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M. tuberculosis H37Rv Rv0083 (-)

annotation: PROBABLE OXIDOREDUCTASE
coordinates: 90400 - 92322
length: 640

MTAAPTAGGVVTSGVGVAGVGVGLLGMFGPVRVVHVGWLLPLSGVHIELDRLGGFFMALTGAVAAPVGCY
LIGYVRREHLGRVPMAVVPLFVAAMLLVPAAGSVTTFLLAWELMAIASLILVLSEHARPQVRSAGLWYAV
MTQLGFIAILVGLVVLAAAGGSDRFAGLGAVCDGVRAAVFMLTLVGFGSKAGLVPLHAWLPRAHPEAPSP
VSALMSAAMVNLGIYGIVRFDLQLLGPGPRWWGLALLAVGGTSALYGVLQASVAADLKRLLAYSTTENMG
LITLALGAATLFADTGAYGPASIAAAAAMLHMIAHAAFKSLAFMAAGSVLAATGLRDLDLLGGLARRMPA
TTVFFGVAALGACGLPLGAGFVSEWLLVQSLIHAAPGHDPIVALTTPLAVGVVALATGLSVAAMTKAFGI
GFLARPRSTQAEAAREAPASMRAGMAIAAGACLVLAVAPLLVAPMVRRAAATLPAAQAVKFTGLGAVVRL
PAMSGSIAPGVIAAAVLAAALAVAVLARWRFRRRPAPARLPLWACGAADLTVRMQYTATSFAEPLQRVFG
DVLRPDTDIEVTHTAESRYMAERITYRTAVADAIEQRLYTPVVGAVAAMAELLRRAHTGSVHRYLAYGAL
GVLIVLVVAR
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. tuberculosis H37RvRv0083--100% (640)PROBABLE OXIDOREDUCTASE
M. tuberculosis H37RvRv3156nuoL2e-4328.81% (545) NADH dehydrogenase subunit L
M. tuberculosis H37RvRv0086hycQ7e-3830.28% (436) hydrogenase HycQ

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb0086-0.099.84% (640) oxidoreductase
M. gilvum PYR-GCKMflv_0162-8e-3931.32% (530) putative monovalent cation/H+ antiporter subunit A
M. leprae Br4923-----
M. abscessus ATCC 19977MAB_2145-2e-4027.86% (639) NADH dehydrogenase subunit L
M. marinum MMMAR_1655-0.067.41% (632) oxidoreductase
M. avium 104MAV_5113-0.076.86% (618) NADH dehydrogenase subunit n
M. smegmatis MC2 155MSMEG_2052nuoL2e-4226.96% (649) NADH dehydrogenase subunit L
M. thermoresistible (build 8)TH_1090nuoL5e-4329.60% (500) PROBABLE NADH DEHYDROGENASE I (CHAIN L) NUOL
M. ulcerans Agy99MUL_1892-0.066.98% (633) oxidoreductase
M. vanbaalenii PYR-1Mvan_1874-3e-3826.84% (611) NADH dehydrogenase subunit L

CLUSTAL 2.0.9 multiple sequence alignment


MSMEG_2052|M.smegmatis_MC2_155      --MITDWLPVWLLIALPAAGATILLLAGRRSDRWGHLLGCAMSLAAFAVG
Mvan_1874|M.vanbaalenii_PYR-1       ---MT--APVWLLIALPLAGAAILLLSGRRSDRWGHLLGTAAAIASFVCA
TH_1090|M.thermoresistible__bu      ---MT--IPLWLLIALPAVGATVLLLAGRRADPWGHLLGCAAALASFGVA
MAB_2145|M.abscessus_ATCC_1997      MT--------WLMPALPLAGAAVLLLVGRRGDARGHLVGCAASLGSFLVA
Rv0083|M.tuberculosis_H37Rv         ------------------------------MTAAPTAGGVVTSGVGVAGV
Mb0086|M.bovis_AF2122/97            ------------------------------MTAAPTAGGVVTSGVGVAGV
MAV_5113|M.avium_104                --------------------------------------------------
MMAR_1655|M.marinum_M               ------------MTATLSDAPPEHQVALSGNGFGAVLSGATTAGIGACGT
MUL_1892|M.ulcerans_Agy99           -----------------------------------MLSGATTAGIGACGT
Mflv_0162|M.gilvum_PYR-GCK          ------------MLAILAAHAAAALLAPLLVYRWGRLAFYPLALVPLGSL
                                                                                      

