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M. thermoresistible (build 8) TH_1092 (nuoN)

annotation: PROBABLE NADH DEHYDROGENASE I (CHAIN N) NUON (NADH-UBIQUINONE OXIDOREDUCTASE CHAIN N)
coordinates: 2142879 - 2144426
length: 516

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_1092nuoN-100% (516)PROBABLE NADH DEHYDROGENASE I (CHAIN N) NUON (NADH-UBIQUINONE OXIDOREDUCTASE CHAIN N)
M. thermoresistible (build 8)TH_4005-4e-4027.75% (519) PUTATIVE NADH-ubiquinone oxidoreductase/multisubunit na+/h+
M. thermoresistible (build 8)TH_1091nuoM1e-3227.76% (508) PROBABLE NADH DEHYDROGENASE I (CHAIN M) NUOK

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb3182nuoN0.066.29% (528) NADH dehydrogenase subunit N
M. gilvum PYR-GCKMflv_4494-0.075.97% (516) NADH dehydrogenase subunit N
M. tuberculosis H37RvRv3158nuoN0.066.29% (528) NADH dehydrogenase subunit N
M. leprae Br4923-----
M. abscessus ATCC 19977MAB_2147-1e-17458.83% (532) NADH dehydrogenase subunit N
M. marinum MMMAR_1470nuoN0.066.41% (524) NADH dehydrogenase I (chain N) NuoN (NADH- ubiquinone
M. avium 104MAV_4047-0.067.56% (521) NADH dehydrogenase subunit N
M. smegmatis MC2 155MSMEG_2050nuoN0.078.49% (516) NADH dehydrogenase subunit N
M. ulcerans Agy99MUL_2472nuoN0.065.84% (524) NADH dehydrogenase subunit N
M. vanbaalenii PYR-1Mvan_1872-0.074.85% (517) NADH dehydrogenase subunit N

CLUSTAL 2.0.9 multiple sequence alignment


Mb3182|M.bovis_AF2122/97            ----MILPAPHVEYFLLAPMLIVFSVAVAGVLAEAFLPRRWRYGAQVTLA
Rv3158|M.tuberculosis_H37Rv         ----MILPAPHVEYFLLAPMLIVFSVAVAGVLAEAFLPRRWRYGAQVTLA
MMAR_1470|M.marinum_M               ----MILPSPSIEYFLLCPMLIVFGIAVIGVLAEAFLPRRLRYGAQVTLA
MUL_2472|M.ulcerans_Agy99           ----MILPSPSIEYFLLCPMLIVFGIAVVGVLAEAFLPRRLRYGAQVTLA
MAV_4047|M.avium_104                ---MMTLPTPSIQYFLLCPTLIVFGVAVAGVLAEAFLPRRIRYTAQVTLA
Mflv_4494|M.gilvum_PYR-GCK          MNTLTPLPTPTVEYFFLSPMLIVLGAAVLGVLVEALLPRHLRYRAQAGLS
Mvan_1872|M.vanbaalenii_PYR-1       MN----IPTPTVEYGLISPMLIVLAAAVLGVLVEAFVPRGRRYAVQVTLS
MSMEG_2050|M.smegmatis_MC2_155      ------MITPSIEYGLLSPMLIVFGVAIAGVLIEALAPRQSRYPLQVTLA
TH_1092|M.thermoresistible__bu      -----------VEYSLLLPMLIVFGVAIAGVLIEAFLPRRLRYRVQLTLT
MAB_2147|M.abscessus_ATCC_1997      MTDIGILPAPAIAYGALSPMLIMFGVAVVSVLVEAFVPRGHRLRTQLALA
                                               : *  : * **::. *: .** **: **  *   *  *:

