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aa seq not available
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. thermoresistible (build 8) | TH_4005 | - | - | 100% (533) | NADH-ubiquinone oxidoreductase/multisubunit na+/h+ antiporter, d |
| M. thermoresistible (build 8) | TH_1092 | nuoN | 4e-40 | 27.75% (519) | PROBABLE NADH DEHYDROGENASE I (CHAIN N) NUON |
| M. thermoresistible (build 8) | TH_1091 | nuoM | 3e-37 | 26.11% (475) | PROBABLE NADH DEHYDROGENASE I (CHAIN M) NUOK |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0086 | - | 5e-38 | 28.99% (445) | oxidoreductase |
| M. gilvum PYR-GCK | Mflv_0164 | - | 0.0 | 81.65% (534) | putative monovalent cation/H+ antiporter subunit D |
| M. tuberculosis H37Rv | Rv0083 | - | 5e-38 | 28.99% (445) | oxidoreductase |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_0634c | - | 0.0 | 77.07% (532) | putative monovalent cation/H+ antiporter subunit D |
| M. marinum M | MMAR_1471 | nuoM | 4e-36 | 28.07% (374) | NADH dehydrogenase I (chain M) NuoM (NADH- ubiquinone |
| M. avium 104 | MAV_4045 | - | 9e-40 | 31.55% (336) | NADH dehydrogenase subunit M |
| M. smegmatis MC2 155 | MSMEG_0846 | - | 0.0 | 82.58% (528) | putative monovalent cation/H+ antiporter subunit D |
| M. ulcerans Agy99 | MUL_2471 | nuoM | 1e-36 | 29.07% (375) | NADH dehydrogenase subunit M |
| M. vanbaalenii PYR-1 | Mvan_0742 | - | 0.0 | 82.04% (529) | putative monovalent cation/H+ antiporter subunit D |
CLUSTAL 2.0.9 multiple sequence alignment
Mb0086|M.bovis_AF2122/97 ---------------MTAAPTAGGVVTSG-----------------VGVA
Rv0083|M.tuberculosis_H37Rv ---------------MTAAPTAGGVVTSG-----------------VGVA
TH_4005|M.thermoresistible__bu ---MNLAATLTPLPVLIPTLSAAATLIAGRRVRLQRMIALLSLTAMVAVC
MSMEG_0846|M.smegmatis_MC2_155 ----MMVQTLIPLPVLIPTLAAAATLIAGRRPHLQRAIAQIALTAVVAVC
Mflv_0164|M.gilvum_PYR-GCK MIGAHLASVLTPLPVLIPMLGAAATLIAGRRPRLQRAIVVSGLSAVVAVS
Mvan_0742|M.vanbaalenii_PYR-1 MIGAQFASVLTPLPVLVPMLAAAATLIAGRRPRLQRSIVVLALSTVVAVS
MAB_0634c|M.abscessus_ATCC_199 ---MSTMSVLTPLPVLVPTTAAALTLIAGRRPRLQLLITVTALTTVLGVC
MMAR_1471|M.marinum_M -----MNSHVPWLTLLWLVPLAASVLIILLPPGLRQLAKWTGLIASVVTL
MUL_2471|M.ulcerans_Agy99 ----MVNSHVPWLTLLWLVPLAASVLTILLPPGLRQLAKWTGLIASVVTL
MAV_4045|M.avium_104 -----MN-QLPWLSILWLVPLAGSVLIILMPPGLRQLAKWTGLVFGVLTL
: *. .: : .
