For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
aa seq not available
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. thermoresistible (build 8) | TH_3099 | - | - | 100% (369) | putative acyl-CoA dehydrogenase |
| M. thermoresistible (build 8) | TH_0804 | - | 1e-65 | 42.22% (360) | acyl-CoA dehydrogenase |
| M. thermoresistible (build 8) | TH_3035 | - | 1e-63 | 39.62% (366) | PUTATIVE acyl-CoA dehydrogenase protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1968c | fadE18 | 7e-47 | 33.79% (364) | acyl-CoA dehydrogenase FADE18 |
| M. gilvum PYR-GCK | Mflv_0345 | - | 2e-60 | 38.40% (362) | acyl-CoA dehydrogenase domain-containing protein |
| M. tuberculosis H37Rv | Rv1933c | fadE18 | 7e-47 | 33.79% (364) | acyl-CoA dehydrogenase FADE18 |
| M. leprae Br4923 | MLBr_00737 | fadE25 | 7e-15 | 23.74% (358) | putative acyl-CoA dehydrogenase |
| M. abscessus ATCC 19977 | MAB_3123 | - | 5e-56 | 37.22% (360) | putative acyl-CoA dehydrogenase |
| M. marinum M | MMAR_1954 | fadE18_1 | 5e-54 | 37.64% (356) | acyl-CoA dehydrogenase FadE18_1 |
| M. avium 104 | MAV_2570 | - | 2e-54 | 36.48% (392) | putative acyl-CoA dehydrogenase |
| M. smegmatis MC2 155 | MSMEG_6585 | - | 1e-65 | 41.67% (372) | acyl-CoA dehydrogenase |
| M. ulcerans Agy99 | MUL_2176 | fadE18_1 | 3e-54 | 37.64% (356) | acyl-CoA dehydrogenase FadE18_1 |
| M. vanbaalenii PYR-1 | Mvan_0393 | - | 9e-61 | 40.22% (363) | acyl-CoA dehydrogenase domain-containing protein |
CLUSTAL 2.0.9 multiple sequence alignment
TH_3099|M.thermoresistible__bu ---------------------------------------MAPNAERDELR
MAV_2570|M.avium_104 -------------------------------------MTALSADERQELA
Mb1968c|M.bovis_AF2122/97 -------------------------------------MDFRYSTEQDDFR
Rv1933c|M.tuberculosis_H37Rv -------------------------------------MDFRYSTEQDDFR
Mflv_0345|M.gilvum_PYR-GCK --------------------------MAD-----TAG-EWVFSDEQNQLR
Mvan_0393|M.vanbaalenii_PYR-1 --------------------------MAD-----SQGAEYVFTEEQGQLR
MSMEG_6585|M.smegmatis_MC2_155 MAEELVDQPDKVAEELVDQPDKVAEELVDQPDKVAETTEFRFTDEQGQLR
MMAR_1954|M.marinum_M ----------------------------------MSTGDLLYSDTEEALR
MUL_2176|M.ulcerans_Agy99 ----------------------------------MSTGDLLYSDTEEALR
MAB_3123|M.abscessus_ATCC_1997 ------MSASEDHQTRMSASEDNQTRMSASEDNQAQINEFEFTEEHGDLR
MLBr_00737|M.leprae_Br4923 ---------------------------MVGWSGNPLFDLFKLPEEHNELR
. :
TH_3099|M.thermoresistible__bu SVVRKLLSQLASHEDVRRATETER---------GWSPELWATMHDEMSFG
MAV_2570|M.avium_104 QSVRSACERLASEDRVRAVAYAEGNRGGGDGHSGFDTVLWDVLCNQVGVA
Mb1968c|M.bovis_AF2122/97 ASLRGFLGRGAPVREMAAADGS-------------DRRLWQRLCTELELP
Rv1933c|M.tuberculosis_H37Rv ASLRGFLGRGAPVREMAAADGS-------------DRRLWQRLCTELELP
Mflv_0345|M.gilvum_PYR-GCK AAVRAFCADHVDESSVRAAMESDP---------PFDAKVWSRLGSELGVL
Mvan_0393|M.vanbaalenii_PYR-1 AAVRRFCADHIDETAVRAQMASEP---------RFDPKVWARLGSELGVL
MSMEG_6585|M.smegmatis_MC2_155 AAVRKFGAEYFDEQTVRRLMESEP---------RFDPAVWARLGAELGVL
MMAR_1954|M.marinum_M ASVGQLFAERCPPESVVAAYDSPP---------ADFAKLWRTLAAELGVA
MUL_2176|M.ulcerans_Agy99 ASVGQLFAERCPPESVVAAYDSPP---------ADFAKLWRTLAAELGVA
MAB_3123|M.abscessus_ATCC_1997 SLVRSWCERVWTPKHVRQIAEAGS----------VDLDAWRALGSELGVV
MLBr_00737|M.leprae_Br4923 ATIRALAEKEIAPHAADVDQRARF------------PEEALAALNASGFN
: : .
