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aa seq not available
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. thermoresistible (build 8) | TH_3611 | - | - | 100% (413) | putative cytochrome P450 |
| M. thermoresistible (build 8) | TH_2643 | - | 0.0 | 77.19% (399) | PUTATIVE putative cytochrome P450 superfamily protein |
| M. thermoresistible (build 8) | TH_2944 | - | 3e-87 | 44.09% (381) | PUTATIVE cytochrome P450 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0801 | cyp126 | 4e-43 | 32.76% (348) | cytochrome P450 126 |
| M. gilvum PYR-GCK | Mflv_4150 | - | 5e-94 | 46.86% (382) | cytochrome P450 |
| M. tuberculosis H37Rv | Rv3518c | cyp142 | 3e-43 | 34.58% (321) | cytochrome P450 monooxygenase 142 |
| M. leprae Br4923 | MLBr_02088 | - | 2e-37 | 27.46% (397) | putative cytochrome p450 |
| M. abscessus ATCC 19977 | MAB_3825 | - | 2e-43 | 34.56% (298) | cytochrome P450 |
| M. marinum M | MMAR_4008 | cyp187A5 | 7e-84 | 42.86% (392) | cytochrome P450 187A5 Cyp187A5 |
| M. avium 104 | MAV_1274 | - | 2e-96 | 48.31% (385) | cytochrome P450 superfamily protein |
| M. smegmatis MC2 155 | MSMEG_2240 | - | 5e-83 | 42.48% (379) | cytochrome P450 |
| M. ulcerans Agy99 | MUL_3872 | cyp187A5 | 3e-84 | 42.71% (391) | cytochrome P450 187A5 Cyp187A5 |
| M. vanbaalenii PYR-1 | Mvan_2007 | - | 9e-81 | 42.06% (378) | cytochrome P450 |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_4008|M.marinum_M ---------MTSPVHSVAGTGDQAVNPR---NPYPFFAQQRRRGG-----
MUL_3872|M.ulcerans_Agy99 ---------MTSPVHSVAGTGDQAVNPR---NPYPFFAQQRRRGG-----
MSMEG_2240|M.smegmatis_MC2_155 ---------MDSRIRDDPAV-DTAALLR---DPYPIFARYRAQAG-----
Mvan_2007|M.vanbaalenii_PYR-1 ---------METPVQD-LAK-DEPIDLR---DPYPMFARRRAEGG-----
TH_3611|M.thermoresistible__bu MVEPTGVKDPDQSIREAQARFNTGMGADGDASPYPLLRELRAQGA-----
Mflv_4150|M.gilvum_PYR-GCK -------MSQLFEDLEDFGSFDDAVSGDVR-DPYPELARLRREEP-----
MAV_1274|M.avium_104 -------MEQLFDDLEDFGAFDDAVSGDVR-DPYTELARLRREEP-----
Rv3518c|M.tuberculosis_H37Rv -------MTEAPDVDLADGNFYASREAR------AAYRWMRANQP-----
Mb0801|M.bovis_AF2122/97 -------MTTAAGLSGIDLTDLDNFADG---FPHHLFAIHRREAP-----
MAB_3825|M.abscessus_ATCC_1997 ------MATALSEIEEAGRVLADPAAYADELRLHAAMTLLRREQP-----
MLBr_02088|M.leprae_Br4923 -MRTCVPTRTCVYAFIEYLSHNRPMGTNPPSLVEAQMLLLRLIDPGTRAD
*
MMAR_4008|M.marinum_M VFPGTVMDYSKTPASLRPRREFSAMSFAAVNTVFRDSRAFTS--KTYDK-
MUL_3872|M.ulcerans_Agy99 VFPGTVMDYSKTPESLRPRREFSAMSFAAVNTVFRDSRAFTS--KTYDK-
MSMEG_2240|M.smegmatis_MC2_155 VFRGSVMDWSKTPKELMPEHQYAAMSFDAVNTVFRDGKTFNS--KIYDS-
Mvan_2007|M.vanbaalenii_PYR-1 VFRGSVMDWSRTPDSLRPENLYAAVSFDAVNRVFRDGKVFNS--HIYDS-
TH_3611|M.thermoresistible__bu VHAG-WPEMGMFGNSGDGPPTFTAYTFDTVKAILTDNVTFST--RCYAD-
Mflv_4150|M.gilvum_PYR-GCK IQR---IDMSAMPGE-EGKPVFIVYRYEDAQQMLRDNVTFSS--SGVIA-
MAV_1274|M.avium_104 IQR---LDTSGMPHE-ESKPVFIVYRHEDAQQMLRDNETFSS--AAVIA-
Rv3518c|M.tuberculosis_H37Rv VFR-------------DRNGLAAASTYQAVIDAERQPELFSN--AGGIR-
Mb0801|M.bovis_AF2122/97 VYWH-----RPTEHTPDGEGFWSVATYAETLEVLRDPVTYSS--VTGGQR
MAB_3825|M.abscessus_ATCC_1997 VTKVITDDYRPFWAVTKHDDIMAVERDNALWINEPRPLLMNL--EQEAEL
MLBr_02088|M.leprae_Br4923 PFPVYRALIDYGPMQLPGMPLTVFSSFSDCDEALRHPLSASDRLKATLAQ
.
