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aa seq not available
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. thermoresistible (build 8) | TH_2203 | mmpL8 | - | 100% (1001) | PROBABLE CONSERVED INTEGRAL MEMBRANE TRANSPORT PROTEIN MMPL8 |
M. thermoresistible (build 8) | TH_3450 | - | 0.0 | 42.02% (978) | PUTATIVE MMPL domain protein |
M. thermoresistible (build 8) | TH_3260 | - | e-129 | 30.43% (989) | PUTATIVE MmpL4 protein |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb3853c | mmpL8 | 0.0 | 55.79% (1011) | integral membrane transport protein |
M. gilvum PYR-GCK | Mflv_0403 | - | 0.0 | 54.20% (987) | transport protein |
M. tuberculosis H37Rv | Rv3823c | mmpL8 | 0.0 | 55.69% (1011) | integral membrane transport protein |
M. leprae Br4923 | MLBr_01231 | mmpL10 | 0.0 | 54.03% (979) | hypothetical protein MLBr_01231 |
M. abscessus ATCC 19977 | MAB_0855 | - | 0.0 | 55.59% (984) | MmpL family protein |
M. marinum M | MMAR_2342 | - | 0.0 | 56.51% (1014) | MmpL family transport protein |
M. avium 104 | MAV_1761 | - | 0.0 | 54.80% (989) | MmpL10 protein |
M. smegmatis MC2 155 | MSMEG_4741 | - | 0.0 | 54.26% (986) | MmpL protein |
M. ulcerans Agy99 | MUL_0757 | mmpL5 | 1e-115 | 28.46% (1005) | transmembrane transport protein, MmpL5 |
M. vanbaalenii PYR-1 | Mvan_0271 | - | 0.0 | 53.56% (982) | transport protein |
CLUSTAL 2.0.9 multiple sequence alignment TH_2203|M.thermoresistible__bu -------------------MGGTETPTGRGFFGRLGDFVIRFPLIVIGLW MMAR_2342|M.marinum_M -------------------MSDSEAARAGGFFDKLSRFVIQKPFVVIAIW MAB_0855|M.abscessus_ATCC_1997 -----------------------MAENTGGIYGLIAQIVRRAPVIVIGLW MSMEG_4741|M.smegmatis_MC2_155 -------------------------MSRVGFSGLGRFIVR-HPLVVIASW Mb3853c|M.bovis_AF2122/97 MCDVLMQPVRTPRPSTNLRSKPLRPTGDGGVFPRLGRLIVRRPWVVIAFW Rv3823c|M.tuberculosis_H37Rv MCDVLMQPVRTPRPSTNLRSKPLRPTGDGGVFPRLGRLIVRRPWVVIAFW MLBr_01231|M.leprae_Br4923 --------------------------------------------MVIGCW Mflv_0403|M.gilvum_PYR-GCK -------------------------------MRRLADVVVRWPWAVIGVW Mvan_0271|M.vanbaalenii_PYR-1 -------------------------------MRRLADLVVRWPWAVIAVW MAV_1761|M.avium_104 -------------------MSPTAPAGDEVEMRRIADFVVRWPWLVIGFW MUL_0757|M.ulcerans_Agy99 -----------MTATTTDTPTDVVPPAEHPPRPFIPRMIRTFAVPLILGW :* * TH_2203|M.thermoresistible__bu VGLAVVLVATVPPLAEVAAR-NPVSVLPEDAPVMVTSREMSEAFD----- MMAR_2342|M.marinum_M ISLAAIPALMFPPLMEAAAGKNNSAALPDDAPTMVASKEMAKTFEGKSNK MAB_0855|M.abscessus_ATCC_1997 IGLAAVLALTAPSLQKAIED-HPVDLLPKDAPVMETTRQMVESFQ----- MSMEG_4741|M.smegmatis_MC2_155 LAVAGVLLAAVPSLPAVAER-NPPGFLPADSEVFAAGNAMQEAFN----- Mb3853c|M.bovis_AF2122/97 VALAGLLAPTVPSLDAISQR-HPVAILPSDAPVLVSTRQMTAAFR----- Rv3823c|M.tuberculosis_H37Rv VALAGLLAPTVPSLDAISQR-HPVAILPSDAPVLVSTRQMTAAFR----- MLBr_01231|M.leprae_Br4923 TLLALMLPMTVPSLTELTQR-HPVVILPVDAPSSVAAKKISQAFH----- Mflv_0403|M.gilvum_PYR-GCK IALAVALPLSFPSLGQMAAK-NPLQILPADAPSSVTAQKMAEAFD----- Mvan_0271|M.vanbaalenii_PYR-1 VAMAVALPLSFPSLGEMAQK-HPLVILPSDAPSSVTAAKMAEAFQ----- MAV_1761|M.avium_104 AALAVALPLAFPSLAEMAQK-HPLAILPGNAPSNVAARQMTEAFH----- MUL_0757|M.ulcerans_Agy99 VLLIAVLNSVVPQLEVVGQM-QAVSMSPDAAPSMISMKHIGKVFR----- : * * : * : : : * TH_2203|M.thermoresistible__bu -------------DSGGDNLLLVVMTDEEGLGPEDEKAYQKLVAALRAEP MMAR_2342|M.marinum_M KDAKAKPGSKPKEDPSDGSQLLVILTDENGLGPGDLAAYTKLVEKLRAEK MAB_0855|M.abscessus_ATCC_1997 -------------ESGAQNILLIVLTNENGLTPADEQTYRILAARMREDT MSMEG_4741|M.smegmatis_MC2_155 -------------ETGGGNVAIAILSNENGLTPADEETYRALVDKLRADT Mb3853c|M.bovis_AF2122/97 -------------EAGLQSVAVVVLSDAKGLGAADERSYKELVDALRRDT Rv3823c|M.tuberculosis_H37Rv -------------EAGLQSVAVVVLSDAKGLGAADERSYKELVDALRRDT MLBr_01231|M.leprae_Br4923 -------------EVDSENVLIVLLTDDKGLGPADETVYRTLVDRLRNDT Mflv_0403|M.gilvum_PYR-GCK -------------EPGSDNLLVVAFINESGLVPEDELTYRNVVDALRDDV Mvan_0271|M.vanbaalenii_PYR-1 -------------ETSNDNLLLVAFINETGLEPADEATYRKVVDALRDDV MAV_1761|M.avium_104 -------------ESGSDDLLLVALTDEKGLGPADEAVYRRLVDALRRDT MUL_0757|M.ulcerans_Agy99 -------------EGDSDSAAMIVLEGQEPLGAAAHKFYDKMITKLRADT : . . : : . * . * : :* : TH_2203|M.thermoresistible__bu NGDIMMMQDFITTPQLREVVASEDGKAWYLPINLAGAWSTPEGGGAFTRV MMAR_2342|M.marinum_M YS----VQDFISNPPLREVLASKDNKAWNLPVMFKTSQDDPATQSAYKKI MAB_0855|M.abscessus_ATCC_1997 RD-VSMVQDFITKPPLREMMSSTDGKAWYLPVGLQGELATPESGKAYVGA MSMEG_4741|M.smegmatis_MC2_155 EY-VLSTQDFVTIPELRQVMTSEDNKAWQLPISAAGTMGTAEGQNAYRQI Mb3853c|M.bovis_AF2122/97 RD-VVMLQDFVTTPPLRELMTSKDNQAWILPVGLPGDLGSTQSKQAYARV Rv3823c|M.tuberculosis_H37Rv RD-VVMLQDFVTTPPLRELMTSKDNQAWILPVGLPGDLGSTQSKQAYARV MLBr_01231|M.leprae_Br4923 KD-VVVLQDFLSTPPLHELLVSKDGKAWILPIVLAGELGTSASYQAYAGV Mflv_0403|M.gilvum_PYR-GCK AD-VVSVQDFLGTPQLRQFLTSEDKTTWVLPVSLVGELGTPRAYESFNRV Mvan_0271|M.vanbaalenii_PYR-1 TD-VVSVQDFVSTPQLRQFLTSEDKTTWVLPVSLEGELGTPRAFDSFNRV MAV_1761|M.avium_104 RD-VVMVQDFISAPPLRSAVTSKDRKAWVLPVGIAGELGTPQSYAAFNRI MUL_0757|M.ulcerans_Agy99 KH-VQSVQDFWGDPLTATGAQSGDGKAAYVQVKLAGNQGESLANESVEAV *** * * * : : : . : TH_2203|M.thermoresistible__bu AEIVREATADA-------PMTVHLTGPAATIADVTAVGQRDIHVIEIATV MMAR_2342|M.marinum_M KELVKEALAGS-------TLTAHYAGAVATVADLVTIGQEDTHIIEIGTA MAB_0855|M.abscessus_ATCC_1997 LKIIKDATQGT-------SLKAFTTGPTATVGDLTVVGERDLHKVEITTA MSMEG_4741|M.smegmatis_MC2_155 VDTVKSSTANT-------SLSAEVIGPAATFEDVVKIGERDQHVIEIATV Mb3853c|M.bovis_AF2122/97 ADIVEH---QVAGS----TLTANLTGPAATVADLNLTGQRDRSRIEFAIT Rv3823c|M.tuberculosis_H37Rv ADIVEH---QVAGS----TLTANLTGPAATVADLNLTGQRDRSRIEFAIT MLBr_01231|M.leprae_Br4923 AGIVKQTLESTAGS----SLKANLTGPASTVADLTDAGARDRTSIELVIA Mflv_0403|M.gilvum_PYR-GCK ADVIRHEVPDAGTG--GSSLTVHVTGPAATVADLTVAGEQDRLPIEIAIA Mvan_0271|M.vanbaalenii_PYR-1 SDVVKHHLGDG-------PLQVYLTGPAATVADLTVAGEQDRLPIEIAIA MAV_1761|M.avium_104 AGIVKQTLEKHENGPAATSLTVSLTGPAATVADLTVAGERDRLPIELAIA MUL_0757|M.ulcerans_Agy99 KTIVDSLQAPP-------GVKVYVTGSAALVADQQLAGDRSLQLIEMVTF : : . *..: . * * .. :*: TH_2203|M.thermoresistible__bu VMVLTILLIVYRNVVTMLMPLVTIGVAFVTAQGLVGALAPLGLG-VSDQT MMAR_2342|M.marinum_M VSVLVILLMVYRNIVTMLVPLATIGLSLATAQGVLSGLSKIGLD-VQMQT MAB_0855|M.abscessus_ATCC_1997 ALVLLILLIVYRNPVTMMLPLIVVGVSLGIAQAAVGGLAQMGLS-ISNQT MSMEG_4741|M.smegmatis_MC2_155 LIVLMILIIVYRNLVAMLLPLLMIGMALVVAEQSVAGLGAIHLIGLGPQT Mb3853c|M.bovis_AF2122/97 ILLLVILLIIYRNPITMVLPLITIGMSVVVAQRLVA-IAGLAGLGIANQS Rv3823c|M.tuberculosis_H37Rv ILLLVILLIIYGNPITMVLPLITIGMSVVVAQRLVA-IAGLAGLGIANQS MLBr_01231|M.leprae_Br4923 VLLLTILMIIYRNPITMLLPLITIGASLMTAQAVVSGVSVLAGLAVSNQM Mflv_0403|M.gilvum_PYR-GCK VLVLGVLLLVYRNPVTMLLPLLTIGASVLIAQGVVAGYSELTGAGVSNQS Mvan_0271|M.vanbaalenii_PYR-1 VLVLGVLLLVYRSAVTMLLPLVTIGSSLVIAQAVVAGYSQLSGSGVSNQS MAV_1761|M.avium_104 VLVLVVLLVVYRSAVTMLLPLVTILLSLVIAQAAVAGYSQLTGSGVSNQS MUL_0757|M.ulcerans_Agy99 TVIIVMLLLVYRSIITAAIMLTMVVLGLLATRGGVAFLGYHRIIGLSTFA :: :*:::* . :: : * : .. :. :. . : TH_2203|M.thermoresistible__bu IVLMTGIMVGAGVDYAVFLISRYHDFVRRGVEHRA----AIRQAMGSIGK MMAR_2342|M.marinum_M IVFMTAVMIGAGTDYAVFLISRYHDYVRKGQDSDL----AVKNAMMSIGK MAB_0855|M.abscessus_ATCC_1997 LTFMTAMMMGAGVDYAVFLISRYHEYIKQGLASDD----AVAAALESIGK MSMEG_4741|M.smegmatis_MC2_155 LMLMTAMMMGAGTDYAIFLFSRYHECVRSGLSSDD----AVVEALDSIGK