For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
aa seq not available
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. thermoresistible (build 8) | TH_0804 | - | - | 100% (413) | acyl-CoA dehydrogenase |
| M. thermoresistible (build 8) | TH_2456 | - | 2e-81 | 48.10% (343) | PUTATIVE putative acyl-CoA dehydrogenase domain protein |
| M. thermoresistible (build 8) | TH_4038 | - | 3e-77 | 42.15% (382) | PUTATIVE putative acyl-CoA dehydrogenase domain protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1968c | fadE18 | 2e-57 | 38.21% (369) | acyl-CoA dehydrogenase FADE18 |
| M. gilvum PYR-GCK | Mflv_0345 | - | 1e-143 | 70.13% (385) | acyl-CoA dehydrogenase domain-containing protein |
| M. tuberculosis H37Rv | Rv1933c | fadE18 | 2e-57 | 38.21% (369) | acyl-CoA dehydrogenase FADE18 |
| M. leprae Br4923 | MLBr_00737 | fadE25 | 4e-19 | 23.66% (393) | putative acyl-CoA dehydrogenase |
| M. abscessus ATCC 19977 | MAB_3123 | - | 5e-83 | 44.30% (395) | putative acyl-CoA dehydrogenase |
| M. marinum M | MMAR_1954 | fadE18_1 | 1e-66 | 42.58% (364) | acyl-CoA dehydrogenase FadE18_1 |
| M. avium 104 | MAV_2570 | - | 8e-64 | 38.80% (384) | putative acyl-CoA dehydrogenase |
| M. smegmatis MC2 155 | MSMEG_6585 | - | 1e-166 | 73.86% (417) | acyl-CoA dehydrogenase |
| M. ulcerans Agy99 | MUL_2176 | fadE18_1 | 2e-66 | 42.31% (364) | acyl-CoA dehydrogenase FadE18_1 |
| M. vanbaalenii PYR-1 | Mvan_0393 | - | 1e-149 | 72.47% (385) | acyl-CoA dehydrogenase domain-containing protein |
CLUSTAL 2.0.9 multiple sequence alignment
TH_0804|M.thermoresistible__bu -----------VAEELAEQPDNAAEELAEQPDNAAGLSPTFTFTEEQQQL
MSMEG_6585|M.smegmatis_MC2_155 MAEELVDQPDKVAEELVDQPDKVAEELVDQPDKVAETT-EFRFTDEQGQL
Mflv_0345|M.gilvum_PYR-GCK --------------------------------MADTAG-EWVFSDEQNQL
Mvan_0393|M.vanbaalenii_PYR-1 --------------------------------MADSQGAEYVFTEEQGQL
MMAR_1954|M.marinum_M -----------------------------------MSTGDLLYSDTEEAL
MUL_2176|M.ulcerans_Agy99 -----------------------------------MSTGDLLYSDTEEAL
Mb1968c|M.bovis_AF2122/97 --------------------------------------MDFRYSTEQDDF
Rv1933c|M.tuberculosis_H37Rv --------------------------------------MDFRYSTEQDDF
MAV_2570|M.avium_104 -----------------------------MTALSADERQELAQSVRSACE
MAB_3123|M.abscessus_ATCC_1997 -------MSASEDHQTRMSASEDNQTRMSASEDNQAQINEFEFTEEHGDL
MLBr_00737|M.leprae_Br4923 ----------------------------MVGWSGNPLFDLFKLPEEHNEL
.
