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TDGTADSPSQATRSGRGANGSPDPADTREYSERLAALARFTLRHKALVIGVWLGAAVVLALLFPQLETVV RQQSVDLIPRDAPSLQTVDRMSAAFGEEGSKTMVFVAMEDPNGLTPTARQRYGELVSRLQSEGDHVLLVQ DLLADPITEAQAVSVDRKAWYLPVGVAGTLGDPTAAESVNAVRDIAAEVFTGSTTTVHVTGPPATFSDMI ASAEHDLLLISIATAGVIALILLIVYRSVFTALLPLLVIGLSLAVGRGVLSALGEMGMPVSQFTVAFMTA ILLGAGTDYTVFLISRYHEQRRAQVPADQAIIHATASIGRVILASAATVALAFLAMVFARLSVFAALGPA CAIAVLFGFLATVTLLPPVLSLAAERGIGEPKSDRTRRYWNSVAVAVVRRPVPLLIVSLVILLALSAAAA TIKISYDDRKGQPATTASNQGYHLLDRHFRKDVVITEFLVVENPTDMRTGKGLADLDEMASRVSQIPGVT KVSGVTRPTGERLDQAELAWQNGQIGDKMAGAVAEGNSRKDDLAKLTGGADQLADGLAQLDSTVRTALTP LAEILTQAQSAGTQVNQFRPLLQQLSATAPAVDQAIQSSPGLRPLANQAQNAISQLDPLVGALNTSPWCA TTPQCAQIRDQVKILVTLRDSGFFTQIADLGDRYDPATNATVGGTLANVQNAVASLDKAFGALGDPADLA TNLRRLQDGIGQLASGAQALATGVRTLADSNIEMLSGMSQIATQLQNSSRAAADSDSSSGFYLPANAFEN RQFTDVAEQFLSPDGKTARFMIESSHDPYSVEAMDLASRITDTANTARPNTSLADATVSVAGFPAVNSDI QRLLWADFAQLAIATIIIVGVILVLLLRALLAPLYLLGTVVLNYLASLGIGVVVFQWGLGHEIAWPVPLL AFIILVAVGADYNMLLVSRLREESGTNIRVGVLRTVANTGAVITSAGLIFAASMFGLMVGSVAIMIQAGL IIGFGLLLDTFLVRTLTVPAIATLLREASWWPTKATNPRRGDPKQKA*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_0312 | - | - | 100% (1028) | MMPL domain-containing protein |
| M. vanbaalenii PYR-1 | Mvan_2900 | - | 0.0 | 69.63% (991) | MMPL domain-containing protein |
| M. vanbaalenii PYR-1 | Mvan_0271 | - | 0.0 | 40.12% (992) | transport protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1215 | mmpL10 | 0.0 | 41.15% (977) | transmembrane transport protein MmpL10 |
| M. gilvum PYR-GCK | Mflv_4632 | - | 0.0 | 95.76% (590) | MMPL domain-containing protein |
| M. tuberculosis H37Rv | Rv1183 | mmpL10 | 0.0 | 41.15% (977) | transmembrane transport protein MmpL10 |
| M. leprae Br4923 | MLBr_01231 | mmpL10 | 0.0 | 38.24% (986) | hypothetical protein MLBr_01231 |
| M. abscessus ATCC 19977 | MAB_0855 | - | 0.0 | 40.08% (983) | MmpL family protein |
| M. marinum M | MMAR_4836 | - | 0.0 | 78.78% (985) | MmpL family transport protein |
| M. avium 104 | MAV_1761 | - | 0.0 | 39.92% (1002) | MmpL10 protein |
| M. smegmatis MC2 155 | MSMEG_4741 | - | 0.0 | 39.78% (998) | MmpL protein |
| M. thermoresistible (build 8) | TH_3450 | - | 0.0 | 86.13% (966) | PUTATIVE MMPL domain protein |
| M. ulcerans Agy99 | MUL_3688 | mmpL4_1 | 1e-121 | 30.69% (1007) | transmembrane transport protein MmpL4_1 |
CLUSTAL 2.0.9 multiple sequence alignment
Mvan_0312|M.vanbaalenii_PYR-1 -MTDGTADSPSQATRSGRGANGSPDPADTREYSERLAALARFTLR-HKAL
Mflv_4632|M.gilvum_PYR-GCK -MTDGSADAPSQAKRPGRRANGSTDPADTREYSERLATLARFTLR-HKAL
MMAR_4836|M.marinum_M MADYGWVSSGVATLSRPVRERLQKVAAGEGAYSDRLARLAGFSIR-HKVL
