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M. thermoresistible (build 8) TH_3704 (-)

annotation: virulence factor Mce family protein
coordinates: 397395 - 398525
length: 377

aa seq not available

Operon Prediction Model: Genebank

Paralogs

species id gene e-value identity (len) annotation
M. thermoresistible (build 8) TH_3704 - - 100% (377) virulence factor Mce family protein
M. thermoresistible (build 8) TH_3222 - e-121 63.13% (339) PUTATIVE virulence factor Mce family protein
M. thermoresistible (build 8) TH_3213 - e-111 59.10% (335) PUTATIVE virulence factor Mce family protein

Closest Orthologs (e-value cutoff: 1e-4)

species id gene e-value identity (len) annotation
M. bovis AF2122 / 97 Mb0176 mce1B 7e-76 45.64% (344) MCE-family protein MCE1B
M. gilvum PYR-GCK Mflv_2102 - 1e-118 62.94% (340) virulence factor Mce family protein
M. tuberculosis H37Rv Rv1967 mce3B 1e-121 64.31% (339) MCE-family protein MCE3B
M. leprae Br4923 MLBr_02590 mce1B 1e-73 43.90% (344) putative secreted protein
M. abscessus ATCC 19977 MAB_4152c - 1e-60 36.76% (340) MCE-family protein
M. marinum M MMAR_2883 mce3B 1e-126 65.09% (338) MCE-family protein Mce3B
M. avium 104 MAV_2533 - 1e-120 63.72% (339) virulence factor Mce family protein
M. smegmatis MC2 155 MSMEG_0347 - 1e-113 61.45% (332) virulence factor Mce family protein
M. ulcerans Agy99 MUL_2869 mce3B 1e-124 64.20% (338) MCE-family protein Mce3B
M. vanbaalenii PYR-1 Mvan_3981 - 1e-131 69.73% (337) virulence factor Mce family protein

CLUSTAL 2.0.9 multiple sequence alignment


Mb0176|M.bovis_AF2122/97            ------------------------------------MKITGTVVKLGIVS
MLBr_02590|M.leprae_Br4923          ------------------------------------MKLTGTVVRLSIFS
MMAR_2883|M.marinum_M               ----------------------------------MREDLRGVVIRLGVFL
MUL_2869|M.ulcerans_Agy99           ----------------------------------MREDLRGVVIRLGVFL
Rv1967|M.tuberculosis_H37Rv         ----------------------------------MRENLGGVVVRLGVFL
Mvan_3981|M.vanbaalenii_PYR-1       ----------------------------------MKDDFKGAAWRLLVFL
TH_3704|M.thermoresistible__bu      VARCAAGGAGTRSGAAGQQRPDTTVKRDDIHRGEFVGSLRAAVWRLAVFL
Mflv_2102|M.gilvum_PYR-GCK          ----------------------------------MSVSIRRDATRLGAFL
MAV_2533|M.avium_104                ----------------------------------MKENLTGTLWRLAIYV
MSMEG_0347|M.smegmatis_MC2_155      ----------------------------------MNKEVLSTLIRVSAFL
MAB_4152c|M.abscessus_ATCC_199      -------------------------------------MKRATQIKVIVFT
                                                                                ::    

Mb0176|M.bovis_AF2122/97            VVLLFFTVMIIVIFGQMRFDRT-NGYTAEFSNVSGLRQGQFVRASGVEIG
MLBr_02590|M.leprae_Br4923          LVLLLFTVMIIVVFGQMRFGRT-NGYTAEFTNISGLRTGQFVRASGVEVG
MMAR_2883|M.marinum_M               TVCALTAFLLVAVFGQVRFGDG-NTYYAEFSNVSNLREGKLVRIAGVEVG
MUL_2869|M.ulcerans_Agy99           TVCALTAFLLVAVFGQVRFGDG-NTYYAEFSNVSNLREGKLVRIAGVEVG
Rv1967|M.tuberculosis_H37Rv         AVCLLTAFLLIAVFGEVRFGDG-KTYYAEFANVSNLRTGKLVRIAGVEVG
Mvan_3981|M.vanbaalenii_PYR-1       SVCALATFALLTVFAQFRFGDG-RTYFAEFDNVSGLKSDDLVRIAGVEVG
TH_3704|M.thermoresistible__bu      VVCLFGAFTLLAVFAELRFDRG-VNYFAEFANVSGLKEGDMVRIAGVEVG
Mflv_2102|M.gilvum_PYR-GCK          AVCLLGVFGLFAVFGQMRFGEKTQQYRAEFVNVTGLETNDFVRIAGVEVG
MAV_2533|M.avium_104                VVSVLGMFTLVAVFGQLRFQSE-KTYKAQFANVSGLEGGNFVRIAGVEVG
MSMEG_0347|M.smegmatis_MC2_155      TVCAVGVFALFSIFADLRFGER-KQYTAQFSDISGLKEGDFVRIAGVEVG
MAB_4152c|M.abscessus_ATCC_199      VVMLLVAAGLIITFGEFRFGSG-KRYHAMFSTASDLRSGQKVRIAGVPVG
                                     *  .    :.  *.:.**      * * *   :.*. .. ** :** :*