MSMEG_2052|M.smegmatis_MC2_155      TVLFAGMLGRSGEERAVHEALFSWVPVGGLQVDFGLQLDQLSVCFVLLIT
Mvan_1874|M.vanbaalenii_PYR-1       ALLFTDMLGRDGENRSVQESLFSWVPAGELRVDFGLQLDQLSMCFVLLIT
TH_1090|M.thermoresistible__bu      AVLFVDMLGRPGDQRGTVATLFSWVPVADLQIDFGLQLDQLSMCFALLIT
MAB_2145|M.abscessus_ATCC_1997      VVAFLGMLGRAGPDRVMHEVLFNWVPVGGLHIDFGLTLDQLSVCFALLIT
Rv0083|M.tuberculosis_H37Rv         GVGLLGMFG------PVRVVHVGWLLP---LSGVHIELDRLGGFFMALTG
Mb0086|M.bovis_AF2122/97            GVGLLGMFG------PVRVVHVGWLLP---LSGVHIELDRLGGFFMALTG
MAV_5113|M.avium_104                MCGIAAVFG------VRQTVHVGWLLP---LSGLQLDLDPVGGFFMALIG
MMAR_1655|M.marinum_M               ALGLTAVFG------VVRQVHIAWLVP---LIGVDFDIGRLGGFFIALTG
MUL_1892|M.ulcerans_Agy99           ALGLTAVFG------VVRQVHIAWLVP---LIGVDFDIGRLGGFVIALTG
Mflv_0162|M.gilvum_PYR-GCK          VWVVLNWPAKG----QSRNVDVPWVPG--LSMDITLRFDALAAIMSVLVL
                                       .    .            . *:       .. : :. :.  .  *  

MSMEG_2052|M.smegmatis_MC2_155      GVGSLIHIYSIGYMAEDP-----DRRRFFAYLNLFLAAMLLLVLADNYLG
Mvan_1874|M.vanbaalenii_PYR-1       GVGSLIHVYSIGYMAEDP-----GRRRFFGYLNLFLAAMLLLVLADNYLG
TH_1090|M.thermoresistible__bu      GVGSLIHIYSVGYMREDP-----ERRKFFAYLNLFLSAMLLLVLADNFFG
MAB_2145|M.abscessus_ATCC_1997      GVGSLIHVYSIGYMAHDP-----DRRRFFGYLNLFLAAMLLLVLADNFLG
Rv0083|M.tuberculosis_H37Rv         AVAAPVGCYLIGYVRREH-----LGRVPMAVVPLFVAAMLLVPAAGSVTT
Mb0086|M.bovis_AF2122/97            AVAAPVGCYLIGYVRREH-----LGRVPMAVVPLFVAAMLLVPAAGSVTT
MAV_5113|M.avium_104                GVAVPVGFYSIGYARREH-----LGRVSLAMLPLFVAAMMLVPAAGSVTT
MMAR_1655|M.marinum_M               AVAVVAGIYSIGYARREH-----LGAVALTMLPVFVTAMLLVPAAGSVST
MUL_1892|M.ulcerans_Agy99           AVTVVAGIYSIGYARREH-----LGAVALTMLPVFVTAMLLVPAAGSVST
Mflv_0162|M.gilvum_PYR-GCK          AIGALVLFYCADYFRHHDGRIEKRLPSFAAELVAFSGAMFGLVTSDNMLV
                                    .:      *  .*  ..              :  *  **: :  :..   

