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MIGAHLASVLTPLPVLIPMLGAAATLIAGRRPRLQRAIVVSGLSAVVAVSAALLYLADRDGTIALQVGGW GPTEDGLGPLGVTLVVDRLSALMLVVSSIVLLAVVFYAIGQGIRDGDERQPVSIFLPTYLVLSAGVFMAF LAGDLFNLFVGFEVLLTASFVLLTIGASKERVRAGISYVMVSMVSSLVFLFGIALVYATTGTLNLAEIAV RLDDVPEGTRMALFAVLLVAFGIKAAVFPLSAWLPDSYPTAPAPVTAVFAGLLTKVGVYAIIRAHSLLFP GGGMDRILLVAGLLTMVIGIFGAIAQSDIKRLLSFTLVSHIGYMVFGIALSTQLGMAGAIYYVAHHILVQ TTLFLVVGLIERQAGASTLERLGGLAAASPLLAFVFVVPALNLGGIPPFSGFIGKVALLEAGAESGSVLA WILVAGSVITSLLTLYVVARVWTKAFWRARKDAPEGHLSGPAPTALLDNTDETMDIEHSDRDDVGRMPVG MLAPTGALIVVGLALTVLAGPIIAYSDRAAAEVLDRSQYIGAVLGGQP
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. gilvum PYR-GCK | Mflv_0164 | - | - | 100% (538) | putative monovalent cation/H+ antiporter subunit D |
M. gilvum PYR-GCK | Mflv_4494 | - | 5e-42 | 28.14% (501) | NADH dehydrogenase subunit N |
M. gilvum PYR-GCK | Mflv_4493 | - | 8e-37 | 25.00% (528) | NADH dehydrogenase subunit M |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb3180 | nuoL | 5e-38 | 29.83% (466) | NADH dehydrogenase subunit L |
M. tuberculosis H37Rv | Rv3156 | nuoL | 4e-38 | 29.83% (466) | NADH dehydrogenase subunit L |
M. leprae Br4923 | - | - | - | - | - |
M. abscessus ATCC 19977 | MAB_0634c | - | 0.0 | 80.79% (531) | putative monovalent cation/H+ antiporter subunit D |
M. marinum M | MMAR_1472 | nuoL | 2e-37 | 27.91% (455) | NADH dehydrogenase I (chain L) NuoL (NADH- ubiquinone |
M. avium 104 | MAV_4044 | - | 1e-40 | 29.01% (455) | NADH dehydrogenase subunit L |
M. smegmatis MC2 155 | MSMEG_0846 | - | 0.0 | 82.45% (530) | putative monovalent cation/H+ antiporter subunit D |
M. thermoresistible (build 8) | TH_4005 | - | 0.0 | 81.65% (534) | PUTATIVE NADH-ubiquinone oxidoreductase/multisubunit na+/h+ |
M. ulcerans Agy99 | MUL_2470 | nuoL | 8e-37 | 27.91% (455) | NADH dehydrogenase subunit L |
M. vanbaalenii PYR-1 | Mvan_0742 | - | 0.0 | 94.40% (536) | putative monovalent cation/H+ antiporter subunit D |
