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QAGQRRGRWTGVPLEDRHAVRRDTLIAAGVQLLGEEAGPALTVRAVCRQAALTERYFYESFSDRDHFVRA VYDDVCTRAMATLMSANTPRDAVERFVALMVDDPVRGRVLLLAPAVEPVLTRSGADWMPNFIDLLQRKLS QIADPVLQKLVATSLIGALTGLFTAYLNGQLGATRQQFIDYCVDLLLGTAAAYAPHRDRGEAEHPVAARQ HD*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. ulcerans Agy99 | MUL_0446 | - | - | 100% (213) | hypothetical protein MUL_0446 |
| M. ulcerans Agy99 | MUL_1200 | - | 8e-17 | 31.44% (194) | TetR family transcriptional regulator |
| M. ulcerans Agy99 | MUL_4890 | - | 1e-06 | 33.04% (112) | transcriptional regulatory protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0848c | - | 1e-100 | 82.16% (213) | hypothetical protein Mb0848c |
| M. gilvum PYR-GCK | Mflv_1669 | - | 4e-75 | 70.68% (191) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv0825c | - | 1e-100 | 82.16% (213) | hypothetical protein Rv0825c |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_0756c | - | 2e-55 | 55.17% (203) | hypothetical protein MAB_0756c |
| M. marinum M | MMAR_4855 | - | 1e-119 | 99.53% (213) | hypothetical protein MMAR_4855 |
| M. avium 104 | MAV_0773 | - | 2e-81 | 77.60% (192) | hypothetical protein MAV_0773 |
| M. smegmatis MC2 155 | MSMEG_5768 | - | 3e-81 | 75.26% (194) | hypothetical protein MSMEG_5768 |
| M. thermoresistible (build 8) | TH_1575 | - | 4e-80 | 79.12% (182) | CONSERVED HYPOTHETICAL PROTEIN |
| M. vanbaalenii PYR-1 | Mvan_5084 | - | 1e-78 | 72.77% (191) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
MUL_0446|M.ulcerans_Agy99 MQAGQRRGR-WTGVPLEDRHAVRRDTLIAAGVQLLGEEAGPALTVRAVCR
MMAR_4855|M.marinum_M MQAGQRRGR-WTGVPLEDRHAVRRDTLIAAGVQLLGEEAGPALTVRAVCR
Mb0848c|M.bovis_AF2122/97 MQTGQNRGR-WSGVPLESRHALRRDNLVAAGVQLLGGAGGPALTVRAVCR
Rv0825c|M.tuberculosis_H37Rv MQTGQNRGR-WSGVPLESRHALRRDNLVAAGVQLLGGAGGPALTVRAVCR
MAV_0773|M.avium_104 -------------MPLESRLALRRDNLINAGVQLLGGSGGPALTVRAVCR
Mflv_1669|M.gilvum_PYR-GCK MPSGQRRGR-WSGVPLQDRQALRRDELITAGIGLLGSSGGPNLTVRAVCK
Mvan_5084|M.vanbaalenii_PYR-1 MPSGQRRGR-WSGVPLQDRQALRRDELITAGISLLGSPGGPHLTVRAVCK
TH_1575|M.thermoresistible__bu -------------VPLSDRQTLRREELIAAGVKLLGHREGPALTVRAVCR
MSMEG_5768|M.smegmatis_MC2_155 MPSGQRRGR-WSGVPLRERTALRRDELIAAGVKLLGAADGPALTVRAVCR
MAB_0756c|M.abscessus_ATCC_199 MANGQAQRRSWAGVSPAERADERRRELMAAGVRLLGLRPRPAVTVRAVCR
:. .* ** *: **: *** * :******:
MUL_0446|M.ulcerans_Agy99 QAALTERYFYESFSDRDHFVRAVYDDVCTRAMATLMSANTPRDAVERFVA
MMAR_4855|M.marinum_M QAALTERYFYESFSDRDHFVRAVYDDVCTRAMATLMSANTPRDAVERFVA
Mb0848c|M.bovis_AF2122/97 HAGLTERYFYESFADREHFVRAVYDDVCTRAMATLTSAQTPREAVEQFVE
Rv0825c|M.tuberculosis_H37Rv HAGLTERYFYESFADREHFVRAVYDDVCTRAMATLTSAQTPREAVEQFVE
MAV_0773|M.avium_104 KAALTERYFYESFTDRDEFVRAVYDDVCTRAMNTLTSATTPREAVERFVE
Mflv_1669|M.gilvum_PYR-GCK AAGLTERYFYESFTDRDEYVAAVYDDVCTAAMATLRESESMRDAVERFVA
Mvan_5084|M.vanbaalenii_PYR-1 AAGLTERYFYESFTDRDEYVAAVYDNVCTAAMSTLMKSDSMRDAVERFVA
TH_1575|M.thermoresistible__bu EAGLTERYFYESFADRDEFVRAVYDDVCARAMSTLMTADTPRDAVERFVA
MSMEG_5768|M.smegmatis_MC2_155 EAGLTERYFYECFNDRDGFVRAVYDDVCATAMSALTAADTPRKAVEQFVS
MAB_0756c|M.abscessus_ATCC_199 SAGMTERYFYEHFSDRDTFVRAVYDHVGFRAIEALSGVRSAYEGVDAFAR
*.:******* * **: :* ****.* *: :* : ..*: *.
