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M. thermoresistible (build 8) TH_3450 (-)

annotation: MMPL domain protein
coordinates: 4450487 - 4453408
length: 974

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_3450--100% (974)MMPL domain protein
M. thermoresistible (build 8)TH_2203mmpL80.042.02% (978) PROBABLE CONSERVED INTEGRAL MEMBRANE TRANSPORT PROTEIN
M. thermoresistible (build 8)TH_3056-e-12630.02% (976) PUTATIVE Mmp14a protein

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb1215mmpL100.040.95% (972) transmembrane transport protein MmpL10
M. gilvum PYR-GCKMflv_4632-0.083.21% (560) MMPL domain-containing protein
M. tuberculosis H37RvRv1183mmpL100.040.95% (972) transmembrane transport protein MmpL10
M. leprae Br4923MLBr_01231mmpL100.038.69% (977) hypothetical protein MLBr_01231
M. abscessus ATCC 19977MAB_0855-0.039.77% (973) MmpL family protein
M. marinum MMMAR_4836-0.081.51% (968) MmpL family transport protein
M. avium 104MAV_1761-0.039.10% (977) MmpL10 protein
M. smegmatis MC2 155MSMEG_4741-0.040.23% (977) MmpL protein
M. ulcerans Agy99MUL_3688mmpL4_11e-12230.93% (970) transmembrane transport protein MmpL4_1
M. vanbaalenii PYR-1Mvan_0312-0.086.13% (966) MMPL domain-containing protein

CLUSTAL 2.0.9 multiple sequence alignment


TH_3450|M.thermoresistible__bu      ------------------------------------------------VL
MMAR_4836|M.marinum_M               MADYGWVSSGVATLSRPVRERLQKVAAGEGAYSDRLARLAGFSIR-HKVL
Mflv_4632|M.gilvum_PYR-GCK          -MTDGSADAPSQAKRPGRRANGSTDPADTREYSERLATLARFTLR-HKAL
Mvan_0312|M.vanbaalenii_PYR-1       -MTDGTADSPSQATRSGRGANGSPDPADTREYSERLAALARFTLR-HKAL
MAB_0855|M.abscessus_ATCC_1997      ----------------------------MAENTGGIYGLIAQIVRRAPVI
MSMEG_4741|M.smegmatis_MC2_155      ------------------------------MSRVGFSGLGRFIVR-HPLV
Mb1215|M.bovis_AF2122/97            --------------------------------------------------
Rv1183|M.tuberculosis_H37Rv         --------------------------------------------------
MLBr_01231|M.leprae_Br4923          -------------------------------------------------M
MAV_1761|M.avium_104                -----------------------MSPTAPAGDEVEMRRIADFVVR-WPWL
MUL_3688|M.ulcerans_Agy99           --MSESNSGASISTEDTGPIEIGAATGGAPNRERGHRPVIPHTIRILAVP
                                                                                      

TH_3450|M.thermoresistible__bu      VIGTWLAVAVVLALLFPQLETVVRQQSVDLIPRDVPSFQTLDRMSAAFGE
MMAR_4836|M.marinum_M               IIGMWVVTAAALAVLFPQLETVVRQQSVNLIPRDAPSLQTVDRMGAAFGE
Mflv_4632|M.gilvum_PYR-GCK          VIGVWLGAAVVLALLFPQLETVVRQQSVDLIPRDAPSLQTVDRMSAAFGE
Mvan_0312|M.vanbaalenii_PYR-1       VIGVWLGAAVVLALLFPQLETVVRQQSVDLIPRDAPSLQTVDRMSAAFGE
MAB_0855|M.abscessus_ATCC_1997      VIGLWIGLAAVLALTAPSLQKAIEDHPVDLLPKDAPVMETTRQMVESFQE
MSMEG_4741|M.smegmatis_MC2_155      VIASWLAVAGVLLAAVPSLPAVAERNPPGFLPADSEVFAAGNAMQEAFNE
Mb1215|M.bovis_AF2122/97            MVGCWVALALVLPMAVPSLAEMAQRHPVAVLPADAPSSVAVRQMAEAFHE
Rv1183|M.tuberculosis_H37Rv         MVGCWVALALVLPMAVPSLAEMAQRHPVAVLPADAPSSVAVRQMAEAFHE
MLBr_01231|M.leprae_Br4923          VIGCWTLLALMLPMTVPSLTELTQRHPVVILPVDAPSSVAAKKISQAFHE
MAV_1761|M.avium_104                VIGFWAALAVALPLAFPSLAEMAQKHPLAILPGNAPSNVAARQMTEAFHE
MUL_3688|M.ulcerans_Agy99           IILGWVLLTVLVNVVVPSLEVVSEQHSAPMTPMDAPSMKAMMRLGHNFRE
                                    ::  *   :  :    *.*    . :.  . * :     :   :   * *