Mb3182|M.bovis_AF2122/97            LGGSAVALIAVIVVARSIHGSG-HAAVLGAIAVDRATLFLQGTVLLVTIM
Rv3158|M.tuberculosis_H37Rv         LGGSAVALIAVIVVARSIHGSG-HAAVLGAIAVDRATLFLQGTVLLVTIM
MMAR_1470|M.marinum_M               LSGLVAAFVAVIVVARSIPVTG-RRAVLGSMAVDRPTLFLQGTVLLVAVM
MUL_2472|M.ulcerans_Agy99           LSGLVAAFVAVIVVARSIPVTG-RRAVLGSMAVDRPTLFLQGTVLLVEVM
MAV_4047|M.avium_104                LGGLVAALFAVIEVAESLPASG-RAAVLGAMAIDRPTLYLQGTVLLVAVM
Mflv_4494|M.gilvum_PYR-GCK          LAALLAAFVAVVMVARDLPADGAVSAVMGAVAVDMPALFLQGTILAVGVL
Mvan_1872|M.vanbaalenii_PYR-1       IAALVASFVAVVLVARDLHGGSGSEAVMGAIAVDMPALFLQGTILVVGVL
MSMEG_2050|M.smegmatis_MC2_155      LGGLIATVVAVVFVARGLSGTPGRPAVLGAVVLDAPAVFLQGTIALVGIL
TH_1092|M.thermoresistible__bu      LGGLVAALLAVLGLTDRLSGGGGDTAMMGAVVIDGPALFLQGTVVLLAIL
MAB_2147|M.abscessus_ATCC_1997      TVGILGAFVAVVALSGSH-----QVVMNGAVAIDGPTLYLQGLILVASGL
                                      .   :..**: ::          .: *::.:* .:::*** :     :

Mb3182|M.bovis_AF2122/97            AVVFMAERSARVSPQRQNTLAVARLPGLDSFTPQASAVPGSDAERQAERA
Rv3158|M.tuberculosis_H37Rv         AVVFMAERSARVSPQRQNTLAVARLPGLDSFTPQASAVPGSDAERQAERA
MMAR_1470|M.marinum_M               AVIFIAERSAHRVAAQTKTAVAAGSGGLDSFTPQASAVPGSDAEREAQRA
MUL_2472|M.ulcerans_Agy99           AVIFIAERSAHRVAAQTKTAVAAGSGGLDSFTPQASAVPGSDAEREAQRA
MAV_4047|M.avium_104                AVIFIAER--TQTKSDSKVAVVAGSGGLDSFTPQASAVPDSDAEREAERA
Mflv_4494|M.gilvum_PYR-GCK          GVLLIGER------QIGVVEDSENGRGLDAFTPQASAVAGSVAEKVAARA
Mvan_1872|M.vanbaalenii_PYR-1       GILLIGER------QISAPGPDTEGRGLEAFTPQASAVPGSVAEKLATRA
MSMEG_2050|M.smegmatis_MC2_155      GIMLIAER------QKATVSAG-EARGLEDFTPQASAVAGSVAEQLATKT
TH_1092|M.thermoresistible__bu      GVLLIAER------QIGS---RDPARGLDGFTPQASAVPGSVAEQVATRA
MAB_2147|M.abscessus_ATCC_1997      ALVVMAQR--RTVAAVPSAVGAGAGGGLDSFAAQASSVPGSEPERVLNRT
                                    .::.:.:*                  **: *:.***:*..* .*:   ::

Mb3182|M.bovis_AF2122/97            GATQTELFPLAMLSVGGMMVFPASNDLLTMFVALEVLSLPLYLMCGLARN
Rv3158|M.tuberculosis_H37Rv         GATQTELFPLAMLSVGGMMVFPASNDLLTMFVALEVLSLPLYLMCGLARN
MMAR_1470|M.marinum_M               GAAQTEIFPLLTLSVGGMMVFPAANDLLTMFVALEVLSLPLYLMCGLARH
MUL_2472|M.ulcerans_Agy99           GVAQTEIFPLLTLSVGGMMVFPAANDLLTMFVALEVLSLPLYLMCGLARH
MAV_4047|M.avium_104                GAAQTELFPLAMLSVGGMMVFPASNDLLTMFVALEVLSLPLYLMCGLARH
Mflv_4494|M.gilvum_PYR-GCK          GNIQTEVFPLTMFAVAGMLLFPAADDLLTMFIALEVLSLPLYLLCGMARR
Mvan_1872|M.vanbaalenii_PYR-1       GVIQTEVFPLTLFAIGGMLLFPAANDLLTMFIALEVLSLPLYLLCGLARR
MSMEG_2050|M.smegmatis_MC2_155      GVMQTEVFPLTMFAIGGMLLFPAADDLLTMFVALEVLSLPLYLLCGLARR
TH_1092|M.thermoresistible__bu      GAVQTEVFPLTMFATGGMMLFGASDDLLTIFVALEVLSLPLYLLCGLARR
MAB_2147|M.abscessus_ATCC_1997      GITQTEIFPLTLFAIAGMMLFPACNDLLTMFVALEVFSLPLYVMCALARR
                                    *  ***:***  :: .**::* *.:****:*:****:*****::*.:**.