TH_3099|M.thermoresistible__bu AMAVPEARDGAGFGLRELAAVLEETGRALVSEPFLTAAVAVQ--AVTLAD
MAV_2570|M.avium_104 GIALPEHLGGAGYGVSALGVVAHELGRALAPVPFVGSTVLATGLLLDLTE
Mb1968c|M.bovis_AF2122/97 ALHVPPEHGGLGATLVETAIAFAELGRALTPIP-FAATVFAIEAILRMGD
Rv1933c|M.tuberculosis_H37Rv ALHVPPEHGGLGATLVETAIAFAELGRALTPIP-FAATVFAIEAILRMGD
Mflv_0345|M.gilvum_PYR-GCK GMAVPESAGGAGGNLVDQAVAVEQLGAALACGPLFGTVYLAIPALVAASG
Mvan_0393|M.vanbaalenii_PYR-1 GMSVPESHGGAGGTLVDQAVAVEQLGAALACGPLFGTVYLAIPALVASSQ
MSMEG_6585|M.smegmatis_MC2_155 GLAVPEADGGAGGTLVDQAVAVEELGAALACGPLIGTVYLSIPALVAASA
MMAR_1954|M.marinum_M GLLVPESLGGAGASAREAAVVMEEVGRAVAPVPFLSSAVLATVALLHSGE
MUL_2176|M.ulcerans_Agy99 GLLVPESLGGAGASAREAAVVMEEVGRAVAPVPFLSSAVLATVALLHSGE
MAB_3123|M.abscessus_ATCC_1997 GLSLPEQHGGGGLGVIELSIVAEELGRALACLPWISSAALGATALVSSGD
MLBr_00737|M.leprae_Br4923 AIHVPEEYGGQGADSVAACIVIEEVARVDASASLIPAVNKLGTMGLILRG
.: :* .* * . : . . . . . :. :
TH_3099|M.thermoresistible__bu ADEVGAEWLPALMSGETVAGADLRSP------APVTVTADTA------TG
MAV_2570|M.avium_104 RDPDADKRLTGLIEGRRTAAAALTGDGGLWRRSAVTLRAARAGDDWNIDG
Mb1968c|M.bovis_AF2122/97 DEQ-RKRLLAGLLTGARIGTIAVSGHDVASAT---TVRAVRRDGRPALTG
Rv1933c|M.tuberculosis_H37Rv DEQ-RKRLLAGLLTGARIGTIAVSGHDVASAT---TVRAVRRDGRPALTG
Mflv_0345|M.gilvum_PYR-GCK G----QELLGPLVDGTRTAAFAVRDDAGAFDASSVEVQAVPTEQGWALSG
Mvan_0393|M.vanbaalenii_PYR-1 P----GDLLAPLIEGIRTAAFAVPDAGGDFDADAVTVEAIPTDQGWTLTG
MSMEG_6585|M.smegmatis_MC2_155 GPV-RDELLGALVEGARTAAFAVPDRAGAFDPALVGVTASADAT---LTG
MMAR_1954|M.marinum_M T-----ETLSELAQGELTAALVVPLATAPGDP--VAGVSRGSAG---LSG
MUL_2176|M.ulcerans_Agy99 T-----ETLSELAQGELTAALVVPLATAPGDP--VAGASRGSAG---LSG
MAB_3123|M.abscessus_ATCC_1997 DSA-LAEWVPALAAGEKTITLAGGRTR---LADAITVSAESDTDGWKLTG
MLBr_00737|M.leprae_Br4923 SEELKKQVLPSLAAEGAMASYALSEREAGSDAASMRTRAKADGDDWILNG
: * : *
TH_3099|M.thermoresistible__bu SLTNVAHGGSLDVLVIAAT-EAGA----AGLYLVDLRAPEVKRQR-LQCL
MAV_2570|M.avium_104 TVRHVLGGSVADDLVVVAIDEDGE----PAVFLLDPTIDSVVAEA-ERVL
Mb1968c|M.bovis_AF2122/97 ECTPVLHGHVADLFVVPAVADGS-----IVLHVVAADAPGVTVTP-LPSF
Rv1933c|M.tuberculosis_H37Rv ECTPVLHGHVADLFVVPAVADGS-----IVLHVVAADAPGVTVTP-LPSF
Mflv_0345|M.gilvum_PYR-GCK TVERVVDAGAADVLLVAATTPDG-----VGLFVVEADSLGVQRIR-LTTL
Mvan_0393|M.vanbaalenii_PYR-1 TVQRVVDAGAADVVLVAAAGPDG-----LGLYAIEADNIGVQRIP-LTTL
MSMEG_6585|M.smegmatis_MC2_155 TVERIVDGAAADVFLVAATAPDG-----VALYAVDAS--DVQRTP-LTTL
MMAR_1954|M.marinum_M RVCGVAGAREADVLVVPVAGADG-----VELHTVRANAPGVEIVP-LLAF
MUL_2176|M.ulcerans_Agy99 RVCGVAGAREADVLVVPVAGADG-----VELHTVRANAPGVEIVP-LLAF
