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M. thermoresistible (build 8) TH_3222 (-)

annotation: virulence factor Mce family protein
coordinates: 3116941 - 3117969
length: 343

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_3222--100% (343)virulence factor Mce family protein
M. thermoresistible (build 8)TH_3704-e-12163.13% (339) PUTATIVE virulence factor Mce family protein
M. thermoresistible (build 8)TH_3213-e-12161.99% (342) PUTATIVE virulence factor Mce family protein

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb0605mce2B2e-8149.27% (341) MCE-family protein MCE2B
M. gilvum PYR-GCKMflv_0651-1e-13770.41% (338) virulence factor Mce family protein
M. tuberculosis H37RvRv1967mce3B1e-12464.62% (342) MCE-family protein MCE3B
M. leprae Br4923MLBr_02590mce1B7e-7445.06% (344) putative secreted protein
M. abscessus ATCC 19977MAB_4152c-3e-6139.22% (334) MCE-family protein
M. marinum MMMAR_4052mce3B_11e-12966.47% (343) MCE-family protein Mce3B_1
M. avium 104MAV_2533-1e-12765.79% (342) virulence factor Mce family protein
M. smegmatis MC2 155MSMEG_0347-1e-11258.48% (342) virulence factor Mce family protein
M. ulcerans Agy99MUL_3919mce3B_11e-12866.18% (343) MCE-family protein Mce3B_1
M. vanbaalenii PYR-1Mvan_4603-1e-13570.36% (334) virulence factor Mce family protein

CLUSTAL 2.0.9 multiple sequence alignment


Mb0605|M.bovis_AF2122/97            -----MKTTGTTIKLGIVWLVLSVFTVMIIVVFGQVRFHHTT-GYSAVFT
MLBr_02590|M.leprae_Br4923          -----MKLTGTVVRLSIFSLVLLLFTVMIIVVFGQMRFGRTN-GYTAEFT
TH_3222|M.thermoresistible__bu      ---LRKNLSGLVLRLTVFVVVCALGAFGLIAIFAQLRFQEED-TYHAIFT
Mflv_0651|M.gilvum_PYR-GCK          ---MTNKISAVLWRLGIFVVVCALGAFALIAVFAQLRFEREQ-RYTAVFA
MAV_2533|M.avium_104                ---MKENLTGTLWRLAIYVVVSVLGMFTLVAVFGQLRFQSEK-TYKAQFA
Rv1967|M.tuberculosis_H37Rv         ---MRENLGGVVVRLGVFLAVCLLTAFLLIAVFGEVRFGDGK-TYYAEFA
MMAR_4052|M.marinum_M               ---MRARLIRDAIRLGTFLLVCFLGVIGLFAVFGQLRFGEKTSTYKAEFS
MUL_3919|M.ulcerans_Agy99           ---MRARLIRDAIRLGTFLLVCFLGVIGLFAVFGQLRFGEKTSTYKAEFS
Mvan_4603|M.vanbaalenii_PYR-1       MPGLTTRVRHDALRLGVFLTVCLVGVFGLFAVFGQMRFGEKTHSYKAAFS
MSMEG_0347|M.smegmatis_MC2_155      ---MNKEVLSTLIRVSAFLTVCAVGVFALFSIFADLRFGERK-QYTAQFS
MAB_4152c|M.abscessus_ATCC_199      ------MKRATQIKVIVFTVVMLLVAAGLIITFGEFRFGSGK-RYHAMFS
                                                 ::     *  :    :.  *.:.**      * * *:

Mb0605|M.bovis_AF2122/97            HVSGLRAGQFVRAAGVEVGKVAKVTLIDGDKQVLVDFTVDRSLSLDQATT
MLBr_02590|M.leprae_Br4923          NISGLRTGQFVRASGVEVGKVNSVALINGGTRVRVKFNVDRSVPLYQSTT
TH_3222|M.thermoresistible__bu      SVTGLENGNFVRIAGVEVGKVKHVSVRD-DSTVLVKFSADRSVVLTEGSR
Mflv_0651|M.gilvum_PYR-GCK          NVSGLTSGDFVRIAGVEVGKVRTLTVRD-DSTVAVEFGADDSVVLTDGSR
MAV_2533|M.avium_104                NVSGLEGGNFVRIAGVEVGKVKNITVEP-DSTVLVEFTAAEKVVLTEGTR
Rv1967|M.tuberculosis_H37Rv         NVSNLRTGKLVRIAGVEVGKVTRISINP-DATVRVQFTADNSVTLTRGTR
MMAR_4052|M.marinum_M               NVTGLEQNDFVRIAGVEVGQVKKVAIQP-DTTALVEFTADSSVVLTQGSR
MUL_3919|M.ulcerans_Agy99           NVTGLEQNDFVRIAGVEVGQVKKVAIQP-DTTALVEFTADSSVVLTQGSR
Mvan_4603|M.vanbaalenii_PYR-1       NVTGLENGDFVRIAGVEVGQVKKVAIQP-DTTALVEFTADQSVVLTEGSR
MSMEG_0347|M.smegmatis_MC2_155      DISGLKEGDFVRIAGVEVGQVQKVSMDE-NALVLVEFAMEDSVELTSTST
MAB_4152c|M.abscessus_ATCC_199      TASDLRSGQKVRIAGVPVGRVKNVSLNR-DNSVEVTFDVDSKYQLYSSSR
                                      :.*  .. ** :** **:*  :::   .  . * *    .  *   : 

Mb0605|M.bovis_AF2122/97            ASIRYLNLIGDRYLELGRG---HSGQRLAPGATIPLEHTHPALDLDALLG
MLBr_02590|M.leprae_Br4923          AQIRYLDLIGNRYLELKHGEGQGSEKIMPAGGLIPLSRTSPALDLDALIG
TH_3222|M.thermoresistible__bu      AIIRYDNLIGGRYLALEEGA--GGTTKLAPGETIPLDRTAPALDLDALIG
Mflv_0651|M.gilvum_PYR-GCK          AVIKYDNLIGDRYLAIEEGA--GGTTKLRPGDAIPLDRTAPALDLDAVIG
MAV_2533|M.avium_104                AAIRFADLTGGRYVALEEGA--GNIRRLSPGATIPLARTEPALDLDALIG
Rv1967|M.tuberculosis_H37Rv         AVIRYDNLFGDRYLALEEGA--GGLAVLRPGHTIPLARTQPALDLDALIG
MMAR_4052|M.marinum_M               AVIRYDDLIGGRYLALEEGA--GSPKQLKPGDTIPMTHTSPALDLDALIG
MUL_3919|M.ulcerans_Agy99           AVIRYDDLIGGRYLALEEGA--GSPKQLKPGDTIPMTHTSPALDLDALIG
Mvan_4603|M.vanbaalenii_PYR-1       AVIRYDDLIGGRYLALQEGA--GATTTLKPGETIPLARTAPALDLDALIG
MSMEG_0347|M.smegmatis_MC2_155      AVIRYDNLIGGRYLELKQGE--EPGAVLQAGATIPLARTRPALDLDELIG
MAB_4152c|M.abscessus_ATCC_199      AIIRYENLVGDRYLEITAGP--GELHKLPDGGTLDKEHTQPALDLDALLG
                                    * *:: :* *.**: :  *        :  *  :   :* ****** ::*