Mb3853c|M.bovis_AF2122/97 IIFMSGMMVGAGTDYAVFLISRYHDYLRQGADSDQ----AVKKALTSIGK Rv3823c|M.tuberculosis_H37Rv IIFMSGMMVGAGTDYAVFLISRYHDYLRQGADSDQ----AVKKALTSIGK MLBr_01231|M.leprae_Br4923 IVLLSAMIAGAGTDYAVFLISRYHDYIRMGSGSAQDAGCAVRQALISLGK Mflv_0403|M.gilvum_PYR-GCK IVFLSAILAGAGTDYAVFLISRYHDYLRRGAEAGE----AVRAAMASIGK Mvan_0271|M.vanbaalenii_PYR-1 IVFLSAIMAGAGTDYAVFLISRYHDYLRSGADFDD----AVRAAMISIGK MAV_1761|M.avium_104 IVFLSAIMAGAGTDYAVFLISRYHDFLRRGDDFDQ----AVRKALISIGK MUL_0757|M.ulcerans_Agy99 TNLLVVLAIAAATDYAIFLIGRYQEARGLGQDRES----AYYTMFGGTAH :: : .*..***:**:.**:: * * : . .: TH_2203|M.thermoresistible__bu VIGASAATVAVTFFAMVFTTLSVFQTVGPAMALAIFVCFLAAVTFLPAMI MMAR_2342|M.marinum_M VIAASAATVAVTFLAMVFSKLAIFASIGPAISISIIIAFVAAITLLPSIL MAB_0855|M.abscessus_ATCC_1997 VVAASAATVAVTFLGMGFTKLGILSTVGPALSVSILIAFVASVTFLPAVL MSMEG_4741|M.smegmatis_MC2_155 VIAGSAGTVAITFMGLAFTDLGVFSTVGPALSVTIGFGFVASVTLLPAMV Mb3853c|M.bovis_AF2122/97 VIAASAATVAITFLGMVFTQLGILKTVGPMLGISVAVVFFAAVTLLPALM Rv3823c|M.tuberculosis_H37Rv VIAASAATVAITFLGMVFTQLGILKTVGPMLGISVAVVFFAAVTLLPALM MLBr_01231|M.leprae_Br4923 VIAASAATVGITFLGMSFTKIRVFSTVGPALAIGIAVAFLAAVTLMPALL Mflv_0403|M.gilvum_PYR-GCK VITASASTVGITFLAMSFAEMGVFRTIGVSAAIGIGVAYLAGVTLLPAIL Mvan_0271|M.vanbaalenii_PYR-1 VITASAATVGVTFLVMSFAQMGVFRTIGVSSAIGIGVAFLAGMTLLPAIL MAV_1761|M.avium_104 VITASASTVGITFLLIGFARMGVFKTVGISSAIGIGVAFLAAVTLLPAIM MUL_0757|M.ulcerans_Agy99 VVLGSGLTIAGATFCLSFTRLPYFQTLGVPLAIGMVIVVATALTLGPALI *: .*. *:. : : : *: : : ::* .: : . :.:*: *::: TH_2203|M.thermoresistible__bu VLAGPRG-WISPRRDLTTRFWRRSGIRIVRAPKAHLAVSLIILLGLAGCA MMAR_2342|M.marinum_M VLIGRRG-WIKPRRDLTHRFWRILGTRIVRRPRVHLIGSLIVLAILASST MAB_0855|M.abscessus_ATCC_1997 VLVGRRG-WITPRKAYANKIWHRSGINIVKRPGAHLAVSLVVLVILATCG MSMEG_4741|M.smegmatis_MC2_155 VLAGRRG-WVKPRKDLTGRIWRRSGVHIVRKPVIHLVASLTVLLALAGCA Mb3853c|M.bovis_AF2122/97 VLTGRRG-WIAPRRDLTRRFWRSSGVHIVRRPKTHLLASALVLVILAGCA Rv3823c|M.tuberculosis_H37Rv VLTGRRG-WIAPRRDLTRRFWRSSGVHIVRRPKTHLLASALVLVILAGCA MLBr_01231|M.leprae_Br4923 VLAGTRG-WVAPRRDRAGAFWRRTGVRIVRRPVAYLSASMVILIVLALCA Mflv_0403|M.gilvum_PYR-GCK VLAGPRG-WIKPRRELTAQFWRRSGIRIVRRPVPHLVASALVLALLAGFA Mvan_0271|M.vanbaalenii_PYR-1 VLAGPRG-WVKPRRELTARFWRRSGIRIVRRPVPHLVASVLVLILLAGCA MAV_1761|M.avium_104 VLAGPRG-WIRPRRELTTGLWRRSGIRIVRRPRAHLVASVLVLIILASCA MUL_0757|M.ulcerans_Agy99 AVMSRFGKLLEPKRMARVRGWRKIGAAIVRWPGPILIGAVALALVGLLTL .: . * : *:: *: * **: * * : : TH_2203|M.thermoresistible__bu LTVQFNYDDRKTLPQSVESAAGYAAMERHYPVNSNLPQYLFINSPRDLRS MMAR_2342|M.marinum_M LLVRFNYDDLKALPEDVDSVAGYNAMDRHFPQNMMTPMMLFIKSPHDLRS MAB_0855|M.abscessus_ATCC_1997 AMVKFGYDDRKNLPPWADSNQGYAAIEKHFPVNSTLPQYLYIKSPHDLRT MSMEG_4741|M.smegmatis_MC2_155 MLVNFNYDDRKNLPDDAHSNMGYAALDKHFPVSSTVQQFILIQSPHDLRS Mb3853c|M.bovis_AF2122/97 GLARYNYDDRKTLPASVESSIGYAALDKHFPSNLIIPEYLFIQSSTDLRT Rv3823c|M.tuberculosis_H37Rv GLARYNYDDRKTLPASVESSIGYAALDKHFPSNLIIPEYLFIQSSTDLRT MLBr_01231|M.leprae_Br4923 SLVRFNYDDRKQIPASDESSVGYAALESHFPVGQAIPEYLLIQSPHDLRT Mflv_0403|M.gilvum_PYR-GCK IVADFNYDDRKAVDAAAPSSVGYAALERHFPISQSIPQYILIQSPKDLRN Mvan_0271|M.vanbaalenii_PYR-1 AFATFNYDDRKAVAASAPSSVGYAALERHFPISQSIPQYILVQSPRDLRS MAV_1761|M.avium_104 GLVRYNYDDRKALRPSAPSSVGYAALERHFPVNQSIPEYILIRSPHDLRT MUL_0757|M.ulcerans_Agy99 PGYKTNYNDRNYLPADLPANEGYSAAERHFSQARMNPEVLMVESDHDMRN .*:* : : : ** * : *:. : :.