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M. thermoresistible (build 8) TH_2456 (-)

annotation: putative acyl-CoA dehydrogenase domain protein
coordinates: 1176375 - 1177415
length: 347

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_2456--100% (347)putative acyl-CoA dehydrogenase domain protein
M. thermoresistible (build 8)TH_4038-1e-9151.75% (342) PUTATIVE putative acyl-CoA dehydrogenase domain protein
M. thermoresistible (build 8)TH_0804-2e-8148.10% (343) acyl-CoA dehydrogenase

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb1968cfadE186e-6141.12% (338) acyl-CoA dehydrogenase FADE18
M. gilvum PYR-GCKMflv_0345-4e-7946.63% (341) acyl-CoA dehydrogenase domain-containing protein
M. tuberculosis H37RvRv1933cfadE186e-6141.12% (338) acyl-CoA dehydrogenase FADE18
M. leprae Br4923MLBr_00737fadE251e-2529.65% (317) putative acyl-CoA dehydrogenase
M. abscessus ATCC 19977MAB_3123-1e-7345.59% (329) putative acyl-CoA dehydrogenase
M. marinum MMMAR_2861fadE181e-6342.81% (334) acyl-CoA dehydrogenase FadE18
M. avium 104MAV_1838-3e-5939.81% (324) acyl-CoA dehydrogenase protein
M. smegmatis MC2 155MSMEG_6585-1e-7848.09% (341) acyl-CoA dehydrogenase
M. ulcerans Agy99MUL_2176fadE18_11e-6342.77% (339) acyl-CoA dehydrogenase FadE18_1
M. vanbaalenii PYR-1Mvan_0393-5e-7947.21% (341) acyl-CoA dehydrogenase domain-containing protein

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_0345|M.gilvum_PYR-GCK          --------------------------MAD-----TAG-EWVFSDEQNQLR
Mvan_0393|M.vanbaalenii_PYR-1       --------------------------MAD-----SQGAEYVFTEEQGQLR
MSMEG_6585|M.smegmatis_MC2_155      MAEELVDQPDKVAEELVDQPDKVAEELVDQPDKVAETTEFRFTDEQGQLR
TH_2456|M.thermoresistible__bu      --------------------------------------------------
MUL_2176|M.ulcerans_Agy99           ----------------------------------MSTGDLLYSDTEEALR
Mb1968c|M.bovis_AF2122/97           -------------------------------------MDFRYSTEQDDFR
Rv1933c|M.tuberculosis_H37Rv        -------------------------------------MDFRYSTEQDDFR
MMAR_2861|M.marinum_M               -------------------------------------MDFRYSTEQDDFR
MAV_1838|M.avium_104                -------------------------------------MTGLSLDESRELA
MAB_3123|M.abscessus_ATCC_1997      ------MSASEDHQTRMSASEDNQTRMSASEDNQAQINEFEFTEEHGDLR
MLBr_00737|M.leprae_Br4923          ---------------------------MVGWSGNPLFDLFKLPEEHNELR
                                                                                      

Mflv_0345|M.gilvum_PYR-GCK          AAVRAFCADHVDESSVRAAMESDPP----FDAKVWSRLGSELGVLGMAVP
Mvan_0393|M.vanbaalenii_PYR-1       AAVRRFCADHIDETAVRAQMASEPR----FDPKVWARLGSELGVLGMSVP
MSMEG_6585|M.smegmatis_MC2_155      AAVRKFGAEYFDEQTVRRLMESEPR----FDPAVWARLGAELGVLGLAVP
TH_2456|M.thermoresistible__bu      ---------------VRTVMDSPPG----YDSRVWRALAAELGVLGVAVP
MUL_2176|M.ulcerans_Agy99           ASVGQLFAERCPPESVVAAYDSPPA----DFAKLWRTLAAELGVAGLLVP
Mb1968c|M.bovis_AF2122/97           ASLRGFLGRGAP---VREMAAADG-----SDRRLWQRLCTELELPALHVP
Rv1933c|M.tuberculosis_H37Rv        ASLRGFLGRGAP---VREMAAADG-----SDRRLWQRLCTELELPALHVP
MMAR_2861|M.marinum_M               ESLRGFLRDQAPPARVRQVAAVGG-----HDKKLWHRLCAELELPALHAP
MAV_1838|M.avium_104                RSVRAACERFAPEERVRAIAYNGGGVDAGFDTELWKVLCAQVGVAAIGMP
MAB_3123|M.abscessus_ATCC_1997      SLVRSWCERVWTPKHVRQIAEAGS-----VDLDAWRALGSELGVVGLSLP
MLBr_00737|M.leprae_Br4923          ATIRALAEKEIAPHAADVDQRARFP------EEALAALNAS-GFNAIHVP
                                                   .                     * :.  . .:  *