Mb0176|M.bovis_AF2122/97            KVKALHLVDGGRRVRVEFNIDRSVPLYQSTTAQIRYSDLIGNRYVELKRG
MLBr_02590|M.leprae_Br4923          KVNSVALINGGTRVRVKFNVDRSVPLYQSTTAQIRYLDLIGNRYLELKHG
MMAR_2883|M.marinum_M               KVEKISINPDS-TVKVGFTADNSVTLTQGTQAVIRYDNLFGDRYLALE--
MUL_2869|M.ulcerans_Agy99           KVEKISINPDA-TVKVEFTADNSVTLTQGTQAVIRYDNLFGDRYLALE--
Rv1967|M.tuberculosis_H37Rv         KVTRISINPDA-TVRVQFTADNSVTLTRGTRAVIRYDNLFGDRYLALE--
Mvan_3981|M.vanbaalenii_PYR-1       NIEDISFKADS-TVRVEFSADESVVVTDGTRAAIRYDNVIGGRYLALE--
TH_3704|M.thermoresistible__bu      KVQNIAVNRDG-TVRVGFSAEESVVLTEGSRAQIRYDDPIGNRFLALL--
Mflv_2102|M.gilvum_PYR-GCK          KVENVEIQPDT-TAVVEFTADDSVVLTQGSRAVIRYDDLIGGRYLALE--
MAV_2533|M.avium_104                KVKNITVEPDS-TVLVEFTAAEKVVLTEGTRAAIRFADLTGGRYVALE--
MSMEG_0347|M.smegmatis_MC2_155      QVQKVSMDENA-LVLVEFAMEDSVELTSTSTAVIRYDNLIGGRYLELK--
MAB_4152c|M.abscessus_ATCC_199      RVKNVSLNRDN-SVEVTFDVDSKYQLYSSSRAIIRYENLVGDRYLEIT--
                                    .:  : .  .   . * *    .  :   : * **: :  *.*:: :   

Mb0176|M.bovis_AF2122/97            EGKGANDLLPPGGLIPLSRTSPALDLDALIGGFKPVFRALDPAKVNNIAN
MLBr_02590|M.leprae_Br4923          EGQGSEKIMPAGGLIPLSRTSPALDLDALIGGFKPLFRALDPDKINTIAS
MMAR_2883|M.marinum_M               EGAGGLTILKPGQTIPLANTKPALDLDALIGGFRPLFRALDPHQVNALSD
MUL_2869|M.ulcerans_Agy99           EGAGGLTILKPGQTIPLANTKPALDFDDLIDGFRPLFRALDPHQVNALSD
Rv1967|M.tuberculosis_H37Rv         EGAGGLAVLRPGHTIPLARTQPALDLDALIGGFKPLFRALNPEQVNALSE
Mvan_3981|M.vanbaalenii_PYR-1       EGAGGLRALPAGGTIPVTRTQPALDLDSVIGGFRPLFRALDADQVNALSG
TH_3704|M.thermoresistible__bu      EGAGGVARLAPGDTIPVDRTDPALDLDAVIGGFRPLFRALDADQVNALTG
Mflv_2102|M.gilvum_PYR-GCK          EGAGGTQKLNPGGTIPLARTSPALDLDALIGGFRPLFRALDPDQINALSG
MAV_2533|M.avium_104                EGAGNIRRLSPGATIPLARTEPALDLDALIGGFRPLFRALDPDQVNKLTG
MSMEG_0347|M.smegmatis_MC2_155      QGEEPGAVLQAGATIPLARTRPALDLDELIGGFRPLFKALDPDQVNALST
MAB_4152c|M.abscessus_ATCC_199      AGPGELHKLPDGGTLDKEHTQPALDLDALLGGLRPVLKGFDAAKVNEISN
                                     *      :  *  :   .* ****:* ::.*::*:::.::. ::* :: 