MSMEG_2052|M.smegmatis_MC2_155      LYAGWEGVGLASYLLIGFWSHKPSAATAAKKAFVVNRVGDMGLAIALMIM
Mvan_1874|M.vanbaalenii_PYR-1       LYMGWEGVGLASYLLIGFWSHKPSAATAAKKAFVVNRVGDVGLAVALMVM
TH_1090|M.thermoresistible__bu      LYVGWEGVGLASYLLIGFWAHKPSAATAAKKAFVVNRVGDMGLVIAMAVM
MAB_2145|M.abscessus_ATCC_1997      LYLGWEGVGLASYLLIGFWYQKPSAAAAAKKAFIVNRVGDMGLALAMMLM
Rv0083|M.tuberculosis_H37Rv         FLLAWELMAIASLILVLSEHARPQVRSAGLWYAVMTQLGFIAILVGLVVL
Mb0086|M.bovis_AF2122/97            FLLAWELMAIASLILVLSEHARPQVRSAGLWYAVMTQLGFIAILVGLVVL
MAV_5113|M.avium_104                FLLAWELMATASLVLVLAQHTRPEVRSAGLFYAVMTQLGFVAILIGLMVL
MMAR_1655|M.marinum_M               FLLAWELMAISSLVLVATDHRRAQVRSAAGYYAVMTQLGFATLLLGLMVL
MUL_1892|M.ulcerans_Agy99           FLLAWELMAISSLVLVATDHRRAQVRSAAGYYAVMTQLGFATLLLGLMVL
Mflv_0162|M.gilvum_PYR-GCK          LYVFWEITTVLSFLLVGHYAERATTRRAAMQALLVTTFGGLAMLVGIVVI
                                    :   **     * :*:     :. .  *.    ::. .*   : :.: ::

MSMEG_2052|M.smegmatis_MC2_155      FATIGSISFAGVFAAAPGLSEATLSAIGLLLLLGACGKSAQVPLQSWLG-
Mvan_1874|M.vanbaalenii_PYR-1       FAAVGAVGFTEVFDAAPQLGEGTLTVLGLMLLLAACGKSAQVPLQSWLG-
TH_1090|M.thermoresistible__bu      FAAAGSVSFSGVFGAAPQLGEGTLTAIGLLLLLAACGKSAQVPLQSWLG-
MAB_2145|M.abscessus_ATCC_1997      FSTFGSVGFAQVLGSASAAGESRNTAIGLALLLAACGKSAQVPLQSWLG-
Rv0083|M.tuberculosis_H37Rv         AAAGGSDRFAGLGAVC----DGVRAAVFMLTLVGFGSKAGLVPLHAWLPR
Mb0086|M.bovis_AF2122/97            AAAGGSDRFAGLGAVC----DGVRVAVFMLTLVGFGSKAGLVPLHAWLPR
MAV_5113|M.avium_104                SAAGGADRFADLTRVS----DGARTVVFVLTMAGFGSKAGLVPLHAWLPR
MMAR_1655|M.marinum_M               AAAAGTDRFADMAVPS----EGVRTFVFVATLLGFGSKAGLLPLHAWLPR
MUL_1892|M.ulcerans_Agy99           AAAAGTDRFADMAVPS----EGVRTFVFVATLLGFGSKAGLLPLHAWLPR
Mflv_0162|M.gilvum_PYR-GCK          GNIADTFLLSELIANPP--TGVAASVALVLILVGALSKSAIVPLHFWLP-
                                        .:  :: :                :  : .  .*:. :**: **  