Mb3182|M.bovis_AF2122/97            RRLLSQEAAMKYFLLGAFSSAFFLYGVALLYGATGTLTLPGIRDALAART
Rv3158|M.tuberculosis_H37Rv         RRLLSQEAAMKYFLLGAFSSAFFLYGVALLYGATGTLTLPGIRDALAART
MMAR_1470|M.marinum_M               RRLLSQESALKYFLLGAFSSAFFLYGVALLYGATGSLTLTGIRDSLTARS
MUL_2472|M.ulcerans_Agy99           RRLLSQESALKYFLLGAFSSAVFLYGVALLYGATDSLTLTGIRDSLAARS
MAV_4047|M.avium_104                RRLLSQEAAMKYFLLGAFSSAFFLYGVALLYGATGTLLLTGIRDALITRG
Mflv_4494|M.gilvum_PYR-GCK          RRLLSQESAVKYFLLGAFSSAFFLYGAAMLYGYAGTLSFPGIADAVADGT
Mvan_1872|M.vanbaalenii_PYR-1       RRLLSQEASLKYFLLGAFSSAIFLYGAAMLYGYAGTLQLDGIADAVAAGT
MSMEG_2050|M.smegmatis_MC2_155      RRLLSQEAALKYFLLGAFSSAFFIYGAAMLYGSAGTLDLSGIAESVAAGS
TH_1092|M.thermoresistible__bu      QRLLSQEAALKYFLLGAFSSAFFVYGVAMLYGYSGTLRLGGIADAVATPP
MAB_2147|M.abscessus_ATCC_1997      RRLLSQESALKYFLLGAFSSAFFLFGSAFVYGYAGTVELDAVARAVDADA
                                    :******:::***********.*::* *::** :.:: : .:  ::    

Mb3182|M.bovis_AF2122/97            D--DSMALAGVALLAVGLLFKVGAVPFHSWIPDVYQGAPTPITGFMAAAT
Rv3158|M.tuberculosis_H37Rv         D--DSMALAGVALLAVGLLFKVGAVPFHSWIPDVYQGAPTPITGFMAAAT
MMAR_1470|M.marinum_M               D--MSMALVGVGLLSVGLLFKVGAVPFHSWIPDVYQGAPTPITGFMAAAT
MUL_2472|M.ulcerans_Agy99           D--MSMALVGVGLLSVGLLFKVGAVPFHSWIPDVYQGAPTPTTGFMAAAT
MAV_4047|M.avium_104                D--TSLALVGVALLSVGLLFKVGAVPFHSWIPDVYQGAPTPITGFMAAAT
Mflv_4494|M.gilvum_PYR-GCK          G-TTSLGLIGVALLLVGILFKIGAVPFHSWIPDVYQGAPTPITAFMAAAT
Mvan_1872|M.vanbaalenii_PYR-1       G-RTSLALIGIALLLVGVLFKVGAVPFHSWIPDVYQGAPTPITAFMAAAT
MSMEG_2050|M.smegmatis_MC2_155      G-NTSLALLGVALLLVGVLFKVGAVPFHSWIPDVYQGAPTSITAFMAAAT
TH_1092|M.thermoresistible__bu      GGSTALALIGIGLLMVGLLFKVGAVPFHSWIPDAYQGAPTAITAFMSAAT
MAB_2147|M.abscessus_ATCC_1997      G-ERSFLLLGVAMLSVGLLFKVGAVPFHFWVPDVYQGAPTPVTAFMAATT
                                    .   :: * *:.:* **:***:****** *:**.******. *.**:*:*