Mb0605|M.bovis_AF2122/97            GFRPLFQTLDPDKVNSIASSIITVFQGQGATINDILDQTASLTATLADRD
MLBr_02590|M.leprae_Br4923          GFKPLFRALDPDKINTIASAIVAAFQGQGGTINDILDQTAQLTTAIGERD
TH_3222|M.thermoresistible__bu      GFRPLFHALDPAHVNALSGQLIAAFQGQGPTIGSILEQTATLTNTLADRD
Mflv_0651|M.gilvum_PYR-GCK          GFRPLLNALDPTQVNTLTSQLIAAFQGQGATIGSILAQTAALTNTLADRD
MAV_2533|M.avium_104                GFRPLFRALDPDQVNKLTGQLIAAFQGQGGTIGSFLTQAAALTNTLADRD
Rv1967|M.tuberculosis_H37Rv         GFKPLFRALNPEQVNALSEQLLHAFAGQGPTIGSLLAQSAAVTNTLADRD
MMAR_4052|M.marinum_M               GFRPLLKALDPEQVNALSGQLIRALQGEGATINSFLAQTAALTTTLADRD
MUL_3919|M.ulcerans_Agy99           GFRPLLKALDPDQVNALSGQLIRALQGEGATINSFLAQTAALTTTLADRD
Mvan_4603|M.vanbaalenii_PYR-1       GFRPLFRALDPEQVNALSGQLISALQGQGGTINSFLAQTATLTSTLADRD
MSMEG_0347|M.smegmatis_MC2_155      GFRPLFKALDPDQVNALSTQLVQVFQGQGATISSFLDQTAAMTSTLADRD
MAB_4152c|M.abscessus_ATCC_199      GLRPVLKGFDAAKVNEISNAFIQILQGQGGTLSQLLGDTSSFTSGLAERD
                                    *::*::. ::. ::* ::  ::  : *:* *:..:* ::: .*  :.:**

Mb0605|M.bovis_AF2122/97            HAIGEVVNNLNTVLATTVKHQTEFDRTVDKLEVLITGLKNRADPLAAAAA
MLBr_02590|M.leprae_Br4923          QAIGEVVKNLNVVLDTTVRHRKEFDQTVNNLEILITGLKDHGDQLAGSFA
TH_3222|M.thermoresistible__bu      ELIGQVVVNLNTVLASLGGHSDQFAEAVDSLSDLIHGLQGRKETISAGLA
Mflv_0651|M.gilvum_PYR-GCK          ELIGQTIVNLNVVLGSLAGHSDQFGKAIDSLSQLVHGLQARKQDISNGVA
MAV_2533|M.avium_104                HLIGQVIVNLNTVLGSLGGQSGQFARAVDSLSELVAGLEARKQDISNGMA
Rv1967|M.tuberculosis_H37Rv         RLIGQVITNLNVVLGSLGAHTDRLDQAVTSLSALIHRLAQRKTDISNAVA
MMAR_4052|M.marinum_M               QLIGDVIINLNVVLGSLGDQNKQFAKAVDALAELMEGLQARKEDITKGVA
MUL_3919|M.ulcerans_Agy99           QLIGDVIINLNVVLGSLGDQNKQFAKAVDALAELMEGLQARKEDITKGMA
Mvan_4603|M.vanbaalenii_PYR-1       QLIGEVITNLNVVLGSLGDQNDQFAKAIDSLADLVQTLRDRKEDVSNGLA
MSMEG_0347|M.smegmatis_MC2_155      QLIGEVIGNLDVLLGSLGEQSHQFDKAVNSLSELVAGLSARRTDITNAIA
MAB_4152c|M.abscessus_ATCC_199      QLIGDVINHLNEVLATVDSKSTQFSSSVDQLQQLISGLAQQRDVVAGALP
                                    . **:.: :*: :* :   :  .:  ::  *  *:  *  :   :: . .

