For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
aa seq not available
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. thermoresistible (build 8) | TH_3493 | - | - | 100% (266) | short-chain dehydrogenase/reductase SDR |
| M. thermoresistible (build 8) | TH_1963 | - | 1e-36 | 45.25% (179) | PROBABLE SHORT-CHAIN TYPE DEHYDROGENASE/REDUCTASE |
| M. thermoresistible (build 8) | TH_3427 | - | 8e-28 | 32.69% (260) | PUTATIVE short-chain dehydrogenase/reductase SDR |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1914c | - | 1e-37 | 44.79% (192) | short chain dehydrogenase |
| M. gilvum PYR-GCK | Mflv_0407 | - | 6e-99 | 66.67% (261) | short chain dehydrogenase |
| M. tuberculosis H37Rv | Rv1882c | - | 1e-37 | 44.79% (192) | short chain dehydrogenase |
| M. leprae Br4923 | MLBr_01094 | - | 5e-24 | 31.93% (238) | short chain alcohol dehydrogenase |
| M. abscessus ATCC 19977 | MAB_3405 | - | 1e-30 | 37.13% (237) | short chain dehydrogenase |
| M. marinum M | MMAR_2770 | - | 6e-38 | 45.26% (190) | short-chain type dehydrogenase/reductase |
| M. avium 104 | MAV_2820 | - | 8e-38 | 41.63% (209) | short chain dehydrogenase |
| M. smegmatis MC2 155 | MSMEG_2477 | - | 6e-25 | 38.46% (195) | cyclopentanol dehydrogenase |
| M. ulcerans Agy99 | MUL_2977 | - | 3e-37 | 44.74% (190) | short chain dehydrogenase |
| M. vanbaalenii PYR-1 | Mvan_0267 | - | 1e-100 | 68.97% (261) | short chain dehydrogenase |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_0407|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_0267|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_3493|M.thermoresistible__bu --------------------------------------------------
Mb1914c|M.bovis_AF2122/97 --------------------------------------------------
Rv1882c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_2770|M.marinum_M --------------------------------------------------
MUL_2977|M.ulcerans_Agy99 --------------------------------------------------
MAV_2820|M.avium_104 --------------------------------------------------
MAB_3405|M.abscessus_ATCC_1997 --------------------------------------------------
MLBr_01094|M.leprae_Br4923 --------------------------------------------------
MSMEG_2477|M.smegmatis_MC2_155 MPTYELLRYHFRSPETAAHFLQTSASHDRRQDRGTETLGISASPSDPTIV
Mflv_0407|M.gilvum_PYR-GCK -------------------------------------------------M
Mvan_0267|M.vanbaalenii_PYR-1 -------------------------------------------------M
TH_3493|M.thermoresistible__bu -----------------------------------------------MRN
Mb1914c|M.bovis_AF2122/97 --------------------------------------------------
Rv1882c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_2770|M.marinum_M --------------------------------------------------
