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M. marinum M MMAR_4836 (-)

annotation: MmpL family transport protein
coordinates: 5892201 - 5895269
length: 1022

MADYGWVSSGVATLSRPVRERLQKVAAGEGAYSDRLARLAGFSIRHKVLIIGMWVVTAAALAVLFPQLET
VVRQQSVNLIPRDAPSLQTVDRMGAAFGEQGSKTTIFVAMEDPAGLTAPVRQRYNTMISRLRADSEHVRL
VQDLLADPVTASQAVSQDGKAWYVPVGVAGTLGDVKAAESVQAVRTIAAQAFSGSPTNVRVTGPPATFHD
QIASAEEDLVVISIATAGLIAMILLVVYRSVFTALLPLLVIGVSLAVGRGVLSALGESGMPVSQFTIAFM
TVILLGAGTDYSVFLISRYHEQRRQNVPPDLSVINATATIGRVILASAATVAFAFLAMVFAKLSVFAALG
PACAIAVFVGFAATVTLFPPVLALAAKRGIGEPKADRTRRYWNWIAVAVVRRPVPLLVASLALVLGLAAV
ALTMHISYDDRRGQPATTASNEGYRLLDRHFRKDAIVTEFMVVESPTDMRTSKALADLDEMASRVSQLPG
VTKVSGVTRPTGARLDQAQLSWQNGEIGDKMAGAVAKGDAHKDDLAKLTHGADQLAGGLAQLDTTLRTAL
TPLTGLLTQAQSSGSQVQRFRPLLQQLSATAPAVDQAIRTGPGLRQQADQAQNAIAAIDPLVGALNTSPW
CATTPECTQLRDQVQILVTLRHTGFFNQLANLGDLYQPGSDTAAGTVADVQNTITSLDKTFGALGDPADL
AGNIRRLQSGISQLASGAQALATGVHTLADSNIEMLSGMSQIATQLQNSARTTAGSDNASGFYLPTNAFE
NRQFADVAKHFLSPDGKTARFAIESSYDPYSSDAMNLAHKITEVADAARPNTSLANATVSMAGFPAVNSD
IQRLLSADFHQLAFATLVIVGLILVVLLRALVAPLYLLGTVVLNYGAALGLGTLVFQYGLGKEIAWPVPL
LAFIILVAVGADYNMLLISRLREESAHNIRVGVLRTVANTGSVITSAGLIFAASMFGLIAGSIAIMIQAG
FIIGCGLLLDTFVVRTLTVPAIATLLREASWWPQRKPLTHNG
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. marinum MMMAR_4836--100% (1022)MmpL family transport protein
M. marinum MMMAR_2342-0.039.56% (1011) MmpL family transport protein
M. marinum MMMAR_4975-e-13731.88% (985) MmpL family transport protein

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb1549cmmpL120.040.61% (980) transmembrane transport protein MmpL12
M. gilvum PYR-GCKMflv_4632-0.075.39% (577) MMPL domain-containing protein
M. tuberculosis H37RvRv1522cmmpL120.040.71% (980) transmembrane transport protein MmpL12
M. leprae Br4923MLBr_01231mmpL100.038.00% (979) hypothetical protein MLBr_01231
M. abscessus ATCC 19977MAB_0855-0.038.83% (976) MmpL family protein
M. avium 104MAV_1761-0.038.68% (998) MmpL10 protein
M. smegmatis MC2 155MSMEG_4741-0.038.80% (987) MmpL protein
M. thermoresistible (build 8)TH_3450-0.081.51% (968) PUTATIVE MMPL domain protein
M. ulcerans Agy99MUL_0757mmpL51e-12530.97% (972) transmembrane transport protein, MmpL5
M. vanbaalenii PYR-1Mvan_0312-0.078.78% (985) MMPL domain-containing protein

CLUSTAL 2.0.9 multiple sequence alignment


MMAR_4836|M.marinum_M               MADYGWVSSGVATLSRPVRERLQKVAAGEGAYSDRLARLAGFSIR-HKVL
TH_3450|M.thermoresistible__bu      ------------------------------------------------VL
Mflv_4632|M.gilvum_PYR-GCK          -MTDGSADAPSQAKRPGRRANGSTDPADTREYSERLATLARFTLR-HKAL
Mvan_0312|M.vanbaalenii_PYR-1       -MTDGTADSPSQATRSGRGANGSPDPADTREYSERLAALARFTLR-HKAL
MAB_0855|M.abscessus_ATCC_1997      ----------------------------MAENTGGIYGLIAQIVRRAPVI
MSMEG_4741|M.smegmatis_MC2_155      ------------------------------MSRVGFSGLGRFIVR-HPLV
MLBr_01231|M.leprae_Br4923          -------------------------------------------------M
MAV_1761|M.avium_104                -----------------------MSPTAPAGDEVEMRRIADFVVR-WPWL
Mb1549c|M.bovis_AF2122/97           -----------------------MARHDEAKAGGLFDRIGNFVVR-WPLI
Rv1522c|M.tuberculosis_H37Rv        -----------------------MARHDEAKAGGLFDRIGNFVVR-WPLI
MUL_0757|M.ulcerans_Agy99           ----------------MTATTTDTPTDVVPPAEHPPRPFIPRMIRTFAVP
                                                                                      