MAB_3123|M.abscessus_ATCC_1997 DTEHVPDGATADVILVLADTDSG-----PSLFAVDGDAPGVDRHS-LATL
MLBr_00737|M.leprae_Br4923 FKCWITNGGKSTWYTVMAVTDPDKGANGISAFIVHKDDEGFSIGPKEKKL
: . : . . . : . :
TH_3099|M.thermoresistible__bu DTTRPCATVTFEAAP----ARRLVGPDRFGPVLSRLRDFQAAALAAEHVG
MAV_2570|M.avium_104 DRTRPMATITLSSAP----ALRLSGDAPLGDVVDRNVDIALAVLSAEQVG
Mb1968c|M.bovis_AF2122/97 DITRPVATLRLAGSP----AEPLTAGTPDD--MERVLDVARVLLAAEMLG
Rv1933c|M.tuberculosis_H37Rv DITRPVATLRLAGSP----AEPLTAGTPDD--MERVLDVARVLLAAEMLG
Mflv_0345|M.gilvum_PYR-GCK DLTRPQATVGLLDAP----AQLIAGPEEAERVITHALQVGAALLAVEQVG
Mvan_0393|M.vanbaalenii_PYR-1 DLTRPQATVGLFHAP----ARLVAGPAEAERVITHALQIGAALLAVEQVG
MSMEG_6585|M.smegmatis_MC2_155 DLTRPQATIALTDTP----GRLVSGPGEAERVIGHALQVGAALLAVEQVG
MMAR_1954|M.marinum_M DMTRPLADVVFSGAA----SAPV-GLGSAEAALAEALQTGAALLASEQLG
MUL_2176|M.ulcerans_Agy99 DMTRPLADVVFSGAA----SAPV-GLGSAEAALAEALQTGAALLASEQLG
MAB_3123|M.abscessus_ATCC_1997 DMTRRQANIHFNSAP----ARLIGAQGRGAEAVATALDVAATVLAAEQAG
MLBr_00737|M.leprae_Br4923 GIKGSPTTELYFDKCRIPGDRIIGEPGTGFKTALATLDHTRPTIGAQAVG
. . : : : :. : *
TH_3099|M.thermoresistible__bu IIDRLLSTTREYLMTRRQFDRPLASFQAIKHRLADLLVDSERSRSAAEYA
MAV_2570|M.avium_104 ACERVLEIATDYARTREQFGRQIGSFQAIKHKCADMLVDLEWARSASQAA
Mb1968c|M.bovis_AF2122/97 GAEACLDLAVQYAGRRTQFDRPIGSFQAVKHACADMMIEIDATRATVMFA
Rv1933c|M.tuberculosis_H37Rv GAEACLDLAVQYAGRRTQFDRPIGSFQAVKHACADMMIEIDATRATVMFA
Mflv_0345|M.gilvum_PYR-GCK AAQHLLDLSVDYAKNRLQFGRPIGSFQAVKHRLADDLVAVEHARSTAYHA
Mvan_0393|M.vanbaalenii_PYR-1 AAQHLLDLTVDYAKNRLQFGRPIGSFQAVKHRLADDLVALEHARSTAYHA
MSMEG_6585|M.smegmatis_MC2_155 AAQHLLDLSVDYAKSRLQFGRPIGSFQAVKHRLADDLVDLEHARSAAYHA
MMAR_1954|M.marinum_M IAQWCFDTTLAYTKQRKQFGRAIGSYQAIKHRLADLWLEVGSARAAARYG
MUL_2176|M.ulcerans_Agy99 IAQWCFDTTLAYTKQRKQFGRAIGSYQAIKHRLADLWLEVGSARAAARYG
MAB_3123|M.abscessus_ATCC_1997 IAAHMLDVTTEYAKSRIQFGRIIGSFQAVKHRLADMAAATGNVRGAAYHA
MLBr_00737|M.leprae_Br4923 IAQGALDAAIVYTKDRKQFGESISTFQSIQFMLADMAMKVEAARLIVYAA
:. : * * **.. :.::*:::. ** * .
TH_3099|M.thermoresistible__bu AEAWDQS----TDDAPLAAAVASAVCTDAVIRTAHEAIQLHGGIAFTWEH
MAV_2570|M.avium_104 LEALDDPDSAAAGEAGWRASMAKAVCSEALRNATKANVQIHGGIGFTWED
Mb1968c|M.bovis_AF2122/97 AMSAANG-----DELQTVAPLAKAQTAETFVLCAGSALQIHGAIAFTWEH
Rv1933c|M.tuberculosis_H37Rv AMSAANG-----DELQTVAPLAKAQTAETFVLCAGSALQIHGAIAFTWEH
Mflv_0345|M.gilvum_PYR-GCK VWALSDGS----DDPALAVSIAQATTSAAFVRVATDTIQVHGGIGFTWEH
Mvan_0393|M.vanbaalenii_PYR-1 VWALTDGS----DDPALAVSIAQATCSEALVRVATDTIQVHGGIGFTWEH
MSMEG_6585|M.smegmatis_MC2_155 VWALADGS----DDPALAASIAQATASAALTKIATDTIQVHGGIGFTWEH