CLUSTAL 2.0.9 multiple sequence alignment Mb3180|M.bovis_AF2122/97 -----MTTSLG-------THYTWLLVALPLAGAAILLFGGRRTDAWGHLL Rv3156|M.tuberculosis_H37Rv -----MTTSLG-------THYTWLLVALPLAGAAILLFGGRRTDAWGHLL MMAR_1472|M.marinum_M -----MTNFLG-------TQHTWLLVALPLAGAAILLFGGRRTDAWGHWL MUL_2470|M.ulcerans_Agy99 -----MTNFLG-------TQHTWLLVALPLAGAAILLFGGRRTDAWGHWL MAV_4044|M.avium_104 -----MTRTYSKAEHANMTHYTPLLVALPLAGAAILLFGGRRTDRWGHWL Mflv_0164|M.gilvum_PYR-GCK MIGAHLAS-----------VLTPLPVLIPMLGAAATLIAGRRP-----RL Mvan_0742|M.vanbaalenii_PYR-1 MIGAQFAS-----------VLTPLPVLVPMLAAAATLIAGRRP-----RL MSMEG_0846|M.smegmatis_MC2_155 ----MMVQ-----------TLIPLPVLIPTLAAAATLIAGRRP-----HL TH_4005|M.thermoresistible__bu ---MNLAA-----------TLTPLPVLIPTLSAAATLIAGRRV-----RL MAB_0634c|M.abscessus_ATCC_199 ---MSTMS-----------VLTPLPVLVPTTAAALTLIAGRRP-----RL * * :* .** *:.*** * Mb3180|M.bovis_AF2122/97 GCAAALAAFGVGAMLLADMLGRDGLERAIHQQVFTWIPAGG--LQVDFGL Rv3156|M.tuberculosis_H37Rv GCAAALAAFGVGAMLLADMLGRDGLERAIHQQVFTWIPAGG--LQVDFGL MMAR_1472|M.marinum_M GCAAALASFGVGATMLADLVGRSADDRLIHQTVFTWMPVSQ--LQVDFGL MUL_2470|M.ulcerans_Agy99 GCAAALASFGVGATMLADLVGRSADDRLIHQTVFTWMPVSQ--LQVDFGL MAV_4044|M.avium_104 GCATAVAAFVVGVGLLDELLGRPADQRAIHERVFSWIPVGQ--LQVDLGL Mflv_0164|M.gilvum_PYR-GCK QRAIVVSGLSAVVAVSAALLYLADRDGTIALQVGGWGPTEDGLGPLGVTL Mvan_0742|M.vanbaalenii_PYR-1 QRSIVVLALSTVVAVSAALLYLADRDGTFALQVGGWGSTEAGMGPLGVTL MSMEG_0846|M.smegmatis_MC2_155 QRAIAQIALTAVVAVCGVLLYLSDRDGTLVLHVGGWDQAIPGMGPLGITL TH_4005|M.thermoresistible__bu QRMIALLSLTAMVAVCAVLLYLTDRDGTVVVHVGGWGEIVGGLGPLGITL MAB_0634c|M.abscessus_ATCC_199 QLLITVTALTTVLGVCTALLYLTDRDGTFALAVGGWGPTEEKLGPLGITL . .: . : :: : . * * :.. * Mb3180|M.bovis_AF2122/97 QIDQLSMCFVLLISGVGSLIHIYSVGYMAEDPDRRR----FFGYLNLFLA Rv3156|M.tuberculosis_H37Rv QIDQLSMCFVLLISGVGSLIHIYSVGYMAEDPDRRR----FFGYLNLFLA MMAR_1472|M.marinum_M QIDQLSICFVLLITGVGSLIHIYSVAYMAEDPDRRR----FFGYLNLFLA MUL_2470|M.ulcerans_Agy99 QIDQLSICFVLLITGVGSLIHIYSVAYMAEDPDRRR----FFGYLNLFLA MAV_4044|M.avium_104 QIDQLSVCFVLLITGVGSLIHIYSVAYMAEDADRRR----FFGYLNLFLA Mflv_0164|M.gilvum_PYR-GCK VVDRLSALMLVVSSIVLLAVVFYAIGQGIRDGDERQPVSIFLPTYLVLSA Mvan_0742|M.vanbaalenii_PYR-1 VVDRLSALMLVVSSIVLLAVVFYAIGQGIRDGDERQPVSIFLPTYLVLSA MSMEG_0846|M.smegmatis_MC2_155 VVDRLSALMLVVSSIVLLAVVVYAIGQGIRDGDERQPVSIFMPTYLVLSA TH_4005|M.thermoresistible__bu VVDRLAAMMLVVSSIVLLAVVQYAIGQGVRDGDERQPVSIFIPTYLVLSA MAB_0634c|M.abscessus_ATCC_199 VVDRLSALMLVVSAIVLLAVVLYAAAQGIRDGDERQPVSIFMPTYLALSA :*:*: :::: : * : *: . .