMAAAD-----GSDRRLWQRLCTELELPALHVPPEHGGL
Rv1933c|M.tuberculosis_H37Rv LGRGAP---VREMAAAD-----GSDRRLWQRLCTELELPALHVPPEHGGL
MMAR_2861|M.marinum_M LRDQAPPARVRQVAAVG-----GHDKKLWHRLCAELELPALHAPPEYGGA
MUL_2893|M.ulcerans_Agy99 LRDQAPPARVRQVAAVG-----GHDKKLWHRLCAELELPALHAPPEYGGA
MLBr_00737|M.leprae_Br4923 AEKEIAPHAADVDQRAR------FPEEALAALNAS-GFNAIHVPEEYGGQ
. * :. . .: . **
MAV_1838|M.avium_104 GFDATALGVVAHELGRALAPVPFVASAVLATGLLLATRESDPDSEQRLSG
TH_3035|M.thermoresistible__bu GYGASALGAVAHELGRSLAAVPFVASAVLATTLLVAAQTEQPEVDRRLAG
MSMEG_1905|M.smegmatis_MC2_155 GLGALELEAVAEETGAALLPAPFIGSAVLATALIEAAGTAE-DKQRLLPG
Mflv_0345|M.gilvum_PYR-GCK GGNLVDQAVAVEQLGAALACGPLFGTVYLAIPALVAA----SGGQELLGP
Mvan_0393|M.vanbaalenii_PYR-1 GGTLVDQAVAVEQLGAALACGPLFGTVYLAIPALVAS----SQPGDLLAP
MAB_3123|M.abscessus_ATCC_1997 GLGVIELSIVAEELGRALACLPWISSAALGATALVS-----SGDDSALAE
Mb1968c|M.bovis_AF2122/97 GATLVETAIAFAELGRALTPIPFAATVFAIEAILRMG--DDEQRKRLLAG
Rv1933c|M.tuberculosis_H37Rv GATLVETAIAFAELGRALTPIPFAATVFAIEAILRMG--DDEQRKRLLAG
MMAR_2861|M.marinum_M GGTLVETAIAFGELGRALTPVPFAATILAIEAILRMG--DSEQRKGLLSG
MUL_2893|M.ulcerans_Agy99 GGTLVETAIAFGELGRALTPVPFAATILAIEAILRMG--DSEQRKGLLSG
MLBr_00737|M.leprae_Br4923 GADSVAACIVIEEVARVDASASLIPAVNKLGTMGLILRGSEELKKQVLPS
* . : . . : *
MAV_1838|M.avium_104 LMEGHRTAAAAVTGDGG-LWQRDSVTLVANANIDGWAVNGTVRHVLNGCA
TH_3035|M.thermoresistible__bu LVEGSRTAAAVITSDGG-LWRPDAIPVTAEQSTAGWVLTGTARHILHGSA
MSMEG_1905|M.smegmatis_MC2_155 LAEGTSIATVAVTGARG-TWAKEGVAVKATERADGHTLNGNAHYVLSGQI
Mflv_0345|M.gilvum_PYR-GCK LVDGTRTAAFAVRDDAG-AFDASSVEVQAVPTEQGWALSGTVERVVDAGA
Mvan_0393|M.vanbaalenii_PYR-1 LIEGIRTAAFAVPDAGG-DFDADAVTVEAIPTDQGWTLTGTVQRVVDAGA
MAB_3123|M.abscessus_ATCC_1997 WVPALAAGEKTITLAGGRTRLADAITVSAESDTDGWKLTGDTEHVPDGAT
Mb1968c|M.bovis_AF2122/97 LLTGARIGTIAVS---G-HDVASATTVRAVRRDGRPALTGECTPVLHGHV
Rv1933c|M.tuberculosis_H37Rv LLTGARIGTIAVS---G-HDVASATTVRAVRRDGRPALTGECTPVLHGHV
MMAR_2861|M.marinum_M LLSGDRIGALAAA---G-PDLS-VTSVRAGRRDGRPVLTGECAPVLHGHV
MUL_2893|M.ulcerans_Agy99 LLSGDRIGALAAA---G-PDLS-VTSVRAGRRDGRPVLTGECAPVLHGHV
MLBr_00737|M.leprae_Br4923 LAAEGAMASYALSEREA-GSDAASMRTRAKADGDDWILNGFKCWITNGGK
. . . * :.* : .