* *:*. TH_2203|M.thermoresistible__bu PEALADLEEMARRVSQLPEVDTVRGITRPTGEPLEQAALSYQAGEVGIRL MMAR_2342|M.marinum_M PTALADLELMVSRVSQLPNIIAIRGLTRPNGEPLEQTKVSYQAGEVGSKL MAB_0855|M.abscessus_ATCC_1997 PRGLADLEQMAARVSQVPGVDKVRGITRPTGEPLEEAKLSYQAGEVGGKL MSMEG_4741|M.smegmatis_MC2_155 PKALADMEQMAQRVSQLPDIEMVRGVTRPTGEMLQEARATWQAGEVGGKL Mb3853c|M.bovis_AF2122/97 PKALADLEQMVQRVSQVPGVAMVRGITRPAGRSLEQARTSWQAGEVGSKL Rv3823c|M.tuberculosis_H37Rv PKALADLEQMVQRVSQVPGVAMVRGITRPAGRSLEQARTSWQAGEVGSKL MLBr_01231|M.leprae_Br4923 PRALADMAELAQRVSQIPGIALVRGVTRPTGKPLEETSATYQAGMVGKQL Mflv_0403|M.gilvum_PYR-GCK PQALADLEQMASRIAQLPDVSLVSGVTRPLGEVPAEFRATFQAGIVGDRL Mvan_0271|M.vanbaalenii_PYR-1 PQALADLEQMASRIAQLPDISLVSGVTRPLGEVPREFRATFQAGLVGDRL MAV_1761|M.avium_104 PQALADLEQLADRVSQLPNVSVVSGITRPTGNVPEQFRATYQAGAIGSML MUL_0757|M.ulcerans_Agy99 SSDFLVINKIAKAIFGVEGISRVQAITRPDGKPIEHTSIPFLISMQGTSQ . : : :. : : : : .:*** *. . .: . * TH_2203|M.thermoresistible__bu DDASKQITDHTGDLDMLADGADQLADALGDVRGQVFQTVATTKALVDALS MMAR_2342|M.marinum_M DEASSAIEDHGGELDQLADGSNQLADALAGVRDEVTESVANAGALVDLLV MAB_0855|M.abscessus_ATCC_1997 GDASNLIDARTRDLDKLAAGGHTLADKLGQVRDSVKNSLGTARALVEVLA MSMEG_4741|M.smegmatis_MC2_155 NDASTLIDANDANLSTLSGGAHKLADVLGQISTQVTNALVTVRPLAGALA Mb3853c|M.bovis_AF2122/97 DEGSKQIAAHTGDIDKLAGGANLMASKLGDVRAQVNRAISTVGGLIDALA Rv3823c|M.tuberculosis_H37Rv DEGSKQIAVHTGDIDKLAGGANLMASKLGDVRAQVNRAISTVGGLIDALA MLBr_01231|M.leprae_Br4923 GSASHLIGESTGDLNRLASGAGLLADKLGDVRIQVGQAVAGISGLLDNLA Mflv_0403|M.gilvum_PYR-GCK AAGSAQIGERSGDLTTLADGATTLADSLGDVRSQVNEIAPSLKGIIDTFS Mvan_0271|M.vanbaalenii_PYR-1 AAGSAQIGARDDDLDELTTGADTLADTLVDVRAQVNKIAPSLQTLLDAVT MAV_1761|M.avium_104 AGGSTMINDQTDDLNRLARGAGTLADNLGDVRGQVNQLAASVRELENAFS MUL_0757|M.ulcerans_Agy99 KLTEKYNQDLTTSMLQQVNDIQTNIDQMERMHDLTQQMADVT-------- . .: . . : : . . TH_2203|M.thermoresistible__bu TLQERFGGDRTLDDIDNAARLVSGMRELGDAIGVNVANVAGNLEWAVPVL MMAR_2342|M.marinum_M TMKKLIGGDKTLNALDQTAKLVGRMRALGDALTSNMVDVSNVVAWVGPIV MAB_0855|M.abscessus_ATCC_1997 QLRGS-GRTGTLADLDSVDKLVTSMHSLGDAIEANAQGASEVYGWIEPVA MSMEG_4741|M.smegmatis_MC2_155 DMETKYGGEKTLDQIDQSAELVANMRSLGRAMGVNLARITDVYDWSAPMV Mb3853c|M.bovis_AF2122/97 YLQDLLGGNRVLGELEGAEKLIGSMRALGDTIDADASFVANNTEWASPVL Rv3823c|M.tuberculosis_H37Rv YLQDLLGGNRVLGELEGAEKLIGSMRALGDTIDADASFVANNTEWASPVL MLBr_01231|M.leprae_Br4923 FAQKMFGDSKTLGEIDTAGKLVSSMRALGNMFGINFSTTMNDINWVGAVV Mflv_0403|M.gilvum_PYR-GCK SVRTEYGGDKLVRDVATAAKLVDSVNKLGLSMGINFRAVRDMFAWIGPVL Mvan_0271|M.vanbaalenii_PYR-1 RVRVEYGGDRLVRDVETAAKLVQSVNELGLSMGISFAAVRDMFGWIGPVL MAV_1761|M.avium_104 STKNQYSGDALVNQVDIAARLVDHVNSLSNAMGWNFTAAKNMFAWIGPVL MUL_0757|M.ulcerans_Agy99 ------------------HQMVIQMKGMVVDVEELRNHIADFDDFFRPIR .:: :. : . : .: TH_2203|M.thermoresistible__bu TALDTSPVCAADPRCVSAREELRQLTVAGRQGVLDRIAALGRQLEETRGG MMAR_2342|M.marinum_M SALNASPQCNADPACAAARSQLQALVAAQTSGSLSSITALGRTLQQTQEF MAB_0855|M.abscessus_ATCC_1997 RVLVGNPACDMDPGCRSSRDEMNKFLETKQDGTRDKIVELGRELKSVDND MSMEG_4741|M.smegmatis_MC2_155 RALNVSPECNLDPACAASRSDLQRIVEAKDNGNLDKFAELGRQLESTEGD Mb3853c|M.bovis_AF2122/97 GALDSSPMCTADPACASARTELQRLVTARDDGTLAKISELARQLQATRAV Rv3823c|M.tuberculosis_H37Rv GALDSSPMCTADPACASARTELQRLVTARDDGTLAKISELARQLQATRAV MLBr_01231|M.leprae_Br4923 IALDSSVLCDTNPICADARAQFHKLLTASEDGTLDNIAHLWKQLGSTQSS Mflv_0403|M.gilvum_PYR-GCK TALQGNRVCDANPSCVDTRMQFEKLVSAREDGRVDEINQLAGQLQGVDDR Mvan_0271|M.vanbaalenii_PYR-1 AALHGNAVCDANPSCVNTRMQFERLMDARADGRLERINTLAGELEGLDDT MAV_1761|M.avium_104 AALQGNPVCDADSSCSATRATFEQLVGPRGQADLDAIDDLSHQLQAYPDK MUL_0757|M.ulcerans_Agy99 SYFYWEKHCFDIPVCWSLRSVFDTLDGVD---------------LMTEDI : . * . * * : : TH_2203|M.thermoresistible__bu QTIDQTLATLTGTLTDATAALRAAGLDKPGSLQAKIATMQEGADALADAS MMAR_2342|M.marinum_M QTVAQTIAKLETNLNQAVKLLRSIDG-----MQNQLNQMQQGASALAQGS MAB_0855|M.abscessus_ATCC_1997 KQISSTIARLRTALNSIDTNLRRLGLSDSYGIQKRFTEVLTGVNSLADGS