* *.*: *: : * Mb3180|M.bovis_AF2122/97 SMLLLVVADNYVLLYVGWEGVGLASYLLIGFWYHKPSAATAAKKAFVMNR Rv3156|M.tuberculosis_H37Rv SMLLLVVADNYVLLYVGWEGVGLASYLLIGFWYHKPSAATAAKKAFVMNR MMAR_1472|M.marinum_M SMLLLVVADNYVLLYVGWEGVGLASYLLIGFWYHKPSAATAAKKAFVMNR MUL_2470|M.ulcerans_Agy99 SMLLLVVADNYVLLYVGWEGVGLASYLLIGFWYHKASAATAAKKAFVMNR MAV_4044|M.avium_104 SMLLLVIADNYVVLYVGWEGVGLASYLLIGFWYHKPTAATAAKKAFVMNR Mflv_0164|M.gilvum_PYR-GCK GVFMAFLAGDLFNLFVGFEVLLTASFVLLTIGASK-ERVRAGISYVMVSM Mvan_0742|M.vanbaalenii_PYR-1 GVFMAFLAGDLFNLFVGFEVLLTASFVLLTIGASK-ERVRAGISYVMVSM MSMEG_0846|M.smegmatis_MC2_155 GVYTAFLAGDLFNLFVGFEVLLAASFVLLTIGASA-DRVRAGISYVLVSM TH_4005|M.thermoresistible__bu GVCMAFVAGDLFNLFVGFEVLLTASFVLLTIGASE-ERVRAGTYYVMVSM MAB_0634c|M.abscessus_ATCC_199 GVCNAFLAGDLFNLYVGFEVLLAASFVLLTIGASA-DRVRAGISYVMVSM .: .:*.: . *:**:* : **::*: : . *. .::. Mb3180|M.bovis_AF2122/97 VGDAGLAVGMFLTFSTFGTLSYAGVFAGVPAASRAVLTAIGLLMLLGACA Rv3156|M.tuberculosis_H37Rv VGDAGLAVGMFLTFSTFGTLSYAGVFAGVPAASRAVLTAIGLLMLLGACA MMAR_1472|M.marinum_M VGDAGLALGMFVMFSTFGTLSYAGVFAGAPAASRGALTAMGLLLLLGACA MUL_2470|M.ulcerans_Agy99 VGDAGLALGMFVMFSTFGTLSYAGVFAGAPAASRGALTAMGLLLLLGACA MAV_4044|M.avium_104 VGDAGLALGMFLMFSTFGTLSYAGVFAGAPAAGRGALTAMGLLLLLGACA Mflv_0164|M.gilvum_PYR-GCK VSSLVFLFGIALVYATTGTLNLAEIAVRLDDVPEGTRMALFAVLLVAFGI Mvan_0742|M.vanbaalenii_PYR-1 VSSLVFLFGIALVYATTGTLNLAEIAVRLDDVPEGTRMALFAVLLVAFGI MSMEG_0846|M.smegmatis_MC2_155 VSSMIFLIGIALVYASTGTLNLAELGVRLTDLPPGTRTAIFAVLLVAFGI TH_4005|M.thermoresistible__bu VSSLIFLAGIGLVYAATGTLNMAELAVRLDDIAPGTRTALFAVLLIAFGI MAB_0634c|M.abscessus_ATCC_199 MSSVVFLLGIAFVYAATGTLNMAEIALRADGIPSGTRMAIFAVLLVGFAI :.. : *: . ::: ***. * : .. *: ::*:. Mb3180|M.bovis_AF2122/97 KSAQVPLQAWLGDAMEGPTPVSALIHAATMVTAGVYLIVRSGPLYNLAPT Rv3156|M.tuberculosis_H37Rv KSAQVPLQAWLGDAMEGPTPVSALIHAATMVTAGVYLIVRSGPLYNLAPT MMAR_1472|M.marinum_M KSAQVPLQAWLGDAMEGPTPVSALIHAATMVTAGVYLIVRSNPLYNLAPD MUL_2470|M.ulcerans_Agy99 KSAQVPLQAWLGDAMEGPTPVSALIHAATMVTAGVYLIVRSNLLYNLAPD MAV_4044|M.avium_104 