MSMEG_2052|M.smegmatis_MC2_155      DAMEGPTPVSALIHAATMVTAGVYLIVRSG-PIFDLAP-TAQTGVVIVGA
Mvan_1874|M.vanbaalenii_PYR-1       DAMEGPTPVSALIHAATMVTAGVYLIVRSG-PVFDLAP-HAQTAVVVVGA
TH_1090|M.thermoresistible__bu      DAMEGPTPVSALIHAATMVTAGVYLIVRSG-PVFDLAP-GAQLAVVAVGA
MAB_2145|M.abscessus_ATCC_1997      DAMEGPTPVSALIHAATMVTAGVYLITRSG-PIFEHAP-YAQVAVVLVGA
Rv0083|M.tuberculosis_H37Rv         AHPEAPSPVSALMSAA-MVNLGIYGIVRFDLQLLGPGPRWWGLALLAVGG
Mb0086|M.bovis_AF2122/97            AHPEAPSPVSALMSAA-MVNLGIYGIVRFDLQLLGPGPRWWGLALLAVGG
MAV_5113|M.avium_104                AHPEAPSPVSALMSAA-MVNLGVYGIVRFDLQLLGPGPRWWAITLLVVGG
MMAR_1655|M.marinum_M               AHPESPSPVSALMSAA-MVNLGIYGLVRIDLQLLGPGPKWWGVTLLVIGA
MUL_1892|M.ulcerans_Agy99           AHPESPSPVSALMSAA-MVNLGIYGLVRIDLQLLGPGPKWWGVTLLVIGA
Mflv_0162|M.gilvum_PYR-GCK          GAMAAPTPVSAYLHAAAMVKAGVYLIARMTPGFADSPE--WRPTVVGLGL
                                        .*:**** : ** **. *:* :.*    .           :: :* 

MSMEG_2052|M.smegmatis_MC2_155      VTLLFGAIIGCAKDDIKKALAASTMSQIGYMVLAAGLG------------
Mvan_1874|M.vanbaalenii_PYR-1       VTLLFGAVIGCAKDDIKKALAASTMSQIGYMVLAAGLG------------
TH_1090|M.thermoresistible__bu      VTLLFGAIIGCAKDDIKKALAASTMSQIGYMVLAAGLG------------
MAB_2145|M.abscessus_ATCC_1997      VTLLFGAIIGCAKDDIKKALAASTMSQIGYMVLAAGLG------------
Rv0083|M.tuberculosis_H37Rv         TSALYGVLQASVAADLKRLLAYSTTENMGLITLALGAATLFADTGAYGPA
Mb0086|M.bovis_AF2122/97            TSALYGVLQASVAADLKRLLAYSTTENMGLITLALGAATLFADTGAYGPA
MAV_5113|M.avium_104                VSAVYGVLQASVATDLKRLLAYSTTENMGLITLALGAATLLADSGAHSAA
MMAR_1655|M.marinum_M               FSAMYGVLQASVATDLKRLLGYSTIENMGLVTLGLGAATLLSAAGAGPAA
MUL_1892|M.ulcerans_Agy99           FSAMYGVLQASVATDLKRLLGYSTIENMGLVTLGLGAATLLSAAGAGPAA
Mflv_0162|M.gilvum_PYR-GCK          LTMLLAGWRAIREYDLKLILAFGTVSQLGFITIMVGVG-----------G
                                     : : .   .    *:*  *. .* .::* :.:  * .            

MSMEG_2052|M.smegmatis_MC2_155      PAGYAFAIMHLLTHGFFKAGLFLGAGSVMHAMNDEVNMRRYGGLRKVLPV
Mvan_1874|M.vanbaalenii_PYR-1       PAGYAFAIMHLLTHGFFKAGLFLGAGSVMHAMDDEVDMRRYGGLRRALPV
TH_1090|M.thermoresistible__bu      PAGYAFAIMHLLTHGFFKAGLFLGAGSVMHAMNDEVDMRRYGGLRSVLPI
MAB_2145|M.abscessus_ATCC_1997      PAGYAVAIMHLLTHGFFKAGLFLGAGSVMHGMNEETDMRRYGGLRAVMPI
Rv0083|M.tuberculosis_H37Rv         SIAAAAAMLHMIAHAAFKSLAFMAAGSVLAAT-GLRDLDLLGGLARRMPA
Mb0086|M.bovis_AF2122/97            SIAAAAAMLHMIAHAAFKSLAFMAAGSVLAAT-GLRDLDLLGGLARRMPA
MAV_5113|M.avium_104                TIAMAAALLHLIGHAAFKSLGFLAAGSVLAAT-GLRDLDLLGGLARRMPA
MMAR_1655|M.marinum_M               VIAMTAALLHLIAHAAFKSLGFLAAGSVLVAT-QQRDLDMLGGLAHRMRC
MUL_1892|M.ulcerans_Agy99           VIAMTAALLHLIAHAAFKSLGFLAAGSVLVAT-QQRDLDMLGGLAHRMRC
Mflv_0162|M.gilvum_PYR-GCK          SEMMLAGLAMLCAHAMFKAALFMVVGIIDHAT-GTRDIRRLAWLGDRSKP
                                          .:  :  *. **:  *: .* :  .     ::   . *      

