For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
aa seq not available
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. thermoresistible (build 8) | TH_2944 | - | - | 100% (396) | cytochrome P450 |
| M. thermoresistible (build 8) | TH_2643 | - | 5e-97 | 47.66% (384) | PUTATIVE putative cytochrome P450 superfamily protein |
| M. thermoresistible (build 8) | TH_3611 | - | 2e-87 | 44.09% (381) | PUTATIVE putative cytochrome P450 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0789c | cyp123 | 5e-43 | 29.49% (390) | cytochrome P450 123 |
| M. gilvum PYR-GCK | Mflv_4339 | - | 1e-175 | 78.12% (384) | cytochrome P450 |
| M. tuberculosis H37Rv | Rv3518c | cyp142 | 3e-47 | 35.84% (332) | cytochrome P450 monooxygenase 142 |
| M. leprae Br4923 | MLBr_02088 | - | 4e-39 | 30.03% (303) | putative cytochrome p450 |
| M. abscessus ATCC 19977 | MAB_4456 | - | 1e-41 | 34.87% (304) | putative cytochrome P450 |
| M. marinum M | MMAR_4008 | cyp187A5 | 1e-166 | 73.96% (384) | cytochrome P450 187A5 Cyp187A5 |
| M. avium 104 | MAV_1598 | - | 1e-175 | 78.33% (383) | cytochrome P450 superfamily protein |
| M. smegmatis MC2 155 | MSMEG_2240 | - | 1e-177 | 76.73% (391) | cytochrome P450 |
| M. ulcerans Agy99 | MUL_3872 | cyp187A5 | 1e-165 | 73.70% (384) | cytochrome P450 187A5 Cyp187A5 |
| M. vanbaalenii PYR-1 | Mvan_2007 | - | 1e-173 | 76.17% (386) | cytochrome P450 |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_4339|M.gilvum_PYR-GCK ---------------------------MRVDTPVQD-VEM-DGPIDLRDP
Mvan_2007|M.vanbaalenii_PYR-1 -----------------------------METPVQD-LAK-DEPIDLRDP
MSMEG_2240|M.smegmatis_MC2_155 -----------------------------MDSRIRDDPAV-DTAALLRDP
TH_2944|M.thermoresistible__bu ------------------------------------MTAA-KPAGYLRDP
MMAR_4008|M.marinum_M -----------------------------MTSPVHSVAGTGDQAVNPRNP
MUL_3872|M.ulcerans_Agy99 -----------------------------MTSPVHSVAGTGDQAVNPRNP
MAV_1598|M.avium_104 -----------------------------MTTNVPTAAGG--ETVSLRDP
Mb0789c|M.bovis_AF2122/97 ---------------------------MTVRVGDPELVLDPYDYDFHEDP
Rv3518c|M.tuberculosis_H37Rv ------------------------------MTEAPDVDLADGNFYASREA
MAB_4456|M.abscessus_ATCC_1997 ----MRTRDQIKYWSRWATMHGISRAALLTQVRTLPLAALFLGPDRAEKH
MLBr_02088|M.leprae_Br4923 MRTCVPTRTCVYAFIEYLSHNRPMGTNPPSLVEAQMLLLRLIDPGTRADP
.
Mflv_4339|M.gilvum_PYR-GCK YPMFARHRAEGGVFRGSVMDWSKTPESLMPEKLYAAVSFDAVNRVFRD--
Mvan_2007|M.vanbaalenii_PYR-1 YPMFARRRAEGGVFRGSVMDWSRTPDSLRPENLYAAVSFDAVNRVFRD--
MSMEG_2240|M.smegmatis_MC2_155 YPIFARYRAQAGVFRGSVMDWSKTPKELMPEHQYAAMSFDAVNTVFRD--