MMAR_1954|M.marinum_M ADTCARGD----EDAAIAAAIAAAYCGDVAVHAAEECVQLHGGIGMTWEY
MUL_2176|M.ulcerans_Agy99 ADTCARGD----EDAAIAAAIAAAYCGDVAVHAAEECVQLHGGIGMTWEY
MAB_3123|M.abscessus_ATCC_1997 AWSHDHPS---LDDPALATSIAQQVASAGAVEVTAKAIQSHGGIGFTWEH
MLBr_00737|M.leprae_Br4923 AARAERGE----PDLGFISAASKCFASDIAMEVTTDAVQLFGGAGYTSDF
: . : : :* .*. . * :
TH_3099|M.thermoresistible__bu EAHYYLRRALGDEALLGSARQARARIAELVG--LRADQPTEEKELT----
MAV_2570|M.avium_104 SAHLYFRRARTDEVLLGAPGQHWDRLSTLDPSTQPPASPEVTKELNDVDA
Mb1968c|M.bovis_AF2122/97 DLHLYYRRAKTTEALFGSSARNRALLAERAGLVKA---------------
Rv1933c|M.tuberculosis_H37Rv DLHLYYRRAKTTEALFGSSARNRALLAERAGLVKA---------------
Mflv_0345|M.gilvum_PYR-GCK QAHLYYKRAYTDAALLGGAEEHRARVADFVLVVAPEKD-----APRVATG
Mvan_0393|M.vanbaalenii_PYR-1 QAHLYYKRAYTDAALLGSAEAHRARVAELVLDVAPRKD-----APRVATG
MSMEG_6585|M.smegmatis_MC2_155 QAHLYFKRATTDAALLGTAEAHRDRIAELILDRAVSDQATIDRAPRVATG
MMAR_1954|M.marinum_M PAHLYLKRAKSDQLALGTAYRHRGRLAKLVNLPVS---------------
MUL_2176|M.ulcerans_Agy99 PAHLYLKRAKSDQLALGTAYRHRGRLAKLVNLPVS---------------
MAB_3123|M.abscessus_ATCC_1997 PAHLYYKRAVSNSALFGGRAVHAERIAKEVIDA-----------------
MLBr_00737|M.leprae_Br4923 PVERFMRDAKITQIYEGTNQIQRVVMSRALLR------------------
. : : * * ::
TH_3099|M.thermoresistible__bu --------------------------------------------------
MAV_2570|M.avium_104 LRAEIRSFLDNAPRPAGLRNYGPTPTADDVEAGRVWHRYLADHGYACLHW
Mb1968c|M.bovis_AF2122/97 --------------------------------------------------
Rv1933c|M.tuberculosis_H37Rv --------------------------------------------------
Mflv_0345|M.gilvum_PYR-GCK MPS-----------------------------------------------
Mvan_0393|M.vanbaalenii_PYR-1 MPS-----------------------------------------------
MSMEG_6585|M.smegmatis_MC2_155 TN------------------------------------------------
MMAR_1954|M.marinum_M --------------------------------------------------
MUL_2176|M.ulcerans_Agy99 --------------------------------------------------
MAB_3123|M.abscessus_ATCC_1997 --------------------------------------------------
MLBr_00737|M.leprae_Br4923 --------------------------------------------------
TH_3099|M.thermoresistible__bu --------------------------------------------------
MAV_2570|M.avium_104 PREFGGAAATVTYQAVFAEECARAEVPRQVNITGADLVGPVLIKFGSQEQ
Mb1968c|M.bovis_AF2122/97 --------------------------------------------------
Rv1933c|M.tuberculosis_H37Rv --------------------------------------------------
Mflv_0345|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_0393|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_6585|M.smegmatis_MC2_155 --------------------------------------------------