TH_3450|M.thermoresistible__bu ------------------------------------------------VL
MAB_0855|M.abscessus_ATCC_1997 ----------------------------MAENTGGIYGLIAQIVRRAPVI
MSMEG_4741|M.smegmatis_MC2_155 ------------------------------MSRVGFSGLGRFIVR-HPLV
Mb1215|M.bovis_AF2122/97 --------------------------------------------------
Rv1183|M.tuberculosis_H37Rv --------------------------------------------------
MLBr_01231|M.leprae_Br4923 -------------------------------------------------M
MAV_1761|M.avium_104 -----------------------MSPTAPAGDEVEMRRIADFVVR-WPWL
MUL_3688|M.ulcerans_Agy99 --MSESNSGASISTEDTGPIEIGAATGGAPNRERGHRPVIPHTIRILAVP
Mvan_0312|M.vanbaalenii_PYR-1 VIGVWLGAAVVLALLFPQLETVVRQQSVDLIPRDAPSLQTVDRMSAAFGE
Mflv_4632|M.gilvum_PYR-GCK VIGVWLGAAVVLALLFPQLETVVRQQSVDLIPRDAPSLQTVDRMSAAFGE
MMAR_4836|M.marinum_M IIGMWVVTAAALAVLFPQLETVVRQQSVNLIPRDAPSLQTVDRMGAAFGE
TH_3450|M.thermoresistible__bu VIGTWLAVAVVLALLFPQLETVVRQQSVDLIPRDVPSFQTLDRMSAAFGE
MAB_0855|M.abscessus_ATCC_1997 VIGLWIGLAAVLALTAPSLQKAIEDHPVDLLPKDAPVMETTRQMVESFQE
MSMEG_4741|M.smegmatis_MC2_155 VIASWLAVAGVLLAAVPSLPAVAERNPPGFLPADSEVFAAGNAMQEAFNE
Mb1215|M.bovis_AF2122/97 MVGCWVALALVLPMAVPSLAEMAQRHPVAVLPADAPSSVAVRQMAEAFHE
Rv1183|M.tuberculosis_H37Rv MVGCWVALALVLPMAVPSLAEMAQRHPVAVLPADAPSSVAVRQMAEAFHE
MLBr_01231|M.leprae_Br4923 VIGCWTLLALMLPMTVPSLTELTQRHPVVILPVDAPSSVAAKKISQAFHE
MAV_1761|M.avium_104 VIGFWAALAVALPLAFPSLAEMAQKHPLAILPGNAPSNVAARQMTEAFHE
MUL_3688|M.ulcerans_Agy99 IILGWVLLTVLVNVVVPSLEVVSEQHSAPMTPMDAPSMKAMMRLGHNFRE
:: * : : *.* . :. . * : : : * *
Mvan_0312|M.vanbaalenii_PYR-1 EGSKTMVFVAMEDPNGLTPTARQRYGELVSRLQSEGDHVLLVQDLLADPI
Mflv_4632|M.gilvum_PYR-GCK EGSKTMVFVAMEDPTGLTPTARQRYGELVRRLQAEGDHVLLVQDLLADPI
MMAR_4836|M.marinum_M QGSKTTIFVAMEDPAGLTAPVRQRYNTMISRLRADSEHVRLVQDLLADPV
TH_3450|M.thermoresistible__bu QGSKTTVFVAMEDPAGLTPAARDRYEAMVSRLRADTDHVLLVQDLLADPV
MAB_0855|M.abscessus_ATCC_1997 SGAQNILLIVLTNENGLTPADEQTYRILAARMREDTRDVSMVQDFITKPP
MSMEG_4741|M.smegmatis_MC2_155 TGGGNVAIAILSNENGLTPADEETYRALVDKLRADTEYVLSTQDFVTIPE
Mb1215|M.bovis_AF2122/97 SGSENILVVLLTDEKGLGAADENVYHTLVDRLRNDAKDVVMLQDFLTTPP
Rv1183|M.tuberculosis_H37Rv SGSENILVVLLTDEKGLGAADENVYHTLVDRLRNDAKDVVMLQDFLTTPP
MLBr_01231|M.leprae_Br4923 VDSENVLIVLLTDDKGLGPADETVYRTLVDRLRNDTKDVVVLQDFLSTPP
MAV_1761|M.avium_104 SGSDDLLLVALTDEKGLGPADEAVYRRLVDALRRDTRDVVMVQDFISAPP
MUL_3688|M.ulcerans_Agy99 FDSNSTVMIVLEGQHKLGDDAHQYYDSLIRQLRQDPEHIQHIQDFWGDRL
.. . : . * . * : :: : : **:
Mvan_0312|M.vanbaalenii_PYR-1 TEAQAVSVDRKAWYLPVGVAGTLGDPTAAESVNAVRDIAAE-------VF
Mflv_4632|M.gilvum_PYR-GCK TEAQAVSADRKAWYLPVGVTGTLGDPTAAESLNAVRDIAAE-------VF