MMAR_4008|M.marinum_M ------TIGLFMGP-TILAMEGKQHRDHRNLVSAAFKSKALARWEPAVIR
MUL_3872|M.ulcerans_Agy99 ------MIGLFMGP-TILAMEGKQHRDHRNLVSAAFKSKALARWEPAVIR
MSMEG_2240|M.smegmatis_MC2_155 ------TIGLFIGP-SILAMEGKTHRDHRNLVSAAFKSKSLARWEPEIAR
Mvan_2007|M.vanbaalenii_PYR-1 ------TIGLFIGP-TILAMEGKTHWEHRNLVSAAFKTRSLARWEPEIVR
TH_3611|M.thermoresistible__bu ------VVRPLQGP-TILEMQEPEHAVYRRLHEFAFARSSMKRWDAELVG
Mflv_4150|M.gilvum_PYR-GCK ------AFGPVLGERVMLGMDEPVHGRLRSLVSKAFSQKGLARWQDELVG
MAV_1274|M.avium_104 ------AFGPVLGERVMLGMDEPVHGRLRSLVSKAFSQKALARWEDELVG
Rv3518c|M.tuberculosis_H37Rv ------PDQPALPM--MIDMDDPAHLLRRKLVNAGFTRKRVKDKEASIA-
Mb0801|M.bovis_AF2122/97 RFGGTVLQDLPVAGQVLNMMDDPRHTRIRRLVSSGLTPRMIRRVEDDLRR
MAB_3825|M.abscessus_ATCC_1997 D----KQAAMGIELKTLVHIDDPKHRVLRAIGADWFRPKAMRDMKLRTDE
MLBr_02088|M.leprae_Br4923 QAIAAGAEPRPFYASSFMFLDPPDHTRLRKLVSKAFAPKVVQALEGDIAA
: :: * * : : : .
MMAR_4008|M.marinum_M PICNALIDDFIDAGRAELVGDFTFEFPTRVIARLLGLPDEDLAMFHQRAV
MUL_3872|M.ulcerans_Agy99 PICNALIDDFIDAGRAELVGDFTFEFPTRVIARLLGLPDEDLAMFHQRAV
MSMEG_2240|M.smegmatis_MC2_155 PICEALVDEFVDTGSADLVRDYTFEFPTRVISKLLGLPEEDLPWFRRRAV
Mvan_2007|M.vanbaalenii_PYR-1 PVVNELIDEFIDDGRADLVRDFTFEFPTRVISRLLGLPEEDLPWFRKRAV
TH_3611|M.thermoresistible__bu PLVARTIRKFKDAKRIDLVSAVFMPIPVRVIAALLGLPETDVPAFHRLAI
Mflv_4150|M.gilvum_PYR-GCK RVGNELIDRFQADGKADLVKQFTFDYPSRIIAGLLGLPEQDYPQFQRWSI
MAV_1274|M.avium_104 RVGNSLIDRFAGNGKADLVKEFTFDYPSRIIAGLLGLPEQDYPQFQRWSI
Rv3518c|M.tuberculosis_H37Rv ALCDTLIDAVCERGECDFVRDLAAPLPMAVIGDMLGVRPEQRDMFLRWSD
Mb0801|M.bovis_AF2122/97 RARG-LLDGVEPGAPFDFVVEIAAELPMQMICILLGVPETDRHWLFEAVE
MAB_3825|M.abscessus_ATCC_1997 LANRYVNKLLEAGGSCDFAQDIAVHFPLYVIMSLLGIPESDFDRMLKLTQ
MLBr_02088|M.leprae_Br4923 LVDS-LLDKGAAAGQFDVIADLAFPLAVAVICRLLGVPYEDAPEFGRVSA
:. . :* :**: : : .