MAV_1838|M.avium_104 ANDLVVVAKAD--DQ---PALFLIDPMAEGVAVEA-ERVLDGTRPMATIT
TH_3035|M.thermoresistible__bu ADDLVVVATIG--EV---PALFVLDAMAPEVFRKD-EQVLDHTRPMATIT
MSMEG_1905|M.smegmatis_MC2_155 ADVLLVVARTGGDDVGG-VGIFEVTPDATGLTRAA-ATVFDPSVRLSTFT
Mflv_0345|M.gilvum_PYR-GCK ADVLLVAATTP--DG---VGLFVVEADSLGVQRIR-LTTLDLTRPQATVG
Mvan_0393|M.vanbaalenii_PYR-1 ADVVLVAAAGP--DG---LGLYAIEADNIGVQRIP-LTTLDLTRPQATVG
MAB_3123|M.abscessus_ATCC_1997 ADVILVLADTD--SG---PSLFAVDGDAPGVDRHS-LATLDMTRRQANIH
Mb1968c|M.bovis_AF2122/97 ADLFVVPAVAD--GS---IVLHVVAADAPGVTVTP-LPSFDITRPVATLR
Rv1933c|M.tuberculosis_H37Rv ADLFVVPAVAD--GS---IVLHVVAADAPGVTVTP-LPSFDITRPVATLR
MMAR_2861|M.marinum_M ADLFVVPAESD--GA---VILYVVDAAAPGVAVVG-LPSFDITRPVAKLR
MUL_2893|M.ulcerans_Agy99 ADLFVVPAESD--GA---VILYVVDAAAPGVAVVG-LPSFDITRPVAKLR
MLBr_00737|M.leprae_Br4923 STWYTVMAVTDPDKGANGISAFIVHKDDEGFSIGPKEKKLGIKGSPTTEL
: * * . : . :. . :.
MAV_1838|M.avium_104 FTGAT----ALKLTGREAVDTIIEHNIDVALAVLSAEQVGACERVLEIAC
TH_3035|M.thermoresistible__bu FSSAP----ATLVSRRESIPELVSRTMDLTMAVLSAEQVGACERLLEIST
MSMEG_1905|M.smegmatis_MC2_155 FTDTP----ARRIG--TAGWDAVSHALDLAVIALAGEQVGGTRRIFDITI
Mflv_0345|M.gilvum_PYR-GCK LLDAP----AQLIAGPEEAERVITHALQVGAALLAVEQVGAAQHLLDLSV
Mvan_0393|M.vanbaalenii_PYR-1 LFHAP----ARLVAGPAEAERVITHALQIGAALLAVEQVGAAQHLLDLTV
MAB_3123|M.abscessus_ATCC_1997 FNSAP----ARLIGAQGRGAEAVATALDVAATVLAAEQAGIAAHMLDVTT
Mb1968c|M.bovis_AF2122/97 LAGSP----AEPLT--AGTPDDMERVLDVARVLLAAEMLGGAEACLDLAV
Rv1933c|M.tuberculosis_H37Rv LAGSP----AEPLT--AGTPDDMERVLDVARVLLAAEMLGGAEACLDLAV
MMAR_2861|M.marinum_M LVRAP----AEALA--ASSADEVARLLDVARVLLAAEMLGGAEACLDLAI
MUL_2893|M.ulcerans_Agy99 LVRAP----AEALA--ASSADEVARLLDVARVLLAAEMLGGAEACLDLAI
MLBr_00737|M.leprae_Br4923 YFDKCRIPGDRIIGEPGTGFKTALATLDHTRPTIGAQAVGIAQGALDAAI
: :: :. : * :: :
MAV_1838|M.avium_104 EYARTREQFGRPIGSFQAIKHKCADMLVDLEWARSASQAALEAVVS---G
TH_3035|M.thermoresistible__bu EYARTRHQFNRPIGSFQAVKHKCADTLVDLEWARSASQAALEAMDDGLTG
MSMEG_1905|M.smegmatis_MC2_155 DYLKTRIQFGRAIGSFQALKHMAADLLVQVESSTSAAQHAAAEKAAG-SD
Mflv_0345|M.gilvum_PYR-GCK DYAKNRLQFGRPIGSFQAVKHRLADDLVAVEHARSTAYHAVWALSDGS-D
Mvan_0393|M.vanbaalenii_PYR-1 DYAKNRLQFGRPIGSFQAVKHRLADDLVALEHARSTAYHAVWALTDGS-D