MMAR_4836|M.marinum_M TASQAVSQDGKAWYVPVGVAGTLGDVKAAESVQAVRTIAAQ-------AF
TH_3450|M.thermoresistible__bu TATQAVSQDGKAWYLPVGVAGTLGDPTAAESVQAVRALAAE-------AF
MAB_0855|M.abscessus_ATCC_1997 LREMMSSTDGKAWYLPVGLQGELATPESGKAYVGALKIIKD-------AT
MSMEG_4741|M.smegmatis_MC2_155 LRQVMTSEDNKAWQLPISAAGTMGTAEGQNAYRQIVDTVKS-------ST
Mb1215|M.bovis_AF2122/97 LREVLGSKDGKAWILPIGLAGDLGTPKSYHAYTDVERIVKR-------TV
Rv1183|M.tuberculosis_H37Rv LREVLGSKDGKAWILPIGLAGDLGTPKSYHAYTDVERIVKR-------TV
MLBr_01231|M.leprae_Br4923 LHELLVSKDGKAWILPIVLAGELGTSASYQAYAGVAGIVKQTLE----ST
MAV_1761|M.avium_104 LRSAVTSKDRKAWVLPVGIAGELGTPQSYAAFNRIAGIVKQTLEKHENGP
MUL_3688|M.ulcerans_Agy99 TAAGAQSADGKSAYVMVNLAGNQGTTLANESVEAVRDVINR-------TH
* * *: : : * . . :
Mvan_0312|M.vanbaalenii_PYR-1 TGSTTTVHVTGPPATFSDMIASAEHDLLLISIATAGVIALILLIVYRSVF
Mflv_4632|M.gilvum_PYR-GCK TGSTTTVQVTGPPATFSDMIASAEHDLLLISIATAGVIALILLIVYRSVF
MMAR_4836|M.marinum_M SGSPTNVRVTGPPATFHDQIASAEEDLVVISIATAGLIAMILLVVYRSVF
TH_3450|M.thermoresistible__bu ADSSTTVRVTGPPATFSDQIGSAEHDLVLISIATAGLIALILLIVYRSVF
MAB_0855|M.abscessus_ATCC_1997 QGTSLKAFTTGPTATVGDLTVVGERDLHKVEITTAALVLLILLIVYRNPV
MSMEG_4741|M.smegmatis_MC2_155 ANTSLSAEVIGPAATFEDVVKIGERDQHVIEIATVLIVLMILIIVYRNLV
Mb1215|M.bovis_AF2122/97 AGTTLTANVTGPAATVADLTDAGARDRASIELAIAVMLLVILMVIYRNPV
Rv1183|M.tuberculosis_H37Rv AGTTLTANVTGPAATVADLTDAGARDRASIELAIAVMLLVILMVIYRNPV
MLBr_01231|M.leprae_Br4923 AGSSLKANLTGPASTVADLTDAGARDRTSIELVIAVLLLTILMIIYRNPI
MAV_1761|M.avium_104 AATSLTVSLTGPAATVADLTVAGERDRLPIELAIAVLVLVVLLVVYRSAV
MUL_3688|M.ulcerans_Agy99 EPAGVKAYVTGPAALSDDMHLIGNASLATITMFTLGAIAVMLLLVYRSIV
: .. **.: * . . : : : :*:::**. .
Mvan_0312|M.vanbaalenii_PYR-1 TALLPLLVIGLSLAVGRGVLSALGEMGMP-VSQFTVAFMTAILLGAGTDY
Mflv_4632|M.gilvum_PYR-GCK TALLPLLVIGLSLAVGRGVLSALGEMGMP-VSQFTVAFMTAILLGAGTDY
MMAR_4836|M.marinum_M TALLPLLVIGVSLAVGRGVLSALGESGMP-VSQFTIAFMTVILLGAGTDY
TH_3450|M.thermoresistible__bu TALLPLLVIGVSLAVGRGVLSALGEMGMP-VSQFTVAFMTAILLGAGTDY
MAB_0855|M.abscessus_ATCC_1997 TMMLPLIVVGVSLGIAQAAVGGLAQMGLS-ISNQTLTFMTAMMMGAGVDY
MSMEG_4741|M.smegmatis_MC2_155 AMLLPLLMIGMALVVAEQSVAGLGAIHLIGLGPQTLMLMTAMMMGAGTDY
Mb1215|M.bovis_AF2122/97 TMLLPLVTIGASLMTAQALVAGVSLVGGLAVSNQAIVLLSAMIAGAGTDY
Rv1183|M.tuberculosis_H37Rv TMLLPLVTIGASLMTAQALVAGVSLVGGLAVSNQAIVLLSAMIAGAGTDY
MLBr_01231|M.leprae_Br4923 TMLLPLITIGASLMTAQAVVSGVSVLAGLAVSNQMIVLLSAMIAGAGTDY
MAV_1761|M.avium_104 TMLLPLVTILLSLVIAQAAVAGYSQLTGSGVSNQSIVFLSAIMAGAGTDY
MUL_3688|M.ulcerans_Agy99 TTVIQLFMTGIALASSRGVVAVLGYHNVFGLTTFAANILTMLAIAAGTDY
: :: *. :* .. :. . : ::: : .**.**
Mvan_0312|M.vanbaalenii_PYR-1 TVFLISRYHEQRRAQ----VPADQAIIHATASIGRVILASAATVALAFLA
Mflv_4632|M.gilvum_PYR-GCK TVFLISRYHEQRRAQ----VPADQAIIHATASIGRVILASAATVALAFLA