MMAR_1954|M.marinum_M --------------------------------------------------
MUL_2176|M.ulcerans_Agy99 --------------------------------------------------
MAB_3123|M.abscessus_ATCC_1997 --------------------------------------------------
MLBr_00737|M.leprae_Br4923 --------------------------------------------------
TH_3099|M.thermoresistible__bu --------------------------------------------------
MAV_2570|M.avium_104 KDRYLEPIRLGDDVWCQLFSEPGAGSDLAGVRTRAERTTTGWRIDGQKVW
Mb1968c|M.bovis_AF2122/97 --------------------------------------------------
Rv1933c|M.tuberculosis_H37Rv --------------------------------------------------
Mflv_0345|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_0393|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_6585|M.smegmatis_MC2_155 --------------------------------------------------
MMAR_1954|M.marinum_M --------------------------------------------------
MUL_2176|M.ulcerans_Agy99 --------------------------------------------------
MAB_3123|M.abscessus_ATCC_1997 --------------------------------------------------
MLBr_00737|M.leprae_Br4923 --------------------------------------------------
TH_3099|M.thermoresistible__bu --------------------------------------------------
MAV_2570|M.avium_104 SSAAASARFGLLLARTGPDKHRDLSMFVVPMDIPGVTVRPLTQMDGESKF
Mb1968c|M.bovis_AF2122/97 --------------------------------------------------
Rv1933c|M.tuberculosis_H37Rv --------------------------------------------------
Mflv_0345|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_0393|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_6585|M.smegmatis_MC2_155 --------------------------------------------------
MMAR_1954|M.marinum_M --------------------------------------------------
MUL_2176|M.ulcerans_Agy99 --------------------------------------------------
MAB_3123|M.abscessus_ATCC_1997 --------------------------------------------------
MLBr_00737|M.leprae_Br4923 --------------------------------------------------
TH_3099|M.thermoresistible__bu --------------------------------------------------
MAV_2570|M.avium_104 NEVFFDGAELDEDALIGEVGQGWTVAMVTLGRERLTLGSQAVSMFRLHER
Mb1968c|M.bovis_AF2122/97 --------------------------------------------------
Rv1933c|M.tuberculosis_H37Rv --------------------------------------------------
Mflv_0345|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_0393|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_6585|M.smegmatis_MC2_155 --------------------------------------------------