MSMEG_4741|M.smegmatis_MC2_155 ETLDEAVSGLQQSIKEATAAARELGLEDASSVKRQLDQLEQGVNLLADSS Mb3853c|M.bovis_AF2122/97 QTLAATVSGLRGALATVIRAMGSLGMSSPGGVRSKINLVNKGVNDLADGS Rv3823c|M.tuberculosis_H37Rv QTLAATVSGLRGALATVIRAMGSLGMSSPGGVRSKINLVNKGVNDLADGS MLBr_01231|M.leprae_Br4923 QTIGATVSGLEKTLTAVNTSLRSLGLDNPNVMRSKMIGLQNGVNDLASAG Mflv_0403|M.gilvum_PYR-GCK QSLTATVNQLNGALAQVTKAISAMGLDTPAGARAGLDDLQDGADRLADGS Mvan_0271|M.vanbaalenii_PYR-1 QSLNSTVKTLNAAMTNIVKAVDELGLDSPGGAQTSLRDIRQGTDRLASGS MAV_1761|M.avium_104 RALKASTDRLRNAFAKLNDVLRAMGMDRPGGLQSNLTTLQNGADQFAGGS MUL_0757|M.ulcerans_Agy99 NNLLPLMERLDTLMPQMTAMMP--------EMIQTMKSMKAQMLSMHSTQ . : * : : : : TH_2203|M.thermoresistible__bu RKLADGVQLLVNQTKEMGSGLGEASSFLLAMKRDATTPAMAGFYIPPEVL MMAR_2342|M.marinum_M RAIAQGVNELVKQTKRMGTGLDEASDFLLQMKHDANKPSMAGFNIPPEAL MAB_0855|M.abscessus_ATCC_1997 AQLAEGVQMLVDQTKQMGGQLGDASTLLVAAKRDAAPGSMSGFYIPQQVL MSMEG_4741|M.smegmatis_MC2_155 HQLAQGVQLLVDQTRNMGQGLDQASQFLLAMKRDASDPQMSGFYIPPQIL Mb3853c|M.bovis_AF2122/97 RQLAEGVQLLVDQVKKMGFGLGEASAFLLAMKDTATTPAMAGFYIPPELL Rv3823c|M.tuberculosis_H37Rv RQLAEGVQLLVDQVKKMGFGLGEASAFLLAMKDTATTPAMAGFYIPPELL MLBr_01231|M.leprae_Br4923 RRIADGVAVLVDQTRTMGTSLARASAFLMEMGQDASQPSMAGFNVPPQLL Mflv_0403|M.gilvum_PYR-GCK RQVAGGVDQLVEQIKVMAAGLDQAAAFLLTMRNDASSSNMAGFSIPAEVL Mvan_0271|M.vanbaalenii_PYR-1 RQVAGGVDQLVEQVRVMADGLNQAAAFLLTMRHDAASANMAGFSIPAEVL MAV_1761|M.avium_104 RQVADAVAQLVDKVKQLGAGLSESAAFLLSLKHDAAHPAMAGFNIPAQLL MUL_0757|M.ulcerans_Agy99 QGLQDQMAAMQEDSSAMGEAFDSS-------------RNDDSFYLPPEVF : : : .. :. : : .* :* : : TH_2203|M.thermoresistible__bu T------------------------QEEFAKAAEIFVSPDGHGVRYLVTT MMAR_2342|M.marinum_M A------------------------KDEFKKAAQIFISPDGHGARYLVQS MAB_0855|M.abscessus_ATCC_1997 T------------------------QDSFKTAAAAFVSADGHAVRYLVQS MSMEG_4741|M.smegmatis_MC2_155 T------------------------QEEFNKAAALFVSPDGRSVRYLVQT Mb3853c|M.bovis_AF2122/97 SYATGESVKAETMPSEYRDLLGGLNVDQLKKVAAAFISPDGHSIRYLIQT Rv3823c|M.tuberculosis_H37Rv SYATGESVKAETMPSEYRDLLGGLNVDQLKKVAAAFISPDGHSIRYLIQT MLBr_01231|M.leprae_Br4923 ------------------------NTEDFKKLVQAFISPDGHSVRYFIQT Mflv_0403|M.gilvum_PYR-GCK G------------------------AVEFQKASEAFVSPDGHSVRYLVQT Mvan_0271|M.vanbaalenii_PYR-1 N------------------------AVEFQKAAEAFISPDGHSVRYLVQT MAV_1761|M.avium_104 R------------------------LPQFQEAAKVFISPDGHSVRYLVQS MUL_0757|M.ulcerans_Agy99 N------------------------NPDFKRGLEQFLSPDGHAVRFIISH .: *:*.**:. *::: TH_2203|M.thermoresistible__bu TLNPFSTEAMDLVNEITETARGARANTELAEADISMAGFTTTLRDTRDYY MMAR_2342|M.marinum_M ALNPFTTAAMDQVDEILDVAHDAQPNSELSDATISMVGIPTGLSDTRDYY MAB_0855|M.abscessus_ATCC_1997 NLNPFSPEAMDQVRAIQEAARSAQPNTTLSDASISMAGLSAMYNDIRNYY MSMEG_4741|M.smegmatis_MC2_155 ALDPFGTAAMDQVKDIVKTAESARPNTSLTDAKISLVGFSSIQNEMRNYY Mb3853c|M.bovis_AF2122/97 DLNPFSTAAMDQIDAITAAARGAQPNTALADAKVSVVGLPVVLKDTRDYS Rv3823c|M.tuberculosis_H37Rv DLNPFSTAAMDQIDAITAAARGAQPNTALADAKVSVVGLPVVLKDTRDYS MLBr_01231|M.leprae_Br4923 DLNPFSSAAMDQVNTILNVATGAQPNTTLSDASIYLSGYTVTLRDTRDYY Mflv_0403|M.gilvum_PYR-GCK KLNPFSSEAMDQVNTISDIARGAQPNTMLSDASISMGGFPAALRDTRDYY Mvan_0271|M.vanbaalenii_PYR-1 RLNPFSPEAMDQVNVINDIARGAQPNTSLADASISMGGFPAALRDTRDYY MAV_1761|M.avium_104 KLSPFSTQAMDQVDAITATARGAQPNTALADAEVSMAGYTVGLKDTRDYY MUL_0757|M.ulcerans_Agy99 EGDPMSQAGINHIDKIKTAAKEAIKGTPLEGSTIYLGGTVAMFKDLSDGN .