MMAR_4836|M.marinum_M SVFLISRYHEQRRQN----VPPDLSVINATATIGRVILASAATVAFAFLA
TH_3450|M.thermoresistible__bu TVFLISRYHEQRRAQ----VAPEQAAIYATASIGRVILASAATVAFAFLA
MAB_0855|M.abscessus_ATCC_1997 AVFLISRYHEYIKQG----LASDDAVAAALESIGKVVAASAATVAVTFLG
MSMEG_4741|M.smegmatis_MC2_155 AIFLFSRYHECVRSG----LSSDDAVVEALDSIGKVIAGSAGTVAITFMG
Mb1215|M.bovis_AF2122/97 AVFLISRYHEYVRLG----EHPERAVQRAMMSVGKVIAASAATVGITFLG
Rv1183|M.tuberculosis_H37Rv AVFLISRYHEYVRLG----EHPERAVQRAMMSVGKVIAASAATVGITFLG
MLBr_01231|M.leprae_Br4923 AVFLISRYHDYIRMGSGSAQDAGCAVRQALISLGKVIAASAATVGITFLG
MAV_1761|M.avium_104 AVFLISRYHDFLRRG----DDFDQAVRKALISIGKVITASASTVGITFLL
MUL_3688|M.ulcerans_Agy99 GIFLVGRYQEARQAG----EDRQDAYYTTFRGVAPVVLGSGLTIAGATYC
:**..**:: : : : :. *: .*. *:. :
Mvan_0312|M.vanbaalenii_PYR-1 MVFARLSVFAALGPACAIAVLFGFLATVTLLPPVLSLAAERG-IGEPKSD
Mflv_4632|M.gilvum_PYR-GCK MVFARLSVFAALGPACAIAVLFGFLATVTLLPPVLSLAAKRG-IGEPKPD
MMAR_4836|M.marinum_M MVFAKLSVFAALGPACAIAVFVGFAATVTLFPPVLALAAKRG-IGEPKAD
TH_3450|M.thermoresistible__bu MVFARLSVFAALGPACAIAVLFGFLATVTLLPPVLALAAKRG-IGDPKPD
MAB_0855|M.abscessus_ATCC_1997 MGFTKLGILSTVGPALSVSILIAFVASVTFLPAVLVLVGRRG-WITPRKA
MSMEG_4741|M.smegmatis_MC2_155 LAFTDLGVFSTVGPALSVTIGFGFVASVTLLPAMVVLAGRRG-WVKPRKD
Mb1215|M.bovis_AF2122/97 MRFAKLGVFSTVGPALAIGIAVSFLAAVTLLPAILVLASPRG-WVAPRGE
Rv1183|M.tuberculosis_H37Rv MRFAKLGVFSTVGPALAIGIAVSFLAAVTLLPAILVLASPRG-WVAPRGE
MLBr_01231|M.leprae_Br4923 MSFTKIRVFSTVGPALAIGIAVAFLAAVTLMPALLVLAGTRG-WVAPRRD
MAV_1761|M.avium_104 IGFARMGVFKTVGISSAIGIGVAFLAAVTLLPAIMVLAGPRG-WIRPRRE
MUL_3688|M.ulcerans_Agy99 LSFARLPWFNTMGAPVAIGMLVVVLAGLTLGPAVVFVGSRFHPFESKRAA
: *: : : ::* . :: : . . * :*: *.:: : . :
Mvan_0312|M.vanbaalenii_PYR-1 RTRRYWNSVAVAVVRRPVPLLIVSLVILLALSAAAATIKISYDDRKGQPA
Mflv_4632|M.gilvum_PYR-GCK RTRRYWNSVAVAVVRRPVPLLIVSLVILLALSAAAATIKISYDDRKGQPD
MMAR_4836|M.marinum_M RTRRYWNWIAVAVVRRPVPLLVASLALVLGLAAVALTMHISYDDRRGQPA
TH_3450|M.thermoresistible__bu RTRRYWNSVAVAVVRRPVTLLTISLAVLLALSAVAVTINISYDDRKGQPA
MAB_0855|M.abscessus_ATCC_1997 YANKIWHRSGINIVKRPGAHLAVSLVVLVILATCGAMVKFGYDDRKNLPP
MSMEG_4741|M.smegmatis_MC2_155 LTGRIWRRSGVHIVRKPVIHLVASLTVLLALAGCAMLVNFNYDDRKNLPD
Mb1215|M.bovis_AF2122/97 RMATFWRRAGTRIVRRPKAYLGASLIGLVALASCASLAHFNYDDRKQLPP
Rv1183|M.tuberculosis_H37Rv RMATFWRRAGTRIVRRPKAYLGASLIGLVALASCASLAHFNYDDRKQLPP
MLBr_01231|M.leprae_Br4923 RAGAFWRRTGVRIVRRPVAYLSASMVILIVLALCASLVRFNYDDRKQIPA
MAV_1761|M.avium_104 LTTGLWRRSGIRIVRRPRAHLVASVLVLIILASCAGLVRYNYDDRKALRP
MUL_3688|M.ulcerans_Agy99 NRGRLWRRVGTAVVRWPAPILALSGAIVLVGMVALPGFKTSYNDRYYLPA
*. . :*: * * * :: . .*:**
Mvan_0312|M.vanbaalenii_PYR-1 TTASNQGYHLLDRHFRKDVVITEFLVVENPTDMRTGKGLADLDEMASRVS
