For questions or suggestions e-mail us at: ioerger@cs.tamu.edu

M. thermoresistible (build 8) TH_3035 (-)

annotation: acyl-CoA dehydrogenase protein
coordinates: 597828 - 598985
length: 386

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_3035--100% (386)acyl-CoA dehydrogenase protein
M. thermoresistible (build 8)TH_3429-e-14669.23% (377) PUTATIVE acyl-CoA dehydrogenase domain protein
M. thermoresistible (build 8)TH_4038-3e-6938.27% (371) PUTATIVE putative acyl-CoA dehydrogenase domain protein

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb1968cfadE181e-4635.42% (336) acyl-CoA dehydrogenase FADE18
M. gilvum PYR-GCKMflv_0345-6e-6740.44% (366) acyl-CoA dehydrogenase domain-containing protein
M. tuberculosis H37RvRv1933cfadE181e-4635.42% (336) acyl-CoA dehydrogenase FADE18
M. leprae Br4923MLBr_00737fadE251e-1221.77% (372) putative acyl-CoA dehydrogenase
M. abscessus ATCC 19977MAB_3123-7e-6439.57% (369) putative acyl-CoA dehydrogenase
M. marinum MMMAR_2861fadE182e-5035.75% (372) acyl-CoA dehydrogenase FadE18
M. avium 104MAV_1838-1e-14065.42% (373) acyl-CoA dehydrogenase protein
M. smegmatis MC2 155MSMEG_6585-2e-6541.53% (366) acyl-CoA dehydrogenase
M. ulcerans Agy99MUL_2893fadE183e-5035.75% (372) acyl-CoA dehydrogenase FadE18
M. vanbaalenii PYR-1Mvan_0393-5e-6339.89% (366) acyl-CoA dehydrogenase domain-containing protein

CLUSTAL 2.0.9 multiple sequence alignment


Mb1968c|M.bovis_AF2122/97           -------------------------------------MDFRYSTEQDDFR
Rv1933c|M.tuberculosis_H37Rv        -------------------------------------MDFRYSTEQDDFR
MMAR_2861|M.marinum_M               -------------------------------------MDFRYSTEQDDFR
MUL_2893|M.ulcerans_Agy99           -------------------------------------MDFRYSTEQDDFR
TH_3035|M.thermoresistible__bu      --------------------------MTT-----------LSIDERQQLA
MAV_1838|M.avium_104                --------------------------MTG-----------LSLDESRELA
Mflv_0345|M.gilvum_PYR-GCK          --------------------------MAD-----TAG-EWVFSDEQNQLR
Mvan_0393|M.vanbaalenii_PYR-1       --------------------------MAD-----SQGAEYVFTEEQGQLR
MSMEG_6585|M.smegmatis_MC2_155      MAEELVDQPDKVAEELVDQPDKVAEELVDQPDKVAETTEFRFTDEQGQLR
MAB_3123|M.abscessus_ATCC_1997      ------MSASEDHQTRMSASEDNQTRMSASEDNQAQINEFEFTEEHGDLR
MLBr_00737|M.leprae_Br4923          ---------------------------MVGWSGNPLFDLFKLPEEHNELR
                                                                                *  :: 

Mb1968c|M.bovis_AF2122/97           ASLRGFLGRGAP---VREMAAAD-----GSDRRLWQRLCTELELPALHVP
Rv1933c|M.tuberculosis_H37Rv        ASLRGFLGRGAP---VREMAAAD-----GSDRRLWQRLCTELELPALHVP
MMAR_2861|M.marinum_M               ESLRGFLRDQAPPARVRQVAAVG-----GHDKKLWHRLCAELELPALHAP
MUL_2893|M.ulcerans_Agy99           ESLRGFLRDQAPPARVRQVAAVG-----GHDKKLWHRLCAELELPALHAP
TH_3035|M.thermoresistible__bu      KSVRAACERLSSEERVRAVAYNGIHQHKGFDAELWTVLCSQVGVTAIALP
MAV_1838|M.avium_104                RSVRAACERFAPEERVRAIAYNGGGVDAGFDTELWKVLCAQVGVAAIGMP
Mflv_0345|M.gilvum_PYR-GCK          AAVRAFCADHVDESSVRAAMES----DPPFDAKVWSRLGSELGVLGMAVP
Mvan_0393|M.vanbaalenii_PYR-1       AAVRRFCADHIDETAVRAQMAS----EPRFDPKVWARLGSELGVLGMSVP
MSMEG_6585|M.smegmatis_MC2_155      AAVRKFGAEYFDEQTVRRLMES----EPRFDPAVWARLGAELGVLGLAVP
MAB_3123|M.abscessus_ATCC_1997      SLVRSWCERVWTPKHVRQIAEAG-----SVDLDAWRALGSELGVVGLSLP
MLBr_00737|M.leprae_Br4923          ATIRALAEKEIAPHAADVDQRAR------FPEEALAALN-ASGFNAIHVP
                                      :*           .                     *     . .:  *