TH_3450|M.thermoresistible__bu      QGSKTTVFVAMEDPAGLTPAARDRYEAMVSRLRADTDHVLLVQDLLADPV
MMAR_4836|M.marinum_M               QGSKTTIFVAMEDPAGLTAPVRQRYNTMISRLRADSEHVRLVQDLLADPV
Mflv_4632|M.gilvum_PYR-GCK          EGSKTMVFVAMEDPTGLTPTARQRYGELVRRLQAEGDHVLLVQDLLADPI
Mvan_0312|M.vanbaalenii_PYR-1       EGSKTMVFVAMEDPNGLTPTARQRYGELVSRLQSEGDHVLLVQDLLADPI
MAB_0855|M.abscessus_ATCC_1997      SGAQNILLIVLTNENGLTPADEQTYRILAARMREDTRDVSMVQDFITKPP
MSMEG_4741|M.smegmatis_MC2_155      TGGGNVAIAILSNENGLTPADEETYRALVDKLRADTEYVLSTQDFVTIPE
Mb1215|M.bovis_AF2122/97            SGSENILVVLLTDEKGLGAADENVYHTLVDRLRNDAKDVVMLQDFLTTPP
Rv1183|M.tuberculosis_H37Rv         SGSENILVVLLTDEKGLGAADENVYHTLVDRLRNDAKDVVMLQDFLTTPP
MLBr_01231|M.leprae_Br4923          VDSENVLIVLLTDDKGLGPADETVYRTLVDRLRNDTKDVVVLQDFLSTPP
MAV_1761|M.avium_104                SGSDDLLLVALTDEKGLGPADEAVYRRLVDALRRDTRDVVMVQDFISAPP
MUL_3688|M.ulcerans_Agy99           FDSNSTVMIVLEGQHKLGDDAHQYYDSLIRQLRQDPEHIQHIQDFWGDRL
                                     ..    .  : .   *    .  *  :   :: :   :   **:     

TH_3450|M.thermoresistible__bu      TATQAVSQDGKAWYLPVGVAGTLGDPTAAESVQAVRALAAE-------AF
MMAR_4836|M.marinum_M               TASQAVSQDGKAWYVPVGVAGTLGDVKAAESVQAVRTIAAQ-------AF
Mflv_4632|M.gilvum_PYR-GCK          TEAQAVSADRKAWYLPVGVTGTLGDPTAAESLNAVRDIAAE-------VF
Mvan_0312|M.vanbaalenii_PYR-1       TEAQAVSVDRKAWYLPVGVAGTLGDPTAAESVNAVRDIAAE-------VF
MAB_0855|M.abscessus_ATCC_1997      LREMMSSTDGKAWYLPVGLQGELATPESGKAYVGALKIIKD-------AT
MSMEG_4741|M.smegmatis_MC2_155      LRQVMTSEDNKAWQLPISAAGTMGTAEGQNAYRQIVDTVKS-------ST
Mb1215|M.bovis_AF2122/97            LREVLGSKDGKAWILPIGLAGDLGTPKSYHAYTDVERIVKR-------TV
Rv1183|M.tuberculosis_H37Rv         LREVLGSKDGKAWILPIGLAGDLGTPKSYHAYTDVERIVKR-------TV
MLBr_01231|M.leprae_Br4923          LHELLVSKDGKAWILPIVLAGELGTSASYQAYAGVAGIVKQTLE----ST
MAV_1761|M.avium_104                LRSAVTSKDRKAWVLPVGIAGELGTPQSYAAFNRIAGIVKQTLEKHENGP
MUL_3688|M.ulcerans_Agy99           TAAGAQSADGKSAYVMVNLAGNQGTTLANESVEAVRDVINR-------TH
                                          * * *:  : :   *  .   .  :                   

TH_3450|M.thermoresistible__bu      ADSSTTVRVTGPPATFSDQIGSAEHDLVLISIATAGLIALILLIVYRSVF
MMAR_4836|M.marinum_M               SGSPTNVRVTGPPATFHDQIASAEEDLVVISIATAGLIAMILLVVYRSVF
Mflv_4632|M.gilvum_PYR-GCK          TGSTTTVQVTGPPATFSDMIASAEHDLLLISIATAGVIALILLIVYRSVF
Mvan_0312|M.vanbaalenii_PYR-1       TGSTTTVHVTGPPATFSDMIASAEHDLLLISIATAGVIALILLIVYRSVF
MAB_0855|M.abscessus_ATCC_1997      QGTSLKAFTTGPTATVGDLTVVGERDLHKVEITTAALVLLILLIVYRNPV
MSMEG_4741|M.smegmatis_MC2_155      ANTSLSAEVIGPAATFEDVVKIGERDQHVIEIATVLIVLMILIIVYRNLV
Mb1215|M.bovis_AF2122/97            AGTTLTANVTGPAATVADLTDAGARDRASIELAIAVMLLVILMVIYRNPV
Rv1183|M.tuberculosis_H37Rv         AGTTLTANVTGPAATVADLTDAGARDRASIELAIAVMLLVILMVIYRNPV
MLBr_01231|M.leprae_Br4923          AGSSLKANLTGPASTVADLTDAGARDRTSIELVIAVLLLTILMIIYRNPI
MAV_1761|M.avium_104                AATSLTVSLTGPAATVADLTVAGERDRLPIELAIAVLVLVVLLVVYRSAV
MUL_3688|M.ulcerans_Agy99           EPAGVKAYVTGPAALSDDMHLIGNASLATITMFTLGAIAVMLLLVYRSIV
                                      :  ..   **.:   *    .  .   : :     :  :*:::**. .