*: .:: : * * * .: * : : : * : : TH_2203|M.thermoresistible__bu NNDFRLITTLTVVIVFLILVALLRAIVAPLYLIASVVISYLSALGLGVIL MMAR_2342|M.marinum_M NHDIQFIVFATILIVFLILVILLRAIVAPLYLIGSVLVSFLSALGLGVIV MAB_0855|M.abscessus_ATCC_1997 NHDLRFIIVLTVIVVLLILVALLRAIVAPLYLIGSVIISYASAVGIGVIA MSMEG_4741|M.smegmatis_MC2_155 DGDLRFIITVTLIVVFLILAALLRSIIAPIYLVLSVVLSYMSALGIGVVF Mb3853c|M.bovis_AF2122/97 DHDLRLIIAMTVCIVLLILIVLLRAIVAPLYLIGSVIVSYLAALGIGVIV Rv3823c|M.tuberculosis_H37Rv DHDLRLIIAMTVCIVLLILIVLLRAIVAPLYLIGSVIVSYLAALGIGVIV MLBr_01231|M.leprae_Br4923 DRDLQLIVIVTMIVVLLILMALLRSIVAPIYLVGSVIVSYLSALGLCVLV Mflv_0403|M.gilvum_PYR-GCK ERDIRFIIVVTLVIVMLVLMLLLRSLIAPLYLVGSVVVSYFAAIGIGVLV Mvan_0271|M.vanbaalenii_PYR-1 ERDIRFIIIAALIVVLVTLSVLLRSLVAPLYLVGSVVVSYFAAIGIGVLT MAV_1761|M.avium_104 QHDIKFIIAVTLLVVLLTLMALLRAIVAPLYLVATVVISYLSAVGVGVLV MUL_0757|M.ulcerans_Agy99 TFDLMIAGISALCLIFIIMLIITRSVVAAAVIVGTVVLSLGASFGLSVLI *: : :: :::: : : *:::*. :: :*::* ::.*: *: TH_2203|M.thermoresistible__bu FQYILGQELSWSVPGLTFIVLVAVGADYNMLLISRIREESPHGIRSGIIR MMAR_2342|M.marinum_M FQLILGKDLHWSLPGLSFILLVAVGADYNMLLISRIRDESPHGVRVGVIR MAB_0855|M.abscessus_ATCC_1997 FQFIGGQPLSWSVPGMAFIVLVAVGADYNLLFISRIRDESPDGIRSGVIK MSMEG_4741|M.smegmatis_MC2_155 FQFILGKEIVWTVPGMAFLVLVAVGADYNLLLISRIRDEAAHGMRTAVIR Mb3853c|M.bovis_AF2122/97 FQFLLGQEMHWSIPGLTFVILVAVGADYNMLLISRLREEAVLGVRSGVIR Rv3823c|M.tuberculosis_H37Rv FQFLLGQEMHWSIPGLTFVILVAVGADYNMLLISRLREEAVLGVRSGVIR MLBr_01231|M.leprae_Br4923 FQVLLRQQLHWSVPGLAFVVLVAVGADYNMLLASRLRDESSHGLRASVIR Mflv_0403|M.gilvum_PYR-GCK FQLLLGQQLHWSVPPLAFVVLVAVGADYNMLFVSRMRDESPHSVRFGIIR Mvan_0271|M.vanbaalenii_PYR-1 FQLLLGQQLHWSVPPLAFVVLVAVGADYNMLFVSRLRDESPHSVRYGVIR MAV_1761|M.avium_104 FQFLLGQQLHWSVPPLAFVVLVAVGADYNMLLVSRMRDESPHSMRYGIIR MUL_0757|M.ulcerans_Agy99 WQHVLGIELHWLVLAMAVIILLAVGADYNLLLVARLKEEIHAGINTGIIR :* : : * : ::.::*:*******:*: :*:::* .:. .:*: TH_2203|M.thermoresistible__bu TVGHTGGVITSAGLIFAASMFGLVFASITTMIQAGFILGVGLLLDTFLVR MMAR_2342|M.marinum_M TVGSTGGVITSAGLIFAASMFGLLAASITTMVEAGFIIGSGILIDTFLVR MAB_0855|M.abscessus_ATCC_1997 TVKSTGGVITSAGVIFAASMFGLLIGNLQSMVEAGFIIGMGLLLDTFLVR MSMEG_4741|M.smegmatis_MC2_155 TIGATGGVITSAGLIFAASMFGLTFSSLLAAVQIGFIIGVGLLLDTFLVR Mb3853c|M.bovis_AF2122/97 TVASTGGVITAAGLIMAASMYGLVFASLGSVVQGAFVLGTGLLLDTFLVR Rv3823c|M.tuberculosis_H37Rv TVASTGGVITAAGLIMAASMYGLVFASLGSVVQGAFVLGTGLLLDTFLVR MLBr_01231|M.leprae_Br4923 TVRSTGGVITAAGLIFAASMFGLLLSSIATVVQAGFVLGSGILLDTFIVR Mflv_0403|M.gilvum_PYR-GCK TLGSTGGVITAAGLIFAASMAGLLFSSIGIVVQGGFVIGVGILLDTFVVR Mvan_0271|M.vanbaalenii_PYR-1 TLGSTGGVITAAGLIFAASMAGLLFSSIGIVVQGGFVIGVGILLDTFVVR MAV_1761|M.avium_104 TLSSTGGVITAAGLIFAASMSGLLFSSIGTVVQGGVVIGVGILLDTFLVR MUL_0757|M.ulcerans_Agy99 AMGGSGSVVTAAGLVFAFTMMSFAVSELTVMAQVGTTIGMGLLFDTLIVR :: :*.*:*:**:::* :* .: ..: : . :* *:*:**::** TH_2203|M.thermoresistible__bu TITVPATAVLVGRANWWPAKPPHDG------------------------- MMAR_2342|M.marinum_M SVTVPAMAAMLGQANWWPSKIGASSTRRRVYQRAGSRKPNLLDRIKSLGP MAB_0855|M.abscessus_ATCC_1997 TITIPALVVLCGQANWWPSASVESWFR----QRFSRSKPDAQE-----GD MSMEG_4741|M.smegmatis_MC2_155 TITVPAAAVLIGKLSWWP------------------TKPPAP-------- Mb3853c|M.bovis_AF2122/97 TVTVPAIAVLVGQANWWLPSSWRPATWWPLGRRRGRAQRTKRKPLLPKEE Rv3823c|M.tuberculosis_H37Rv TVTVPAIAVLVGQANWWLPSSWRPATWWPLGRRRGRAQRTKRKPLLPKEE MLBr_01231|M.leprae_Br4923 TITVPAVAALLRRASWWPARPWGNNA------------------------ Mflv_0403|M.gilvum_PYR-GCK TITVPAIATLLGRANWWPSRVA---APARERVSADT-------------- Mvan_0271|M.vanbaalenii_PYR-1 TITVPAIAALVGRANWWPSKVGPQQAAPRAVESAGSG------------- MAV_1761|M.avium_104 TVTVPAIAALAGRANWWPSRIA----VRRNPVSGQP-------------- MUL_0757|M.ulcerans_Agy99 SFMTPSIAALLGKWFWWPQVVRQRPAPQPWPTPAPTPPPATTSV------ :. *: ..: : ** TH_2203|M.thermoresistible__bu -------------------------------------------------- MMAR_2342|M.marinum_M