MMAR_4836|M.marinum_M               IIGMWVVTAAALAVLFPQLETVVRQQSVNLIPRDAPSLQTVDRMGAAFGE
TH_3450|M.thermoresistible__bu      VIGTWLAVAVVLALLFPQLETVVRQQSVDLIPRDVPSFQTLDRMSAAFGE
Mflv_4632|M.gilvum_PYR-GCK          VIGVWLGAAVVLALLFPQLETVVRQQSVDLIPRDAPSLQTVDRMSAAFGE
Mvan_0312|M.vanbaalenii_PYR-1       VIGVWLGAAVVLALLFPQLETVVRQQSVDLIPRDAPSLQTVDRMSAAFGE
MAB_0855|M.abscessus_ATCC_1997      VIGLWIGLAAVLALTAPSLQKAIEDHPVDLLPKDAPVMETTRQMVESFQE
MSMEG_4741|M.smegmatis_MC2_155      VIASWLAVAGVLLAAVPSLPAVAERNPPGFLPADSEVFAAGNAMQEAFNE
MLBr_01231|M.leprae_Br4923          VIGCWTLLALMLPMTVPSLTELTQRHPVVILPVDAPSSVAAKKISQAFHE
MAV_1761|M.avium_104                VIGFWAALAVALPLAFPSLAEMAQKHPLAILPGNAPSNVAARQMTEAFHE
Mb1549c|M.bovis_AF2122/97           VIGCWIAVAAALTLLLPTLQAQAAKREQAPLPPGAPSMVLQKEMSAAFQE
Rv1522c|M.tuberculosis_H37Rv        VIGCWIAVAAALTLLLPTLQAQAAKREQAPLPPGAPSMVLQKEMSAAFQE
MUL_0757|M.ulcerans_Agy99           LILGWVLLIAVLNSVVPQLEVVGQMQAVSMSPDAAPSMISMKHIGKVFRE
                                    :*  *      *    * *      .     *           :   * *

MMAR_4836|M.marinum_M               -QGSKTTIFVAMEDPAGLTAPVRQRYNTMISRLRADSEHVRLVQDLLADP
TH_3450|M.thermoresistible__bu      -QGSKTTVFVAMEDPAGLTPAARDRYEAMVSRLRADTDHVLLVQDLLADP
Mflv_4632|M.gilvum_PYR-GCK          -EGSKTMVFVAMEDPTGLTPTARQRYGELVRRLQAEGDHVLLVQDLLADP
Mvan_0312|M.vanbaalenii_PYR-1       -EGSKTMVFVAMEDPNGLTPTARQRYGELVSRLQSEGDHVLLVQDLLADP
MAB_0855|M.abscessus_ATCC_1997      -SGAQNILLIVLTNENGLTPADEQTYRILAARMREDTRDVSMVQDFITKP
MSMEG_4741|M.smegmatis_MC2_155      -TGGGNVAIAILSNENGLTPADEETYRALVDKLRADTEYVLSTQDFVTIP
MLBr_01231|M.leprae_Br4923          -VDSENVLIVLLTDDKGLGPADETVYRTLVDRLRNDTKDVVVLQDFLSTP
MAV_1761|M.avium_104                -SGSDDLLLVALTDEKGLGPADEAVYRRLVDALRRDTRDVVMVQDFISAP
Mb1549c|M.bovis_AF2122/97           KIETSALLLVLLTNENGLGPADEAVYRKLIENLRADTQDKISVQDFLAVP
Rv1522c|M.tuberculosis_H37Rv        KIETSALLLVLLTNENGLGPADEAVYRKLIENLRADTQDKISVQDFLAVP
MUL_0757|M.ulcerans_Agy99           -GDSDSAAMIVLEGQEPLGAAAHKFYDKMITKLRADTKHVQSVQDFWGDP
                                            :  : .   * .. .  *  :   :: :       **:   *

MMAR_4836|M.marinum_M               VTASQAVSQDGKAWYVPVGVAGTLGDVKAAESVQAVRTIAAQAFSGS---
TH_3450|M.thermoresistible__bu      VTATQAVSQDGKAWYLPVGVAGTLGDPTAAESVQAVRALAAEAFADS---
Mflv_4632|M.gilvum_PYR-GCK          ITEAQAVSADRKAWYLPVGVTGTLGDPTAAESLNAVRDIAAEVFTGS---
Mvan_0312|M.vanbaalenii_PYR-1       ITEAQAVSVDRKAWYLPVGVAGTLGDPTAAESVNAVRDIAAEVFTGS---
MAB_0855|M.abscessus_ATCC_1997      PLREMMSSTDGKAWYLPVGLQGELATPESGKAYVGALKIIKDATQGT---
MSMEG_4741|M.smegmatis_MC2_155      ELRQVMTSEDNKAWQLPISAAGTMGTAEGQNAYRQIVDTVKSSTANT---
MLBr_01231|M.leprae_Br4923          PLHELLVSKDGKAWILPIVLAGELGTSASYQAYAGVAGIVKQTLEST---
MAV_1761|M.avium_104                PLRSAVTSKDRKAWVLPVGIAGELGTPQSYAAFNRIAGIVKQTLEKHENG
Mb1549c|M.bovis_AF2122/97           EMKELLASKDNKAWNLPITFAGDAASPETQAAFKRVAAIVKQTVAGT---
Rv1522c|M.tuberculosis_H37Rv        EMKELLASKDNKAWNLPITFAGDAASPETQAAFKRVAAIVKQTVAGT---
MUL_0757|M.ulcerans_Agy99           LTATGAQSGDGKAAYVQVKLAGNQGESLANESVEAVKTIVDSLQAPP---
                                           * * **  : :   *  .      :         .        