Mflv_4632|M.gilvum_PYR-GCK TTASNQGYHLLDRHFRKDVVISEFLVVENPTDMRTGKGLADLDEMASRVS
MMAR_4836|M.marinum_M TTASNEGYRLLDRHFRKDAIVTEFMVVESPTDMRTSKALADLDEMASRVS
TH_3450|M.thermoresistible__bu DTASNQGYQLLDRHFRKDVVFTEFLVVENPTDMRTGKGLADLDEMASRVA
MAB_0855|M.abscessus_ATCC_1997 WADSNQGYAAIEKHFPVNSTLPQYLYIKSPHDLRTPRGLADLEQMAARVS
MSMEG_4741|M.smegmatis_MC2_155 DAHSNMGYAALDKHFPVSSTVQQFILIQSPHDLRSPKALADMEQMAQRVS
Mb1215|M.bovis_AF2122/97 SDPSSVGYAAMEHHFSVNQTIPEYLIIHSAHDLRTPRGLADLEQLAQRVS
Rv1183|M.tuberculosis_H37Rv SDPSSVGYAAMEHHFSVNQTIPEYLIIHSAHDLRTPRGLADLEQLAQRVS
MLBr_01231|M.leprae_Br4923 SDESSVGYAALESHFPVGQAIPEYLLIQSPHDLRTPRALADMAELAQRVS
MAV_1761|M.avium_104 SAPSSVGYAALERHFPVNQSIPEYILIRSPHDLRTPQALADLEQLADRVS
MUL_3688|M.ulcerans_Agy99 SAPSNLGEAAADRHFSHARMNPDMLMVEAEHDMRNPADMLVLDKVAKNVI
*. * : ** : : :. *:*. : : ::* .*
Mvan_0312|M.vanbaalenii_PYR-1 QIPGVTKVSGVTRPTGERLDQAELAWQNGQIGDKMAGAVAEGNSRKDDLA
Mflv_4632|M.gilvum_PYR-GCK QIPGVTKVSGVTRPTGERLDQAELAWQNGQIGDKMAGAVAEGNSRKDDLA
MMAR_4836|M.marinum_M QLPGVTKVSGVTRPTGARLDQAQLSWQNGEIGDKMAGAVAKGDAHKDDLA
TH_3450|M.thermoresistible__bu QIPGVTKVSGVTRPTGERLDQAKLAWQNQQIGDKMADAVADGNARKADLA
MAB_0855|M.abscessus_ATCC_1997 QVPGVDKVRGITRPTGEPLEEAKLSYQAGEVGGKLGDASNLIDARTRDLD
MSMEG_4741|M.smegmatis_MC2_155 QLPDIEMVRGVTRPTGEMLQEARATWQAGEVGGKLNDASTLIDANDANLS
Mb1215|M.bovis_AF2122/97 QIPGVAMVRGVTRPNGETLEQARATYQAGQVGNRLGGASRMIDERTGDLN
Rv1183|M.tuberculosis_H37Rv QIPGVAMVRGVTRPNGETLEQARATYQAGQVGNRLGGASRMIDERTGDLN
MLBr_01231|M.leprae_Br4923 QIPGIALVRGVTRPTGKPLEETSATYQAGMVGKQLGSASHLIGESTGDLN
MAV_1761|M.avium_104 QLPNVSVVSGITRPTGNVPEQFRATYQAGAIGSMLAGGSTMINDQTDDLN
MUL_3688|M.ulcerans_Agy99 RTVGIAMIQDITRPLGIPIQHSSIPFQNSMQSQTMMQNMAFLKERMADMT
: .: : .:*** * :. .:* . : ::
Mvan_0312|M.vanbaalenii_PYR-1 KLTGGADQLADGLAQLDSTVRTALTPLAEILTQAQSAGTQVNQFRPLLQQ
Mflv_4632|M.gilvum_PYR-GCK KLTGGADQLADGLAQLDSTVRTALTPLAGILTQAQSAGTQVNQFRPGLLR
MMAR_4836|M.marinum_M KLTHGADQLAGGLAQLDTTLRTALTPLTGLLTQAQSSGSQVQRFRPLLQQ
TH_3450|M.thermoresistible__bu KLTNGADQLAAGLAQLDTTLRTALAPLSGILSQAQSAGTQMQQFRPLLQQ
MAB_0855|M.abscessus_ATCC_1997 KLAAGGHTLADKLGQVRDSVKNSLGTARALVEVLAQLRGS-GRTGT-LAD
MSMEG_4741|M.smegmatis_MC2_155 TLSGGAHKLADVLGQISTQVTNALVTVRPLAGALADMETKYGGEKT-LDQ
Mb1215|M.bovis_AF2122/97 RLASGANLLADNLGDVRGQVSRAVAGVRSLVDALAYIQNQFGGNKT-FNE
Rv1183|M.tuberculosis_H37Rv RLASGANLLADNLGDVRGQVSRAVAGVRSLVDALAYIQNQFGGNKT-FNE
MLBr_01231|M.leprae_Br4923 RLASGAGLLADKLGDVRIQVGQAVAGISGLLDNLAFAQKMFGDSKT-LGE
MAV_1761|M.avium_104 RLARGAGTLADNLGDVRGQVNQLAASVRELENAFSSTKNQYSGDAL-VNQ
MUL_3688|M.ulcerans_Agy99 KMADEMQVLIDTTERMYAVMRELDTTTTDMARVTAETSTITDELRDHLAE
:: * : : : .