Mb3182|M.bovis_AF2122/97            KVAAFGALLRVVYVALPPLHDQWRPVLWAIAILTMTVGTVTAVNQTNVKR
Rv3158|M.tuberculosis_H37Rv         KVAAFGALLRVVYVALPPLHDQWRPVLWAIAILTMTVGTVTAVNQTNVKR
MMAR_1470|M.marinum_M               KVAAFGALLRVVYVALPPLHDQWRPVLWAISILTMAVGTITAVNQTNVKR
MUL_2472|M.ulcerans_Agy99           KVAAFGALLRVVYVALPPLHDQWRPVLWAISILTMAVGTITAVNQTNVKR
MAV_4047|M.avium_104                KVAAFGALLRVVYVALPPLHDQWRPVLWTISILTMAVGTITAVNQSDVKR
Mflv_4494|M.gilvum_PYR-GCK          KIAAFGAMLRLFYVALPGLRDDWRPVLWAIAILTMVVGTVTAVTQTDVKR
Mvan_1872|M.vanbaalenii_PYR-1       KIAAFGAMLRLFYVALPGLRDDWRPVLWAIAILTMVVGTVTAVTQNDVKR
MSMEG_2050|M.smegmatis_MC2_155      KIAAFGAMLRIFYVAVPALRDDWRPVLWAIAILTMVVGTVTAVTQTDVKR
TH_1092|M.thermoresistible__bu      KVAAFGALLRICHVALPALKDDWRPMLWAVAILTMVVGTVTAVTQTDVKR
MAB_2147|M.abscessus_ATCC_1997      KIAAFGALLRVLYVALPGITTDWRPVLWGVAIATMLIGSIGAVTQTDVKR
                                    *:*****:**: :**:* :  :***:** ::* ** :*:: **.*.:***

Mb3182|M.bovis_AF2122/97            MLAYSSVAHVGFILTGVIADNPAGLSATLFYLVAYSFSTMGAFAIVGLVR
Rv3158|M.tuberculosis_H37Rv         MLAYSSVAHVGFILTGVIADNPAGLSATLFYLVAYSFSTMGAFAIVGLVR
MMAR_1470|M.marinum_M               MLAYSSVAHVGFILTGVIADNSAGLSATLFYLVAYSFSTVGAFAIVGLVR
MUL_2472|M.ulcerans_Agy99           MLAYSSVAHVGFILTGVIADNSAGLSATLFYLVAYSFSTVGAFAIVGLVR
MAV_4047|M.avium_104                MLAYSSVAHVGFILTGVIADNHTGLSATLFYLLAYSFSTVGAFAIVGLIR
Mflv_4494|M.gilvum_PYR-GCK          MLGYSAVAHTGFILTGVIAGNDAGVSSTLFYLFAYGFSTVGAFAVVGLVR
Mvan_1872|M.vanbaalenii_PYR-1       MLGYSAVAHSGFILTGVIAGSAAGLSSTLFYLFAYGFSTVGAFAVVSLVR
MSMEG_2050|M.smegmatis_MC2_155      MLAYSAVAHSGFILTGVIAANPAGVSSTLFYLFAYGFSTLGAFAVVGLIR
TH_1092|M.thermoresistible__bu      MLAYSAVAHTGFILTGVIAANEAGVSSTLFYLFAYGFSSLGAFALVGLVR
MAB_2147|M.abscessus_ATCC_1997      MLAYSAVAHTGFLLTGVAAANERGVSSTLFYLAAYGFSTVGAFIIAGLVR
                                    **.**:*** **:**** * .  *:*:***** **.**::*** :..*:*

Mb3182|M.bovis_AF2122/97            G------ADGSA--GSEDADLSHWAGLGQRSPIVGVMLSMFLLAFAGIPL
Rv3158|M.tuberculosis_H37Rv         G------ADGSA--GSEDADLSHWAGLGQRSPIVGVMLSMFLLAFAGIPL
MMAR_1470|M.marinum_M               D------ANG-----VEDANLSHWAGLGQRSPIVGVMLSMFLLAFAGIPL
MUL_2472|M.ulcerans_Agy99           D------ADG-----VEDANLSHWAGLGQRSPIVGVMLSMFLLAFAGIPL
MAV_4047|M.avium_104                D------ADG-----VEDATLSHWAGLGQRSPIVGVMFSMFLLAFAGIPL
Mflv_4494|M.gilvum_PYR-GCK          N------SDG-----EEDTAMARWAGLGKRYPLVGIVFSLFLLAFAGIPL
Mvan_1872|M.vanbaalenii_PYR-1       D------ADG-----EEDSAMARWAGLGKRYPVVGIVFSLFLLAFAGIPL
MSMEG_2050|M.smegmatis_MC2_155      N------AAG-----DEETSMAQWAGLGRRYPIVGVVFSLFLLAFAGIPL
TH_1092|M.thermoresistible__bu      S------RDG-----EEATSMAAWAGLGRRHPLAGVVFSLFLLAFAGIPL
MAB_2147|M.abscessus_ATCC_1997      SGNADDGADGDYKDDDEVTDLRRWAGVGRRAPVLGIVFALFLLAFAGIPL
                                    .        *      * : :  ***:*:* *: *:::::**********