TH_3450|M.thermoresistible__bu      TALLPLLVIGVSLAVGRGVLSALGEMGMP-VSQFTVAFMTAILLGAGTDY
MMAR_4836|M.marinum_M               TALLPLLVIGVSLAVGRGVLSALGESGMP-VSQFTIAFMTVILLGAGTDY
Mflv_4632|M.gilvum_PYR-GCK          TALLPLLVIGLSLAVGRGVLSALGEMGMP-VSQFTVAFMTAILLGAGTDY
Mvan_0312|M.vanbaalenii_PYR-1       TALLPLLVIGLSLAVGRGVLSALGEMGMP-VSQFTVAFMTAILLGAGTDY
MAB_0855|M.abscessus_ATCC_1997      TMMLPLIVVGVSLGIAQAAVGGLAQMGLS-ISNQTLTFMTAMMMGAGVDY
MSMEG_4741|M.smegmatis_MC2_155      AMLLPLLMIGMALVVAEQSVAGLGAIHLIGLGPQTLMLMTAMMMGAGTDY
Mb1215|M.bovis_AF2122/97            TMLLPLVTIGASLMTAQALVAGVSLVGGLAVSNQAIVLLSAMIAGAGTDY
Rv1183|M.tuberculosis_H37Rv         TMLLPLVTIGASLMTAQALVAGVSLVGGLAVSNQAIVLLSAMIAGAGTDY
MLBr_01231|M.leprae_Br4923          TMLLPLITIGASLMTAQAVVSGVSVLAGLAVSNQMIVLLSAMIAGAGTDY
MAV_1761|M.avium_104                TMLLPLVTILLSLVIAQAAVAGYSQLTGSGVSNQSIVFLSAIMAGAGTDY
MUL_3688|M.ulcerans_Agy99           TTVIQLFMTGIALASSRGVVAVLGYHNVFGLTTFAANILTMLAIAAGTDY
                                    : :: *.    :*  ..  :.  .      :      ::: :  .**.**

TH_3450|M.thermoresistible__bu      TVFLISRYHEQRRAQ----VAPEQAAIYATASIGRVILASAATVAFAFLA
MMAR_4836|M.marinum_M               SVFLISRYHEQRRQN----VPPDLSVINATATIGRVILASAATVAFAFLA
Mflv_4632|M.gilvum_PYR-GCK          TVFLISRYHEQRRAQ----VPADQAIIHATASIGRVILASAATVALAFLA
Mvan_0312|M.vanbaalenii_PYR-1       TVFLISRYHEQRRAQ----VPADQAIIHATASIGRVILASAATVALAFLA
MAB_0855|M.abscessus_ATCC_1997      AVFLISRYHEYIKQG----LASDDAVAAALESIGKVVAASAATVAVTFLG
MSMEG_4741|M.smegmatis_MC2_155      AIFLFSRYHECVRSG----LSSDDAVVEALDSIGKVIAGSAGTVAITFMG
Mb1215|M.bovis_AF2122/97            AVFLISRYHEYVRLG----EHPERAVQRAMMSVGKVIAASAATVGITFLG
Rv1183|M.tuberculosis_H37Rv         AVFLISRYHEYVRLG----EHPERAVQRAMMSVGKVIAASAATVGITFLG
MLBr_01231|M.leprae_Br4923          AVFLISRYHDYIRMGSGSAQDAGCAVRQALISLGKVIAASAATVGITFLG
MAV_1761|M.avium_104                AVFLISRYHDFLRRG----DDFDQAVRKALISIGKVITASASTVGITFLL
MUL_3688|M.ulcerans_Agy99           GIFLVGRYQEARQAG----EDRQDAYYTTFRGVAPVVLGSGLTIAGATYC
                                     :**..**::  :           :   :   :. *: .*. *:. :   