MUL_0446|M.ulcerans_Agy99 LMVDDPVRGRVLLLAPAVEPVLTRSGADWMPNFIDLLQRKLSQ-IADPVL
MMAR_4855|M.marinum_M LMVDDPVRGRVLLLAPAVEPVLTRSGADWMPNFIDLLQRKLSQ-IADPVL
Mb0848c|M.bovis_AF2122/97 LMVDDPVRGRVLLLAPAVEPALTRSGAEWMPNFIELLQRKLSR-IVDPVL
Rv0825c|M.tuberculosis_H37Rv LMVDDPVRGRVLLLAPAVEPALTRSGAEWMPNFIELLQRKLSR-IVDPVL
MAV_0773|M.avium_104 LMVDDPVRGRVLLLAPAVEPVLTRSGAEWMPNFIDLLQRKLSR-IGDAVL
Mflv_1669|M.gilvum_PYR-GCK LMIDDPARGRVLLLAPEAEPVLARSGARWMPNFIELLQHNLTR-ITDTTT
Mvan_5084|M.vanbaalenii_PYR-1 LMIDDPARGRVLLLAPEVEPVLARSGARWMPNFIDLLQRNLTQ-ISDPTT
TH_1575|M.thermoresistible__bu LMVDDPVRGRVLLLAPEVEPVLTRSGAKWMPNFIDLLQRKLTR-ITDPAL
MSMEG_5768|M.smegmatis_MC2_155 LMVDDPTRGRVLLLAPESEPVLTRSGAEWMPNFIDLLQRKLTR-IADPVR
MAB_0756c|M.abscessus_ATCC_199 LMVDEPTMGRVLLIAPTFEPTLSESGYDWLPRFVALLQGKLSTNLADEVQ
**:*:*. *****:** **.*:.** *:*.*: *** :*: : * .
MUL_0446|M.ulcerans_Agy99 QKLVATSLIGALTGLFTAYLNGQLGATRQQFIDYCVDLLLGTAAAYAPHR
MMAR_4855|M.marinum_M QKLVATSLIGALTGLFTAYLNGQLGATRQQFIDYCVDLLLGTAAAYAPHR
Mb0848c|M.bovis_AF2122/97 QKLVATSLIGALTGLFTAYLNGRLGATRKQFIDYCVNMLLSTAATYAPHR
Rv0825c|M.tuberculosis_H37Rv QKLVATSLIGALTGLFTAYLNGRLGATRKQFIDYCVNMLLSTAATYAPHR
MAV_0773|M.avium_104 QKMIATSLVGGLSSLFTAYLHGQLGATRKQFIDYCTNMLYITAAPYVSAG
Mflv_1669|M.gilvum_PYR-GCK QAMVATGLIGALTALFTAYLDGRLEATREQFIDHCAELLLSRAVT-----
Mvan_5084|M.vanbaalenii_PYR-1 QAMVATGLIGALTALFTAYLDGRLGATRERFIDHCAELLLSRAVT-----
TH_1575|M.thermoresistible__bu QAMVATGLIGALTALFTAYLDGRLAATREQFIDYCVGILLNPVASY----
MSMEG_5768|M.smegmatis_MC2_155 QAMVATSLIGALTALFTAYLNDRLPATREQFIDFCVDMLLGRVGSF----
MAB_0756c|M.abscessus_ATCC_199 QQLVATSLVGALTSLFTAYLNEELNVDRQRFVDYCVQILLQGANASVTPR
* ::**.*:*.*:.******. .* . *::*:*.*. :* . .
MUL_0446|M.ulcerans_Agy99 DRGEAEHPVAARQHD
MMAR_4855|M.marinum_M DRGEAERPVAARQHD
Mb0848c|M.bovis_AF2122/97 ERGESEHSIPAGPHN
Rv0825c|M.tuberculosis_H37Rv ERGESEHSIPAGPHN
MAV_0773|M.avium_104 ELGKSQ---------
Mflv_1669|M.gilvum_PYR-GCK ---------------
Mvan_5084|M.vanbaalenii_PYR-1 ---------------
TH_1575|M.thermoresistible__bu ---------------
MSMEG_5768|M.smegmatis_MC2_155 ---------------
MAB_0756c|M.abscessus_ATCC_199 PTSPSPQQPS-----