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MSASEDHQTRMSASEDNQTRMSASEDNQAQINEFEFTEEHGDLRSLVRSWCERVWTPKHVRQIAEAGSVD LDAWRALGSELGVVGLSLPEQHGGGGLGVIELSIVAEELGRALACLPWISSAALGATALVSSGDDSALAE WVPALAAGEKTITLAGGRTRLADAITVSAESDTDGWKLTGDTEHVPDGATADVILVLADTDSGPSLFAVD GDAPGVDRHSLATLDMTRRQANIHFNSAPARLIGAQGRGAEAVATALDVAATVLAAEQAGIAAHMLDVTT EYAKSRIQFGRIIGSFQAVKHRLADMAAATGNVRGAAYHAAWSHDHPSLDDPALATSIAQQVASAGAVEV TAKAIQSHGGIGFTWEHPAHLYYKRAVSNSALFGGRAVHAERIAKEVIDA
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. abscessus ATCC 19977 | MAB_3123 | - | - | 100% (400) | putative acyl-CoA dehydrogenase |
M. abscessus ATCC 19977 | MAB_4159 | - | 1e-42 | 33.24% (373) | acyl-CoA dehydrogenase |
M. abscessus ATCC 19977 | MAB_0593c | - | 9e-39 | 36.99% (346) | acyl-CoA dehydrogenase FadE |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb1968c | fadE18 | 3e-47 | 35.71% (364) | acyl-CoA dehydrogenase FADE18 |
M. gilvum PYR-GCK | Mflv_0345 | - | 6e-79 | 44.86% (370) | acyl-CoA dehydrogenase domain-containing protein |
M. tuberculosis H37Rv | Rv1933c | fadE18 | 3e-47 | 35.71% (364) | acyl-CoA dehydrogenase FADE18 |
M. leprae Br4923 | MLBr_00737 | fadE25 | 7e-28 | 27.95% (365) | putative acyl-CoA dehydrogenase |
M. marinum M | MMAR_1954 | fadE18_1 | 3e-54 | 40.74% (324) | acyl-CoA dehydrogenase FadE18_1 |
M. avium 104 | MAV_2570 | - | 6e-56 | 36.17% (376) | putative acyl-CoA dehydrogenase |
M. smegmatis MC2 155 | MSMEG_6585 | - | 2e-81 | 45.48% (376) | acyl-CoA dehydrogenase |
M. thermoresistible (build 8) | TH_0804 | - | 4e-83 | 44.30% (395) | acyl-CoA dehydrogenase |
M. ulcerans Agy99 | MUL_2176 | fadE18_1 | 8e-55 | 41.05% (324) | acyl-CoA dehydrogenase FadE18_1 |
M. vanbaalenii PYR-1 | Mvan_0393 | - | 5e-84 | 46.61% (369) | acyl-CoA dehydrogenase domain-containing protein |
CLUSTAL 2.0.9 multiple sequence alignment Mb1968c|M.bovis_AF2122/97 --------------------------------------MDFRYSTEQDDF Rv1933c|M.tuberculosis_H37Rv --------------------------------------MDFRYSTEQDDF Mflv_0345|M.gilvum_PYR-GCK --------------------------------MADTAG-EWVFSDEQNQL Mvan_0393|M.vanbaalenii_PYR-1 --------------------------------MADSQGAEYVFTEEQGQL MSMEG_6585|M.smegmatis_MC2_155 MAEELVDQPDKVAEELVDQPDKVAEELVDQPDKVAETT-EFRFTDEQGQL TH_0804|M.thermoresistible__bu -----------VAEELAEQPDNAAEELAEQPDNAAGLSPTFTFTEEQQQL MMAR_1954|M.marinum_M -----------------------------------MSTGDLLYSDTEEAL MUL_2176|M.ulcerans_Agy99 -----------------------------------MSTGDLLYSDTEEAL MAV_2570|M.avium_104 -----------------------------MTALSADERQELAQSVRSACE MAB_3123|M.abscessus_ATCC_1997 -------MSASEDHQTRMSASEDNQTRMSASEDNQAQINEFEFTEEHGDL MLBr_00737|M.leprae_Br4923 ----------------------------MVGWSGNPLFDLFKLPEEHNEL . Mb1968c|M.bovis_AF2122/97 RASLRGFLGRGAPVREMAAADGS----DRRLWQRLCTELELPALHVPPEH Rv1933c|M.tuberculosis_H37Rv RASLRGFLGRGAPVREMAAADGS----DRRLWQRLCTELELPALHVPPEH Mflv_0345|M.gilvum_PYR-GCK RAAVRAFCADHVDESSVRAAMESDPPFDAKVWSRLGSELGVLGMAVPESA Mvan_0393|M.vanbaalenii_PYR-1 RAAVRRFCADHIDETAVRAQMASEPRFDPKVWARLGSELGVLGMSVPESH MSMEG_6585|M.smegmatis_MC2_155 RAAVRKFGAEYFDEQTVRRLMESEPRFDPAVWARLGAELGVLGLAVPEAD TH_0804|M.thermoresistible__bu RAAVRRFCTEHFDEQTVRRLMESEPRFDPKVWARLGAELGVLGMSVPEAD MMAR_1954|M.marinum_M RASVGQLFAERCPPESVVAAYDSPPADFAKLWRTLAAELGVAGLLVPESL MUL_2176|M.ulcerans_Agy99 RASVGQLFAERCPPESVVAAYDSPPADFAKLWRTLAAELGVAGLLVPESL MAV_2570|M.avium_104 RLASEDRVRAVAYAEGNRGGGDGHSGFDTVLWDVLCNQVGVAGIALPEHL MAB_3123|M.abscessus_ATCC_1997 RSLVRSWCERVWTPKHVRQIAEAG-SVDLDAWRALGSELGVVGLSLPEQH MLBr_00737|M.leprae_Br4923 RATIRALAEKEIAP--HAADVDQRARFPEEALAALN-ASGFNAIHVPEEY * * . .: :* Mb1968c|M.bovis_AF2122/97 GGLGATLVETAIAFAELGRALTPIPFAATVF-AIEAILRMGDDEQ-RKRL Rv1933c|M.tuberculosis_H37Rv GGLGATLVETAIAFAELGRALTPIPFAATVF-AIEAILRMGDDEQ-RKRL Mflv_0345|M.gilvum_PYR-GCK GGAGGNLVDQAVAVEQLGAALACGPLFGTVYLAIPALVAASGG----QEL Mvan_0393|M.vanbaalenii_PYR-1 GGAGGTLVDQAVAVEQLGAALACGPLFGTVYLAIPALVASSQP----GDL MSMEG_6585|M.smegmatis_MC2_155 GGAGGTLVDQAVAVEELGAALACGPLIGTVYLSIPALVAASAGPV-RDEL TH_0804|M.thermoresistible__bu GGVGGTLVDQAVAVEEFGAALACGPFFGTVYLAVPALAAASAGPV-RDEL MMAR_1954|M.marinum_M GGAGASAREAAVVMEEVGRAVAPVPFLSSAVLATVALLHSGET-----ET MUL_2176|M.ulcerans_Agy99 GGAGASAREAAVVMEEVGRAVAPVPFLSSAVLATVALLHSGET-----ET MAV_2570|M.avium_104 GGAGYGVSALGVVAHELGRALAPVPFVGSTVLATGLLLDLTERDPDADKR MAB_3123|M.abscessus_ATCC_1997 GGGGLGVIELSIVAEELGRALACLPWISSAALGATALVSSGDDSA-LAEW MLBr_00737|M.leprae_Br4923 GGQGADSVAACIVIEEVARVDASASLIPAVNKLGTMGLILRGSEELKKQV ** * :. :.. . : . :. Mb1968c|M.bovis_AF2122/97 LAGLLTGARIGTIAVSGHDVASATTVRAVR---RDGRPALTGECTPVLHG Rv1933c|M.tuberculosis_H37Rv LAGLLTGARIGTIAVSGHDVASATTVRAVR---RDGRPALTGECTPVLHG Mflv_0345|M.gilvum_PYR-GCK LGPLVDGTRTAAFAVRDDAGAFDASSVEVQAVPTEQGWALSGTVERVVDA Mvan_0393|M.vanbaalenii_PYR-1 LAPLIEGIRTAAFAVPDAGGDFDADAVTVEAIPTDQGWTLTGTVQRVVDA MSMEG_6585|M.smegmatis_MC2_155 LGALVEGARTAAFAVPDRAGAFDPALVGVT---ASADATLTGTVERIVDG TH_0804|M.thermoresistible__bu LGPLLEGARTAAVILADRAGVFDPTAVTVT---TDG-ATLTGTASQVVDV MMAR_1954|M.marinum_M LSELAQGELTAALVVPLATAPGDPVAGVSR-----GSAGLSGRVCGVAGA MUL_2176|M.ulcerans_Agy99 LSELAQGELTAALVVPLATAPGDPVAGASR-----GSAGLSGRVCGVAGA MAV_2570|M.avium_104 LTGLIEGRRTAAAALTGDGGLWRRSAVTLRAARAGDDWNIDGTVRHVLGG MAB_3123|M.abscessus_ATCC_1997 VPALAAGEKTITLAG-GRTRLADAITVSAES--DTDGWKLTGDTEHVPDG MLBr_00737|M.leprae_Br4923 LPSLAAEGAMASYALSEREAGSDAASMRTRAKADGDDWILNGFKCWITNG : * : : * : Mb1968c|M.bovis_AF2122/97 HVADLFVVPAVADGS-----IVLHVVAADAPGVTVTP-LPSFDITRPVAT Rv1933c|M.tuberculosis_H37Rv HVADLFVVPAVADGS-----IVLHVVAADAPGVTVTP-LPSFDITRPVAT Mflv_0345|M.gilvum_PYR-GCK GAADVLLVAATTPDG-----VGLFVVEADSLGVQRIR-LTTLDLTRPQAT Mvan_0393|M.vanbaalenii_PYR-1 GAADVVLVAAAGPDG-----LGLYAIEADNIGVQRIP-LTTLDLTRPQAT MSMEG_6585|M.smegmatis_MC2_155 AAADVFLVAATAPDG-----VALYAVDAS--DVQRTP-LTTLDLTRPQAT TH_0804|M.thermoresistible__bu DAADDLLVAADGPDG-----VGLYAVDATGPGVTRTP-LVTMDLTRPQAA MMAR_1954|M.marinum_M READVLVVPVAGADG-----VELHTVRANAPGVEIVP-LLAFDMTRPLAD MUL_2176|M.ulcerans_Agy99 READVLVVPVAGADG-----VELHTVRANAPGVEIVP-LLAFDMTRPLAD MAV_2570|M.avium_104 SVADDLVVVAIDEDGE----PAVFLLDPTIDSVVAEA-ERVLDRTRPMAT MAB_3123|M.abscessus_ATCC_1997 ATADVILVLADTDSG-----PSLFAVDGDAPGVDRHS-LATLDMTRRQAN MLBr_00737|M.leprae_Br4923 GKSTWYTVMAVTDPDKGANGISAFIVHKDDEGFSIGPKEKKLGIKGSPTT : * . . . : .. :. . : Mb1968c|M.bovis_AF2122/97 LRLAGSP----AEPLT--AGTPDDMERVLDVARVLLAAEMLGGAEACLDL Rv1933c|M.tuberculosis_H37Rv LRLAGSP----AEPLT--AGTPDDMERVLDVARVLLAAEMLGGAEACLDL Mflv_0345|M.gilvum_PYR-GCK VGLLDAP----AQLIAGPEEAERVITHALQVGAALLAVEQVGAAQHLLDL Mvan_0393|M.vanbaalenii_PYR-1 VGLFHAP----ARLVAGPAEAERVITHALQIGAALLAVEQVGAAQHLLDL MSMEG_6585|M.smegmatis_MC2_155 IALTDTP----GRLVSGPGEAERVIGHALQVGAALLAVEQVGAAQHLLDL TH_0804|M.thermoresistible__bu VRFSGAP----ARLVAEPGTAERVITRALQVGAALLAVEQVGAAQHLLDL MMAR_1954|M.marinum_M VVFSGAA----SAPVG-LGSAEAALAEALQTGAALLASEQLGIAQWCFDT MUL_2176|M.ulcerans_Agy99 VVFSGAA----SAPVG-LGSAEAALAEALQTGAALLASEQLGIAQWCFDT MAV_2570|M.avium_104 ITLSSAP----ALRLSGDAPLGDVVDRNVDIALAVLSAEQVGACERVLEI MAB_3123|M.abscessus_ATCC_1997 IHFNSAP----ARLIGAQGRGAEAVATALDVAATVLAAEQAGIAAHMLDV MLBr_00737|M.leprae_Br4923 ELYFDKCRIPGDRIIGEPGTGFKTALATLDHTRPTIGAQAVGIAQGALDA : :: :. : * . :: Mb1968c|M.bovis_AF2122/97 AVQYAGRRTQFDRPIGSFQAVKHACADMMIEIDATRATVMFAAMSAANGD Rv1933c|M.tuberculosis_H37Rv AVQYAGRRTQFDRPIGSFQAVKHACADMMIEIDATRATVMFAAMSAANGD Mflv_0345|M.gilvum_PYR-GCK SVDYAKNRLQFGRPIGSFQAVKHRLADDLVAVEHARSTAYHAVWALSDGS Mvan_0393|M.vanbaalenii_PYR-1 TVDYAKNRLQFGRPIGSFQAVKHRLADDLVALEHARSTAYHAVWALTDGS MSMEG_6585|M.smegmatis_MC2_155 SVDYAKSRLQFGRPIGSFQAVKHRLADDLVDLEHARSAAYHAVWALADGS TH_0804|M.thermoresistible__bu SVDYAKSRLQFGRPIGSFQAVKHRLADMLVDVEHARSTAYHAVWALADPA MMAR_1954|M.marinum_M TLAYTKQRKQFGRAIGSYQAIKHRLADLWLEVGSARAAARYGADTCARGD MUL_2176|M.ulcerans_Agy99 TLAYTKQRKQFGRAIGSYQAIKHRLADLWLEVGSARAAARYGADTCARGD MAV_2570|M.avium_104 ATDYARTREQFGRQIGSFQAIKHKCADMLVDLEWARSASQAALEALDDPD MAB_3123|M.abscessus_ATCC_1997 TTEYAKSRIQFGRIIGSFQAVKHRLADMAAATGNVRGAAYHAAWSHDHPS MLBr_00737|M.leprae_Br4923 AIVYTKDRKQFGESISTFQSIQFMLADMAMKVEAARLIVYAAAARAERGE : *: * **.. *.::*:::. ** .