TH_2944|M.thermoresistible__bu YPFFAERRRGSGVFHGTVIDYSRTPESLRPTDGYAAMSFDAVNRVLRD--
MMAR_4008|M.marinum_M YPFFAQQRRRGGVFPGTVMDYSKTPASLRPRREFSAMSFAAVNTVFRD--
MUL_3872|M.ulcerans_Agy99 YPFFAQQRRRGGVFPGTVMDYSKTPESLRPRREFSAMSFAAVNTVFRD--
MAV_1598|M.avium_104 YPFFARKRREAGVFAGTVMDYSKTPESLMPKQEYSAVSFDAVNTVFRD--
Mb0789c|M.bovis_AF2122/97 YPYYRRLRDEAPLYRNEERNFWAVSRHHDVLQGFRDS------TALSN--
Rv3518c|M.tuberculosis_H37Rv RAAYRWMRANQPVFRDR-------------NGLAAASTYQAVIDAERQ--
MAB_4456|M.abscessus_ATCC_1997 YRYIEEIRASGSVTPSRAGGLIFTDLALTREILRDNRFITMAPTNIPSPI
MLBr_02088|M.leprae_Br4923 FPVYRALIDYGPMQLPGMPLTVFSSFSDCDEALRHPLSASDRLKATLA--
:
Mflv_4339|M.gilvum_PYR-GCK -----GKVFNSKIYDATIGLFIGPTILAMEGKPHWEHRNLVSAAFKTRSL
Mvan_2007|M.vanbaalenii_PYR-1 -----GKVFNSHIYDSTIGLFIGPTILAMEGKTHWEHRNLVSAAFKTRSL
MSMEG_2240|M.smegmatis_MC2_155 -----GKTFNSKIYDSTIGLFIGPSILAMEGKTHRDHRNLVSAAFKSKSL
TH_2944|M.thermoresistible__bu -----GRVFSSALYDTTIGLFTGPTLLAMEGGTHRAHRNLISAAFKTKAL
MMAR_4008|M.marinum_M -----SRAFTSKTYDKTIGLFMGPTILAMEGKQHRDHRNLVSAAFKSKAL
MUL_3872|M.ulcerans_Agy99 -----SRAFTSKTYDKMIGLFMGPTILAMEGKQHRDHRNLVSAAFKSKAL
MAV_1598|M.avium_104 -----GRVFSSKPYDKTIGLFMGPTILAMEGKKHRDHRNLVSAAFKSKAL
Mb0789c|M.bovis_AF2122/97 -----AYGVSLDPSSRTSEAYRVMSMLAMDDPAHLRMRTLVSKGFTPRRI
Rv3518c|M.tuberculosis_H37Rv -----PELFSNAG-GIRPDQPALPMMIDMDDPAHLLRRKLVNAGFTRKRV
MAB_4456|M.abscessus_ATCC_1997 LPLAFSRWVFARTEPGLPNPVEPPAMLAVDPPEHTRFRKLVSKAFTPRAV
MLBr_02088|M.leprae_Br4923 --------QQAIAAGAEPRPFYASSFMFLDPPDHTRLRKLVSKAFAPKVV
:: :: * *.*:. .* : :
Mflv_4339|M.gilvum_PYR-GCK ARWEPEIVRPVVNGLIDEFIDRGSADLVRDFTFEFPTRVISRLLGLPEDD
Mvan_2007|M.vanbaalenii_PYR-1 ARWEPEIVRPVVNELIDEFIDDGRADLVRDFTFEFPTRVISRLLGLPEED
MSMEG_2240|M.smegmatis_MC2_155 ARWEPEIARPICEALVDEFVDTGSADLVRDYTFEFPTRVISKLLGLPEED
TH_2944|M.thermoresistible__bu ARWEPSIVRPIVNALIDEFIDTGTADLVRDFTFEFPTRVISRMLGLPEED
MMAR_4008|M.marinum_M ARWEPAVIRPICNALIDDFIDAGRAELVGDFTFEFPTRVIARLLGLPDED
MUL_3872|M.ulcerans_Agy99 ARWEPAVIRPICNALIDDFIDAGRAELVGDFTFEFPTRVIARLLGLPDED
MAV_1598|M.avium_104 ARWEPTIVRPICNALIDDFIDAGTADLVRQFTFEFPTRVIARLLGLPDED
Mb0789c|M.bovis_AF2122/97 RELEPQVLELAR-IHLDSALQTESFDFVAEFAGKLPMDVISELIGVPDTD
Rv3518c|M.tuberculosis_H37Rv KDKE-ASIAALCDTLIDAVCERGECDFVRDLAAPLPMAVIGDMLGVRPEQ
MAB_4456|M.abscessus_ATCC_1997 SKLEDRVREVTT-ELLDNLERHERADLLHDYASQLPVAIIAEMLGVPRAD
MLBr_02088|M.leprae_Br4923 QALEGDIAALVD-SLLDKGAAAGQFDVIADLAFPLAVAVICRLLGVPYED
* :* :.: : : :. :* ::*: :
Mflv_4339|M.gilvum_PYR-GCK LPWFRKRAVELIS-----------YTINHKRAFEASAALKDYFLAQIEKR
Mvan_2007|M.vanbaalenii_PYR-1 LPWFRKRAVELIS-----------YAVNYKKAFEASAALKDYFLGQIDKR