Mb1968c|M.bovis_AF2122/97           PEHGGLGATLVETAIAFAELGRALTPIPFAATVFAIEAILRMG--DDEQR
Rv1933c|M.tuberculosis_H37Rv        PEHGGLGATLVETAIAFAELGRALTPIPFAATVFAIEAILRMG--DDEQR
MMAR_2861|M.marinum_M               PEYGGAGGTLVETAIAFGELGRALTPVPFAATILAIEAILRMG--DSEQR
MUL_2893|M.ulcerans_Agy99           PEYGGAGGTLVETAIAFGELGRALTPVPFAATILAIEAILRMG--DSEQR
TH_3035|M.thermoresistible__bu      ENLGGAGYGASALGAVAHELGRSLAAVPFVASAVLATTLLVAAQTEQPEV
MAV_1838|M.avium_104                EDLGGAGFDATALGVVAHELGRALAPVPFVASAVLATGLLLATRESDPDS
Mflv_0345|M.gilvum_PYR-GCK          ESAGGAGGNLVDQAVAVEQLGAALACGPLFGTVYLAIPALVAA-SGG---
Mvan_0393|M.vanbaalenii_PYR-1       ESHGGAGGTLVDQAVAVEQLGAALACGPLFGTVYLAIPALVAS-SQP---
MSMEG_6585|M.smegmatis_MC2_155      EADGGAGGTLVDQAVAVEELGAALACGPLIGTVYLSIPALVAA-SAGPVR
MAB_3123|M.abscessus_ATCC_1997      EQHGGGGLGVIELSIVAEELGRALACLPWISSAALGATALVSS-GDDSAL
MLBr_00737|M.leprae_Br4923          EEYGGQGADSVAACIVIEEVARVDASASLIPAVNKLGTMGLILRGSEELK
                                       ** *        .  ::.   :  .   :                  

Mb1968c|M.bovis_AF2122/97           KRLLAGLLTGARIGTIAV---SGHDVASATTVRAVRRDGRPALTGECTPV
Rv1933c|M.tuberculosis_H37Rv        KRLLAGLLTGARIGTIAV---SGHDVASATTVRAVRRDGRPALTGECTPV
MMAR_2861|M.marinum_M               KGLLSGLLSGDRIGALAA---AGPDLS-VTSVRAGRRDGRPVLTGECAPV
MUL_2893|M.ulcerans_Agy99           KGLLSGLLSGDRIGALAA---AGPDLS-VTSVRAGRRDGRPVLTGECAPV
TH_3035|M.thermoresistible__bu      DRRLAGLVEGSRTAAAVITSDGGLWRPDAIPVTAEQSTAGWVLTGTARHI
MAV_1838|M.avium_104                EQRLSGLMEGHRTAAAAVTGDGGLWQRDSVTLVANANIDGWAVNGTVRHV
Mflv_0345|M.gilvum_PYR-GCK          QELLGPLVDGTRTAAFAVRDDAGAFDASSVEVQAVPTEQGWALSGTVERV
Mvan_0393|M.vanbaalenii_PYR-1       GDLLAPLIEGIRTAAFAVPDAGGDFDADAVTVEAIPTDQGWTLTGTVQRV
MSMEG_6585|M.smegmatis_MC2_155      DELLGALVEGARTAAFAVPDRAGAFDPALVGVTASADAT---LTGTVERI
MAB_3123|M.abscessus_ATCC_1997      AEWVPALAAGEKTITLAG---GRTRLADAITVSAESDTDGWKLTGDTEHV
MLBr_00737|M.leprae_Br4923          KQVLPSLAAEGAMASYALSEREAGSDAASMRTRAKADGDDWILNGFKCWI
                                       :  *       : .                *        :.*    :