TH_3450|M.thermoresistible__bu      MVFARLSVFAALGPACAIAVLFGFLATVTLLPPVLALAAKRG-IGDPKPD
MMAR_4836|M.marinum_M               MVFAKLSVFAALGPACAIAVFVGFAATVTLFPPVLALAAKRG-IGEPKAD
Mflv_4632|M.gilvum_PYR-GCK          MVFARLSVFAALGPACAIAVLFGFLATVTLLPPVLSLAAKRG-IGEPKPD
Mvan_0312|M.vanbaalenii_PYR-1       MVFARLSVFAALGPACAIAVLFGFLATVTLLPPVLSLAAERG-IGEPKSD
MAB_0855|M.abscessus_ATCC_1997      MGFTKLGILSTVGPALSVSILIAFVASVTFLPAVLVLVGRRG-WITPRKA
MSMEG_4741|M.smegmatis_MC2_155      LAFTDLGVFSTVGPALSVTIGFGFVASVTLLPAMVVLAGRRG-WVKPRKD
Mb1215|M.bovis_AF2122/97            MRFAKLGVFSTVGPALAIGIAVSFLAAVTLLPAILVLASPRG-WVAPRGE
Rv1183|M.tuberculosis_H37Rv         MRFAKLGVFSTVGPALAIGIAVSFLAAVTLLPAILVLASPRG-WVAPRGE
MLBr_01231|M.leprae_Br4923          MSFTKIRVFSTVGPALAIGIAVAFLAAVTLMPALLVLAGTRG-WVAPRRD
MAV_1761|M.avium_104                IGFARMGVFKTVGISSAIGIGVAFLAAVTLLPAIMVLAGPRG-WIRPRRE
MUL_3688|M.ulcerans_Agy99           LSFARLPWFNTMGAPVAIGMLVVVLAGLTLGPAVVFVGSRFHPFESKRAA
                                    : *: :  : ::* . :: : . . * :*: *.:: : .        :  

TH_3450|M.thermoresistible__bu      RTRRYWNSVAVAVVRRPVTLLTISLAVLLALSAVAVTINISYDDRKGQPA
MMAR_4836|M.marinum_M               RTRRYWNWIAVAVVRRPVPLLVASLALVLGLAAVALTMHISYDDRRGQPA
Mflv_4632|M.gilvum_PYR-GCK          RTRRYWNSVAVAVVRRPVPLLIVSLVILLALSAAAATIKISYDDRKGQPD
Mvan_0312|M.vanbaalenii_PYR-1       RTRRYWNSVAVAVVRRPVPLLIVSLVILLALSAAAATIKISYDDRKGQPA
MAB_0855|M.abscessus_ATCC_1997      YANKIWHRSGINIVKRPGAHLAVSLVVLVILATCGAMVKFGYDDRKNLPP
MSMEG_4741|M.smegmatis_MC2_155      LTGRIWRRSGVHIVRKPVIHLVASLTVLLALAGCAMLVNFNYDDRKNLPD
Mb1215|M.bovis_AF2122/97            RMATFWRRAGTRIVRRPKAYLGASLIGLVALASCASLAHFNYDDRKQLPP
Rv1183|M.tuberculosis_H37Rv         RMATFWRRAGTRIVRRPKAYLGASLIGLVALASCASLAHFNYDDRKQLPP
MLBr_01231|M.leprae_Br4923          RAGAFWRRTGVRIVRRPVAYLSASMVILIVLALCASLVRFNYDDRKQIPA
MAV_1761|M.avium_104                LTTGLWRRSGIRIVRRPRAHLVASVLVLIILASCAGLVRYNYDDRKALRP
MUL_3688|M.ulcerans_Agy99           NRGRLWRRVGTAVVRWPAPILALSGAIVLVGMVALPGFKTSYNDRYYLPA
                                         *.  .  :*: *   *  *   ::         . .*:**     

TH_3450|M.thermoresistible__bu      DTASNQGYQLLDRHFRKDVVFTEFLVVENPTDMRTGKGLADLDEMASRVA
MMAR_4836|M.marinum_M               TTASNEGYRLLDRHFRKDAIVTEFMVVESPTDMRTSKALADLDEMASRVS
Mflv_4632|M.gilvum_PYR-GCK          TTASNQGYHLLDRHFRKDVVISEFLVVENPTDMRTGKGLADLDEMASRVS
Mvan_0312|M.vanbaalenii_PYR-1       TTASNQGYHLLDRHFRKDVVITEFLVVENPTDMRTGKGLADLDEMASRVS
MAB_0855|M.abscessus_ATCC_1997      WADSNQGYAAIEKHFPVNSTLPQYLYIKSPHDLRTPRGLADLEQMAARVS
MSMEG_4741|M.smegmatis_MC2_155      DAHSNMGYAALDKHFPVSSTVQQFILIQSPHDLRSPKALADMEQMAQRVS
Mb1215|M.bovis_AF2122/97            SDPSSVGYAAMEHHFSVNQTIPEYLIIHSAHDLRTPRGLADLEQLAQRVS
Rv1183|M.tuberculosis_H37Rv         SDPSSVGYAAMEHHFSVNQTIPEYLIIHSAHDLRTPRGLADLEQLAQRVS
MLBr_01231|M.leprae_Br4923          SDESSVGYAALESHFPVGQAIPEYLLIQSPHDLRTPRALADMAELAQRVS
MAV_1761|M.avium_104                SAPSSVGYAALERHFPVNQSIPEYILIRSPHDLRTPQALADLEQLADRVS
MUL_3688|M.ulcerans_Agy99           SAPSNLGEAAADRHFSHARMNPDMLMVEAEHDMRNPADMLVLDKVAKNVI
                                       *. *    : **       : : :.   *:*.   :  : ::* .* 