MSMEG_2052|M.smegmatis_MC2_155      TFATFGLGYLAIIGVPPLAGFFSKDGIIEAALG-----------------
Mvan_1874|M.vanbaalenii_PYR-1       TFVTFGLGYLAIIGIPPLAGFFSKDGIIEVALG-----------------
TH_1090|M.thermoresistible__bu      TFATFGLGYLAIIGVPPLAGFFSKDAIIEVALA-----------------
MAB_2145|M.abscessus_ATCC_1997      TFVTFGLGYLAIIGVPPFAGFYSKDKIIEVAFG-----------------
Rv0083|M.tuberculosis_H37Rv         TTVFFGVAALGACGLPLGAGFVSEWLLVQSLIH-----------------
Mb0086|M.bovis_AF2122/97            TTVFFGVAALGACGLPLGAGFVSEWLLVQSLIH-----------------
MAV_5113|M.avium_104                TTALFGVAALGASGLPLGAGFVSEWLLVQSLIH-----------------
MMAR_1655|M.marinum_M               TTTFFGIAALGASGLPLGAGFVSEWLLVQSLIH-----------------
MUL_1892|M.ulcerans_Agy99           TTTFFGIAALGASGLPLGAGFVSEWLLVQSLIH-----------------
Mflv_0162|M.gilvum_PYR-GCK          LLIIGCAAAASMAALPPFFGFIAKEADFETVLHSPYLGAASPFVLAGIVL
                                           .  .  .:*   ** ::   .:  :                  

MSMEG_2052|M.smegmatis_MC2_155      --------------------------------------------------
Mvan_1874|M.vanbaalenii_PYR-1       --------------------------------------------------
TH_1090|M.thermoresistible__bu      --------------------------------------------------
MAB_2145|M.abscessus_ATCC_1997      --------------------------------------------------
Rv0083|M.tuberculosis_H37Rv         --------------------------------------------------
Mb0086|M.bovis_AF2122/97            --------------------------------------------------
MAV_5113|M.avium_104                --------------------------------------------------
MMAR_1655|M.marinum_M               --------------------------------------------------
MUL_1892|M.ulcerans_Agy99           --------------------------------------------------
Mflv_0162|M.gilvum_PYR-GCK          GSVLTTVYSLRFVFGAFGRKGLPHPSTRVEEMHRPELGFLIPPAILAAAG
                                                                                      

MSMEG_2052|M.smegmatis_MC2_155      --------------------------------------------------
Mvan_1874|M.vanbaalenii_PYR-1       --------------------------------------------------
TH_1090|M.thermoresistible__bu      --------------------------------------------------
MAB_2145|M.abscessus_ATCC_1997      --------------------------------------------------
Rv0083|M.tuberculosis_H37Rv         --------------------------------------------------
Mb0086|M.bovis_AF2122/97            --------------------------------------------------
MAV_5113|M.avium_104                --------------------------------------------------
MMAR_1655|M.marinum_M               --------------------------------------------------
MUL_1892|M.ulcerans_Agy99           --------------------------------------------------
Mflv_0162|M.gilvum_PYR-GCK          LVFGLWPKPLDTVLSNYSDTVPDPQGYDGDYYLALWHGVNLPLILSALVL
                                                                                      