MUL_2977|M.ulcerans_Agy99 --------------------------------------------------
MAV_2820|M.avium_104 --------------------------------------------------
MAB_3405|M.abscessus_ATCC_1997 ---------------------------------------------MDKIT
MLBr_01094|M.leprae_Br4923 ---------------------------------------------MEGFA
MSMEG_2477|M.smegmatis_MC2_155 VEIVCHTDESGARPATDAPGIQRVETLALEPRAAGVSEASRGRSGQGRLA
Mflv_0407|M.gilvum_PYR-GCK TKSVFITGAATGIGRATALLFAGRGYRVGGYDLDEDGLAVLAADITAVGG
Mvan_0267|M.vanbaalenii_PYR-1 TKSVFITGAATGIGRATALLFAQRGYRVGGYDIDEAGLRLLAADITAVGG
TH_3493|M.thermoresistible__bu DKAIFITGAAAGIGRATALTFARKGYTVGAYDIDEAGLGTLAEEIGRLGA
Mb1914c|M.bovis_AF2122/97 MKAIFITGAGSGMGREGATLFHANGWRVGAIDRNEDGLAALRVQLGAE--
Rv1882c|M.tuberculosis_H37Rv MKAIFITGAGSGMGREGATLFHANGWRVGAIDRNEDGLAALRVQLGAE--
MMAR_2770|M.marinum_M MKSVFITGAGSGMGREGAKLFHAKGWRVAAVDRDGAGLDALGAELGTE--
MUL_2977|M.ulcerans_Agy99 MKSGFVTGAGSGMGREGAKLFHAKGWRVAAVDRDGAGLDALGAELGTE--
MAV_2820|M.avium_104 MKSIFITGAGSGMGREGAKLFHAKGWRVGAVDRNDDGLATLQQELGDD--
MAB_3405|M.abscessus_ATCC_1997 GKNIAITGAARGIGYATATALLRRGARVVIGDRDVEALGSAVEGLKEEG-
MLBr_01094|M.leprae_Br4923 GKVAVVTGAGSGIGQALAIELARSGAKLAISDVDGEGLAQTEGQLKAIGA
MSMEG_2477|M.smegmatis_MC2_155 GKVALITGGARGQGEAEARLFAQHGAHVYICDVLEEEGEKLAAELRGSGL
* :**.. * * * : * : * :
Mflv_0407|M.gilvum_PYR-GCK TPVVAHLDVTDPDEVARRLAEFAEG-SGGRIDVLINNAGLLNAGRFEEIP
Mvan_0267|M.vanbaalenii_PYR-1 RPVVGRLDVTDADEVAHRLAEFVDA-AGGRLDVLINNAGLLQAGRFEDIP
TH_3493|M.thermoresistible__bu TVHTGHLDVTDTDEMATRVSEFATQ-AGNRLDVMVNNAGILKAGRFEDID
Mb1914c|M.bovis_AF2122/97 RLWARAVDVTDKAALEGALADFCAGNVGGGLDMMWNNAGIGEGGWFEDVP
Rv1882c|M.tuberculosis_H37Rv RLWARAVDVTDKAALEGALADFCAGNVGGGLDMMWNNAGIGEGGWFEDVP
MMAR_2770|M.marinum_M RLWTRVVDVTDRDALDRALADFCAGTSHGGLDMMWNNAGIGEGGWFEDVP
MUL_2977|M.ulcerans_Agy99 RLWTRVVDVTDRDALDRALADFCAGTSHGGLDMMWNNAGIGEGGWFEDVP
MAV_2820|M.avium_104 RLWTRAVDVTDKAALDGALADFCAGNTGGGLDMMWNNAGIGESGWFEDVP
MAB_3405|M.abscessus_ATCC_1997 NVDAHPLDVTDPASFKRFLEAASAG---GPIDVLVNNAGVMPIGPFLSTS
MLBr_01094|M.leprae_Br4923 SARTDRLDVTEREAFLTYADVVHEN--FGKVNQIYNNAGIAFTGDVEVSH
MSMEG_2477|M.smegmatis_MC2_155 QADFRFLDVTDAEQWSRTVAHIDAG--AGRLDVLINNAGINVRHQLTDTT
:***: . :: : ****: .
Mflv_0407|M.gilvum_PYR-GCK LEVHHREIEVNVKGVVNGLHAAFPYLKGTPGAVVVNLASASAIYGQAELA
Mvan_0267|M.vanbaalenii_PYR-1 LPVHHRAIEVNVKGVVNGLHAAFPYLRDTPDAVVVNLSSASAIYGQVELA
TH_3493|M.thermoresistible__bu VRAHFAEIDVNTKGVVNGLHAAFPHLRATPDSVVVNLASASAIYGQPELA
Mb1914c|M.bovis_AF2122/97 YEAAVRVVDVNFKAVLTGAYAALPYLKKAPGSLMFSTSSSSGTYGMPRIA
Rv1882c|M.tuberculosis_H37Rv YEAAVRVVDVNFKAVLTGAYAALPYLKKAPGSLMFSTSSSSGTYGMPRIA
MMAR_2770|M.marinum_M YDAAMRVVDVNFKAVLTGAYGALPYLRKAPGSLMFSTSSSSATYGMPRLA
MUL_2977|M.ulcerans_Agy99 YDAAMRVVDVNFKAVLTGAYGALPYLRKAPGSLMFSTSSSSATYGMPRLA
MAV_2820|M.avium_104 YDAAMRVVDVNYKAVLTGAYGALPYLKKSAGSLMFSTSSSSATYGMPRLA