Mb0176|M.bovis_AF2122/97            ALITVFQGQGGTINDTLDQTAQLTSQIAERDQAIGEVVKNLNIVLDTTVK
MLBr_02590|M.leprae_Br4923          AIVAAFQGQGGTINDILDQTAQLTTAIGERDQAIGEVVKNLNVVLDTTVR
MMAR_2883|M.marinum_M               QLLQAFQGQGPTIGTFLDQAAAVTNTLADRDQLIGQVVTNLNVVLGSLGG
MUL_2869|M.ulcerans_Agy99           QLLQAFQGQGPTIGTFLDQAAAVTNTLADRDQLIGQVVTNLNVVLGSLGG
Rv1967|M.tuberculosis_H37Rv         QLLHAFAGQGPTIGSLLAQSAAVTNTLADRDRLIGQVITNLNVVLGSLGA
Mvan_3981|M.vanbaalenii_PYR-1       QLISALQGQGATIGSFLEQAAAVTNTLADRDMLIGQVVDNLNVVLGSLGG
TH_3704|M.thermoresistible__bu      QLIKAFSGQGPTIASFLDQAAAVTNTLADRDVLIGEVIDNLATVLGTLGG
Mflv_2102|M.gilvum_PYR-GCK          QLISALQGQGGTINSFLAQTAALTSTLADRDQLIGEVIINLNTVLGSLGD
MAV_2533|M.avium_104                QLIAAFQGQGGTIGSFLTQAAALTNTLADRDHLIGQVIVNLNTVLGSLGG
MSMEG_0347|M.smegmatis_MC2_155      QLVQVFQGQGATISSFLDQTAAMTSTLADRDQLIGEVIGNLDVLLGSLGE
MAB_4152c|M.abscessus_ATCC_199      AFIQILQGQGGTLSQLLGDTSSFTSGLAERDQLIGDVINHLNEVLATVDS
                                     ::  : *** *:   * ::: .*. :.:**  **:*: :*  :* :   

Mb0176|M.bovis_AF2122/97            HRKEFDETVNNLENLITGLRNHSDQLAGGLAHISNGAGTVADLLAENRTL
MLBr_02590|M.leprae_Br4923          HRKEFDQTVNNLEILITGLKDHGDQLAGSFAHISNAAGTVANLLAEDHAL
MMAR_2883|M.marinum_M               QSDRLDKAVASLSQLIAGLSERRTDISNAVAYTNAAAGSVADLLSQARAP
MUL_2869|M.ulcerans_Agy99           QSDRLDKAVASLSQLIAGLSERRTDISNAVAYTNAAAGSVADLLSKARAP
Rv1967|M.tuberculosis_H37Rv         HTDRLDQAVTSLSALIHRLAQRKTDISNAVAYTNAAAGSVADLLSQARAP
Mvan_3981|M.vanbaalenii_PYR-1       QTDRLDLAVTSLSELVHGLAERRVDISNSLAYIDAAAGSVADLLAQSREP
TH_3704|M.thermoresistible__bu      HSERFDQAVDSLSELVSGLSVRRSELSQAIAGIDSGAGSFADLLADAREP
Mflv_2102|M.gilvum_PYR-GCK          QSDQFAKAVDSLSQLVEGLSDRRQEISDGLAYTNAAAGSIADFLTEARPP
MAV_2533|M.avium_104                QSGQFARAVDSLSELVAGLEARKQDISNGMAYANAAAGSITDLLAQARPP
MSMEG_0347|M.smegmatis_MC2_155      QSHQFDKAVNSLSELVAGLSARRTDITNAIANSDNAATEIADLLAQARPP
MAB_4152c|M.abscessus_ATCC_199      KSTQFSSSVDQLQQLISGLAQQRDVVAGALPPLASTASSLESVLKDTRPY
                                    :  .:  :* .*. *:  *  :   :: ...     *  . ..* . :  

