For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
aa seq not available
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. thermoresistible (build 8) | TH_2643 | - | - | 100% (405) | putative cytochrome P450 superfamily protein |
| M. thermoresistible (build 8) | TH_3611 | - | 0.0 | 77.19% (399) | PUTATIVE putative cytochrome P450 |
| M. thermoresistible (build 8) | TH_2944 | - | 5e-97 | 47.66% (384) | PUTATIVE cytochrome P450 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0801 | cyp126 | 6e-47 | 33.87% (375) | cytochrome P450 126 |
| M. gilvum PYR-GCK | Mflv_4339 | - | 8e-94 | 47.38% (382) | cytochrome P450 |
| M. tuberculosis H37Rv | Rv0778 | cyp126 | 6e-47 | 33.87% (375) | cytochrome P450 126 |
| M. leprae Br4923 | MLBr_02088 | - | 2e-39 | 28.61% (374) | putative cytochrome p450 |
| M. abscessus ATCC 19977 | MAB_3825 | - | 2e-45 | 34.68% (297) | cytochrome P450 |
| M. marinum M | MMAR_4008 | cyp187A5 | 6e-94 | 46.45% (394) | cytochrome P450 187A5 Cyp187A5 |
| M. avium 104 | MAV_1598 | - | 4e-98 | 48.30% (383) | cytochrome P450 superfamily protein |
| M. smegmatis MC2 155 | MSMEG_2240 | - | 1e-96 | 48.03% (381) | cytochrome P450 |
| M. ulcerans Agy99 | MUL_3872 | cyp187A5 | 2e-94 | 46.08% (395) | cytochrome P450 187A5 Cyp187A5 |
| M. vanbaalenii PYR-1 | Mvan_2007 | - | 2e-94 | 47.38% (382) | cytochrome P450 |
CLUSTAL 2.0.9 multiple sequence alignment
Mb0801|M.bovis_AF2122/97 --------------MTTAAGLSGIDLTDLDNFADGFPHHLFAIHRREAPV
Rv0778|M.tuberculosis_H37Rv --------------MTTAAGLSGIDLTDLDNFADGFPHHLFAIHRREAPV
Mflv_4339|M.gilvum_PYR-GCK -----------MRVDTPVQD-VEM-DGPIDLR---DPYPMFARHRAEGGV
Mvan_2007|M.vanbaalenii_PYR-1 -------------METPVQD-LAK-DEPIDLR---DPYPMFARRRAEGGV
MSMEG_2240|M.smegmatis_MC2_155 -------------MDSRIRDDPAV-DTAALLR---DPYPIFARYRAQAGV
MMAR_4008|M.marinum_M -------------MTSPVHSVAGTGDQAVNPR---NPYPFFAQQRRRGGV
MUL_3872|M.ulcerans_Agy99 -------------MTSPVHSVAGTGDQAVNPR---NPYPFFAQQRRRGGV
MAV_1598|M.avium_104 -------------MTTNVPTAAGG--ETVSLR---DPYPFFARKRREAGV
TH_2643|M.thermoresistible__bu ------------VITAGVKEAQARFDAGMGADGDASPYPMLAELRSKAPV
MAB_3825|M.abscessus_ATCC_1997 ----------MATALSEIEEAGRVLADPAAYADELRLHAAMTLLRREQPV
MLBr_02088|M.leprae_Br4923 MRTCVPTRTCVYAFIEYLSHNRPMGTNPPSLVEAQMLLLRLIDPGTRADP
: .
Mb0801|M.bovis_AF2122/97 YWHRPTEHT-----PDGEGFWSVATYAETLEVLRDPVTYSSVTGGQRRFG
Rv0778|M.tuberculosis_H37Rv YWHRPTEHT-----PDGEGFWSVATYAETLEVLRDPVTYSSVTGGQRRFG
Mflv_4339|M.gilvum_PYR-GCK FRGSVMDWS-----KTPESLMPEKLYAAVSFDAVNRVFRDGKVFNSKIYD
Mvan_2007|M.vanbaalenii_PYR-1 FRGSVMDWS-----RTPDSLRPENLYAAVSFDAVNRVFRDGKVFNSHIYD
MSMEG_2240|M.smegmatis_MC2_155 FRGSVMDWS-----KTPKELMPEHQYAAMSFDAVNTVFRDGKTFNSKIYD
MMAR_4008|M.marinum_M FPGTVMDYS-----KTPASLRPRREFSAMSFAAVNTVFRDSRAFTSKTYD
MUL_3872|M.ulcerans_Agy99 FPGTVMDYS-----KTPESLRPRREFSAMSFAAVNTVFRDSRAFTSKTYD
MAV_1598|M.avium_104 FAGTVMDYS-----KTPESLMPKQEYSAVSFDAVNTVFRDGRVFSSKPYD
TH_2643|M.thermoresistible__bu HPG-WPEMS-----IFENPPDGPQTFAAYSFDAVKAVFTDNRTFSTRCYE
MAB_3825|M.abscessus_ATCC_1997 TKVITDDYRPFWAVTKHDDIMAVERDNALWINEPRPLLMNLEQEAELDKQ
MLBr_02088|M.leprae_Br4923 FPVYRALIDYGPMQLPGMPLTVFSSFSDCDEALRHPLSASDRLKATLAQQ
: .