TH_3450|M.thermoresistible__bu      QIPGVTKVSGVTRPTGERLDQAKLAWQNQQIGDKMADAVADGNARKADLA
MMAR_4836|M.marinum_M               QLPGVTKVSGVTRPTGARLDQAQLSWQNGEIGDKMAGAVAKGDAHKDDLA
Mflv_4632|M.gilvum_PYR-GCK          QIPGVTKVSGVTRPTGERLDQAELAWQNGQIGDKMAGAVAEGNSRKDDLA
Mvan_0312|M.vanbaalenii_PYR-1       QIPGVTKVSGVTRPTGERLDQAELAWQNGQIGDKMAGAVAEGNSRKDDLA
MAB_0855|M.abscessus_ATCC_1997      QVPGVDKVRGITRPTGEPLEEAKLSYQAGEVGGKLGDASNLIDARTRDLD
MSMEG_4741|M.smegmatis_MC2_155      QLPDIEMVRGVTRPTGEMLQEARATWQAGEVGGKLNDASTLIDANDANLS
Mb1215|M.bovis_AF2122/97            QIPGVAMVRGVTRPNGETLEQARATYQAGQVGNRLGGASRMIDERTGDLN
Rv1183|M.tuberculosis_H37Rv         QIPGVAMVRGVTRPNGETLEQARATYQAGQVGNRLGGASRMIDERTGDLN
MLBr_01231|M.leprae_Br4923          QIPGIALVRGVTRPTGKPLEETSATYQAGMVGKQLGSASHLIGESTGDLN
MAV_1761|M.avium_104                QLPNVSVVSGITRPTGNVPEQFRATYQAGAIGSMLAGGSTMINDQTDDLN
MUL_3688|M.ulcerans_Agy99           RTVGIAMIQDITRPLGIPIQHSSIPFQNSMQSQTMMQNMAFLKERMADMT
                                    :  .:  : .:*** *   :.   .:*    .  :            :: 

TH_3450|M.thermoresistible__bu      KLTNGADQLAAGLAQLDTTLRTALAPLSGILSQAQSAGTQMQQFRPLLQQ
MMAR_4836|M.marinum_M               KLTHGADQLAGGLAQLDTTLRTALTPLTGLLTQAQSSGSQVQRFRPLLQQ
Mflv_4632|M.gilvum_PYR-GCK          KLTGGADQLADGLAQLDSTVRTALTPLAGILTQAQSAGTQVNQFRPGLLR
Mvan_0312|M.vanbaalenii_PYR-1       KLTGGADQLADGLAQLDSTVRTALTPLAEILTQAQSAGTQVNQFRPLLQQ
MAB_0855|M.abscessus_ATCC_1997      KLAAGGHTLADKLGQVRDSVKNSLGTARALVEVLAQLRGS-GRTGT-LAD
MSMEG_4741|M.smegmatis_MC2_155      TLSGGAHKLADVLGQISTQVTNALVTVRPLAGALADMETKYGGEKT-LDQ
Mb1215|M.bovis_AF2122/97            RLASGANLLADNLGDVRGQVSRAVAGVRSLVDALAYIQNQFGGNKT-FNE
Rv1183|M.tuberculosis_H37Rv         RLASGANLLADNLGDVRGQVSRAVAGVRSLVDALAYIQNQFGGNKT-FNE
MLBr_01231|M.leprae_Br4923          RLASGAGLLADKLGDVRIQVGQAVAGISGLLDNLAFAQKMFGDSKT-LGE
MAV_1761|M.avium_104                RLARGAGTLADNLGDVRGQVNQLAASVRELENAFSSTKNQYSGDAL-VNQ
MUL_3688|M.ulcerans_Agy99           KMADEMQVLIDTTERMYAVMRELDTTTTDMARVTAETSTITDELRDHLAE
                                     ::     *      :   :         :                 .  

TH_3450|M.thermoresistible__bu      LSATAPAVDQAIQAGPGLRPWADQAAHAIAILDPLVGALNTAPWCATTPQ
MMAR_4836|M.marinum_M               LSATAPAVDQAIRTGPGLRQQADQAQNAIAAIDPLVGALNTSPWCATTPE
Mflv_4632|M.gilvum_PYR-GCK          AFRTADFAGIMPR------------------------AVNSCIRCGLHAA
Mvan_0312|M.vanbaalenii_PYR-1       LSATAPAVDQAIQSSPGLRPLANQAQNAISQLDPLVGALNTSPWCATTPQ
MAB_0855|M.abscessus_ATCC_1997      LDSVDKLVTSMHSLGDAIEANAQGASEVYGWIEPVARVLVGNPACDMDPG
MSMEG_4741|M.smegmatis_MC2_155      IDQSAELVANMRSLGRAMGVNLARITDVYDWSAPMVRALNVSPECNLDPA
Mb1215|M.bovis_AF2122/97            IDNAARLVSNIHALGDALQVNFDGIANSFDWLDSVVAALDTSPVCDSNPM
Rv1183|M.tuberculosis_H37Rv         IDNAARLVSNIHALGDALQVNFDGIANSFDWLDSVVAALDTSPVCDSNPM
MLBr_01231|M.leprae_Br4923          IDTAGKLVSSMRALGNMFGINFSTTMNDINWVGAVVIALDSSVLCDTNPI
MAV_1761|M.avium_104                VDIAARLVDHVNSLSNAMGWNFTAAKNMFAWIGPVLAALQGNPVCDADSS
MUL_3688|M.ulcerans_Agy99           FDDFWRPMR---------------------------SYFYWEKHCFDVPI
                                                                          .     *   . 