Mvan_0312|M.vanbaalenii_PYR-1 LSATAPAVDQAIQSSPGLRPLANQAQNAISQLDPLVGALNTSPWCATTPQ
Mflv_4632|M.gilvum_PYR-GCK AFRTA--------DFAGIMPR----------------AVNSCIRCGLHAA
MMAR_4836|M.marinum_M LSATAPAVDQAIRTGPGLRQQADQAQNAIAAIDPLVGALNTSPWCATTPE
TH_3450|M.thermoresistible__bu LSATAPAVDQAIQAGPGLRPWADQAAHAIAILDPLVGALNTAPWCATTPQ
MAB_0855|M.abscessus_ATCC_1997 LDSVDKLVTSMHSLGDAIEANAQGASEVYGWIEPVARVLVGNPACDMDPG
MSMEG_4741|M.smegmatis_MC2_155 IDQSAELVANMRSLGRAMGVNLARITDVYDWSAPMVRALNVSPECNLDPA
Mb1215|M.bovis_AF2122/97 IDNAARLVSNIHALGDALQVNFDGIANSFDWLDSVVAALDTSPVCDSNPM
Rv1183|M.tuberculosis_H37Rv IDNAARLVSNIHALGDALQVNFDGIANSFDWLDSVVAALDTSPVCDSNPM
MLBr_01231|M.leprae_Br4923 IDTAGKLVSSMRALGNMFGINFSTTMNDINWVGAVVIALDSSVLCDTNPI
MAV_1761|M.avium_104 VDIAARLVDHVNSLSNAMGWNFTAAKNMFAWIGPVLAALQGNPVCDADSS
MUL_3688|M.ulcerans_Agy99 FDDFWR---------------------------PMRSYFYWEKHCFDVPI
. * .
Mvan_0312|M.vanbaalenii_PYR-1 CAQIRDQVKILVTLRDSGFFTQIADLGDRYDPATN-ATVGGTLANVQNAV
Mflv_4632|M.gilvum_PYR-GCK CG-----------------------------SPTR-SEVCADYRTVR---
MMAR_4836|M.marinum_M CTQLRDQVQILVTLRHTGFFNQLANLGDLYQPGS--DTAAGTVADVQNTI
TH_3450|M.thermoresistible__bu CAQIRDQVQVLVTLRNSGFFNQVADLGDRYNPATG-ATVAETLADIRNAV
MAB_0855|M.abscessus_ATCC_1997 CRSSRDEMNKFLETKQDGTRDKIVELGRELKSVDNDKQISSTIARLRTAL
MSMEG_4741|M.smegmatis_MC2_155 CAASRSDLQRIVEAKDNGNLDKFAELGRQLESTEGDETLDEAVSGLQQSI
Mb1215|M.bovis_AF2122/97 CGNARVQFHKLQTARDNGTLDKVVGLARQLQSTRSPQTVSAVVNDLGRSL
Rv1183|M.tuberculosis_H37Rv CGNARVQFHKLQTARDNGTLDKVVGLARQLQSTRSPQTVSAVVNDLGRSL
MLBr_01231|M.leprae_Br4923 CADARAQFHKLLTASEDGTLDNIAHLWKQLGSTQSSQTIGATVSGLEKTL
MAV_1761|M.avium_104 CSATRATFEQLVGPRGQADLDAIDDLSHQLQAYPDKRALKASTDRLRNAF
MUL_3688|M.ulcerans_Agy99 CWSFRS----------------------LFDSLDGIDKLSEKFSELTEDI
* . :
Mvan_0312|M.vanbaalenii_PYR-1 ASLDKAFGAL--GDPADLATNLRRLQDGIGQLASGAQALATGVRTLADSN
Mflv_4632|M.gilvum_PYR-GCK -----------------YSGQYQLLLSSASDTPCGAHVHFSGLQRMILR-
MMAR_4836|M.marinum_M TSLDKTFGAL--GDPADLAGNIRRLQSGISQLASGAQALATGVHTLADSN
TH_3450|M.thermoresistible__bu TAMDKAFGAL--GDPADLAGNIGRLQDGISQLASGAQALATGVHTLVDSN
MAB_0855|M.abscessus_ATCC_1997 NSIDTNLRRLGLSDSYGIQKRFTEVLTGVNSLADGSAQLAEGVQMLVDQT
MSMEG_4741|M.smegmatis_MC2_155 KEATAAARELGLEDASSVKRQLDQLEQGVNLLADSSHQLAQGVQLLVDQT
Mb1215|M.bovis_AF2122/97 NSVVRSLKSLGLDNPDAARARLISMQNGANDLASAGRQVADGVQMLVDQT
Rv1183|M.tuberculosis_H37Rv NSVVRSLKSLGLDNPDAARARLISMQNGANDLASAGRQVADGVQMLVDQT
MLBr_01231|M.leprae_Br4923 TAVNTSLRSLGLDNPNVMRSKMIGLQNGVNDLASAGRRIADGVAVLVDQT
MAV_1761|M.avium_104 AKLNDVLRAMGMDRPGGLQSNLTTLQNGADQFAGGSRQVADAVAQLVDKV
MUL_3688|M.ulcerans_Agy99 QR---------------TAGLTSQMLTLIPPMIATMKTTKALTLTMQSTF
: :
Mvan_0312|M.vanbaalenii_PYR-1 IEMLSGMSQIATQLQNSSRAAADSDSSSGFYLPANAFENRQFTDVAEQFL
Mflv_4632|M.gilvum_PYR-GCK -----------ARYPNIFRSAPARLS----------YQGRRF--------
MMAR_4836|M.marinum_M IEMLSGMSQIATQLQNSARTTAGSDNASGFYLPTNAFENRQFADVAKHFL