Mb0801|M.bovis_AF2122/97 GTVLQD--LPVAGQVLNMMDDPRHTRIRRLVSSGLTPRMIRRVEDDLRR-
Rv0778|M.tuberculosis_H37Rv GTVLQD--LPVAGQVLNMMDDPRHTRIRRLVSSGLTPRMIRRVEDDLRR-
Mflv_4339|M.gilvum_PYR-GCK ATIG-----LFIGPTILAMEGKPHWEHRNLVSAAFKTRSLARWEPEIVRP
Mvan_2007|M.vanbaalenii_PYR-1 STIG-----LFIGPTILAMEGKTHWEHRNLVSAAFKTRSLARWEPEIVRP
MSMEG_2240|M.smegmatis_MC2_155 STIG-----LFIGPSILAMEGKTHRDHRNLVSAAFKSKSLARWEPEIARP
MMAR_4008|M.marinum_M KTIG-----LFMGPTILAMEGKQHRDHRNLVSAAFKSKALARWEPAVIRP
MUL_3872|M.ulcerans_Agy99 KMIG-----LFMGPTILAMEGKQHRDHRNLVSAAFKSKALARWEPAVIRP
MAV_1598|M.avium_104 KTIG-----LFMGPTILAMEGKKHRDHRNLVSAAFKSKALARWEPTIVRP
TH_2643|M.thermoresistible__bu AIVR-----PLQGPTILEMQEPEHQTYRRLHEFAFARSSMRRWEAELVRP
MAB_3825|M.abscessus_ATCC_1997 AAMG------IELKTLVHIDDPKHRVLRAIGADWFRPKAMRDMKLRTDEL
MLBr_02088|M.leprae_Br4923 AIAAGAEPRPFYASSFMFLDPPDHTRLRKLVSKAFAPKVVQALEGDIAA-
. : :: * * : : : :
Mb0801|M.bovis_AF2122/97 RARGLLDGVEPGAPFDFVVEIAAELPMQMICILLGVPETDRHWLFEAVEP
Rv0778|M.tuberculosis_H37Rv RARGLLDGVEPGAPFDFVVEIAAELPMQMICILLGVPETDRHWLFEAVEP
Mflv_4339|M.gilvum_PYR-GCK VVNGLIDEFIDRGSADLVRDFTFEFPTRVISRLLGLPEDDLPWFRKRAVE
Mvan_2007|M.vanbaalenii_PYR-1 VVNELIDEFIDDGRADLVRDFTFEFPTRVISRLLGLPEEDLPWFRKRAVE
MSMEG_2240|M.smegmatis_MC2_155 ICEALVDEFVDTGSADLVRDYTFEFPTRVISKLLGLPEEDLPWFRRRAVE
MMAR_4008|M.marinum_M ICNALIDDFIDAGRAELVGDFTFEFPTRVIARLLGLPDEDLAMFHQRAVQ
MUL_3872|M.ulcerans_Agy99 ICNALIDDFIDAGRAELVGDFTFEFPTRVIARLLGLPDEDLAMFHQRAVQ
MAV_1598|M.avium_104 ICNALIDDFIDAGTADLVRQFTFEFPTRVIARLLGLPDEDLPMFHTRAVQ
TH_2643|M.thermoresistible__bu LVERTVDRIRDAGRADLVEEVFMPIPVRVIAALLGLPEADVPEFHRLAID
MAB_3825|M.abscessus_ATCC_1997 ANRYVNKLLEAGGSCDFAQDIAVHFPLYVIMSLLGIPESDFDRMLKLTQE
MLBr_02088|M.leprae_Br4923 LVDSLLDKGAAAGQFDVIADLAFPLAVAVICRLLGVPYEDAPEFGRVSAL
. . :. : :. :* ***:* * :
Mb0801|M.bovis_AF2122/97 GFDFR-----GSRRATMPRLNVEDAGSRLYTYALELIAGKRAEPADDMLS
Rv0778|M.tuberculosis_H37Rv GFDFR-----GSRRATMPRLNVEDAGSRLYTYALELIAGKRAEPADDMLS
Mflv_4339|M.gilvum_PYR-GCK LISYT-----INHKRAF------EASAALKDYFLAQIEKRRCAPTDDIIG
Mvan_2007|M.vanbaalenii_PYR-1 LISYA-----VNYKKAF------EASAALKDYFLGQIDKRRSAPTEDIIG