Mb0176|M.bovis_AF2122/97            VRKAVSYLDAIQQPVIDQRVELDDLLHKTPTALTALGRANGTYGDFQNFY
MLBr_02590|M.leprae_Br4923          LHKSINYLDGIQQPLIDQRLQLEDYLHKLPTVLNQIGRTIGSYGDFVNFY
MMAR_2883|M.marinum_M               LSKALHETDRVATIALADHDYLDNLLNTLPDRYQALVRQ-GMYGDFFAFY
MUL_2869|M.ulcerans_Agy99           FSKALHETDRVATIALADHDYLDNLLNTLPDRYQALVRQ-GMYGDFFAFY
Rv1967|M.tuberculosis_H37Rv         LAKVVRETDRVAGIAAADHDYLDNLLNTLPDKYQALVRQ-GMYGDFFAFY
Mvan_3981|M.vanbaalenii_PYR-1       FSTVVHETDRSAGIAVADHVYLDNLLNTLPDKYRALGRQ-GMYGDFFSFY
TH_3704|M.thermoresistible__bu      FRRVVHELDRVAAIAVADHEYLDELLNRLPDKYRALNRQ-ALHGDFFNFY
Mflv_2102|M.gilvum_PYR-GCK          LKKTIDETDRAAGIVVADHEYFDNLINTLPDAYQVLARQ-GIYGDFFSFY
MAV_2533|M.avium_104                VKKVVHEADRTAGTMLADREWLEKYLDHWPDAFKILNRQ-GLYGDFFSFY
MSMEG_0347|M.smegmatis_MC2_155      LQNVVTQADRAAAIAVADHEYLDNILNTLPDKYRVLGRQ-AMYGDYFSFY
MAB_4152c|M.abscessus_ATCC_199      IKGTIEQARQLATRVDERKADVNVVVENLAENYLRLNAL-GAYGSFFNIY
                                    .   :             :  .:  :.  .     :    . :*.:  :*

Mb0176|M.bovis_AF2122/97            LCDLQIKWNGFQAGGPVRTVKLFSQP---TGRCTPQ--
MLBr_02590|M.leprae_Br4923          SCDITLKINGLQPGGPVRTVRLFQQP---TGRCTPQ--
MMAR_2883|M.marinum_M               LCDVVLKVNGK--GGQPVYIKVAGQA---TGRCTPK--
MUL_2869|M.ulcerans_Agy99           LCDVVLKVNGK--GGQPVYIKVAGQA---TGRCTPK--
Rv1967|M.tuberculosis_H37Rv         LCDVVLKVNGK--GGQPVYIKLAGQD---SGRCAPK--
Mvan_3981|M.vanbaalenii_PYR-1       LCELVLKLNGK--GGQPVYVKIAGQD---SGRCAPK--
TH_3704|M.thermoresistible__bu      LCEAVLKLNGK--GGQPVFVKIAGQP---TGRCTPK--
Mflv_2102|M.gilvum_PYR-GCK          LCDIVLKLNGK--GGQPVYVKVAGQS---SGRCAPR--
MAV_2533|M.avium_104                LCDIVLKLNGK--GGQPVYVKVAGQA---SGRCTPR--
MSMEG_0347|M.smegmatis_MC2_155      LCDLILKLNGK--GGQPVYVKLAEQV---TGRCAPK--
MAB_4152c|M.abscessus_ATCC_199      YCSIRIKVNGP--VGTDWLIPFGGPPDPSKGRCAFKNE
                                     *.  :* **    *    : .       .***: :

species	id	gene	e-value	identity (len)	annotation
M. thermoresistible (build 8)	TH_3704	-	-	100% (377)	virulence factor Mce family protein
M. thermoresistible (build 8)	TH_3222	-	e-121	63.13% (339)	PUTATIVE virulence factor Mce family protein
M. thermoresistible (build 8)	TH_3213	-	e-111	59.10% (335)	PUTATIVE virulence factor Mce family protein