MSMEG_2240|M.smegmatis_MC2_155 LPWFRRRAVELIS-----------YSVKYKRAFEASAALKDYFLDQIERR
TH_2944|M.thermoresistible__bu LPTFRRWAVQLIS-----------YTVDYQRAFEASAALKDYFLEQMESR
MMAR_4008|M.marinum_M LAMFHQRAVQLIS-----------YTVNYQLAFEASAALKEYFLEQIDRR
MUL_3872|M.ulcerans_Agy99 LAMFHQRAVQLIS-----------YTVNYQLAFEASAALKEYFLEQIDRR
MAV_1598|M.avium_104 LPMFHTRAVQLIS-----------YHVDYERAFEASAALKDYFLEQIEQR
Mb0789c|M.bovis_AF2122/97 RARIRALADAVLHRED-------GVADVPPPAMAASIELMRYYADLIAEF
Rv3518c|M.tuberculosis_H37Rv RDMFLRWSDDLVTFLS-----SHVSQEDFQITMDAFAAYNDFTRATIAAR
MAB_4456|M.abscessus_ATCC_1997 APFLLEWGNHGAALLD-----IGMTWSAYRDATQALIEIDRYFDAHLVRL
MLBr_02088|M.leprae_Br4923 APEFGRVSALLVQSVDPFITITGEPPEATEERLRAGVWLRDYLEQLVKCR
: . * : :
Mflv_4339|M.gilvum_PYR-GCK RCAPTDD-IIGDLVSAEIDGEHLTDEAIFSFLRLLLPAGLETTYRSSGNL
Mvan_2007|M.vanbaalenii_PYR-1 RSAPTED-IIGDLVSAEIDGERLTDEAIFSFLRLLLPAGLETTFRSSGNL
MSMEG_2240|M.smegmatis_MC2_155 RSRPTED-IIGDLVTAEIDGEKLTDEAIYSFLRLLLPAGLETTYRSSGNL
TH_2944|M.thermoresistible__bu RSKPTDD-MIGDLVTAEIDGEKLSDEAIYSFLRLLLPAGLETTYRSSGNL
MMAR_4008|M.marinum_M RSKPSED-IIGDLVTAEIDGEKLSEEAIYSFLRLLLPAGLETTYRSSGNL
MUL_3872|M.ulcerans_Agy99 RSKPSED-IIGDLVTAEIDGEKLSEEAIYSFLRLLLPAGLETTYRSSGNL
MAV_1598|M.avium_104 KSKPTED-IIGDLVTAEIDGEKLSDEAIYSFLRLLLPAGLETTYRSSGNL
Mb0789c|M.bovis_AF2122/97 RRRPANN-LTSALLAAELDGDRLSDQEIMAFLFLMVIAGNETTTKLLANA
Rv3518c|M.tuberculosis_H37Rv RADPTDD-LVSVLVSSEVDGERLSDDELVMETLLILIGGDETTRHTLSGG
MAB_4456|M.abscessus_ATCC_1997 RGELAEDPTVDGILASIVRDGDLNDRELKATMALLLGAGFETTVNLIGNG
MLBr_02088|M.leprae_Br4923 RGTPGED-LISRLIELDESGDQLTEEEIIATCGLLLVAGHETTVNLIANA
: :: . :: . *.: : *:: .* *** . ..
Mflv_4339|M.gilvum_PYR-GCK LYLLLTHRDQFDAVDADHELIGQAIEEGLRYETPLTTVQRFTTEDTELEG
Mvan_2007|M.vanbaalenii_PYR-1 LYLLLTHRDQFEAVNADHALIGAAIEEGLRYETPLTTVQRFANEDTEIDG
MSMEG_2240|M.smegmatis_MC2_155 LYLLLTHPDQFAAVQNDHDLIGAAIEEGLRYETPLTTVQRSATKDTELEG
TH_2944|M.thermoresistible__bu IYLLLTHPEQFAAVAADPGLIPQAIEEGLRHETPLTTVQRLTTEDTELCG
MMAR_4008|M.marinum_M LYLLLAHPDQFMAVRAHRELIPQAIEEGLRFETPLTTVQRFTTKDTEVQG
MUL_3872|M.ulcerans_Agy99 LYLLLAHPDQFMAVRAHRELIPQAIEEGLRFETPLTTVQRFTTKDTEVQG
MAV_1598|M.avium_104 LYLLLTHPDQFAALQADRELLAPAIEEGLRFETPLTTVQRFTTEDTELHG
Mb0789c|M.bovis_AF2122/97 VYWAAHHPGQLARVFADHSRIPMWVEETLRYDTSSQILARTVAHDLTLYD
Rv3518c|M.tuberculosis_H37Rv TEQLLRNRDQWDLLQRDPSLLPGAIEEMLRWTAPVKNMCRVLTADTEFHG
MAB_4456|M.abscessus_ATCC_1997 IAALLRHPQQLAHLRENPDGWPNAVEEILRYDSPVQITGRVATQACEFEG
MLBr_02088|M.leprae_Br4923 VLAMLRNPSQWKALSSNPQRAPLVVEETLRYDPAIHLIGRVAAKDMTIGQ
: * : . :** ** .. * .