MSMEG_2240|M.smegmatis_MC2_155 LISYS-----VKYKRAF------EASAALKDYFLDQIERRRSRPTEDIIG
MMAR_4008|M.marinum_M LISYT-----VNYQLAF------EASAALKEYFLEQIDRRRSKPSEDIIG
MUL_3872|M.ulcerans_Agy99 LISYT-----VNYQLAF------EASAALKEYFLEQIDRRRSKPSEDIIG
MAV_1598|M.avium_104 LISYH-----VDYERAF------EASAALKDYFLEQIEQRKSKPTEDIIG
TH_2643|M.thermoresistible__bu LLGFH-----ADMDTAL------KASAELRDYFVGILAERRRSPRDDMVS
MAB_3825|M.abscessus_ATCC_1997 LFGGDD----SEFQRGTTPEEQLMALLDFFGYFSGLTASRRQHPTDDLAS
MLBr_02088|M.leprae_Br4923 LVQSVDPFITITGEPPEATEERLRAGVWLRDYLEQLVKCRRGTPGEDLIS
. * : * :: * :*: .
Mb0801|M.bovis_AF2122/97 VVANATIDDPDAPALSDAELYLFFHLLFSAGAETTRNSIAGGLLALAENP
Rv0778|M.tuberculosis_H37Rv VVANATIDDPDAPALSDAELYLFFHLLFSAGAETTRNSIAGGLLALAENP
Mflv_4339|M.gilvum_PYR-GCK DLVSAEID---GEHLTDEAIFSFLRLLLPAGLETTYRSSGNLLYLLLTHR
Mvan_2007|M.vanbaalenii_PYR-1 DLVSAEID---GERLTDEAIFSFLRLLLPAGLETTFRSSGNLLYLLLTHR
MSMEG_2240|M.smegmatis_MC2_155 DLVTAEID---GEKLTDEAIYSFLRLLLPAGLETTYRSSGNLLYLLLTHP
MMAR_4008|M.marinum_M DLVTAEID---GEKLSEEAIYSFLRLLLPAGLETTYRSSGNLLYLLLAHP
MUL_3872|M.ulcerans_Agy99 DLVTAEID---GEKLSEEAIYSFLRLLLPAGLETTYRSSGNLLYLLLAHP
MAV_1598|M.avium_104 DLVTAEID---GEKLSDEAIYSFLRLLLPAGLETTYRSSGNLLYLLLTHP
TH_2643|M.thermoresistible__bu KLAHAEVD---GVRMSDEQIYGFMRNLLPAGAETTSRSTASLAYGLLTHP
MAB_3825|M.abscessus_ATCC_1997 TIANARVD---GELLSDVDTASYYTIIATAGHDTTSATIAGGLEALLEHP
MLBr_02088|M.leprae_Br4923 RLIELDES---GDQLTEEEIIATCGLLLVAGHETTVNLIANAVLAMLRNP
: . . ::: : ** :** .. : :
Mb0801|M.bovis_AF2122/97 DQLQTLRSDFELLPTAIEEIVRWTSPSPSKRRTASRAVSLGGQPIEAGQK
Rv0778|M.tuberculosis_H37Rv DQLQTLRSDFELLPTAIEEIVRWTSPSPSKRRTASRAVSLGGQPIEAGQK
Mflv_4339|M.gilvum_PYR-GCK DQFDAVDADHELIGQAIEEGLRYETPLTTVQRFTTEDTELEGVPIPAGAV
Mvan_2007|M.vanbaalenii_PYR-1 DQFEAVNADHALIGAAIEEGLRYETPLTTVQRFANEDTEIDGVEIPAGSV
MSMEG_2240|M.smegmatis_MC2_155 DQFAAVQNDHDLIGAAIEEGLRYETPLTTVQRSATKDTELEGVQIPAGAV
MMAR_4008|M.marinum_M DQFMAVRAHRELIPQAIEEGLRFETPLTTVQRFTTKDTEVQGVPIPARSV
MUL_3872|M.ulcerans_Agy99 DQFMAVRAHRELIPQAIEEGLRFETPLTTVQRFTTKDTEVQGVPIPARSV