* . Mb1968c|M.bovis_AF2122/97 -----ELQTVAPLAKAQTAETFVLCAGSALQIHGAIAFTWEHDLHLYYRR Rv1933c|M.tuberculosis_H37Rv -----ELQTVAPLAKAQTAETFVLCAGSALQIHGAIAFTWEHDLHLYYRR Mflv_0345|M.gilvum_PYR-GCK ----DDPALAVSIAQATTSAAFVRVATDTIQVHGGIGFTWEHQAHLYYKR Mvan_0393|M.vanbaalenii_PYR-1 ----DDPALAVSIAQATCSEALVRVATDTIQVHGGIGFTWEHQAHLYYKR MSMEG_6585|M.smegmatis_MC2_155 ----DDPALAASIAQATASAALTKIATDTIQVHGGIGFTWEHQAHLYFKR TH_0804|M.thermoresistible__bu GEL-DDPALATGIAQAVCSAAFSRVAADTIQVHGGIGFTWEHSAHLYYKR MMAR_1954|M.marinum_M ----EDAAIAAAIAAAYCGDVAVHAAEECVQLHGGIGMTWEYPAHLYLKR MUL_2176|M.ulcerans_Agy99 ----EDAAIAAAIAAAYCGDVAVHAAEECVQLHGGIGMTWEYPAHLYLKR MAV_2570|M.avium_104 SAAAGEAGWRASMAKAVCSEALRNATKANVQIHGGIGFTWEDSAHLYFRR MAB_3123|M.abscessus_ATCC_1997 ---LDDPALATSIAQQVASAGAVEVTAKAIQSHGGIGFTWEHPAHLYYKR MLBr_00737|M.leprae_Br4923 ----PDLGFISAASKCFASDIAMEVTTDAVQLFGGAGYTSDFPVERFMRD : : . : :* .*. . * : . : : Mb1968c|M.bovis_AF2122/97 AKTTEALFGSSARNRALLAERAGL--------------VKA--------- Rv1933c|M.tuberculosis_H37Rv AKTTEALFGSSARNRALLAERAGL--------------VKA--------- Mflv_0345|M.gilvum_PYR-GCK AYTDAALLGGAEEHRARVADFVLV-----VAPEKDAPRVATGMPS----- Mvan_0393|M.vanbaalenii_PYR-1 AYTDAALLGSAEAHRARVAELVLD-----VAPRKDAPRVATGMPS----- MSMEG_6585|M.smegmatis_MC2_155 ATTDAALLGTAEAHRDRIAELILDRAVSDQATIDRAPRVATGTN------ TH_0804|M.thermoresistible__bu AATDAALLGTAEQHRDRVAALALD-----TASPDRVPRVATGSG------ MMAR_1954|M.marinum_M AKSDQLALGTAYRHRGRLAKLVNLP-------------VS---------- MUL_2176|M.ulcerans_Agy99 AKSDQLALGTAYRHRGRLAKLVNLP-------------VS---------- MAV_2570|M.avium_104 ARTDEVLLGAPGQHWDRLSTLDPSTQPPASPEVTKELNDVDALRAEIRSF MAB_3123|M.abscessus_ATCC_1997 AVSNSALFGGRAVHAERIAKEVIDA------------------------- MLBr_00737|M.leprae_Br4923 AKITQIYEGTNQIQRVVMSRALLR-------------------------- * * : :: Mb1968c|M.bovis_AF2122/97 -------------------------------------------------- Rv1933c|M.tuberculosis_H37Rv -------------------------------------------------- Mflv_0345|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_0393|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_6585|M.smegmatis_MC2_155 -------------------------------------------------- TH_0804|M.thermoresistible__bu -------------------------------------------------- MMAR_1954|M.marinum_M -------------------------------------------------- MUL_2176|M.ulcerans_Agy99 -------------------------------------------------- MAV_2570|M.avium_104 LDNAPRPAGLRNYGPTPTADDVEAGRVWHRYLADHGYACLHWPREFGGAA MAB_3123|M.abscessus_ATCC_1997 -------------------------------------------------- MLBr_00737|M.leprae_Br4923 -------------------------------------------------- Mb1968c|M.bovis_AF2122/97 -------------------------------------------------- Rv1933c|M.tuberculosis_H37Rv -------------------------------------------------- Mflv_0345|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_0393|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_6585|M.smegmatis_MC2_155 -------------------------------------------------- TH_0804|M.thermoresistible__bu -------------------------------------------------- MMAR_1954|M.marinum_M -------------------------------------------------- MUL_2176|M.ulcerans_Agy99 -------------------------------------------------- MAV_2570|M.avium_104 ATVTYQAVFAEECARAEVPRQVNITGADLVGPVLIKFGSQEQKDRYLEPI MAB_3123|M.abscessus_ATCC_1997 -------------------------------------------------- MLBr_00737|M.leprae_Br4923 -------------------------------------------------- Mb1968c|M.bovis_AF2122/97 -------------------------------------------------- Rv1933c|M.tuberculosis_H37Rv -------------------------------------------------- Mflv_0345|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_0393|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_6585|M.smegmatis_MC2_155 -------------------------------------------------- TH_0804|M.thermoresistible__bu -------------------------------------------------- MMAR_1954|M.marinum_M -------------------------------------------------- MUL_2176|M.ulcerans_Agy99 -------------------------------------------------- MAV_2570|M.avium_104 RLGDDVWCQLFSEPGAGSDLAGVRTRAERTTTGWRIDGQKVWSSAAASAR MAB_3123|M.abscessus_ATCC_1997 -------------------------------------------------- MLBr_00737|M.leprae_Br4923 -------------------------------------------------- Mb1968c|M.bovis_AF2122/97 -------------------------------------------------- Rv1933c|M.tuberculosis_H37Rv -------------------------------------------------- Mflv_0345|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_0393|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_6585|M.smegmatis_MC2_155 -------------------------------------------------- TH_0804|M.thermoresistible__bu -------------------------------------------------- MMAR_1954|M.marinum_M -------------------------------------------------- MUL_2176|M.ulcerans_Agy99 -------------------------------------------------- MAV_2570|M.avium_104 FGLLLARTGPDKHRDLSMFVVPMDIPGVTVRPLTQMDGESKFNEVFFDGA MAB_3123|M.abscessus_ATCC_1997 -------------------------------------------------- MLBr_00737|M.leprae_Br4923 -------------------------------------------------- Mb1968c|M.bovis_AF2122/97 -------------------------------------------------- Rv1933c|M.tuberculosis_H37Rv -------------------------------------------------- Mflv_0345|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_0393|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_6585|M.smegmatis_MC2_155 -------------------------------------------------- TH_0804|M.thermoresistible__bu -------------------------------------------------- MMAR_1954|M.marinum_M -------------------------------------------------- MUL_2176|M.ulcerans_Agy99 -------------------------------------------------- MAV_2570|M.avium_104 ELDEDALIGEVGQGWTVAMVTLGRERLTLGSQAVSMFRLHERMVDAARDH MAB_3123|M.abscessus_ATCC_1997 -------------------------------------------------- MLBr_00737|M.leprae_Br4923 -------------------------------------------------- Mb1968c|M.bovis_AF2122/97 -------------------------------------------------- Rv1933c|M.tuberculosis_H37Rv -------------------------------------------------- Mflv_0345|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_0393|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_6585|M.smegmatis_MC2_155 -------------------------------------------------- TH_0804|M.thermoresistible__bu -------------------------------------------------- MMAR_1954|M.marinum_M -------------------------------------------------- MUL_2176|M.ulcerans_Agy99 -------------------------------------------------- MAV_2570|M.avium_104 DLLDPVLSRSMTRLWARMWLLRFTWQRAIDSGDLTSPAFSVLKLMTSETD MAB_3123|M.abscessus_ATCC_1997 -------------------------------------------------- MLBr_00737|M.leprae_Br4923 -------------------------------------------------- Mb1968c|M.bovis_AF2122/97 -------------------------------------------------- Rv1933c|M.tuberculosis_H37Rv -------------------------------------------------- Mflv_0345|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_0393|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_6585|M.smegmatis_MC2_155 -------------------------------------------------- TH_0804|M.thermoresistible__bu -------------------------------------------------- MMAR_1954|M.marinum_M -------------------------------------------------- MUL_2176|M.ulcerans_Agy99 -------------------------------------------------- MAV_2570|M.avium_104 QDLGDMATEVLGTDACTDPEEDGLVHHMLIGRAQTILGGTSEIQRNILGE MAB_3123|M.abscessus_ATCC_1997 -------------------------------------------------- MLBr_00737|M.leprae_Br4923 -------------------------------------------------- Mb1968c|M.bovis_AF2122/97 ---------- Rv1933c|M.tuberculosis_H37Rv ---------- Mflv_0345|M.gilvum_PYR-GCK ---------- Mvan_0393|M.vanbaalenii_PYR-1 ---------- MSMEG_6585|M.smegmatis_MC2_155 ---------- TH_0804|M.thermoresistible__bu ---------- MMAR_1954|M.marinum_M ---------- MUL_2176|M.ulcerans_Agy99 ---------- MAV_2570|M.avium_104 RVLGLPKEPR MAB_3123|M.abscessus_ATCC_1997 ---------- MLBr_00737|M.leprae_Br4923 ----------