MAB_3405|M.abscessus_ATCC_1997 DRAIRSMLEVNLYGVINGCQLALPEMVARRRGQVVNIASVAGLMAVPGMA
MLBr_01094|M.leprae_Br4923 FKDIERVMDVDYWGVVNGTKAFLPYLISSGDGHVINISSVFGLFSVPGQA
MSMEG_2477|M.smegmatis_MC2_155 SEEWDRIVAVNTKGQMLGMQACAPLMKRSGNGSIINIGSTAGIMGHP-VA
: *: . : * * : . :.. .* . . *
Mflv_0407|M.gilvum_PYR-GCK NYSATKFFVRAITEALNLEWGHYG--IRVIDMWPLYVNTAMTKDVKTG--
Mvan_0267|M.vanbaalenii_PYR-1 NYSATKFYVRAITEALNLEWAQHG--IRVIDMWPLYVNTAMTQGVKTG--
TH_3493|M.thermoresistible__bu NYSATKFFVRGLTEALDLEWGRYG--IRVVAIWPLYVQTPMLTGVDTG--
Mb1914c|M.bovis_AF2122/97 VYSATKHAVKGLTEALSVEWQRHG--VRVADVLPGLIDTAILTSTRQHSD
Rv1882c|M.tuberculosis_H37Rv VYSATKHAVKGLTEALSVEWQRHG--VRVADVLPGLIDTAILTSTRQHSD
MMAR_2770|M.marinum_M VYSATKHAVKGLTEALSAEWRRHG--VRVADVLPGLIDTAILTSTRQHSD
MUL_2977|M.ulcerans_Agy99 VYSATKHAVKGLTEALSAEWRRHG--VRVADVLPGLIDTAILTSTRQHSD
MAV_2820|M.avium_104 VYSSTKHAVKGLTEALSVEWQRHG--VRVADVLPGLIDTAILTTTTNHSN
MAB_3405|M.abscessus_ATCC_1997 VYNASKFGVVGLSRALSDEFAPQG--VQVSAVLPTFTNTELIAGTDSTGA
MLBr_01094|M.leprae_Br4923 AYNSAKFAVRGFTEALREEMALAGRPVNVTTVYPGGIKTAIARN------
MSMEG_2477|M.smegmatis_MC2_155 AYSASKWAVRGLTKAAAMELASSG--IRVNAMHPGVVETPMVDAGSR---
*.::* * .::.* * * :.* : * .* :
Mflv_0407|M.gilvum_PYR-GCK ----TTQSLGIRLT-AQD-----IANDIVAAVDATWARKALAQ-VHFPVG
Mvan_0267|M.vanbaalenii_PYR-1 ----TTQSLGIRLT-AQD-----IARDIVTAVEATWPRRLVKQ-VHFPVG
TH_3493|M.thermoresistible__bu ----TTRSLGVRLT-AQD-----VADVIVSAVEPSRLRRTVRQ-VHYPVG
Mb1914c|M.bovis_AF2122/97 EGPYTISAEQIRAA-APKKGMFRLMPSSSVAEAAWRAYQHPTR-LHWYVP
Rv1882c|M.tuberculosis_H37Rv EGPYTISAEQIRAA-APKKGMFRLMPSSSVAEAAWRAYQHPTR-LHWYVP
MMAR_2770|M.marinum_M ASAPTLSSEQIRAA-APKKGMFRLLPASSVAEAAWQAYQHPTR-LHWYVP
MUL_2977|M.ulcerans_Agy99 ASAPTLSSEQIRAA-APKKGMFRLLPASSVAEAAWHAYQHPTR-LHWYVP
MAV_2820|M.avium_104 DGAAPMTAEELRAT-APKKGMLRLMPASSVAEVAWRAYNHPRR-LHWYVP
MAB_3405|M.abscessus_ATCC_1997 QKPVEPEDIAAAVVRIIEKPRVQVTVPKPLGAVTTIVNSLPTG-VRRFMS
MLBr_01094|M.leprae_Br4923 ----ATAAEGLDVSKIASRFDTWVAHTSPQHAARIILKAVRKKKARVLVG
MSMEG_2477|M.smegmatis_MC2_155 ----VFAELRSLTP---------LGRAAQPSEMASAALFLASDEASFITG
:
Mflv_0407|M.gilvum_PYR-GCK LQAKALALGARFSPAWLTRLVNKGLAGS--------
Mvan_0267|M.vanbaalenii_PYR-1 GQAKALALGSRFSPAWLTRLINKRLAGS--------
TH_3493|M.thermoresistible__bu AQTKAFALGSRFSPAWLTRALNKRLAGS--------
Mb1914c|M.bovis_AF2122/97 RSIRWIDRLKGVSPEFVRRHIAKSLATLEPKRK---
Rv1882c|M.tuberculosis_H37Rv RSIRWIDRLKGVSPEFVRRHIAKSLATLEPKRK---
MMAR_2770|M.marinum_M PSVRWIDRLKGVSPEFVRSRILKSLPTFGAGQQ---
MUL_2977|M.ulcerans_Agy99 PSIRWIDRLKGVSPEFVRSRILKSLPTFGTGQQ---
MAV_2820|M.avium_104 RSIRLIDVFKGLSPEFVRRSIVKSLPALMPKRQ---
MAB_3405|M.abscessus_ATCC_1997 KKTGTDRVFLDFDTSARTAYENRAGSSLGVTKPDGE
MLBr_01094|M.leprae_Br4923 PDAKVANVVVRFSGGAGYQRLFAQVASRLILNQR--
MSMEG_2477|M.smegmatis_MC2_155 IDLAVDG---GFSELAAYGEVWKRLNTAL-------
. ..