Mb0605|M.bovis_AF2122/97            HISSAAGTLADLLGADRPLLHSSFGHLEGIQQPLIDELAELDHVLGKLPD
MLBr_02590|M.leprae_Br4923          HISNAAGTVANLLAEDHALLHKSINYLDGIQQPLIDQRLQLEDYLHKLPT
TH_3222|M.thermoresistible__bu      KAGEGARTLAELLSQAREPLTKTVRETDRAAGVVLGDHEYFDDLLNTLPD
Mflv_0651|M.gilvum_PYR-GCK          YANEAARSIADLLAQARPPLQKAVHETDRTATAVLADRDYFDNLLNTLPD
MAV_2533|M.avium_104                YANAAAGSITDLLAQARPPVKKVVHEADRTAGTMLADREWLEKYLDHWPD
Rv1967|M.tuberculosis_H37Rv         YTNAAAGSVADLLSQARAPLAKVVRETDRVAGIAAADHDYLDNLLNTLPD
MMAR_4052|M.marinum_M               YTNAAASSIADLLSQARPPLTKTVQETDRASAIVLADHEYFDNLINTLPD
MUL_3919|M.ulcerans_Agy99           YTNAAASSIADLLSQARPPLAKTVQETDRASAIVLADHEYFDNLINTLPD
Mvan_4603|M.vanbaalenii_PYR-1       YTNAAAASIADLLAQARPPLAKTIKETDRSAAIVVADHEYFDNFLNTLPD
MSMEG_0347|M.smegmatis_MC2_155      NSDNAATEIADLLAQARPPLQNVVTQADRAAAIAVADHEYLDNILNTLPD
MAB_4152c|M.abscessus_ATCC_199      PLASTASSLESVLKDTRPYIKGTIEQARQLATRVDERKADVNVVVENLAE
                                         *  : .:*   :  :   .                .:  :   . 

Mb0605|M.bovis_AF2122/97            AYRIIGRAGGIYGDFFNFYLCDISLKVNGLQPGGPVRTVKLFGQP---TG
MLBr_02590|M.leprae_Br4923          VLNQIGRTIGSYGDFVNFYSCDITLKINGLQPGGPVRTVRLFQQP---TG
TH_3222|M.thermoresistible__bu      AYRVLGRQ-AMSGDFFNFYLCDLVLKMNGK--GGQPVYVKVAGQD---TG
Mflv_0651|M.gilvum_PYR-GCK          TYRVMLRQ-GLYGNYFTFYLCDLLLKVNGK--GGQPVYIKLVEQS---SG
MAV_2533|M.avium_104                AFKILNRQ-GLYGDFFSFYLCDIVLKLNGK--GGQPVYVKVAGQA---SG
Rv1967|M.tuberculosis_H37Rv         KYQALVRQ-GMYGDFFAFYLCDVVLKVNGK--GGQPVYIKLAGQD---SG
MMAR_4052|M.marinum_M               AYQALSRQ-GIYGDFFSFYLCDVVLKLNGR--GGQPVYVKVAGQP---TG
MUL_3919|M.ulcerans_Agy99           AYQALSRQ-GIYGDFFSFYLCDVVLKLNGR--GGQPVYVKVAGQP---TG
Mvan_4603|M.vanbaalenii_PYR-1       AYQALARQ-GIYGDFFSFYLCDIVLKLNGK--GGQPVYVKVAGQS---TG
MSMEG_0347|M.smegmatis_MC2_155      KYRVLGRQ-AMYGDYFSFYLCDLILKLNGK--GGQPVYVKLAEQV---TG
MAB_4152c|M.abscessus_ATCC_199      NYLRLNAL-GAYGSFFNIYYCSIRIKVNGP--VGTDWLIPFGGPPDPSKG
                                        :    .  *.:. :* *.: :*:**    *    : .       .*

Mb0605|M.bovis_AF2122/97            RCTPQ--
MLBr_02590|M.leprae_Br4923          RCTPQ--
TH_3222|M.thermoresistible__bu      RCAPR--
Mflv_0651|M.gilvum_PYR-GCK          RCTPQ--
MAV_2533|M.avium_104                RCTPR--
Rv1967|M.tuberculosis_H37Rv         RCAPK--
MMAR_4052|M.marinum_M               RCAPR--
MUL_3919|M.ulcerans_Agy99           RCAPR--
Mvan_4603|M.vanbaalenii_PYR-1       RCAPR--
MSMEG_0347|M.smegmatis_MC2_155      RCAPK--
MAB_4152c|M.abscessus_ATCC_199      RCAFKNE
                                    **: :