Mflv_0345|M.gilvum_PYR-GCK          ESAGGAGGNLVDQAVAVEQLGAALACGPLFGTVYLAIPALVAA-SGG---
Mvan_0393|M.vanbaalenii_PYR-1       ESHGGAGGTLVDQAVAVEQLGAALACGPLFGTVYLAIPALVAS-SQP---
MSMEG_6585|M.smegmatis_MC2_155      EADGGAGGTLVDQAVAVEELGAALACGPLIGTVYLSIPALVAA-SAGPVR
TH_2456|M.thermoresistible__bu      DEFGGAGAGMRELAVVFEETGAALLCAPLYATAGLAIPALLAS-GDREAM
MUL_2176|M.ulcerans_Agy99           ESLGGAGASAREAAVVMEEVGRAVAPVPFLSSAVLATVALLHS-GET---
Mb1968c|M.bovis_AF2122/97           PEHGGLGATLVETAIAFAELGRALTPIPFAATVFAIEAILRMG--DDEQR
Rv1933c|M.tuberculosis_H37Rv        PEHGGLGATLVETAIAFAELGRALTPIPFAATVFAIEAILRMG--DDEQR
MMAR_2861|M.marinum_M               PEYGGAGGTLVETAIAFGELGRALTPVPFAATILAIEAILRMG--DSEQR
MAV_1838|M.avium_104                EDLGGAGFDATALGVVAHELGRALAPVPFVASAVLATGLLLATRESDPDS
MAB_3123|M.abscessus_ATCC_1997      EQHGGGGLGVIELSIVAEELGRALACLPWISSAALGATALVSS-GDDSAL
MLBr_00737|M.leprae_Br4923          EEYGGQGADSVAACIVIEEVARVDASASLIPAVNKLGTMGLILRGSEELK
                                       ** *       :.  : . .    .   :                  

Mflv_0345|M.gilvum_PYR-GCK          QELLGPLVDGTRTAAFAVRDDAGAFDASSVEVQAVPTEQG-WALSGTVER
Mvan_0393|M.vanbaalenii_PYR-1       GDLLAPLIEGIRTAAFAVPDAGGDFDADAVTVEAIPTDQG-WTLTGTVQR
MSMEG_6585|M.smegmatis_MC2_155      DELLGALVEGARTAAFAVPDRAGAFDPALVGVTASADAT----LTGTVER
TH_2456|M.thermoresistible__bu      ADLLPGVVDGSTIATVVFNDALTAWDPAAVTLTAHRTADG-HRVNGSAAT
MUL_2176|M.ulcerans_Agy99           -ETLSELAQGELTAALVVPLATAPGDPVAG---ASRGSAG---LSGRVCG
Mb1968c|M.bovis_AF2122/97           KRLLAGLLTGARIGTIAVSG----HDVASATTVRAVRRDGRPALTGECTP
Rv1933c|M.tuberculosis_H37Rv        KRLLAGLLTGARIGTIAVSG----HDVASATTVRAVRRDGRPALTGECTP
MMAR_2861|M.marinum_M               KGLLSGLLSGDRIGALAAAG----PDLS-VTSVRAGRRDGRPVLTGECAP
MAV_1838|M.avium_104                EQRLSGLMEGHRTAAAAVTGDGGLWQRDSVTLVANANIDG-WAVNGTVRH
MAB_3123|M.abscessus_ATCC_1997      AEWVPALAAGEKTITLAGGR---TRLADAITVSAESDTDG-WKLTGDTEH
MLBr_00737|M.leprae_Br4923          KQVLPSLAAEGAMASYALSEREAGSDAASMRTRAKADGDD-WILNGFKCW
                                       :  :       : .                          :.*    