TH_0804|M.thermoresistible__bu RAAVRRFCTEHFDEQTVRRLMESEPRFDPKVWARLGAELGVLGMSVPEAD
MSMEG_6585|M.smegmatis_MC2_155 RAAVRKFGAEYFDEQTVRRLMESEPRFDPAVWARLGAELGVLGLAVPEAD
Mflv_0345|M.gilvum_PYR-GCK RAAVRAFCADHVDESSVRAAMESDPPFDAKVWSRLGSELGVLGMAVPESA
Mvan_0393|M.vanbaalenii_PYR-1 RAAVRRFCADHIDETAVRAQMASEPRFDPKVWARLGSELGVLGMSVPESH
MMAR_1954|M.marinum_M RASVGQLFAERCPPESVVAAYDSPPADFAKLWRTLAAELGVAGLLVPESL
MUL_2176|M.ulcerans_Agy99 RASVGQLFAERCPPESVVAAYDSPPADFAKLWRTLAAELGVAGLLVPESL
Mb1968c|M.bovis_AF2122/97 RASLRGFLGRGAPVREMAAADGS----DRRLWQRLCTELELPALHVPPEH
Rv1933c|M.tuberculosis_H37Rv RASLRGFLGRGAPVREMAAADGS----DRRLWQRLCTELELPALHVPPEH
MAV_2570|M.avium_104 RLASEDRVRAVAYAEGNRGGGDGHSGFDTVLWDVLCNQVGVAGIALPEHL
MAB_3123|M.abscessus_ATCC_1997 RSLVRSWCERVWTPKHVRQIAEAG-SVDLDAWRALGSELGVVGLSLPEQH
MLBr_00737|M.leprae_Br4923 RATIRALAEKEIAP--HAADVDQRARFPEEALAALN-ASGFNAIHVPEEY
* * . .: :*
TH_0804|M.thermoresistible__bu GGVGGTLVDQAVAVEEFGAALACGPFFGTVYLAVPALAAASAGPV-RDEL