MMAR_4836|M.marinum_M               ----PTNVRVTGPPATFHDQIASAEEDLVVISIATAGLIAMILLVVYRSV
TH_3450|M.thermoresistible__bu      ----STTVRVTGPPATFSDQIGSAEHDLVLISIATAGLIALILLIVYRSV
Mflv_4632|M.gilvum_PYR-GCK          ----TTTVQVTGPPATFSDMIASAEHDLLLISIATAGVIALILLIVYRSV
Mvan_0312|M.vanbaalenii_PYR-1       ----TTTVHVTGPPATFSDMIASAEHDLLLISIATAGVIALILLIVYRSV
MAB_0855|M.abscessus_ATCC_1997      ----SLKAFTTGPTATVGDLTVVGERDLHKVEITTAALVLLILLIVYRNP
MSMEG_4741|M.smegmatis_MC2_155      ----SLSAEVIGPAATFEDVVKIGERDQHVIEIATVLIVLMILIIVYRNL
MLBr_01231|M.leprae_Br4923          -AGSSLKANLTGPASTVADLTDAGARDRTSIELVIAVLLLTILMIIYRNP
MAV_1761|M.avium_104                PAATSLTVSLTGPAATVADLTVAGERDRLPIELAIAVLVLVVLLVVYRSA
Mb1549c|M.bovis_AF2122/97           ----SLTVHLSGPIATVADLTELGEKDVRIIEIGAAVSVLIILILVYRNL
Rv1522c|M.tuberculosis_H37Rv        ----SLTVHLSGPIATVADLTELGEKDVRIIEIGTAVSVLIILILVYRNL
MUL_0757|M.ulcerans_Agy99           ----GVKVYVTGSAALVADQQLAGDRSLQLIEMVTFTVIIVMLLLVYRSI
                                          ..   *. : . *    . ..   :.:     :  :*:::**. 

MMAR_4836|M.marinum_M               FTALLPLLVIGVSLAVGRGVLSALGESGMP-VSQFTIAFMTVILLGAGTD
TH_3450|M.thermoresistible__bu      FTALLPLLVIGVSLAVGRGVLSALGEMGMP-VSQFTVAFMTAILLGAGTD
Mflv_4632|M.gilvum_PYR-GCK          FTALLPLLVIGLSLAVGRGVLSALGEMGMP-VSQFTVAFMTAILLGAGTD
Mvan_0312|M.vanbaalenii_PYR-1       FTALLPLLVIGLSLAVGRGVLSALGEMGMP-VSQFTVAFMTAILLGAGTD
MAB_0855|M.abscessus_ATCC_1997      VTMMLPLIVVGVSLGIAQAAVGGLAQMGLS-ISNQTLTFMTAMMMGAGVD
MSMEG_4741|M.smegmatis_MC2_155      VAMLLPLLMIGMALVVAEQSVAGLGAIHLIGLGPQTLMLMTAMMMGAGTD
MLBr_01231|M.leprae_Br4923          ITMLLPLITIGASLMTAQAVVSGVSVLAGLAVSNQMIVLLSAMIAGAGTD
MAV_1761|M.avium_104                VTMLLPLVTILLSLVIAQAAVAGYSQLTGSGVSNQSIVFLSAIMAGAGTD
Mb1549c|M.bovis_AF2122/97           VTMLVPLATIGASVVTAQGTLSGLAEFGLA-VNMQAIVFMSAVMIGAGTD
Rv1522c|M.tuberculosis_H37Rv        VTMLVPLATIGASVVTAQGTLSGLAEFGLA-VNMQAIVFMSAVMIGAGTD
MUL_0757|M.ulcerans_Agy99           ITAAIMLTMVVLGLLATRGGVAFLGYHRIIGLSTFATNLLVVLAIAAATD
                                    .:  : *  :  .:   .  :.  .      :.     :: .:  .*..*

MMAR_4836|M.marinum_M               YSVFLISRYHEQRRQN----VPPDLSVINATATIGRVILASAATVAFAFL
TH_3450|M.thermoresistible__bu      YTVFLISRYHEQRRAQ----VAPEQAAIYATASIGRVILASAATVAFAFL
Mflv_4632|M.gilvum_PYR-GCK          YTVFLISRYHEQRRAQ----VPADQAIIHATASIGRVILASAATVALAFL
Mvan_0312|M.vanbaalenii_PYR-1       YTVFLISRYHEQRRAQ----VPADQAIIHATASIGRVILASAATVALAFL
MAB_0855|M.abscessus_ATCC_1997      YAVFLISRYHEYIKQG----LASDDAVAAALESIGKVVAASAATVAVTFL
MSMEG_4741|M.smegmatis_MC2_155      YAIFLFSRYHECVRSG----LSSDDAVVEALDSIGKVIAGSAGTVAITFM
MLBr_01231|M.leprae_Br4923          YAVFLISRYHDYIRMGSGSAQDAGCAVRQALISLGKVIAASAATVGITFL
MAV_1761|M.avium_104                YAVFLISRYHDFLRRG----DDFDQAVRKALISIGKVITASASTVGITFL
Mb1549c|M.bovis_AF2122/97           YAVFLISRYHDYVRHG----EKSDMAVKKALMSIGKVITASAATVAVTFL
Rv1522c|M.tuberculosis_H37Rv        YAVFLISRYHDYVRHG----EKSDMAVKKALMSIGKVITASAATVAVTFL
MUL_0757|M.ulcerans_Agy99           YAIFLIGRYQEARGLG----QDRESAYYTMFGGTAHVVLGSGLTIAGATF
                                    *::**:.**::              :        .:*: .*. *:. : :