MMAR_4008|M.marinum_M QLISYT-----------VNYQLAFEASAALKEYFLEQIDRRRSKPSEDII
MUL_3872|M.ulcerans_Agy99 QLISYT-----------VNYQLAFEASAALKEYFLEQIDRRRSKPSEDII
MSMEG_2240|M.smegmatis_MC2_155 ELISYS-----------VKYKRAFEASAALKDYFLDQIERRRSRPTEDII
Mvan_2007|M.vanbaalenii_PYR-1 ELISYA-----------VNYKKAFEASAALKDYFLGQIDKRRSAPTEDII
TH_3611|M.thermoresistible__bu DLLGFR-----------ADMDRALKASAEMKEYFVEILADKRRTPGDDMV
Mflv_4150|M.gilvum_PYR-GCK SLLSWI-----------LNPERGLAAAAALCEYFAPILEARRTDPQDDLI
MAV_1274|M.avium_104 SLLSWI-----------LNPQRGLAASAALCDYFAPILAARRTEPKDDLI
Rv3518c|M.tuberculosis_H37Rv DLVTFLSSHVSQ-----EDFQITMDAFAAYNDFTRATIAARRADPTDDLV
Mb0801|M.bovis_AF2122/97 PGFDFRGSRRAT-----MPRLNVEDAGSRLYTYALELIAGKRAEPADDML
MAB_3825|M.abscessus_ATCC_1997 ELFGGDDSEFQRG----TTPEEQLMALLDFFGYFSGLTASRRQHPTDDLA
MLBr_02088|M.leprae_Br4923 LLVQSVDPFITITGEPPEATEERLRAGVWLRDYLEQLVKCRRGTPGEDLI
. * : :* * :*:
MMAR_4008|M.marinum_M GDLVTAEID---GEKLSEEAIYSFLRLLLPAGLETTYRSSGNLLYLLLAH
MUL_3872|M.ulcerans_Agy99 GDLVTAEID---GEKLSEEAIYSFLRLLLPAGLETTYRSSGNLLYLLLAH
MSMEG_2240|M.smegmatis_MC2_155 GDLVTAEID---GEKLTDEAIYSFLRLLLPAGLETTYRSSGNLLYLLLTH
Mvan_2007|M.vanbaalenii_PYR-1 GDLVSAEID---GERLTDEAIFSFLRLLLPAGLETTFRSSGNLLYLLLTH
TH_3611|M.thermoresistible__bu SILAGAEID---GARMSDEQIYGFMRNLLPAGAETTARSTASLALGLLTH
Mflv_4150|M.gilvum_PYR-GCK SLLAEAEID---GEKLTDEEIFSFLRLLLPAGVETTYRSLGNLLFALLSD
MAV_1274|M.avium_104 SGLAQAEID---GEKLEDEEIYSFLRLLLPAGVETTYRALGSLLLALLSD
Rv3518c|M.tuberculosis_H37Rv SVLVSSEVD---GERLSDDELVMETLLILIGGDETTRHTLSGGTEQLLRN
Mb0801|M.bovis_AF2122/97 SVVANATIDDPDAPALSDAELYLFFHLLFSAGAETTRNSIAGGLLALAEN
MAB_3825|M.abscessus_ATCC_1997 STIANARVD---GELLSDVDTASYYTIIATAGHDTTSATIAGGLEALLEH
MLBr_02088|M.leprae_Br4923 SRLIELDES---GDQLTEEEIIATCGLLLVAGHETTVNLIANAVLAMLRN
. : . . : : : .* :** .. : .