MSMEG_6585|M.smegmatis_MC2_155 GGAGGTLVDQAVAVEELGAALACGPLIGTVYLSIPALVAASAGPV-RDEL
Mflv_0345|M.gilvum_PYR-GCK GGAGGNLVDQAVAVEQLGAALACGPLFGTVYLAIPALVAASGG----QEL
Mvan_0393|M.vanbaalenii_PYR-1 GGAGGTLVDQAVAVEQLGAALACGPLFGTVYLAIPALVASSQP----GDL
MMAR_1954|M.marinum_M GGAGASAREAAVVMEEVGRAVAPVPFLSSAVLATVALLHSGET-----ET
MUL_2176|M.ulcerans_Agy99 GGAGASAREAAVVMEEVGRAVAPVPFLSSAVLATVALLHSGET-----ET
Mb1968c|M.bovis_AF2122/97 GGLGATLVETAIAFAELGRALTPIPFAATVF-AIEAILRMGDDEQ-RKRL
Rv1933c|M.tuberculosis_H37Rv GGLGATLVETAIAFAELGRALTPIPFAATVF-AIEAILRMGDDEQ-RKRL
MAV_2570|M.avium_104 GGAGYGVSALGVVAHELGRALAPVPFVGSTVLATGLLLDLTERDPDADKR
MAB_3123|M.abscessus_ATCC_1997 GGGGLGVIELSIVAEELGRALACLPWISSAALGATALVSSGDDSA-LAEW
MLBr_00737|M.leprae_Br4923 GGQGADSVAACIVIEEVARVDASASLIPAVNKLGTMGLILRGSEELKKQV
** * :. :.. . : . :.
TH_0804|M.thermoresistible__bu LGPLLEGARTAAVILADRAGVFDPTAVTVT---TDG-ATLTGTASQVVDV
MSMEG_6585|M.smegmatis_MC2_155 LGALVEGARTAAFAVPDRAGAFDPALVGVT---ASADATLTGTVERIVDG
Mflv_0345|M.gilvum_PYR-GCK LGPLVDGTRTAAFAVRDDAGAFDASSVEVQAVPTEQGWALSGTVERVVDA
Mvan_0393|M.vanbaalenii_PYR-1 LAPLIEGIRTAAFAVPDAGGDFDADAVTVEAIPTDQGWTLTGTVQRVVDA
MMAR_1954|M.marinum_M LSELAQGELTAALVVPLATAPGDPVAGVSR-----GSAGLSGRVCGVAGA
MUL_2176|M.ulcerans_Agy99 LSELAQGELTAALVVPLATAPGDPVAGASR-----GSAGLSGRVCGVAGA
Mb1968c|M.bovis_AF2122/97 LAGLLTGARIGTIAVSGHDVASATTVRAVR---RDGRPALTGECTPVLHG
Rv1933c|M.tuberculosis_H37Rv LAGLLTGARIGTIAVSGHDVASATTVRAVR---RDGRPALTGECTPVLHG
MAV_2570|M.avium_104 LTGLIEGRRTAAAALTGDGGLWRRSAVTLRAARAGDDWNIDGTVRHVLGG
MAB_3123|M.abscessus_ATCC_1997 VPALAAGEKTITLAG-GRTRLADAITVSAES--DTDGWKLTGDTEHVPDG
MLBr_00737|M.leprae_Br4923 LPSLAAEGAMASYALSEREAGSDAASMRTRAKADGDDWILNGFKCWITNG
: * : : * :
TH_0804|M.thermoresistible__bu DAADDLLVAADGPDG-----VGLYAVDATGPGVTRTP-LVTMDLTRPQAA
MSMEG_6585|M.smegmatis_MC2_155 AAADVFLVAATAPDG-----VALYAVDAS--DVQRTP-LTTLDLTRPQAT
Mflv_0345|M.gilvum_PYR-GCK GAADVLLVAATTPDG-----VGLFVVEADSLGVQRIR-LTTLDLTRPQAT
Mvan_0393|M.vanbaalenii_PYR-1 GAADVVLVAAAGPDG-----LGLYAIEADNIGVQRIP-LTTLDLTRPQAT
MMAR_1954|M.marinum_M READVLVVPVAGADG-----VELHTVRANAPGVEIVP-LLAFDMTRPLAD
MUL_2176|M.ulcerans_Agy99 READVLVVPVAGADG-----VELHTVRANAPGVEIVP-LLAFDMTRPLAD
Mb1968c|M.bovis_AF2122/97 HVADLFVVPAVADGS-----IVLHVVAADAPGVTVTP-LPSFDITRPVAT
Rv1933c|M.tuberculosis_H37Rv HVADLFVVPAVADGS-----IVLHVVAADAPGVTVTP-LPSFDITRPVAT
MAV_2570|M.avium_104 SVADDLVVVAIDEDGE----PAVFLLDPTIDSVVAEA-ERVLDRTRPMAT
MAB_3123|M.abscessus_ATCC_1997 ATADVILVLADTDSG-----PSLFAVDGDAPGVDRHS-LATLDMTRRQAN
MLBr_00737|M.leprae_Br4923 GKSTWYTVMAVTDPDKGANGISAFIVHKDDEGFSIGPKEKKLGIKGSPTT
: * . . . : .. :. . :
TH_0804|M.thermoresistible__bu VRFSGAP----ARLVAEPGTAERVITRALQVGAALLAVEQVGAAQHLLDL
MSMEG_6585|M.smegmatis_MC2_155 IALTDTP----GRLVSGPGEAERVIGHALQVGAALLAVEQVGAAQHLLDL
Mflv_0345|M.gilvum_PYR-GCK VGLLDAP----AQLIAGPEEAERVITHALQVGAALLAVEQVGAAQHLLDL
Mvan_0393|M.vanbaalenii_PYR-1 VGLFHAP----ARLVAGPAEAERVITHALQIGAALLAVEQVGAAQHLLDL
MMAR_1954|M.marinum_M VVFSGAA----SAPVG-LGSAEAALAEALQTGAALLASEQLGIAQWCFDT
MUL_2176|M.ulcerans_Agy99 VVFSGAA----SAPVG-LGSAEAALAEALQTGAALLASEQLGIAQWCFDT