Mb0086|M.bovis_AF2122/97 GVGVGLLGMFGPVRVVHVGWLLPLS-----GVHIELDRLGGFFMALTGAV
Rv0083|M.tuberculosis_H37Rv GVGVGLLGMFGPVRVVHVGWLLPLS-----GVHIELDRLGGFFMALTGAV
TH_4005|M.thermoresistible__bu AVLLYLTDRDGTVVVHVGGWGEIVGGLGPLGITLVVDRLAAMMLVVSSIV
MSMEG_0846|M.smegmatis_MC2_155 GVLLYLSDRDGTLVLHVGGWDQAIPGMGPLGITLVVDRLSALMLVVSSIV
Mflv_0164|M.gilvum_PYR-GCK AALLYLADRDGTIALQVGGWGPTEDGLGPLGVTLVVDRLSALMLVVSSIV
Mvan_0742|M.vanbaalenii_PYR-1 AALLYLADRDGTFALQVGGWGSTEAGMGPLGVTLVVDRLSALMLVVSSIV
MAB_0634c|M.abscessus_ATCC_199 TALLYLTDRDGTFALAVGGWGPTEEKLGPLGITLVVDRLSALMLVVSAIV
MMAR_1471|M.marinum_M AVSVVVATGFKPSGEHYQ-FVENRSWIPAFGASYTLG-VDGIAVVLVLLT
MUL_2471|M.ulcerans_Agy99 AMSVVVATGFKPSGEHYQ-FVENRSWIPAFGASYTLG-VDGIAVVLVLLT
MAV_4045|M.avium_104 AVAIVVTAGFKTGGAPYQ-FVEKHQWIPAFGAGYTLG-VDGIAVVLVLLT
: : . : * :. : .: :.: .
Mb0086|M.bovis_AF2122/97 AAPVGCYLIGYVRREHLGRVPMAVVP----LFVAAMLLVPAAGSVTTFLL
Rv0083|M.tuberculosis_H37Rv AAPVGCYLIGYVRREHLGRVPMAVVP----LFVAAMLLVPAAGSVTTFLL
TH_4005|M.thermoresistible__bu LLAVVQYAIGQGVRDGDERQPVSIFIPTYLVLSAGVCMAFVAGDLFNLFV
MSMEG_0846|M.smegmatis_MC2_155 LLAVVVYAIGQGIRDGDERQPVSIFMPTYLVLSAGVYTAFLAGDLFNLFV
Mflv_0164|M.gilvum_PYR-GCK LLAVVFYAIGQGIRDGDERQPVSIFLPTYLVLSAGVFMAFLAGDLFNLFV
Mvan_0742|M.vanbaalenii_PYR-1 LLAVVFYAIGQGIRDGDERQPVSIFLPTYLVLSAGVFMAFLAGDLFNLFV
MAB_0634c|M.abscessus_ATCC_199 LLAVVLYAAAQGIRDGDERQPVSIFMPTYLALSAGVCNAFLAGDLFNLYV
MMAR_1471|M.marinum_M TVLIPLLQIAGWNDGGERTRGVHAYVALTLAIESMVLISVVALDVLLFYV
MUL_2471|M.ulcerans_Agy99 TVLIPLLQIAGWNDGGERTRGVHAYVALTLAIESMVLISVVALDVLLFYV
MAV_4045|M.avium_104 AVLIPVLQVAGWNDGGDRQRGVHAYVALTLAIESMVLVSVIALDVLLFYV
: . : : : : * .: : :
Mb0086|M.bovis_AF2122/97 AWELMAIASLILVLSEHARPQVRSAGLWYAVMTQLGFIAILVGLVVLAAA
Rv0083|M.tuberculosis_H37Rv AWELMAIASLILVLSEHARPQVRSAGLWYAVMTQLGFIAILVGLVVLAAA
TH_4005|M.thermoresistible__bu GFEVLLTASFVLLTIGASEERVR-AGTYYVMVSMVSSLIFLAGIGLVYAA
MSMEG_0846|M.smegmatis_MC2_155 GFEVLLAASFVLLTIGASADRVR-AGISYVLVSMVSSMIFLIGIALVYAS
Mflv_0164|M.gilvum_PYR-GCK GFEVLLTASFVLLTIGASKERVR-AGISYVMVSMVSSLVFLFGIALVYAT
Mvan_0742|M.vanbaalenii_PYR-1 GFEVLLTASFVLLTIGASKERVR-AGISYVMVSMVSSLVFLFGIALVYAT
MAB_0634c|M.abscessus_ATCC_199 GFEVLLAASFVLLTIGASADRVR-AGISYVMVSMMSSVVFLLGIAFVYAA
MMAR_1471|M.marinum_M FFEAMLIPMYFLIGGFGQGRARSGAAVKFLLYNLFGGLIMLAAVIGLYVV
MUL_2471|M.ulcerans_Agy99 FFEAMLIPMYFLIGGFGQGRARSGAAVKFLLYNLFGGLIMLAAVIGLYVV
MAV_4045|M.avium_104 FFEAMLIPMYFLIGGFGAGSGRSRAAVKFLLYNLFGGLIMLAAVIGLYVV
:* : . .*: *. : : . .. : :* .: : .