MSMEG_2052|M.smegmatis_MC2_155      -------------------------AGGARGVILGGAAILGAGITAFY--
Mvan_1874|M.vanbaalenii_PYR-1       -------------------------AGGAKGVILGGATILGAGITAFY--
TH_1090|M.thermoresistible__bu      -------------------------AGGVKGVVLGGAALLGAGITAFY--
MAB_2145|M.abscessus_ATCC_1997      -------------------------HGGAGGFLLGAAALSGAGITAFY--
Rv0083|M.tuberculosis_H37Rv         -------------------------AAPGHDPIVALTTPLAVGVVALATG
Mb0086|M.bovis_AF2122/97            -------------------------AAPGHDPIVALTTPLAVGVVALATG
MAV_5113|M.avium_104                -------------------------AAPQHNTVVALAAPLAVGAVALTTG
MMAR_1655|M.marinum_M               -------------------------ARPEHNTIVGLATPLGVGAVALTTG
MUL_1892|M.ulcerans_Agy99           -------------------------ARPEHNTIVGLATPLGVGAVALTTG
Mflv_0162|M.gilvum_PYR-GCK          LAGVAVCVGRGRLRRARLPYVPLGNADRTYDAVIRGADILSVRLTALTQR
                                                                  . ::  :   ..  .*:   

MSMEG_2052|M.smegmatis_MC2_155      -----MTRVMLMTFFGEKRWAANSHPHEAPAVMTWP----------MILL
Mvan_1874|M.vanbaalenii_PYR-1       -----MTRVMLMTFFGEKRWAEDNHPHESPAVMTWP----------MILL
TH_1090|M.thermoresistible__bu      -----MTRVMLLTFFGERRWEPTAQPHESPPVMTVP----------MILL
MAB_2145|M.abscessus_ATCC_1997      -----MTRVMLLTFFGKRRWHRDVHPHESPSVMTWP----------MLVL
Rv0083|M.tuberculosis_H37Rv         LSVAAMTKAFGIGFLARPRSTQAEAAREAPASMRAG----------MAIA
Mb0086|M.bovis_AF2122/97            LSVAAMTKAFGIGFLARPRSTQAEAAREAPASMRAG----------MAIA
MAV_5113|M.avium_104                LGVAAMVKAFGIGFLARPRSQPAADAREVPAVMVAG----------MALA
MMAR_1655|M.marinum_M               LGVAAMVKAFGTGFLARPRSGSAERAREAPATMLVG----------MAVA
MUL_1892|M.ulcerans_Agy99           LGVAAMVKAFGTGFLARPRSGSAERAREPPATMLVG----------MAVA
Mflv_0162|M.gilvum_PYR-GCK          GSLPQTQSFILITLVLLPLGVLAFGARDRPEFALWDSPPQVIVGLLMVAA
                                             :   :.          .:: *                *   

MSMEG_2052|M.smegmatis_MC2_155      AVGSVVSG------------------------------------------
Mvan_1874|M.vanbaalenii_PYR-1       AIGSVTAG------------------------------------------
TH_1090|M.thermoresistible__bu      AVGSVASG------------------------------------------
MAB_2145|M.abscessus_ATCC_1997      AVGSVAAG------------------------------------------
Rv0083|M.tuberculosis_H37Rv         AGACLVLA------------------------------------------
Mb0086|M.bovis_AF2122/97            AGACLVLA------------------------------------------
MAV_5113|M.avium_104                ATGCVVVA------------------------------------------
MMAR_1655|M.marinum_M               ALGCVVIA------------------------------------------
MUL_1892|M.ulcerans_Agy99           ALGCVVIA------------------------------------------
Mflv_0162|M.gilvum_PYR-GCK          AIAAVVMRNRLAAVLMVGVTGYGCGAIFAFHGAPDLALTQFLVETLTLVA
                                    * ..:.                                            

MSMEG_2052|M.smegmatis_MC2_155      --------------------------GALAIGGTLSH-------------
Mvan_1874|M.vanbaalenii_PYR-1       --------------------------GALAIGGTLEH-------------
TH_1090|M.thermoresistible__bu      --------------------------AVLAVGGTLQH-------------
MAB_2145|M.abscessus_ATCC_1997      --------------------------FLLSLGGALQN-------------
Rv0083|M.tuberculosis_H37Rv         --------------------------VAPLLVAPMVRRAAATLPAAQAVK
Mb0086|M.bovis_AF2122/97            --------------------------VAPLLVAPMVRRAAATLPAAQAVK
MAV_5113|M.avium_104                --------------------------VAPLVVGSMLGRVLTELPASRAVA
MMAR_1655|M.marinum_M               --------------------------IAPAVVTGPLQSVLDTLPASRNAD
MUL_1892|M.ulcerans_Agy99           --------------------------IAPAVVTGPLQSLLDTLPASRNAD
Mflv_0162|M.gilvum_PYR-GCK          FVLVLRTLPAETSREENTRYRLPRAALALAVGAAVTTLAAYAMAARTGRP
                                                                  :                   