Mb1968c|M.bovis_AF2122/97 LRLAGSP----AEPLT--AGTPDDMERVLDVARVLLAAEMLGGAEACLDL
Rv1933c|M.tuberculosis_H37Rv LRLAGSP----AEPLT--AGTPDDMERVLDVARVLLAAEMLGGAEACLDL
MAV_2570|M.avium_104 ITLSSAP----ALRLSGDAPLGDVVDRNVDIALAVLSAEQVGACERVLEI
MAB_3123|M.abscessus_ATCC_1997 IHFNSAP----ARLIGAQGRGAEAVATALDVAATVLAAEQAGIAAHMLDV
MLBr_00737|M.leprae_Br4923 ELYFDKCRIPGDRIIGEPGTGFKTALATLDHTRPTIGAQAVGIAQGALDA
: :: :. : * . ::
TH_0804|M.thermoresistible__bu SVDYAKSRLQFGRPIGSFQAVKHRLADMLVDVEHARSTAYHAVWALADPA
MSMEG_6585|M.smegmatis_MC2_155 SVDYAKSRLQFGRPIGSFQAVKHRLADDLVDLEHARSAAYHAVWALADGS
Mflv_0345|M.gilvum_PYR-GCK SVDYAKNRLQFGRPIGSFQAVKHRLADDLVAVEHARSTAYHAVWALSDGS
Mvan_0393|M.vanbaalenii_PYR-1 TVDYAKNRLQFGRPIGSFQAVKHRLADDLVALEHARSTAYHAVWALTDGS
MMAR_1954|M.marinum_M TLAYTKQRKQFGRAIGSYQAIKHRLADLWLEVGSARAAARYGADTCARGD
MUL_2176|M.ulcerans_Agy99 TLAYTKQRKQFGRAIGSYQAIKHRLADLWLEVGSARAAARYGADTCARGD
Mb1968c|M.bovis_AF2122/97 AVQYAGRRTQFDRPIGSFQAVKHACADMMIEIDATRATVMFAAMSAANGD
Rv1933c|M.tuberculosis_H37Rv AVQYAGRRTQFDRPIGSFQAVKHACADMMIEIDATRATVMFAAMSAANGD
MAV_2570|M.avium_104 ATDYARTREQFGRQIGSFQAIKHKCADMLVDLEWARSASQAALEALDDPD
MAB_3123|M.abscessus_ATCC_1997 TTEYAKSRIQFGRIIGSFQAVKHRLADMAAATGNVRGAAYHAAWSHDHPS
MLBr_00737|M.leprae_Br4923 AIVYTKDRKQFGESISTFQSIQFMLADMAMKVEAARLIVYAAAARAERGE
: *: * **.. *.::*:::. ** .* .
TH_0804|M.thermoresistible__bu GEL-DDPALATGIAQAVCSAAFSRVAADTIQVHGGIGFTWEHSAHLYYKR
MSMEG_6585|M.smegmatis_MC2_155 ----DDPALAASIAQATASAALTKIATDTIQVHGGIGFTWEHQAHLYFKR
Mflv_0345|M.gilvum_PYR-GCK ----DDPALAVSIAQATTSAAFVRVATDTIQVHGGIGFTWEHQAHLYYKR
Mvan_0393|M.vanbaalenii_PYR-1 ----DDPALAVSIAQATCSEALVRVATDTIQVHGGIGFTWEHQAHLYYKR
MMAR_1954|M.marinum_M ----EDAAIAAAIAAAYCGDVAVHAAEECVQLHGGIGMTWEYPAHLYLKR
MUL_2176|M.ulcerans_Agy99 ----EDAAIAAAIAAAYCGDVAVHAAEECVQLHGGIGMTWEYPAHLYLKR
Mb1968c|M.bovis_AF2122/97 -----ELQTVAPLAKAQTAETFVLCAGSALQIHGAIAFTWEHDLHLYYRR
Rv1933c|M.tuberculosis_H37Rv -----ELQTVAPLAKAQTAETFVLCAGSALQIHGAIAFTWEHDLHLYYRR
MAV_2570|M.avium_104 SAAAGEAGWRASMAKAVCSEALRNATKANVQIHGGIGFTWEDSAHLYFRR
MAB_3123|M.abscessus_ATCC_1997 ---LDDPALATSIAQQVASAGAVEVTAKAIQSHGGIGFTWEHPAHLYYKR
MLBr_00737|M.leprae_Br4923 ----PDLGFISAASKCFASDIAMEVTTDAVQLFGGAGYTSDFPVERFMRD
: : . : :* .*. . * : . : :
TH_0804|M.thermoresistible__bu AATDAALLGTAEQHRDRVAALALD-----TASPDRVPRVATGSG------
MSMEG_6585|M.smegmatis_MC2_155 ATTDAALLGTAEAHRDRIAELILDRAVSDQATIDRAPRVATGTN------
Mflv_0345|M.gilvum_PYR-GCK AYTDAALLGGAEEHRARVADFVLV-----VAPEKDAPRVATGMPS-----
Mvan_0393|M.vanbaalenii_PYR-1 AYTDAALLGSAEAHRARVAELVLD-----VAPRKDAPRVATGMPS-----
MMAR_1954|M.marinum_M AKSDQLALGTAYRHRGRLAKLVNLP-------------VS----------
MUL_2176|M.ulcerans_Agy99 AKSDQLALGTAYRHRGRLAKLVNLP-------------VS----------
Mb1968c|M.bovis_AF2122/97 AKTTEALFGSSARNRALLAERAGL--------------VKA---------
Rv1933c|M.tuberculosis_H37Rv AKTTEALFGSSARNRALLAERAGL--------------VKA---------
MAV_2570|M.avium_104 ARTDEVLLGAPGQHWDRLSTLDPSTQPPASPEVTKELNDVDALRAEIRSF
MAB_3123|M.abscessus_ATCC_1997 AVSNSALFGGRAVHAERIAKEVIDA-------------------------
MLBr_00737|M.leprae_Br4923 AKITQIYEGTNQIQRVVMSRALLR--------------------------
* * : ::