KSAQVPLQAWLGDAMEGPTPVSALIHAATMVTAGVYLIVRSNPLYNLSPD Mflv_0164|M.gilvum_PYR-GCK KAAVFPLSAWLPDSYPTAPAPVTAVFAGLLTKVGVYAIIRAHSLLFPGGG Mvan_0742|M.vanbaalenii_PYR-1 KAAVFPLSAWLPDSYPTAPAPVTAVFAGLLTKVGVYAIIRAHSLLFPGGG MSMEG_0846|M.smegmatis_MC2_155 KAAVFPLSAWLPDSYPTAPAPVTAVFAGLLTKVGVYAIIRAHSLLFPDGG TH_4005|M.thermoresistible__bu KAAVFPLSSWLPDSYPTAPAPVTAVFAGLLTKVGVYAIIRTHSLLFPGAG MAB_0634c|M.abscessus_ATCC_199 KAAVFPLSTWLPDSYPTAPAPVTAVFAGLLTKVGVYAIIRAHSLLFPGGG *:* .**.:** *: ... : :.*. :...*** *:*: * Mb3180|M.bovis_AF2122/97 AQLAVVIVGAVTLLYGAIIGCAKDDIKRALAASTISQIGYMVLAAGLG-P Rv3156|M.tuberculosis_H37Rv AQLAVVIVGAVTLLFGAIIGCAKDDIKRALAASTISQIGYMVLAAGLG-P MMAR_1472|M.marinum_M AQLAVVVVGTVTLLLGAVIGCAKDDIKRALAASTMSQIGYMVLAAGLG-P MUL_2470|M.ulcerans_Agy99 AQLAVVVVGTVTLLLGGVIGCAKDDIKRALAASTMSQIGYMVLAAGLG-P MAV_4044|M.avium_104 AQLAVVIVGAVTLLLGAFIGCAKDDIKRALAASTMSQIGYMVLAAGLG-P Mflv_0164|M.gilvum_PYR-GCK MDRILLVAGLLTMVIGIFGAIAQSDIKRLLSFTLVSHIGYMVFGIALSTQ Mvan_0742|M.vanbaalenii_PYR-1 MDRVLLVAGLLTMIIGIFGAIAQSDIKRLLSFTLVSHIGYMVFGIALSTH MSMEG_0846|M.smegmatis_MC2_155 LDSVLLVAGLLTMVIGILGAIAQSDIKRLLSFTLVSHIGYMVFGIALGNE TH_4005|M.thermoresistible__bu LDPLLLIAALATMLIGILGAIAQSDIKRLLSFTLVSHIGYMVFGIALSTQ MAB_0634c|M.abscessus_ATCC_199 LNTVLLVAALLTMIVGILGAIAQSDIKRLLSFTLVSHIGYMIFGIALSNE : :::.. *:: * . . *:.**** *: : :*:****::. .*. Mb3180|M.bovis_AF2122/97 AGYAFAIMHLLTHGFFKAGLFLGSGAVIHAMHEEQDMRRYGGLRAALPVT Rv3156|M.tuberculosis_H37Rv AGYAFAIMHLLTHGFFKAGLFLGSGAVIHAMHEEQDMRRYGGLRAALPVT MMAR_1472|M.marinum_M AGYAFAIMHLLTHGFFKAGLFLGSGSVIHAMHEEQDMRRYGGLRAALPVT MUL_2470|M.ulcerans_Agy99 AGYAFAIMHLLTHGFFKAGLFLGSGSVIHAIHEEQDMRRYGGLRAALPVT MAV_4044|M.avium_104 AGYAFAIMHLLTHGFFKAGLFLGSGAVIHAMHEEQDMRRYGGLRAALPVT Mflv_0164|M.gilvum_PYR-GCK LGMAGAIYYVAHHILVQTTLFLVVG-LIERQAGASTLERLGGLAAASPLL Mvan_0742|M.vanbaalenii_PYR-1 LGMSGAIYYVAHHILVQTTLFLVVG-LIERQAGASTLERLGGLAAASPLL MSMEG_0846|M.smegmatis_MC2_155 LGMAGAIYYVAHHIVVQTTLFLVVG-LIERQAGASTLQRLGGLAAASPVL TH_4005|M.thermoresistible__bu LGMSGAIYYVAHHIVVQTTLFLVVG-LIERQAGASTLQRLGGLAAASPLL MAB_0634c|M.abscessus_ATCC_199 LGMSGAIYYVAHHIIVQTTLFLVVG-LIERQAGASSLNRLGGLAAASPLL * : ** :: * ..:: *** * :*. . :.