Mflv_0345|M.gilvum_PYR-GCK          VVDAGAADVLLVAATTP-----DGVGLFVVEADSLGVQRIRLTTLDLTR-
Mvan_0393|M.vanbaalenii_PYR-1       VVDAGAADVVLVAAAGP-----DGLGLYAIEADNIGVQRIPLTTLDLTR-
MSMEG_6585|M.smegmatis_MC2_155      IVDGAAADVFLVAATAP-----DGVALYAVDAS--DVQRTPLTTLDLTR-
TH_2456|M.thermoresistible__bu      VLDGHNADLILVAARTG-----AGLSLLAVRADAPGLDRRPLAGLDRTR-
MUL_2176|M.ulcerans_Agy99           VAGAREADVLVVPVAGA-----DGVELHTVRANAPGVEIVPLLAFDMTR-
Mb1968c|M.bovis_AF2122/97           VLHGHVADLFVVPAVAD-----GSIVLHVVAADAPGVTVTPLPSFDITR-
Rv1933c|M.tuberculosis_H37Rv        VLHGHVADLFVVPAVAD-----GSIVLHVVAADAPGVTVTPLPSFDITR-
MMAR_2861|M.marinum_M               VLHGHVADLFVVPAESD-----GAVILYVVDAAAPGVAVVGLPSFDITR-
MAV_1838|M.avium_104                VLNGCAANDLVVVAKAD-----DQPALFLIDPMAEGVAVEAERVLDGTR-
MAB_3123|M.abscessus_ATCC_1997      VPDGATADVILVLADTD-----SGPSLFAVDGDAPGVDRHSLATLDMTR-
MLBr_00737|M.leprae_Br4923          ITNGGKSTWYTVMAVTDPDKGANGISAFIVHKDDEGFSIGPKEKKLGIKG
                                    :  .  :    * .               :     ..           : 

Mflv_0345|M.gilvum_PYR-GCK          -PQATVGLLDA---PAQLIAGPEEAERVITHALQVGAALLAVEQVGAAQH
Mvan_0393|M.vanbaalenii_PYR-1       -PQATVGLFHA---PARLVAGPAEAERVITHALQIGAALLAVEQVGAAQH
MSMEG_6585|M.smegmatis_MC2_155      -PQATIALTDT---PGRLVSGPGEAERVIGHALQVGAALLAVEQVGAAQH
TH_2456|M.thermoresistible__bu      -RTARLRFDDV---PARLIGADGAAEPWLARTYQLGLTALAAEQVGGAQR
MUL_2176|M.ulcerans_Agy99           -PLADVVFSGA---ASAPVG-LGSAEAALAEALQTGAALLASEQLGIAQW
Mb1968c|M.bovis_AF2122/97           -PVATLRLAGS---PAEPLTAGTPDD--MERVLDVARVLLAAEMLGGAEA
Rv1933c|M.tuberculosis_H37Rv        -PVATLRLAGS---PAEPLTAGTPDD--MERVLDVARVLLAAEMLGGAEA
MMAR_2861|M.marinum_M               -PVAKLRLVRA---PAEALAASSADE--VARLLDVARVLLAAEMLGGAEA
MAV_1838|M.avium_104                -PMATITFTGA---TALKLTGREAVDTIIEHNIDVALAVLSAEQVGACER
MAB_3123|M.abscessus_ATCC_1997      -RQANIHFNSA---PARLIGAQGRGAEAVATALDVAATVLAAEQAGIAAH
MLBr_00737|M.leprae_Br4923          SPTTELYFDKCRIPGDRIIGEPGTGFKTALATLDHTRPTIGAQAVGIAQG
                                       : : :          :              :     :. :  * .  

Mflv_0345|M.gilvum_PYR-GCK          LLDLSVDYAKNRLQFGRPIGSFQAVKHRLADDLVAVEHARSTAYHAVWAL
Mvan_0393|M.vanbaalenii_PYR-1       LLDLTVDYAKNRLQFGRPIGSFQAVKHRLADDLVALEHARSTAYHAVWAL
MSMEG_6585|M.smegmatis_MC2_155      LLDLSVDYAKSRLQFGRPIGSFQAVKHRLADDLVDLEHARSAAYHAVWAL
TH_2456|M.thermoresistible__bu      CLDMAVDYAKHRIQFGRPIGSFQAVKHRCADMLVAVEGARSAAVHAAEAA
MUL_2176|M.ulcerans_Agy99           CFDTTLAYTKQRKQFGRAIGSYQAIKHRLADLWLEVGSARAAARYGADTC
Mb1968c|M.bovis_AF2122/97           CLDLAVQYAGRRTQFDRPIGSFQAVKHACADMMIEIDATRATVMFAAMSA
Rv1933c|M.tuberculosis_H37Rv        CLDLAVQYAGRRTQFDRPIGSFQAVKHACADMMIEIDATRATVMFAAMSA
MMAR_2861|M.marinum_M               CLDLAIEYACSRKQFDRPIGSFQAVKHRCADMMIEIDATRAAVMFAQLCA
MAV_1838|M.avium_104                VLEIACEYARTREQFGRPIGSFQAIKHKCADMLVDLEWARSASQAALEAV
MAB_3123|M.abscessus_ATCC_1997      MLDVTTEYAKSRIQFGRIIGSFQAVKHRLADMAAATGNVRGAAYHAAWSH
MLBr_00737|M.leprae_Br4923          ALDAAIVYTKDRKQFGESISTFQSIQFMLADMAMKVEAARLIVYAAAARA
                                     :: :  *:  * **.. *.::*:::.  **       .*     .    