Mb0086|M.bovis_AF2122/97 GGSDR---------FAGLGA----VCDGVRVAVFMLTLVGFGSKAGLVPL
Rv0083|M.tuberculosis_H37Rv GGSDR---------FAGLGA----VCDGVRAAVFMLTLVGFGSKAGLVPL
TH_4005|M.thermoresistible__bu TGTLN---------MAELAVRLDDIAPGTRTALFAVLLIAFGIKAAVFPL
MSMEG_0846|M.smegmatis_MC2_155 TGTLN---------LAELGVRLTDLPPGTRTAIFAVLLVAFGIKAAVFPL
Mflv_0164|M.gilvum_PYR-GCK TGTLN---------LAEIAVRLDDVPEGTRMALFAVLLVAFGIKAAVFPL
Mvan_0742|M.vanbaalenii_PYR-1 TGTLN---------LAEIAVRLDDVPEGTRMALFAVLLVAFGIKAAVFPL
MAB_0634c|M.abscessus_ATCC_199 TGTLN---------MAEIALRADGIPSGTRMAIFAVLLVGFAIKAAVFPL
MMAR_1471|M.marinum_M TAQNGSGTFDFRDIVAGVQGGHYGEHPAVFKALFLGFMFAFAIKAPLWPF
MUL_2471|M.ulcerans_Agy99 TAQNGSGTFDFRDIVAGVQGGHYGEHPAVFKALFLGFMFAFAIKAPLWPF
MAV_4045|M.avium_104 TSQHGAGTFDFRDIVAGVASGRYGADPAVSKALFLGFMFAFAIKAPLWPF
. .* : .. *:* :..*. ** : *:
Mb0086|M.bovis_AF2122/97 HAWLPRAHPEAPSPVSALMSAAMVNLGIYGIVRFDLQLLGPGPRWWGLAL
Rv0083|M.tuberculosis_H37Rv HAWLPRAHPEAPSPVSALMSAAMVNLGIYGIVRFDLQLLGPGPRWWGLAL
TH_4005|M.thermoresistible__bu SSWLPDSYPTAPAPVTAVFAGLLTKVGVYAIIRTHSLLFPGAG--LDPLL
MSMEG_0846|M.smegmatis_MC2_155 SAWLPDSYPTAPAPVTAVFAGLLTKVGVYAIIRAHSLLFPDGG--LDSVL
Mflv_0164|M.gilvum_PYR-GCK SAWLPDSYPTAPAPVTAVFAGLLTKVGVYAIIRAHSLLFPGGG--MDRIL
Mvan_0742|M.vanbaalenii_PYR-1 SAWLPDSYPTAPAPVTAVFAGLLTKVGVYAIIRAHSLLFPGGG--MDRVL
MAB_0634c|M.abscessus_ATCC_199 STWLPDSYPTAPAPVTAVFAGLLTKVGVYAIIRAHSLLFPGGG--LNTVL
MMAR_1471|M.marinum_M HRWLPDAAVESTPATAVLMMAVMDKVGTFGMLRYCLQLFPDASTYFRPLI
MUL_2471|M.ulcerans_Agy99 HRWLPDAAVESTPATAVLMMAVMDKVGTFGMLRYCLQLFPDASTYFRPLI
MAV_4045|M.avium_104 HRWLPDAAVEATPATAVLMMAVMDKVGTFGMLRYCLQLFPDAATYFRPLI
*** : :....:.:: . : ::* :.::* *: . :
Mb0086|M.bovis_AF2122/97 LAVGGTSALYGVLQASVAADLKRLLAYSTTENMGLITLALGAATLFADTG
Rv0083|M.tuberculosis_H37Rv LAVGGTSALYGVLQASVAADLKRLLAYSTTENMGLITLALGAATLFADTG
TH_4005|M.thermoresistible__bu LIAALATMLIGILGAIAQSDIKRLLSFTLVSHIGYMVFGIALS-------
MSMEG_0846|M.smegmatis_MC2_155 LVAGLLTMVIGILGAIAQSDIKRLLSFTLVSHIGYMVFGIALG-------
Mflv_0164|M.gilvum_PYR-GCK LVAGLLTMVIGIFGAIAQSDIKRLLSFTLVSHIGYMVFGIALS-------