MMAR_4836|M.marinum_M               AMVFAKLSVFAALGPACAIAVFVGFAATVTLFPPVLALAAKRG-IGEPKA
TH_3450|M.thermoresistible__bu      AMVFARLSVFAALGPACAIAVLFGFLATVTLLPPVLALAAKRG-IGDPKP
Mflv_4632|M.gilvum_PYR-GCK          AMVFARLSVFAALGPACAIAVLFGFLATVTLLPPVLSLAAKRG-IGEPKP
Mvan_0312|M.vanbaalenii_PYR-1       AMVFARLSVFAALGPACAIAVLFGFLATVTLLPPVLSLAAERG-IGEPKS
MAB_0855|M.abscessus_ATCC_1997      GMGFTKLGILSTVGPALSVSILIAFVASVTFLPAVLVLVGRRG-WITPRK
MSMEG_4741|M.smegmatis_MC2_155      GLAFTDLGVFSTVGPALSVTIGFGFVASVTLLPAMVVLAGRRG-WVKPRK
MLBr_01231|M.leprae_Br4923          GMSFTKIRVFSTVGPALAIGIAVAFLAAVTLMPALLVLAGTRG-WVAPRR
MAV_1761|M.avium_104                LIGFARMGVFKTVGISSAIGIGVAFLAAVTLLPAIMVLAGPRG-WIRPRR
Mb1549c|M.bovis_AF2122/97           AMVFTKLEVFSAVGPAIAVAITVSLLGAVTLLPAILTLTGRRG-WIKPRR
Rv1522c|M.tuberculosis_H37Rv        AMVFTKLEVFSAVGPAIAVAITVSLLGAVTLLPAILTLTGRRG-WIKPRR
MUL_0757|M.ulcerans_Agy99           CLSFTRLPYFQTLGVPLAIGMVIVVATALTLGPALIAVMSRFGKLLEPKR
                                     : *: :  : ::* . :: : . .  ::*: *.:: : .  *    *: 

MMAR_4836|M.marinum_M               DRTRRYWNWIAVAVVRRPVPLLVASLALVLGLAAVALTMHISYDDRRGQP
TH_3450|M.thermoresistible__bu      DRTRRYWNSVAVAVVRRPVTLLTISLAVLLALSAVAVTINISYDDRKGQP
Mflv_4632|M.gilvum_PYR-GCK          DRTRRYWNSVAVAVVRRPVPLLIVSLVILLALSAAAATIKISYDDRKGQP
Mvan_0312|M.vanbaalenii_PYR-1       DRTRRYWNSVAVAVVRRPVPLLIVSLVILLALSAAAATIKISYDDRKGQP
MAB_0855|M.abscessus_ATCC_1997      AYANKIWHRSGINIVKRPGAHLAVSLVVLVILATCGAMVKFGYDDRKNLP
MSMEG_4741|M.smegmatis_MC2_155      DLTGRIWRRSGVHIVRKPVIHLVASLTVLLALAGCAMLVNFNYDDRKNLP
MLBr_01231|M.leprae_Br4923          DRAGAFWRRTGVRIVRRPVAYLSASMVILIVLALCASLVRFNYDDRKQIP
MAV_1761|M.avium_104                ELTTGLWRRSGIRIVRRPRAHLVASVLVLIILASCAGLVRYNYDDRKALR
Mb1549c|M.bovis_AF2122/97           DLTSRMWRRSGVRIVRRPTIHLVGSLIVLVALAGCTLLIRFNYDDLKTVP
Rv1522c|M.tuberculosis_H37Rv        DLTSRMWRRSGVRIVRRSTIHLVGSLIVLVALAGCTLLIRFNYDDLKTVP
MUL_0757|M.ulcerans_Agy99           MARVRGWRKIGAAIVRWPGPILIGAVALALVGLLTLPGYKTNYNDRNYLP
                                          *.  .  :*: .   *  :: : :         . .*:* .   

MMAR_4836|M.marinum_M               ATTASNEGYRLLDRHFRKDAIVTEFMVVESPTDMRTSKALADLDEMASRV
TH_3450|M.thermoresistible__bu      ADTASNQGYQLLDRHFRKDVVFTEFLVVENPTDMRTGKGLADLDEMASRV
Mflv_4632|M.gilvum_PYR-GCK          DTTASNQGYHLLDRHFRKDVVISEFLVVENPTDMRTGKGLADLDEMASRV
Mvan_0312|M.vanbaalenii_PYR-1       ATTASNQGYHLLDRHFRKDVVITEFLVVENPTDMRTGKGLADLDEMASRV
MAB_0855|M.abscessus_ATCC_1997      PWADSNQGYAAIEKHFPVNSTLPQYLYIKSPHDLRTPRGLADLEQMAARV
MSMEG_4741|M.smegmatis_MC2_155      DDAHSNMGYAALDKHFPVSSTVQQFILIQSPHDLRSPKALADMEQMAQRV
MLBr_01231|M.leprae_Br4923          ASDESSVGYAALESHFPVGQAIPEYLLIQSPHDLRTPRALADMAELAQRV
MAV_1761|M.avium_104                PSAPSSVGYAALERHFPVNQSIPEYILIRSPHDLRTPQALADLEQLADRV
Mb1549c|M.bovis_AF2122/97           QHVESVKGYEAMNRHFPMNAMTPMVLFIKSPRDLRTPGALADIEMMSREI
Rv1522c|M.tuberculosis_H37Rv        QHVESVKGYEAMNRHFPMNAMTPMVLFIKSPRDLRTPGALADIEMMSREI
MUL_0757|M.ulcerans_Agy99           ADLPANEGYSAAERHFSQARMNPEVLMVESDHDMRNSSDFLVINKIAKAI
                                        :  **   : **         : :..  *:*.   :  :  ::  :