Mb3182|M.bovis_AF2122/97            TSGFVSKFAVFRAAASAGAVPLVIVGVISSGVAAYFYVRVIVSMFFTEES
Rv3158|M.tuberculosis_H37Rv         TSGFVSKFAVFRAAASAGAVPLVIVGVISSGVAAYFYVRVIVSMFFTEES
MMAR_1470|M.marinum_M               TSGFISKFSVFKAAAEGGAAPLVVIGVISSGVAAYFYVRVIVLMFFTEES
MUL_2472|M.ulcerans_Agy99           TSGFISKFSVFKAAAEGGAAPLVVIGVISSGVAAYFYVRVIVLMFFTEES
MAV_4047|M.avium_104                TSGFVSKLAVFKAAAQGGAVPLVIVGVVASGVAAYFYVRVIVSMFFTEAT
Mflv_4494|M.gilvum_PYR-GCK          TSGFVGKFAVFKAAGEGGAIPLVVVGVVASAIAAYFYVRVIVLMFFTDSP
Mvan_1872|M.vanbaalenii_PYR-1       TSGFVSKFAVFKAAGEGGAIPLVVVGVIASAIAAYFYVRVIMLMFFTDRP
MSMEG_2050|M.smegmatis_MC2_155      TSGFVSKFAVFKAAGEGGAIPLVIIGVIASAVAAYFYVRVIVLMFFTEPP
TH_1092|M.thermoresistible__bu      TSGFVAKFAVFKAAGEGGAIPLVVIGVIASAVAAYFYVRVIVLMFFTDPP
MAB_2147|M.abscessus_ATCC_1997      TSGFVSKFAVFEAAAAGGAMPLVVVGVMCSAIAAYFYVRVIVVMFFADPV
                                    ****:.*::**.**. .** ***::**:.*.:*********: ***::  

Mb3182|M.bovis_AF2122/97            GDTPHVAAPGVLSKAAIAVCTVVTVVLGIAPQPVLDLADQAAQLLR
Rv3158|M.tuberculosis_H37Rv         GDTPHVAAPGVLSKAAIAVCTVVTVVLGIAPQPVLDLADQAAQLLR
MMAR_1470|M.marinum_M               SDTPQVVAPGILSKAAIAVCAAVTVLLGILPQPVLDLANQAAHLLH
MUL_2472|M.ulcerans_Agy99           SDTPQVVAPGILSKAAIAVCAAVTVLLGILPQPVLDLANQAAHLLH
MAV_4047|M.avium_104                EDTPHVVAPGILSKAAIAVCAAVTVALGVFPQPLLDLADQAAQLLH
Mflv_4494|M.gilvum_PYR-GCK          DDAPAVVVPSVLTTAVVTVTAAVTFMLGALPQPLLDLADSADRFF-
Mvan_1872|M.vanbaalenii_PYR-1       DDAPTVVVPSALTTAVVTVTAAVTFALGALPQPLLDLANAADRFL-
MSMEG_2050|M.smegmatis_MC2_155      DDAPELVVPSGLSTAVVTVTAAVTFALGALPQPLLDLANSAETFLH
TH_1092|M.thermoresistible__bu      SDAPEVVAPSGLTTAVVTVTAAVTFALGALPQPLLDLADSAVPFLR
MAB_2147|M.abscessus_ATCC_1997      EDSGVLRIPGPAVTVSIAVSALITVLLGVAPQPLLDLVENLADFVT
                                     *:  :  *.   .. ::* : :*. **  ***:***.:    :.