MAB_3123|M.abscessus_ATCC_1997 EYAKSRIQFGRIIGSFQAVKHRLADMAAATGNVRGAAYHAAWSHDHPSLD
Mb1968c|M.bovis_AF2122/97 QYAGRRTQFDRPIGSFQAVKHACADMMIEIDATRATVMFAAMSAANG--D
Rv1933c|M.tuberculosis_H37Rv QYAGRRTQFDRPIGSFQAVKHACADMMIEIDATRATVMFAAMSAANG--D
MMAR_2861|M.marinum_M EYACSRKQFDRPIGSFQAVKHRCADMMIEIDATRAAVMFAQLCAAGG--D
MUL_2893|M.ulcerans_Agy99 EYACSRKQFDRPIGSFQAVKHRCADMMIEIDATRAAVMFAQLCAAGG--D
MLBr_00737|M.leprae_Br4923 VYTKDRKQFGESISTFQSIQFMLADMAMKVEAARLIVYAAAARAERGE-P
* * **.. *.:**:::. ** *
MAV_1838|M.avium_104 ERDWRASMAKAVCSESLRNAAHANVQIHGGIGFTWEDSAHLYLRRARTDE
TH_3035|M.thermoresistible__bu ESTWYASMAKAVCSEALQGAAHVNVQIHGGLGFTWEDSAHLYLRRARTDE
MSMEG_1905|M.smegmatis_MC2_155 DAAGAIALAGFFCAEAYNTTAMQAVQMHGGIGFTWEHPAHLFVRRARTGL
Mflv_0345|M.gilvum_PYR-GCK DPALAVSIAQATTSAAFVRVATDTIQVHGGIGFTWEHQAHLYYKRAYTDA
Mvan_0393|M.vanbaalenii_PYR-1 DPALAVSIAQATCSEALVRVATDTIQVHGGIGFTWEHQAHLYYKRAYTDA
MAB_3123|M.abscessus_ATCC_1997 DPALATSIAQQVASAGAVEVTAKAIQSHGGIGFTWEHPAHLYYKRAVSNS
Mb1968c|M.bovis_AF2122/97 ELQTVAPLAKAQTAETFVLCAGSALQIHGAIAFTWEHDLHLYYRRAKTTE
Rv1933c|M.tuberculosis_H37Rv ELQTVAPLAKAQTAETFVLCAGSALQIHGAIAFTWEHDLHLYYRRAKTTE
MMAR_2861|M.marinum_M ELHATAPLAKAQAADTYVLCAGSAIQVHGGIAFTWEHDLHLYFRRAKTTE
MUL_2893|M.ulcerans_Agy99 ELHATAPLAKAQAAGTYVLCAGSAIQVHGGIAFTWEHDLHLYFRRAKTTE
MLBr_00737|M.leprae_Br4923 DLGFISAASKCFASDIAMEVTTDAVQLFGGAGYTSDFPVERFMRDAKITQ
: . : : : :* .*. .:* : . : : *
MAV_1838|M.avium_104 VLLGGPGQHWDRVGLR--VL---------------
TH_3035|M.thermoresistible__bu VLFGKPSEHWDRLALESGIFTGGNAKR--------
MSMEG_1905|M.smegmatis_MC2_155 QLFGSSAQHRERYLTAKGA----------------
Mflv_0345|M.gilvum_PYR-GCK ALLGGAEEHRARVADFVLVVAPEKDAPRVATGMPS
Mvan_0393|M.vanbaalenii_PYR-1 ALLGSAEAHRARVAELVLDVAPRKDAPRVATGMPS
MAB_3123|M.abscessus_ATCC_1997 ALFGGRAVHAERIAKEVIDA---------------
Mb1968c|M.bovis_AF2122/97 ALFGSSARNRALLAERAGLVKA-------------
Rv1933c|M.tuberculosis_H37Rv ALFGSSARNRALLAERAGLVKA-------------
MMAR_2861|M.marinum_M ALFGSSAHHRSLLADRVGL----------------
MUL_2893|M.ulcerans_Agy99 ALFGSSAHHRSLLADRVGL----------------
MLBr_00737|M.leprae_Br4923 IYEGTNQIQRVVMSRALLR----------------
* :