MMAR_4836|M.marinum_M               SQLPGVTKVSGVTRPTGARLDQAQLSWQNGEIGDKMAGAVAKGDAHKDDL
TH_3450|M.thermoresistible__bu      AQIPGVTKVSGVTRPTGERLDQAKLAWQNQQIGDKMADAVADGNARKADL
Mflv_4632|M.gilvum_PYR-GCK          SQIPGVTKVSGVTRPTGERLDQAELAWQNGQIGDKMAGAVAEGNSRKDDL
Mvan_0312|M.vanbaalenii_PYR-1       SQIPGVTKVSGVTRPTGERLDQAELAWQNGQIGDKMAGAVAEGNSRKDDL
MAB_0855|M.abscessus_ATCC_1997      SQVPGVDKVRGITRPTGEPLEEAKLSYQAGEVGGKLGDASNLIDARTRDL
MSMEG_4741|M.smegmatis_MC2_155      SQLPDIEMVRGVTRPTGEMLQEARATWQAGEVGGKLNDASTLIDANDANL
MLBr_01231|M.leprae_Br4923          SQIPGIALVRGVTRPTGKPLEETSATYQAGMVGKQLGSASHLIGESTGDL
MAV_1761|M.avium_104                SQLPNVSVVSGITRPTGNVPEQFRATYQAGAIGSMLAGGSTMINDQTDDL
Mb1549c|M.bovis_AF2122/97           AELPNIVMVRGLTRPNGEPLKETKVSFQAGEVGGKLDEATTLLEEHGGEL
Rv1522c|M.tuberculosis_H37Rv        AELPNIVMVRGLTRPNGEPLKETKVSFQAGEVGGKLDEATTLLEEHGGEL
MUL_0757|M.ulcerans_Agy99           FGVEGISRVQAITRPDGKPIEHTSIPFLISMQGTSQKLTEKYNQDLTTSM
                                      : .:  * .:*** *   ..   .:     *               .:

MMAR_4836|M.marinum_M               AKLTHGADQLAGGLAQLDTTLRTALTPLTGLLTQAQSSGSQVQRFRPLLQ
TH_3450|M.thermoresistible__bu      AKLTNGADQLAAGLAQLDTTLRTALAPLSGILSQAQSAGTQMQQFRPLLQ
Mflv_4632|M.gilvum_PYR-GCK          AKLTGGADQLADGLAQLDSTVRTALTPLAGILTQAQSAGTQVNQFRPGLL
Mvan_0312|M.vanbaalenii_PYR-1       AKLTGGADQLADGLAQLDSTVRTALTPLAEILTQAQSAGTQVNQFRPLLQ
MAB_0855|M.abscessus_ATCC_1997      DKLAAGGHTLADKLGQVRDSVKNSLGTARALVEVLAQLRGS-GRTGT-LA
MSMEG_4741|M.smegmatis_MC2_155      STLSGGAHKLADVLGQISTQVTNALVTVRPLAGALADMETKYGGEKT-LD
MLBr_01231|M.leprae_Br4923          NRLASGAGLLADKLGDVRIQVGQAVAGISGLLDNLAFAQKMFGDSKT-LG
MAV_1761|M.avium_104                NRLARGAGTLADNLGDVRGQVNQLAASVRELENAFSSTKNQYSGDAL-VN
Mb1549c|M.bovis_AF2122/97           DQLTGGAHQLADALAQIRNEINGAVASSSGIVNTLQAMMDLMGGDKT-IR
Rv1522c|M.tuberculosis_H37Rv        DQLTGGAHQLADALAQIRNEINGAVASSSGIVNTLQAMMDLMGGDKT-IR
MUL_0757|M.ulcerans_Agy99           LQQVNDIQTNIDQMERMHDLTQQMADVTHQMVIQMKGMVVDVEELRNHIA
                                         .       :  :             :                 : 

MMAR_4836|M.marinum_M               QLSATAPAVDQAIRTGPGLRQQADQAQNAIAAIDPLVGALNTSPWCATTP
TH_3450|M.thermoresistible__bu      QLSATAPAVDQAIQAGPGLRPWADQAAHAIAILDPLVGALNTAPWCATTP
Mflv_4632|M.gilvum_PYR-GCK          RAFRTADFAGIMPR------------------------AVNSCIRCGLHA
Mvan_0312|M.vanbaalenii_PYR-1       QLSATAPAVDQAIQSSPGLRPLANQAQNAISQLDPLVGALNTSPWCATTP
MAB_0855|M.abscessus_ATCC_1997      DLDSVDKLVTSMHSLGDAIEANAQGASEVYGWIEPVARVLVGNPACDMDP
MSMEG_4741|M.smegmatis_MC2_155      QIDQSAELVANMRSLGRAMGVNLARITDVYDWSAPMVRALNVSPECNLDP
MLBr_01231|M.leprae_Br4923          EIDTAGKLVSSMRALGNMFGINFSTTMNDINWVGAVVIALDSSVLCDTNP
MAV_1761|M.avium_104                QVDIAARLVDHVNSLSNAMGWNFTAAKNMFAWIGPVLAALQGNPVCDADS
Mb1549c|M.bovis_AF2122/97           QLENASQYVGRMRALGDNLSGTVTDAEQIATWASPMVNALNSSPVCNSDP
Rv1522c|M.tuberculosis_H37Rv        QLENASQYVGRMRALGDNLSGTVTDAEQIATWASPMVNALNSSPVCNSDP
MUL_0757|M.ulcerans_Agy99           DFDDFFRPIR---------------------------SYFYWEKHCFDIP
                                                                           .     *   .