MSMEG_2052|M.smegmatis_MC2_155      --WLEPVVGTHEAHHA---------VPVWVVTAIVLAVVAVGIAVAYRMY
Mvan_1874|M.vanbaalenii_PYR-1       --WLEPVVGAHEIHHV---------LPVWVVTVIVLSVVAVGIVVAYRMY
TH_1090|M.thermoresistible__bu      --WLEPVVGVHEAHHV---------VPVWVVTATVLATVAVGIVVAYRMY
MAB_2145|M.abscessus_ATCC_1997      --WLAPVVGMHHGELP---------VPGWVISAITVAVVLCGAGIAYRIY
Rv0083|M.tuberculosis_H37Rv         FTGLGAVVRLPAMSGS---------IAPGVIAAAVLAAALAVAVLARWRF
Mb0086|M.bovis_AF2122/97            FTGLGAVVRLPAMSGS---------IAPGVIAAAVLAAALAVAVLARWRF
MAV_5113|M.avium_104                FTDFGAVLRLPGLHGS---------IAPGAIAAALAAAVLAAVGLACWRS
MMAR_1655|M.marinum_M               LTDLGTVLRLPGMDGS---------ISPALLAAALVAALLVVLVLARWGS
MUL_1892|M.ulcerans_Agy99           LTDLGTVLRLPGMDGS---------IAPALLAAALVAALLVVLVLARWGS
Mflv_0162|M.gilvum_PYR-GCK          IADLLPEAAYVLGHGSNTVNVLLVDIRAWDTMGEISVLLVAATGVASMVF
                                       : .                   :                  :*    

MSMEG_2052|M.smegmatis_MC2_155      ARQAVPEEVP--EGSALTVAAR-RDLYGDAFNEAVFMRGGQTLTA-----
Mvan_1874|M.vanbaalenii_PYR-1       GFRAVPEQVP--AGSALTVAAR-RDLYGDTFNETVLMRPGMSLTR-----
TH_1090|M.thermoresistible__bu      AMRPVPVEVP--EGSALTVAAR-RDLYGDAFNEAVFMRTGQGLTR-----
MAB_2145|M.abscessus_ATCC_1997      R-ADVPETAP--QGSTLTVAAR-RDLYGDAFNEAVFMRPGQRLTR-----
Rv0083|M.tuberculosis_H37Rv         RRRPAPARLPLWACGAADLTVR-MQYTATSFAEPLQRVFGDVLRPDTDIE
Mb0086|M.bovis_AF2122/97            RRRPAPARLPLWACGAADLTVR-MQYTATSFAEPLQRVFGDVLRPDTDIE
MAV_5113|M.avium_104                RRRSDPVTLPLWACGADELTPR-MQYTATSFAEPLQRVFDDVLRPDTDIE
MMAR_1655|M.marinum_M               RHRPEPVTSPLWACGADELTAR-MECTPTSFAQPLQRVFDDVLRPDTGIE
MUL_1892|M.ulcerans_Agy99           RHRPEPVTSPLWACGADELTAR-MECTPTSFAQPLQRVFDDVRRPDTGIE
Mflv_0162|M.gilvum_PYR-GCK          RSRRFGAAPRVSDAGQPDIGLLPSSYNISPAAGEITWLRGSELRDPRHRS
                                                  .   :     .    .    :    .          