TH_3450|M.thermoresistible__bu      CAQIRDQVQVLVTLRNSGFFNQVADLGDRYNPATG-ATVAETLADIRNAV
MMAR_4836|M.marinum_M               CTQLRDQVQILVTLRHTGFFNQLANLGDLYQPGS--DTAAGTVADVQNTI
Mflv_4632|M.gilvum_PYR-GCK          CG-----------------------------SPTR-SEVCADYRTVR---
Mvan_0312|M.vanbaalenii_PYR-1       CAQIRDQVKILVTLRDSGFFTQIADLGDRYDPATN-ATVGGTLANVQNAV
MAB_0855|M.abscessus_ATCC_1997      CRSSRDEMNKFLETKQDGTRDKIVELGRELKSVDNDKQISSTIARLRTAL
MSMEG_4741|M.smegmatis_MC2_155      CAASRSDLQRIVEAKDNGNLDKFAELGRQLESTEGDETLDEAVSGLQQSI
Mb1215|M.bovis_AF2122/97            CGNARVQFHKLQTARDNGTLDKVVGLARQLQSTRSPQTVSAVVNDLGRSL
Rv1183|M.tuberculosis_H37Rv         CGNARVQFHKLQTARDNGTLDKVVGLARQLQSTRSPQTVSAVVNDLGRSL
MLBr_01231|M.leprae_Br4923          CADARAQFHKLLTASEDGTLDNIAHLWKQLGSTQSSQTIGATVSGLEKTL
MAV_1761|M.avium_104                CSATRATFEQLVGPRGQADLDAIDDLSHQLQAYPDKRALKASTDRLRNAF
MUL_3688|M.ulcerans_Agy99           CWSFRS----------------------LFDSLDGIDKLSEKFSELTEDI
                                    *                              .             :    

TH_3450|M.thermoresistible__bu      TAMDKAFGAL--GDPADLAGNIGRLQDGISQLASGAQALATGVHTLVDSN
MMAR_4836|M.marinum_M               TSLDKTFGAL--GDPADLAGNIRRLQSGISQLASGAQALATGVHTLADSN
Mflv_4632|M.gilvum_PYR-GCK          -----------------YSGQYQLLLSSASDTPCGAHVHFSGLQRMILR-
Mvan_0312|M.vanbaalenii_PYR-1       ASLDKAFGAL--GDPADLATNLRRLQDGIGQLASGAQALATGVRTLADSN
MAB_0855|M.abscessus_ATCC_1997      NSIDTNLRRLGLSDSYGIQKRFTEVLTGVNSLADGSAQLAEGVQMLVDQT
MSMEG_4741|M.smegmatis_MC2_155      KEATAAARELGLEDASSVKRQLDQLEQGVNLLADSSHQLAQGVQLLVDQT
Mb1215|M.bovis_AF2122/97            NSVVRSLKSLGLDNPDAARARLISMQNGANDLASAGRQVADGVQMLVDQT
Rv1183|M.tuberculosis_H37Rv         NSVVRSLKSLGLDNPDAARARLISMQNGANDLASAGRQVADGVQMLVDQT
MLBr_01231|M.leprae_Br4923          TAVNTSLRSLGLDNPNVMRSKMIGLQNGVNDLASAGRRIADGVAVLVDQT
MAV_1761|M.avium_104                AKLNDVLRAMGMDRPGGLQSNLTTLQNGADQFAGGSRQVADAVAQLVDKV
MUL_3688|M.ulcerans_Agy99           QR---------------TAGLTSQMLTLIPPMIATMKTTKALTLTMQSTF
                                                            :                    :    

TH_3450|M.thermoresistible__bu      LEMLSGMSQIATQLQNSARASADSDSSSGFYLPPNTFENRQFADVAKQFL
MMAR_4836|M.marinum_M               IEMLSGMSQIATQLQNSARTTAGSDNASGFYLPTNAFENRQFADVAKHFL
Mflv_4632|M.gilvum_PYR-GCK          -----------ARYPNIFRSAPARLS----------YQGRRF--------
Mvan_0312|M.vanbaalenii_PYR-1       IEMLSGMSQIATQLQNSSRAAADSDSSSGFYLPANAFENRQFTDVAEQFL
MAB_0855|M.abscessus_ATCC_1997      KQMGGQLGDASTLLVAAKRDAA-PGSMSGFYIPQQVLTQDSFKTAAAAFV
MSMEG_4741|M.smegmatis_MC2_155      RNMGQGLDQASQFLLAMKRDAS-DPQMSGFYIPPQILTQEEFNKAAALFV
Mb1215|M.bovis_AF2122/97            KNMGIGLNQASAFLMAMGNDAS-QPSMAGFNVPPQVLKSEEFKKVAQAFI
Rv1183|M.tuberculosis_H37Rv         KNMGIGLNQASAFLMAMGNDAS-QPSMAGFNVPPQVLKSEEFKKVAQAFI
MLBr_01231|M.leprae_Br4923          RTMGTSLARASAFLMEMGQDAS-QPSMAGFNVPPQLLNTEDFKKLVQAFI
MAV_1761|M.avium_104                KQLGAGLSESAAFLLSLKHDAA-HPAMAGFNIPAQLLRLPQFQEAAKVFI
MUL_3688|M.ulcerans_Agy99           SAMLDQMDELSNTAIVMGQSFDASKNDDFFYLPPEAFDNPDFQTGLRMFL
                                                      .                      *        