Mb1968c|M.bovis_AF2122/97           LHGHVADLFVVPAVAD-----GSIVLHVVAADAPGVTVTP-LPSFDITRP
Rv1933c|M.tuberculosis_H37Rv        LHGHVADLFVVPAVAD-----GSIVLHVVAADAPGVTVTP-LPSFDITRP
MMAR_2861|M.marinum_M               LHGHVADLFVVPAESD-----GAVILYVVDAAAPGVAVVG-LPSFDITRP
MUL_2893|M.ulcerans_Agy99           LHGHVADLFVVPAESD-----GAVILYVVDAAAPGVAVVG-LPSFDITRP
TH_3035|M.thermoresistible__bu      LHGSAADDLVVVATIG-----EVPALFVLDAMAPEVFRKD-EQVLDHTRP
MAV_1838|M.avium_104                LNGCAANDLVVVAKAD-----DQPALFLIDPMAEGVAVEA-ERVLDGTRP
Mflv_0345|M.gilvum_PYR-GCK          VDAGAADVLLVAATTP-----DGVGLFVVEADSLGVQRIR-LTTLDLTRP
Mvan_0393|M.vanbaalenii_PYR-1       VDAGAADVVLVAAAGP-----DGLGLYAIEADNIGVQRIP-LTTLDLTRP
MSMEG_6585|M.smegmatis_MC2_155      VDGAAADVFLVAATAP-----DGVALYAVDAS--DVQRTP-LTTLDLTRP
MAB_3123|M.abscessus_ATCC_1997      PDGATADVILVLADTD-----SGPSLFAVDGDAPGVDRHS-LATLDMTRR
MLBr_00737|M.leprae_Br4923          TNGGKSTWYTVMAVTDPDKGANGISAFIVHKDDEGFSIGPKEKKLGIKGS
                                     ..  :    * *             . :      .        :. .  

Mb1968c|M.bovis_AF2122/97           VATLRLAGSP----AEPLTAG--TPDDMERVLDVARVLLAAEMLGGAEAC
Rv1933c|M.tuberculosis_H37Rv        VATLRLAGSP----AEPLTAG--TPDDMERVLDVARVLLAAEMLGGAEAC
MMAR_2861|M.marinum_M               VAKLRLVRAP----AEALAAS--SADEVARLLDVARVLLAAEMLGGAEAC
MUL_2893|M.ulcerans_Agy99           VAKLRLVRAP----AEALAAS--SADEVARLLDVARVLLAAEMLGGAEAC
TH_3035|M.thermoresistible__bu      MATITFSSAP----ATLVSRRESIPELVSRTMDLTMAVLSAEQVGACERL
MAV_1838|M.avium_104                MATITFTGAT----ALKLTGREAVDTIIEHNIDVALAVLSAEQVGACERV
Mflv_0345|M.gilvum_PYR-GCK          QATVGLLDAP----AQLIAGPEEAERVITHALQVGAALLAVEQVGAAQHL
Mvan_0393|M.vanbaalenii_PYR-1       QATVGLFHAP----ARLVAGPAEAERVITHALQIGAALLAVEQVGAAQHL
MSMEG_6585|M.smegmatis_MC2_155      QATIALTDTP----GRLVSGPGEAERVIGHALQVGAALLAVEQVGAAQHL
MAB_3123|M.abscessus_ATCC_1997      QANIHFNSAP----ARLIGAQGRGAEAVATALDVAATVLAAEQAGIAAHM
MLBr_00737|M.leprae_Br4923          PTTELYFDKCRIPGDRIIGEPGTGFKTALATLDHTRPTIGAQAVGIAQGA
                                     :.              :             ::     :..:  * .   