MMAR_4008|M.marinum_M PDQFMAVRAHRELIPQAIEEGLRFETPLTTVQRFTTKDTEVQGVPIPARS
MUL_3872|M.ulcerans_Agy99 PDQFMAVRAHRELIPQAIEEGLRFETPLTTVQRFTTKDTEVQGVPIPARS
MSMEG_2240|M.smegmatis_MC2_155 PDQFAAVQNDHDLIGAAIEEGLRYETPLTTVQRSATKDTELEGVQIPAGA
Mvan_2007|M.vanbaalenii_PYR-1 RDQFEAVNADHALIGAAIEEGLRYETPLTTVQRFANEDTEIDGVEIPAGS
TH_3611|M.thermoresistible__bu PRQLDAVRADRSLLPQAIEEGIRWETPLLNFMRAVTRDTEIGGVQVPQGA
Mflv_4150|M.gilvum_PYR-GCK TAQLDAVRADRSLLPQAIEEGVRWNPPLLTITRTTTCDTELGGVPIPAGC
MAV_1274|M.avium_104 PEQLDAIRGDRSLLPQAIEEGVRWEPPLLTITRVATRDTELGGVPIPAGS
Rv3518c|M.tuberculosis_H37Rv RDQWDLLQRDPSLLPGAIEEMLRWTAPVKNMCRVLTADTEFHGTALCAGE
Mb0801|M.bovis_AF2122/97 PDQLQTLRSDFELLPTAIEEIVRWTSPSPSKRRTASRAVSLGGQPIEAGQ
MAB_3825|M.abscessus_ATCC_1997 PDQLARLRENPGLMPLAVDEMIRWVTPVKEFMRTATADTEIRGVPITEGE
MLBr_02088|M.leprae_Br4923 PSQWKALSSNPQRAPLVVEETLRYDPAIHLIGRVAAKDMTIGQTTLTEGD
* : . .::* :*: .. * . :
MMAR_4008|M.marinum_M VIGVCMGSANRDEHRWQRPEVFDIFRERIPHISFAAGEHTCLGLHLARLE
MUL_3872|M.ulcerans_Agy99 VIGVCMGSANRDEHRWQRPEVFDIFRERIPHISFAAGEHTCLGLHLARLE
MSMEG_2240|M.smegmatis_MC2_155 VIDVCIGSANRDENRWERPEEFDIFRKRIPHITFAAGEHTCMGLHLARME
Mvan_2007|M.vanbaalenii_PYR-1 VIDVCIGSANRDESRWERAEQFDIFRTRTPHISFAAGEHTCMGLHLARME
TH_3611|M.thermoresistible__bu TMMLNLGSANHDETRWDDPESFDIFRERKPHIGFGHGAHVCLGMHLARLE
Mflv_4150|M.gilvum_PYR-GCK SVLPMLGSTNRQEDRWEDPDEFNLFRAQKANLGWGYGVHVCLGMHLARLE
MAV_1274|M.avium_104 TVMPMLGAANRQEDRYPDPDRFDIFRAPKSHLGWGHGVHVCLGMHLARLE
Rv3518c|M.tuberculosis_H37Rv KMMLLFESANFDEAVFCEPEKFDVQRNPNSHLAFGFGTHFCLGNQLARLE
Mb0801|M.bovis_AF2122/97 KVVVWEGSANRDPSVFDRADEFDITRKPNPHLGFGQGVHYCLGANLARLE
MAB_3825|M.abscessus_ATCC_1997 SVLLSYPSGNRDEDIFTDPFTFDIARDPNKHLAFGFGVHFCLGAALARME
MLBr_02088|M.leprae_Br4923 TMVLLLAAANRDPAVYSRPDEFDPDRPSSRHLAFAVGSHFCLGAALARLE
: : * : : . *: * :: :. * * *:* ***:*
MMAR_4008|M.marinum_M TRVALECLLDRLTNIDLATAD-DPHIHGQPFRS-PTALPVTFEAVPT--
MUL_3872|M.ulcerans_Agy99 TRVALECLLDRLTNIDLATAD-DPHIHGQPFRS-PKALPVTFEAVPT--
MSMEG_2240|M.smegmatis_MC2_155 TRVAMETLLNRVTDLRLIADD-DPHIFGQPFRS-PTAIPVTFRPAG---
Mvan_2007|M.vanbaalenii_PYR-1 TRVAAETLLSRLSAIELLTDG-DPHIHGQPFRS-PTALPVTFTPSRARP
TH_3611|M.thermoresistible__bu TTKIFNALFDELPNLRLDPDAPEPYVSGLMFRS-PPRLDVIWD------
Mflv_4150|M.gilvum_PYR-GCK MRTAVNLLLDRLPGLRLDPDGDDPHIRGQVFRS-PTSLPVLFDAVGSDA
MAV_1274|M.avium_104 MRTAVNLLLDRLPNLRLDPDADDPHIRGQVFRS-PTSVPVLFDPQ----
Rv3518c|M.tuberculosis_H37Rv LSLMTERVLRRLPDLRLVADDSVLPLRPANFVSGLESMPVVFTPSPPLG
Mb0801|M.bovis_AF2122/97 LRVLFEELLSRFGSVRVVEPAEWTRSNRHTGIR---HLVVELRGG----
MAB_3825|M.abscessus_ATCC_1997 VNSFFSALLPRLESIEVDGNIERTST---IFVGGIKHLPIRYTLR----
MLBr_02088|M.leprae_Br4923 ATVTLSAISARFPQVQLAGELVYKPNVAMRGMS---ALPVQV-------
. : .. : : : :