MMAR_4836|M.marinum_M               ECTQLRDQVQILVTLRHTGFFNQLANLGDLYQPGS--DTAAGTVADVQNT
TH_3450|M.thermoresistible__bu      QCAQIRDQVQVLVTLRNSGFFNQVADLGDRYNPATG-ATVAETLADIRNA
Mflv_4632|M.gilvum_PYR-GCK          ACG-----------------------------SPTR-SEVCADYRTVR--
Mvan_0312|M.vanbaalenii_PYR-1       QCAQIRDQVKILVTLRDSGFFTQIADLGDRYDPATN-ATVGGTLANVQNA
MAB_0855|M.abscessus_ATCC_1997      GCRSSRDEMNKFLETKQDGTRDKIVELGRELKSVDNDKQISSTIARLRTA
MSMEG_4741|M.smegmatis_MC2_155      ACAASRSDLQRIVEAKDNGNLDKFAELGRQLESTEGDETLDEAVSGLQQS
MLBr_01231|M.leprae_Br4923          ICADARAQFHKLLTASEDGTLDNIAHLWKQLGSTQSSQTIGATVSGLEKT
MAV_1761|M.avium_104                SCSATRATFEQLVGPRGQADLDAIDDLSHQLQAYPDKRALKASTDRLRNA
Mb1549c|M.bovis_AF2122/97           ACRTSRAQLAAIVQAQDDGLLRSIRALAVTLQQTQEYQTLARTVSTLDGQ
Rv1522c|M.tuberculosis_H37Rv        ACRTSRAQLAAIVQAQDDGLLRSIRALAVTLQQTQEYQTLARTVSTLDGQ
MUL_0757|M.ulcerans_Agy99           VCWSLRS----------------------VFDTLDGVDLMTEDINNLLPL
                                     *                                            :   

MMAR_4836|M.marinum_M               ITSLDKTFGALG--DPADLAGNIRRLQSGISQLASGAQALATGVHTLADS
TH_3450|M.thermoresistible__bu      VTAMDKAFGALG--DPADLAGNIGRLQDGISQLASGAQALATGVHTLVDS
Mflv_4632|M.gilvum_PYR-GCK          ------------------YSGQYQLLLSSASDTPCGAHVHFSGLQRMILR
Mvan_0312|M.vanbaalenii_PYR-1       VASLDKAFGALG--DPADLATNLRRLQDGIGQLASGAQALATGVRTLADS
MAB_0855|M.abscessus_ATCC_1997      LNSIDTNLRRLGLSDSYGIQKRFTEVLTGVNSLADGSAQLAEGVQMLVDQ
MSMEG_4741|M.smegmatis_MC2_155      IKEATAAARELGLEDASSVKRQLDQLEQGVNLLADSSHQLAQGVQLLVDQ
MLBr_01231|M.leprae_Br4923          LTAVNTSLRSLGLDNPNVMRSKMIGLQNGVNDLASAGRRIADGVAVLVDQ
MAV_1761|M.avium_104                FAKLNDVLRAMGMDRPGGLQSNLTTLQNGADQFAGGSRQVADAVAQLVDK
Mb1549c|M.bovis_AF2122/97           LKQVVSTLKAV-----DGLPTKLAQMQQGANALADGSAALAAGVQELVDQ
Rv1522c|M.tuberculosis_H37Rv        LKQVVSTLKAV-----DGLPTKLAQMQQGANALADGSAALAAGVQELVDQ
MUL_0757|M.ulcerans_Agy99           MERLDTLMPQMT--------AMMPEMIQTMKSMKAQMLSMHSTQQGLQDQ
                                                             :                    :   

MMAR_4836|M.marinum_M               NIEMLSGMSQIATQLQNSARTTAGSDNASGFYLPTNAFENRQFADVAKHF
TH_3450|M.thermoresistible__bu      NLEMLSGMSQIATQLQNSARASADSDSSSGFYLPPNTFENRQFADVAKQF
Mflv_4632|M.gilvum_PYR-GCK          ------------ARYPNIFRSAPARLS----------YQGRRF-------
Mvan_0312|M.vanbaalenii_PYR-1       NIEMLSGMSQIATQLQNSSRAAADSDSSSGFYLPANAFENRQFTDVAEQF
MAB_0855|M.abscessus_ATCC_1997      TKQMGGQLGDASTLLVAAKRDAA-PGSMSGFYIPQQVLTQDSFKTAAAAF
MSMEG_4741|M.smegmatis_MC2_155      TRNMGQGLDQASQFLLAMKRDAS-DPQMSGFYIPPQILTQEEFNKAAALF
MLBr_01231|M.leprae_Br4923          TRTMGTSLARASAFLMEMGQDAS-QPSMAGFNVPPQLLNTEDFKKLVQAF
MAV_1761|M.avium_104                VKQLGAGLSESAAFLLSLKHDAA-HPAMAGFNIPAQLLRLPQFQEAAKVF
Mb1549c|M.bovis_AF2122/97           VKKMGSGLNEAADFLLGIKRDAD-KPSMAGFNIPPQIFSRDEFKKGAQIF
Rv1522c|M.tuberculosis_H37Rv        VKKMGSGLNEAADFLLGIKRDAD-KPSMAGFNIPPQIFSRDEFKKGAQIF
MUL_0757|M.ulcerans_Agy99           MAAMQEDSSAMGEAFDSSRNDDS-------FYLPPEVFNNPDFKRGLEQF
                                                       .                      *       