TH_3450|M.thermoresistible__bu LEMLSGMSQIATQLQNSARASADSDSSSGFYLPPNTFENRQFADVAKQFL
MAB_0855|M.abscessus_ATCC_1997 KQMGGQLGDASTLLVAAKRDAA-PGSMSGFYIPQQVLTQDSFKTAAAAFV
MSMEG_4741|M.smegmatis_MC2_155 RNMGQGLDQASQFLLAMKRDAS-DPQMSGFYIPPQILTQEEFNKAAALFV
Mb1215|M.bovis_AF2122/97 KNMGIGLNQASAFLMAMGNDAS-QPSMAGFNVPPQVLKSEEFKKVAQAFI
Rv1183|M.tuberculosis_H37Rv KNMGIGLNQASAFLMAMGNDAS-QPSMAGFNVPPQVLKSEEFKKVAQAFI
MLBr_01231|M.leprae_Br4923 RTMGTSLARASAFLMEMGQDAS-QPSMAGFNVPPQLLNTEDFKKLVQAFI
MAV_1761|M.avium_104 KQLGAGLSESAAFLLSLKHDAA-HPAMAGFNIPAQLLRLPQFQEAAKVFI
MUL_3688|M.ulcerans_Agy99 SAMLDQMDELSNTAIVMGQSFDASKNDDFFYLPPEAFDNPDFQTGLRMFL
. *
Mvan_0312|M.vanbaalenii_PYR-1 SPDGKTARFMIESSHDPYSVEAMDLASRITDTANTARPNTSLADATVSVA
Mflv_4632|M.gilvum_PYR-GCK --------------------------------------------------
MMAR_4836|M.marinum_M SPDGKTARFAIESSYDPYSSDAMNLAHKITEVADAARPNTSLANATVSMA
TH_3450|M.thermoresistible__bu SPDGKTARFAIESSHDPYSVDAMNLAHTITDVADAARPNTSLAHATVSVA
MAB_0855|M.abscessus_ATCC_1997 SADGHAVRYLVQSNLNPFSPEAMDQVRAIQEAARSAQPNTTLSDASISMA
MSMEG_4741|M.smegmatis_MC2_155 SPDGRSVRYLVQTALDPFGTAAMDQVKDIVKTAESARPNTSLTDAKISLV
Mb1215|M.bovis_AF2122/97 SPDGHTVRYFIQTDLNPFSTAAMDQVNTIIDTAKGAQPNTSLADASISMS
Rv1183|M.tuberculosis_H37Rv SPDGHTVRYFIQTDLNPFSTAAMDQVNTIIDTAKGAQPNTSLADASISMS
MLBr_01231|M.leprae_Br4923 SPDGHSVRYFIQTDLNPFSSAAMDQVNTILNVATGAQPNTTLSDASIYLS
MAV_1761|M.avium_104 SPDGHSVRYLVQSKLSPFSTQAMDQVDAITATARGAQPNTALADAEVSMA
MUL_3688|M.ulcerans_Agy99 SPDGKSARFFITHQGDPMTPEGISRVDAERTAAQEGLKQSSLSDAKVYLG
Mvan_0312|M.vanbaalenii_PYR-1 GFPAVNSDIQRLLWADFAQLAIATIIIVGVILVLLLRALLAPLYLLGTVV
Mflv_4632|M.gilvum_PYR-GCK --------------------------------------------------
MMAR_4836|M.marinum_M GFPAVNSDIQRLLSADFHQLAFATLVIVGLILVVLLRALVAPLYLLGTVV
TH_3450|M.thermoresistible__bu GFPAVNSDIARLLWADFAQLAIATIVIVGLILVLLLRALLAPIYLLGTVV
MAB_0855|M.abscessus_ATCC_1997 GLSAMYNDIRNYYNHDLRFIIVLTVIVVLLILVALLRAIVAPLYLIGSVI
MSMEG_4741|M.smegmatis_MC2_155 GFSSIQNEMRNYYDGDLRFIITVTLIVVFLILAALLRSIIAPIYLVLSVV
Mb1215|M.bovis_AF2122/97 GYPVMLRDIRDYYERDMRLIVAVTVVVVILILMALLRAIVAPLYLVGSVV
Rv1183|M.tuberculosis_H37Rv GYPVMLRDIRDYYERDMRLIVAVTVVVVILILMALLRAIVAPLYLVGSVV
MLBr_01231|M.leprae_Br4923 GYTVTLRDTRDYYDRDLQLIVIVTMIVVLLILMALLRSIVAPIYLVGSVI
MAV_1761|M.avium_104 GYTVGLKDTRDYYQHDIKFIIAVTLLVVLLTLMALLRAIVAPLYLVATVV
MUL_3688|M.ulcerans_Agy99 GTAATFKDMADGEKYDLMIAVVSALTLIFLIMLLLTRSVVAALVIVGTAA
Mvan_0312|M.vanbaalenii_PYR-1 LNYLASLGIGVVVFQWGLGHEIAWPVPLLAFIILVAVGADYNMLLVSRLR
Mflv_4632|M.gilvum_PYR-GCK --------------------------------------------------
MMAR_4836|M.marinum_M LNYGAALGLGTLVFQYGLGKEIAWPVPLLAFIILVAVGADYNMLLISRLR
TH_3450|M.thermoresistible__bu LNYLASLGIGVLVFQYLLGHEIAWPVPLLAFIILVAVGADYNMLLVSRLR
MAB_0855|M.abscessus_ATCC_1997 ISYASAVGIGVIAFQFIGGQPLSWSVPGMAFIVLVAVGADYNLLFISRIR
MSMEG_4741|M.smegmatis_MC2_155 LSYMSALGIGVVFFQFILGKEIVWTVPGMAFLVLVAVGADYNLLLISRIR