MMAR_1954|M.marinum_M --------------------------------------------------
MUL_2176|M.ulcerans_Agy99 --------------------------------------------------
MAB_3123|M.abscessus_ATCC_1997 --------------------------------------------------
MLBr_00737|M.leprae_Br4923 --------------------------------------------------
TH_3099|M.thermoresistible__bu --------------------------------------------------
MAV_2570|M.avium_104 MVDAARDHDLLDPVLSRSMTRLWARMWLLRFTWQRAIDSGDLTSPAFSVL
Mb1968c|M.bovis_AF2122/97 --------------------------------------------------
Rv1933c|M.tuberculosis_H37Rv --------------------------------------------------
Mflv_0345|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_0393|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_6585|M.smegmatis_MC2_155 --------------------------------------------------
MMAR_1954|M.marinum_M --------------------------------------------------
MUL_2176|M.ulcerans_Agy99 --------------------------------------------------
MAB_3123|M.abscessus_ATCC_1997 --------------------------------------------------
MLBr_00737|M.leprae_Br4923 --------------------------------------------------
TH_3099|M.thermoresistible__bu --------------------------------------------------
MAV_2570|M.avium_104 KLMTSETDQDLGDMATEVLGTDACTDPEEDGLVHHMLIGRAQTILGGTSE
Mb1968c|M.bovis_AF2122/97 --------------------------------------------------
Rv1933c|M.tuberculosis_H37Rv --------------------------------------------------
Mflv_0345|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_0393|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_6585|M.smegmatis_MC2_155 --------------------------------------------------
MMAR_1954|M.marinum_M --------------------------------------------------
MUL_2176|M.ulcerans_Agy99 --------------------------------------------------
MAB_3123|M.abscessus_ATCC_1997 --------------------------------------------------
MLBr_00737|M.leprae_Br4923 --------------------------------------------------
TH_3099|M.thermoresistible__bu ------------------
MAV_2570|M.avium_104 IQRNILGERVLGLPKEPR
Mb1968c|M.bovis_AF2122/97 ------------------
Rv1933c|M.tuberculosis_H37Rv ------------------
Mflv_0345|M.gilvum_PYR-GCK ------------------
Mvan_0393|M.vanbaalenii_PYR-1 ------------------
MSMEG_6585|M.smegmatis_MC2_155 ------------------
MMAR_1954|M.marinum_M ------------------
MUL_2176|M.ulcerans_Agy99 ------------------
MAB_3123|M.abscessus_ATCC_1997 ------------------
MLBr_00737|M.leprae_Br4923 ------------------