MMAR_4836|M.marinum_M               LSPDGKTARFAIESSYDPYSSDAMNLAHKITEVADAARPNTSLANATVSM
TH_3450|M.thermoresistible__bu      LSPDGKTARFAIESSHDPYSVDAMNLAHTITDVADAARPNTSLAHATVSV
Mflv_4632|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_0312|M.vanbaalenii_PYR-1       LSPDGKTARFMIESSHDPYSVEAMDLASRITDTANTARPNTSLADATVSV
MAB_0855|M.abscessus_ATCC_1997      VSADGHAVRYLVQSNLNPFSPEAMDQVRAIQEAARSAQPNTTLSDASISM
MSMEG_4741|M.smegmatis_MC2_155      VSPDGRSVRYLVQTALDPFGTAAMDQVKDIVKTAESARPNTSLTDAKISL
MLBr_01231|M.leprae_Br4923          ISPDGHSVRYFIQTDLNPFSSAAMDQVNTILNVATGAQPNTTLSDASIYL
MAV_1761|M.avium_104                ISPDGHSVRYLVQSKLSPFSTQAMDQVDAITATARGAQPNTALADAEVSM
Mb1549c|M.bovis_AF2122/97           LSADGHAARYFVQSALNPATTEAMDQVNDILRVADSARPNTELEDATIGL
Rv1522c|M.tuberculosis_H37Rv        LSADGHAARYFVQSALNPATTEAMDQVNDILRVADSARPNTELEDATIGL
MUL_0757|M.ulcerans_Agy99           LSPDGHAVRFIISHEGDPMSQAGINHIDKIKTAAKEAIKGTPLEGSTIYL
                                                                                      

MMAR_4836|M.marinum_M               AGFPAVNSDIQRLLSADFHQLAFATLVIVGLILVVLLRALVAPLYLLGTV
TH_3450|M.thermoresistible__bu      AGFPAVNSDIARLLWADFAQLAIATIVIVGLILVLLLRALLAPIYLLGTV
Mflv_4632|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_0312|M.vanbaalenii_PYR-1       AGFPAVNSDIQRLLWADFAQLAIATIIIVGVILVLLLRALLAPLYLLGTV
MAB_0855|M.abscessus_ATCC_1997      AGLSAMYNDIRNYYNHDLRFIIVLTVIVVLLILVALLRAIVAPLYLIGSV
MSMEG_4741|M.smegmatis_MC2_155      VGFSSIQNEMRNYYDGDLRFIITVTLIVVFLILAALLRSIIAPIYLVLSV
MLBr_01231|M.leprae_Br4923          SGYTVTLRDTRDYYDRDLQLIVIVTMIVVLLILMALLRSIVAPIYLVGSV
MAV_1761|M.avium_104                AGYTVGLKDTRDYYQHDIKFIIAVTLLVVLLTLMALLRAIVAPLYLVATV
Mb1549c|M.bovis_AF2122/97           AGVPTALRDIRDYYNSDMKFIVIATIVIVFLILVILLRALVAPIYLIGSV
Rv1522c|M.tuberculosis_H37Rv        AGVPTALRDIRDYYNSDMKFIVIATIVIVFLILVILLRALVAPIYLIGSV
MUL_0757|M.ulcerans_Agy99           GGTVAMFKDLSDGNTFDLMIAGISALCLIFIIMLIITRSVVAAAVIVGTV
                                                                                      

MMAR_4836|M.marinum_M               VLNYGAALGLGTLVFQYGLGKEIAWPVPLLAFIILVAVGADYNMLLISRL
TH_3450|M.thermoresistible__bu      VLNYLASLGIGVLVFQYLLGHEIAWPVPLLAFIILVAVGADYNMLLVSRL
Mflv_4632|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_0312|M.vanbaalenii_PYR-1       VLNYLASLGIGVVVFQWGLGHEIAWPVPLLAFIILVAVGADYNMLLVSRL
MAB_0855|M.abscessus_ATCC_1997      IISYASAVGIGVIAFQFIGGQPLSWSVPGMAFIVLVAVGADYNLLFISRI
MSMEG_4741|M.smegmatis_MC2_155      VLSYMSALGIGVVFFQFILGKEIVWTVPGMAFLVLVAVGADYNLLLISRI
MLBr_01231|M.leprae_Br4923          IVSYLSALGLCVLVFQVLLRQQLHWSVPGLAFVVLVAVGADYNMLLASRL
MAV_1761|M.avium_104                VISYLSAVGVGVLVFQFLLGQQLHWSVPPLAFVVLVAVGADYNMLLVSRM
Mb1549c|M.bovis_AF2122/97           LISYLSALGIGTLVFQLILGQEMHWSLPGLSFILLVAIGADYNMLLISRI
Rv1522c|M.tuberculosis_H37Rv        LISYLSALGIGTLVFQLILGQEMHWSLPGLSFILLVAIGADYNMLLISRI
MUL_0757|M.ulcerans_Agy99           VLSLGASFGLSVLIWQHVLGIELHWLVLAMAVIILLAVGADYNLLLVARL
                                                                                      