Mvan_0742|M.vanbaalenii_PYR-1 LVAGLLTMIIGIFGAIAQSDIKRLLSFTLVSHIGYMVFGIALS-------
MAB_0634c|M.abscessus_ATCC_199 LVAALLTMIVGILGAIAQSDIKRLLSFTLVSHIGYMIFGIALS-------
MMAR_1471|M.marinum_M VTLAIIGVIYGAVVAIGQTDIMRLIAYTSISHFGFIIAGIFVM-------
MUL_2471|M.ulcerans_Agy99 VTLAIIGVIYGAVVAIGQTDIMRLIAYTSISHFGFIIAGIFVM-------
MAV_4045|M.avium_104 VVLAVIGVIYGAIVAIGQADVMRLIAYTSISHFGFIILGIFVM-------
: . : * . * :*: **:::: .::* : .:
Mb0086|M.bovis_AF2122/97 AYGPASIAAAAAMLHMIAHAAFKSLAFMAAGSVLAATG-LRDLDLLGGLA
Rv0083|M.tuberculosis_H37Rv AYGPASIAAAAAMLHMIAHAAFKSLAFMAAGSVLAATG-LRDLDLLGGLA
TH_4005|M.thermoresistible__bu ----TQLGMSGAIYYVAHHIVVQTTLFLVVGLIERQAG-ASTLQRLGGLA
MSMEG_0846|M.smegmatis_MC2_155 ----NELGMAGAIYYVAHHIVVQTTLFLVVGLIERQAG-ASTLQRLGGLA
Mflv_0164|M.gilvum_PYR-GCK ----TQLGMAGAIYYVAHHILVQTTLFLVVGLIERQAG-ASTLERLGGLA
Mvan_0742|M.vanbaalenii_PYR-1 ----THLGMSGAIYYVAHHILVQTTLFLVVGLIERQAG-ASTLERLGGLA
MAB_0634c|M.abscessus_ATCC_199 ----NELGMSGAIYYVAHHIIVQTTLFLVVGLIERQAG-ASSLNRLGGLA
MMAR_1471|M.marinum_M ----TTQGQSGSTLYMLNHGLSTAAVFLIAGFLISRHG-SRAIADYGGVQ
MUL_2471|M.ulcerans_Agy99 ----TTQGQSGSTLYMLNHGLSTAAVFLIAGFLISRHG-SRAIADYGGVQ
MAV_4045|M.avium_104 ----TSQGQSGSTLYMLNHGLSTAAVFLIAGFLISRHGGSRAIADYGGVQ
. :.: :: * : *: .* : * : **:
Mb0086|M.bovis_AF2122/97 RRMPATTVFFGVAALGACGLPLGAGFVSEWLLVQSLIHAAPGHDPIVALT
Rv0083|M.tuberculosis_H37Rv RRMPATTVFFGVAALGACGLPLGAGFVSEWLLVQSLIHAAPGHDPIVALT
TH_4005|M.thermoresistible__bu AASPLLAFVFVVPALNLGGIPPFSGFIGKVALMEAGAADGS------VLA
MSMEG_0846|M.smegmatis_MC2_155 AASPVLAFVWVVPALNLGGIPPFSGFIGKIALMEAGAANGS------ALA
Mflv_0164|M.gilvum_PYR-GCK AASPLLAFVFVVPALNLGGIPPFSGFIGKVALLEAGAESGS------VLA
Mvan_0742|M.vanbaalenii_PYR-1 AASPLLAFVFVVPALNLGGIPPFSGFIGKVALLEAGAQSGS------VLA
MAB_0634c|M.abscessus_ATCC_199 AASPLLAFVFVVPALNLGGIPPFSGFIGKVALLEAGSLQGS------VLA
MMAR_1471|M.marinum_M KVAPVLAGTFLVSAMATLSLPGLAPFISEFLVLLGTFNRYW-------LA
MUL_2471|M.ulcerans_Agy99 KVAPVLAGTFLVSAMATLSLPGLAPFISEFLVLLGTFNRYW-------LA