TH_3450|M.thermoresistible__bu      SPDGKTARFAIESSHDPYSVDAMNLAHTITDVADAARPNTSLAHATVSVA
MMAR_4836|M.marinum_M               SPDGKTARFAIESSYDPYSSDAMNLAHKITEVADAARPNTSLANATVSMA
Mflv_4632|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_0312|M.vanbaalenii_PYR-1       SPDGKTARFMIESSHDPYSVEAMDLASRITDTANTARPNTSLADATVSVA
MAB_0855|M.abscessus_ATCC_1997      SADGHAVRYLVQSNLNPFSPEAMDQVRAIQEAARSAQPNTTLSDASISMA
MSMEG_4741|M.smegmatis_MC2_155      SPDGRSVRYLVQTALDPFGTAAMDQVKDIVKTAESARPNTSLTDAKISLV
Mb1215|M.bovis_AF2122/97            SPDGHTVRYFIQTDLNPFSTAAMDQVNTIIDTAKGAQPNTSLADASISMS
Rv1183|M.tuberculosis_H37Rv         SPDGHTVRYFIQTDLNPFSTAAMDQVNTIIDTAKGAQPNTSLADASISMS
MLBr_01231|M.leprae_Br4923          SPDGHSVRYFIQTDLNPFSSAAMDQVNTILNVATGAQPNTTLSDASIYLS
MAV_1761|M.avium_104                SPDGHSVRYLVQSKLSPFSTQAMDQVDAITATARGAQPNTALADAEVSMA
MUL_3688|M.ulcerans_Agy99           SPDGKSARFFITHQGDPMTPEGISRVDAERTAAQEGLKQSSLSDAKVYLG
                                                                                      

TH_3450|M.thermoresistible__bu      GFPAVNSDIARLLWADFAQLAIATIVIVGLILVLLLRALLAPIYLLGTVV
MMAR_4836|M.marinum_M               GFPAVNSDIQRLLSADFHQLAFATLVIVGLILVVLLRALVAPLYLLGTVV
Mflv_4632|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_0312|M.vanbaalenii_PYR-1       GFPAVNSDIQRLLWADFAQLAIATIIIVGVILVLLLRALLAPLYLLGTVV
MAB_0855|M.abscessus_ATCC_1997      GLSAMYNDIRNYYNHDLRFIIVLTVIVVLLILVALLRAIVAPLYLIGSVI
MSMEG_4741|M.smegmatis_MC2_155      GFSSIQNEMRNYYDGDLRFIITVTLIVVFLILAALLRSIIAPIYLVLSVV
Mb1215|M.bovis_AF2122/97            GYPVMLRDIRDYYERDMRLIVAVTVVVVILILMALLRAIVAPLYLVGSVV
Rv1183|M.tuberculosis_H37Rv         GYPVMLRDIRDYYERDMRLIVAVTVVVVILILMALLRAIVAPLYLVGSVV
MLBr_01231|M.leprae_Br4923          GYTVTLRDTRDYYDRDLQLIVIVTMIVVLLILMALLRSIVAPIYLVGSVI
MAV_1761|M.avium_104                GYTVGLKDTRDYYQHDIKFIIAVTLLVVLLTLMALLRAIVAPLYLVATVV
MUL_3688|M.ulcerans_Agy99           GTAATFKDMADGEKYDLMIAVVSALTLIFLIMLLLTRSVVAALVIVGTAA
                                                                                      

TH_3450|M.thermoresistible__bu      LNYLASLGIGVLVFQYLLGHEIAWPVPLLAFIILVAVGADYNMLLVSRLR
MMAR_4836|M.marinum_M               LNYGAALGLGTLVFQYGLGKEIAWPVPLLAFIILVAVGADYNMLLISRLR
Mflv_4632|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_0312|M.vanbaalenii_PYR-1       LNYLASLGIGVVVFQWGLGHEIAWPVPLLAFIILVAVGADYNMLLVSRLR
MAB_0855|M.abscessus_ATCC_1997      ISYASAVGIGVIAFQFIGGQPLSWSVPGMAFIVLVAVGADYNLLFISRIR
MSMEG_4741|M.smegmatis_MC2_155      LSYMSALGIGVVFFQFILGKEIVWTVPGMAFLVLVAVGADYNLLLISRIR
Mb1215|M.bovis_AF2122/97            ISYMSAIGLGVVVFQVFLGQELHWSVPGLAFVVLVAVGADYNMLLASRLR
Rv1183|M.tuberculosis_H37Rv         ISYMSAIGLGVVVFQVFLGQELHWSVPGLAFVVLVAVGADYNMLLASRLR
MLBr_01231|M.leprae_Br4923          VSYLSALGLCVLVFQVLLRQQLHWSVPGLAFVVLVAVGADYNMLLASRLR
MAV_1761|M.avium_104                ISYLSAVGVGVLVFQFLLGQQLHWSVPPLAFVVLVAVGADYNMLLVSRMR
MUL_3688|M.ulcerans_Agy99           SSIAASFGLSVLIWQDLFGIKIHWIVAALSVIILLAVGSDYNLLLVSRFR
                                                                                      