* *** ** *: Mb3180|M.bovis_AF2122/97 FATFGLAYLAIIGVPPFAGFFSKDAIIEAALGAGGIRGSLLGGAALLGAG Rv3156|M.tuberculosis_H37Rv FATFGLAYLAIIGVPPFAGFFSKDAIIEAALGAGGIRGSLLGGAALLGAG MMAR_1472|M.marinum_M FVTFGLGYLAIIGVPPFAGFFSKDAIIEAALGAGDTRGYVLGGAALLGAG MUL_2470|M.ulcerans_Agy99 FVTFGLGYLAIIGVPPFAGFFSKDAIIEAALGAGDTRGYVLGGAALLGAG MAV_4044|M.avium_104 FVTFGLGYLAIIGVPPFAGFFSKDAIIEAALAAGGVRGYLLGGAALLGAG Mflv_0164|M.gilvum_PYR-GCK AFVFVVPALNLGGIPPFSGFIGKVALLEAGAESGSVLAWILVAGSVITSL Mvan_0742|M.vanbaalenii_PYR-1 AFVFVVPALNLGGIPPFSGFIGKVALLEAGAQSGSVLAWALVAGSVATSL MSMEG_0846|M.smegmatis_MC2_155 AFVWVVPALNLGGIPPFSGFIGKIALMEAGAANGSALAWTLVAGGVVTSL TH_4005|M.thermoresistible__bu AFVFVVPALNLGGIPPFSGFIGKVALMEAGAADGSVLAWTLVGGSVVTSL MAB_0634c|M.abscessus_ATCC_199 AFVFVVPALNLGGIPPFSGFIGKVALLEAGSLQGSVLAWALVAGGTITSL .: : * : *:***:**:.* *::**. *. . * ... : Mb3180|M.bovis_AF2122/97 VTAFYMTRVMLMTFFGEKRWTPGAHPHEAPAVMTWPMILLAVGSVFSGGL Rv3156|M.tuberculosis_H37Rv VTAFYMTRVMLMTFFGEKRWTPGAHPHEAPAVMTWPMILLAVGSVFSGGL MMAR_1472|M.marinum_M VTAFYMTRVMLMTFFGEKRWAPGAHPHEAPALMTWPMILLAFGSVFSGGL MUL_2470|M.ulcerans_Agy99 VTAFYMTRVMLMTFFGEKRWAPGAHPHEAPALMTWPMILLAFGSVFSGGL MAV_4044|M.avium_104 VTAFYMTRVMLMTFFGEKRWAPGSHPHEAPGLMTWPMILLAVGSVFSGGL Mflv_0164|M.gilvum_PYR-GCK LTLYVVARVWTKAFWRARKDAPEGHLSGPAPTALLDNTDETMDIEHSD-R Mvan_0742|M.vanbaalenii_PYR-1 LTLYVVARVWTKAFWRSRKDAPEGHLSGPAPAALLDNTDETMDIELAD-R MSMEG_0846|M.smegmatis_MC2_155 LTLYVVARVWTKAFWRTRADAPEGHLSQAAPAVLLD---DGEDIEYAD-R TH_4005|M.thermoresistible__bu LTLYVVARVWTKAFWRSRADAPEGHLSAAAPAVLLD---DIEDIEFAE-R MAB_0634c|M.abscessus_ATCC_199 LTLYAVARVWTKAFWRPRSDAPEGDLAAAAPTALLD---DAEDVAFVD-R :* : ::** :*: : :* .. .. . Mb3180|M.bovis_AF2122/97 LAVGGTLRHWLQPVVGSHEEATHALPTWVATTLALGVVAVGIAVAYRMYG Rv3156|M.tuberculosis_H37Rv LAVGGTLRHWLQPVVGSHEEATHALPTWVATTLALGVVAVGIAVAYRMYG MMAR_1472|M.marinum_M LAMGGTLQRWLEPVVGAHEEATHALPTWVSTTVALGVVAVGIAVAYRMYG MUL_2470|M.ulcerans_Agy99 LAMGGTLQRWLEPVGGAHEEATHALPTWVSTTVALGVVAVGIVVAYRMYG MAV_4044|M.avium_104 FAVGGTLQRWLEPVVGRHEEVTHAVPVWISTALALGVVAVGIAVAYRLYA Mflv_0164|M.gilvum_PYR-GCK DDVGRMPVGMLAPTG--------------------ALIVVGLALTVLAG- Mvan_0742|M.vanbaalenii_PYR-1 