TH_0804|M.thermoresistible__bu --------------------------------------------------
MSMEG_6585|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_0345|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_0393|M.vanbaalenii_PYR-1 --------------------------------------------------
MMAR_1954|M.marinum_M --------------------------------------------------
MUL_2176|M.ulcerans_Agy99 --------------------------------------------------
Mb1968c|M.bovis_AF2122/97 --------------------------------------------------
Rv1933c|M.tuberculosis_H37Rv --------------------------------------------------
MAV_2570|M.avium_104 LDNAPRPAGLRNYGPTPTADDVEAGRVWHRYLADHGYACLHWPREFGGAA
MAB_3123|M.abscessus_ATCC_1997 --------------------------------------------------
MLBr_00737|M.leprae_Br4923 --------------------------------------------------
TH_0804|M.thermoresistible__bu --------------------------------------------------
MSMEG_6585|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_0345|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_0393|M.vanbaalenii_PYR-1 --------------------------------------------------
MMAR_1954|M.marinum_M --------------------------------------------------
MUL_2176|M.ulcerans_Agy99 --------------------------------------------------
Mb1968c|M.bovis_AF2122/97 --------------------------------------------------
Rv1933c|M.tuberculosis_H37Rv --------------------------------------------------
MAV_2570|M.avium_104 ATVTYQAVFAEECARAEVPRQVNITGADLVGPVLIKFGSQEQKDRYLEPI
MAB_3123|M.abscessus_ATCC_1997 --------------------------------------------------
MLBr_00737|M.leprae_Br4923 --------------------------------------------------
TH_0804|M.thermoresistible__bu --------------------------------------------------
MSMEG_6585|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_0345|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_0393|M.vanbaalenii_PYR-1 --------------------------------------------------
MMAR_1954|M.marinum_M --------------------------------------------------
MUL_2176|M.ulcerans_Agy99 --------------------------------------------------
Mb1968c|M.bovis_AF2122/97 --------------------------------------------------
Rv1933c|M.tuberculosis_H37Rv --------------------------------------------------
MAV_2570|M.avium_104 RLGDDVWCQLFSEPGAGSDLAGVRTRAERTTTGWRIDGQKVWSSAAASAR
MAB_3123|M.abscessus_ATCC_1997 --------------------------------------------------
MLBr_00737|M.leprae_Br4923 --------------------------------------------------
TH_0804|M.thermoresistible__bu --------------------------------------------------
MSMEG_6585|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_0345|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_0393|M.vanbaalenii_PYR-1 --------------------------------------------------
MMAR_1954|M.marinum_M --------------------------------------------------
MUL_2176|M.ulcerans_Agy99 --------------------------------------------------
Mb1968c|M.bovis_AF2122/97 --------------------------------------------------
Rv1933c|M.tuberculosis_H37Rv --------------------------------------------------
MAV_2570|M.avium_104 FGLLLARTGPDKHRDLSMFVVPMDIPGVTVRPLTQMDGESKFNEVFFDGA