Mb1215|M.bovis_AF2122/97 ISYMSAIGLGVVVFQVFLGQELHWSVPGLAFVVLVAVGADYNMLLASRLR
Rv1183|M.tuberculosis_H37Rv ISYMSAIGLGVVVFQVFLGQELHWSVPGLAFVVLVAVGADYNMLLASRLR
MLBr_01231|M.leprae_Br4923 VSYLSALGLCVLVFQVLLRQQLHWSVPGLAFVVLVAVGADYNMLLASRLR
MAV_1761|M.avium_104 ISYLSAVGVGVLVFQFLLGQQLHWSVPPLAFVVLVAVGADYNMLLVSRMR
MUL_3688|M.ulcerans_Agy99 SSIAASFGLSVLIWQDLFGIKIHWIVAALSVIILLAVGSDYNLLLVSRFR
Mvan_0312|M.vanbaalenii_PYR-1 EESGTNIRVGVLRTVANTGAVITSAGLIFAASMFGLMVGSVAIMIQAGLI
Mflv_4632|M.gilvum_PYR-GCK --------------------------------------------------
MMAR_4836|M.marinum_M EESAHNIRVGVLRTVANTGSVITSAGLIFAASMFGLIAGSIAIMIQAGFI
TH_3450|M.thermoresistible__bu EESGTNIRVGVLRTVANTGSVITSAGVIFAASMFGLMFGSIAIMIQAGFI
MAB_0855|M.abscessus_ATCC_1997 DESPDGIRSGVIKTVKSTGGVITSAGVIFAASMFGLLIGNLQSMVEAGFI
MSMEG_4741|M.smegmatis_MC2_155 DEAAHGMRTAVIRTIGATGGVITSAGLIFAASMFGLTFSSLLAAVQIGFI
Mb1215|M.bovis_AF2122/97 DESALGVRSSVIRTVRCTGGVITAAGLIFAASMSGLLFSSIGTVVQGGFI
Rv1183|M.tuberculosis_H37Rv DESALGVRSSVIRTVRCTGGVITAAGLIFAASMSGLLFSSIGTVVQGGFI
MLBr_01231|M.leprae_Br4923 DESSHGLRASVIRTVRSTGGVITAAGLIFAASMFGLLLSSIATVVQAGFV
MAV_1761|M.avium_104 DESPHSMRYGIIRTLSSTGGVITAAGLIFAASMSGLLFSSIGTVVQGGVV
MUL_3688|M.ulcerans_Agy99 EEIHAGLKTGIIRSMAGTGGVVTAAGLVFAFTMASMLGSDLRVLGQFGST
Mvan_0312|M.vanbaalenii_PYR-1 IGFGLLLDTFLVRTLTVPAIATLLREASWWP--------------TKATN
Mflv_4632|M.gilvum_PYR-GCK --------------------------------------------------
MMAR_4836|M.marinum_M IGCGLLLDTFVVRTLTVPAIATLLREASWWP--------------QRKPL
TH_3450|M.thermoresistible__bu VGCGLLLDTFLVRTLTVPAIATLLREASWWP--------------QPNRA
MAB_0855|M.abscessus_ATCC_1997 IGMGLLLDTFLVRTITIPALVVLCGQANWWPSASVESWFRQRFSRSKPDA
MSMEG_4741|M.smegmatis_MC2_155 IGVGLLLDTFLVRTITVPAAAVLIGKLSWWP--------------TKPPA
Mb1215|M.bovis_AF2122/97 IGVGILIDTFVVRTITVPAMATLLGRASWWP--------------GHPWQ
Rv1183|M.tuberculosis_H37Rv IGVGILIDTFVVRTITVPAMATLLGRASWWP--------------GHPWQ
MLBr_01231|M.leprae_Br4923 LGSGILLDTFIVRTITVPAVAALLRRASWWP--------------ARPWG
MAV_1761|M.avium_104 IGVGILLDTFLVRTVTVPAIAALAGRANWWP--------------SRIAV
MUL_3688|M.ulcerans_Agy99 VCIGLLLDTLIVRTLLMPSIATLLGRWFWWP------------QVVHPRG
Mvan_0312|M.vanbaalenii_PYR-1 PRRGDPKQKA---------------------------
Mflv_4632|M.gilvum_PYR-GCK -------------------------------------
MMAR_4836|M.marinum_M THNG---------------------------------
TH_3450|M.thermoresistible__bu R------------------------------------
MAB_0855|M.abscessus_ATCC_1997 QEGDCAVSDDPEAASGESSPEEPLISASREVELAGRR
MSMEG_4741|M.smegmatis_MC2_155 P---------------EPAPTEPTVAPAAQA------
Mb1215|M.bovis_AF2122/97 RCAPEEGQMSARMSARTKTVFQAVADGSKR-------
Rv1183|M.tuberculosis_H37Rv RCAPEEGQMSARMSARTKTVFQAVADGSKR-------
MLBr_01231|M.leprae_Br4923 NNA----------------------------------
MAV_1761|M.avium_104 RRNPVSGQP----------------------------
MUL_3688|M.ulcerans_Agy99 DNARPRVAAPTH-------------------------