DDVGRMPVGMLAPTG--------------------ALIVVGLLLTILAG- MSMEG_0846|M.smegmatis_MC2_155 EGVGRMPIGMLIPTA--------------------ALIVVGLVLTVAAG- TH_4005|M.thermoresistible__bu RHVGRMPVSMLVPTG--------------------GLILVGLALTIFAG- MAB_0634c|M.abscessus_ATCC_199 ADVGRIPAGMLAPTL--------------------GLIAVGVALTIFAG- :* * *. .:: **: :: Mb3180|M.bovis_AF2122/97 TAPIPRVAPVRVSALTAAARADLYGDAFNEEVFMRPGAQLTNAVVAVDDA Rv3156|M.tuberculosis_H37Rv TAPIPRVAPVRVSALTAAARADLYGDAFNEEVFMRPGAQLTNAVVAVDDA MMAR_1472|M.marinum_M TAAIPRVAPVRVSVLTTAARADMYADAFNEEVFMRPGAQLTDAVVEVDNA MUL_2470|M.ulcerans_Agy99 TAAIPRVAPVRVSVLTTAARADMYADAFNEEVFMRPGAQLTDAVVEVDNA MAV_4044|M.avium_104 TAPIPRVAPLSVSPLTTAVRNDFYGDAFNEEVFMRPGAQLTHALVEVDDA Mflv_0164|M.gilvum_PYR-GCK ----PIIAYSDRAAAEVLDRSQYIGAVLGGQP------------------ Mvan_0742|M.vanbaalenii_PYR-1 ----PIFGYSDRAAGEVIDRGQYIGAVLGGTR------------------ MSMEG_0846|M.smegmatis_MC2_155 ----PIFAFSERAAAEVIDRGQYITAVLGETR------------------ TH_4005|M.thermoresistible__bu ----PIVAYSERAAEQVLDRGRYIGAVIGEAP------------------ MAB_0634c|M.abscessus_ATCC_199 ----PIIAISDRAAAEVRDRTVYISAVLGGAPR----------------- * .. : . * .:. Mb3180|M.bovis_AF2122/97 GVDGSVNALATLVSQTSNRLRQMQTGFARNYALSMLVGAVLVAAALLVVQ Rv3156|M.tuberculosis_H37Rv GVDGSVNALATLVSQTSNRLRQMQTGFARNYALSMLVGAVLVAAALLVVQ MMAR_1472|M.marinum_M GVDGSVNALAGLVSMTSNRLRRMQTGFARNYALSMLAGAVLVAAVLLAVQ MUL_2470|M.ulcerans_Agy99 GVDGSVNALAGLVSMTSNRLRLMQTGFARNYALSMLAGAVLVAAVLLAVQ MAV_4044|M.avium_104 GVDGSVNALAALVSATSNRLRGLQTGFARNYALSMLTGAVLVIALILAVR Mflv_0164|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_0742|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0846|M.smegmatis_MC2_155 -------------------------------------------------- TH_4005|M.thermoresistible__bu -------------------------------------------------- MAB_0634c|M.abscessus_ATCC_199 -------------------------------------------------- Mb3180|M.bovis_AF2122/97 LW Rv3156|M.tuberculosis_H37Rv LW MMAR_1472|M.marinum_M LW MUL_2470|M.ulcerans_Agy99 LW MAV_4044|M.avium_104 LW Mflv_0164|M.gilvum_PYR-GCK -- Mvan_0742|M.vanbaalenii_PYR-1 -- MSMEG_0846|M.smegmatis_MC2_155 -- TH_4005|M.thermoresistible__bu -- MAB_0634c|M.abscessus_ATCC_199 --