MAB_3123|M.abscessus_ATCC_1997 --------------------------------------------------
MLBr_00737|M.leprae_Br4923 --------------------------------------------------
TH_0804|M.thermoresistible__bu --------------------------------------------------
MSMEG_6585|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_0345|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_0393|M.vanbaalenii_PYR-1 --------------------------------------------------
MMAR_1954|M.marinum_M --------------------------------------------------
MUL_2176|M.ulcerans_Agy99 --------------------------------------------------
Mb1968c|M.bovis_AF2122/97 --------------------------------------------------
Rv1933c|M.tuberculosis_H37Rv --------------------------------------------------
MAV_2570|M.avium_104 ELDEDALIGEVGQGWTVAMVTLGRERLTLGSQAVSMFRLHERMVDAARDH
MAB_3123|M.abscessus_ATCC_1997 --------------------------------------------------
MLBr_00737|M.leprae_Br4923 --------------------------------------------------
TH_0804|M.thermoresistible__bu --------------------------------------------------
MSMEG_6585|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_0345|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_0393|M.vanbaalenii_PYR-1 --------------------------------------------------
MMAR_1954|M.marinum_M --------------------------------------------------
MUL_2176|M.ulcerans_Agy99 --------------------------------------------------
Mb1968c|M.bovis_AF2122/97 --------------------------------------------------
Rv1933c|M.tuberculosis_H37Rv --------------------------------------------------
MAV_2570|M.avium_104 DLLDPVLSRSMTRLWARMWLLRFTWQRAIDSGDLTSPAFSVLKLMTSETD
MAB_3123|M.abscessus_ATCC_1997 --------------------------------------------------
MLBr_00737|M.leprae_Br4923 --------------------------------------------------
TH_0804|M.thermoresistible__bu --------------------------------------------------
MSMEG_6585|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_0345|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_0393|M.vanbaalenii_PYR-1 --------------------------------------------------
MMAR_1954|M.marinum_M --------------------------------------------------
MUL_2176|M.ulcerans_Agy99 --------------------------------------------------
Mb1968c|M.bovis_AF2122/97 --------------------------------------------------
Rv1933c|M.tuberculosis_H37Rv --------------------------------------------------
MAV_2570|M.avium_104 QDLGDMATEVLGTDACTDPEEDGLVHHMLIGRAQTILGGTSEIQRNILGE
MAB_3123|M.abscessus_ATCC_1997 --------------------------------------------------
MLBr_00737|M.leprae_Br4923 --------------------------------------------------
TH_0804|M.thermoresistible__bu ----------
MSMEG_6585|M.smegmatis_MC2_155 ----------
Mflv_0345|M.gilvum_PYR-GCK ----------
Mvan_0393|M.vanbaalenii_PYR-1 ----------
MMAR_1954|M.marinum_M ----------
MUL_2176|M.ulcerans_Agy99 ----------
Mb1968c|M.bovis_AF2122/97 ----------
Rv1933c|M.tuberculosis_H37Rv ----------
MAV_2570|M.avium_104 RVLGLPKEPR
MAB_3123|M.abscessus_ATCC_1997 ----------
MLBr_00737|M.leprae_Br4923 ----------