TH_3450|M.thermoresistible__bu      EESGTNIRVGVLRTVANTGSVITSAGVIFAASMFGLMFGSIAIMIQAGFI
MMAR_4836|M.marinum_M               EESAHNIRVGVLRTVANTGSVITSAGLIFAASMFGLIAGSIAIMIQAGFI
Mflv_4632|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_0312|M.vanbaalenii_PYR-1       EESGTNIRVGVLRTVANTGAVITSAGLIFAASMFGLMVGSVAIMIQAGLI
MAB_0855|M.abscessus_ATCC_1997      DESPDGIRSGVIKTVKSTGGVITSAGVIFAASMFGLLIGNLQSMVEAGFI
MSMEG_4741|M.smegmatis_MC2_155      DEAAHGMRTAVIRTIGATGGVITSAGLIFAASMFGLTFSSLLAAVQIGFI
Mb1215|M.bovis_AF2122/97            DESALGVRSSVIRTVRCTGGVITAAGLIFAASMSGLLFSSIGTVVQGGFI
Rv1183|M.tuberculosis_H37Rv         DESALGVRSSVIRTVRCTGGVITAAGLIFAASMSGLLFSSIGTVVQGGFI
MLBr_01231|M.leprae_Br4923          DESSHGLRASVIRTVRSTGGVITAAGLIFAASMFGLLLSSIATVVQAGFV
MAV_1761|M.avium_104                DESPHSMRYGIIRTLSSTGGVITAAGLIFAASMSGLLFSSIGTVVQGGVV
MUL_3688|M.ulcerans_Agy99           EEIHAGLKTGIIRSMAGTGGVVTAAGLVFAFTMASMLGSDLRVLGQFGST
                                                                                      

TH_3450|M.thermoresistible__bu      VGCGLLLDTFLVRTLTVPAIATLLREASWWP--------------QPNRA
MMAR_4836|M.marinum_M               IGCGLLLDTFVVRTLTVPAIATLLREASWWP--------------QRKPL
Mflv_4632|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_0312|M.vanbaalenii_PYR-1       IGFGLLLDTFLVRTLTVPAIATLLREASWWP--------------TKATN
MAB_0855|M.abscessus_ATCC_1997      IGMGLLLDTFLVRTITIPALVVLCGQANWWPSASVESWFRQRFSRSKPDA
MSMEG_4741|M.smegmatis_MC2_155      IGVGLLLDTFLVRTITVPAAAVLIGKLSWWP--------------TKPPA
Mb1215|M.bovis_AF2122/97            IGVGILIDTFVVRTITVPAMATLLGRASWWP--------------GHPWQ
Rv1183|M.tuberculosis_H37Rv         IGVGILIDTFVVRTITVPAMATLLGRASWWP--------------GHPWQ
MLBr_01231|M.leprae_Br4923          LGSGILLDTFIVRTITVPAVAALLRRASWWP--------------ARPWG
MAV_1761|M.avium_104                IGVGILLDTFLVRTVTVPAIAALAGRANWWP--------------SRIAV
MUL_3688|M.ulcerans_Agy99           VCIGLLLDTLIVRTLLMPSIATLLGRWFWWP------------QVVHPRG
                                                                                      

TH_3450|M.thermoresistible__bu      R------------------------------------
MMAR_4836|M.marinum_M               THNG---------------------------------
Mflv_4632|M.gilvum_PYR-GCK          -------------------------------------
Mvan_0312|M.vanbaalenii_PYR-1       PRRGDPKQKA---------------------------
MAB_0855|M.abscessus_ATCC_1997      QEGDCAVSDDPEAASGESSPEEPLISASREVELAGRR
MSMEG_4741|M.smegmatis_MC2_155      P---------------EPAPTEPTVAPAAQA------
Mb1215|M.bovis_AF2122/97            RCAPEEGQMSARMSARTKTVFQAVADGSKR-------
Rv1183|M.tuberculosis_H37Rv         RCAPEEGQMSARMSARTKTVFQAVADGSKR-------
MLBr_01231|M.leprae_Br4923          NNA----------------------------------
MAV_1761|M.avium_104                RRNPVSGQP----------------------------
MUL_3688|M.ulcerans_Agy99           DNARPRVAAPTH-------------------------