MAV_4045|M.avium_104 KVAPVLAGTFLVSAMATLSLPGLAPFVSEFLVLLGTFNRYW-------LA
* : : *.*: .:* : *:.: :: . *:
Mb0086|M.bovis_AF2122/97 TPLAVGVVALATGLSVAAMTKAFGIGFLARPRSTQAEAAREAPASMRAGM
Rv0083|M.tuberculosis_H37Rv TPLAVGVVALATGLSVAAMTKAFGIGFLARPRSTQAEAAREAPASMRAGM
TH_4005|M.thermoresistible__bu WTLVGGSVVTSL-LTLYVVARVWTKAFWR--------SRADAPE----GH
MSMEG_0846|M.smegmatis_MC2_155 WTLVAGGVVTSL-LTLYVVARVWTKAFWR--------TRADAPE----GH
Mflv_0164|M.gilvum_PYR-GCK WILVAGSVITSL-LTLYVVARVWTKAFWR--------ARKDAPE----GH
Mvan_0742|M.vanbaalenii_PYR-1 WALVAGSVATSL-LTLYVVARVWTKAFWR--------SRKDAPE----GH
MAB_0634c|M.abscessus_ATCC_199 WALVAGGTITSL-LTLYAVARVWTKAFWR--------PRSDAPE----GD
MMAR_1471|M.marinum_M AAFGVTALVLSAIYMLWLYQRVMTGPLAK---------GNERIG------
MUL_2471|M.ulcerans_Agy99 AALGVTALVLSAIYMLWLYQRVMTGPLAK---------GNERIG------
MAV_4045|M.avium_104 AAFGVTALVLSAVYMLWLYQRMMTGPVAG---------GNEKIG------
: : : : . :
Mb0086|M.bovis_AF2122/97 AIAAGACLVLAVAPLLVAPMVRRAAATLPAAQAVKFTGLGAVVRLPAMSG
Rv0083|M.tuberculosis_H37Rv AIAAGACLVLAVAPLLVAPMVRRAAATLPAAQAVKFTGLGAVVRLPAMSG
TH_4005|M.thermoresistible__bu LSAAAPAVLLD------------------DIEDIEFAERRHVGRMPVSML
MSMEG_0846|M.smegmatis_MC2_155 LSQAAPAVLLD------------------DGEDIEYADREGVGRMPIGML
Mflv_0164|M.gilvum_PYR-GCK LSGPAPTALLDNT---------------DETMDIEHSDRDDVGRMPVGML
Mvan_0742|M.vanbaalenii_PYR-1 LSGPAPAALLDNT---------------DETMDIELADRDDVGRMPVGML
MAB_0634c|M.abscessus_ATCC_199 LAAAAPTALLD------------------DAEDVAFVDRADVGRIPAGML
MMAR_1471|M.marinum_M ----------------------------------DLVPREMIVVAPLIAM
MUL_2471|M.ulcerans_Agy99 ----------------------------------DLVPREMIVVAPLIAM
MAV_4045|M.avium_104 ----------------------------------DLRARELVVVAPLIAL
: *
Mb0086|M.bovis_AF2122/97 SIAPGVIAAAVLAAALAVAVLARWRFRRRPAPARLPLWACGAADLTVRMQ
Rv0083|M.tuberculosis_H37Rv SIAPGVIAAAVLAAALAVAVLARWRFRRRPAPARLPLWACGAADLTVRMQ
TH_4005|M.thermoresistible__bu VPTGGLILVGLALTIFAGPIVA---YSER-----------AAEQVLDRGR
MSMEG_0846|M.smegmatis_MC2_155 IPTAALIVVGLVLTVAAGPIFA---FSER-----------AAAEVIDRGQ