Mflv_0345|M.gilvum_PYR-GCK          SDGS-DDPALAVSIAQATTSAAFVRVATDTIQVHGGIGFTWEHQAHLYYK
Mvan_0393|M.vanbaalenii_PYR-1       TDGS-DDPALAVSIAQATCSEALVRVATDTIQVHGGIGFTWEHQAHLYYK
MSMEG_6585|M.smegmatis_MC2_155      ADGS-DDPALAASIAQATASAALTKIATDTIQVHGGIGFTWEHQAHLYFK
TH_2456|M.thermoresistible__bu      -DGH-GDLPTAAAVAKMVCSDAYLQAALDNLRIHGGIGFTWEHDAHLYVR
MUL_2176|M.ulcerans_Agy99           ARGD-EDAAIAAAIAAAYCGDVAVHAAEECVQLHGGIGMTWEYPAHLYLK
Mb1968c|M.bovis_AF2122/97           ANGD-ELQTVAP-LAKAQTAETFVLCAGSALQIHGAIAFTWEHDLHLYYR
Rv1933c|M.tuberculosis_H37Rv        ANGD-ELQTVAP-LAKAQTAETFVLCAGSALQIHGAIAFTWEHDLHLYYR
MMAR_2861|M.marinum_M               AGGD-ELHATAP-LAKAQAADTYVLCAGSAIQVHGGIAFTWEHDLHLYFR
MAV_1838|M.avium_104                VSG--ERDWRAS-MAKAVCSESLRNAAHANVQIHGGIGFTWEDSAHLYLR
MAB_3123|M.abscessus_ATCC_1997      DHPSLDDPALATSIAQQVASAGAVEVTAKAIQSHGGIGFTWEHPAHLYYK
MLBr_00737|M.leprae_Br4923          ERGE-PDLGFISAASKCFASDIAMEVTTDAVQLFGGAGYTSDFPVERFMR
                                                  :    .      :   :: .*. . * :   . : :

Mflv_0345|M.gilvum_PYR-GCK          RAYTDAALLGGAEEHRARVADFVLVVAPEKD-----APRVATGMPS
Mvan_0393|M.vanbaalenii_PYR-1       RAYTDAALLGSAEAHRARVAELVLDVAPRKD-----APRVATGMPS
MSMEG_6585|M.smegmatis_MC2_155      RATTDAALLGTAEAHRDRIAELILDRAVSDQATIDRAPRVATGTN-
TH_2456|M.thermoresistible__bu      RAKAAQLMFGGPDLHAQHLAELIGTPGKS-----------------
MUL_2176|M.ulcerans_Agy99           RAKSDQLALGTAYRHRGRLAKLVNLPVS------------------
Mb1968c|M.bovis_AF2122/97           RAKTTEALFGSSARNRALLAERAGLVKA------------------
Rv1933c|M.tuberculosis_H37Rv        RAKTTEALFGSSARNRALLAERAGLVKA------------------
MMAR_2861|M.marinum_M               RAKTTEALFGSSAHHRSLLADRVGL---------------------
MAV_1838|M.avium_104                RARTDEVLLGGPGQHWDRVGLRVL----------------------
MAB_3123|M.abscessus_ATCC_1997      RAVSNSALFGGRAVHAERIAKEVIDA--------------------
MLBr_00737|M.leprae_Br4923          DAKITQIYEGTNQIQRVVMSRALLR---------------------
                                     *       *    :   :.