MMAR_4836|M.marinum_M               REESAHNIRVGVLRTVANTGSVITSAGLIFAASMFGLIAGSIAIMIQAGF
TH_3450|M.thermoresistible__bu      REESGTNIRVGVLRTVANTGSVITSAGVIFAASMFGLMFGSIAIMIQAGF
Mflv_4632|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_0312|M.vanbaalenii_PYR-1       REESGTNIRVGVLRTVANTGAVITSAGLIFAASMFGLMVGSVAIMIQAGL
MAB_0855|M.abscessus_ATCC_1997      RDESPDGIRSGVIKTVKSTGGVITSAGVIFAASMFGLLIGNLQSMVEAGF
MSMEG_4741|M.smegmatis_MC2_155      RDEAAHGMRTAVIRTIGATGGVITSAGLIFAASMFGLTFSSLLAAVQIGF
MLBr_01231|M.leprae_Br4923          RDESSHGLRASVIRTVRSTGGVITAAGLIFAASMFGLLLSSIATVVQAGF
MAV_1761|M.avium_104                RDESPHSMRYGIIRTLSSTGGVITAAGLIFAASMSGLLFSSIGTVVQGGV
Mb1549c|M.bovis_AF2122/97           RDESPHGIRIGVIRTVGSTGGVITSAGLIFAASMFGLVGANINTMAQAGF
Rv1522c|M.tuberculosis_H37Rv        RDESPHGIRIGVIRTVGSTGGVITSAGLIFAASMFGLVGASINTMAQAGF
MUL_0757|M.ulcerans_Agy99           KEEIHAGINTGIIRAMGGSGSVVTAAGLVFAFTMMSFAVSELTVMAQVGT
                                                                                      

MMAR_4836|M.marinum_M               IIGCGLLLDTFVVRTLTVPAIATLLREASWWP------------------
TH_3450|M.thermoresistible__bu      IVGCGLLLDTFLVRTLTVPAIATLLREASWWP------------------
Mflv_4632|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_0312|M.vanbaalenii_PYR-1       IIGFGLLLDTFLVRTLTVPAIATLLREASWWP------------------
MAB_0855|M.abscessus_ATCC_1997      IIGMGLLLDTFLVRTITIPALVVLCGQANWWPSASVES------------
MSMEG_4741|M.smegmatis_MC2_155      IIGVGLLLDTFLVRTITVPAAAVLIGKLSWWP------------------
MLBr_01231|M.leprae_Br4923          VLGSGILLDTFIVRTITVPAVAALLRRASWWP------------------
MAV_1761|M.avium_104                VIGVGILLDTFLVRTVTVPAIAALAGRANWWP------------------
Mb1549c|M.bovis_AF2122/97           TIGIGIVLDTFLVRTVTVPALTTMIGRANWWPSELGRDPSTPPTKADRWL
Rv1522c|M.tuberculosis_H37Rv        TIGIGIVLDTFLVRTVTVPALTTMIGRANWWPSELGRDPSTPPTKADRWL
MUL_0757|M.ulcerans_Agy99           TIGMGLLFDTLIVRSFMTPSIAALLGKWFWWPQVVRQRP-----------
                                                                                      

MMAR_4836|M.marinum_M               -----------------------------QRKPLTHNG------------
TH_3450|M.thermoresistible__bu      -----------------------------QPNRAR---------------
Mflv_4632|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_0312|M.vanbaalenii_PYR-1       -----------------------------TKATNPRRGDPKQKA------
MAB_0855|M.abscessus_ATCC_1997      WFRQRFSRSKPDAQEGDCAVSDDPEAASGESSPEEPLISASREVELAGRR
MSMEG_4741|M.smegmatis_MC2_155      --------TKPPAP---------------EPAPTEPTVAPAAQA------
MLBr_01231|M.leprae_Br4923          ------------------------------ARPWGNNA------------
MAV_1761|M.avium_104                ------------------------------SRIAVRRNPVSGQP------
Mb1549c|M.bovis_AF2122/97           RRVKGHRRKAPIPAPKPPHTKVVRNTNGHASKAATKSVPNGKPADLAEGN
Rv1522c|M.tuberculosis_H37Rv        RRVKGHRRKAPIPAPKPPHTKVVRNTNGHASKAATKSVPNGKPADLAEGN
MUL_0757|M.ulcerans_Agy99           -----------------------------APQPWPTPAPTPPPATTSV--
                                                                                      

MMAR_4836|M.marinum_M               --------------------------------------------------
TH_3450|M.thermoresistible__bu      --------------------------------------------------
Mflv_4632|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_0312|M.vanbaalenii_PYR-1       --------------------------------------------------
MAB_0855|M.abscessus_ATCC_1997      --------------------------------------------------
MSMEG_4741|M.smegmatis_MC2_155      --------------------------------------------------
MLBr_01231|M.leprae_Br4923          --------------------------------------------------
MAV_1761|M.avium_104                --------------------------------------------------
Mb1549c|M.bovis_AF2122/97           GEYLIDHLRRHSLPLFGYAAMPAYDVVDGVSKPNGDGAHIGKEPVDHLLG
Rv1522c|M.tuberculosis_H37Rv        GEYLIDHLRRHSLPLFGYAAMPAYDVVDGVSKPNGDGAHIGKEPVDHLLG
MUL_0757|M.ulcerans_Agy99           --------------------------------------------------
                                                                                      

MMAR_4836|M.marinum_M               ----------------------------------------
TH_3450|M.thermoresistible__bu      ----------------------------------------
Mflv_4632|M.gilvum_PYR-GCK          ----------------------------------------
Mvan_0312|M.vanbaalenii_PYR-1       ----------------------------------------
MAB_0855|M.abscessus_ATCC_1997      ----------------------------------------
MSMEG_4741|M.smegmatis_MC2_155      ----------------------------------------
MLBr_01231|M.leprae_Br4923          ----------------------------------------
MAV_1761|M.avium_104                ----------------------------------------
Mb1549c|M.bovis_AF2122/97           H---------------------------------------
Rv1522c|M.tuberculosis_H37Rv        HSLPLFGLAGLPSYDRWDDTSIGEPAVGHAGSKPDAKLST
MUL_0757|M.ulcerans_Agy99           ----------------------------------------