Mflv_0164|M.gilvum_PYR-GCK APTGALIVVGLALTVLAGPIIA---YSDR-----------AAAEVLDRSQ
Mvan_0742|M.vanbaalenii_PYR-1 APTGALIVVGLLLTILAGPIFG---YSDR-----------AAGEVIDRGQ
MAB_0634c|M.abscessus_ATCC_199 APTLGLIAVGVALTIFAGPIIA---ISDR-----------AAAEVRDRTV
MMAR_1471|M.marinum_M LLILGVYPKPVLDVINPAVEHTMSTIGQHD----------PAPKVPHPVS
MUL_2471|M.ulcerans_Agy99 LLILGVYPKPVLDVINPAVEHTMSTIGQHD----------PAPKVPHPVS
MAV_4045|M.avium_104 LLVLGIYPKPVLDIINPAVENTMTTIGQHD----------PAPSVP----
.: : . : * .:
Mb0086|M.bovis_AF2122/97 YTATSFAEPLQRVFGDVLRPDTDIEVTHTAESRYMAERITYRTAVADAIE
Rv0083|M.tuberculosis_H37Rv YTATSFAEPLQRVFGDVLRPDTDIEVTHTAESRYMAERITYRTAVADAIE
TH_4005|M.thermoresistible__bu YIGAVIGEAP----------------------------------------
MSMEG_0846|M.smegmatis_MC2_155 YITAVLGETR----------------------------------------
Mflv_0164|M.gilvum_PYR-GCK YIGAVLGGQP----------------------------------------
Mvan_0742|M.vanbaalenii_PYR-1 YIGAVLGGTR----------------------------------------
MAB_0634c|M.abscessus_ATCC_199 YISAVLGGAPR---------------------------------------
MMAR_1471|M.marinum_M GVSAPRTAEGPHE-------------------------------------
MUL_2471|M.ulcerans_Agy99 GVSAPRTAEGPHE-------------------------------------
MAV_4045|M.avium_104 -MGTPRTAEGRR--------------------------------------
:
Mb0086|M.bovis_AF2122/97 QRLYTPVVGAVAAMAELLRRAHTGSVHRYLAYGALGVLIVLVVARCT
Rv0083|M.tuberculosis_H37Rv QRLYTPVVGAVAAMAELLRRAHTGSVHRYLAYGALGVLIVLVVAR--
TH_4005|M.thermoresistible__bu -----------------------------------------------
MSMEG_0846|M.smegmatis_MC2_155 -----------------------------------------------
Mflv_0164|M.gilvum_PYR-GCK -----------------------------------------------
Mvan_0742|M.vanbaalenii_PYR-1 -----------------------------------------------
MAB_0634c|M.abscessus_ATCC_199 -----------------------------------------------
MMAR_1471|M.marinum_M -----------------------------------------------
MUL_2471|M.ulcerans_Agy99 -----------------------------------------------
MAV_4045|M.avium_104 -----------------------------------------------