MAV_1598|M.avium_104 DQFAALQADRELLAPAIEEGLRFETPLTTVQRFTTEDTELHGVRIPARSV
TH_2643|M.thermoresistible__bu DQLTAVKADRDLLPQAIEEGIRWETPLLNFMREVTEDIEFFGVQIPAGST
MAB_3825|M.abscessus_ATCC_1997 DQLARLRENPGLMPLAVDEMIRWVTPVKEFMRTATADTEIRGVPITEGES
MLBr_02088|M.leprae_Br4923 SQWKALSSNPQRAPLVVEETLRYDPAIHLIGRVAAKDMTIGQTTLTEGDT
.* : . .::* :*: .. * . . :
Mb0801|M.bovis_AF2122/97 VVVWEGSANRDPSVFDRADEFDITRKPNPHLGFGQGVHYCLGANLARLEL
Rv0778|M.tuberculosis_H37Rv VVVWEGSANRDPSVFDRADEFDITRKPNPHLGFGQGVHYCLGANLARLEL
Mflv_4339|M.gilvum_PYR-GCK IDVCIGSANRDEKRWERSEEFDIFRKRVPHLSFAAGEHTCMGLHLARMET
Mvan_2007|M.vanbaalenii_PYR-1 IDVCIGSANRDESRWERAEQFDIFRTRTPHISFAAGEHTCMGLHLARMET
MSMEG_2240|M.smegmatis_MC2_155 IDVCIGSANRDENRWERPEEFDIFRKRIPHITFAAGEHTCMGLHLARMET
MMAR_4008|M.marinum_M IGVCMGSANRDEHRWQRPEVFDIFRERIPHISFAAGEHTCLGLHLARLET
MUL_3872|M.ulcerans_Agy99 IGVCMGSANRDEHRWQRPEVFDIFRERIPHISFAAGEHTCLGLHLARLET
MAV_1598|M.avium_104 IGVCIGSANRDERRWERSEEFDIFRKHVPHISFAAGEHTCLGLHLARLET
TH_2643|M.thermoresistible__bu IAVNLGSANHDETRWERPEEFDIFRERKPHIGFGHGAHVCLGMHLARLES
MAB_3825|M.abscessus_ATCC_1997 VLLSYPSGNRDEDIFTDPFTFDIARDPNKHLAFGFGVHFCLGAALARMEV
MLBr_02088|M.leprae_Br4923 MVLLLAAANRDPAVYSRPDEFDPDRPSSRHLAFAVGSHFCLGAALARLEA
: : :.*:* : . ** * *: *. * * *:* ***:*
Mb0801|M.bovis_AF2122/97 RVLFEELLSRFGSVRVVEPAE--WTRSNRHTGIRHLVVELRGG----
Rv0778|M.tuberculosis_H37Rv RVLFEELLSRFGSVRVVEPAE--WTRSNRHTGIRHLVVELRGG----
Mflv_4339|M.gilvum_PYR-GCK RVAVETLLTRLSDIRLVTDDD-PHIHGQPFRSPTALPVTFSPAAAK-
Mvan_2007|M.vanbaalenii_PYR-1 RVAAETLLSRLSAIELLTDGD-PHIHGQPFRSPTALPVTFTPSRARP
MSMEG_2240|M.smegmatis_MC2_155 RVAMETLLNRVTDLRLIADDD-PHIFGQPFRSPTAIPVTFRPAG---
MMAR_4008|M.marinum_M RVALECLLDRLTNIDLATADD-PHIHGQPFRSPTALPVTFEAVPT--
MUL_3872|M.ulcerans_Agy99 RVALECLLDRLTNIDLATADD-PHIHGQPFRSPKALPVTFEAVPT--
MAV_1598|M.avium_104 RVAMECLLNRLTNVTLLSDGD-PHIHGQPFRSPTALPVTFDAK----
TH_2643|M.thermoresistible__bu TVIFNTLLDRLPGLRLDPDAAAPYVAGMYFRSPPYLHVVWD------
MAB_3825|M.abscessus_ATCC_1997 NSFFSALLPRLESIEVDGNIE--RTSTIFVGGIKHLPIRYTLR----
MLBr_02088|M.leprae_Br4923 TVTLSAISARFPQVQLAGELV--YKPNVAMRGMSALPVQV-------
. : *. : : . : :