Mflv_4339|M.gilvum_PYR-GCK VPIPAGAVIDVCIGSANRDEKRWERSEEFDIFRKR-VPHLSFAAGEHTCM
Mvan_2007|M.vanbaalenii_PYR-1 VEIPAGSVIDVCIGSANRDESRWERAEQFDIFRTR-TPHISFAAGEHTCM
MSMEG_2240|M.smegmatis_MC2_155 VQIPAGAVIDVCIGSANRDENRWERPEEFDIFRKR-IPHITFAAGEHTCM
TH_2944|M.thermoresistible__bu AAIPAGAVVDTCIGSANRDETRWDRPEEFDIFRDR-VPHLSFAAGEHTCM
MMAR_4008|M.marinum_M VPIPARSVIGVCMGSANRDEHRWQRPEVFDIFRER-IPHISFAAGEHTCL
MUL_3872|M.ulcerans_Agy99 VPIPARSVIGVCMGSANRDEHRWQRPEVFDIFRER-IPHISFAAGEHTCL
MAV_1598|M.avium_104 VRIPARSVIGVCIGSANRDERRWERSEEFDIFRKH-VPHISFAAGEHTCL
Mb0789c|M.bovis_AF2122/97 TTIPEGEVLLLLPGSANRDDRVFDDPDDYRIGREIGCKLVSFGSGAHFCL
Rv3518c|M.tuberculosis_H37Rv TALCAGEKMMLLFESANFDEAVFCEPEKFDVQRNP-NSHLAFGFGTHFCL
MAB_4456|M.abscessus_ATCC_1997 HTLAAGSMAILLLGGANRDPAVFDQPDVFDVLRANAREHVAFGSGIHVCL
MLBr_02088|M.leprae_Br4923 TTLTEGDTMVLLLAAANRDPAVYSRPDEFDPDRPS-SRHLAFAVGSHFCL
: .** * : .: : * ::*. * * *:
Mflv_4339|M.gilvum_PYR-GCK GLHLARMETRVAVETLLTRLSDIRLVTDDDPHIHGQP--FRSPTALPVTF
Mvan_2007|M.vanbaalenii_PYR-1 GLHLARMETRVAAETLLSRLSAIELLTDGDPHIHGQP--FRSPTALPVTF
MSMEG_2240|M.smegmatis_MC2_155 GLHLARMETRVAMETLLNRVTDLRLIADDDPHIFGQP--FRSPTAIPVTF
TH_2944|M.thermoresistible__bu GLHLARMETRVALETLLSRVHDLRLVTDGDPHIFGQP--FRSPTAIPVTF
MMAR_4008|M.marinum_M GLHLARLETRVALECLLDRLTNIDLATADDPHIHGQP--FRSPTALPVTF
MUL_3872|M.ulcerans_Agy99 GLHLARLETRVALECLLDRLTNIDLATADDPHIHGQP--FRSPKALPVTF
MAV_1598|M.avium_104 GLHLARLETRVAMECLLNRLTNVTLLSDGDPHIHGQP--FRSPTALPVTF
Mb0789c|M.bovis_AF2122/97 GAHLARMEARVALGALLRRIRNYEVDDDNVVRVHSSN--VRGFAHLPISV
Rv3518c|M.tuberculosis_H37Rv GNQLARLELSLMTERVLRRLPDLRLVADDSVLPLRPANFVSGLESMPVVF
MAB_4456|M.abscessus_ATCC_1997 GASLARMEGVVALQSLFERFPELALAADPTPGKHVNL---HGFGSLPVNL
MLBr_02088|M.leprae_Br4923 GAALARLEATVTLSAISARFPQVQLAGELVYKPNVAM---RGMSALPVQV
* ***:* : : *. : . :*: .
Mflv_4339|M.gilvum_PYR-GCK SPAAAK---
Mvan_2007|M.vanbaalenii_PYR-1 TPSRARP--
MSMEG_2240|M.smegmatis_MC2_155 RPAG-----
TH_2944|M.thermoresistible__bu DPVR-----
MMAR_4008|M.marinum_M EAVPT----
MUL_3872|M.ulcerans_Agy99 EAVPT----
MAV_1598|M.avium_104 DAK------
Mb0789c|M.bovis_AF2122/97 QAR------
Rv3518c|M.tuberculosis_H37Rv TPSPPLG--
MAB_4456|M.abscessus_ATCC_1997 GRARVPASS
MLBr_02088|M.leprae_Br4923 ---------