AKQRAAVTAKASTTTTKRPSTAVKKRGELVSKPGTRKRVRKPAWPDIPIT MAB_0855|M.abscessus_ATCC_1997 CAVSDDPEAASGESSPEEPLISASREVELAGRR----------------- MSMEG_4741|M.smegmatis_MC2_155 ------------EPAPTEPTVAPAAQA----------------------- Mb3853c|M.bovis_AF2122/97 EEQSPPDDDDLIGLWLHDGLRL---------------------------- Rv3823c|M.tuberculosis_H37Rv EEQSPPDDDDLIGLWLHDGLRL---------------------------- MLBr_01231|M.leprae_Br4923 -------------------------------------------------- Mflv_0403|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_0271|M.vanbaalenii_PYR-1 -------------------------------------------------- MAV_1761|M.avium_104 -------------------------------------------------- MUL_0757|M.ulcerans_Agy99 -------------------------------------------------- TH_2203|M.thermoresistible__bu -------------------------------------------------- MMAR_2342|M.marinum_M NDDYESLQEHALPLFGSIRLPRELTPIDPALHNGDGATSNGDGTTNGSGA MAB_0855|M.abscessus_ATCC_1997 -------------------------------------------------- MSMEG_4741|M.smegmatis_MC2_155 -------------------------------------------------- Mb3853c|M.bovis_AF2122/97 -------------------------------------------------- Rv3823c|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_01231|M.leprae_Br4923 -------------------------------------------------- Mflv_0403|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_0271|M.vanbaalenii_PYR-1 -------------------------------------------------- MAV_1761|M.avium_104 -------------------------------------------------- MUL_0757|M.ulcerans_Agy99 -------------------------------------------------- TH_2203|M.thermoresistible__bu -------------------------------------------------- MMAR_2342|M.marinum_M DCKQLQLIGLGDTTEFRVPNGTTNGNGNGNGHTNGNGHTNGNGHTNGNGH MAB_0855|M.abscessus_ATCC_1997 -------------------------------------------------- MSMEG_4741|M.smegmatis_MC2_155 -------------------------------------------------- Mb3853c|M.bovis_AF2122/97 -------------------------------------------------- Rv3823c|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_01231|M.leprae_Br4923 -------------------------------------------------- Mflv_0403|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_0271|M.vanbaalenii_PYR-1 -------------------------------------------------- MAV_1761|M.avium_104 -------------------------------------------------- MUL_0757|M.ulcerans_Agy99 -------------------------------------------------- TH_2203|M.thermoresistible__bu -------------------------------------------------- MMAR_2342|M.marinum_M TNGTNGHGTNGATNGNGHTNGTNGTNGHGTNGATNGHTNGTNGNGHTNGT MAB_0855|M.abscessus_ATCC_1997 -------------------------------------------------- MSMEG_4741|M.smegmatis_MC2_155 -------------------------------------------------- Mb3853c|M.bovis_AF2122/97 -------------------------------------------------- Rv3823c|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_01231|M.leprae_Br4923 -------------------------------------------------- Mflv_0403|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_0271|M.vanbaalenii_PYR-1 -------------------------------------------------- MAV_1761|M.avium_104 -------------------------------------------------- MUL_0757|M.ulcerans_Agy99 -------------------------------------------------- TH_2203|M.thermoresistible__bu -------------------------------------------------- MMAR_2342|M.marinum_M NGHGTNGATNGNGHTNGTNGTNGHGTNGATNGHTNGNGNGTNGNGNGTNG MAB_0855|M.abscessus_ATCC_1997 -------------------------------------------------- MSMEG_4741|M.smegmatis_MC2_155 -------------------------------------------------- Mb3853c|M.bovis_AF2122/97 -------------------------------------------------- Rv3823c|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_01231|M.leprae_Br4923 -------------------------------------------------- Mflv_0403|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_0271|M.vanbaalenii_PYR-1 -------------------------------------------------- MAV_1761|M.avium_104 -------------------------------------------------- MUL_0757|M.ulcerans_Agy99 -------------------------------------------------- TH_2203|M.thermoresistible__bu -------------------------------------------------- MMAR_2342|M.marinum_M HGTNGHTNGNGTNGATNGASNGATNGTNGHTNGNGNGNGTNGHTSGNGNG MAB_0855|M.abscessus_ATCC_1997 -------------------------------------------------- MSMEG_4741|M.smegmatis_MC2_155 -------------------------------------------------- Mb3853c|M.bovis_AF2122/97 -------------------------------------------------- Rv3823c|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_01231|M.leprae_Br4923 -------------------------------------------------- Mflv_0403|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_0271|M.vanbaalenii_PYR-1 -------------------------------------------------- MAV_1761|M.avium_104 -------------------------------------------------- MUL_0757|M.ulcerans_Agy99 -------------------------------------------------- TH_2203|M.thermoresistible__bu -------------------------------------------------- MMAR_2342|M.marinum_M TNGATNGASNGATNGTNGHTNGNGNGTNGATNGHTNGNGNGTNGHTSGNG MAB_0855|M.abscessus_ATCC_1997 -------------------------------------------------- MSMEG_4741|M.smegmatis_MC2_155 -------------------------------------------------- Mb3853c|M.bovis_AF2122/97 -------------------------------------------------- Rv3823c|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_01231|M.leprae_Br4923 -------------------------------------------------- Mflv_0403|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_0271|M.vanbaalenii_PYR-1 -------------------------------------------------- MAV_1761|M.avium_104 -------------------------------------------------- MUL_0757|M.ulcerans_Agy99 -------------------------------------------------- TH_2203|M.thermoresistible__bu -------------------------------------------------- MMAR_2342|M.marinum_M NGTNGATNGASNGATNGTNGHTNGNGNGNGTNGATNEHGTNGSTNGDIDD MAB_0855|M.abscessus_ATCC_1997 -------------------------------------------------- MSMEG_4741|M.smegmatis_MC2_155 -------------------------------------------------- Mb3853c|M.bovis_AF2122/97 -------------------------------------------------- Rv3823c|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_01231|M.leprae_Br4923 -------------------------------------------------- Mflv_0403|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_0271|M.vanbaalenii_PYR-1 -------------------------------------------------- MAV_1761|M.avium_104 -------------------------------------------------- MUL_0757|M.ulcerans_Agy99 -------------------------------------------------- TH_2203|M.thermoresistible__bu ---------------------- MMAR_2342|M.marinum_M ADEGHALPLFGPSNQRDLLIKR MAB_0855|M.abscessus_ATCC_1997 ---------------------- MSMEG_4741|M.smegmatis_MC2_155 ---------------------- Mb3853c|M.bovis_AF2122/97 ---------------------- Rv3823c|M.tuberculosis_H37Rv ---------------------- MLBr_01231|M.leprae_Br4923 ---------------------- Mflv_0403|M.gilvum_PYR-GCK ---------------------- Mvan_0271|M.vanbaalenii_PYR-1 ---------------------- MAV_1761|M.avium_104 ---------------------- MUL_0757|M.ulcerans_Agy99 ----------------------