Mb1968c|M.bovis_AF2122/97           LDLAVQYAGRRTQFDRPIGSFQAVKHACADMMIEIDATRATVMFAAMSAA
Rv1933c|M.tuberculosis_H37Rv        LDLAVQYAGRRTQFDRPIGSFQAVKHACADMMIEIDATRATVMFAAMSAA
MMAR_2861|M.marinum_M               LDLAIEYACSRKQFDRPIGSFQAVKHRCADMMIEIDATRAAVMFAQLCAA
MUL_2893|M.ulcerans_Agy99           LDLAIEYACSRKQFDRPIGSFQAVKHRCADMMIEIDATRAAVMFAQLCAA
TH_3035|M.thermoresistible__bu      LEISTEYARTRHQFNRPIGSFQAVKHKCADTLVDLEWARSASQAALEAMD
MAV_1838|M.avium_104                LEIACEYARTREQFGRPIGSFQAIKHKCADMLVDLEWARSASQAALEAVV
Mflv_0345|M.gilvum_PYR-GCK          LDLSVDYAKNRLQFGRPIGSFQAVKHRLADDLVAVEHARSTAYHAVWALS
Mvan_0393|M.vanbaalenii_PYR-1       LDLTVDYAKNRLQFGRPIGSFQAVKHRLADDLVALEHARSTAYHAVWALT
MSMEG_6585|M.smegmatis_MC2_155      LDLSVDYAKSRLQFGRPIGSFQAVKHRLADDLVDLEHARSAAYHAVWALA
MAB_3123|M.abscessus_ATCC_1997      LDVTTEYAKSRIQFGRIIGSFQAVKHRLADMAAATGNVRGAAYHAAWSHD
MLBr_00737|M.leprae_Br4923          LDAAIVYTKDRKQFGESISTFQSIQFMLADMAMKVEAARLIVYAAAARAE
                                    *: :  *:  * **.. *.:**:::.  **       .*     *     

Mb1968c|M.bovis_AF2122/97           NG--DELQTVAPLAKAQTAETFVLCAGSALQIHGAIAFTWEHDLHLYYRR
Rv1933c|M.tuberculosis_H37Rv        NG--DELQTVAPLAKAQTAETFVLCAGSALQIHGAIAFTWEHDLHLYYRR
MMAR_2861|M.marinum_M               GG--DELHATAPLAKAQAADTYVLCAGSAIQVHGGIAFTWEHDLHLYFRR
MUL_2893|M.ulcerans_Agy99           GG--DELHATAPLAKAQAAGTYVLCAGSAIQVHGGIAFTWEHDLHLYFRR
TH_3035|M.thermoresistible__bu      DGLTGESTWYASMAKAVCSEALQGAAHVNVQIHGGLGFTWEDSAHLYLRR
MAV_1838|M.avium_104                S---GERDWRASMAKAVCSESLRNAAHANVQIHGGIGFTWEDSAHLYLRR
Mflv_0345|M.gilvum_PYR-GCK          DG-SDDPALAVSIAQATTSAAFVRVATDTIQVHGGIGFTWEHQAHLYYKR
Mvan_0393|M.vanbaalenii_PYR-1       DG-SDDPALAVSIAQATCSEALVRVATDTIQVHGGIGFTWEHQAHLYYKR
MSMEG_6585|M.smegmatis_MC2_155      DG-SDDPALAASIAQATASAALTKIATDTIQVHGGIGFTWEHQAHLYFKR
MAB_3123|M.abscessus_ATCC_1997      HPSLDDPALATSIAQQVASAGAVEVTAKAIQSHGGIGFTWEHPAHLYYKR
MLBr_00737|M.leprae_Br4923          RG-EPDLGFISAASKCFASDIAMEVTTDAVQLFGGAGYTSDFPVERFMRD
                                         :     . ::   :      :   :* .*. .:* :   . : : 

Mb1968c|M.bovis_AF2122/97           AKTTEALFGSSARNRALLAERAGLVKA------------------
Rv1933c|M.tuberculosis_H37Rv        AKTTEALFGSSARNRALLAERAGLVKA------------------
MMAR_2861|M.marinum_M               AKTTEALFGSSAHHRSLLADRVGL---------------------
MUL_2893|M.ulcerans_Agy99           AKTTEALFGSSAHHRSLLADRVGL---------------------
TH_3035|M.thermoresistible__bu      ARTDEVLFGKPSEHWDRLALESGIFTGGNA------KR-------
MAV_1838|M.avium_104                ARTDEVLLGGPGQHWDRVGLR--VL--------------------
Mflv_0345|M.gilvum_PYR-GCK          AYTDAALLGGAEEHRARVADFVLVVAPEKD-----APRVATGMPS
Mvan_0393|M.vanbaalenii_PYR-1       AYTDAALLGSAEAHRARVAELVLDVAPRKD-----APRVATGMPS
MSMEG_6585|M.smegmatis_MC2_155      ATTDAALLGTAEAHRDRIAELILDRAVSDQATIDRAPRVATGTN-
MAB_3123|M.abscessus_ATCC_1997      AVSNSALFGGRAVHAERIAKEVIDA--------------------
MLBr_00737|M.leprae_Br4923          AKITQIYEGTNQIQRVVMSRALLR---------------------
                                    *       *    :   :.