MSMEG_2052|M.smegmatis_MC2_155      -----------AMVTVDDKAVDGTAGGLAAL--VSRTSDALRQVQTGFAR
Mvan_1874|M.vanbaalenii_PYR-1       -----------GLVELDDDAVDGAAGGLAAG--VSRISEGLRQLQTGFAR
TH_1090|M.thermoresistible__bu      -----------TLVHVDEVGVDGVGSGLAAT--VRRFSEALRGLQTGFAR
MAB_2145|M.abscessus_ATCC_1997      -----------GMVLVDDRAVDGMVNGVASI--LGAVSGWVRQLQTGHVR
Rv0083|M.tuberculosis_H37Rv         VTHTAESRYMAERITYRTAVADAIEQRLYTP-VVGAVAAMAELLRRAHTG
Mb0086|M.bovis_AF2122/97            VTHTAESRYMAERITYRTAVADAIEQRLYTP-VVGAVAAMAELLRRAHTG
MAV_5113|M.avium_104                ITHLTESRYLAEAVTYRTRIADAIEERLYAP-VIGAVAAAAQLVRRAHTG
MMAR_1655|M.marinum_M               VTHLEATRYHVEQIAYRAHLSDAIEDRIYAP-VLRALAWCAQVIRRAHNG
MUL_1892|M.ulcerans_Agy99           VTHLEATRYHVEQIAYRAHLSDAIEDRVYAPVVLRALAWCAQVIRRAHNG
Mflv_0162|M.gilvum_PYR-GCK          LVLEVATRLIFPVMMVLSAYFFFAGHNVPGGGFAGGLMAGLALVLRYLAG
                                                 :             :               :      

MSMEG_2052|M.smegmatis_MC2_155      -----------------SYALSMLGGSALVVAAILAVQLW----------
Mvan_1874|M.vanbaalenii_PYR-1       -----------------SYALSMLAGAALVVAMILAVNLW----------
TH_1090|M.thermoresistible__bu      -----------------SYALSMLVGAALVVAMVLVVRAW----------
MAB_2145|M.abscessus_ATCC_1997      -----------------SYALSMCAGAAVVVAVLMAVRW-----------
Rv0083|M.tuberculosis_H37Rv         -----------------SVHRYLAYGALGVLIVLVVAR------------
Mb0086|M.bovis_AF2122/97            -----------------SVHRYLAYGALGVLIVLVVARCT----------
MAV_5113|M.avium_104                -----------------SVHLYLAYGMLGVLIVLVVAR------------
MMAR_1655|M.marinum_M               -----------------SVHLYLGYGALGVLIVLVVAR------------
MUL_1892|M.ulcerans_Agy99           -----------------SVHLYLGYGALGVLIVLVVAR------------
Mflv_0162|M.gilvum_PYR-GCK          GRYELGETLPLDAGKILGAGLALSAGTAVASLLLGAPALSSAVIEFDVPV
                                                     .    :  *   .   : .              

MSMEG_2052|M.smegmatis_MC2_155      --------------------------------------------------
Mvan_1874|M.vanbaalenii_PYR-1       --------------------------------------------------
TH_1090|M.thermoresistible__bu      --------------------------------------------------
MAB_2145|M.abscessus_ATCC_1997      --------------------------------------------------
Rv0083|M.tuberculosis_H37Rv         --------------------------------------------------
Mb0086|M.bovis_AF2122/97            --------------------------------------------------
MAV_5113|M.avium_104                --------------------------------------------------
MMAR_1655|M.marinum_M               --------------------------------------------------
MUL_1892|M.ulcerans_Agy99           --------------------------------------------------
Mflv_0162|M.gilvum_PYR-GCK          LGSVKFVTALFFDLGVYLIVVGLVLDVLRSLGARIDVELSEQRRQTDRTV
                                                                                      

MSMEG_2052|M.smegmatis_MC2_155      ---
Mvan_1874|M.vanbaalenii_PYR-1       ---
TH_1090|M.thermoresistible__bu      ---
MAB_2145|M.abscessus_ATCC_1997      ---
Rv0083|M.tuberculosis_H37Rv         ---
Mb0086|M.bovis_AF2122/97            ---
MAV_5113|M.avium_104                ---
MMAR_1655|M.marinum_M               ---
MUL_1892|M.ulcerans_Agy99           ---
Mflv_0162|M.gilvum_PYR-GCK          RQR